CN107375706A - A kind of capsule medicine for treating chronic bronchitis and preparation method thereof - Google Patents
A kind of capsule medicine for treating chronic bronchitis and preparation method thereof Download PDFInfo
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- CN107375706A CN107375706A CN201710652122.2A CN201710652122A CN107375706A CN 107375706 A CN107375706 A CN 107375706A CN 201710652122 A CN201710652122 A CN 201710652122A CN 107375706 A CN107375706 A CN 107375706A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for treating chronic bronchitis provided according to the understanding mechanism of Chinese traditional treatment chronic bronchitis, each component and its mass parts ratio of the medicine are as follows:250~600g of the Japanese ardisia, 250~960g of berchemia lineata, 100~160g of chrysanthemum, 150~280g of cordate houttuynia, 25~120g of Chinese ephedra, 100~300g of purple perilla, 30~70g of peppermint, 250~550g of beautiful millettia root, 50~100g of almond, 200~250g of arrowleaf abelmoschus root, 60~180g of asparagus fern, 90~160g of Snakegourd Fruit, 60~150g of the tuber of dwarf lilyturf, 100~260g of wheat dry measure used in former times, 100~160g of selfheal;Medicine provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating chronic bronchitis, especially
It is the field of the capsule medicine used for chronic bronchitis patient and preparation method thereof.
Background technology
Shown according to documents and materials:Chronic bronchitis, chronic bronchitis are trachea-bronchial epithelial cell mucous membrane and surrounding tissue
Chronic nonspecific inflammation.Clinic is to cough, expectoration as cardinal symptom, annual morbidity continues three months, continuous 2 years or 2 years
More than.Need further to exclude with cough, expectoration, the other diseases of wheezing symptoms(Such as pulmonary tuberculosis, pneumoconiosis, pulmonary abscess, heart
The illness such as disease, cardiac insufficiency, bronchiectasis, bronchial astehma, chronic nasopharyngitis, esophageal reflux syndrome).
Clinical manifestation:
Slow onset, course of disease length, repeatedly acute attack and aggravation.Cardinal symptom is cough, expectoration, or with panting.It is anxious
Property aggravate mean cough, expectoration, pant etc. that symptom aggravates suddenly.The main reason for acute exacerbation is respiratory tract infection, pathogen
Can be virus, bacterium, mycoplasma and Chlamydia etc..
A. cough
There are paroxysmal cough or expectoration based on typically coughing with daystart, during sleep.
B. expectoration
Generally white mucus and slurries spumescence, occasionally can be with blood.Early morning expectoration is more, and after getting up or position variation can the row of stimulation
Phlegm.
C. pant or out of breath
The obvious person that pants is frequently referred to asthmatic bronchitis, may partly close with bronchial astehma.If it can be showed during with pulmonary emphysema
To be out of breath after work or activity.More absence of signs in early days.Acute attack stage can hear dry, moist rales at back or double bases of lung,
It can reduce or disappear after cough.Such as merge asthma audible and extensive wheezing sound and extend with the expiration phase.
So, it is those skilled in the art with regard to how to find a kind of Chinese medicine composition for imitating treatment chronic bronchitis
The problem of urgently to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment chronic bronchitis, during people gradually appreciate
Cure the advantages for the treatment of chronic bronchitis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing
There is the present situation of western medical treatment chronic bronchitis, the purpose of the present invention is to be to provide a kind of capsule for treating chronic bronchitis
Agent medicine, to solve the problems, such as that chronic bronchitis patient is got well early.The medicine is using common Chinese medicine as raw material, is led to
Cross and select rational medicine and mass parts ratio, can effectively treat above-mentioned chronic bronchitis.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:One kind is provided and treats chronic bronchial
Scorching capsule medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
250~600g of the Japanese ardisia, 250~960g of berchemia lineata, 100~160g of chrysanthemum, 150~280g of cordate houttuynia, Chinese ephedra 25~
120g, 100~300g of purple perilla, 30~70g of peppermint, 250~550g of beautiful millettia root, 50~100g of almond, arrowleaf abelmoschus root 200~
250g, 60~180g of asparagus fern, 90~160g of Snakegourd Fruit, 60~150g of the tuber of dwarf lilyturf, 100~260g of wheat dry measure used in former times, 100~160g of selfheal.
A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that the medicine it is each
Individual component and its mass parts are than as follows:
280~510g of the Japanese ardisia, 280~830g of berchemia lineata, 115~140g of chrysanthemum, 180~250g of cordate houttuynia, Chinese ephedra 30~
105g, 115~260g of purple perilla, 36~60g of peppermint, 280~480g of beautiful millettia root, 58~90g of almond, 220~240g of arrowleaf abelmoschus root,
70~150g of asparagus fern, 100~140g of Snakegourd Fruit, 70~130g of the tuber of dwarf lilyturf, 115~230g of wheat dry measure used in former times, 115~140g of selfheal.
