CN107375730B - 一种银翘袋泡剂的制备方法 - Google Patents
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Abstract
本发明公开了一种银翘袋泡剂的制备方法，步骤为：(1)按重量配比取各原料组分：金银花0.8‑1.6份、连翘0.8‑16份、薄荷0.5‑0.9份、荆芥0.3‑0.5份、牛蒡子0.5‑0.9份、桔梗0.7‑0.9份、淡豆豉0.5‑0.8份、芦根0.5‑0.9份、淡竹叶0.3‑0.6份、甘草0.5‑0.8份；(2)将连翘、牛蒡子、淡豆豉、甘草粉碎，过65目筛；将金银花、薄荷、荆芥、桔梗、芦根、淡竹叶粉碎，过24目筛；灭菌；(3)取药粉置于槽型混合机中，加入水，搅拌，混合均匀，进一步制成软材、湿颗粒，制粒筛网为12目；将湿颗粒置入沸腾干燥机干燥至水分≤12％，冷却；(4)用摇摆颗粒机整粒，筛网目数为10目，送入混合机内混合，出料、称量、计重，分装入茶叶袋中。本发明方法制备的银翘袋泡剂浸出率高、生产效率高、细粉少、易成型、口感好。
Description
技术领域
本发明涉及一种食品制备领域，特别是涉及一种银翘袋泡剂的制备方法。
背景技术
当今人们生活节奏越来越快，承担的压力越来越大，与之相反的，人们特别是一线城市上班族越来越缺乏运动锻炼，处于亚健康状态的人越来越多，所以通过食用日常食品、饮品来达到健康养生的方式也被重视起来。因此，具有辛凉解表，清热解毒等功能的银翘茶广受人们的欢迎。但传统连翘茶针对普遍大众，一般只能发挥清热解毒的基本功效，不能针对上班族压力大、失眠、易疲惫等特点发挥效用。并且传统银翘茶有效成分浸出速度慢，浸出率低，与现代社会的高节奏生活不相适应，连翘茶的有效成分不能完全被利用，造成浪费较高。并且现有的银翘袋泡剂存在易散、细粉较多的缺点，使银翘袋泡剂的药效和口感大打折扣。
因此本领域技术人员致力于开发一种浸出率高、生产效率高、细粉少、易成型、口感好的银翘袋泡剂的制备方法。
发明内容
有鉴于现有技术的上述缺陷，本发明所要解决的技术问题是提供一种浸出率高、生产效率高、细粉少、易成型、口感好的银翘袋泡剂的制备方法。
为实现上述目的，本发明提供了一种银翘袋泡剂的制备方法，包括以下步骤：
(1)按以下重量配比称取各原料组分：
金银花0.8-1.6份、连翘0.8-16份、薄荷0.5-0.9份、荆芥0.3-0.5份、牛蒡子0.5-0.9份、桔梗0.7-0.9份、淡豆豉0.5-0.8份、芦根0.5-0.9份、淡竹叶0.3-0.6份、甘草0.5-0.8份；
(2)粉碎：将所述连翘、牛蒡子、淡豆豉、甘草粉碎，过65目筛；将所述金银花、薄荷、荆芥、桔梗、芦根、淡竹叶粉碎，过24目筛；灭菌；
(3)制粒、干燥：取药粉置于槽型混合机中，加入适量纯化水，低速搅拌，混合均匀，制成软材，软材通过摇摆颗粒机制湿颗粒，制粒筛网为12目；
将所述湿颗粒置入沸腾干燥机干燥至水分≤12％，停止干燥，冷却；
(4)整粒、总混、分装：用摇摆颗粒机整粒，筛网目数为10目，送入混合机内混合，出料、称量、计重，分装入由茶叶滤纸、复合膜构成的茶叶袋中。
各原料组分重量配比优选为：金银花1.5份、连翘0.8份、薄荷0.7份、荆芥0.3份、牛蒡子0.7份、桔梗0.9份、淡豆豉0.8份、芦根0.9份、淡竹叶0.5份、甘草0.8份。
本发明所选取的原料具有如下特性与功能：
金银花：甘，寒。归肺、心、胃经。清热解毒，疏散风热。用于痈肿疔疮，喉痹，丹毒，热毒血痢，风热感冒，温病发热。
连翘：辛、苦，热；有小毒。归肝、脾、胃、肾经。散寒止痛，降逆止呕，用于厥阴头痛，寒疝腹痛，寒湿脚气，经行腹痛，脘腹胀痛，呕吐吞酸，五更泄泻。
薄荷：辛、凉。归肺、肝经。疏散风热，清利头目，利咽，透疹，疏肝行气。用于风热感冒，风温初起，头痛，目赤，喉痹，口疮，风疹，麻疹，胸胁胀闷。
荆芥：辛、涩，微温。归肺、肝经。收敛止血。用于便血，崩漏产后血晕。
牛蒡子：辛、苦、寒。归肺、胃经。疏散风热，宣肺透疹，解毒利咽。用于风热感冒，咳嗽痰多，麻疹，风疹，咽喉肿痛，痄腮，丹毒，痈肿疮毒。
桔梗：苦、辛，平。归肺经。宣肺，利咽，祛痰，排脓。用于咳嗽痰多，胸闷不畅，咽痛音哑，肺痈吐脓。
