CN107335016A - 一种治疗胁满、胸痹病证的丸剂药物及其制备方法 - Google Patents

一种治疗胁满、胸痹病证的丸剂药物及其制备方法 Download PDF

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CN107335016A
CN107335016A CN201710614186.3A CN201710614186A CN107335016A CN 107335016 A CN107335016 A CN 107335016A CN 201710614186 A CN201710614186 A CN 201710614186A CN 107335016 A CN107335016 A CN 107335016A
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root
rhizoma
medicine
obstruction
radix
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Sichuan Jintang Haina Biomedical Technology Institute
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Abstract

本发明属于中药制剂领域,目的是根据中医治疗胁满、胸痹病证的认识机理而提供的一种治疗胁满、胸痹病证的丸剂药物,所述药物的各个组分及其质量份比如下:枳实95g、木香115g、桃仁115g、香附95g、陈皮80g、枳壳80g、熟地黄280g、柴胡95g、赤芍95g、白芍115g、五灵脂120g、牡丹皮130g、黄芩95g、黄连31g、桂枝80g、大黄115g、龙胆草60g、芦荟46g、郁李仁80g、苍术80g、厚朴95g、神曲200g、炒麦芽115g、鸡内金95g、川芎95g、郁金95g、丹参120g、红花95g、三棱95g、莪术95g、穿山甲80g、半夏80g、前胡80g、白前80g、石菖蒲80g、葛根115g、麝香1g、苏合香8g、安息香12g等;本发明提供的药物是一个很好的中药组方。

Description

一种治疗胁满、胸痹病证的丸剂药物及其制备方法
技术领域
本发明属于中药制剂领域,具体涉及一种治疗胁满、胸痹病证的丸剂药物,特别是供胁满、胸痹病证患者使用的丸剂药物及其制备方法的领域。
背景技术
祖国医学认为:胸痹,胸痹是指以胸部闷痛、甚则胸痛彻背,喘息不得卧为主要表现的一种疾病,轻者感觉胸闷,呼吸欠畅,重者则有胸痛,严重者心痛彻背,背痛彻心。汉代张仲景《金匮要略》中提出“胸痹”的名称,归纳病机为“阳微阴弦”,治疗上温通散寒方药有瓜蒌薤白白酒汤及瓜蒌薤白半夏汤等。根据本证的临床特点,主要与现代医学所指的冠状动脉粥样硬化性心脏病(心绞痛、心肌梗死)关系密切。
其临床表现为:胸部闷痛、甚则胸痛彻背,喘息不得卧为主证,或胸闷,呼吸欠畅,重者则有胸痛,严重者心痛彻背,背痛彻心。脉弦或结代。
那么,就如何找到一种可有效治疗胁满、胸痹病证的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗胁满、胸痹病证上,人们逐渐意识到了中医治疗胁满、胸痹病证的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗胁满、胸痹病证的现状,本发明的目的是在于提供一种治疗胁满、胸痹病证的丸剂药物,以解决胁满、胸痹病证患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述胁满、胸痹病证。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗胁满、胸痹病证的丸剂药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实30~120g、木香80~160g、桃仁80~160g、香附50~120g、陈皮30~100g、枳壳30~100g、熟地黄150~380g、柴胡30~120g、赤芍40~120g、白芍50~150g、五灵脂50~160g、牡丹皮80~180g、黄芩30~120g、黄连20~40g、桂枝30~100g、大黄30~150g、龙胆草30~80g、芦荟20~60g、郁李仁60~100g、苍术30~100g、厚朴30~120g、神曲100~250g、炒麦芽90~160g、鸡内金30~120g、川芎50~120g、郁金30~120g、丹参50~160g、红花30~120g、三棱50~120g、莪术30~120g、穿山甲50~100g、半夏30~100g、前胡30~100g、白前30~100g、石菖蒲30~100g、葛根100~160g、麝香0.50~1.5g、苏合香3~10g、安息香6~16g、零陵香80~160g、蒲黄50~100g、蟾酥0.15~3.5g、当归60~120g、甘松30~70g,淀粉适量。
