CN107258800A - A kind of composition pesticide containing avermectin B2a - Google Patents
A kind of composition pesticide containing avermectin B2a Download PDFInfo
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- CN107258800A CN107258800A CN201710383866.9A CN201710383866A CN107258800A CN 107258800 A CN107258800 A CN 107258800A CN 201710383866 A CN201710383866 A CN 201710383866A CN 107258800 A CN107258800 A CN 107258800A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
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Abstract
The present invention relates to a kind of composition pesticide containing avermectin B2a, said composition includes two kinds of components of A and B of effective dose, and component A is avermectin B2a, the one kind of B component in Diacloden, Nitenpyram or clothianidin；The quality parts ratio of component A and B component is 20:1~1:50；The gross mass of active ingredient accounts for the 1% ~ 80% of the whole quality of the pharmaceutical preparations in preparation, and remaining is the auxiliary element that allows to use and receive in agricultural chemicals.The formulation of composition pesticide of the present invention is missible oil, suspending agent, water dispersible granules, microemulsion, soluble liquid, granule, it is adaptable to prevent and kill off the parasitic nematode of preventing and treating harm root system of plant and for preventing and kill off the suckings pest such as aphid, trialeurodes vaporariorum.The composition pesticide of the present invention has notable synergistic effect, expands and applies target, can delay the resistance development of nicotinoids medicament, extends its service life.
Description
Technical field
The present invention relates to a kind of composition pesticide, and in particular to a kind of composition pesticide containing avermectin B2a, belongs to agriculture
Medicine application field.
Background technology
Service life, the resistance of alleviating target organismses, expansion of the research of composition pesticide for extension new varieties of pesticides
Have great importance in terms of preventing and treating spectrum, reduction cost accounting, raising drug effect and environmental safety.Therefore, countries in the world pair
The research of pestsides synthesis is all extremely paid attention to.
AVM is the ten hexa-atomic Macrocyclic lactone compounds that a class has desinsection, mite killing, eelworm-killing activity.As comparing
Ripe biological pesticide product, in past decades, AVM mainly studies B1A, but research shows both at home and abroad at present,
B2a also has larger application value.Current Some Domestic producer has obtained the purification preparation method of avermectin B2a.Result of study
Show, avermectin B2a has preferable prevention effect to various pests such as root-knot nematodes.
Clothianidin（clothianidin）It is a class highly effective and safe, the novel pesticide of high selectivity, it is acted on and nicotine
Acetylcholine receptor type seemingly, with tagging, stomach toxicity and systemic activity.It is mainly used in preventing on paddy rice, vegetables, fruit tree and other crops
Eliminate aphis, leafhopper, thrips, the Semiptera such as plant hopper, coleoptera, the insecticide of Diptera and some Lepidoptera class pests.Its structure
Novel, special, performance is more excellent compared with traditional nicotinic insecticide.
Diacloden（Thiamethoxam）It is a kind of second generation nicotinoids high-efficient low toxicity insecticide of brand new, to insect
With stomach toxicity, tag and systemic activity, for foliar spray and soil root irrigation.Inhaled rapidly, and conduct by interior after its dispenser
To each position of plant, there is good preventive effect to sucking pest such as aphid, plant hopper, leafhopper, aleyrodid etc..
Nitenpyram（nitenpyram）, Nitenpyram is a kind of efficient, wide spectrum, novel nicotinamide insecticide, and it is acted on
Mechanism has nerve block effect to mainly act on insect nerve to the axle synaptic receptor of insect.With remarkable interior suction and
Osmosis, consumption is few, and toxicity is low, and the lasting period is long, the advantages of to crop safety without poisoning, is widely used in gardening and agriculturally
Homoptera and Hemipteran pest are prevented and treated, the lasting period was up to 14 days or so.
