CN107260788A - A kind of medical disinfectant and preparation method thereof - Google Patents
A kind of medical disinfectant and preparation method thereof Download PDFInfo
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- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/43—Guanidines
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- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A61Q19/10—Washing or bathing preparations
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Abstract
The invention discloses a kind of medical disinfectant and preparation method thereof, the medical disinfectant includes according to the raw material of parts by weight:15 40 parts of two ammonium of the double ethylenes of 40 85 parts of alcohol, bromination, 1 15 parts of lauryl diethanolamide, 3 20 parts of chlorohexidene, 0.5 12 parts of Dodecyl Polyglucosides, 3 20 parts of Blumea oil, 1 12 parts of babassu oil amido propyl amine oxide, 0.02 3 parts of chlorhexidine acetate, 0.05 5 parts of coco-betaine, 0.1 6 parts of tocopherol, 0.5 10 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 30 70 parts of deionized water.Chlorhexidine acetate is dissolved in alcohol, the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene, Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, 1-hydroxy ethylidene-1,1-diphosphonic acid is sequentially added;Deionized water is stirring evenly and then adding into, stirs and produces.The present invention not only has excellent sterilization ability, and also with good cleaning action, safety and environmental protection has no toxic side effect to human body.
Description
Technical field
The present invention relates to disinfectant technical field, specifically a kind of medical disinfectant and preparation method thereof.
Background technology
Disinfectant refers to be used to kill pathogenic microorganism on communication media, reaches the preparation of innoxious requirement, it is not
Antibiotic is same as, its main function in diseases prevention is to eliminate pathogenic microorganism outside human body, cuts off the propagation of infectious disease
Approach, reaches the purpose of control infectious disease.Also often disinfectant is called " chemosterilant " to people.The water that disinfectant is acted on according to it
It is flat to be divided into bactericidal agent, high effect disinfectants, middle effect disinfectants, low effect disinfectants.Bactericidal agent, which can kill all microorganisms, reaches it
Required to sterilizing, including formaldehyde, glutaraldehyde, oxirane, Peracetic acid, hydrogen peroxide, chlorine dioxide, chlorine, copper sulphate, life
Lime, ethanol, etc..High effect disinfectants can kill all bacterial propagules(Including mycobacteria), virus, fungi and its spore
Deng also having certain killing effect to bacterial spore, reach in high level disinfection requirement, including chlorine-containing disinfectant, ozone, methyl second
Ureide derivative compound, double-chain quaternary ammonium salt etc..Middle effect disinfectants can only kill mycobacteria, fungi, virus and bacterial propagule etc.
Microorganism, reaches that sterilization is required, including iodine-containing disinfectant, alcohol disinfectant, disinfectant phenolic etc..Low effect disinfectants can only be killed
Bacterial propagule and close nma virus, reach disinfectant requirement, quaternary ammonium disinfectant, the Chlorhexidine such as including benzalkonium bromide(Washing must
It is safe)Deng biguanides disinfectant.
But the reasonability of existing medical disinfecting agent prescription is still to be improved, and excitant is larger, although it has good
Good sterilizability, but its spatter property is poor.
The content of the invention
It is an object of the invention to provide a kind of medical disinfectant and preparation method thereof, to solve to carry in above-mentioned background technology
The problem of going out.
To achieve the above object, the present invention provides following technical scheme:
A kind of medical disinfectant, includes according to the raw material of parts by weight:15-40 parts of two ammonium of the double ethylenes of 40-85 parts of alcohol, bromination, ten
1-15 parts of dialkyl group diglycollic amide, 3-20 parts of chlorohexidene, 0.5-12 parts of Dodecyl Polyglucosides, 3-20 parts of Blumea oil, Ba Ba
1-12 parts of oleamide of reviving propyl group amine oxide, 0.02-3 parts of chlorhexidine acetate, 0.05-5 parts of coco-betaine, tocopherol 0.1-
6 parts, 0.5-10 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 30-70 parts of deionized water.
It is used as further scheme of the invention:The medical disinfectant, includes according to the raw material of parts by weight:Alcohol 45-80
Part, 18-35 parts of two ammonium of the double ethylenes of bromination, 2-12 parts of lauryl diethanolamide, 5-18 parts of chlorohexidene, Dodecyl Polyglucosides
0.8-10 parts, 5-18 parts of Blumea oil, 2-10 parts of babassu oil amido propyl amine oxide, 0.04-2.5 parts of chlorhexidine acetate, coconut palm
0.08-4 parts of oleic acid glycine betaine, 0.1-5 parts of tocopherol, 0.8-8 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 35-65 parts of deionized water.