一种治疗胁满、胸痹病证的丸剂药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实38~105g、木香90~130g、桃仁90~130g、香附58~105g、陈皮38~90g、枳壳38~90g、熟地黄180~330g、柴胡38~105g、赤芍46~105g、白芍58~130g、五灵脂58~140g、牡丹皮90~150g、黄芩38~105g、黄连23~35g、桂枝38~90g、大黄38~130g、龙胆草38~70g、芦荟26~52g、郁李仁70~90g、苍术38~90g、厚朴38~105g、神曲115~220g、炒麦芽100~130g、鸡内金38~105g、川芎58~105g、郁金38~105g、丹参58~140g、红花38~105g、三棱58~105g、莪术38~105g、穿山甲58~90g、半夏38~90g、前胡38~90g、白前38~90g、石菖蒲38~90g、葛根115~130g、麝香0.80~1.2g、苏合香5~9g、安息香7~13g、零陵香90~130g、蒲黄58~90g、蟾酥0.18~3.2g、当归68~105g、甘松38~60g,淀粉适量。
一种治疗胁满、胸痹病证的丸剂药物及其制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其质量份比如下所示:
枳实95g、木香115g、桃仁115g、香附95g、陈皮80g、枳壳80g、熟地黄280g、柴胡95g、赤芍95g、白芍115g、五灵脂120g、牡丹皮130g、黄芩95g、黄连31g、桂枝80g、大黄115g、龙胆草60g、芦荟46g、郁李仁80g、苍术80g、厚朴95g、神曲200g、炒麦芽115g、鸡内金95g、川芎95g、郁金95g、丹参120g、红花95g、三棱95g、莪术95g、穿山甲80g、半夏80g、前胡80g、白前80g、石菖蒲80g、葛根115g、麝香1g、苏合香8g、安息香12g、零陵香115g、蒲黄80g、蟾酥3g、当归95g、甘松50g,淀粉适量。
一种治疗胁满、胸痹病证的丸剂药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除淀粉外,将上述原料中药拣去杂质、粉尘及减压干燥后,按照质量份比共研磨成极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物和淀粉过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:3.8mm~4.0mm),继而烘干、消毒,分装密封即可。
一种治疗胁满、胸痹病证的丸剂药物及其制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量6.5g/次,饭后服,一个月为一疗程。服药2~5个疗程,症状逐渐减轻或痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
枳实,性味:苦、辛、酸、温,具有破气消积、化痰散痞之功效,用于治疗积滞内停、痞满胀痛、泻痢后重、大便不通、痰滞气阻胸痹、结胸、胃下垂、脱肛、子宫脱垂;
木香,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、症瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒;
桃仁,性味:苦甘、平,无毒,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘;
香附,性味:味辛、微寒,无毒,具有理气解郁、调经止痛、安胎之功效,用于治疗胁肋胀痛、乳房胀育、疝气疼痛、月经不调、脘腹痞满疼痛、嗳气吞酸、呕恶、经行腹痛、崩漏带下、胎动不安;
陈皮,性味:苦、辛、温,具有理气健脾、燥湿化痰之功效,用于治疗胸脘胀满、食少吐泻、咳嗽痰多;
枳壳,性味:苦、酸、性微寒,具有理气宽胸、行滞消积之功效,用于治疗胸隔痞满、胁肋胀痛、食积不化、脘腹胀满、下痢后重、脱肛、子宫脱垂;
