CN107296669A - 一种可降解气管外悬挂支架及其间接3d打印方法 - Google Patents
一种可降解气管外悬挂支架及其间接3d打印方法 Download PDFInfo
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- CN107296669A CN107296669A CN201710353755.3A CN201710353755A CN107296669A CN 107296669 A CN107296669 A CN 107296669A CN 201710353755 A CN201710353755 A CN 201710353755A CN 107296669 A CN107296669 A CN 107296669A
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- silica gel
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- degradable
- tracheae
- cylindrical ring
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- 239000000725 suspension Substances 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title claims abstract description 22
- 238000010146 3D printing Methods 0.000 title claims abstract description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 69
- 239000000741 silica gel Substances 0.000 claims abstract description 61
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 61
- 239000011347 resin Substances 0.000 claims abstract description 24
- 229920005989 resin Polymers 0.000 claims abstract description 24
- 210000003437 trachea Anatomy 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 14
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- 238000001816 cooling Methods 0.000 claims abstract description 5
- 239000004744 fabric Substances 0.000 claims abstract description 5
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- 238000001291 vacuum drying Methods 0.000 claims description 8
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 claims description 6
- 238000000016 photochemical curing Methods 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000004632 polycaprolactone Substances 0.000 claims description 4
- 239000000377 silicon dioxide Substances 0.000 claims description 4
- 238000007711 solidification Methods 0.000 claims description 4
- 230000008023 solidification Effects 0.000 claims description 4
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 3
- 239000003292 glue Substances 0.000 claims description 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 229910052710 silicon Inorganic materials 0.000 claims description 3
- 239000010703 silicon Substances 0.000 claims description 3
- 238000004506 ultrasonic cleaning Methods 0.000 claims description 2
- 241000894006 Bacteria Species 0.000 claims 1
- 238000001727 in vivo Methods 0.000 abstract description 2
- 230000003746 surface roughness Effects 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 4
- 238000007639 printing Methods 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010056397 Tracheomalacia Diseases 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 208000027205 Congenital disease Diseases 0.000 description 1
- 208000029767 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010051867 Tracheal injury Diseases 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 210000004704 glottis Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000007641 inkjet printing Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- -1 poly- Decanedioic acid glycerine ester Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/40—Plastics, e.g. foam or rubber
- B29C33/405—Elastomers, e.g. rubber
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/42—Casting under special conditions, e.g. vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y10/00—Processes of additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Mechanical Engineering (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
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CN201710353755.3A CN107296669B (zh) | 2017-05-18 | 2017-05-18 | 一种可降解气管外悬挂支架及其间接3d打印方法 |
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CN201710353755.3A CN107296669B (zh) | 2017-05-18 | 2017-05-18 | 一种可降解气管外悬挂支架及其间接3d打印方法 |
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CN107296669A true CN107296669A (zh) | 2017-10-27 |
CN107296669B CN107296669B (zh) | 2019-11-26 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108611269A (zh) * | 2018-05-02 | 2018-10-02 | 上海市肺科医院 | 一种腔内3d打印气管修补装置及气管修补方法 |
CN108746588A (zh) * | 2018-06-13 | 2018-11-06 | 东莞市原力无限打印科技有限公司 | 利用3d打印制作金属模具的制备方法及金属材料 |
CN109821064A (zh) * | 2019-02-18 | 2019-05-31 | 扬州大学 | 纳米二氧化硅修饰的3d打印气管支架及其制备方法 |
CN110640950A (zh) * | 2019-09-24 | 2020-01-03 | 中国人民解放军东部战区总医院 | 一种个体化肠瘘支架制作方法及其适用模具 |
