CN107308372A - It is a kind of to treat medicine of facial nerve paralysis and preparation method thereof - Google Patents
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Abstract
The present invention discloses a kind of medicine for treating facial nerve paralysis, including following components：6~15 parts of the Radix Astragali, 6~15 parts of Radix Codonopsis, 3~10 parts of vomiting nut, 3~10 parts of scorpio, 3~10 parts of stiff silkworm, 3~10 parts of centipede, 4~8 parts of lopseed, 3~15 parts of levisticum, 4~23 parts of ground beetle, 5~18 parts of semen momordicae, 6~8 parts of Semen Lablab Album, 7~18 parts of dark plum, 5~12 parts of loguat leaf, 3~5 parts of Semen Cuscutae, 7~18 parts of witloof, 13~28 parts of the Fen, Common St.Paulswort Herbs of the fruit of Chinese magnoliavine 1~5,3~18 parts of cactus, 6~9 parts of rhizoma imperatae, 3~8 parts of the wind-weed, 9~14 parts of dragon Lei.The present invention is by the way that having dispersing blood stasis, the Chinese medicine of dispelling pathogenic wind and eliminating phlegm dredging collateral effect is effectively arranged in pairs or groups together, is nursed one's health and reached the purpose for the treatment of facial nerve paralysis.This formula herbs is easy to get, and preparation method is simple, and therapeutic effect is preferable.
Description
Technical field
The present invention relates to the field of Chinese medicines, more precisely a kind of medicine for being used to treat facial nerve paralysis.
Background technology
Facial nerve paralysis, also referred to as facial neuritis, are commonly called as facial paralysis, and its symptom is patient's deviation of the mouth with numbness and paralysis after illness, mouth
Angular flux saliva, facial expression is strange stiff, can also produce sequelae after some patient's treatments, facial spasm, some patient's meetings occurs
There is trigeminal neuralgia, the of short duration recurrent exerbation in trigeminal neuralgia distributed area causes patient's tear sample pain.Facial nerve paralysis
The cause of disease it is complicated, treatment difficulty is big.Treatment facial nerve paralysis is global problem at present.Performed the operation using doctor trained in Western medicine, Huan Zhebei
Groan, using Chinese medicine acupuncture slowly effect, patient suffering is big, and cure rate is not high.Tool estimation, the whole world has face nerve at present
Patient is benumbed more than 10,000,000, patient almost can occur from child to old man in all age brackets, and treat face nerve
The method of paralysis is not ideal with medicine.
The content of the invention
It is an object of the invention to provide a kind of medicine for treating facial nerve paralysis and preparation method thereof, it can solve existing
There is the disadvantages mentioned above in technology.
Astragalus,《Compendium of Materia Medica》Claim the Radix Astragali,《Sheng Nong's herbal classic》Title wears crushed grain.《Mingyi Bielu》Title wears mulberry, only mulberry, another name for Sichuan Province fat,
Hundred.《Haigoushen》Proclaim oneself king grandson.Li Shizhen (1518-1593 A.D.) says that over sixty years of age is the long meaning, and astragalus color Huang is the length of tonic, therefore named.The present is commonly called as the Radix Astragali.
" Radix Astragali, tonifying lung invigorating the spleen, defend arrest sweating in fact, and wind dispelling transports the medicine of poison.Therefore the people of the deficiency of yang, spontaneous perspiration frequency comes, and is exterior deficiency and interspaces of skin and muscles being loose
, the Radix Astragali can defend and arrest sweating in fact；The card of typhoid fever, row is delivered and evil sweat does not go out, and is interior deficiency and weary in healthy tendency, the Radix Astragali can help
Tianjin is to help sweat；The disease of harmful wind, inclined invasion of vessels and brothers are not with person, and the Radix Astragali can flourish muscles and bones；Burst in the card of large carbuncle, purulence blood, yang-energy
Empty the Radix Astragali can be with myogenic meat, and the erosion of vulva can not rise without the person of holding back, and yang-energy is empty and unhealed, and the Radix Astragali can be with myogenic meat.”(《This
Grass, which converges, to be sayed》).
Radix Codonopsis is the conventional traditional tonic of China, and the Radix Codonopsis that ancient times are produced using Shanxi Shangdang area is top grade, with benefit
The effect of middle QI invigorating, strengthening spleen and tonifying lung.Modern study, Radix Codonopsis contains various saccharides, phenols, sterol, volatile oil, baicalein glucose
Glucoside, saponin and Alkaloid, make with strengthen immunity, expansion blood vessel, decompression, improvement microcirculation, enhancing hematopoiesis function etc.