It is used as further scheme of the invention:The medical disinfectant, includes according to the raw material of parts by weight:Alcohol 50-75
Part, 20-32 parts of two ammonium of the double ethylenes of bromination, 2-10 parts of lauryl diethanolamide, 6-15 parts of chlorohexidene, Dodecyl Polyglucosides
1-8 parts, 8-15 parts of Blumea oil, 2-8 parts of babassu oil amido propyl amine oxide, 0.05-2 parts of chlorhexidine acetate, cocounut oil it is sour-sweet
0.1-3 parts of dish alkali, 0.2-4 parts of tocopherol, 1-6 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 40-60 parts of deionized water.
A kind of preparation method of medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into, stirs and produces medical disinfectant.
It is used as further scheme of the invention:The speed of stirring is 100-300r/min for the first time.
It is used as further scheme of the invention:The speed of second of stirring is 200-500r/min.
It is used as further scheme of the invention:The time of second of stirring is 0.8-2h.
Compared with prior art, the beneficial effects of the invention are as follows:
Medical disinfectant of the present invention not only has excellent sterilization ability, also with good cleaning action.The present invention is medical to disappear
Toxic agent formula is reasonable, and safety and environmental protection has no toxic side effect to human body.Preparation method of the present invention is simple and easy to apply, suitable for a wide range of popularization
Using.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 40 parts of alcohol, bromination
15 parts of ammonium, 1 part of lauryl diethanolamide, 3 parts of chlorohexidene, 0.5 part of Dodecyl Polyglucosides, 3 parts of Blumea oil, babassu oil
1 part of amido propyl amine oxide, 0.02 part of chlorhexidine acetate, 0.05 part of coco-betaine, 0.1 part of tocopherol, hydroxy ethylidene
0.5 part of di 2 ethylhexyl phosphonic acid, 30 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 100r/min speed, produced with 200r/min speed stirring 0.8h medical
Disinfectant.
Embodiment 2
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 85 parts of alcohol, bromination
40 parts of ammonium, 15 parts of lauryl diethanolamide, 20 parts of chlorohexidene, 12 parts of Dodecyl Polyglucosides, 20 parts of Blumea oil, Babassu
12 parts of oleamide propyl group amine oxide, 3 parts of chlorhexidine acetate, 5 parts of coco-betaine, 6 parts of tocopherol, 1-hydroxy ethylidene-1,1-diphosphonic acid
10 parts, 70 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 300r/min speed, medical disappear is produced with 500r/min speed stirring 2h
Toxic agent.
Embodiment 3
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 45 parts of alcohol, bromination
18 parts of ammonium, 2 parts of lauryl diethanolamide, 5 parts of chlorohexidene, 0.8 part of Dodecyl Polyglucosides, 5 parts of Blumea oil, babassu oil
2 parts of amido propyl amine oxide, 0.04 part of chlorhexidine acetate, 0.08 part of coco-betaine, 0.1 part of tocopherol, hydroxy ethylidene
0.8 part of di 2 ethylhexyl phosphonic acid, 35 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 150r/min speed, medical disappear is produced with 250r/min speed stirring 1h
Toxic agent.
Embodiment 4
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 80 parts of alcohol, bromination
35 parts of ammonium, 12 parts of lauryl diethanolamide, 18 parts of chlorohexidene, 10 parts of Dodecyl Polyglucosides, 18 parts of Blumea oil, Babassu
10 parts of oleamide propyl group amine oxide, 2.5 parts of chlorhexidine acetate, 4 parts of coco-betaine, 5 parts of tocopherol, 1-hydroxy ethylene-1,1-diphosphonic
Sour 8 parts, 65 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 250r/min speed, produced with 450r/min speed stirring 1.8h medical
Disinfectant.
Embodiment 5
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 50 parts of alcohol, bromination
20 parts of ammonium, 2 parts of lauryl diethanolamide, 6 parts of chlorohexidene, 1 part of Dodecyl Polyglucosides, 8 parts of Blumea oil, Babassu oleoyl
2 parts of amine propyl group amine oxide, 0.05 part of chlorhexidine acetate, 0.1 part of coco-betaine, 0.2 part of tocopherol, 1-hydroxy ethylene-1,1-diphosphonic
Sour 1 part, 40 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 200r/min speed, medical disappear is produced with 300r/min speed stirring 1h
Toxic agent.
Embodiment 6
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 75 parts of alcohol, bromination
32 parts of ammonium, 10 parts of lauryl diethanolamide, 15 parts of chlorohexidene, 8 parts of Dodecyl Polyglucosides, 15 parts of Blumea oil, Babassu
8 parts of oleamide propyl group amine oxide, 2 parts of chlorhexidine acetate, 3 parts of coco-betaine, 4 parts of tocopherol, 1-hydroxy ethylidene-1,1-diphosphonic acid 6
Part, 60 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 220r/min speed, produced with 400r/min speed stirring 1.2h medical
Disinfectant.
