CN107349364A - A kind of Chinese medicine composition and preparation method for being used to treat psoriasis - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of Chinese medicine composition for being used to treat psoriasis provided according to the understanding mechanism of Chinese traditional treatment psoriasis, each component and its mass parts ratio of the Chinese medicine composition are as follows：8~16g of schizonepeta, 15~46g of keel, windproof 8~16g, 3~6g of Chinese prickly ash, 9~35g of oyster, 3~6g of felwort, 5~12g of cicada slough, 6~18g of the root bark of shaggy-fruited dittany, 5~12g of sophora flower, 9~36g of coix seed, 9~16g of zaocys dhumnade, 8~16g of moutan bark, 5~10g of Asian puccoon, 6~12g of the tuber of dwarf lilyturf, 4~12g of the radix paeoniae rubrathe, 9~16g of radix rehmanniae recen, 15~28g of the capsule of weeping forsythia, 5~16g of the red sage root, 10~35g of dandelion, 10~60g of smilax, 8~16g of peach kernel, 3~12g of golden cypress, 9~16g of tiger battle, 15~28g of honeysuckle；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of Chinese medicine composition and preparation method for being used to treat psoriasis

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition for being used to treat psoriasis, particularly The Chinese medicine composition used for psoriatic and the field of preparation method.

Background technology

Doctor thinks：Psoriasis is commonly called as psoriasis, is a kind of chronic inflammatory skin, and the course of disease is longer, has easily recurrence to incline To some cases almost cannot be cured all one's life.The disease is fallen ill based on person between twenty and fifty, health on patient and mental status influence compared with Greatly.Clinical manifestation is with erythema, and based on the scales of skin that peel off, whole body can fall ill, and with scalp, it is relatively conventional that four limbs stretch side, aggravates in the winter time more.

Clinical manifestation：

A. psoriasis vulgaris

For a most common type, more acute onsets.Typical performance is the erythema that boundary understands, shape size differs, and around has inflammation Property blush.Slightly infiltration thickens.Surface covers the multilayer silvery white scales of skin that peel off.The scales of skin that peel off be easy to scrape it is de-, it is light red shinny semi-transparent after scraping Bright film, scratch the visible small blutpunkte of film（Auspitz's sign）.Skin lesion is apt to occur in head, sacrum portion and four limbs and stretches side.Suffer from part Person feels different degrees of itch.

B. psoriasis pustulosa

It is more rare, point general hair style and palm plantar type.Generalized pustular psoriasis are occur gregariousness superficial in erythema sterile Property warts, can partly be fused into purulence lake.Whole body can fall ill.Side is bent with four limbs and gauffer position is common, and mucous membrane of mouth can be simultaneously Involvement.Acute onset or be often accompanied by shivering with cold, generate heat when aggravating suddenly, arthralgia, general malaise and white blood cell count(WBC) increase Constitutional symptom.Is in periodical attack more, psoriasis vulgaris often occurs in the paracmasis.Palmoplantar pustulosis skin lesion is confined to Brothers, symmetrical to occur, general status is good, and the state of an illness is obstinate, recurrent exerbation

C. erythrodermic psoriasis

Also known as psoriatic exfoliative dermatitis, it is a kind of serious psoriasis.It is long-term a large amount of often because of the stronger medicine of external application excitant Using glucocorticoid, it is reduced caused by too fast or unexpected drug withdrawal.Show as whole skin and diffuse sexflush, swelling and furfur, companion There are the constitutional symptoms such as heating, chilly, discomfort, superficial lymph knot enlargement, white blood cell count(WBC) increases.

D. arthropathic psoriasis

Also known as psoriasis arthropathica.The joint damage of rheumatoid arthritis sample occurs simultaneously for psoriatic, can involve complete The big Minor articulus of body, but referred to end（Toe）Interphalangeal joints lesion most characteristic.Affected joints congestion and swelling pain, periarticular skin Also it is often red and swollen.Joint symptoms are often aggravated or mitigated simultaneously with skin symptom.Blood rheumatoid factor negative.

