CN107334815A - A kind of pharmaceutical composition for treating cranial vascular disease and preparation method thereof - Google Patents

A kind of pharmaceutical composition for treating cranial vascular disease and preparation method thereof Download PDF

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CN107334815A
CN107334815A CN201710604712.8A CN201710604712A CN107334815A CN 107334815 A CN107334815 A CN 107334815A CN 201710604712 A CN201710604712 A CN 201710604712A CN 107334815 A CN107334815 A CN 107334815A
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pharmaceutical composition
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leech
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李金华
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    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The present invention relates to a kind of pharmaceutical composition for treating cranial vascular disease and preparation method thereof, it is related to field of medicaments.The pharmaceutical composition includes the first bulk drug, and the first bulk drug includes:The bush of 14 16 parts by weight;The red sage root of 14 16 parts by weight;The leech of 46 parts by weight;The earthworm of 9 12 parts by weight;And 69 parts by weight process naze, effectively treat or prevent the diseases such as cerebral infarction, cerebral hemorrhage brain, and prevent because above-mentioned illness causes complications or sequelae.The preparation method of aforementioned pharmaceutical compositions is to mix the first raw material medicaments in part by weight number, crushes, decoction at least 20 minutes is mixed with water, obtains filtrate, and this method is simply controllable, easy to operation, and large-scale production can be achieved.

Description

A kind of pharmaceutical composition for treating cranial vascular disease and preparation method thereof
Technical field
The present invention relates to field of medicaments, and more particularly to a kind of pharmaceutical composition for treating cranial vascular disease and its preparation side Method.
Background technology
The cranial vascular diseases such as existing some treatment cerebral infarction, cerebral hemorrhages, and prevent because above-mentioned cranial vascular disease causes disease hair The medicine and method of disease or sequelae, aphasia from apoplexy etc., have deficiency, it is impossible to reach the effect treated both principal and secondary aspect of disease.
The content of the invention
It is an object of the invention to provide a kind of pharmaceutical composition for treating cranial vascular disease, has qi and activate blood circulation, by the stasis of blood Dredging collateral, phlegm reduction of blood circulation promoting, ceases wind reduce blood fat and other effects, effectively treat or prevent the diseases such as cerebral infarction, cerebral hemorrhage, and prevent because above-mentioned Illness causes complications or sequelae.
Another object of the present invention is to the preparation method for the pharmaceutical composition for providing above-mentioned treatment cranial vascular disease, operation Simply, it is controllable, quickly obtain finished product.
The present invention is solved its technical problem and realized using following technical scheme.
The present invention proposes a kind of pharmaceutical composition for treating cranial vascular disease, and it includes the first bulk drug, the first bulk drug Including:The bush of 14-16 parts by weight;The red sage root of 14-16 parts by weight;The leech of 4-6 parts by weight;The earthworm of 9-12 parts by weight;With And 6-9 parts by weight process naze.
The present invention proposes a kind of preparation method of aforementioned pharmaceutical compositions, the first raw material medicaments in part by weight number is mixed, powder It is broken, decoction at least 20 minutes is mixed with water, obtains filtrate.
The beneficial effect of the pharmaceutical composition for the treatment of cranial vascular disease of the embodiment of the present invention and preparation method thereof is:
By the rational proportion between each drug component, each herbal medicine synergy, have qi and activate blood circulation, by blood stasis and smoothing collaterals, The functions such as phlegm reduction of blood circulation promoting, ceases wind reduction blood fat, fundamentally effectively treat cranial vascular disease, especially treat and prevent cerebral infarction, The diseases such as cerebral hemorrhage brain, vascular atherosclerosis and cerebral thrombus, and prevent the pain caused by above-mentioned illness, headache, insomnia, dizzy Complications or the sequelae such as dizzy, cardiac and cerebral blood supply insufficiency.
The preparation method is simply controllable, easy to operation, and large-scale production can be achieved.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase Product.
Have below to a kind of pharmaceutical composition for treating cranial vascular disease of the embodiment of the present invention and preparation method thereof Body explanation.
