CN107349368A - A kind of capsule medicine for treating chronic bronchitis and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for treating chronic bronchitis provided according to the understanding mechanism of Chinese traditional treatment chronic bronchitis, each component and its mass parts ratio of the medicine are as follows：250~1000g of berchemia lineata, 150~260g of cordate houttuynia, 250~550g of the Japanese ardisia, 80~120g of Chinese ephedra, 100~320g of purple perilla, 80~160g of chrysanthemum, 30~80g of peppermint, 300~650g of beautiful millettia root, 30~90g of the tuber of stemona, 200~260g of arrowleaf abelmoschus root, 60~160g of asparagus fern, 150~260g of the capsule of weeping forsythia, the tuber of dwarf lilyturf（Remove the heart）60~160g, 100~260g of wheat dry measure used in former times, 250~300g of the Radix Astragali etc.；Medicine provided by the invention is a Chinese prescription treated both principal and secondary aspect of disease.

Description

A kind of capsule medicine for treating chronic bronchitis and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating chronic bronchitis, especially It is the field of the capsule medicine used for chronic bronchitis patient and preparation method thereof.

Background technology

Doctor thinks：Chronic bronchitis is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucous membrane and surrounding tissue.Face Bed is to cough, expectoration as cardinal symptom, annual morbidity continues 3 months, continuous 2 years or more than 2 years.Need further to exclude to have Cough, expectoration, the other diseases of wheezing symptoms（As pulmonary tuberculosis, pneumoconiosis, pulmonary abscess, heart disease, cardiac insufficiency, bronchus expand , bronchial astehma, chronic nasopharyngitis, the illness such as esophageal reflux syndrome）.

Clinical manifestation：

Slow onset, course of disease length, repeatedly acute attack and aggravation.Cardinal symptom is cough, expectoration, or with panting.It is anxious Property aggravate mean cough, expectoration, pant etc. that symptom aggravates suddenly.The main reason for acute exacerbation is respiratory tract infection, pathogen Can be virus, bacterium, mycoplasma and Chlamydia etc..

A. cough

There are paroxysmal cough or expectoration based on general daystart cough, during sleep.

B. expectoration

Generally white mucus and slurries spumescence, occasionally can be with blood.Early morning expectoration is more, and after getting up or position variation can the row of stimulation Phlegm.

C. pant or out of breath

The obvious person that pants is frequently referred to asthmatic bronchitis, may partly close with bronchial astehma.If it can be showed during with pulmonary emphysema To be out of breath after work or activity.

More absence of signs in early days.Acute attack stage can hear dry, moist rales at back or double bases of lung, can be reduced after cough Or disappear.Such as merge asthma audible and extensive wheezing sound and extend with the expiration phase.

So, it is people in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat chronic bronchitis The problem of member is urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment chronic bronchitis, during people gradually appreciate Cure the advantages for the treatment of chronic bronchitis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing There is the present situation of western medical treatment chronic bronchitis, the purpose of the present invention is to be to provide a kind of capsule for treating chronic bronchitis Agent medicine, to solve the problems, such as that chronic bronchitis patient is got well early.The medicine is using common Chinese medicine as raw material, is led to Cross and select rational medicine and mass parts ratio, can effectively treat above-mentioned chronic bronchitis.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats chronic bronchial Scorching capsule medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

250~1000g of berchemia lineata, 150~260g of cordate houttuynia, 250~550g of the Japanese ardisia, 80~120g of Chinese ephedra, purple perilla 100~ 320g, 80~160g of chrysanthemum, 30~80g of peppermint, 300~650g of beautiful millettia root, 30~90g of the tuber of stemona, 200~260g of arrowleaf abelmoschus root, 60~160g of asparagus fern, 150~260g of the capsule of weeping forsythia, the tuber of dwarf lilyturf（Remove the heart）60~160g, 100~260g of wheat dry measure used in former times, 250~300g of the Radix Astragali.