So, a kind of Chinese medicine composition for imitating treatment psoriasis how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment psoriasis, people gradually appreciate Chinese traditional treatment The advantages of psoriasis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment silver Consider the present situation of disease to be worth doing, the purpose of the present invention is to be to provide a kind of Chinese medicine composition for being used to treat psoriasis, to solve psoriasis The problem of patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts Than can effectively treat above-mentioned psoriasis.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating psoriasis Chinese medicine composition and preparation method, it is characterised in that each component and its mass parts of the Chinese medicine composition are than following institute Show：

8~16g of schizonepeta, 15~46g of keel, windproof 8~16g, 3~6g of Chinese prickly ash, 9~35g of oyster, 3~6g of felwort, cicada slough 5 ~12g, 6~18g of the root bark of shaggy-fruited dittany, 5~12g of sophora flower, 9~36g of coix seed, 9~16g of zaocys dhumnade, 8~16g of moutan bark, Asian puccoon 5~ 10g, 6~12g of the tuber of dwarf lilyturf, 4~12g of the radix paeoniae rubrathe, 9~16g of radix rehmanniae recen, 15~28g of the capsule of weeping forsythia, 5~16g of the red sage root, 10~35g of dandelion, 10~60g of smilax, 8~16g of peach kernel, 3~12g of golden cypress, 9~16g of tiger battle, 15~28g of honeysuckle.

A kind of Chinese medicine composition and preparation method for being used to treat psoriasis, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows：

10~14g of schizonepeta, 18~40g of keel, windproof 10~14g, 4~5.5g of Chinese prickly ash, 10~31g of oyster, felwort 4~ 5.5g, 6~11g of cicada slough, 7~15g of the root bark of shaggy-fruited dittany, 6~11g of sophora flower, 10~32g of coix seed, 10~14g of zaocys dhumnade, moutan bark 9~ 14g, 6~9g of Asian puccoon, 7~11g of the tuber of dwarf lilyturf, 5~11g of the radix paeoniae rubrathe, 10~14g of radix rehmanniae recen, 18~25g of the capsule of weeping forsythia, 6~14g of the red sage root, Pu Gong 11~31g of English, 11~52g of smilax, 9~14g of peach kernel, 5~11g of golden cypress, 10~14g of tiger battle, 18~25g of honeysuckle.

A kind of Chinese medicine composition and preparation method for being used to treat psoriasis, it is characterised in that " preferred plan " The each component and its mass parts of Chinese medicine composition are than as follows：

Schizonepeta 12g, keel 35g, windproof 12g, Chinese prickly ash 5g, oyster 28g, felwort 5g, cicada slough 10g, root bark of shaggy-fruited dittany 13g, sophora flower 10g, coix seed 28g, zaocys dhumnade 12g, moutan bark 12g, Asian puccoon 8g, tuber of dwarf lilyturf 10g, radix paeoniae rubrathe 10g, radix rehmanniae recen 12g, capsule of weeping forsythia 22g, pellet Join 12g, dandelion 28g, smilax 45g, peach kernel 122g, golden cypress 10g, tiger battle 12g, honeysuckle 22g.

A kind of Chinese medicine composition and preparation method for being used to treat psoriasis, it is characterised in that methods described includes as follows Step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 60min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 66mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 35 min, leaching decoction；2. the tepor boiling water that medicine 62mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 30 min, leaching decoction；It is condensed into 3. decoction twice is mixed in 50% Decoction 450ml（Milliliter）.