The present invention provides a kind of pharmaceutical composition for treating cranial vascular disease, and it includes the first bulk drug, wherein, first is former Material medicine includes:The bush of 14-16 parts by weight;The red sage root of 14-16 parts by weight;The leech of 4-6 parts by weight;The ground of 9-12 parts by weight Dragon;And 6-9 parts by weight process naze, by the reasonable compatibility of each component in the first bulk drug, each herbal medicine synergy, tool There is qi and activate blood circulation, reduce the functions such as blood fat by blood stasis and smoothing collaterals, phlegm reduction of blood circulation promoting, ceases wind, effectively treat cranial vascular disease, especially treat With the disease such as prevention cerebral infarction, cerebral hemorrhage brain, vascular atherosclerosis and cerebral thrombus, and prevent the pain caused by above-mentioned illness, Complications or the sequelae such as headache, insomnia, dizziness, cardiac and cerebral blood supply insufficiency.
Wherein, bush, nature and flavor:It is sweet, salty, put down, thoughts of returning home warp, Liver Channel, the spleen channel, there is promoting circulation of blood, broken stasis of blood, detumescence, the work(of analgesic Effect.The red sage root, nature and flavor:Bitter, it is slightly cold, the thoughts of returning home, Liver Channel, there is promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, the work(of cool blood to disappear carbuncle Effect.Leech, taste is salty, puts down, and enter liver, bladder two pass through, and has treatment apoplexy, hypertension, the clear stasis of blood, amenorrhoea, traumatic injury and other effects, closely Year new discovery leech preparation has special efficacy in preventing and treating cranial vascular disease and anticancer aspect.Earthworm, nature and flavor:Taste is salty;It is cold in nature, Return liver, Spleen, bladder warp, have a heat-clearing, soothing the liver, Zhichuan, the effect of dredging collateral, promoting blood circulation and removing blood stasis, prophylactic treatment cranial vascular disease.Naze is processed, is had There is detumescence to suppurate, scattered silt dredging collateral, stimulate the menstrual flow, lower breast, invigorating blood circulation analgesia.Ulcer sore swells are controlled, wind-cold-dampness arthralgia, Amenorrhea, alactation, are stopped Blood, disease scab gather the effect of.
It is highly preferred that the first bulk drug includes:The bush of 15 parts by weight;The red sage root of 15 parts by weight;The leech of 6 parts by weight; The earthworm of 10 parts by weight;And 8 parts by weight process naze, under the conditions of this ratio, qi and activate blood circulation, by blood stasis and smoothing collaterals, phlegm reduction of blood circulation promoting, breath Wind reduces the functional effects such as blood fat more preferably.
Because cranial vascular disease is often with general weakness, it is preferred that the first bulk drug also includes the Huang of 4-6 parts by weight Stilbene, effectively treat or alleviate powerless while effectively treating cranial vascular disease.It is highly preferred that the first bulk drug also includes 5 weight The Radix Astragali of part, effective invigorating qi for strengthening superficies, myogenic.Wherein, the Radix Astragali, nature and flavor:It is sweet, temperature, return lung, the spleen channel, there is invigorating qi for strengthening superficies, eliminating toxic row Purulence, diuresis, the effect of myogenic.
Preferably, the first bulk drug also includes the root of bidentate achyranthes of 4-6 parts by weight, the parasitism of 7-8 parts by weight, effectively remove obstruction in channels to relieve pain, Scattered blood stasis, strengthening the bones and muscles, effectively enhancing treatment or the symptom of alleviation soreness of waist and knee joint and flaccidity and weakness of the lower limbs, with remaining component reasonable compatibility Nourishing liver kidney, strengthening the bones and muscles etc., effectively treatment or alleviate the lower limb symptom such as again.It is highly preferred that the first bulk drug includes posting for 7 parts by weight It is raw, and the root of bidentate achyranthes of 5 parts by weight, treat or the symptom of alleviation soreness of waist and knee joint and flaccidity and weakness of the lower limbs is better.Wherein, the root of bidentate achyranthes, Nature and flavor:Hardship, acid, put down, enter liver and kidney channel, there is filling liver kidney, strengthening the bones and muscles, the effect of invigorate blood circulation.Parasitism is Chinese medicine mistletoe Alias, it is bitter in taste;It is sweet;It is mild-natured, Return liver;Kidney channel, have and control filling liver kidney;Strengthening the bones and muscles;The effect of wind-damp dispelling.
