CN107281273A - A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent - Google Patents
A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent Download PDFInfo
- Publication number
- CN107281273A CN107281273A CN201710608095.9A CN201710608095A CN107281273A CN 107281273 A CN107281273 A CN 107281273A CN 201710608095 A CN201710608095 A CN 201710608095A CN 107281273 A CN107281273 A CN 107281273A
- Authority
- CN
- China
- Prior art keywords
- carbon dioxide
- glossy privet
- fruit
- supercritical carbon
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Extraction Or Liquid Replacement (AREA)
- Fats And Perfumes (AREA)
- Preparation Of Fruits And Vegetables (AREA)
Abstract
The present invention relates to a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, including pretreatment, charging, temperature-rise period, boost process and analysis such as calculate at the process.The method for the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent that the present invention is provided includes, the fruit of glossy privet is crushed and is put into the extraction kettle of supercritical carbon dioxide extraction apparatus, the temperature and pressure of extraction kettle and separating still is set respectively, after extraction time is reached, extract is collected from separating still, that is fruit of glossy privet liposoluble constituent, and calculate its yield.The present invention uses supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, and without using organic solvent, in the absence of subsequent treatment, and extraction time is short, and extraction efficiency is high, unit interval high income, and preferably, process stabilizing is reproducible for color state.
Description
Technical field
The present invention relates to vegetable seeds abstraction technique field, more particularly to a kind of supercritical carbon dioxide extracting fruit of glossy privet fat
The method of soluble components.
Background technology
The fruit of glossy privet is Oleaceae plants glossy privet LigustrumlucidumAit. dry mature fruit, first recorded in the Eastern Han Dynasty
《Sheng Nong's herbal classic》Top grade is classified as, nourishing liver and kidney, improving eyesight black hair, for the deficiency of liver-yin and kidney-yin, dizziness ear toot, soreness and weakness of waist and knees, beard and hair is early
In vain, mesh is secretly failed to understand, Heat Diabetes, osteopyrexia and fever.Mainly contain terpene, it is flavonoids, benzyl carbinol glycoside, volatile oil, phosphatide, many
The chemical compositions such as sugar, aliphatic acid, amino acid, trace element, with liver protection, immunological regulation, antiatherosclerosis, it is hypoglycemic,
Reducing blood lipid, anti-inflammatory, anti-aging, it is antitumor to wait pharmacological action.
Oleanolic acid is main active component in the fruit of glossy privet, and toxicity is very low, with multiple biological activities, such as antiviral,
Anti-inflammatory, calm, enhancing is immune, control platelet aggregation, reducing blood lipid, hypoglycemic, the multiple pharmacological effect such as liver protection.The neat pier of non-prescribed medicine
Tartaric acid piece and oleanolic acid capsule etc. are widely used, and effect is notable.
Ursolic acid is main active component in the fruit of glossy privet, small toxicity, with calmness, anti-inflammatory, antibacterial, anti-diabetic, anti-
The various biological effects such as ulcer, reduction blood glucose, ursolic acid also has obvious anti-oxidation function and antitumor activity, thus quilt
It is widely used as medicine and cosmetic material.
Chinese patent application CN101775049A discloses a kind of method of the extraction purification rhodioside from the fruit of glossy privet, should
Technique is using the fruit of glossy privet as raw material, and 15-50% ethanol is stewed, and drying, gained crude product is scattered in its 5-8 times cold water for measuring (V/W),
Plus its 3-5 times ethyl acetate for measuring (V/W) is extracted, aqueous phase crosses molecular cut off 300-500 NF membrane removal of impurities, permeate decompression
The 1/10-1/15 of original volume is concentrated into, is stood still for crystals, then saturation dissolves in 90-95% methanol, recrystallizes 3 times and is produced
Product.
Chinese patent application CN101704857A discloses a kind of isolating and purifying for special component specnuezhenide of glossy privet fruit
Technique, to the fruit of glossy privet using ethanol heating extraction, be concentrated into dry cream, water dissolving, successively with petroleum ether, chloroform, extracting n-butyl alcohol,
And separate n-butanol portion by macroporous absorbent resin, silicagel column purifying produces Specnuezhenide.