It is a kind of to be used to treat the Chinese medicine composition and preparation method of psoriasis, it is characterised in that the instructions of taking is：Will The herb liquid prepared was taken with one day, one portion per day, morning and evening sub-service, dosage 190ml（Milliliter）/ time, morning, supper are later half small When take（Children, old man, Pregnant and lactant women use with caution）, avoid eating beef, dog meats, wine, cured fish, sauce, peppery etc..One month is one The course for the treatment of, while available remaining herb liquid elution affected part, daily/time, 3~6 courses for the treatment of are treated, symptom gradually mitigates or obtained temporarily Cure.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Schizonepeta, nature and flavor：It is pungent, warm, have deliver, wind-dispelling, regulating blood condition, fries charcoal hemostasis the effect of, for treat cold, fever, headache, Abscess of throat, apoplexy lockjaw, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, the disease such as scrofula；

Keel, nature and flavor：It is sweet, puckery, flat, there is the effect of calmness, puckery essence of arrest sweating, myogenic sore, for treating neurasthenia, the heart Throb with fear, have a sleepless night, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, uterine bleeding, band under, sore burst for a long time and does not holds back is controlled in external application；

It is windproof, nature and flavor：Acrid flavour, sweet, slightly warm in nature, have expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, it is antipruritic the effect of, it is outer for treating Feel chill, headache bodily pain, arthralgia pain due to rheumatism, skeletal pain, stomachache diarrhea, discharging fresh blood stool, lockjaw, rubella itch, sore from the beginning of；

Chinese prickly ash, nature and flavor：It is pungent, warm, there is the effect of warm in pain, desinsection is antipruritic, for treating coldness and pain in the epigastrium, vomiting and diarrhea, worm Product stomachache, ascariasis, control eczema itch outside；

Oyster, nature and flavor：It is salty, be slightly cold, have transquilization with heavy material, checking exuberance of yang tonifying yin, softening and resolving hard mass the effect of, for treat insomnia of palpitating with fear, Dizziness and tinnitus, scrofula subcutaneous nodule, abdominal mass lump in the abdomen, calcined oyster shell convergence is astringent or styptic treatment for spontaneous sweating, collapses band, stomachache acid regurgitation for spontaneous sweating, seminal emission；

Felwort, nature and flavor：It is bitter, cold in nature, there is heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage effect of fire, for treating heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage Fire, it is additionally operable under jaundice with damp-heat pathogen, swelling of vulva pruritus vulvae, band, eczema itch, irascibility hot eyes, Hiccough and deaf, hypochondriac pain bitter taste, persistent erection, infantile convulsion Twitch；

Cicada slough, nature and flavor：It is sweet, salty, cool in nature, there is the effect of dispelling wind-heat, promoting eruption relieving sore-throat, removing nebula for improving eyesight, expelling wind and relieving convulsion, be used for Treat anemopyretic cold, abscess of throat, cough sound is mute, single board computer rash is impermeable, rubella itch, cataract, twitch, lockjaw Deng disease；

The root bark of shaggy-fruited dittany, nature and flavor：It is bitter, salty, cold, there is the effect of heat-clearing and damp-drying drug, dispelling wind and arresting itching, removing toxic substances, for treating wind-heat wet poison institute The diseases such as the rubella of cause, eczema, mange, jaundice, damp-heat arthralgia；

Sophora flower, nature and flavor：It is bitter, be slightly cold, there is the effect of cooling blood and hemostasis, clearing liver-fire, have blood in stool, hemorrhoid blood, bloody flux, collapse for treating Leakage, haematemesis, bleeding from five sense organs or subcutaneous tissue, the hot hot eyes of liver, dizziness of having a headache；

Coix seed, nature and flavor：It is sweet, light, cool, there is the effect of invigorating the spleen excreting dampness, remove numbness antidiarrheal, dense heat-clearing row, for treating oedema, pin The diseases such as gas, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis, flat wart；

Zaocys dhumnade, nature and flavor：It is sweet, flat, there is wind-dispelling, dredging collateral, stop the effect of convulsion, for rheumatoid arthritis stubborn, numbness contracture, apoplexy, mouth The diseases such as eye is crooked, hemiplegia, twitch spasm, lockjaw, leprosy mange, scrofula malignant sore；