淡豆豉：苦、辛，凉。归肺、胃经。解表，除烦，宣发郁热。用于感冒，寒热头痛，烦躁胸闷，虚烦不眠。
芦根：甘，寒。归肺、胃经。清热泻火，生津止渴，除烦，止呕，利尿。用于热病烦渴，肺热咳嗽，肺痈吐脓，胃热呕哕，热淋涩痛。
淡竹叶：甘、淡，寒。归心、胃、小肠经。清热泻火，除烦止渴，利尿通淋。用于热病烦渴，小便短赤涩痛，口舌生疮。
甘草：甘，平。归心、肺、脾、胃经。补脾益气，淸热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
本发明的有益效果是：
①本发明方法制备的银翘袋泡剂不但具有辛凉解表，清热解毒等功效，能预防风热感冒，发热头痛，咳嗽，口干，咽喉疼痛等病症，更具有养胃、醒神、静气、改善睡眠状况等功效，特别适宜城市上班族。
②各原料的有效成分快速浸出，浸出更彻底。
③制粒过程中成型更加容易，干燥后不易散，细粉少。
④相对于传统制法中只能采用热风循环烘箱进行干燥，本发明方法的制备过程中可以采用沸腾干燥机进行干燥，干燥时间短，劳动强度小，易挥发成分流失小，质量稳定，工作效率进一步得到提高。
具体实施方式
下面结合实施例对本发明作进一步说明，此处所描述的实施例仅用以解释本发明，并不用以限定本发明：
实施例1：
一种银翘袋泡剂的制备方法，包括以下步骤：
(1)按以下重量配比称取各原料组分：
金银花1.5份、连翘0.8份、薄荷0.7份、荆芥0.3份、牛蒡子0.7份、桔梗0.9份、淡豆豉0.8份、芦根0.9份、淡竹叶0.5份、甘草0.8份；
(2)粉碎：将所述连翘、牛蒡子、淡豆豉、甘草粉碎，过65目筛；将所述金银花、薄荷、荆芥、桔梗、芦根、淡竹叶粉碎，过24目筛；灭菌；
(3)制粒、干燥：取药粉置于槽型混合机中，加入适量纯化水，低速搅拌，混合均匀，制成软材，软材通过摇摆颗粒机制湿颗粒，制粒筛网为12目；
将所述湿颗粒采用沸腾干燥机干燥至水分为10％，停止干燥，冷却；
(4)整粒、总混、分装：用摇摆颗粒机整粒，筛网目数为10目，送入混合机内混合，出料、称量、计重，分装入由茶叶滤纸、复合膜构成的茶叶袋中。
实施例2-10
实施例2-10各原料组分重量配比见表1，其他操作参数在本发明限定范围内随机选择。
表1实施例2-10各原料重量配比表
以上这实施例都制备出了符合本发明目的的银翘袋泡剂。
另设对比例1-10，1＇-10＇，对比例1-10与1＇-10＇中各原料组分与实施例1-10分别对应相同，其中对比例1-10按照传统方法制备出相应银翘袋泡剂；对比例1＇-10＇在步骤(2)粉碎过程中，所有原料都粉碎后过80目筛。制成相应银翘袋泡剂后，对实施例1-10、对比例1-10和对比例1＇-10＇取相同重量的银翘袋泡剂，按照《中国药典》2015版四部通则2221——浸出物测定法中的热浸法，分别测定实施例1-10与对比例1-10、1＇-10＇中各原料组分的浸出率，结果见表2-表4：
表2：实施例1-10各原料组分的浸出率列表
表3：对比例1-10各原料组分的浸出率列表
表4：对比例1＇-10＇各原料组分的浸出率列表
将实施例1-10与对比例1-10、对比例1＇-10＇银翘袋泡剂各原料组分的浸出率平均值进行比较，比较结果见表5。
表5：实施例1-10与对比例1-10、对比例1＇-10＇银翘袋泡剂各原料组分的浸出率平均值比较表
通过以上实施例与对比例的比较可知，使用本发明方法，对连翘、牛蒡子、淡豆鼓、甘草在粉碎环节粉碎到过65目筛，能使它们的浸出率得到显著提高，其他原料成分浸出率则没有明显提高。进一步的，将所有原料成分都粉碎到过80目筛，浸出率则基本没有更为明显的提高，并且粉碎到过80目筛也不利于工时的节省和生产效率的提高。
使用本发明方法，通过适当加大对部分原料的研磨程度，能使银翘袋泡剂各原料成分在最短加工时间，同等加工步骤下浸出率均达到最大，同时针对不同的原料成分，采用不同的加工方法，成本也得到了有效控制。而相比传统制法，各原料有效成份浸出更加彻底，提高了银翘袋泡剂的品质。