With.In addition leucocyte caused by chemotherapy radiotherapy is declined has castering action.But the stagnation of the circulation of vital energy, irascibility Sheng person disabling；Heresy contain and it is just not empty
Person is unsuitable.
Vomiting nut, it is bitter, tremble with fear, it is poisonous.①《Detailed outline》：" it is bitter, tremble with fear, it is poisonous.”②《Book on Chinese herbal medicine is original》：" bitter, trembles with fear, big poison.”
Return liver, spleen two are passed through.Cure mainly：1. remove obstruction in channels to relieve pain：With controlling rheumatoid arthritis stubborn or contraction.2, dispersing swelling and dissipating binds：With controlling, the wound stasis of blood is swollen to ache
Pain and ulcer sore pain.In recent years with a variety of cancerous swellings are controlled, there is certain curative effect.3. sequelae of infantile paralysis is treated, the protrasion of the lumbar intervertebral disci,
Trigeminal neuralgia, rheumatoid arthritis, traumatic injury, pain due to blood stasis, wind-cold-dampness arthralgia, general joint are arrested anxious, numb, cancerous swelling
Deng.Cure mainly throat numbness pain, swollen ulcer drug, wandering arthritis pain, fracture, facioplegia, myasthenia gravis.Usage and dosage takes orally：Big gun
Enter ball after system, dissipate, take day 0.3~0.6 gram (heavy dose of 0.9 gram).Suitable amount used externally, grinds and spreads, or immersion, vinegar mill, pan-fried oil coating,
Or endure cream and stick.
Scorpio, it is pungent, put down；It is poisonous.Return liver warp.Effect：Ceases wind antispastic, dispersing pathogen accumulation is removed obstruction in channels to relieve pain.Main syndrome：For
Child convulsion, tic spasm, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Stiff silkworm, alias flying worm, ginger silkworm.It is a kind of special product of comparison, it also known as the larva of a silkworm with batrytis are silkworm larvas in spinning
Cause infects muscardine and the lethal dry hardening polypide that falls ill, because its body surface gathers white hypha and conidium, likeness in form
One layer of tunica albuginea, it is therefore named, it is mainly used in convulsion, abscess of throat, submandibular lymph nodes is scorching, facioplegia, the disease such as pruitus
Disease.
Centipede, pungent, temperature；It is poisonous.Return liver warp.Ceases wind antispastic, dispersing pathogen accumulation is removed obstruction in channels to relieve pain.For child convulsion, tic convulsion
Contraction, middle air port is askew, hemiplegia, lockjaw, rheumatoid arthritis stubborn, sore, scrofula, venomous snake bite.
Lopseed, use all herbal medicine among the people is cured cold, traumatic injury, and carbuncle, eczema, scabies are controlled in external application.Root and leaf it is fresh
Juice or decocting liquid have strong toxicity to the larva of cabbage butterfly, housefly and Culex tritaeniorhynchus.Root is containing lopseed element
(phrymarolin) and leptostachyol acetic acid esters (leptostachyol acetate), the latter is insecticidal constituent.It is among the people to use complete
The pan-fried water of grass eliminates fly maggot and cabbage caterpillar.
Levisticum, pungent, hardship, tepor.Return liver, kidney, bladder warp.Cure mainly:Expelling wind and eliminating dampness；Eliminating cold to stop pain.For wind-cold-dampness arthralgia；Waist
Knee pain；Few the moon volt wind headache, dentalgia of having a headache.
Ground beetle, it is salty, tremble with fear；It is slightly poisonous.Return liver warp.【Function is with curing mainly】Broken stasis of blood blood, continuous muscles and bones.For injured bone, hemostasis
Amenorrhea, abdominal mass lump in the abdomen.《This warp》" main trusted subordinate's fever and chills are washed, blood product abdominal mass, break heavily fortified point, lower blood is closed "《About property opinion》" Zhi Yueshui is not
Adjust, broken accumulation of bleeding.”《Amplification on Materia Medica》" alactation, grinds one piece, water is hemizygous, filtering clothes " row postpartum blood product, injured extravasated blood,
Tongue weight, swollen and rigid tongue, aphtha, the abdominal pain in children morbid night crying of babies.”
