CN107260878A - It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof - Google Patents

It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof Download PDF

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Publication number
CN107260878A
CN107260878A CN201710577037.4A CN201710577037A CN107260878A CN 107260878 A CN107260878 A CN 107260878A CN 201710577037 A CN201710577037 A CN 201710577037A CN 107260878 A CN107260878 A CN 107260878A
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medicine
acute appendicitis
chinese
dried
rehmannia
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Sichuan Yichuang Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of decoction medicine for treating acute appendicitis provided according to the traditional Chinese medical science the understanding mechanism of acute appendicitis, each component and its mass parts ratio of the medicine is as follows:15~28g of honeysuckle, 15~45g of dandelion, 12~32g of prepared rhizome of rehmannia, 5~23g of rheum officinale, 25~45g of Chinese lobelia, 8~16g of moutan bark, 2~10g of licorice, 3~12g of dried orange peel, 15~36g of Semen Benincasae, the dried immature fruit of citron orange(Fry)5~12g;The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine for treating acute appendicitis, particularly supply The field of the decoction medicine that Acute Appendicitis Patients are used and preparation method thereof.
Background technology
Doctor thinks:Acute appendicitis is surgical common disease, occupies the first place of various acute abdomen.Metastatic right lower abdominal pain and door screen Tail point tenderness, Blumberg's sign are its common clinical manifestation, but the change of illness state multiterminal of acute appendicitis.Its clinical manifestation is lasting Right lower abdominal pain, the Nausea and vomiting aggravated with paroxysmal, most patient's leucocytes and neutrophil count increase.Right Lower Abdomen Appendix area(McBurney point)Tenderness, then be the sick vital sign.Acute appendicitis typically point four types:Acute simplex appendix Inflammation, acute suppurative appendicitis, gangrene and perforating appendicitis and periappendiceal abscess.
So, with regard to how to find it is a kind of can effectively treat the medicine of acute appendicitis, be we at present be badly in need of to be solved Problem.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment acute appendicitis, people gradually appreciate the traditional Chinese medical science Treat the advantage of acute appendicitis, and the advantage such as good effect, instant effect, toxic side effect be small over the course for the treatment of, for existing west The present situation for treating acute appendicitis is cured, the purpose of the present invention is to be to provide a kind of decoction medicine for treating acute appendicitis, with Solve the problem of Acute Appendicitis Patients are got well early.The medicine is using common Chinese medicine as raw material, by selection rationally Medicine and mass parts ratio, can effectively treat above-mentioned acute appendicitis.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:One kind is provided and treats acute appendicitis Decoction medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
15~28g of honeysuckle, 15~45g of dandelion, 12~32g of prepared rhizome of rehmannia, 5~23g of rheum officinale, 25~45g of Chinese lobelia, moutan bark 8~16g, 2~10g of licorice, 3~12g of dried orange peel, 15~36g of Semen Benincasae, the dried immature fruit of citron orange(Fry)5~12g.
It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof, it is characterised in that each group of the medicine Divide and its mass parts are than as follows:
18~25g of honeysuckle, 18~40g of dandelion, 15~28g of prepared rhizome of rehmannia, 8~20g of rheum officinale, 28~40g of Chinese lobelia, moutan bark 10~14g, 3~9g of licorice, 6~11g of dried orange peel, 18~31g of Semen Benincasae, the dried immature fruit of citron orange(Fry)8~11g.
It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof, it is characterised in that " preferred plan " Each component and its mass parts of medicine are than as follows:
Honeysuckle 22g, dandelion 35g, prepared rhizome of rehmannia 25g, rheum officinale 17g, Chinese lobelia 35g, moutan bark 12g, licorice 8g, dried orange peel 10g, Semen Benincasae 26g, the dried immature fruit of citron orange(Fry)10g.
It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof, it is characterised in that methods described includes as follows Step is prepared from:
A, in addition to lower after rheum officinale, above-mentioned raw materials Chinese medicine is picked after impurity and dust, coarse grain is respectively crushed into according to mass parts ratio Shape is decocted a drug wrapped;
B, the raw material Chinese medicine wrapped is put into cold boiling water and soaks half an hour, then again by soaked medicine and immersion medicine The clarified solution of thing is put into marmite in the lump, and the cold boiling water for injecting medicine 37mm decoct 48 minutes for the first time, after leaching decoction, The tepor boiling water for re-injecting medicine 35mm carries out second of decoction 35 minutes, and secondary mixing is condensed into 50% milli of Chinese medicine liquid 510 Rise standby.
It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof, it is characterised in that the instructions of taking is:Will The Chinese medicine liquid prepared was taken with one day, one portion per day, and once a dose in the morning, afternoon and evening, milliliter/time of dosage 170.Medication 3~8 days, Disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Honeysuckle, nature and flavor:It is sweet, cold, with it is clearing heat and detoxicating the effect of, for treat warm disease heating, toxic-heat and blood stasis, carbuncle swells furunculosis, Larynx numbness and multi-infection disease;
Dandelion, nature and flavor:Bitter;It is sweet, cold in nature, the effect of with clearing heat and detoxicating, carbuncle that disappears dissipating bind, for treating acute mastitis, lung carbuncle, intestines Carbuncle, mumps, malignant boil carbuncle toxin, red eye, swell pain, cold, fever, cough, abscess of throat, stomach fire, enteritis, dysentery, hepatitis, courage frighten it is scorching, Urinary tract infections, snake bite and insect sting;
Prepared rhizome of rehmannia, nature and flavor:Sweet, tepor, the effect of with nourishing yin and supplementing blood, beneficial to spirit and marrow, for treating the deficiency of liver-yin and kidney-yin, waist and knee acid Soft, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizziness, tinnitus, Poliosis;
Rheum officinale, nature and flavor:It is bitter, cold, the effect of with real heat, broken stagnant, row hemostasis is rushed down, stagnated for treating real heat constipation, dyspepsia, Burn and scald, change are controlled in stomachache, acute appendicitis, acute infectious hepatitis, blood stasis, toothache, bleeding from five sense organs or subcutaneous tissue, acute conjunctivitis, external application Purulence skin disease, carbuncle swells sore;
Chinese lobelia, nature and flavor:It is sweet, mild-natured, the effect of with clearing heat and detoxicating, inducing diuresis for removing edema, for treating venomous snake bite, carbuncle swells malignant boil Sore, tonsillitis, warm rash, tinea pedis, traumatic injury, jaundice with damp-heat pathogen, appendicitis, enteritis, ephritis, cirrhotic ascites and a variety of cancers Disease;
Moutan bark, nature and flavor:It is arduous, cool, the effect of with heat-clearing, cool blood and blood, dispersing blood stasis, for treat heat invading xuefen, hair spot, Frightened epilepsy, tell, be defeated in battle, having blood in stool, hectic fever due to yin labor heat, Amenorrhea, abdominal mass, large carbuncle, flutter damage etc. disease;
Licorice, nature and flavor:It is sweet, flat, with invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription the effect of, For treating weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, abirritant It is thing toxicity, strong;
Dried orange peel, nature and flavor:It is pungent, bitter, warm-natured, with qi-regulating and in, it is eliminating dampness and eliminating phlegm, the effect of sharp water defaecation, for treating taste Discord, abdominal distention, do not feel like eating, vomiting hiccup, phlegm-damp obstructing lung, coughing with a lot of sputum, chest diaphragm full vexed, vertigo, oedema, urine The diseases such as unfavorable, constipation, acute mastitis mange, middle ichthyophagy crab poison, wine poison;
Semen Benincasae, nature and flavor:Sweet, cold nature, the effect of with clearing lung and eliminating phlegm, the carbuncle that disappears apocenosis, dampness removing, is coughed for treating phlegm heat Cough, lung carbuncle, acute appendicitis, gonorrhoea, band under, tinea pedis, oedema, stranguria;
The dried immature fruit of citron orange(Fry)Nature and flavor:It is bitter, cold, with relieving stagnant Qi, dissipate ruffian, rush down phlegm, disperse accumulations the effect of, for treating fullness and oppression of chest and abdomen, the obstruction of qi in the chest, ruffian Bitterly, phlegm addiction, oedema, dyspepsia, constipation, gastroptosis, metroptosis, prolapse of the anus.
Medicine of the present invention is the principle based on Chinese traditional treatment acute appendicitis, is thought from pharmacological action and its mechanism of action: With regard to acute appendicitis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned acute appendicitis, is prepared using the formula Medicine effect it is good, instant effect is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail:
Embodiment 1:
A kind of decoction medicine for treating acute appendicitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower:
Honeysuckle 22g, dandelion 35g, prepared rhizome of rehmannia 25g, rheum officinale 17g, Chinese lobelia 35g, moutan bark 12g, licorice 8g, dried orange peel 10g, Semen Benincasae 26g, the dried immature fruit of citron orange(Fry)10g.
Embodiment 2:
A kind of decoction medicine for treating acute appendicitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower:
Honeysuckle 25g, dandelion 40g, prepared rhizome of rehmannia 28g, rheum officinale 20g, Chinese lobelia 40g, moutan bark 14g, licorice 9g, dried orange peel 11g, Semen Benincasae 31g, the dried immature fruit of citron orange(Fry)11g.
Embodiment 3:
A kind of decoction medicine for treating acute appendicitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower:
Honeysuckle 28g, dandelion 45g, prepared rhizome of rehmannia 32g, rheum officinale 23g, Chinese lobelia 45g, moutan bark 16g, licorice 10g, dried orange peel 12g, Semen Benincasae 36g, the dried immature fruit of citron orange(Fry)12g.
Model case
Through clinical conditions Acute Appendicitis Patients totally 798, the age is 408 of more than 26 years old, and only 390 are 26 years old Below.775 fully recovered in 788 patients, effective 23, total effective rate is up to 100%.