Preferably, the first bulk drug also includes the earthworm of 8-11 parts by weight, the calamus of 11-13 parts by weight, 9-11 parts by weight Bombys batryticatus, the cicada slough of 9-11 parts by weight, and the semen brassicae of 9-11 parts by weight, effectively treatment or alleviate because cranial vascular disease is led Situations such as slurred speech of cause, apoplexy.
Wherein, the traditional Chinese medical science thinks that the slurred speech that apoplexy and apoplexy trigger is due to that qi and blood is inverse disorderly, produce wind, fire, phlegm, The stasis of blood, cause to cause brains nerve damage outside the resistance of brain vessle-Bi symptom-complex or the excessive brain arteries and veins of blood and fall ill.And earthworm, nature and flavor:Taste is salty;It is cold in nature, return Liver, spleen, bladder warp, have a heat-clearing, soothing the liver, Zhichuan, the effect of dredging collateral, promoting blood circulation and removing blood stasis, prophylactic treatment cranial vascular disease.Herein Calamus can be Rhizoma Anemones Altaicae, grass-leaved sweetflag or rhizoma calami, be respectively provided with the effect of reducing phlegm by resuscitation, a surname's gas are by phlegm.Bombys batryticatus, it is the other of stiff silkworm Claim, nature and flavor:It is salty, pungent, put down, Return liver, lung, stomach, can expel endogenous wind to relieve convulsion, reducing phlegm and resolving masses.Cicada slough, sweet, salty, cool in nature, return lung, liver Through there is dispelling wind and heat from the body, relieving sore-throat opens sound, the effect of Inflammation Zhijing.Semen brassicae is warm-natured, and rich gas is sharp, enters lung, stomach, can sharp gas Slit phlegm, warming spleen and stomach for dispelling cold, remove obstruction in channels to relieve pain.By the cooperation of above-mentioned each component, effective sharp gas slit phlegm, dispelling wind and heat from the body, promoting blood circulation and removing blood stasis, change Phlegm dissipating bind etc., coordinate with remaining component, effectively treatment or alleviation is due to the feelings such as slurred speech, apoplexy caused by cranial vascular disease Condition.
It is highly preferred that the first bulk drug also includes the earthworm of 10 parts by weight, the calamus of 12 parts by weight, the bombys batryticatus of 10 parts by weight The cicada slough of 10 parts by weight, and the semen brassicae of 10 parts by weight, sharp gas slit phlegm, dispelling wind and heat from the body, promoting blood circulation and removing blood stasis, reducing phlegm and resolving masses and other effects More preferably.
Preferably, the first bulk drug also includes the cassia seed of 9-11 parts by weight, it is highly preferred that the first bulk drug also includes 10 The cassia seed of parts by weight, effectively alleviate or treat dizzy caused by heart and brain blood backbone's disease.Wherein, cassia seed bitter, it is sweet, It is salty, cold nature, enter liver, kidney, large intestine channel;Relax bowel, clear liver and improve vision, sharp water defaecation, there is laxative action, reducing blood pressure and blood fat.
In order to further enhance the therapeutic effect of pharmaceutical composition, it is preferable that pharmaceutical composition also includes the second bulk drug, Specifically, the second bulk drug includes:The Radix Angelicae Sinensis of 14-16 parts by weight;The full worm of 9-10 parts by weight;The peach kernel of 9-11 parts by weight;9- The safflower of 11 parts by weight;The leech of 7-8 parts by weight;The centipede of 3-5 parts by weight;The dried orange peel of 9-10 parts by weight;11-13 parts by weight The tuber of pinellia;The blue or green chlorite schist of 28-32 parts by weight, the Tabasheer of 17-20 parts by weight;The bamboo juice of 17-20 parts by weight;14-16 parts by weight Reticulate millettia.Further effective promoting blood circulation, blood stasis removing analgesic, dredging collateral, dissipating bind, further enhance therapeutic effect.