A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that " the optimal side
The each component and its mass parts of the medicine of case " are than as follows:
Japanese ardisia 430g, berchemia lineata 710g, chrysanthemum 120g, cordate houttuynia 220g, Chinese ephedra 95g, purple perilla 230g, peppermint 50g, beautiful millettia root
420g, almond 80g, arrowleaf abelmoschus root 210g, asparagus fern 130g, Snakegourd Fruit 120g, tuber of dwarf lilyturf 115g, wheat dry measure used in former times 200g, selfheal 120g.
A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that methods described includes
Following steps are prepared:
A, after above-mentioned raw materials Chinese medicine being picked impurity, dust and dried, it is stand-by to be ground into superfine end according to mass parts ratio;
B, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, ground superfine myrrh thing is sieved
Afterwards, it is put into medicine device and is well mixed in the lump with auxiliary material, is then prepared into capsule(Total length is 23.3mm after its capsule is sealed,
Medicinal powder capacity 0.4~0.5g/ grains), then sterilize, dispense, sealing.
A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that the instructions of taking
For:By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 3.5g/ times, warm water is sent
Clothes.One week was a course for the treatment of, and after 3~6 courses for the treatment of of taking medicine, symptom gradually mitigates or fully recovered.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
The Japanese ardisia, nature and flavor:It is pungent, flat, have relieving cough and reducing sputum, wind-dispelling removing toxic substances, promoting blood circulation and stopping pain the effect of, for treat bronchitis,
Lobar pneumonia, infantile pneumonia, pulmonary tuberculosis, hepatitis, dysentery, acute nephritis, urinary tract infections, stimulate the menstrual flow, traumatic injury, rheumatism muscles and bones
Bitterly, the diseases such as skin itching, dermatitis rhus are controlled in external application;
Berchemia lineata, nature and flavor:It is slight bitter, puckery, flat, there is the effect of removing blood stasis and hemostasis, antibechic analgesic, for treating hemoptysis of pulmonary tuberculosis, stomach,
Duodenal ulcer and hemorrhage, schizophrenia, traumatic injury, treating rheumatic ostealgia, furunculosis furuncle, enlarged lymph nodes of neck, testiclar gall;
Chrysanthemum, nature and flavor:Sweet, bitter, cold nature, there is the effect of wind and heat dispersing, flat liver improving eyesight, removing toxicity for detumescence, it is outer for treating
Feel wind or wind-warm syndrome from the beginning of, fever and headache, dizziness, red eye, swell pain, furuncle swelling toxin;
Cordate houttuynia, nature and flavor:It is pungent, be slightly cold, have the clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia the effect of, told for treating lung carbuncle
Purulence, phlegm heat panting cough, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus;
Chinese ephedra, nature and flavor:It is pungent, slight bitter, warm-natured, have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of, for treating chill
Superficies excess syndrome, fever with aversion to cold, it is lossless, headache body pain,;Heresy is stopped up in lung, Lung Qi obstruction, cough and asthma, edema caused by wind, difficult urination, wind
Arthritis with fixed pain caused by dampness pain, skin numbness and rubella itch, cloudy subcutaneous ulcer subcutaneous nodule;
Purple perilla, nature and flavor:It is acrid flavour, cool in nature, have deliver facilitaing lung, it is clearing heat and detoxicating the effect of, for treating anemopyretic cold, the hot cough in high mountain
Cough, abscess of throat, sore furuncle poison;
Peppermint, nature and flavor:It is acrid flavour, cool in nature, there is the effect of dissipate wind-heat, refresh oneself, throat, promoting eruption, strongly fragrant solution, for treating wind-heat
The diseases such as exterior syndrome, headache and hot eyes, abscess of throat, measles without adequate eruption, sunken rash itch, liver-depressed hypochondrium pain;
Beautiful millettia root, nature and flavor:It is sweet, flat, there is qi-restoratives moistening lung, the effect of strengthening tendons is active, for treating lumbar muscle strain, rheumatism joint
Inflammation, control the diseases such as lung heat, cough due to deficiency of the lung, pulmonary tuberculosis, chronic bronchitis, chronic hepatitis, seminal emission, leukorrhea;
Almond, nature and flavor:Bitter, tepor, it is slightly poisonous, there is the effect of sending down abnormally ascending is relieving cough and asthma, relaxes bowel, for treating gas of coughing
Asthma, fullness sensation in chest abundant expectoration, deficiency of blood Tianjin are withered, dry constipation of intestines;
Arrowleaf abelmoschus root, nature and flavor:Micro-sweet, put down, there is the effect of nourishing Yin and clearing heat, apocenosis are drawn out pus by applying a plaster to the affected part, for treating pulmonary tuberculosis, dryness of the lung cough
Cough, puerperal constipation, neurasthenia, the diseases such as ulcerative carbuncle pyogenic infections are controlled in external application;
Asparagus fern, nature and flavor:It is sweet, bitter, cold, have nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire the effect of, for treat dryness of the lung dry cough, cough due to consumptive disease,
Injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, diphtheria, internal heat anticance, plies and phlegm, nourishing Yin and moistening dryness;
Snakegourd Fruit, nature and flavor:Sweet, slight bitter, tremble with fear, there is the effect of clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation, for treating lung heat cough
Cough, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swell and ache, constipation;
The tuber of dwarf lilyturf, nature and flavor:Sweet, slight bitter, it is slightly cold, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease
The diseases such as cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria;
Wheat dry measure used in former times, nature and flavor:It is sweet, light, cool, there is the effect of nourishing Yin and clearing heat, preventing phlegm from forming and stopping coughing, for treating xeropulmonary cough, pulmonary tuberculosis is coughed up
Blood, pyreticosis polydipsia, tonsillitis;
Selfheal, nature and flavor:It is pungent, bitter, cold, have relieve inflammation or internal heat, improving eyesight, dissipating bind, detumescence the effect of, for treating red eye, swell pain, mesh pearl
The diseases such as nyctalgia, dizziness of having a headache, scrofula, goiter and tumor, acute mastitis swelling and pain, Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension.