A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

290~850g of berchemia lineata, 170~230g of cordate houttuynia, 280~480g of the Japanese ardisia, 90~105g of Chinese ephedra, purple perilla 115~ 280g, 90~140g of chrysanthemum, 40~70g of peppermint, 260~560g of beautiful millettia root, 40~80g of the tuber of stemona, 230~250g of arrowleaf abelmoschus root, 70~140g of asparagus fern, 170~230g of the capsule of weeping forsythia, the tuber of dwarf lilyturf（Remove the heart）70~140g, 115~230g of wheat dry measure used in former times, 270~260g of the Radix Astragali.

A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that " the optimal side The each component and its mass parts of the medicine of case " are than as follows：

Berchemia lineata 720g, cordate houttuynia 200g, Japanese ardisia 420g, Chinese ephedra 90g, purple perilla 250g, chrysanthemum 120g, peppermint 60g, beautiful millettia root 500g, tuber of stemona 70g, arrowleaf abelmoschus root 240g, asparagus fern 120g, capsule of weeping forsythia 200g, the tuber of dwarf lilyturf（Remove the heart）120g, wheat dry measure used in former times 200g, Radix Astragali 230g.

A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that methods described includes Following steps are prepared：

A. 1. medicinal alcohol reflux extraction is secondary in above-mentioned all raw materials, and each concentration of alcohol is respectively：80%th, 60%, each second Alcohol dosage is respectively：10 times, 8 times of amounts, extraction time is respectively：180 min, 120min, leaching decoction；2. merge extract solution, The medicinal extract that relative density is 1.10 when filtrate is concentrated into 80 DEG C is stand-by；

B. the method for preparing Chinese medicine capsules according to tradition, will add auxiliary material in the above-mentioned medicinal extract prepared：Appropriate starch, second Appropriate alcohol, appropriate dextrin, Magnesium Stearate proper quantity, are then prepared into capsule（Total length is 23.3mm after its capsule is sealed, medicinal powder Capacity 0.4~0.5g/ grains）, sealed packaging.

A kind of capsule medicine for treating chronic bronchitis and preparation method thereof, it is characterised in that the instructions of taking For：By the capsule prepared twice a day to take, once a dose sooner or later, and dosage 2g/time, warm water is sent down（Divide the age Size is administered, and 1 years old 0.4g/time；2 years old to 3 years old 0.8g/time；4 years old to 7 years old 1.2g/time；8 years old to 14 years old 1.6/ time；Adult 2/ It is secondary）.7 days are a course for the treatment of, and after 1~3 course for the treatment of of taking medicine, symptom fades away, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Berchemia lineata, nature and flavor：It is slight bitter, puckery, flat, there is the effect of removing blood stasis and hemostasis, antibechic analgesic, for treating hemoptysis of pulmonary tuberculosis, stomach Duodenal ulcer and hemorrhage, schizophrenia, traumatic injury, treating rheumatic ostealgia, furunculosis furuncle, enlarged lymph nodes of neck, testiclar gall；

Cordate houttuynia, nature and flavor：It is pungent, be slightly cold, have the clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia the effect of, told for treating lung carbuncle Purulence, phlegm heat panting cough, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus；

The Japanese ardisia, nature and flavor：It is pungent, flat, have relieving cough and reducing sputum, wind-dispelling removing toxic substances, promoting blood circulation and stopping pain the effect of, for treat bronchitis, Lobar pneumonia, infantile pneumonia, pulmonary tuberculosis, hepatitis, dysentery, acute nephritis, urinary tract infections, stimulate the menstrual flow, traumatic injury, rheumatism muscles and bones Bitterly, skin itching, dermatitis rhus are controlled in external application；

Chinese ephedra, nature and flavor：It is pungent, slight bitter, warm-natured, have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of, for treating chill Superficies excess syndrome, fever with aversion to cold, it is lossless, headache body pain,；Heresy is stopped up in lung, Lung Qi obstruction, cough and asthma, edema caused by wind, difficult urination, wind Arthritis with fixed pain caused by dampness pain, skin numbness and rubella itch, cloudy subcutaneous ulcer subcutaneous nodule；