Semen momordicae, for dispersing swelling and dissipating binds, toxic removing.Control carbuncle swells, furunculosis, scrofula, hemorrhoid, nameless sores or boils, tinea sore, rheumatism numbness
Bitterly, muscle arteries and veins contraction.①《Japan hanako materia medica》：Vinegar rub detumescence poison.②《Kaibao Bencao》：Main injured, the swollen malignant sore of the knot that disappears, myogenic, only
Pain in the back, except acne acid anhydride is rubbed, married woman's acute mastitis, anus swells and ache.③《Detailed outline》：Control infantile malnutrition due to digestive disturbances or intestinalparasites lump in the abdomen, profit large intestine rush down dysentery, hemorrhoid knurl scrofula.④
《Essentials of Materia Medica》：Purge heat, sore is controlled in external application.Profit large intestine, controls rush down dysentery infantile malnutrition due to digestive disturbances or intestinalparasites, scrofula sore hemorrhoid, acute mastitis, freshwater mussel poison.Detumescence is chased after poison, and myogenic is removed
Acid anhydride.⑤《Book on Chinese herbal medicine asks former》：Control all cold-dampness it is hot and suffocating and be gout paralysis, migratory arthralgia, scabies faint, tinea pedis, contraction disease, crane knee.
Semen Lablab Album, what bright Li Shizhen (1518-1593 A.D.) write《Compendium of Materia Medica》Say:" taking duricrust Semen Lablab Album, gross weight is fried, and is used as medicine ", " duricrust is white
French beans, its son enriches, and Bai Erwei is yellow, and its gas raw meat is fragrant, and its is warm-natured flat, obtains neutralization, the paddy of spleen.The lunar qi leel of people, tonneau three
Jiao, can change and drop turbid clearly, therefore specially control the disease of Middle Palace, relieve summer heat and dehumidify and detoxify.Its soft shell and black magpie color person, its slightly cool in nature, but can
For food, taste are also adjusted." Pharmacopoeia Commission of the Ministry of Public Health compiles《Chinese Pharmacopoeia》Also say:Semen Lablab Album " strengthening the spleen and stomach, clear summer-heat and damp.For spleen
Stomach weakness, summer heat damp diarrhea, leukorrhea ".In a word, Semen Lablab Album is precious, its fruit (Semen Lablab Album), pericarp (testa dolichoris), flower, leaf all over the body
Can people's medicine.Its nature and flavor is sweet micro- wet, enters the warp of taste two, there is tonifying spleen and stomach, and middle dampness elimination, and the effect for removing toxic substances of relieving summer heat cures mainly taste empty
Weak, diarrhea, vomiting, accumulate in summer-heat and damp, abdominal distention, the inferior disease of red leukorrhea, and can relieving alcoholism.
Dark plum,【Nature and flavor】It is sour, puckery, put down.【Channel tropism】Return liver, spleen, lung, large intestine channel.【Major function】Astringe the lung, puckery intestines promote the production of body fluid,
Claming ascaris.For chronic cough of deficiency lung；Abnormal heat polydipsia；Chronic malaria；Chronic diarrhea；Dysentery；Have blood in stool；Hematuria；Metrorrhagia；The ascariasis of biliary tract is suffered from abdominal pain；Vomiting；Hookworm
Disease.
Loguat leaf, it is bitter, it is slightly cold.《Do not record》：Bitter, puts down, nontoxic.《Haigoushen》：It is sweet.《The southern regions of the Yunnan Province book on Chinese herbal medicine》：Cold nature, taste
Toil.Return lung, stomach.《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" enter lung."《Bencao Jingshu》：" lunar, Foot yangming Channel of starting with."《Herbal solutions》："
Enter lung meridian, the heart channel of Hand-Shaoyin."
Semen Cuscutae, Xin Gan is put down.《This warp》：" it is pungent, put down."《Do not record》：" it is sweet, it is nontoxic."《Book on Chinese herbal medicine is just》；" acrid-sweet flavor, gas
Tepor."【Channel tropism】Enter liver and kidney channel.《Bencao Jingshu》：" spleen, kidney, liver three pass through."《Book on Chinese herbal medicine is newly organized》：" enter the heart, liver, the warp of kidney three."
【Major function】Filling liver kidney, benefiting quintessence, improving eyesight.Soreness of waist and knee joint is controlled, passes out semen, quenches one's thirst, dripping urination, mesh is dark.
Witloof, bitter；It is cold in nature.Effect is clearing heat and detoxicating；Inducing diuresis to remove edema.Cure mainly jaundice with damp-heat pathogen；Nephritic dropsy；Gastral cavilty is swollen
Bitterly；Poor appetite.
