CN107375586A - A kind of Chinese medicinal film for surface anesthesia and preparation method thereof - Google Patents

A kind of Chinese medicinal film for surface anesthesia and preparation method thereof Download PDF

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CN107375586A
CN107375586A CN201710570056.4A CN201710570056A CN107375586A CN 107375586 A CN107375586 A CN 107375586A CN 201710570056 A CN201710570056 A CN 201710570056A CN 107375586 A CN107375586 A CN 107375586A
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parts
chinese
radix
surface anesthesia
chinese medicinal
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付鑫
梁枫
韩方雷
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Jilin University
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Jilin University
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention provides a kind of Chinese medicinal film for surface anesthesia and preparation method thereof, is related to technical field of traditional Chinese medicines, includes the constituent of following parts by weight：8 18 parts of 60 75 parts of Chinese azalea, 50 60 parts of The Iron Buddha, 30 48 parts of datura flower, 10 18 parts of radix aconiti agrestis, 25 40 parts of the Radix Astragali, 25 36 parts of Radix Angelicae Sinensis, 15 24 parts of dried pinellia, 20 35 parts of arisacma consanguineum schott, 30 40 parts of rhizoma typhonii, 28 40 parts of Chinese prickly ash, 15 30 parts of arabian jasmine root, 22 30 parts of pseudo-ginseng, 10 20 parts of calamus, 5 15 parts of borneol, 10 25 parts of radix glycyrrhizae and peppermint, medicinal material compatibility is suitable selected by the present invention, bring out the best in each other, drug effect penetrability is strong, rapid-action, anesthesia duration is long, safe ready, has no side effect.

Description

A kind of Chinese medicinal film for surface anesthesia and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicinal film for surface anesthesia and preparation method thereof.
Background technology
Relevant anaesthesia technology, the earliest literature record in the world occur from the Han dynasty in China, by the famous surgery of ancient Chinese Expert, the fiber crops boiling soup of traditional Chinese medicine scholar Huatuo doctor invention.Fiber crops boiling soup is traditional Chinese herbal decoction equivalent to present oral general anesthesia agent, mouth The dermal sensation of patient's loss of consciousness is lost and operation convenient to carry out after clothes.Fiber crops boiling soup belongs to the most leading drug anesthesia skill in the world at that time Art.But because of the remote past and year-by-year wars stream is in lost.Later doctor trained in Western medicine has invented various anesthetic, such as profit now prevailing More cacaines, Bupivacaine, procaine etc., medicine must be noted with syringe if the surface anesthesia of local skin to be implemented Inject it is intracutaneous can just play anaesthetic effect, this anesthesia method operation is comparatively laborious, while also has certain risk.In addition anaesthetize Containing hormone and artificial synthesized medicament in product form composition mostly, long-term use can bring different degrees of harm to human body, Extend the state of an illness and add convalescence.And anesthesia duration is long, effect is poor, costly.Therefore, we are badly in need of developing a kind of middle drug anesthesia Fish pickled by wine is preferably to implement local surfaces anesthesia.
The content of the invention
(1) technical problem solved
In view of the shortcomings of the prior art, the invention provides a kind of Chinese medicinal film for surface anesthesia and preparation method thereof, With the advantages of penetrability is strong, rapid-action, anesthesia duration is long, safe ready.
(2) technical scheme
To realize object above, the present invention is achieved by the following technical programs：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：Chinese azalea 60-75 parts, iron sieve Chinese 50-60 parts, datura flower 30-48 parts, radix aconiti agrestis 10-18 parts, Radix Astragali 25-40 parts, Radix Angelicae Sinensis 25-36 parts, dried pinellia 15-24 parts, life Southern Star 20-35 parts, rhizoma typhonii 30-40 parts, Chinese prickly ash 28-40 parts, arabian jasmine root 15-30 parts, pseudo-ginseng 22-30 parts, calamus 10-20 parts, Borneol 5-15 parts, radix glycyrrhizae 10-25 parts and peppermint 8-18 parts.