Apply single chemical insecticide long-term continuous high dose, easily cause residual, environmental pollution of medicament etc. one
Series of problems.At present, the potential resistance problem of anabasine is increasingly protruded.The present inventor had shown that by a series of research, Ah
Tie up rhzomorph B2a and selected from clothianidin, Nitenpyram, Diacloden any Pesticidal combination being combined into therein to aphid, white
Aleyrodid etc. pierces Xi Shi mouthpart insects and endangers the extremely strong synergistic effect of parasitic nematode of root system of plant, is mainly manifested in delaying drug resistance
Produce, improve prevention effect, reduction amount of application, reduce cost accounting, then complete the present invention.
The content of the invention
Prevention effect can be improved it is an object of the invention to provide one kind, slows down the compounding containing avermectin B2a of resistance
Synergistic pesticide mixtures.The present invention is adopted the following technical scheme that：
A kind of composition pesticide containing avermectin B2a, it includes component A and B component, and the A components are avermectin B2as,
The B components are one kind in Diacloden, Nitenpyram or clothianidin；The mass ratio of the A components and B components is 20:1~
1:50。
Further, it also includes auxiliary agent C；The component A and B component account for the 1% ~ 80% of composition gross mass.
Specifically, the formulation of the composition pesticide is missible oil；The auxiliary agent C includes emulsifying agent, cosolvent and solvent,
The mass percent of each component is：Component A 0.1 ~ 20%, B component 0.1 ~ 20%, emulsifying agent 5 ~ 15%, cosolvent 1 ~ 10%, solvent is mended
Foot 100%.Specifically production stage is：By active ingredient（Component A and B component）, solvent, cosolvent, emulsifying agent mixing, stirring is
Obtain the missible oil of respective quality percentage composition.
Specifically, the formulation of the composition pesticide is microemulsion；The auxiliary agent C includes emulsifying agent, solvent and water, respectively
The mass percent of component is：Component A 0.1 ~ 30%, B component 0.1 ~ 30%, emulsifying agent 5 ~ 20%, solvent 5% ~ 40%, water is supplied
To 100%.Specifically production stage is：By active ingredient（Component A and B component）, solvent, emulsifying agent etc. it is well mixed, it is to be dissolved
Add water stirring after even.The microemulsion of respective quality percentage composition is made.
Specifically, the formulation of the composition pesticide is aqueous suspension agent；The auxiliary agent C includes wetting agent, dispersant, prevented
Freeze agent, thickener, defoamer, pH values conditioning agent and water, the mass percent of each component is：Component A 0.1 ~ 50%, B component 0.1
~ 50%, wetting agent 0 ~ 2%, dispersant 4 ~ 20%, antifreezing agent 1 ~ 5%, thickener 0.01 ~ 2%, defoamer 0.1 ~ 0.8%, the regulation of pH values
Agent 0.1 ~ 5%, water supplies 100%.Specifically production stage is：First auxiliary agent is mixed, it is well mixed through high speed shear, add effectively into
Point（Component A and B component）, abrading-ball 2 ~ 3 hours in ball crusher make a diameter in below 5mm, you can aqueous suspension agent is made
Preparation.
Specifically, the formulation of the composition pesticide is soluble liquid；The auxiliary agent C includes cosolvent, emulsifying agent
And solvent, the mass percent of each component is：Component A 0.1 ~ 10%, B component 0.1 ~ 30%, cosolvent 1 ~ 20%, emulsifying agent 1 ~
20%, solvent complements to 100%.Specifically production stage is：By active ingredient（Component A and B component）, solvent, cosolvent, emulsifying agent
Mixing, stirring produces the soluble liquid of respective quality percentage composition.
Specifically, the formulation of the composition pesticide is granule；The auxiliary agent C includes wetting agent, dispersant, bonding
Agent and carrier, the mass percent of each component is：Component A 0.1 ~ 50%, B component 0.1 ~ 50%, wetting agent 0.1 ~ 10%, dispersant
0.1 ~ 15%, binding agent 0.1 ~ 14%, carrier complements to 100%.Specifically production stage is：By active ingredient（Component A and B component）、
Auxiliary agent, carrier etc. are well mixed, and are crushed with micro jet, through mediating, and are then added and are entered in fluidized-bed granulation dryer
Row granulation, dry, screening, are made the granule of respective quality percentage composition.