The fruit of Chinese magnoliavine, is astringed the lung, and nourshing kidney is promoted the production of body fluid, and receives sweat, puckery essence.Control the deficiency syndrome of the lung to breath with cough, thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin
It is thin, emission, protracted dysentery and diarrhea.(1) astringe the lung to stop cough：Void for deficiency of both the lung and kidney is coughed, panted, and is often shared with kidney-reinforcing drug.(2) it is puckery
Smart antidiarrheal：For passing out semen, chronic diarrhea.Control seminal emission and often match somebody with somebody mantis egg-case, calcined Dragon's bone；Control chronic diarrhea and often match somebody with somebody nutmeg, Gorgon fruit.(3) promote the production of body fluid and hold back
Sweat：Dry thirsty, night sweat for YIN-fluid being insufficient, often with the tuber of dwarf lilyturf, raw oyster.(4) shock of all qi and blood dissipation, collapse, all
It can be used with tonic.①《This warp》：Main QI invigorating, cough with dyspnea, the thin degree of internal lesion caused by overexertion, tonifying for the deficiency, Qiang Yin.
Common St.Paulswort Herb, function：Wind-damp dispelling, sharp joint, removing toxic substances.Cure mainly：For arthralgia pain due to rheumatism, powerless muscles and bones, soreness and weakness of waist and knees, four
Acroparalysis, hemiplegia, rubella wet sore.Usage and dosage：9-12 grams of consumption.Process：Impurity is removed, cleans, slightly moistens, segment, is done
It is dry.《Tang materia medica》：" main heat [worm of hideing], dysphoria can not be eaten." " main metal-inflicted wound, analgesic, disconnected blood, raw meat, except all malignant sores, disappears floating
It is swollen.”《Bencao Shiyi》：" main chronic malaria, Tan Shade, it is raw to smash strand juice clothes, obtain discharge phlegm；Also broken deposited spider is stung, worm silkworm stings, earwig is drowned
Sore.”《Kaibao Bencao》：" treat tiger fur and dog stings sore.”《Lv Cliff rocks book on Chinese herbal medicine》：" doctor collapses from physical exhaustion wind disease, and tendon and vessel is delayed weak.For end, wine is adjusted
Clothes.”《Product converge essence will》：" control apoplectic aphasia in silence, facial paralysis, when saliva spitting.Qi-restoratives, five viscera settling, piliation.Bright eyes, crow
Moustache is sent out, and strengthens biceps.”《Book on Chinese herbal medicine covers bamboo fish trap》：" heresy is in fashion in treating cruelly, deviation of the eye and mouth person is had immediate effect；Long excreting dampness numbness is controlled, the waist pin person of aching is different
Work(.”《Detailed outline》：" liver kidney general mood is controlled, quadriplegia, ostalgia knee is weak, all sores of rheumatism.”《The sward property of medicine is standby will》：" hemorrhoid are washed, are washed
Infantile malnutrition due to digestive disturbances or intestinalparasites goes to swell.”《The property of medicine is wanted in medical center bun》：" hard bone, row liver, dry spleen, reduce phlegm and internal heat.”《Classification is herbal》：" nourishing yin and nourishing blood." celestial being
The palm, not only can be with clearing heat and detoxicating, eliminating stasis to subdue swelling, benefiting stomach and stopping pain, antibechic.And for taste-blindness rate, acute dysentery,
Cough；Mumps is controlled in external application, and mastitis, carbuncle furuncle poison, hemorrhoid, snake bite, burn and scald has special efficacy.
Rhizoma imperatae, cool blood, hemostasis, heat-clearing, diuresis.Pyreticosis polydipsia is controlled, is spitted blood, bleeding from five sense organs or subcutaneous tissue, lung heat breathes heavily urgency, stomach energy hiccup drenches
Disease, difficult urination, oedema, jaundice.《This warp》：" main internal lesion caused by overexertion void is thin, tonifying middle-Jiao and Qi, except hemostasis, blood close fever and chills, diuresis."《Not
Record》：" lower five drench, and except objective heat is in stomach, quench the thirst, hard muscle, married woman's metrorrhagia."《Japan hanako materia medica》：" housewife's man month, through irregular, leads to
Blood vessels drench drip."《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" antiemetic blood, bleeding from five sense organs or subcutaneous tissue, control blood strangury, diuresis, only married woman's metrostaxis."《Detailed outline》：" antiemetic
It is defeated in battle all blood, typhoid fever hiccup, lung heat breathes heavily urgency, oedema, jaundice, relieving alcoholism."《This is through meeting original》：" control gas in regurgitation, five drench pain heat and
The dry purple of variola does not rise."《Animals and plants Folk medicine》：" control tinea pedis.".