Further, the above-mentioned Chinese medicinal film for surface anesthesia, the constituent of following parts by weight is included：Chinese azalea 65- 70 parts, The Iron Buddha 52-56 parts, datura flower 40-45 parts, radix aconiti agrestis 12-16 parts, Radix Astragali 30-36 parts, Radix Angelicae Sinensis 28-32 parts, dried pinellia 17-22 parts, arisacma consanguineum schott 23-30 parts, rhizoma typhonii 34-37 parts, Chinese prickly ash 30-37 parts, arabian jasmine root 20-28 parts, pseudo-ginseng 25-27 parts, Chang Pu 13-18 parts, borneol 7-12 parts, radix glycyrrhizae 16-22 parts and peppermint 10-14 parts.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in ethanol, after soak at room temperature 2h, are warming up to 40-50 DEG C, ultrasonic extraction 40-60min, then room temperature is naturally cooled to, filter, filtrate is concentrated to give thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 20-50 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Further, the weight of ethanol is the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in the step (1) 30-50 times of amount.
Further, the concentration of ethanol is 75% in the step (1).
Further, the frequency in the step (1) during ultrasonic extraction is 500-700W.
Further, controlled when being coated in the step (3) per 1cm2Face paper on be coated with 0.5-1.2g anesthesia Ointment body.
In the present invention, herbal nature used is as follows：
Chinese azalea：Pungent, temperature is very toxic.Dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, analgesia analgesic.For rheumatoid arthritis stubborn, fracture pain, tooth Bitterly, skin stubborn dermatitis.
The Iron Buddha：It is pungent, temperature.It is very toxic.Dispelling wind and eliminating dampness is cured mainly, promoting blood circulation and removing obstruction in channels, analgesic.Available for local anaesthesia, rheumatism fiber crops Wood, lumbocrural pain, joint sprain.
Datura flower：It is warm-natured；It is poisonous.Relieving cough and asthma, analgesic is calm.Asthma and cough, coldness and pain in the epigastrium, arthralgia pain due to rheumatism, children are slow It is frightened；Surgical anesthesia.
Radix aconiti agrestis：Acrid flavour, hardship, property heat.Available for wind-cold-dampness arthralgia, arthralgia, trusted subordinate's crymodynia, cold hernia, which is had a pain and anaesthetized, stops Bitterly.
The Radix Astragali：It is sweet, slightly warm in nature.There are invigorating qi for consolidating superficies, arrest sweating admittedly take off, torr sore myogenic, inducing diuresis for removing edema.
Radix Angelicae Sinensis：It is sweet, pungent, warm.Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Disease Lump in the abdomen knot gathers；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Dried pinellia：It is pungent, temperature.It is poisonous.It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass；Externally used detumescence relieves pain.
Arisacma consanguineum schott：It is bitter, pungent, temperature；It is poisonous.It is eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.It is dizzy for stupid productive cough, wind phlegm It is dizzy, heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, epilepsy, infantile convulsion, lockjaw.Life controlling outward carbuncle swells, snake bite and insect sting.
Rhizoma typhonii：Acrid flavour, it is warm-natured.Wind-dispelling phlegm, arresting convulsion are jerked, detoxicating and resolving a mass, analgesic.Cure mainly and be used for heap soil or fertilizer over and around the roots of apoplexy phlegm, mouth eye is sung Tiltedly, dysphasia, infantile convulsion epilepsy, lockjaw, phlegm and headache, migraine and general headache, scrofula subcutaneous nodule, venomous snake bite.
Chinese prickly ash：Acrid flavour, it is warm-natured.Warm in pain, desinsection are antipruritic.Cure mainly and be used for coldness and pain in the epigastrium, vomiting and diarrhea, abdominal pain due to enterositosis； External application：Eczema, pruritus vulvae.
Arabian jasmine root：Bitter, property heat.Anesthesia, analgesic.Cure mainly and be used for traumatic injury and carious tooth pain, also control headache, have a sleepless night.
Pseudo-ginseng：Sweet, slight bitter, temperature.Dissipate stasis of blood hemostasis, detumescence ding-tong.Cure mainly for spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, outside Hinder bleeding, chest and abdomen shouting pain, tumbling and swelling.