Embodiment 7
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 60 parts of alcohol, bromination
25 parts of ammonium, 4 parts of lauryl diethanolamide, 10 parts of chlorohexidene, 3 parts of Dodecyl Polyglucosides, 10 parts of Blumea oil, babassu oil
4 parts of amido propyl amine oxide, 0.5 part of chlorhexidine acetate, 0.5 part of coco-betaine, 1 part of tocopherol, 1-hydroxy ethylene-1,1-diphosphonic
Sour 2 parts, 50 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 250r/min speed, produced with 350r/min speed stirring 1.5h medical
Disinfectant.
Embodiment 8
In the embodiment of the present invention, a kind of medical disinfectant includes according to the raw material of parts by weight:The double ethylenes two of 70 parts of alcohol, bromination
30 parts of ammonium, 8 parts of lauryl diethanolamide, 12 parts of chlorohexidene, 6 parts of Dodecyl Polyglucosides, 12 parts of Blumea oil, babassu oil
6 parts of amido propyl amine oxide, 1 part of chlorhexidine acetate, 2 parts of coco-betaine, 2 parts of tocopherol, 1-hydroxy ethylidene-1,1-diphosphonic acid 4
Part, 55 parts of deionized water.
The preparation method of the medical disinfectant, comprises the following steps:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into 200r/min speed, produced with 380r/min speed stirring 1.6h medical
Disinfectant.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity, those skilled in the art should
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It may be appreciated other embodiment.
Claims (7)
1. a kind of medical disinfectant, it is characterised in that include according to the raw material of parts by weight:The double ethylenes two of 40-85 parts of alcohol, bromination
15-40 parts of ammonium, 1-15 parts of lauryl diethanolamide, 3-20 parts of chlorohexidene, 0.5-12 parts of Dodecyl Polyglucosides, Blumea oil
3-20 parts, 1-12 parts of babassu oil amido propyl amine oxide, 0.02-3 parts of chlorhexidine acetate, coco-betaine 0.05-5
Part, 0.1-6 parts of tocopherol, 0.5-10 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 30-70 parts of deionized water.
2. medical disinfectant according to claim 1, it is characterised in that include according to the raw material of parts by weight:Alcohol 45-80
Part, 18-35 parts of two ammonium of the double ethylenes of bromination, 2-12 parts of lauryl diethanolamide, 5-18 parts of chlorohexidene, Dodecyl Polyglucosides
0.8-10 parts, 5-18 parts of Blumea oil, 2-10 parts of babassu oil amido propyl amine oxide, 0.04-2.5 parts of chlorhexidine acetate, coconut palm
0.08-4 parts of oleic acid glycine betaine, 0.1-5 parts of tocopherol, 0.8-8 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 35-65 parts of deionized water.
3. medical disinfectant according to claim 1, it is characterised in that include according to the raw material of parts by weight:Alcohol 50-75
Part, 20-32 parts of two ammonium of the double ethylenes of bromination, 2-10 parts of lauryl diethanolamide, 6-15 parts of chlorohexidene, Dodecyl Polyglucosides
1-8 parts, 8-15 parts of Blumea oil, 2-8 parts of babassu oil amido propyl amine oxide, 0.05-2 parts of chlorhexidine acetate, cocounut oil it is sour-sweet
0.1-3 parts of dish alkali, 0.2-4 parts of tocopherol, 1-6 parts of 1-hydroxy ethylidene-1,1-diphosphonic acid, 40-60 parts of deionized water.
4. the preparation method of a kind of medical disinfectant as described in claim 1-3 is any, it is characterised in that including following step
Suddenly:
Chlorhexidine acetate is dissolved in alcohol, sequentially add the double ammoniums of ethylene two of bromination, lauryl diethanolamide, chlorohexidene,
Dodecyl Polyglucosides, Blumea oil, babassu oil amido propyl amine oxide, coco-betaine, tocopherol, hydroxy ethylidene two
Phosphonic acids;Deionized water is stirring evenly and then adding into, stirs and produces medical disinfectant.
5. the preparation method of medical disinfectant according to claim 4, it is characterised in that the speed of stirring is for the first time
100-300r/min。
6. the preparation method of medical disinfectant according to claim 4, it is characterised in that the speed of stirring is for the second time
200-500r/min。
7. the preparation method of medical disinfectant according to claim 4, it is characterised in that the time of stirring is for the second time
0.8-2h。
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CN111306980A (en) * | 2020-03-16 | 2020-06-19 | 中冷智元环境技术有限公司 | Bacteriostatic cooling tower with accelerated cooling |
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CN105456548A (en) * | 2015-12-11 | 2016-04-06 | 郭健 | Foam disinfectant for medical use and preparation process of foam disinfectant |
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CN104472569A (en) * | 2014-11-27 | 2015-04-01 | 苏州市贝克生物科技有限公司 | Medical sanitizer and preparation method thereof |
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CN105456548A (en) * | 2015-12-11 | 2016-04-06 | 郭健 | Foam disinfectant for medical use and preparation process of foam disinfectant |
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CN111306980A (en) * | 2020-03-16 | 2020-06-19 | 中冷智元环境技术有限公司 | Bacteriostatic cooling tower with accelerated cooling |
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