Medicine of the present invention is the principle based on Chinese traditional treatment chronic bronchitis, from the pathology machine according to chronic bronchitis
System and pharmacological action are thought:With regard to chronic bronchitis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, to upper
Stating disease has good therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned chronic bronchitis, using the formula system
Standby medicine effect is good, quick, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to this hair
Bright embodiment is described in further detail:
Embodiment 1:
A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine
Than as follows:
Japanese ardisia 430g, berchemia lineata 710g, chrysanthemum 120g, cordate houttuynia 220g, Chinese ephedra 95g, purple perilla 230g, peppermint 50g, beautiful millettia root
420g, almond 80g, arrowleaf abelmoschus root 210g, asparagus fern 130g, Snakegourd Fruit 120g, tuber of dwarf lilyturf 115g, wheat dry measure used in former times 200g, selfheal 120g.
Embodiment 2:
A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine
Than as follows:
Japanese ardisia 510g, berchemia lineata 830g, chrysanthemum 140g, cordate houttuynia 250g, Chinese ephedra 105g, purple perilla 260g, peppermint 60g, Niu great
Power 480g, almond 90g, arrowleaf abelmoschus root 240g, asparagus fern 150g, Snakegourd Fruit 140g, tuber of dwarf lilyturf 130g, wheat dry measure used in former times 230g, selfheal 140g.
Embodiment 3:
A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine
Than as follows:
Japanese ardisia 600g, berchemia lineata 960g, chrysanthemum 160g, cordate houttuynia 280g, Chinese ephedra 120g, purple perilla 300g, peppermint 70g, Niu great
Power 550g, almond 100g, arrowleaf abelmoschus root 250g, asparagus fern 180g, Snakegourd Fruit 160g, tuber of dwarf lilyturf 150g, wheat dry measure used in former times 260g, selfheal 160g.
Model case
Through clinical conditions chronic bronchitis patient totally 1100, the age is 600 of more than 38 years old, and only 500 are
Less than 38 years old.790 to be fully recovered in 1100 patients, effective 200, invalid 110.Total effective rate is up to 90%.
Claims (3)
1. a kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its quality of the medicine
Part is than as follows:
250~600g of the Japanese ardisia, 250~960g of berchemia lineata, 100~160g of chrysanthemum, 150~280g of cordate houttuynia, Chinese ephedra 25~
120g, 100~300g of purple perilla, 30~70g of peppermint, 250~550g of beautiful millettia root, 50~100g of almond, arrowleaf abelmoschus root 200~
250g, 60~180g of asparagus fern, 90~160g of Snakegourd Fruit, 60~150g of the tuber of dwarf lilyturf, 100~260g of wheat dry measure used in former times, 100~160g of selfheal.
2. it is according to claim 1 treatment chronic bronchitis capsule medicine, it is characterised in that the medicine it is each
Individual component and its mass parts are than as follows:
280~510g of the Japanese ardisia, 280~830g of berchemia lineata, 115~140g of chrysanthemum, 180~250g of cordate houttuynia, Chinese ephedra 30~
105g, 115~260g of purple perilla, 36~60g of peppermint, 280~480g of beautiful millettia root, 58~90g of almond, 220~240g of arrowleaf abelmoschus root,
70~150g of asparagus fern, 100~140g of Snakegourd Fruit, 70~130g of the tuber of dwarf lilyturf, 115~230g of wheat dry measure used in former times, 115~140g of selfheal.
3. the capsule medicine of the treatment chronic bronchitis according to claim 1 to 2, it is characterised in that the medicine
Each component and its mass parts than as follows:
Japanese ardisia 430g, berchemia lineata 710g, chrysanthemum 120g, cordate houttuynia 220g, Chinese ephedra 95g, purple perilla 230g, peppermint 50g, beautiful millettia root
420g, almond 80g, arrowleaf abelmoschus root 210g, asparagus fern 130g, Snakegourd Fruit 120g, tuber of dwarf lilyturf 115g, wheat dry measure used in former times 200g, selfheal 120g.
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CN201710652122.2A CN107375706A (en) | 2017-08-02 | 2017-08-02 | A kind of capsule medicine for treating chronic bronchitis and preparation method thereof |
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CN201710652122.2A CN107375706A (en) | 2017-08-02 | 2017-08-02 | A kind of capsule medicine for treating chronic bronchitis and preparation method thereof |
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