CN107375014A - A kind of external nursing composition - Google Patents

A kind of external nursing composition Download PDF

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Publication number
CN107375014A
CN107375014A CN201710837039.2A CN201710837039A CN107375014A CN 107375014 A CN107375014 A CN 107375014A CN 201710837039 A CN201710837039 A CN 201710837039A CN 107375014 A CN107375014 A CN 107375014A
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CN
China
Prior art keywords
weight
parts
raw material
contain
triethanolamine
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Pending
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CN201710837039.2A
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Chinese (zh)
Inventor
李易春
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUANGDONG YIMING PHARMACEUTICAL CO Ltd
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GUANGDONG YIMING PHARMACEUTICAL CO Ltd
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Priority to CN201710837039.2A priority Critical patent/CN107375014A/en
Publication of CN107375014A publication Critical patent/CN107375014A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The present invention provides a kind of external nursing composition, is made up of the raw material of following parts by weight:The parts by weight of butanediol 57, the parts by weight of sodium carboxymethylcellulose 24, the parts by weight of xanthans 10 12, the parts by weight of carbomer 34, the parts by weight of hyaluronic acid 14 16, the parts by weight of vitamin E 8 10, the parts by weight of triethanolamine 10 11, repeatedly fragrant sour 68 parts by weight, the parts by weight of glyceryl stearate citric acid fat 67, the parts by weight of deionized water 21 36;Compared with prior art, the present invention has following beneficial effect:By scientific composition, trophic factors enriches, and has efficient water lock moistening effect, be adapted to any skin quality crowd to use, can effective skin care, and moisture needed for skin can be supplemented, make skin pleasant, moist, effectively suppress bacteria breed, be outdoor activities crowd's indispensability non-defective unit.