Specifically, the formulation of the composition pesticide is water dispersible granules；The auxiliary agent C include dispersant, wetting agent,
Disintegrant, binding agent and carrier, the mass percent of each component is：Component A 1 ~ 80%, B component 1 ~ 80%, dispersant 0.1 ~ 15%,
Wetting agent 0.1 ~ 10%, disintegrant 0.1 ~ 30%, binding agent 0.1 ~ 15%, carrier complements to 100%.Specifically production stage is：To have
Imitate composition（Component A and B component）, auxiliary agent, carrier etc. it is well mixed, crushed, through mediating, then added with micro jet
Granulated, dried, sieved in fluidized-bed granulation dryer, the water dispersible granules of respective quality percentage composition are made.
Further, described emulsifying agent is selected from calcium dodecyl benzene sulfonate and gathered with aliphatic acid polyethenoxy ether, alkyl phenol
Oxygen ethene ether sulfosuccinates, styrylphenol polyoxyethylene ether, NPE, castor oil polyoxyethylene
At least one of ether, aliphatic acid polyethenoxy base ester, polyoxyethylene aliphatic alcohol ether.
Further, the solvent is dimethylbenzene or biodiesel, toluene, diesel oil, methanol, ethanol, n-butanol, isopropyl
At least one of alcohol, turpentine oil, solvent naphtha, dimethylformamide, dimethyl sulfoxide (DMSO), water equal solvent.
Further, described dispersant is selected from polycarboxylate, lignosulfonates, the contracting of APES formaldehyde
Compound sulfate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, APES, fatty amine polyoxy second
At least one of alkene ether, polyoxyethylene carboxylate, glycerine fatty acid ester APEO.
Further, described wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, pull open powder resin acid
Copper X., wetting and penetrating agent F, alkylnaphthalene sulfonate, polyoxyethylene tri-styryl phosphenylic acid salt, spaonin powder, silkworm excrement, spaonin powder
At least one of.
Further, described disintegrant is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, carbonic acid
At least one of hydrogen sodium.
Further, described thickener be selected from xanthans, hydroxymethyl cellulose, hydroxyethyl cellulose, methylcellulose,
At least one of Magnesiumaluminumsilicate, polyvinyl alcohol.
Further, described antifreezing agent is selected from least one of ethylene glycol, propane diols, glycerine.
Further, described defoamer is selected from silicone oil, silicone compound, the saturated fat acids chemical combination of C10-20
At least one of aliphatic alcohols compound of thing, C8-10.
Further, described filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon, starch, lightweight
At least one of calcium carbonate.
A kind of purposes of composition pesticide described above, for preventing and kill off sucking pest and endangering posting for root system of plant
Raw nematode.The sucking pest includes aphid, trialeurodes vaporariorum etc..
A kind of method for preventing and kill off insect pest using above-mentioned composition pesticide, the composition is dressed seed, sprayed, shed or filled
Root is applied to crop.
The beneficial effects of the present invention are：
（1）The formulation product of the present invention belongs to the compatible agricultural chemicals of high-efficiency low-toxicity, low-residual, environment, meets environmental protection and production
The requirement of Agricultural product without pollution；
（2）The thorn Xi Shi mouthpart insects such as nematode and aphid, the trialeurodes vaporariorum of the formulation product of the present invention to endangering root system of plant have
Preferable prevention effect, synergy is obvious；
（3）Because the mechanism of action of composition active component is different, according to pest resistance insecticide theory and practice, the application of composition
The resistance development of avermectin B2a and nicotinoids agricultural chemicals can be delayed, extend its service life.
Brief description of the drawings
Fig. 1 is the structural formula of avermectin B2a.