WO2021099091A1 (de) * | 2019-11-22 | 2021-05-27 | Novatech Sa | Verfahren zur herstellung eines implantats aus einem biokompatiblen silikon |
Citations (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5258027A (en) * | 1991-01-24 | 1993-11-02 | Willy Rusch Ag | Trachreal prosthesis |
CN1654028A (zh) * | 2005-01-21 | 2005-08-17 | 清华大学 | 一种基于溶芯技术的组织工程复杂管网状支架成形方法 |
CN101108145A (zh) * | 2007-08-14 | 2008-01-23 | 西安交通大学 | 仿生人工半关节体及其制造工艺 |
US20080195189A1 (en) * | 2007-02-13 | 2008-08-14 | Cinvention Ag | Degradable reservoir implants |
CN101569572A (zh) * | 2008-04-30 | 2009-11-04 | 余少卿 | 钛合金外置型气管支架 |
FR2941862A1 (fr) * | 2009-02-12 | 2010-08-13 | Tokendo | Endoprothese tracheale ou tracheobronchique |
US20120035715A1 (en) * | 2010-08-09 | 2012-02-09 | Boston Scientific Scimed, Inc. | Tracheal Stent With Longitudinal Ribs to Minimize Stent Movement, Coughing and Halitosis |
CN102920538A (zh) * | 2012-11-06 | 2013-02-13 | 国家康复辅具研究中心 | 假肢接受腔制造方法及系统 |
CN103157149A (zh) * | 2011-12-14 | 2013-06-19 | 西安瑞捷生物科技有限公司 | 一种组织工程支架 |
US20130158651A1 (en) * | 2011-12-14 | 2013-06-20 | The Regents Of The University Of Michigan | Porous Bidirectional Bellowed Tracheal Reconstruction Device |
CN103976805A (zh) * | 2014-05-29 | 2014-08-13 | 西安交通大学 | 水凝胶/高分子聚合物薄膜肌肉组织支架的制造方法 |
CN105055060A (zh) * | 2015-08-04 | 2015-11-18 | 上海交通大学医学院附属上海儿童医学中心 | 一种气管支架及其应用 |
CN105473103A (zh) * | 2013-05-31 | 2016-04-06 | 新加坡国立大学 | 一种人工气管假体和/或发音假体材料及其制造方法 |
CN105496615A (zh) * | 2016-01-25 | 2016-04-20 | 张�杰 | 一种覆膜气道支架 |
CN105616043A (zh) * | 2016-03-18 | 2016-06-01 | 常州大学 | 一种基于3d打印及注模的硅酮个体化气道支架制备技术 |
CN105853022A (zh) * | 2016-06-01 | 2016-08-17 | 上海交通大学医学院附属上海儿童医学中心 | 气管支架及采用该气管支架的组织工程气管及其应用 |
CN106421904A (zh) * | 2016-09-19 | 2017-02-22 | 西安交通大学 | 一种凝胶注模3d打印及电解还原制备多孔植入物的方法 |
-
2017
- 2017-05-18 CN CN201710353755.3A patent/CN107296669B/zh active Active
Patent Citations (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5258027A (en) * | 1991-01-24 | 1993-11-02 | Willy Rusch Ag | Trachreal prosthesis |
CN1654028A (zh) * | 2005-01-21 | 2005-08-17 | 清华大学 | 一种基于溶芯技术的组织工程复杂管网状支架成形方法 |
US20080195189A1 (en) * | 2007-02-13 | 2008-08-14 | Cinvention Ag | Degradable reservoir implants |
CN101108145A (zh) * | 2007-08-14 | 2008-01-23 | 西安交通大学 | 仿生人工半关节体及其制造工艺 |
CN101569572A (zh) * | 2008-04-30 | 2009-11-04 | 余少卿 | 钛合金外置型气管支架 |
FR2941862A1 (fr) * | 2009-02-12 | 2010-08-13 | Tokendo | Endoprothese tracheale ou tracheobronchique |
US20120035715A1 (en) * | 2010-08-09 | 2012-02-09 | Boston Scientific Scimed, Inc. | Tracheal Stent With Longitudinal Ribs to Minimize Stent Movement, Coughing and Halitosis |
CN103157149A (zh) * | 2011-12-14 | 2013-06-19 | 西安瑞捷生物科技有限公司 | 一种组织工程支架 |
US20130158651A1 (en) * | 2011-12-14 | 2013-06-20 | The Regents Of The University Of Michigan | Porous Bidirectional Bellowed Tracheal Reconstruction Device |
CN102920538A (zh) * | 2012-11-06 | 2013-02-13 | 国家康复辅具研究中心 | 假肢接受腔制造方法及系统 |
CN105473103A (zh) * | 2013-05-31 | 2016-04-06 | 新加坡国立大学 | 一种人工气管假体和/或发音假体材料及其制造方法 |
CN103976805A (zh) * | 2014-05-29 | 2014-08-13 | 西安交通大学 | 水凝胶/高分子聚合物薄膜肌肉组织支架的制造方法 |
CN105055060A (zh) * | 2015-08-04 | 2015-11-18 | 上海交通大学医学院附属上海儿童医学中心 | 一种气管支架及其应用 |
CN105496615A (zh) * | 2016-01-25 | 2016-04-20 | 张�杰 | 一种覆膜气道支架 |
CN105616043A (zh) * | 2016-03-18 | 2016-06-01 | 常州大学 | 一种基于3d打印及注模的硅酮个体化气道支架制备技术 |
CN105853022A (zh) * | 2016-06-01 | 2016-08-17 | 上海交通大学医学院附属上海儿童医学中心 | 气管支架及采用该气管支架的组织工程气管及其应用 |
CN106421904A (zh) * | 2016-09-19 | 2017-02-22 | 西安交通大学 | 一种凝胶注模3d打印及电解还原制备多孔植入物的方法 |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108611269A (zh) * | 2018-05-02 | 2018-10-02 | 上海市肺科医院 | 一种腔内3d打印气管修补装置及气管修补方法 |
CN108611269B (zh) * | 2018-05-02 | 2022-05-27 | 上海市肺科医院 | 一种腔内3d打印气管修补装置及气管修补方法 |
CN108746588A (zh) * | 2018-06-13 | 2018-11-06 | 东莞市原力无限打印科技有限公司 | 利用3d打印制作金属模具的制备方法及金属材料 |
CN109821064A (zh) * | 2019-02-18 | 2019-05-31 | 扬州大学 | 纳米二氧化硅修饰的3d打印气管支架及其制备方法 |
CN110640950A (zh) * | 2019-09-24 | 2020-01-03 | 中国人民解放军东部战区总医院 | 一种个体化肠瘘支架制作方法及其适用模具 |
WO2021099091A1 (de) * | 2019-11-22 | 2021-05-27 | Novatech Sa | Verfahren zur herstellung eines implantats aus einem biokompatiblen silikon |
US11801618B2 (en) | 2019-11-22 | 2023-10-31 | Novatech Sa | Method for producing an implant from a biocompatible silicone |
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