Purple perilla, nature and flavor：It is acrid flavour, cool in nature, have deliver facilitaing lung, it is clearing heat and detoxicating the effect of, for treating anemopyretic cold, the hot cough in high mountain Cough, abscess of throat, sore furuncle poison；

Chrysanthemum, nature and flavor：Sweet, bitter, cold nature, there is the effect of wind and heat dispersing, flat liver improving eyesight, removing toxicity for detumescence, it is outer for treating Feel wind or wind-warm syndrome from the beginning of, fever and headache, dizziness, red eye, swell pain, furuncle swelling toxin；

Peppermint, nature and flavor：It is acrid flavour, cool in nature, there is dispelling wind, radiate, ward off the effect of dirty, removing toxic substances, for treat affection of exogenous wind-heat, headache, The diseases such as hot eyes, abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria；

Beautiful millettia root, nature and flavor：It is sweet, flat, there is qi-restoratives moistening lung, the effect of strengthening tendons is active, for treating lumbar muscle strain, rheumatism joint Inflammation, control the diseases such as lung heat, cough due to deficiency of the lung, pulmonary tuberculosis, chronic bronchitis, chronic hepatitis, seminal emission, leukorrhea；

The tuber of stemona, nature and flavor：Sweet, bitter, tepor, it is slightly poisonous, there is the effect of moistening lung to lower qi cough-relieving, desinsection, coughed for treating new chronic cough, Pulmonary tuberculosis cough, pertussis, moistened the lung and relieve the cough outside for head louse, body louse, enterobiasis, pruritus vulvae, the sweet tuber of stemona, for deficiency of Yin overstrain cough；

Arrowleaf abelmoschus root, nature and flavor：Micro-sweet, put down, there is the effect of nourishing Yin and clearing heat, apocenosis are drawn out pus by applying a plaster to the affected part, for treating pulmonary tuberculosis, dryness of the lung cough Cough, puerperal constipation, neurasthenia, the diseases such as ulcerative carbuncle pyogenic infections are controlled in external application；

Asparagus fern, nature and flavor：It is sweet, bitter, cold, have nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire the effect of, for treat dryness of the lung dry cough, cough due to consumptive disease, Injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, diphtheria, internal heat anticance, plies and phlegm, nourishing Yin and moistening dryness；

The capsule of weeping forsythia, nature and flavor：Bitter, cold nature, there is the effect of clearing heat and detoxicating, dispersing swelling and dissipating binds, anemopyretic cold, for treating wind-heat sense Emit, the disease such as warm disease, heat gonorrhea renal shutdown, ulcer, pyogenic infections, scrofula, goiter and tumor, larynx numbness；

The tuber of dwarf lilyturf（Remove the heart）, nature and flavor：Sweet, slight bitter is slightly cold, and has the effect of Yin nourishing and lung moistening, beneficial stomach clear away heart-fire, for the lung-dryness syndrome due to yin deficiency, dry cough Phlegm is thick, overstrain cough spitting of blood, the few thirsty, vexed insomnia in Tianjin, dry constipation of intestines；

Wheat dry measure used in former times, nature and flavor：It is sweet, light, cool, there is the effect of nourishing Yin and clearing heat, preventing phlegm from forming and stopping coughing, for treating xeropulmonary cough, pulmonary tuberculosis is coughed up Blood, pyreticosis polydipsia, tonsillitis；

The Radix Astragali, nature and flavor：Sweet, tepor, there is the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, Flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes etc..