Description

A kind of external nursing composition
Technical field
The present invention is a kind of external nursing composition, belongs to medical cosmetic field.
Background technology
Some external nursing articles for use in the market, particularly external skin nursing materials, mostly targetedly, typically It is divided into female skin nursing materials, male's skin care implement, is adapted to Dry or neutral skin or Oily to use, and Because the collocation of number of types of skin care item materials composition is undesirable, it is impossible to really play a part of skin care, especially in the dry winter Ji Putong skin care item can not play moist effect to skin for a long time, and most of skincare product has to different skin quality Allergic reaction, excitant is larger, and outdoor air pollution is serious in addition, and people do not have a product so far in progress outdoor activities Both can effective skin care, and moisture needed for skin can be supplemented, make skin pleasant, moist, can also effectively suppress bacterium taste Raw, this can not meet public demand.
The content of the invention
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of external nursing composition, it is above-mentioned to solve The problem of being proposed in background technology.
To achieve these goals, the present invention is to realize by the following technical solutions:A kind of external nursing composition, It is made up of the raw material of following parts by weight:Butanediol 5-7 parts by weight, sodium carboxymethylcellulose 2-4 parts by weight, xanthans 10-12 weights Measure part, carbomer 3-4 parts by weight, hyaluronic acid 14-16 parts by weight, vitamin E 8-10 parts by weight, triethanolamine 10-11 weight Part, change fragrant sour 6-8 parts by weight, glyceryl stearate citric acid fat 6-7 parts by weight, deionized water 21-36 parts by weight.
Further, the carboxymethyl cellulose that will be made after native cellulose and the reaction of caustic alkali and monochloroacetic acid in raw material Sodium.
Further, 0.1% aqueous sulfuric acid is heated to 60 DEG C, in 1,2- epoxy butanes are added dropwise in 1h, at 60-70 DEG C Insulation reaction 0.5h, pH7-7.5 is neutralized to 40% liquid caustic soda, after decompression boils off water, then through rectifying, collects 110 DEG C, 3.72kPa points Evaporate and obtain the butanediol in raw material.
Further, cockscomb fragment is added in acetone, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish It is dried, crushes powdering through pulverizer after drying, cockscomb powder is poured into enamel pot, adds 6~7 times of distilled water, stirring Uniformly, more than 24h is soaked, cockscomb powder is fully swelled, then filters, collects filtrate, filter residue soaks 3 times in the same way again, Merge 3 filtered fluids, then filtrate is poured into ceramic cylinder, stir the solid sodium chloride of lower addition 10%, and add isometric chlorine It is imitative, after stirring 3h, aqueous phase is separated, 95% ethanol of 2 times of volumes is added into the aqueous phase separated, is stirred, stands more than 12h, Hyaluronic acid is settled out, is then filtered dry sediment, obtains crude product after drying, crude product is re-dissolved in the 0.1mol/L sodium chloride of 4 times of volumes In solution, pH=4.5~5 are adjusted with watery hydrochloric acid, add isometric chloroform, after stratification, suction out upper strata aqueous phase, aqueous phase PH=7.5 are adjusted with 8% sodium hydroxide solution, add pronase, 24h are incubated at 37 DEG C, then extracted with isometric chloroform Handle 2 times, merging upper strata aqueous phase, lower floor's liquids recovery chloroform, it is molten to add 1% isometric cetylpyridinium chloride in aqueous phase Liquid, stir, staticly settle, filter, collect precipitation, precipitation is dissolved with the 0.4mol/L sodium chloride of 2~3 times of volumes again, mistake Filter, add 3 times of ethanol of volume 95% in filtrate, staticly settle, suck upper strata ethanol, lower floor is again with 95% ethanol repeated precipitation 2 Secondary, lower sediment thing hangs filter, dries, then is washed 2 times with acetone, is dried in vacuo, obtains the hyaluronic acid in raw material.
Further, oxirane, ammoniacal liquor are sent into reactor, in 30-40 DEG C of reaction temperature, reaction pressure 70.9- Under 304kPa, condensation reaction generation one, two, triethanolamine mixed liquor are carried out, at 90-120 DEG C after dehydration concentrates, is sent into three Individual vacuum rectification tower is evaporated under reduced pressure, by different boiling intercept cut, obtain purity up to 99% monoethanolamine, diethanol amine and Triethanolamine finished product, during the course of the reaction, oxirane ratio is increased, while monoethanolamine is removed with steam distillation, add hydrogen Sodium oxide molybdena makes triethanolamine be separated out into alkali metal salt, is neutralized after separation, then carry out the triethanolamine being evaporated under reduced pressure in raw material.
Further, the parts by weight of butanediol 7 are contained in the raw material of every 100 parts by weight, are contained in the raw material of every 100 parts by weight The parts by weight of sodium carboxymethylcellulose 2, contain the parts by weight of xanthans 12, the raw material of every 100 parts by weight in the raw material of every 100 parts by weight In contain the parts by weight of carbomer 3, contain the parts by weight of hyaluronic acid 14, the raw material of every 100 parts by weight in the raw material of every 100 parts by weight In contain the parts by weight of vitamin E 10, contain the parts by weight of triethanolamine 10 in the raw material of every 100 parts by weight, every 100 parts by weight Contain repeatedly fragrant sour 8 parts by weight in raw material, contain the parts by weight of glyceryl stearate citric acid fat 6 in the raw material of every 100 parts by weight, often Contain the parts by weight of deionized water 28 in the raw material of 100 parts by weight.
Beneficial effects of the present invention:A kind of external nursing composition of the present invention, it is rich by scientific composition, trophic factors Richness, there is efficient water lock moistening effect, be adapted to any skin quality crowd to use, can effective skin care, and can supplement needed for skin Moisture, make skin pleasant, moist, effectively suppress bacteria breed, be outdoor activities crowd's indispensability non-defective unit.