熟地黄,性味:甘、微温,具有滋阴补血、益精填髓之功效,用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白;
柴胡,性味:味苦、辛、性微寒,具有解表退热、疏肝解郁、升举阳气之功效,用于治疗外感发热、寒热往来、疟疾、肝郁胁痛乳胀、头痛头眩、月经不调、气虚下陷之脱肛、子宫脱垂、胃下垂等症;
赤芍,性味:苦、微寒,具有清热凉血;活血祛瘀之功效,用于治疗温毒发斑;吐血衄血;肠风下血;目赤肿痛;痈肿疮疡;闭经;痛经;崩带淋浊;瘀滞胁痛;疝瘕积聚;跌扑损伤;
白芍,性味:苦、酸、微寒,具有养血和营、缓急止痛、敛阴平肝之功效,用于治疗月经不调、经行腹痛、崩漏、自汗、盗汗、胁肋脘腹疼痛、四肢挛痛、头痛、眩晕等症;
五灵脂,性味:甘、温,具有活血散瘀、炒炭止血之功效,用于治疗心腹淤血作痛、痛经、血瘀经闭、产后淤血腹痛,炒炭治崩漏下血、外用治跌打损伤,蛇、虫咬伤;
牡丹皮,性味:辛苦、凉、微寒,具有清热、活血散瘀之功效,用于治疗温热病热入血分、发斑、吐衄、热泪盈眶病菌后期热伏阴分发热、阴虚骨蒸潮热、血滞经闭、痛经、痈肿疮毒、跌扑伤痛、风湿热痹等症;
黄芩,性味:味苦、性寒,具有清热泻火、燥湿解毒、止血、安胎之功效,用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疔疮;
黄连,性味:苦、寒,具有清热泻火、燥湿、解毒之功效,用于治疗热病邪入心经之高热、烦躁、谵妄或热盛迫血妄行之吐衄、湿热胸痞、泄泻、痢疾、心火亢盛之心烦失眠、胃热呕吐或消谷善饥、肝火目赤肿痛、以及热毒疮疡、疔毒走黄、牙龈肿痛、口舌生疮、聤耳、阴肿、痔血、湿疹、烫伤等症;
桂枝,性味:辛、甘、温,具有发汗解肌、温通经脉、助阳化气,平冲降气之功效,用于治疗风寒感冒、脘腹冷痛、血寒经闭、关节痹痛、痰饮、水肿、心悸、奔豚等症;
大黄,性味:苦、性寒,具有攻积滞、清湿热、泻火、凉血、祛瘀、解毒之功效,用于治疗实热便秘、热结胸痞、湿热泻痢、黄疸、淋病、水肿腹满、小便不利、目赤、咽喉肿痛、口舌生疮、胃热呕吐、吐血、咯血、衄血、便血、尿血、蓄血、经闭、产后瘀滞腹痛、癥瘕积聚、跌打损伤、热毒痈疡、丹毒、烫伤风等症;
龙胆草,性味:味苦、性寒,具有清热燥湿、泻肝胆火之功效,用于治疗清热燥湿、泻肝胆火,用于湿热黄疸、阴肿阴痒、带下、湿疹瘙痒、肝火目赤、耳鸣耳聋、胁痛口苦、强中、惊风抽搐;
芦荟,性味:味苦、寒,具有清肝热、通便之功效,用于治疗便秘、小儿疳积、惊风,外治湿癣;
郁李仁,性味:味辛、苦、甘、平,具有润燥滑肠、下气、利水之功效,用于治疗津枯肠燥、食积气滞、腹胀便秘、水肿、脚气、小便不利;
苍术,性味:味辛、苦、性温,具有燥湿健脾、祛风湿、明目之功效,用于治疗湿困脾胃、倦怠嗜卧、胞痞腹胀、食欲不振、呕吐泄泻、痰饮、湿肿、表证夹湿、头身重痛、痹证温性、肢节酸痛重着、痿襞、夜盲等症;
厚朴, 性味:苦、辛、温,具有燥湿消痰、下气除满之功效,用于治疗湿阻中焦,脘腹胀满,食积气滞,腹胀便秘, 痰饮喘咳;此外,七情郁结,痰气互阻,咽中如有物阻,咽之不下,吐之不出的梅核气证,亦可取本品燥湿消痰,下气宽中之效;
神曲,性味:甘辛、温,具有健脾和胃、消食调中之功效,用于治疗饮食停滞、胸痞腹胀、呕吐泻痢、产后瘀血腹痛、小儿腹大坚积等症;
炒麦芽,性味:甘、平,具有行气消食、健脾开胃、退乳消胀之功效,用于治疗食积不消、脘腹胀痛、脾虚食少、乳汁郁积、乳房胀痛、妇女断乳;生麦芽:健脾和胃、疏肝行气,用于脾虚食少、乳汁郁积;炒麦芽:行气消食回乳,用于食积不消、妇女断乳;焦麦芽、消食化滞,用于食积不消、脘腹胀痛;
鸡内金,性味:味甘、平,具有健胃消食、涩精止遗之功效,用于治疗食积不消、呕吐泻痢、小儿疳积、遗尿、遗精等症;
川芎,性味:辛、温,具有行气开郁、法风燥湿、活血止痛之功效,用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、月经不调、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛;
郁金,性味:味辛、苦、性寒,具有活血止能、行气解郁、清心凉血、疏肝利胆之功效,用于治疗胸腹胁肋诸痛、妇女痛经、经闭、癥瘕结块、热病神昏、癫狂、惊痫、吐血、衄备、血淋、砂淋、黄疸等症;
丹参,性味:味苦;性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、癥瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒;