The wind-weed, performance：It is bitter, sweet, cold.Return lung, stomach, kidney channel.Effect and application：Clearing heat-fire-- fever caused by exogenous pathogenic factors is controlled outside,
Hyperpyrexia polydipsia, inside controls cough with lung heat, and stomach energy is quenched one's thirst.Fluid dryness-- xeropulmonary cough；Dry constipation of intestines；Osteopyrexia and fever.【Usage is used
Amount】：Decoction, 6~12 grams..【Use attention】：Moral character Han Zhirun, there is purging and intestine lubricating action, therefore insufficiency of the spleen loose stool person should not use.Often with
Gypsum compatibility..【Differentiate medication】：Gypsum and the wind-weed energy clearing heat-fire, available treatment warm heat disease excessive heat in the system and lung heat are coughed
The card such as cough, but gypsum is longer than in removing summer-heat clear purging intense heat heat, focuses on clear purging the lung of pathogenic fire, stomach excess fire, lung heat cough and asthma, the toothache of stomach headache due to fire-evil are multi-purpose
Gypsum；It is longer than clear and rich, lung-heat type cough, interior hot hectic fever due to yin, the multiselect wind-weed of quenching one's thirst in wind-weed purging intense heat.
Imperial Lei, it is mild-natured, it is sweet, light.Return lung warp, stomach.【Effect and effect】Moisten the lung and relieve the cough, defaecation.Belong to preventing phlegm from forming and stopping coughing to put down
Breathe heavily the medicine for the treatment of cough and asthma classified under medicine.
The present invention uses following technical scheme：
A kind of medicine for treating facial nerve paralysis, including following components：6~15 parts of the Radix Astragali, 6~15 parts of Radix Codonopsis, Strychnos nux-vomica
3~10 parts of son, 3~10 parts of scorpio, 3~10 parts of stiff silkworm, 3~10 parts of centipede, 4~8 parts of lopseed, 3~15 parts of levisticum, ground beetle 4
~23 parts, 5~18 parts of semen momordicae, 6~8 parts of Semen Lablab Album, 7~18 parts of dark plum, 5~12 parts of loguat leaf, 3~5 parts of Semen Cuscutae, witloof
7~18 parts, 13~28 parts of the Fen, Common St.Paulswort Herbs of the fruit of Chinese magnoliavine 1~5,3~18 parts of cactus, 6~9 parts of rhizoma imperatae, 3~8 parts of the wind-weed, dragon
9~14 parts of Lei.
Including following components：It is 10 parts of the Radix Astragali, 9 parts of Radix Codonopsis, 6 parts of vomiting nut, 7 parts of scorpio, 9 parts of stiff silkworm, 6 parts of centipede, deep
5 parts of grass, 12 parts of levisticum, 18 parts of ground beetle, 15 parts of semen momordicae, 7 parts of Semen Lablab Album, 16 parts of dark plum, 9 parts of loguat leaf, 4 parts of Semen Cuscutae, chrysanthemum
13 parts of lettuce, 21 parts of the Fen, pig Xian of the fruit of Chinese magnoliavine 4,13 parts of cactus, 7 parts of rhizoma imperatae, 5 parts of the wind-weed, 12 parts of dragon Lei.
A kind of preparation method of the compound of facial nerve paralysis, comprises the following steps：
Wherein, nexine composition powder contains the extract of scorpio, stiff silkworm, centipede, ground beetle；
Outer layer composition contain the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf,
Semen Cuscutae, witloof, fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract.
The scorpio, stiff silkworm, centipede, the extract of ground beetle are prepared by the following method and obtained：
It is coarse powder by scorpio, stiff silkworm, centipede, broken ground beetle insects medicinal powder；The 8-12 times of water measured is added into coarse powder, is warming up to
58 DEG C, low-temperature dynamic is extracted or ultrasonic wave extraction 3 times, 6 hours every time, and extraction fluid and the dregs of a decoction add 8-12 into the dregs of a decoction
The water of times amount, is warming up to 80 DEG C, extracts 3 times, 2 hours every time, extraction fluid and the dregs of a decoction；Obtained by merging in above-mentioned steps
Extract solution, by concentrating, being dried to obtain insects medicament extract.
Take the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf, Semen Cuscutae, witloof,
Fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract co-grinding, are first extracted with 75% ethanol, and extract solution is returned
Ethanol is received, extract A is obtained, water will be added in fixed residue, is then extracted 3 times with ether shaking, 1 times of amount, merges second every time
Ether extract solution, is recovered under reduced pressure solvent and obtains extract B to dry, and extract A and extract B are merged, 10 times of medicinal material amounts are added water to,
12 hours are stood, filtering, filtrate is first rinsed with the water of 4 times of column volumes and set by processed good AB-8 large pore resin absorption column
Fat post discards water lotion to colourless, then with 70% alcohol flushing resin post of 5 times of column volumes, is spray-dried after eluent concentration,
Extract is made.