Calamus：It is bitter, pungent, temperature.Resolving sputum, have one's ideas straightened out, invigorating the spleen, dampness removing.For epilepsy, palpitation with fear is forgetful, clouded in mind, humidity hysteresis ruffian It is swollen, dysentery, rheumatalgia pain, carbuncle swells scabies.
Borneol：Acrid flavour, hardship, are slightly cold；Delicate fragrance a surname dissipate, has an inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, the effect of removing nebula, cures mainly High fever apoplexy coma due to blocking of the respiratory system shies epilepsy, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, throat deafness, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid.
Radix glycyrrhizae：It is sweet, it is mild-natured.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For taste Weakness, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Peppermint：Acrid flavour, it is cool in nature.Dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi.Affection of exogenous wind-heat is cured mainly, is had a headache, Abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria, warm disease is from the beginning of, rubella itch, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.
(3) beneficial effect
The invention provides a kind of Chinese medicinal film for surface anesthesia and preparation method thereof, medicinal material compatibility phase selected by the present invention Preferably, bring out the best in each other, drug effect penetrability is strong, rapid-action, anesthesia duration is long, safe ready, has no side effect, but also has heat-clearing solution Poison, narcotic analgesic, hemostasia and promoting granulation, anti-inflammation detumescence, nourishing blood and tranquilization, qi-regulating and in and other effects, preparation method is simple, the production cycle It is short and cheap, it is adapted to large-scale promotion.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention, Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one Divide embodiment, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not making The every other embodiment obtained under the premise of creative work, belongs to the scope of protection of the invention.
Embodiment 1：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：65 parts of Chinese azalea, The Iron Buddha 52 Part, 40 parts of datura flower, 12 parts of radix aconiti agrestis, 30 parts of the Radix Astragali, 28 parts of Radix Angelicae Sinensis, 17 parts of dried pinellia, 23 parts of arisacma consanguineum schott, 34 parts of rhizoma typhonii, flower 10 parts of 30 parts of green pepper, 20 parts of arabian jasmine root, 25 parts of pseudo-ginseng, 13 parts of calamus, 7 parts of borneol, 16 parts of radix glycyrrhizae and peppermint.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in the ethanol that concentration is 75%, after soak at room temperature 2h, It is warming up to 45 DEG C, ultrasonic extraction 45min, frequency during ultrasonic extraction is 600W, then naturally cools to room temperature, is filtered, filtrate is dense Contracting obtains thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 40 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Wherein, the weight of ethanol is 40 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in step (1).
Wherein, controlled when being coated in step (3) per 1cm2Face paper on be coated with 1g arcotic lotion.
Embodiment 2：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：70 parts of Chinese azalea, The Iron Buddha 56 Part, 45 parts of datura flower, 16 parts of radix aconiti agrestis, 36 parts of the Radix Astragali, 32 parts of Radix Angelicae Sinensis, 22 parts of dried pinellia, 30 parts of arisacma consanguineum schott, 37 parts of rhizoma typhonii, flower 14 parts of 37 parts of green pepper, 28 parts of arabian jasmine root, 27 parts of pseudo-ginseng, 18 parts of calamus, 12 parts of borneol, 22 parts of radix glycyrrhizae and peppermint.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in the ethanol that concentration is 75%, after soak at room temperature 2h, It is warming up to 40 DEG C, ultrasonic extraction 40min, frequency during ultrasonic extraction is 500W, then naturally cools to room temperature, is filtered, filtrate is dense Contracting obtains thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 20 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Wherein, the weight of ethanol is 30 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in step (1).
Wherein, controlled when being coated in step (3) per 1cm2Face paper on be coated with 0.5g arcotic lotion.
Embodiment 3：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：60 parts of Chinese azalea, The Iron Buddha 50 Part, 30 parts of datura flower, 10 parts of radix aconiti agrestis, 25 parts of the Radix Astragali, 25 parts of Radix Angelicae Sinensis, 15 parts of dried pinellia, 20 parts of arisacma consanguineum schott, 30 parts of rhizoma typhonii, flower 8 parts of 28 parts of green pepper, 15 parts of arabian jasmine root, 22 parts of pseudo-ginseng, 10 parts of calamus, 5 parts of borneol, 10 parts of radix glycyrrhizae and peppermint.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in the ethanol that concentration is 75%, after soak at room temperature 2h, It is warming up to 50 DEG C, ultrasonic extraction 60min, frequency during ultrasonic extraction is 700W, then naturally cools to room temperature, is filtered, filtrate is dense Contracting obtains thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 50 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Wherein, the weight of ethanol is 50 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in step (1).