Embodiment
To be easy to understand the technical means, the inventive features, the objects and the advantages of the present invention, with reference to Embodiment, the present invention is expanded on further.
The present invention provides a kind of technical scheme:A kind of external nursing composition, is made up of the raw material of following parts by weight:Fourth two Alcohol 5-7 parts by weight, sodium carboxymethylcellulose 2-4 parts by weight, xanthans 10-12 parts by weight, carbomer 3-4 parts by weight, hyalomitome Sour 14-16 parts by weight, vitamin E 8-10 parts by weight, triethanolamine 10-11 parts by weight, repeatedly fragrant sour 6-8 parts by weight, glycerine are hard Fat citric acid fat 6-7 parts by weight, deionized water 21-36 parts by weight.
The sodium carboxymethylcellulose that will be made after native cellulose and the reaction of caustic alkali and monochloroacetic acid in raw material.
0.1% aqueous sulfuric acid is heated to 60 DEG C, in 1,2- epoxy butanes are added dropwise in 1h, in 60-70 DEG C of insulation reaction 0.5h, pH7-7.5 is neutralized to 40% liquid caustic soda, is depressurized after boiling off water, then be fractionated and obtain former through rectifying, 110 DEG C of collection, 3.72kPa Butanediol in material.
Cockscomb fragment is added in acetone, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish and is dried, Powdering is crushed through pulverizer after drying, cockscomb powder is poured into enamel pot, 6~7 times of distilled water is added, stirs, is soaked More than 24h, cockscomb powder is fully swelled, then filter, collect filtrate, filter residue soaks 3 times in the same way again, merges 3 mistakes Filtrate, then filtrate is poured into ceramic cylinder, the solid sodium chloride of lower addition 10% is stirred, and isometric chloroform is added, stir 3h Afterwards, aqueous phase is separated, 95% ethanol of 2 times of volumes is added into the aqueous phase separated, is stirred, more than 12h is stood, is settled out Bright matter acid, is then filtered dry sediment, and crude product is obtained after drying, and crude product is re-dissolved in the 0.1mol/L sodium chloride solutions of 4 times of volumes, is used Watery hydrochloric acid adjusts pH=4.5~5, adds isometric chloroform, after stratification, suctions out upper strata aqueous phase, 8% hydroxide of aqueous phase Sodium solution adjusts pH=7.5, adds pronase, is incubated 24h at 37 DEG C, then with isometric chloroform extraction processing 2 times, closes And upper strata aqueous phase, lower floor's liquids recovery chloroform, 1% isometric cetylpyridinium chloride solution is added in aqueous phase, stirring is equal It is even, staticly settle, filter, collect precipitation, precipitation is dissolved with the 0.4mol/L sodium chloride of 2~3 times of volumes again, filtering, in filtrate 3 times of ethanol of volume 95% are added, are staticly settled, suck upper strata ethanol, again with 95% ethanol repeated precipitation 2 times, lower floor sinks for lower floor Starch hangs filter, dries, then is washed 2 times with acetone, is dried in vacuo, obtains the hyaluronic acid in raw material.
Oxirane, ammoniacal liquor are sent into reactor, under 30-40 DEG C of reaction temperature, reaction pressure 70.9-304kPa, Condensation reaction generation one, two, triethanolamine mixed liquor are carried out, at 90-120 DEG C after dehydration concentrates, is sent into three decompression essences Evaporate tower to be evaporated under reduced pressure, intercept cut by different boiling, obtain purity up to 99% monoethanolamine, diethanol amine and triethanolamine Finished product, during the course of the reaction, oxirane ratio is increased, while monoethanolamine is removed with steam distillation, adding sodium hydroxide makes Triethanolamine separates out into alkali metal salt, is neutralized after separation, then carry out the triethanolamine being evaporated under reduced pressure in raw material.
As one embodiment of the present of invention:Contain the parts by weight of butanediol 7, every 100 weight in the raw material of every 100 parts by weight Contain the parts by weight of sodium carboxymethylcellulose 2 in the raw material of part, contain the parts by weight of xanthans 12 in the raw material of every 100 parts by weight, often Contain the parts by weight of carbomer 3 in the raw material of 100 parts by weight, contain the parts by weight of hyaluronic acid 14 in the raw material of every 100 parts by weight, often Contain the parts by weight of vitamin E 10 in the raw material of 100 parts by weight, contain the weight of triethanolamine 10 in the raw material of every 100 parts by weight Part, fragrant sour 8 parts by weight are contained repeatedly in the raw material of every 100 parts by weight, contain glyceryl stearate lemon in the raw material of every 100 parts by weight The sour parts by weight of fat 6, contain the parts by weight of deionized water 28 in the raw material of every 100 parts by weight.
As one embodiment of the present of invention:A kind of external nursing composition of the present invention, by scientific composition, nutrition because Son is abundant, has efficient water lock moistening effect, is adapted to any skin quality crowd use, can effective skin care, and skin can be supplemented Required moisture, make skin pleasant, moist, effectively suppress bacteria breed, be outdoor activities crowd's indispensability non-defective unit.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above, for this area skill For art personnel, it is clear that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing substantially from the present invention spirit or In the case of essential characteristic, the present invention can be realized in other specific forms.Which point therefore, no matter from the point of view of, all should incite somebody to action Embodiment regards exemplary as, and be it is nonrestrictive, the scope of the present invention by appended claims rather than on state Bright restriction, it is intended that all changes fallen in the implication and scope of the equivalency of claim are included in the present invention It is interior.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (6)