Nexine is combined to be respectively placed in outer layer composition diameter 1.5-2cm, thickness 2.5-3.5cm are pressed on forming machine
Ointment cake；Ointment cake is placed on the air-permeable paper adhesive plaster of 5.5cm × 5.5cm planes.
It is an advantage of the invention that：The present invention is by the way that having dispersing blood stasis, the Chinese medicine of dispelling pathogenic wind and eliminating phlegm dredging collateral effect is effectively
The purpose for the treatment of facial nerve paralysis is nursed one's health and reached to collocation together,.This formula herbs is easy to get, and preparation method is simple,
Therapeutic effect is preferable.
Embodiment
The embodiment of the present invention is further elucidated below：
A kind of medicine for treating facial nerve paralysis, including following components：It is 6 parts of the Radix Astragali, 6 parts of Radix Codonopsis, 3 parts of vomiting nut, complete
3 parts of scorpion, 3 parts of stiff silkworm, 3 parts of centipede, 4 parts of lopseed, 3 parts of levisticum, 4 parts of ground beetle, 5 parts of semen momordicae, 6 parts of Semen Lablab Album, 7 parts of dark plum,
5 parts of loguat leaf, 3 parts of Semen Cuscutae, 7 parts of witloof, 13 parts of the Fen, Common St.Paulswort Herbs of the fruit of Chinese magnoliavine 1,3 parts of cactus, 6 parts of rhizoma imperatae, 3 parts of the wind-weed,
Imperial 9 parts of Lei.
A kind of medicine for treating facial nerve paralysis, including following components：15 parts of the Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of vomiting nut,
10 parts of scorpio, 10 parts of stiff silkworm, 10 parts of centipede, 8 parts of lopseed, 15 parts of levisticum, 23 parts of ground beetle, 18 parts of semen momordicae, 8 parts of Semen Lablab Album,
18 parts of dark plum, 12 parts of loguat leaf, 5 parts of Semen Cuscutae, 18 parts of witloof, 28 parts of the Fen, Common St.Paulswort Herbs of the fruit of Chinese magnoliavine 5,18 parts of cactus, rhizoma imperatae
9 parts, 8 parts of the wind-weed, 14 parts of dragon Lei.
A kind of medicine for treating facial nerve paralysis, including following components：It is 10 parts of the Radix Astragali, 9 parts of Radix Codonopsis, 6 parts of vomiting nut, complete
7 parts of scorpion, 9 parts of stiff silkworm, 6 parts of centipede, 5 parts of lopseed, 12 parts of levisticum, 18 parts of ground beetle, 15 parts of semen momordicae, 7 parts of Semen Lablab Album, dark plum 16
Part, 9 parts of loguat leaf, 4 parts of Semen Cuscutae, 13 parts of witloof, 21 parts of the Fen, pig Xian of the fruit of Chinese magnoliavine 4,13 parts of cactus, 7 parts of rhizoma imperatae, the wind-weed 5
Part, 12 parts of dragon Lei.
A kind of preparation method for the medicine for treating facial nerve paralysis, comprises the following steps：
Wherein, nexine composition contains the extract of scorpio, stiff silkworm, centipede, ground beetle；
Outer layer composition contain the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf,
Semen Cuscutae, witloof, fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract.
Nexine is combined to be respectively placed in outer layer composition diameter 1.5-2cm, thickness 2.5-3.5cm are pressed on forming machine
Ointment cake；Ointment cake is placed on the air-permeable paper adhesive plaster of 5.5cm × 5.5cm planes.
The scorpio of the present invention, stiff silkworm, centipede, the extract of ground beetle are prepared by the following method and obtained：
It is coarse powder by scorpio, stiff silkworm, centipede, broken ground beetle insects medicinal powder；The 8-12 times of water measured is added into coarse powder, is warming up to
58 DEG C, low-temperature dynamic is extracted or ultrasonic wave extraction 3 times, 6 hours every time, and extraction fluid and the dregs of a decoction add 8-12 into the dregs of a decoction
The water of times amount, is warming up to 80 DEG C, extracts 3 times, 2 hours every time, extraction fluid and the dregs of a decoction；Obtained by merging in above-mentioned steps
Extract solution, by concentrating, being dried to obtain insects medicament extract.