Wherein, Radix Angelicae Sinensis, nature and flavor:Sweet, acrid, warm, Return liver, the heart, the spleen channel, there is replenishing and activating blood, menstruction regulating and pain relieving, relax bowel Effect.Full worm, also known as scorpio, nature and flavor:It is pungent, put down;Poisonous, return liver warp has antispastic cramp and relieves dizziness, anti-inflammatory and attacked poison, the work(removed obstruction in channels to relieve pain Effect.Peach kernel, nature and flavor:Bitter sweet, put down, nontoxic, the thoughts of returning home, liver, large intestine, lung, the spleen channel, there is the effect of blood-breaking row stasis of blood, moisturize laxation.It is red Flower, warm-natured, acrid flavour, invigorate blood circulation, blood stasis removing analgesic.Leech, taste is salty, puts down, and enter liver, bladder two pass through, and has treatment apoplexy, high blood Pressure, the clear stasis of blood, amenorrhoea, traumatic injury and other effects, in recent years new discovery leech preparation preventing and treating cranial vascular disease and anticancer aspect have Special efficacy.Centipede, nature and flavor:It is pungent, temperature;It is poisonous;Return liver warp, there is ceases wind antispastic, dispersing pathogen accumulation, the effect of removing obstruction in channels to relieve pain.Dried orange peel, property Taste:It is arduous, temperature, enter spleen, lung channel, there is the effect of regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm;The tuber of pinellia, there is blood stasis removing analgesic;Removing toxicity for detumescence Effect.Blue or green chlorite schist, property is sweet, salty, flat, falls gas under phlegm.Tabasheer, nature and flavor:It is sweet, tremble with fear, thoughts of returning home warp, Liver Channel, there is dispelling wind and eliminating dampness, work The effect of easypro warp of blood, cough-relieving.Bamboo juice, it is sweet in flavor and cold in property, the fire for the lung stomach that can clear away heart-fire, there is slit phlegm to moisturize, the effect of arresting convulsion.Reticulate millettia, property Taste:Hardship, micro-sweet;It is warm-natured.The thoughts of returning home, the spleen channel, dissipate gas, promoting blood circulation, relaxing muscles and tendons, active and other effects.
It is highly preferred that the second bulk drug includes:The Radix Angelicae Sinensis of 15 parts by weight;The full worm of 10 parts by weight;The peach kernel of 10 parts by weight; The safflower of 10 parts by weight;The leech of 8 parts by weight;The centipede of 5 parts by weight;The dried orange peel of 10 parts by weight;The tuber of pinellia of 12 parts by weight;30 weights Measure the blue or green chlorite schist of part, the Tabasheer of 18 parts by weight;The bamboo juice of 18 parts by weight;The reticulate millettia of 15 parts by weight.Further effectively invigorate blood circulation, Blood stasis removing analgesic, dredging collateral, dissipating bind, further enhance therapeutic effect.
Preferably, the formulation of pharmaceutical composition is decoction, oral solutions, granule, pill, powder, syrup or capsule Any one in agent.For example, the formulation of pharmaceutical composition is decoction, or pill, it can also be capsule.
The present invention also provides the preparation method of aforementioned pharmaceutical compositions, and the first bulk drug is mixed, and crushes, and mixes and decocts with water Boil at least 20 minutes, obtain filtrate.
When aforementioned pharmaceutical compositions contain the second raw material, first the second raw materials by weight portion of raw material is mixed, crushed, Decoction at least 20 minutes is mixed with water, obtains filtrate.
Wherein, the preferred mesh sieve of mistake 20 after above-mentioned crushing, then screenings is decocted at least 20 minutes, such as 30 minutes, 50 points Clock, 60 minutes etc., obtain filtrate.
Preferably, screenings is mixed with water, after soaking 20-40 minutes, then decocted, when being easy to save follow-up decoct Between.Wherein, decocting once to be carried out, and can also be carried out step by step, for example, decocting for the first time, filtered, obtained the first filtrate and first Filter residue, the first filter residue continue to decoct, and obtain the second filtrate, merge the first filtrate and the second filtrate etc., are not specifically limited herein.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of pharmaceutical composition for treating cranial vascular disease, it is prepared by following methods:
First bulk drug is mixed, crushed, decoction 40 minutes is mixed with water, obtains filtrate.