  1. A kind of 1. external nursing composition, it is characterised in that:It is made up of the raw material of following parts by weight:Butanediol 5-7 parts by weight, Sodium carboxymethylcellulose 2-4 parts by weight, xanthans 10-12 parts by weight, carbomer 3-4 parts by weight, hyaluronic acid 14-16 weight Part, vitamin E 8-10 parts by weight, triethanolamine 10-11 parts by weight, change fragrant sour 6-8 parts by weight, glyceryl stearate citric acid fat 6-7 parts by weight, deionized water 21-36 parts by weight.
  2. A kind of 2. external nursing composition according to claim 1, it is characterised in that:By native cellulose and caustic alkali and The sodium carboxymethylcellulose in raw material is made after monochloroacetic acid reaction.
  3. A kind of 3. external nursing composition according to claim 1, it is characterised in that:0.1% aqueous sulfuric acid is heated to 60 DEG C, in 1,2- epoxy butanes are added dropwise in 1h, in 60-70 DEG C of insulation reaction 0.5h, pH7-7.5 is neutralized to 40% liquid caustic soda, is depressurized After boiling off water, then through rectifying, collect 110 DEG C, 3.72kPa fractionation and butanediol in raw material.
  4. A kind of 4. external nursing composition according to claim 1, it is characterised in that:Cockscomb fragment is added to acetone In, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish and is dried, powdering is crushed through pulverizer after drying, will Cockscomb powder is poured into enamel pot, is added 6~7 times of distilled water, is stirred, and is soaked more than 24h, cockscomb powder is fully swelled, so After filter, collect filtrate, filter residue soaks 3 times, merges 3 filtered fluids, then filtrate is poured into ceramic cylinder, stirred in the same way again The solid sodium chloride of lower addition 10% is mixed, and adds isometric chloroform, after stirring 3h, aqueous phase is separated, adds into the aqueous phase separated Enter 95% ethanol of 2 times of volumes, stir, stand more than 12h, be settled out hyaluronic acid, be then filtered dry sediment, after drying Crude product is obtained, crude product is re-dissolved in the 0.1mol/L sodium chloride solutions of 4 times of volumes, is adjusted pH=4.5~5 with watery hydrochloric acid, is added The chloroform of volume, after stratification, suction out upper strata aqueous phase, aqueous phase 8% sodium hydroxide solution regulation pH=7.5, addition chain enzyme egg White enzyme, is incubated 24h at 37 DEG C, then with isometric chloroform extraction processing 2 times, merges upper strata aqueous phase, lower floor's liquids recovery chloroform, 1% isometric cetylpyridinium chloride solution is added in aqueous phase, stirs, staticly settles, is filtered, collects precipitation, precipitation Dissolved again with the 0.4mol/L sodium chloride of 2~3 times of volumes, filtering, add 3 times of ethanol of volume 95% in filtrate, staticly settle, Sucking upper strata ethanol, again with 95% ethanol repeated precipitation 2 times, lower sediment thing hangs filter, dries, then is washed 2 times with acetone for lower floor, Vacuum drying, obtains the hyaluronic acid in raw material.
  5. A kind of 5. external nursing composition according to claim 1, it is characterised in that:Oxirane, ammoniacal liquor are sent into anti- Answer in device, under 30-40 DEG C of reaction temperature, reaction pressure 70.9-304kPa, carry out condensation reaction generation one, two, triethanolamine Mixed liquor, at 90-120 DEG C after dehydration concentrates, it is sent into three vacuum rectification towers and is evaporated under reduced pressure, intercepted by different boiling Cut, purity is obtained up to 99% monoethanolamine, diethanol amine and triethanolamine finished product, during the course of the reaction, increases oxirane ratio Example, at the same with steam distillation remove monoethanolamine, add sodium hydroxide triethanolamine is separated out into alkali metal salt, after separation in With, then carry out the triethanolamine being evaporated under reduced pressure in raw material.
  6. A kind of 6. external nursing composition according to claim 1, it is characterised in that:Contain in the raw material of every 100 parts by weight There are the parts by weight of butanediol 7, contain the parts by weight of sodium carboxymethylcellulose 2, the original of every 100 parts by weight in the raw material of every 100 parts by weight Contain the parts by weight of xanthans 12 in material, contain the parts by weight of carbomer 3, the raw material of every 100 parts by weight in the raw material of every 100 parts by weight In contain the parts by weight of hyaluronic acid 14, contain the parts by weight of vitamin E 10 in the raw material of every 100 parts by weight, every 100 parts by weight Contain the parts by weight of triethanolamine 10 in raw material, contain repeatedly fragrant sour 8 parts by weight, every 100 parts by weight in the raw material of every 100 parts by weight Raw material in contain the parts by weight of glyceryl stearate citric acid fat 6, contain the parts by weight of deionized water 28 in the raw material of every 100 parts by weight.
CN201710837039.2A 2017-09-17 2017-09-17 A kind of external nursing composition Pending CN107375014A (en)