The present invention the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf, Tu
Son, witloof, fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract are prepared by the following method and obtained：
Take the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf, Semen Cuscutae, witloof,
Fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract part co-grinding, are first extracted, extract solution with 75% ethanol
Ethanol is reclaimed, extract A is obtained, water will be added in fixed residue, is then extracted 3 times with ether shaking, 1 times of amount, merges every time
Ether extracted liquid, is recovered under reduced pressure solvent and obtains extract B to dry, and extract A and extract B are merged, 10 times of medicinal materials are added water to
Amount, stands 12 hours, filtering, and filtrate is first rinsed by processed good AB-8 large pore resin absorption columns with the water of 4 times of column volumes
Resin column discards water lotion, then with 70% alcohol flushing resin post of 5 times of column volumes, sprayed after eluent concentration dry to colourless
It is dry, extract is made.
Facial nerve paralysis is more, and because face experiences ailment said due to cold or exposure, obstruction of collateral caused by windphlegm, channels and collaterals are obstructed, and cause facial qi-blood circulating obstacle,
Channels and collaterals are not normal, therefore cause facial nerve paralysis, scorpio of the invention, stiff silkworm, centipede, ground beetle, for four kinds of insect medicines, with scorpio product
Property is walked to alter, and enters lung, the warp of spleen two, can search ailment said due to cold or exposure, saturating joint, degrading the channel are apt to walk to alter with ground beetle and centipede property, same return liver warp relieves dizziness, high fever, infantile convulsions, epilepsy, etc.
Only the key medicine of convulsion, has the good effect of removing obstruction in channels to relieve pain, and with the power of detoxicating and resolving a mass, lung is entered with energy wind-dispelling with stiff silkworm again
Resolving sputum, and nontoxic, and effect of reducing phlegm and resolving masses detumescence, it is the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, white flat
Beans, dark plum, loguat leaf, Semen Cuscutae, witloof, fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the extract of the wind-weed, carry out QI invigorating work
Blood, eliminating the phlegm dredging collateral, relieving convulsion and spasm, using cactus, rhizoma imperatae, the wind-weed to adjust in all medicines, are used by compatibility, are applicable to disadvantage
Each stage, the treatment of each card type, special effect possesses significantly advantage.
Pharmacological evaluation part：
The present invention treats patient diagnosed 150, wherein male 86 in the clinical observation of affiliated hospital of the college of traditional Chinese medicine of Shandong Province
Example, women 64 is observed through outpatient service, patch present invention effective percentage more than 98%, cure rate
More than 90%, now only select following several：
1. an xx, female, 18 years old, slight facial nerve paralysis, eye distortion of commissure when ill, patch is with after the patch of the present invention one 7 days
Bicker eye is crooked to disappear.
2. shut out xx, man, 56 years old, slight facial nerve paralysis, firmly hospital's treatment in 20 days is invalid, and patch uses the patch of the present invention three 18 days
Afterwards, deviation of the mouth with numbness and paralysis all disappears.
3. Liu xx, man, 65 years old, suffer from moderate facial nerve paralysis, tiltedly, the invention plaster 5 that loses money in a business is pasted eye bent finish, sick after 30 days
4. king xx, female, 24 years old, suffer from trigeminal neuralgia, right side head tear sample pain loses money in a business after inventing one hour, pain
Mitigate, pasted illness after a course for the treatment of and disappeared, illness do not occurred in half a year.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modifications, equivalent substitutions and improvements made within refreshing and principle etc., should be included in the scope of the protection.
Claims (6)
1. a kind of medicine for treating facial nerve paralysis, it is characterised in that including following components：6~15 parts of the Radix Astragali, Radix Codonopsis 6~
15 parts, 3~10 parts of vomiting nut, 3~10 parts of scorpio, 3~10 parts of stiff silkworm, 3~10 parts of centipede, 4~8 parts of lopseed, levisticum 3~15
Part, 4~23 parts of ground beetle, 5~18 parts of semen momordicae, 6~8 parts of Semen Lablab Album, 7~18 parts of dark plum, 5~12 parts of loguat leaf, Semen Cuscutae 3~
5 parts, 7~18 parts of witloof, 13~28 parts of the Fen, Common St.Paulswort Herbs of the fruit of Chinese magnoliavine 1~5,3~18 parts of cactus, 6~9 parts of rhizoma imperatae, the wind-weed 3
~8 parts, 9~14 parts of dragon Lei.
2. the medicine for the treatment of facial nerve paralysis according to claim 1, it is characterised in that including following components：The Radix Astragali
10 parts, 9 parts of Radix Codonopsis, 6 parts of vomiting nut, 7 parts of scorpio, 9 parts of stiff silkworm, 6 parts of centipede, 5 parts of lopseed, 12 parts of levisticum, 18 parts of ground beetle, wood
15 parts of soft-shelled turtle, 7 parts of Semen Lablab Album, 16 parts of dark plum, 9 parts of loguat leaf, 4 parts of Semen Cuscutae, 13 parts of witloof, 21 parts of the Fen, pig Xian of the fruit of Chinese magnoliavine 4,
13 parts of cactus, 7 parts of rhizoma imperatae, 5 parts of the wind-weed, 12 parts of dragon Lei.