Embodiment
In order to deepen the understanding of the present invention, the present invention is described in detail with reference to embodiment is echoed, the reality
It is exemplary to apply example, is only used for explaining the present invention, and protection domain is not constituted and limited.
Example of formulations
The avermectin B2a Nitenpyram missible oil of embodiment 1 12%
By avermectin B2a and Nitenpyram mass percent 1:1 prepares.Take avermectin B2a active compound 6%, Nitenpyram active compound
6%, emulsifying agent castor oil polyoxyethylene ether 10%, emulsifying agent calcium dodecyl benzene sulfonate 2%, cosolvent 1-METHYLPYRROLIDONE
10%, S-150 solvent naphtha are mended to 100%, and stirring and dissolving obtains 12% avermectin B2a Nitenpyram missible oil.Through examining Avermectin
Plain B2a contents 6.1%, Nitenpyram content 6.2%, outward appearance homogeneous phase transparent, emulsion stability is good after being mixed with water, and cold and hot storage is stable
Property is qualified.
Nitenpyram can also be substituted for clothianidin or Diacloden, new embodiment is formed.
The avermectin B2a clothianidin microemulsion of embodiment 2 12%
By avermectin B2a and clothianidin mass percent 1:2 prepare.Take the % of avermectin B2a active compound 4.0, clothianidin active compound
8%, solvent cyclohexanone 10%, cosolvent 1-METHYLPYRROLIDONE 10% adds emulsifying agent phenethyl phenol polyethenoxy ether 20%, mixing
Stir, add water and supply 100%, stirring obtains 12% avermectin B2a clothianidin microemulsion of homogeneous transparent.Through examine Ah
Rhzomorph B2a contents 4.1% are tieed up, clothianidin content 8.1%, cloud point is less than 60oC, outward appearance homogeneous phase transparent, property miscible with water is good, cold
Heat storage stability is qualified.
Clothianidin can also be substituted for Nitenpyram or Diacloden, new embodiment is formed.
The avermectin B2a Diacloden soluble liquid of embodiment 3 25%
By avermectin B2a and Diacloden mass percent 1:4 prepare.25% avermectin B2a Diacloden soluble liquid.Take
Avermectin B2a active compound 5%, Diacloden active compound 20%, emulsifying agent AEO 15%, cosolvent N- crassitudes
Ketone 10%, solubilizer dimethyl carbonate to 100%.After being uniformly mixed, essence puts 10h, filtering, and 25% avermectin B2a is made
Clothianidin soluble liquid.Through examine avermectin B2a content 5.2%, Diacloden content 20.1%, moisture 1.4%, outward appearance is homogeneous
Transparent, property miscible with water is good, cold and hot storage qualified stability.
Diacloden can also be substituted for Nitenpyram or clothianidin, new embodiment is formed.
The avermectin B2a Nitenpyram suspending agent of embodiment 4 35%
By avermectin B2a and Nitenpyram mass percent 1:6 prepare.Take avermectin B2a active compound 5%, clothianidin active compound
30%, wetting agent Nekal BX 1%, dispersant naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, antifreeze glycol 5%, thickener silicic acid
Magnalium 1%, defoamer organosilicon 0.2%, deionized water is mended to 100%.Through examining avermectin B2a content 5.1%, clothianidin content
30.2%, good dispersion after being mixed with water, suspensibility 99%, cold and hot storage qualified stability.
Nitenpyram can also be substituted for clothianidin or Diacloden, new embodiment is formed.
The avermectin B2a clothianidin granule of embodiment 5 11%
By avermectin B2a and clothianidin mass percent 1:10 prepare.Weigh avermectin B2a active compound 1%, clothianidin active compound
10%, dispersant sodium lignin sulfonate 10%, binding agent polyvinyl alcohol 5%, carrier attapulgite is mended to 100%.Above-mentioned raw materials are mixed
Close in cylinder and be well mixed, by extruding, granulation, dry, and 11% avermectin B2a clothianidin particle is made in screened step
Agent.Through examining avermectin B2a content 1.05%, clothianidin content 10.1%, moisture 1.4%, screening（Pass through 75 μm）98%, it is cold and hot
Store qualified stability.