Claims (3)

1. a kind of decoction medicine for treating acute appendicitis, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
15~28g of honeysuckle, 15~45g of dandelion, 12~32g of prepared rhizome of rehmannia, 5~23g of rheum officinale, 25~45g of Chinese lobelia, moutan bark 8~16g, 2~10g of licorice, 3~12g of dried orange peel, 15~36g of Semen Benincasae, the dried immature fruit of citron orange(Fry)5~12g.
2. the decoction medicine for the treatment of acute appendicitis according to claim 1, it is characterised in that each group of the medicine Divide and its mass parts are than as follows:
18~25g of honeysuckle, 18~40g of dandelion, 15~28g of prepared rhizome of rehmannia, 8~20g of rheum officinale, 28~40g of Chinese lobelia, moutan bark 10~14g, 3~9g of licorice, 6~11g of dried orange peel, 18~31g of Semen Benincasae, the dried immature fruit of citron orange(Fry)8~11g.
3. the decoction medicine of the treatment acute appendicitis according to claim 1 to 2, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows:
Honeysuckle 22g, dandelion 35g, prepared rhizome of rehmannia 25g, rheum officinale 17g, Chinese lobelia 35g, moutan bark 12g, licorice 8g, dried orange peel 10g, Semen Benincasae 26g, the dried immature fruit of citron orange(Fry)10g.
CN201710577037.4A 2017-07-14 2017-07-14 It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof Withdrawn CN107260878A (en)

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CN201710577037.4A CN107260878A (en) 2017-07-14 2017-07-14 It is a kind of to treat decoction medicine of acute appendicitis and preparation method thereof

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Application publication date: 20171020