Wherein, the first bulk drug includes:The bush of 15 parts by weight;The red sage root of 15 parts by weight;The leech of 6 parts by weight;10 weights Measure the earthworm of part;And 8 parts by weight process naze.
Embodiment 2
A kind of pharmaceutical composition for treating cranial vascular disease, it is prepared by following methods:
First bulk drug is mixed, crushed, decoction 20 minutes is mixed with water, obtains filtrate.
Wherein, the first bulk drug includes:The bush of 14 parts by weight;The red sage root of 16 parts by weight;The leech of 6 parts by weight;9 weight The earthworm of part;The Radix Astragali of 5 parts by weight;And 8 parts by weight process naze.
Embodiment 3
A kind of pharmaceutical composition for treating cranial vascular disease, after it is mixed by the first raw material, according to existing technology and Equipment is made as granule.
Wherein, the first bulk drug includes:The bush of 16 parts by weight;The red sage root of 14 parts by weight;The leech of 4 parts by weight;12 weights Measure the earthworm of part;The root of bidentate achyranthes of 5 parts by weight, the parasitism of 8 parts by weight;And 7 parts by weight process naze.
Embodiment 4
A kind of pharmaceutical composition for treating cranial vascular disease, it is made as by the first raw material according to existing technology and equipment Pill.
Wherein, the first bulk drug includes:The bush of 15 parts by weight;The red sage root of 15 parts by weight;The leech of 5 parts by weight;20 weights Measure the earthworm of part;The calamus of 12 parts by weight, the bombys batryticatus of 10 parts by weight, the cicada slough of 10 parts by weight, the semen brassicae of 10 parts by weight, and 8 parts by weight process naze.
Embodiment 5
A kind of pharmaceutical composition for treating cranial vascular disease, it is prepared by following methods:
First bulk drug is mixed with the second bulk drug, crushed, decoction 50 minutes is mixed with water, obtains filtrate.
Wherein, the first bulk drug includes:The bush of 15 parts by weight;The red sage root of 15 parts by weight;The leech of 6 parts by weight;10 weights Measure the earthworm of part;And 8 parts by weight process naze.
Second bulk drug includes:The Radix Angelicae Sinensis of 15 parts by weight;The full worm of 10 parts by weight;The peach kernel of 10 parts by weight;10 parts by weight Safflower;The leech of 8 parts by weight;The centipede of 5 parts by weight;The dried orange peel of 10 parts by weight;The tuber of pinellia of 12 parts by weight;The green grass or young crops of 30 parts by weight Chlorite schist, the Tabasheer of 18 parts by weight;The bamboo juice of 18 parts by weight;And 15 parts by weight reticulate millettia.
Embodiment 6
A kind of pharmaceutical composition for treating cranial vascular disease, after it is mixed by the first raw material and the second raw material, according to existing Technology and equipment be made as pill.
First bulk drug includes:The bush of 15 parts by weight;The red sage root of 15 parts by weight;The leech of 5 parts by weight;10 parts by weight Earthworm;The root of bidentate achyranthes of 5 parts by weight;The parasitism of 7 parts by weight;And 8 parts by weight process naze.
Second bulk drug includes:The Radix Angelicae Sinensis of 14 parts by weight;The full worm of 9 parts by weight;The peach kernel of 9 parts by weight;9 parts by weight it is red Flower;The leech of 7 parts by weight;The centipede of 3 parts by weight;The dried orange peel of 9 parts by weight;The tuber of pinellia of 11 parts by weight;The blue or green chlorite schist of 28 parts by weight, The Tabasheer of 17 parts by weight;The bamboo juice of 17 parts by weight;And 14 parts by weight reticulate millettia.
Embodiment 7
A kind of pharmaceutical composition for treating cranial vascular disease, after it is mixed by the first raw material and the second raw material, according to existing Technology and equipment be made as powder.
First bulk drug includes:The red sage root of the parts by weight of bush 15 of 15 parts by weight;The leech of 5 parts by weight;10 parts by weight Earthworm;The Radix Astragali of 6 parts by weight;And 9 parts by weight process naze.