At present, the research of the fruit of glossy privet is focused mostly on main medicinal part pharmacological research and chemical constituent analysis, in recent years
Result of study for degenerative diseases of aged shows that the fruit of glossy privet is the integration of drinking and medicinal herbs medicinal material of great DEVELOPMENT PROSPECT, fruit of glossy privet production
Amount is big, and cost is low, awaits further exploitation.
At present, the extracting method of fruit of glossy privet liposoluble constituent is mainly steam distillation, and fruit of glossy privet volatile oil is easily
Volatilization, time-consuming, low yield, and liposoluble constituent extracts incomplete.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of supercritical carbon dioxide extracting fruit of glossy privet fat
The method of soluble components.The method that the use supercritical carbon dioxide that the present invention is provided extracts fruit of glossy privet liposoluble constituent, is extracted
Time is short, and extraction efficiency is high, extracts relatively complete.
The technical scheme is that：
A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, comprises the following steps：
S1 is pre-processed：The fruit of glossy privet is put into vacuum drying chamber, 50 DEG C of dryings to constant weight, taken out, it is 50 to be crushed to particle diameter
Mesh, obtains fruit of glossy privet coarse powder；
S2 feeds：Fruit of glossy privet coarse powder 150-250g obtained by weighing step S1, is put into supercritical carbon dioxide extraction apparatus
In extraction kettle, the supercritical carbon dioxide extraction apparatus includes 1 extraction kettle, separation reactor I, separation reactor I I and separation reactor I II,
Seal extraction kettle；
S3 temperature-rise periods：Start refrigeration machine switch, set the temperature of extraction kettle as 35-55 DEG C, set the temperature of separating still
For 35-55 DEG C；
S4 boost process：4-6 DEG C is down in refrigerator temps, and the temperature of extraction kettle, separating still reaches the temperature of setting
And when stable, the gas cylinder and air-source inflow valve of carbon dioxide are opened, the air in extract and separate system is first discharged, works as extraction
When pressure is consistent with pressure of storage tank, starts high-pressure pump, extraction kettle pressure is risen to 15-40MPa, separating still pressure is risen to 6-
15MPa, starts the cycle over extraction, and carbon dioxide flow is 25-35kg/h, and sets extraction time to be 30-240min；
S5 analyses are calculated：After extraction time is reached, fruit of glossy privet liposoluble constituent is collected from separating still.
Further, the step S2 weighs fruit of glossy privet coarse powder 200g obtained by step S1.
Further, the temperature that the step S3 sets separation reactor I sets separation reactor I I temperature as 45 as 35-55 DEG C
DEG C, separation reactor I II temperature is set as 45 DEG C.
Further, the temperature that the step S3 sets separation reactor I sets separation reactor I I temperature as 45 as 55 DEG C
DEG C, separation reactor I II temperature is set as 45 DEG C.
Further, the step S4 is down to 5 DEG C in refrigerator temps.
Further, the step S4 makes extraction kettle pressure rise to 18MPa.
Further, the step S4 adjusts the regulating valve of separating still, and it is 8-15MPa, separation reactor I I to make separation reactor I pressure
Pressure is 6-10MPa, and separation reactor I II pressure is 6-8MPa.
Further, the step S4 adjusts the regulating valve of separating still, and it is 8MPa, separation reactor I I to make separation reactor I pressure
Pressure is 6MPa, and separation reactor I II pressure is 6MPa.
Further, the step S4 carbon dioxide flows are 28kg/h, and set extraction time to be 120min.
Compared with prior art, the method tool for the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent that the present invention is provided
There is following advantage：
(1) present invention extracts fruit of glossy privet liposoluble constituent using supercritical carbon dioxide, better than traditional steam distillation,
Without using organic solvent, in the absence of subsequent treatment.
(2) extraction time that the present invention extracts fruit of glossy privet liposoluble constituent using supercritical carbon dioxide is short, extraction efficiency
Height, is extracted relatively complete.
(3) using the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent that provides of the present invention, obtain it is fat-soluble into
Divide color state preferable.
Embodiment
To more fully understand the present invention, further specific elaboration, but not is made to the present invention below by following examples
Limitation of the invention is can be regarded as, some made for those skilled in the art according to foregoing invention content are nonessential
Improve with adjusting, be also considered as being within the scope of the present invention.