Medicine of the present invention is the principle based on Chinese traditional treatment chronic bronchitis, from the pathology machine according to chronic bronchitis System and pharmacological action are thought：With regard to chronic bronchitis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, to upper Stating disease has good therapeutic effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned chronic bronchitis, using the formula system Standby medicine effect is good, quick, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to this hair Bright embodiment is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine Than as follows：

Berchemia lineata 720g, cordate houttuynia 200g, Japanese ardisia 420g, Chinese ephedra 90g, purple perilla 250g, chrysanthemum 120g, peppermint 60g, beautiful millettia root 500g, tuber of stemona 70g, arrowleaf abelmoschus root 240g, asparagus fern 120g, capsule of weeping forsythia 200g, the tuber of dwarf lilyturf（Remove the heart）120g, wheat dry measure used in former times 200g, Radix Astragali 230g.

Embodiment 2：

A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine Than as follows：

Berchemia lineata 850g, cordate houttuynia 230g, Japanese ardisia 480g, Chinese ephedra 105g, purple perilla 280g, chrysanthemum 140g, peppermint 70g, Niu great Power 560g, tuber of stemona 80g, arrowleaf abelmoschus root 250g, asparagus fern 140g, capsule of weeping forsythia 230g, the tuber of dwarf lilyturf（Remove the heart）140g, wheat dry measure used in former times 230g, the Radix Astragali 260g。

Embodiment 3：

A kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its mass parts of the medicine Than as follows：

Berchemia lineata 1000g, cordate houttuynia 260g, Japanese ardisia 550g, Chinese ephedra 120g, purple perilla 320g, chrysanthemum 160g, peppermint 80g, Niu great Power 650g, tuber of stemona 90g, arrowleaf abelmoschus root 260g, asparagus fern 160g, capsule of weeping forsythia 260g, the tuber of dwarf lilyturf（Remove the heart）160g, wheat dry measure used in former times 260g, the Radix Astragali 300g。

Model case

Through clinical conditions chronic bronchitis patient totally 1840, the age is 975 of more than 16 years old, and only 865 are Less than 16 years old.1755 to be fully recovered in 1840 patients, effective 85, total effective rate is up to 100%.

Claims (3)

1. a kind of capsule medicine for treating chronic bronchitis, it is characterised in that each component and its quality of the medicine Part is than as follows：

250~1000g of berchemia lineata, 150~260g of cordate houttuynia, 250~550g of the Japanese ardisia, 80~120g of Chinese ephedra, purple perilla 100~ 320g, 80~160g of chrysanthemum, 30~80g of peppermint, 300~650g of beautiful millettia root, 30~90g of the tuber of stemona, 200~260g of arrowleaf abelmoschus root, 60~160g of asparagus fern, 150~260g of the capsule of weeping forsythia, the tuber of dwarf lilyturf（Remove the heart）60~160g, 100~260g of wheat dry measure used in former times, 250~300g of the Radix Astragali.

2. it is according to claim 1 treatment chronic bronchitis capsule medicine, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

290~850g of berchemia lineata, 170~230g of cordate houttuynia, 280~480g of the Japanese ardisia, 90~105g of Chinese ephedra, purple perilla 115~ 280g, 90~140g of chrysanthemum, 40~70g of peppermint, 260~560g of beautiful millettia root, 40~80g of the tuber of stemona, 230~250g of arrowleaf abelmoschus root, 70~140g of asparagus fern, 170~230g of the capsule of weeping forsythia, the tuber of dwarf lilyturf（Remove the heart）70~140g, 115~230g of wheat dry measure used in former times, 270~260g of the Radix Astragali.

3. the capsule medicine of the treatment chronic bronchitis according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts than as follows：

Berchemia lineata 720g, cordate houttuynia 200g, Japanese ardisia 420g, Chinese ephedra 90g, purple perilla 250g, chrysanthemum 120g, peppermint 60g, beautiful millettia root 500g, tuber of stemona 70g, arrowleaf abelmoschus root 240g, asparagus fern 120g, capsule of weeping forsythia 200g, the tuber of dwarf lilyturf（Remove the heart）120g, wheat dry measure used in former times 200g, Radix Astragali 230g.