Moutan bark, nature and flavor：It is arduous, cool, there is the effect of heat-clearing, cool blood and blood, dispersing blood stasis, for treat heat invading xuefen, hair spot, Frightened epilepsy, tell, be defeated in battle, having blood in stool, hectic fever due to yin labor heat, Amenorrhea, abdominal mass, large carbuncle, flutter damage etc. disease；

Asian puccoon, nature and flavor：It is sweet, salty, cold, there is the effect of cool blood, promoting blood circulation, removing toxic substances promoting eruption, it is purple for treating blood-heat and toxin exuberance, macula Black, measles without adequate eruption, sore, eczema, scald；

The tuber of dwarf lilyturf, nature and flavor：Sweet, slight bitter, it is slightly cold, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease The diseases such as cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

Radix rehmanniae recen, nature and flavor：It is sweet, cold, there is the effect of clearing heat and cooling blood, yin-nourishing, promote the production of body fluid, for treating the deep red polydipsia of pyreticosis tongue, the deficiency of Yin Interior heat, hectic fever due to yin labor heat, Heat Diabetes, haematemesis, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis；

The capsule of weeping forsythia, nature and flavor：It is bitter, cool, there is the effect of heat-clearing, removing toxic substances, dissipating bind, detumescence, for treating warm, erysipelas, macula, large carbuncle Pyogenic infections, scrofula, urine leaching closes；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters the diseases such as ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Dandelion, nature and flavor：Bitter；It is sweet, cold in nature, there is the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind, for treating acute mastitis, lung carbuncle, intestines Carbuncle, mumps, boil poisonous soreness, red eye, swell pain, cold, fever, cough, abscess of throat, stomach fire, enteritis, dysentery, hepatitis, courage frighten it is scorching, Urinary tract infections, snake bite and insect sting；

Smilax, nature and flavor：It is sweet light, flat, there is the effect of removing damp-heat, let out turbid removing toxic substances, be easing joint movement, for treating syphilis, leaching Turbid, diarrhea, muscles and bones contraction pain, tinea pedis, carbuncle swells, sore tinea, scrofula, goiter and tumor and mercury poisoning；

Peach kernel, nature and flavor：Bitter sweet, put down, it is nontoxic, there is the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis Store blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood；

Golden cypress, nature and flavor：It is bitter, cold, there is the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating, for treating damp-heat dysentery, diarrhea, jaundice, dream Something lost, stranguria with turbid discharge, band under, hectic fever due to yin labor heat and aphthae, red eye, swell pain, skin sore, skin eczema；

Tiger battle, nature and flavor：Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；

Honeysuckle, nature and flavor：It is sweet, cold, have it is clearing heat and detoxicating the effect of, for treat warm disease heating, toxic-heat and blood stasis, carbuncle swells furunculosis, Larynx numbness and multi-infection disease.

Medicine of the present invention is the principle based on Chinese traditional treatment psoriasis, from the pathomechanism according to psoriasis and pharmacological action Think：With regard to psoriasis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned psoriasis, the medicine prepared using the formula Thing good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of Chinese medicine composition for being used to treat psoriasis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：

Schizonepeta 12g, keel 35g, windproof 12g, Chinese prickly ash 5g, oyster 28g, felwort 5g, cicada slough 10g, root bark of shaggy-fruited dittany 13g, sophora flower 10g, coix seed 28g, zaocys dhumnade 12g, moutan bark 12g, Asian puccoon 8g, tuber of dwarf lilyturf 10g, radix paeoniae rubrathe 10g, radix rehmanniae recen 12g, capsule of weeping forsythia 22g, pellet Join 12g, dandelion 28g, smilax 45g, peach kernel 122g, golden cypress 10g, tiger battle 12g, honeysuckle 22g.Embodiment 2：

A kind of Chinese medicine composition for being used to treat psoriasis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：

Schizonepeta 14g, keel 40g, windproof 14g, Chinese prickly ash 5.5g, oyster 31g, felwort 5.5g, cicada slough 11g, root bark of shaggy-fruited dittany 15g, Chinese scholartree Flower 11g, coix seed 32g, zaocys dhumnade 14g, moutan bark 14g, Asian puccoon 9g, tuber of dwarf lilyturf 11g, radix paeoniae rubrathe 11g, radix rehmanniae recen 14g, capsule of weeping forsythia 25g, Red sage root 14g, dandelion 31g, smilax 52g, peach kernel 14g, golden cypress 11g, tiger battle 14g, honeysuckle 25g.