Supercritical carbon dioxide extraction apparatus used of the invention, by Zhongshan University's Chinese medicine Integrated manufacture and process control technology
The wise and farsighted overcritical technology ＆ development Co.'s joint manufacture in research center and Nantong, model 231-50-06.
Embodiment 1, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, comprises the following steps：
S1 is pre-processed：The fruit of glossy privet is put into vacuum drying chamber, 50 DEG C of dryings to constant weight, taken out, it is 50 to be crushed to particle diameter
Mesh, obtains fruit of glossy privet coarse powder；
S2 feeds：Fruit of glossy privet coarse powder 150g obtained by weighing step S1, is put into the extraction of supercritical carbon dioxide extraction apparatus
In kettle, the supercritical carbon dioxide extraction apparatus includes 1 extraction kettle, separation reactor I, separation reactor I I and separation reactor I II, sealing
Extraction kettle；
S3 temperature-rise periods：Start refrigeration machine switch, set the temperature of extraction kettle as 55 DEG C, set the temperature of separating still, if
The temperature for determining separation reactor I is 55 DEG C, sets separation reactor I I temperature as 45 DEG C, sets separation reactor I II temperature as 45 DEG C；
S4 boost process：4 DEG C are down in refrigerator temps, and the temperature of extraction kettle, separating still reaches the temperature of setting simultaneously
And when stable, the gas cylinder and air-source inflow valve of carbon dioxide are opened, the air in extract and separate system is first discharged, when extraction pressure
When power is consistent with pressure of storage tank, starts high-pressure pump, extraction kettle pressure is risen to 40MPa, it is 15MPa, separation to make separation reactor I pressure
Kettle II pressure is 8MPa, and separation reactor I II pressure is 6MPa, starts the cycle over extraction, carbon dioxide flow is 25kg/h, and sets extraction
It is 240min to take the time；
S5 analyses are calculated：After extraction time is reached, fruit of glossy privet liposoluble constituent is collected from separating still.
Embodiment 2, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, comprises the following steps：
S1 is pre-processed：The fruit of glossy privet is put into vacuum drying chamber, 50 DEG C of dryings to constant weight, taken out, it is 50 to be crushed to particle diameter
Mesh, obtains fruit of glossy privet coarse powder；
S2 feeds：Fruit of glossy privet coarse powder 250g obtained by weighing step S1, is put into the extraction of supercritical carbon dioxide extraction apparatus
In kettle, the supercritical carbon dioxide extraction apparatus includes 1 extraction kettle, separation reactor I, separation reactor I I and separation reactor I II, sealing
Extraction kettle；
S3 temperature-rise periods：Start refrigeration machine switch, set the temperature of extraction kettle as 35 DEG C, set the temperature of separating still, if
The temperature for determining separation reactor I is 45 DEG C, sets separation reactor I I temperature as 45 DEG C, sets separation reactor I II temperature as 45 DEG C；
S4 boost process：6 DEG C are down in refrigerator temps, and the temperature of extraction kettle, separating still reaches the temperature of setting simultaneously
And when stable, the gas cylinder and air-source inflow valve of carbon dioxide are opened, the air in extract and separate system is first discharged, when extraction pressure
When power is consistent with pressure of storage tank, starts high-pressure pump, extraction kettle pressure is risen to 20MPa, it is 8MPa, separation to make separation reactor I pressure
Kettle II pressure is 8MPa, and separation reactor I II pressure is 6MPa, starts the cycle over extraction, carbon dioxide flow is 35kg/h, and sets extraction
It is 180min to take the time；
S5 analyses are calculated：After extraction time is reached, fruit of glossy privet liposoluble constituent is collected from separating still.