3. a kind of preparation method of the medicine for the treatment of facial nerve paralysis as claimed in claim 1 or 2, comprises the following steps：
Wherein, nexine composition powder contains the extract of scorpio, stiff silkworm, centipede, ground beetle；
Outer layer composition contains the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf, Tu thread
Son, witloof, fruit of Chinese magnoliavine, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract.
4. preparation method according to claim 3, it is characterised in that
The scorpio, stiff silkworm, centipede, the extract of ground beetle are prepared by the following method and obtained：
It is coarse powder by scorpio, stiff silkworm, centipede, broken ground beetle insects medicinal powder；The 8-12 times of water measured is added into coarse powder, 58 are warming up to
DEG C, low-temperature dynamic is extracted or ultrasonic wave extraction 3 times, 6 hours every time, extraction fluid and the dregs of a decoction, and 8-12 times is added into the dregs of a decoction
The water of amount, is warming up to 80 DEG C, extracts 3 times, 2 hours every time, extraction fluid and the dregs of a decoction；Carrying obtained by merging in above-mentioned steps
Liquid is taken, by concentrating, being dried to obtain insects medicament extract.
5. preparation method according to claim 4, it is characterised in that
Take the Radix Astragali, Radix Codonopsis, vomiting nut, lopseed, levisticum, semen momordicae, Semen Lablab Album, dark plum, loguat leaf, Semen Cuscutae, witloof, the five tastes
Sub-, pig Xian, cactus, rhizoma imperatae, the wind-weed, dragon Lei extract co-grinding, are first extracted with 75% ethanol, and extract solution reclaims second
Alcohol, obtains extract A, and water will be added in fixed residue, is then extracted 3 times with ether shaking, 1 times of amount, merges ether and carry every time
Liquid is taken, solvent is recovered under reduced pressure and obtains extract B to dry, extract A and extract B are merged, 10 times of medicinal material amounts are added water to, stood
12 hours, filtering, filtrate is by processed good AB-8 large pore resin absorption columns, first with the water rinse resin post of 4 times of column volumes
To colourless, water lotion is discarded, then with 70% alcohol flushing resin post of 5 times of column volumes, be spray-dried, be made after eluent concentration
Extract.
6. the preparation method according to any one in claim 3 to 5, it is characterised in that by nexine combination and outer layer group
Compound, which is respectively placed in, is pressed into diameter 1.5-2cm, thickness 2.5-3.5cm ointment cake on forming machine；By ointment cake be placed in 5.5cm ×
On the air-permeable paper adhesive plaster of 5.5cm planes.
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|---|---|---|---|---|
| CN1733167A (en) * | 2005-08-26 | 2006-02-15 | 米绍武 | External applied Chinese traditional medicine plaster for curing facial paralysis and process for preparing the same |
| CN101657208A (en) * | 2007-03-05 | 2010-02-24 | 河北以岭医药研究院有限公司 | A kind of Chinese medicine composition, its contained insect medicine extract and preparation method thereof |
| CN102293953A (en) * | 2011-08-27 | 2011-12-28 | 张丽香 | Ovientvine, chrysanthemum and stiff silkworm decoction for treating idiopathic facial palsy |
| CN102641490A (en) * | 2012-04-16 | 2012-08-22 | 朱廷学 | Medicinal extract for treating facial nerve paralysis |
| CN103330857A (en) * | 2013-07-04 | 2013-10-02 | 高新华 | Pharmaceutical composition for treating peripheral facial paralysis |
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2017
- 2017-08-01 CN CN201710648781.9A patent/CN107308372A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1733167A (en) * | 2005-08-26 | 2006-02-15 | 米绍武 | External applied Chinese traditional medicine plaster for curing facial paralysis and process for preparing the same |
| CN101657208A (en) * | 2007-03-05 | 2010-02-24 | 河北以岭医药研究院有限公司 | A kind of Chinese medicine composition, its contained insect medicine extract and preparation method thereof |
| CN102293953A (en) * | 2011-08-27 | 2011-12-28 | 张丽香 | Ovientvine, chrysanthemum and stiff silkworm decoction for treating idiopathic facial palsy |
| CN102641490A (en) * | 2012-04-16 | 2012-08-22 | 朱廷学 | Medicinal extract for treating facial nerve paralysis |
| CN103330857A (en) * | 2013-07-04 | 2013-10-02 | 高新华 | Pharmaceutical composition for treating peripheral facial paralysis |
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