Second bulk drug includes:The Radix Angelicae Sinensis of 16 parts by weight;The full worm of 10 parts by weight;The peach kernel of 11 parts by weight;11 parts by weight Safflower;The leech of 8 parts by weight;The centipede of 5 parts by weight;The dried orange peel of 10 parts by weight;The tuber of pinellia of 13 parts by weight;The green grass or young crops of 32 parts by weight Chlorite schist, the Tabasheer of 18 parts by weight;The bamboo juice of 20 parts by weight;And 16 parts by weight reticulate millettia.
Embodiment 8
A kind of pharmaceutical composition for treating cranial vascular disease, its mixed by the first raw material and the second raw material after according to existing Technology and equipment are made as oral solutions.
First bulk drug includes:The bush of 16 parts by weight;The red sage root of 14 parts by weight;The leech of 6 parts by weight;11 parts by weight Earthworm;The Radix Astragali of 6 parts by weight;And 8 parts by weight process naze.
Second bulk drug includes:The Radix Angelicae Sinensis of 15 parts by weight;The full worm of 10 parts by weight;The peach kernel of 10 parts by weight;11 parts by weight Safflower;The leech of 7 parts by weight;The centipede of 3 parts by weight;The dried orange peel of 10 parts by weight;The tuber of pinellia of 11 parts by weight;The green grass or young crops of 29 parts by weight Chlorite schist, the Tabasheer of 18 parts by weight;The bamboo juice of 18 parts by weight;And 15 parts by weight reticulate millettia.
Test example
Embodiment 1-8 is repeated, the pharmaceutical composition of enough treatment cranial vascular diseases is made.Started successively in 2016 (men and women is than 1 by patient 50 of the selection with cranial vascular disease:1), using treatment cerebrovascular disease made from 1-8 of the embodiment of the present invention The pharmaceutical composition of disease, wherein, the pharmaceutical composition that embodiment 1-8 is provided is daily three times.
Empirical tests, 76% patient is 1 month after the pharmaceutical composition for the treatment of cranial vascular disease provided by the invention is taken Afterwards, cerebral infarction, cerebral hemorrhage and its complication etc. improve, and 85% patient is averagely taking treatment cerebrovascular disease provided by the invention After 2.5 months, cerebral infarction, cerebral hemorrhage and its complication etc. are obviously improved or cured the pharmaceutical composition of disease.It is exemplified below 2 tools Body patient is described in detail:
1. Mr. Wang, female.
Extremity numbness is felt, is had a dizzy spell suddenly when afternoon nap is got up, mind is still clear, and gradual left hand acts ineffective, ability to speak Unclear, right side facial paralysis, tongue can not be stretched, mouth salivation, dysphagia, aphasia from apoplexy, blood pressure 190/90mmHg.Be admitted to hospital examine for:Lacuna Property cerebral infarction.
Tcm diagnosis is stroke in convalescent stage, card category Qi deficiency blood stasis type, is taken after pharmaceutical composition provided by the invention 1 month Look is slightly shaken afterwards, and salivation is reduced, and facial paralysis tongue improves by force, and can prevaricate half language, and function of deglutition recovers.After dosage slightly increases and decreases, continue Take to second month, tongue is secretly significantly improved, and all diseases are calmed down.
2. certain, male slowly.
2 years hemorrhages of forebrain, through rescuing Survive the perils of life, but it is stuttering to leave the strong language of tongue, facial paralysis, left limb paralysis, Multi-treatment DeGrain.Existing bicker right avertence, the strong language of tongue is stuttering, and left limb can not praise activity, dizzy weak, bicker stream Saliva, extremity numbness, light purplish tongue tongue is thin white, and an arteries and veins left side is heavy, and the right side is heavy thin powerless, belongs to apoplexy sequelae, is Qi deficiency blood stasis type, takes After one month, facial paralysis mitigates pharmaceutical composition provided by the invention, can answer simple question, left side upper and lower extremities can be raised Moved from bed surface.After dosage slightly increases and decreases, continue with taking to after the 2.5th month, all disease disappearances, can out-of-bed activity, take care of oneself.