Clothianidin can also be substituted for Nitenpyram or Diacloden, new embodiment is formed.
The avermectin B2a Diacloden water dispersible granules of embodiment 6 48%
By avermectin B2a and clothianidin mass percent 1:15 prepare.Weigh avermectin B2a active compound 3%, Diacloden active compound
45%, the mixture 4% of wetting agent alkylnaphthalene sulfonate and anion wetting agent, dispersant polycarboxylate 6%, disintegrant urea
25%, binding agent polyethylene glycol 2%, diatomite supplies 100%.It is mixed by conventional method, after stirring, through air-flow crushing
Machine is crushed and obtains female powder, then granulates, dries, sieving obtains 70% avermectin B2a clothianidin water dispersible granules.Through examine Ah
Tie up rhzomorph B2a contents 3.1%, Diacloden content 45.2%, moisture 2.2%, screening（Pass through 75 μm）98%, suspensibility 92% persistently rises
Bubble property（1min）10mL, wetability≤1min, heat storage stability is qualified.
Diacloden can also be substituted in Nitenpyram or clothianidin, form new embodiment.
Biological activity determination
In order to further appreciate that avermectin B2a combines the virulence to crop pests with clothianidin, substantial amounts of component has been carried out
Ratio screening experiment.
According to the abundant methods of Sun Yun, the synergy of pharmacy mix, i.e. CTC≤80 are evaluated according to co-toxicity coefficient (CTC) is
Joint action of antagonism, 80 ＜ CTC ＜ 120 are joint action of antagonism, and CTC >=120 are synergistic function.Survey toxicity index
(ATI)=(EC50 of the EC50/ reagent agents of standard agent) × 100；The virulence of theoretical toxicity index TTI=A medicaments refers to
In number × mixture in toxicity index × mixture of the percentage composition+B medicaments of A medicaments B medicaments percentage composition；Co-toxicity coefficient (
CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100.
Joint toxicity measuring in the aphid room of embodiment 7
Aphid Toxicity Determination is carried out using infusion process, and experiment target is designated as Cucumber blight.Fresh cabbage leaves are won, cutting ring is used
It is cut into soak in diameter 3cm former piece, the decoction being positioned ready for and takes out and dry at room temperature after 10s, is laid on and is lined with wetting
In the 3cm culture dishes of filter paper, 1 is put per ware.The chemicals treatment of 7 concentration of Setup Experiments, each processing is repeated 3 times, and is often repeated
Examination aphid 30 ~ 35；It is another to be laid on clear water immersion blade and after drying in culture dish as control.Culture dish lid is covered, will
Culture dish is put into 27 DEG C of temperature, relative humidity 70%, illumination 16:In 8 illumination box, aphid survival number is observed after 48 h
Amount, calculates the death rate and corrected mortality.Calculated by virulence regression equation v=a+bx, and carry out Chi-square Test.With machine value
Analytic approach obtain reagent agent it is lethal in dense LC50And its 95% confidence limit.As a result it is as shown in table 1.
The Toxicity Determination result of the aphid of table 1
The result of the co-toxicity of table 1 test shows that avermectin B2a and Thiamethoxam compound are in 20: 1~1: 50 ratio range
140 are all higher than to the co-toxicity coefficient CTC of Cucumber blight joint toxicity measuring, with notable synergistic effect.Especially 2: 1~1:
In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring in the cucumber root tie lines zooecium of embodiment 8
Root-knot nematode toxicity test uses decoction infusion method, and experiment target is designated as cucumber root-knot nematode.First use acetone solution active compound, root
Appropriate active component is made into several different ratios according to the result of preliminary experiment, then is diluted to each processing respectively with acetone
Several concentration gradients are stand-by.100ul is injected into each hole of 96 orifice plates, then adds equivalent root-knot nematode suspension, 25
With nematode survival number and death toll in each hole of microscopic counting after dark place is placed one week at DEG C.Calculate the death rate and correction is dead
Rate.Calculated by virulence regression equation v=a+bx, and carry out Chi-square Test.With machine value analytic approach obtain reagent agent it is lethal in
Dense LC50 and its 95% confidence limit.As a result it is as shown in table 2.