Embodiment 3, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, comprises the following steps：
S1 is pre-processed：The fruit of glossy privet is put into vacuum drying chamber, 50 DEG C of dryings to constant weight, taken out, it is 50 to be crushed to particle diameter
Mesh, obtains fruit of glossy privet coarse powder；
S2 feeds：Fruit of glossy privet coarse powder 200g obtained by weighing step S1, is put into the extraction of supercritical carbon dioxide extraction apparatus
In kettle, the supercritical carbon dioxide extraction apparatus includes 1 extraction kettle, separation reactor I, separation reactor I I and separation reactor I II, sealing
Extraction kettle；
S3 temperature-rise periods：Start refrigeration machine switch, set the temperature of extraction kettle as 50 DEG C, set the temperature of separating still, if
The temperature for determining separation reactor I is 55 DEG C, sets separation reactor I I temperature as 45 DEG C, sets separation reactor I II temperature as 45 DEG C；
S4 boost process：5 DEG C are down in refrigerator temps, and the temperature of extraction kettle, separating still reaches the temperature of setting simultaneously
And when stable, the gas cylinder and air-source inflow valve of carbon dioxide are opened, the air in extract and separate system is first discharged, when extraction pressure
When power is consistent with pressure of storage tank, starts high-pressure pump, extraction kettle pressure is risen to 18MPa, it is 8MPa, separation to make separation reactor I pressure
Kettle II pressure is 6MPa, and separation reactor I II pressure is 6MP, starts the cycle over extraction, carbon dioxide flow is 28kg/h, and sets extraction
It is 120min to take the time；
S5 analyses are calculated：After extraction time is reached, fruit of glossy privet liposoluble constituent is collected from separating still.
Embodiment 3 is highly preferred embodiment of the present invention, and the result of the test by three parallel tests is as shown in table 1.
Table 1：Three parallel test results
Make discovery from observation, separation reactor I discharging is yellow green sticky oil product, separation reactor I I dischargings are yellow, viscous
Product, color state is preferable.As can be seen from Table 1, the supercritical carbon dioxide that provides of the present invention extract the fruit of glossy privet it is fat-soluble into
The extraction efficiency divided is high, process stabilizing.
Embodiment 4, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With, the step S3 and set extraction kettle temperature as 30 DEG C, set the temperature of separation reactor I as 35 DEG C；The step S4
Extraction kettle pressure is set to rise to 12MPa, it is 6MPa to make separation reactor I pressure.
Embodiment 5, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With, the step S3 and set extraction kettle temperature as 30 DEG C, set the temperature of separation reactor I as 45.
Embodiment 6, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With the step S3 simultaneously sets the temperature of extraction kettle as 30 DEG C；The step S4 makes extraction kettle pressure rise to 40MPa, makes
Separation reactor I pressure is 20MPa.
Embodiment 7, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With, the step S3 and set extraction kettle temperature as 40 DEG C, set the temperature of separation reactor I as 45 DEG C；The step S4
Extraction kettle pressure is set to rise to 12MPa, it is 20MPa to make separation reactor I pressure.
Embodiment 8, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With the step S3 simultaneously sets the temperature of extraction kettle as 40 DEG C；The step S4 makes separation reactor I pressure be 6MPa.
Embodiment 9, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With, the step S3 and set extraction kettle temperature as 40 DEG C, set the temperature of separation reactor I as 35 DEG C；The step S4
Extraction kettle pressure is set to rise to 40MPa.
Embodiment 10, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With the step S4 makes extraction kettle pressure rise to 12MPa, and it is 8MPa to make separation reactor I pressure.
Embodiment 11, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With the step S3 sets the temperature of separation reactor I as 35 DEG C；The step S4 makes separation reactor I pressure be 20MPa.
Embodiment 12, a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent
The method of the supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent is similar to Example 3, with embodiment 3 not
With the step S3 sets the temperature of separation reactor I as 45 DEG C；The step S4 makes extraction kettle pressure rise to 40MPa, makes point
It is 6MPa from kettle I pressure.
Test example one, using comprehensive grading weighting method to supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent of the present invention
Method evaluated
1st, test specimen：Fruit of glossy privet liposoluble constituent obtained by embodiment 4-12.
2nd, test method：
The method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent of the present invention is entered using comprehensive grading weighting method
Row is evaluated.With fruit of glossy privet liposoluble constituent yield and outward appearance (shade, clarity) for evaluation index.Each evaluation index weighting
Processing is as follows：The extraction products collection efficiency (extract content/medicinal material inventory)/9 of supercritical carbon dioxide extracting product scoring=respectively
Product maximum output, index components content scoring=index components content (extract content × oleanolic acid and bear are extracted in sample
Tartaric acid content) the highest content of index components (oleanolic acid and ursolic acid) in/9 samples.Comprehensive grading=overcritical dioxy
Change carbon extraction product scoring × 50%+ index components contents scoring × 50%.
3rd, result of the test：
Result of the test is as shown in table 2 and table 3.