红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛癥瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症;
三棱,性味:味辛、涩、凉,具有破血行气、消积止痛之功效,用于治疗症瘕痞块、瘀滞经闭、痛经、食积胀痛、跌年伤痛;
莪术,性味:味辛;苦;性温,具有行气破血、消积止痛之功效,用于治疗血气心痛、饮食积滞、脘腹胀痛、血滞经闭、痛经、癥瘕瘤痞块、跌打损伤;
穿山甲,性味:咸、微寒,具有通经下乳、消肿排脓、搜风通络之功效,用于治疗经闭癓瘕、乳汁不通、痈肿疮毒、关节痹痛、麻木拘挛;
半夏,性味:辛、温,有毒,具有燥湿化痰、降逆止呕、消痞散结之功效,用于治疗痰多咳喘、痰饮眩悸、风痰眩晕、痰厥头痛、呕吐反胃、胸脘痞闷、梅核气,生用外治痈肿痰核,姜半夏多用于降逆止呕;
前胡,性味:苦、辛、微寒,具有散风清热,降气化痰之功效,用于治疗风热咳嗽痰多、痰热喘满、咯痰黄稠;
白前,性味:辛、苦、微温,具有降气、消痰、止咳之功效,用于治疗肺气壅实、咳嗽痰多、胸满喘急;
石菖蒲,性味:味辛、苦、温,具有化湿开胃、开窍豁痰、醒神益智之功效,用于治疗脘痞不饥、噤口下痢、神昏癫痫、健忘耳聋等症;
葛根,性味:甘、辛、平,具有解肌退热、发表透诊、生津止渴、升阳止泻之功效,用于治疗外感发热、头项强痛、麻疹初起、疹出不畅、温病口渴、消渴病、泄泻、痢疾、高血压、冠心病等症;
麝香,性味:味辛、温,具有开窍醒神、活血通经、消肿止痛之功效,用于治疗热病神昏、中风痰厥、气郁暴厥、中恶昏迷、经闭、癓瘕、难产死胎、心腹暴痛、痈肿瘰疬、咽喉肿痛、跌扑伤痛、痹痛麻木;
苏合香,性味:味辛、温,具有开窃、辟秽、止痛之功效,用于治疗中风痰厥、猝然昏倒、胸腹冷痛、惊痫等症;
安息香,性味:味辛、苦、平,具有开窃清神、行气活血、止痛之功效,用于治疗中风痰厥、气郁暴厥、中恶昏迷、心腹疼痛、产后血晕、小儿惊风;
零陵香,性味:辛甘、温,具有祛风寒、辟秽浊之功效,用于治疗伤寒、感冒头痛、胸腹胀满、下利、遗精、鼻塞、牙痛等症;
蒲黄,性味:甘、平,具有止血、化瘀、通淋之功效,用于治疗吐血,衄血、咯血、崩漏、外伤出血、经闭痛经、脘腹刺痛、跌扑肿痛、血淋涩痛;
蟾酥,性味:辛、温,有毒,具有解毒、止痛、开窍醒神之功效,用于治疗痈疽疔疮、咽喉肿痛、中暑神昏、腹痛吐泻;
当归,性味:味甘、辛、苦、性温,具有补血、活血、调经止痛、润燥滑肠之功效,用于治疗血虚诸证、月经不调、经闭、痛经、癥瘕结聚、崩漏、虚寒腹痛、痿痹、肌肤麻木、肠燥便难、赤痢后重、痈疽疮疡、跌扑损伤等症;
甘松,性味:辛、甘、温,具有理气止痛、开郁醒脾之功效,用于治疗脘腹胀满、食欲不振、呕吐,外治牙痛、脚肿等症。
本发明药物是基于中医治疗胁满、胸痹病证的原则,从依据胁满、胸痹病证的病理机制及药理作用认为:就胁满、胸痹病证,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述胁满、胸痹病证的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实95g、木香115g、桃仁115g、香附95g、陈皮80g、枳壳80g、熟地黄280g、柴胡95g、赤芍95g、白芍115g、五灵脂120g、牡丹皮130g、黄芩95g、黄连31g、桂枝80g、大黄115g、龙胆草60g、芦荟46g、郁李仁80g、苍术80g、厚朴95g、神曲200g、炒麦芽115g、鸡内金95g、川芎95g、郁金95g、丹参120g、红花95g、三棱95g、莪术95g、穿山甲80g、半夏80g、前胡80g、白前80g、石菖蒲80g、葛根115g、麝香1g、苏合香8g、安息香12g、零陵香115g、蒲黄80g、蟾酥3g、当归95g、甘松50g,淀粉适量。
实施例2:
一种治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实105g、木香130g、桃仁130g、香附105g、陈皮90g、枳壳90g、熟地黄330g、柴胡105g、赤芍105g、白芍130g、五灵脂140g、牡丹皮150g、黄芩105g、黄连35g、桂枝90g、大黄130g、龙胆草70g、芦荟52g、郁李仁90g、苍术90g、厚朴105g、神曲220g、炒麦芽130g、鸡内金105g、川芎105g、郁金105g、丹参140g、红花105g、三棱105g、莪术105g、穿山甲90g、半夏90g、前胡90g、白前90g、石菖蒲90g、葛根130g、麝香1.2g、苏合香9g、安息香13g、零陵香130g、蒲黄90g、蟾酥3.2g、当归105g、甘松60g,淀粉适量。