The Toxicity Determination result of the nematode of table 2
The result of the co-toxicity of table 2 test shows that avermectin B2a and clothianidin are interior to Huang in 20: 1~1: 50 ratio range
The co-toxicity coefficient CTC of melon root-knot nematode joint toxicity measuring is all higher than 120, with notable synergistic effect.Especially 1: 1~1:
In 15 ratio range, CTC is all higher than 200, and synergistic effect is notable.
Joint toxicity measuring in the trialeurodes vaporariorum room of embodiment 9
Trialeurodes vaporariorum Toxicity Determination is carried out using infusion process.Fresh cabbage leaves are won, diameter 3cm original is cut into cutting ring
Soaked in piece, the decoction being positioned ready for and take out and dry at room temperature after 10s, be laid on the 3cm culture dishes for being lined with wetting filter paper
In, put 1 per ware.The chemicals treatment of 7 concentration of Setup Experiments, each processing is repeated 3 times, and is often repeated for examination trialeurodes vaporariorum 30 ~ 35
Head；It is another to be laid on clear water immersion blade and after drying in culture dish as control.Culture dish lid is covered, culture dish is put into temperature
27 DEG C, relative humidity 70%, illumination 16:In 8 illumination box, trialeurodes vaporariorum amount of survival is observed after 48 h, death is calculated
Rate and corrected mortality.Calculated by virulence regression equation v=a+bx, and carry out Chi-square Test.Obtained with machine value analytic approach for examination
Medicament it is lethal in dense LC50And its 95% confidence limit.As a result it is as shown in table 3.
The Toxicity Determination result of the trialeurodes vaporariorum of table 3
The co-toxicity of table 3 test result show, avermectin B2a and Nitenpyram compounding 20: 1~1: 50 ratio range
The interior co-toxicity coefficient CTC to trialeurodes vaporariorum joint toxicity measuring is all higher than 120, with notable synergistic effect.Especially 5: 1~1:
In 15 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Field control effectiveness test
For the practical application effect of the more preferably composition pesticide of the checking present invention, embodiments of the invention preparation is prevented respectively
Control the test of pesticide effectiveness of root-knot nematode, aphid.
According to Gowing methods to avermectin B2a and clothianidin（Or Nitenpyram, Diacloden）Synergy commented
Valency, its formula is as follows：
Eo=X+Y-XY/100
In formula：Theoretical preventive effects of the Eo for insecticide A, B after mixed in formula, percentage preventive effect when X is insecticide A alone, Y is desinsection
Percentage preventive effect when agent B is alone, Eo is avermectin B2a and clothianidin（Or Nitenpyram, Diacloden）Mixed with certain ratio
Afterwards to the theoretical value or desired value of the prevention effect of target test worm；E is avermectin B2a and clothianidin（Or Nitenpyram, thiophene
Worm piperazine）To the actual value or observation of the prevention effect of target test worm after being mixed with certain ratio；Evaluation criterion：Work as E-Eo>10%
When, it is expressed as synergistic function；As -10%≤E-Eo≤10%, performance collaboration summation action；Work as E-Eo<When -10%, represent
For joint action of antagonism.