Embodiment 3：

A kind of Chinese medicine composition for being used to treat psoriasis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：

Schizonepeta 16g, keel 46g, windproof 16g, Chinese prickly ash 6g, oyster 35g, felwort 6g, cicada slough 12g, root bark of shaggy-fruited dittany 18g, sophora flower 12g, coix seed 36g, zaocys dhumnade 16g, moutan bark 16g, Asian puccoon 10g, tuber of dwarf lilyturf 12g, radix paeoniae rubrathe 12g, radix rehmanniae recen 16g, capsule of weeping forsythia 28g, Red sage root 16g, dandelion 35g, smilax 60g, peach kernel 16g, golden cypress 12g, tiger battle 16g, honeysuckle 28g.

Model case

Through clinical conditions psoriatic totally 680, the age is 460 of more than 33 years old, only 220 for 33 years old with Under.Obtain 400 temporarily cured in 680 patients, effective 246, invalid 34.Total effective rate is up to 95%.

Claims (3)

1. a kind of be used to treat the Chinese medicine composition of psoriasis, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：

8~16g of schizonepeta, 15~46g of keel, windproof 8~16g, 3~6g of Chinese prickly ash, 9~35g of oyster, 3~6g of felwort, cicada slough 5 ~12g, 6~18g of the root bark of shaggy-fruited dittany, 5~12g of sophora flower, 9~36g of coix seed, 9~16g of zaocys dhumnade, 8~16g of moutan bark, Asian puccoon 5~ 10g, 6~12g of the tuber of dwarf lilyturf, 4~12g of the radix paeoniae rubrathe, 9~16g of radix rehmanniae recen, 15~28g of the capsule of weeping forsythia, 5~16g of the red sage root, 10~35g of dandelion, 10~60g of smilax, 8~16g of peach kernel, 3~12g of golden cypress, 9~16g of tiger battle, 15~28g of honeysuckle.

2. the Chinese medicine composition according to claim 1 for being used to treat psoriasis, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：

10~14g of schizonepeta, 18~40g of keel, windproof 10~14g, 4~5.5g of Chinese prickly ash, 10~31g of oyster, felwort 4~ 5.5g, 6~11g of cicada slough, 7~15g of the root bark of shaggy-fruited dittany, 6~11g of sophora flower, 10~32g of coix seed, 10~14g of zaocys dhumnade, moutan bark 9~ 14g, 6~9g of Asian puccoon, 7~11g of the tuber of dwarf lilyturf, 5~11g of the radix paeoniae rubrathe, 10~14g of radix rehmanniae recen, 18~25g of the capsule of weeping forsythia, 6~14g of the red sage root, Pu Gong 11~31g of English, 11~52g of smilax, 9~14g of peach kernel, 5~11g of golden cypress, 10~14g of tiger battle, 18~25g of honeysuckle.

3. the Chinese medicine composition for being used to treat psoriasis according to claim 1 to 2, it is characterised in that the Chinese medicine group The each component and its mass parts of compound are than as follows：

Schizonepeta 12g, keel 35g, windproof 12g, Chinese prickly ash 5g, oyster 28g, felwort 5g, cicada slough 10g, root bark of shaggy-fruited dittany 13g, sophora flower 10g, coix seed 28g, zaocys dhumnade 12g, moutan bark 12g, Asian puccoon 8g, tuber of dwarf lilyturf 10g, radix paeoniae rubrathe 10g, radix rehmanniae recen 12g, capsule of weeping forsythia 22g, pellet Join 12g, dandelion 28g, smilax 45g, peach kernel 122g, golden cypress 10g, tiger battle 12g, honeysuckle 22g.