Wherein, controlled when being coated in step (3) per 1cm2Face paper on be coated with 1.2g arcotic lotion.
Embodiment 4：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：75 parts of Chinese azalea, The Iron Buddha 60 Part, 48 parts of datura flower, 18 parts of radix aconiti agrestis, 40 parts of the Radix Astragali, 36 parts of Radix Angelicae Sinensis, 24 parts of dried pinellia, 35 parts of arisacma consanguineum schott, 40 parts of rhizoma typhonii, flower 18 parts of 40 parts of green pepper, 30 parts of arabian jasmine root, 30 parts of pseudo-ginseng, 20 parts of calamus, 15 parts of borneol, 25 parts of radix glycyrrhizae and peppermint.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in the ethanol that concentration is 75%, after soak at room temperature 2h, It is warming up to 0 DEG C, ultrasonic extraction 55min, frequency during ultrasonic extraction is 600W, then naturally cools to room temperature, is filtered, filtrate concentration Obtain thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 40 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Wherein, the weight of ethanol is 45 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in step (1).
Wherein, controlled when being coated in step (3) per 1cm2Face paper on be coated with 0.8g arcotic lotion.
Embodiment 5：
A kind of Chinese medicinal film for surface anesthesia, include the constituent of following parts by weight：65 parts of Chinese azalea, The Iron Buddha 55 Part, 45 parts of datura flower, 18 parts of radix aconiti agrestis, 30 parts of the Radix Astragali, 30 parts of Radix Angelicae Sinensis, 22 parts of dried pinellia, 30 parts of arisacma consanguineum schott, 38 parts of rhizoma typhonii, flower 10 parts of 30 parts of green pepper, 20 parts of arabian jasmine root, 25 parts of pseudo-ginseng, 15 parts of calamus, 10 parts of borneol, 15 parts of radix glycyrrhizae and peppermint.
Wherein, the preparation method of the above-mentioned Chinese medicinal film for surface anesthesia, comprises the following steps：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in the ethanol that concentration is 75%, after soak at room temperature 2h, It is warming up to 40 DEG C, ultrasonic extraction 40min, frequency during ultrasonic extraction is 700W, then naturally cools to room temperature, is filtered, filtrate is dense Contracting obtains thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and Peppermint mixing, crush, sieving, obtain the medicinal powder that particle diameter is 50 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can Arcotic lotion is obtained, arcotic lotion will be obtained and be uniformly coated on face paper, you can for surface anesthesia described in obtaining Chinese medicinal film.
Wherein, the weight of ethanol is 50 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight in step (1).
Wherein, controlled when being coated in step (3) per 1cm2Face paper on be coated with 1.2g arcotic lotion.
Clinical comparison is tested：
The patient for carrying out clinical treatment will be needed to be divided into two groups, the wherein people of control group 85, the people of experimental group 86, wherein, control Group and the M-F of experimental group patient, age differences and coincident with severity degree of condition are essentially identical, no significant difference, have comparable Property.During experiment, experimental group is anaesthetized with Chinese medicinal film of the present invention, and control group carries out local infiltration anesthesia with lidocaine.
Table 1 is Experimental comparison results：
Table 1
To sum up, the present invention have it is rapid-action, anaesthetic effect is good, it is easy to use the advantages of.