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Application Number Priority Date Filing Date Title
CN201710837039.2A CN107375014A (en) 2017-09-17 2017-09-17 A kind of external nursing composition

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CN201710837039.2A CN107375014A (en) 2017-09-17 2017-09-17 A kind of external nursing composition

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109096885A (en) * 2018-07-20 2018-12-28 马玉玲 A kind of component surface corrosion prevention rust preventer
CN111359305A (en) * 2020-04-21 2020-07-03 江苏更美科技有限公司 Preparation method and device of hyaluronic acid with moisturizing effect for skin care

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008032212A3 (en) * 2006-09-08 2009-04-23 Foamix Ltd Colored or colorable foamable composition and foam
CN103230353A (en) * 2013-05-03 2013-08-07 湖南御泥坊化妆品有限公司 Additive-free natural whitening cosmetic and preparation method thereof
CN107032994A (en) * 2017-04-14 2017-08-11 广东丸美生物技术股份有限公司 A kind of extraction process of Rosmarinic acid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008032212A3 (en) * 2006-09-08 2009-04-23 Foamix Ltd Colored or colorable foamable composition and foam
CN103230353A (en) * 2013-05-03 2013-08-07 湖南御泥坊化妆品有限公司 Additive-free natural whitening cosmetic and preparation method thereof
CN107032994A (en) * 2017-04-14 2017-08-11 广东丸美生物技术股份有限公司 A kind of extraction process of Rosmarinic acid

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109096885A (en) * 2018-07-20 2018-12-28 马玉玲 A kind of component surface corrosion prevention rust preventer
CN111359305A (en) * 2020-04-21 2020-07-03 江苏更美科技有限公司 Preparation method and device of hyaluronic acid with moisturizing effect for skin care
CN111359305B (en) * 2020-04-21 2021-01-01 江苏更美科技有限公司 Preparation method and device of hyaluronic acid with moisturizing effect for skin care

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