Table 2：The extraction product assay and index components content of test specimen
Table 3：Appraisal result
It can be drawn by table 2, the average yield of fruit of glossy privet extract is 7.13, index components (oleanolic acid and ursolic acid)
Average content is 1.08%.Experiment is found, using the method for supercritical carbon dioxide of the present invention extraction fruit of glossy privet liposoluble constituent
When, it is yellow, viscous product that separation reactor I discharging, which is yellow green sticky oil product, separation reactor I I discharges, and color state is preferable.
It can be drawn, the present invention extracts fruit of glossy privet liposoluble constituent using supercritical carbon dioxide, extracted by table 2 and table 3
Efficiency high, extracts relatively complete, and liposoluble constituent color state is preferable.
Claims (8)
1. a kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent, it is characterised in that comprise the following steps：
S1 is pre-processed：The fruit of glossy privet is put into vacuum drying chamber, 50 DEG C of dryings to constant weight, taken out, be crushed to particle diameter for 50 mesh, obtain
Fruit of glossy privet coarse powder；
S2 feeds：Fruit of glossy privet coarse powder 150-250g obtained by weighing step S1, is put into the extraction of supercritical carbon dioxide extraction apparatus
In kettle, the supercritical carbon dioxide extraction apparatus includes 1 extraction kettle, separation reactor I, separation reactor I I and separation reactor I II, sealing
Extraction kettle tightens extraction kettle cover, and checks separation kettle cover and have whether closing valve is closed；
S3 temperature-rise periods：Start refrigeration machine switch, set the temperature of extraction kettle as 35-55 DEG C, set the temperature of separating still as 35-
55℃；
S4 boost process：Be down to 4-6 DEG C in refrigerator temps, and extraction kettle, separating still temperature reach setting temperature and
When stable, the gas cylinder and air-source inflow valve of carbon dioxide are opened, the air in extract and separate system is first discharged, works as extracting pressure
When consistent with pressure of storage tank, start high-pressure pump, extraction kettle pressure is risen to 15-40MPa, separating still pressure is risen to 6-15MPa,
The regulating valve of separating still is adjusted, extraction is started the cycle over, carbon dioxide flow is 25-35kg/h, and sets extraction time to be 30-
240min；
S5 analyses are calculated：After extraction time is reached, fruit of glossy privet liposoluble constituent is collected from separating still.
2. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 1, it is characterised in that
The step S2 weighs fruit of glossy privet coarse powder 200g obtained by step S1.
3. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 1, it is characterised in that
The step S3 sets the temperature of separation reactor I as 35-55 DEG C, sets separation reactor I I temperature as 45 DEG C, setting separation reactor I II's
Temperature is 45 DEG C.
4. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 3, it is characterised in that
The step S3 sets the temperature of separation reactor I as 55 DEG C, sets separation reactor I I temperature as 45 DEG C, setting separation reactor I II temperature
Spend for 45 DEG C.
5. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 1, it is characterised in that
The step S4 makes extraction kettle pressure rise to 18MPa.
6. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 1, it is characterised in that
The step S4 adjusts the regulating valve of separating still, and it is 8-15MPa to make separation reactor I pressure, and separation reactor I I pressure is 6-10MPa, point
It is 6-8MPa from kettle III pressure.
7. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 6, it is characterised in that
The step S4 adjusts the regulating valve of separating still, and it is 8MPa to make separation reactor I pressure, and separation reactor I I pressure is 6MPa, separation reactor I II
Pressure is 6MPa.