以上实施例与对比例还进一步表明，本发明方法使银翘袋泡剂中对厥阴头痛、腹胀有重要疗效的连翘；对风热感冒有治疗作用的牛蒡子；对缓解及治疗烦躁胸闷、虚烦不眠有重要作用的淡豆豉；对脾胃虚弱、倦怠乏力具有重要疗效的甘草的浸出率得到了显著提高，综合起来，能更有效地改善对城市上班族因压力大、工作强度高引起的失眠、易疲惫、脾胃虚弱的亚健康状态。
同时，通过对实施例1-10与对比例1-10、对比例1＇-10＇制粒成功率进行比较，结果见表6，其中，制粒成功率是指通过一次性制粒即合格的干燥后颗粒成品(不包括细粉及不能通过制粒筛网的材料)与所有软材干燥后的比值。
表6实施例1-10与对比例1-10、对比例1＇-10＇制粒成功率比较表
| 对比例1-10 | 制粒成功率 | 实施例1-10 | 制粒成功率 | 对比例1＇-10＇ | 制粒成功率 |
| 对比例1 | 74.5％ | 实施例1 | 98.2％ | 对比例1＇ | 96.2％ |
| 对比例2 | 80.3％ | 实施例2 | 97.5％ | 对比例2＇ | 90.8％ |
| 对比例3 | 79.6％ | 实施例3 | 97.14％ | 对比例3＇ | 89.68％ |
| 对比例4 | 78.22％ | 实施例4 | 96.58％ | 对比例4＇ | 91.62％ |
| 对比例5 | 76.59％ | 实施例5 | 96.36％ | 对比例5＇ | 94.33％ |
| 对比例6 | 81.25％ | 实施例6 | 97.51％ | 对比例6＇ | 93.1％ |
| 对比例7 | 76.9％ | 实施例7 | 94.85％ | 对比例7＇ | 95.58％ |
| 对比例8 | 81.5％ | 实施例8 | 97.32％ | 对比例8＇ | 94.35％ |
| 对比例9 | 76.91％ | 实施例9 | 95.85％ | 对比例9＇ | 93.52％ |
| 对比例10 | 74.32％ | 实施例10 | 96.35％ | 对比例10＇ | 90.85％ |
| 平均值 | 78.01％ | 平均值 | 96.77％ | 平均值 | 93％ |
通过对实施例1-10与对比例1-10、对比例1＇-10＇制粒成功率比较可知，采用本发明方法，制粒成功率达到最高，相对对比例1-10，提高率达到24.05％，相对对比例1＇-10＇，提高率达到4.1％，且对比例1＇-10＇需要的加工成本更高，制备效率远低于本发明方法。
同时，本发明方法的银翘袋泡剂通过调节和原料成分的比例，更具有针对性，对现代社会高压、过劳的人群更为适用，且本发明方法能够适用于大规模生产，能够实施。
以上详细描述了本发明的较佳具体实施例。应当理解，本领域的普通技术人员无需创造性劳动就可以根据本发明的构思作出诸多修改和变化。因此，凡本技术领域中技术人员依本发明的构思在现有技术的基础上通过逻辑分析、推理或者有限的实验可以得到的技术方案，皆应在由权利要求书所确定的保护范围内。
Claims (2)
1.一种银翘袋泡剂的制备方法，其特征是，包括以下步骤：
(1)按以下重量配比称取各原料组分：
金银花0.8-1.6份、连翘0.8-16份、薄荷0.5-0.9份、荆芥0.3-0.5份、牛蒡子0.5-0.9份、桔梗0.7-0.9份、淡豆豉0.5-0.8份、芦根0.5-0.9份、淡竹叶0.3-0.6份、甘草0.5-0.8份；
(2)粉碎：将所述连翘、牛蒡子、淡豆豉、甘草粉碎，过65目筛；将所述金银花、薄荷、荆芥、桔梗、芦根、淡竹叶粉碎，过24目筛；灭菌；
(3)制粒、干燥：取药粉置于槽型混合机中，加入适量纯化水，低速搅拌，混合均匀，制成软材，软材通过摇摆颗粒机制湿颗粒，制粒筛网为12目；
将所述湿颗粒置入沸腾干燥机干燥至水分≤12％，停止干燥，冷却；
(4)整粒、总混、分装：用摇摆颗粒机整粒，筛网目数为10目，送入混合机内混合，出料、称量、计重，分装入由茶叶滤纸、复合膜构成的茶叶袋中。
2.如权利要求1所述的制备方法，其特征是：所述步骤(1)中，各原料组分重量配比为：金银花1.5份、连翘0.8份、薄荷0.7份、荆芥0.3份、牛蒡子0.7份、桔梗0.9份、淡豆豉0.8份、芦根0.9份、淡竹叶0.5份、甘草0.8份。
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