实施例3:
一种治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实120g、木香160g、桃仁160g、香附120g、陈皮100g、枳壳100g、熟地黄380g、柴胡120g、赤芍120g、白芍150g、五灵脂160g、牡丹皮180g、黄芩120g、黄连40g、桂枝100g、大黄150g、龙胆草80g、芦荟60g、郁李仁100g、苍术100g、厚朴120g、神曲250g、炒麦芽160g、鸡内金120g、川芎120g、郁金120g、丹参160g、红花120g、三棱120g、莪术120g、穿山甲100g、半夏100g、前胡100g、白前100g、石菖蒲100g、葛根160g、麝香1.5g、苏合香10g、安息香16g、零陵香160g、蒲黄100g、蟾酥3.5g、当归120g、甘松70g,淀粉适量。
典型病例
经临床诊断治疗胁满、胸痹病证患者共1180例,年龄为57岁以上的820例,只有360例为57岁以下。1180例患者中痊愈的850例,有效的212例, 无效的118例。总有效率达90%。

Claims (3)

1.一种治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实30~120g、木香80~160g、桃仁80~160g、香附50~120g、陈皮30~100g、枳壳30~100g、熟地黄150~380g、柴胡30~120g、赤芍40~120g、白芍50~150g、五灵脂50~160g、牡丹皮80~180g、黄芩30~120g、黄连20~40g、桂枝30~100g、大黄30~150g、龙胆草30~80g、芦荟20~60g、郁李仁60~100g、苍术30~100g、厚朴30~120g、神曲100~250g、炒麦芽90~160g、鸡内金30~120g、川芎50~120g、郁金30~120g、丹参50~160g、红花30~120g、三棱50~120g、莪术30~120g、穿山甲50~100g、半夏30~100g、前胡30~100g、白前30~100g、石菖蒲30~100g、葛根100~160g、麝香0.50~1.5g、苏合香3~10g、安息香6~16g、零陵香80~160g、蒲黄50~100g、蟾酥0.15~3.5g、当归60~120g、甘松30~70g,淀粉适量。
2.根据权利要求1所述的治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实38~105g、木香90~130g、桃仁90~130g、香附58~105g、陈皮38~90g、枳壳38~90g、熟地黄180~330g、柴胡38~105g、赤芍46~105g、白芍58~130g、五灵脂58~140g、牡丹皮90~150g、黄芩38~105g、黄连23~35g、桂枝38~90g、大黄38~130g、龙胆草38~70g、芦荟26~52g、郁李仁70~90g、苍术38~90g、厚朴38~105g、神曲115~220g、炒麦芽100~130g、鸡内金38~105g、川芎58~105g、郁金38~105g、丹参58~140g、红花38~105g、三棱58~105g、莪术38~105g、穿山甲58~90g、半夏38~90g、前胡38~90g、白前38~90g、石菖蒲38~90g、葛根115~130g、麝香0.80~1.2g、苏合香5~9g、安息香7~13g、零陵香90~130g、蒲黄58~90g、蟾酥0.18~3.2g、当归68~105g、甘松38~60g,淀粉适量。
3.根据权利要求1至2所述的治疗胁满、胸痹病证的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
枳实95g、木香115g、桃仁115g、香附95g、陈皮80g、枳壳80g、熟地黄280g、柴胡95g、赤芍95g、白芍115g、五灵脂120g、牡丹皮130g、黄芩95g、黄连31g、桂枝80g、大黄115g、龙胆草60g、芦荟46g、郁李仁80g、苍术80g、厚朴95g、神曲200g、炒麦芽115g、鸡内金95g、川芎95g、郁金95g、丹参120g、红花95g、三棱95g、莪术95g、穿山甲80g、半夏80g、前胡80g、白前80g、石菖蒲80g、葛根115g、麝香1g、苏合香8g、安息香12g、零陵香115g、蒲黄80g、蟾酥3g、当归95g、甘松50g,淀粉适量。
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