It should be noted that herein, such as first and second or the like relational terms are used merely to a reality Body or operation make a distinction with another entity or operation, and not necessarily require or imply and deposited between these entities or operation In any this actual relation or order.Moreover, term " comprising ", "comprising" or its any other variant are intended to Nonexcludability includes, so that process, method, article or equipment including a series of elements not only will including those Element, but also the other element including being not expressly set out, or it is this process, method, article or equipment also to include Intrinsic key element.In the absence of more restrictions, the key element limited by sentence "including a ...", it is not excluded that Other identical element also be present in process, method, article or equipment including the key element.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although with reference to the foregoing embodiments The present invention is described in detail, it will be understood by those within the art that：It still can be to foregoing each implementation Technical scheme described in example is modified, or carries out equivalent substitution to which part technical characteristic；And these modification or Replace, the essence of appropriate technical solution is departed from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (7)

1. a kind of Chinese medicinal film for surface anesthesia, it is characterised in that include the constituent of following parts by weight：Chinese azalea 60- 75 parts, The Iron Buddha 50-60 parts, datura flower 30-48 parts, radix aconiti agrestis 10-18 parts, Radix Astragali 25-40 parts, Radix Angelicae Sinensis 25-36 parts, dried pinellia 15-24 parts, arisacma consanguineum schott 20-35 parts, rhizoma typhonii 30-40 parts, Chinese prickly ash 28-40 parts, arabian jasmine root 15-30 parts, pseudo-ginseng 22-30 parts, Chang Pu 10-20 parts, borneol 5-15 parts, radix glycyrrhizae 10-25 parts and peppermint 8-18 parts.
2. as claimed in claim 1 be used for surface anesthesia Chinese medicinal film, it is characterised in that the composition including following parts by weight into Point：Chinese azalea 65-70 parts, The Iron Buddha 52-56 parts, datura flower 40-45 parts, radix aconiti agrestis 12-16 parts, Radix Astragali 30-36 parts, Radix Angelicae Sinensis 28- 32 parts, dried pinellia 17-22 parts, arisacma consanguineum schott 23-30 parts, rhizoma typhonii 34-37 parts, Chinese prickly ash 30-37 parts, arabian jasmine root 20-28 parts, pseudo-ginseng 25-27 parts, calamus 13-18 parts, borneol 7-12 parts, radix glycyrrhizae 16-22 parts and peppermint 10-14 parts.
3. it is used for the preparation method of the Chinese medicinal film of surface anesthesia as claimed in claim 1 or 2, it is characterised in that including following Step：
(1) Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis are added in ethanol, after soak at room temperature 2h, are warming up to 40-50 DEG C, surpassed Sound extracts 40-60min, then naturally cools to room temperature, filters, and filtrate is concentrated to give thick solid；
(2) by the Radix Astragali, Radix Angelicae Sinensis, dried pinellia, arisacma consanguineum schott, rhizoma typhonii, Chinese prickly ash, arabian jasmine root, pseudo-ginseng, calamus, borneol, radix glycyrrhizae and peppermint Mixing, crush, sieving, obtain the medicinal powder that particle diameter is 20-50 μm；
(3) above-mentioned thick solid, medicinal powder, glycerine and honey are added in distilled water, after being stirred at room temperature uniformly, you can obtain Arcotic lotion, arcotic lotion will be obtained and be uniformly coated on face paper, you can obtain the Chinese medicine for being used for surface anesthesia Film.
4. it is used for the preparation method of the Chinese medicinal film of surface anesthesia as claimed in claim 3, it is characterised in that the step (1) The weight of middle ethanol is 30-50 times of the Chinese azalea, The Iron Buddha, datura flower and radix aconiti agrestis gross weight.
5. it is used for the preparation method of the Chinese medicinal film of surface anesthesia as claimed in claim 3, it is characterised in that the step (1) The concentration of middle ethanol is 75%.
6. it is used for the preparation method of the Chinese medicinal film of surface anesthesia as claimed in claim 3, it is characterised in that the step (1) Frequency during middle ultrasonic extraction is 500-700W.
7. it is used for the preparation method of the Chinese medicinal film of surface anesthesia as claimed in claim 3, it is characterised in that the step (3) Controlled during middle coating per 1cm2Face paper on be coated with 0.5-1.2g arcotic lotion.
CN201710570056.4A 2017-07-13 2017-07-13 A kind of Chinese medicinal film for surface anesthesia and preparation method thereof Pending CN107375586A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272772A (en) * 2018-03-02 2018-07-13 江苏朗沁科技有限公司 A kind of surface surgical anesthesia facial mask

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108272772A (en) * 2018-03-02 2018-07-13 江苏朗沁科技有限公司 A kind of surface surgical anesthesia facial mask

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Application publication date: 20171124