8. the method for supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent according to claim 1, it is characterised in that
The step S4 carbon dioxide flows are 28kg/h, and set extraction time to be 120min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710608095.9A CN107281273A (en) | 2017-07-24 | 2017-07-24 | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710608095.9A CN107281273A (en) | 2017-07-24 | 2017-07-24 | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107281273A true CN107281273A (en) | 2017-10-24 |
Family
ID=60102147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710608095.9A Pending CN107281273A (en) | 2017-07-24 | 2017-07-24 | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107281273A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107858197A (en) * | 2017-11-01 | 2018-03-30 | 广东金妮宝科技发展有限公司 | A kind of production and processing method of low acid value high-quality edible oil tea-seed oil |
| WO2022214908A1 (en) * | 2021-04-06 | 2022-10-13 | Lubrizol Advanced Materials, Inc. | Ligustrum lucidum extract useful for the treatment and/or care of the skin |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101411400A (en) * | 2008-12-04 | 2009-04-22 | 东北农业大学 | Glossy privet fruit extract for improving production performance and immunity function of laying hen and use method |
| CN104083900A (en) * | 2014-07-15 | 2014-10-08 | 广州中大南沙科技创新产业园有限公司 | Method for extracting volatile components from Pandanus amaryllifolius Roxb leaves |
| CN106336946A (en) * | 2016-10-31 | 2017-01-18 | 中山大学 | Supercritical carbon dioxide sealwort seed oil extraction method |
-
2017
- 2017-07-24 CN CN201710608095.9A patent/CN107281273A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101411400A (en) * | 2008-12-04 | 2009-04-22 | 东北农业大学 | Glossy privet fruit extract for improving production performance and immunity function of laying hen and use method |
| CN104083900A (en) * | 2014-07-15 | 2014-10-08 | 广州中大南沙科技创新产业园有限公司 | Method for extracting volatile components from Pandanus amaryllifolius Roxb leaves |
| CN106336946A (en) * | 2016-10-31 | 2017-01-18 | 中山大学 | Supercritical carbon dioxide sealwort seed oil extraction method |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107858197A (en) * | 2017-11-01 | 2018-03-30 | 广东金妮宝科技发展有限公司 | A kind of production and processing method of low acid value high-quality edible oil tea-seed oil |
| WO2022214908A1 (en) * | 2021-04-06 | 2022-10-13 | Lubrizol Advanced Materials, Inc. | Ligustrum lucidum extract useful for the treatment and/or care of the skin |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103451022B (en) | Method for integrally extracting volatile oil, polysaccharide and flavone from elsholtzia haichowensis sun | |
| CN103980242B (en) | The method of Moringa flavones is extracted from leaf of Moringa | |
| CN105294628B (en) | A kind of method that separation from chrysanthemum indicum prepares flavones ingredient | |
| CN101019909B (en) | Supercritical safflower extracting process | |
| CN107281273A (en) | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet liposoluble constituent | |
| CN106398861A (en) | Entrainer-containing supercritical CO2 extraction method of ganderma lucidum spore oil | |
| CN103705647B (en) | A kind of CO2the process of supercritical methanol technology extracting gold jasmine tea leaf flavonoids | |
| CN101926452B (en) | Wild jujube leaf total flavonoids extract and preparation method thereof | |
| CN102911783A (en) | Method for extracting angelica oil from angelica | |
| CN109810789A (en) | A kind of extracting method of ginkgo essential oil | |
| CN106699819B (en) | The preparation method of Penta-O-galloyl-D-glucopyranose chemical reference substance | |
| CN101703539A (en) | Method for extracting okra by using supercritical carbon dioxide | |
| CN103755583A (en) | Method for extracting and separating ceramide in konjac flying powder | |
| CN103301255A (en) | Supercritical extraction device of radix ampelopsis extract and extraction method thereof | |
| WO2016110216A1 (en) | Method for extracting stilbene compounds | |
| CN105454528A (en) | Face-beautifying skin-moisturizing healthy tea and production method thereof | |
| CN104721240A (en) | Process for extracting and separating moringa oleifera flavones and saponin from moringa oleifera leaves | |
| CN107325150A (en) | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet ursolic acid | |
| CN106036992B (en) | The method for extracting cigarette additive from faenum graecum with supercritical extraction | |
| CN104522822A (en) | Mixed extraction process for effective components of red dates and kudzuvine roots | |
| CN101481398B (en) | Method for preparing high-purity 5-hydroxy-lamiophlomiol A glycoside and lamiophlomiol A glycoside extract from lamiophlomiol at the same time | |
| CN107384584A (en) | A kind of method of supercritical carbon dioxide extracting fruit of glossy privet lubricant component | |
| CN104086615A (en) | Method for preparing mogroside V from siraitia grosvenori | |
| CN108283638B (en) | The application of rhizoma polygonati compound and preparation method, fat reducing diet food and drug | |
| CN107082791A (en) | A kind of method that phenylethanoid glycosides are extracted from saline cistanche |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171024 |
|
| RJ01 | Rejection of invention patent application after publication |