To sum up, pharmaceutical composition for the treatment of cranial vascular disease of the embodiment of the present invention and preparation method thereof, there is QI invigorating to live Blood, by blood stasis and smoothing collaterals, phlegm reduction of blood circulation promoting, ceases wind blood fat and other effects is reduced, effectively treat or prevent cerebral infarction, cerebral hemorrhage brain, artery The disease such as hardening and cerebral thrombus, and prevent pain, headache, insomnia, dizziness, cardiac and cerebral blood supply insufficiency etc. caused by above-mentioned illness Complications or sequelae.
Embodiments described above is part of the embodiment of the present invention, rather than whole embodiments.The reality of the present invention The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made Every other embodiment, belongs to the scope of protection of the invention.

Claims (10)

  1. A kind of 1. pharmaceutical composition for treating cranial vascular disease, it is characterised in that described pharmaceutical composition includes the first bulk drug, First bulk drug includes:The bush of 14-16 parts by weight;The red sage root of 14-16 parts by weight;The leech of 4-6 parts by weight;9-12 weights Measure the earthworm of part;And 6-9 parts by weight process naze.
  2. 2. pharmaceutical composition according to claim 1, it is characterised in that first bulk drug includes:15 parts by weight The bush;The red sage root of 15 parts by weight;The leech of 6 parts by weight;The earthworm of 10 parts by weight;And 8 parts by weight Described process naze.
  3. 3. pharmaceutical composition according to claim 1, it is characterised in that first bulk drug also includes 4-6 parts by weight The Radix Astragali.
  4. 4. pharmaceutical composition according to claim 1, it is characterised in that first bulk drug also includes 4-6 parts by weight The root of bidentate achyranthes, the parasitism of 7-8 parts by weight.
  5. 5. pharmaceutical composition according to claim 1, it is characterised in that first bulk drug also includes 8-11 parts by weight Earthworm, the calamus of 11-13 parts by weight, the bombys batryticatus of 9-11 parts by weight, the cicada slough of 9-11 parts by weight, and 9-11 parts by weight is white Mustard seed.
  6. 6. pharmaceutical composition according to claim 1, it is characterised in that first bulk drug also includes 9-11 parts by weight Cassia seed.
  7. 7. pharmaceutical composition according to claim 1, it is characterised in that described pharmaceutical composition also includes the second raw material Medicine, second bulk drug include:The Radix Angelicae Sinensis of 14-16 parts by weight;The full worm of 9-10 parts by weight;The peach kernel of 9-11 parts by weight;9- The safflower of 11 parts by weight;The leech of 7-8 parts by weight;The centipede of 3-5 parts by weight;The dried orange peel of 9-10 parts by weight;11-13 parts by weight The tuber of pinellia;The blue or green chlorite schist of 28-32 parts by weight, the Tabasheer of 17-20 parts by weight;The bamboo juice of 17-20 parts by weight;14-16 parts by weight Reticulate millettia.
  8. 8. pharmaceutical composition according to claim 7, it is characterised in that second bulk drug includes:15 parts by weight The Radix Angelicae Sinensis;The full worm of 10 parts by weight;The peach kernel of 10 parts by weight;The safflower of 10 parts by weight;The institute of 8 parts by weight State leech;The centipede of 5 parts by weight;The dried orange peel of 10 parts by weight;The tuber of pinellia of 12 parts by weight;30 parts by weight it is described Blue or green chlorite schist, the Tabasheer of 18 parts by weight;The bamboo juice of 18 parts by weight;The reticulate millettia of 15 parts by weight.
  9. 9. according to the pharmaceutical composition described in claim 1-8 any one, it is characterised in that the formulation of described pharmaceutical composition For any one in decoction, oral solutions, granule, pill, powder, syrup or capsule.
  10. 10. the preparation method of pharmaceutical composition as claimed in claim 1, it is characterised in that first bulk drug is mixed, Crush, decoction at least 20 minutes is mixed with water, obtains filtrate.
CN201710604712.8A 2017-07-24 2017-07-24 A kind of pharmaceutical composition for treating cranial vascular disease and preparation method thereof Pending CN107334815A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114390927A (en) * 2019-09-17 2022-04-22 鲁南制药集团股份有限公司 New application of traditional Chinese medicine composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114390927A (en) * 2019-09-17 2022-04-22 鲁南制药集团股份有限公司 New application of traditional Chinese medicine composition

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