The root-knot nematode field efficacy of embodiment 9
Each embodiment preparation is diluted with water pouring ground by certain consumption（Granule directly spreads fertilizer over the fields）, 60d after chemicals treatment, take with
The method of machine sampling, per 5 points of samplings of cell, root-knot nematode hazard level is recorded in every 2 plants of random searching, investigation.Investigation side
Method is carried out by pesticide field efficacy medicine test criterion.Eelworm harm classification, which is used, pulls out a plant percentage：
0 grade：Without visible root nodule or pieces of an egg；1 grade：Root nodule total length account for always with length 1% -24%；2 grades：Root nodule total length
Account for 25% -49% always with length；3 grades：Root nodule total length account for always with length 50% -74%；4 grades：Root nodule total length is accounted for always
With 75%-the 100% of length.
Disease index=Σ（Diseases at different levels are with number × relative value of series）/（Investigate total strain number × 4）×100 ；
Prevention effect（%）=[1-（Handle disease index/control disease index）]×100.
The complex preparation of table 4 is to root-knot nematode field efficacy
Remarks：A is avermectin B2a, and B is Nitenpyram, clothianidin or Diacloden.
From table 4 as can be seen that avermectin B2a and Nitenpyram, clothianidin or Diacloden are in varing proportions after mixture,
Preventive effect to cucumber root-knot nematode and root-knot nematode is significantly improved, E-EOMore than 10%, substantially, preventing and treating is imitated for synergistic effect
It is really good, can effectively control harm of the root-knot nematode to host, raising to crop quality and increase production significant, have compared with
Strong popularizing value.
The aphid field efficacy of embodiment 10
Respectively using cucumber and wheat as crop, avermectin B2a and clothianidin, Nitenpyram, Pyraphione compound preparation pair are investigated
The field control effect of aphid, application method is blade face even spraying.Per experimental plot using 5 points of samplings, every is investigated 2 plants,
In 7 days statistics effect of chemical control after medicine, result of the test is shown in Table 5.
The field efficacy result of the aphid of table 5
Remarks：A is avermectin B2a, and B is Nitenpyram, clothianidin or Diacloden.
It is right from table 5 as can be seen that avermectin B2a and clothianidin, Nitenpyram, Diacloden are in varing proportions after mixture
The preventive effect of aphid is significantly improved, E-EOIt is all higher than 10%, substantially, prevention effect is good for synergistic effect, has and stronger promote the use of valency
Value.
The trialeurodes vaporariorum field efficacy of embodiment 11
Respectively using tomato and wild cabbage as crop, complex preparation is investigated to the field control effect of trialeurodes vaporariorum, application method is blade face
Even spraying.Per experimental plot using 5 points of samplings, every is investigated 2 plants, in 7 days statistics effect of chemical control, result of the test after medicine
It is shown in Table 6.
The field efficacy result of the trialeurodes vaporariorum of table 6
Remarks：A is avermectin B2a, and B is Nitenpyram, clothianidin or Diacloden.
It is right from table 6 as can be seen that avermectin B2a and clothianidin, Nitenpyram, Diacloden are in varing proportions after mixture
The preventive effect of trialeurodes vaporariorum is significantly improved, E-EOIt is all higher than 10%, substantially, prevention effect is good for synergistic effect, has and stronger promote the use of valency
Value.
To sum up described in indoor biometricses and field experiment result, the composition pesticide of the present invention containing avermectin B2a,
Good prevention effect is shown to insects such as nematode, aphid, trialeurodes vaporariorums, to Target crops safety, compared with single dose, synergy
Substantially.Composition pesticide of the present invention has the mechanism of action unique, and unit dose is few, many advantages, such as quick-acting is good, the lasting period is long,
With preferable promotional value.
Embodiment described above is only that the preferred embodiment of the present invention is described, but is not limited to this, this
The technical staff in field is easy to understand according to above-described embodiment the spirit of the present invention, and makes different amplifications and change, but
Without departing from the spirit of the present invention, all within protection scope of the present invention.
Claims (10)
1. a kind of composition pesticide containing avermectin B2a, it is characterised in that it includes component A and B component, the A groups
It is avermectin B2a to divide, and the B components are one kind in Diacloden, Nitenpyram or clothianidin；The A components and B groups
The mass ratio divided is 20:1~1:50.
2. a kind of composition pesticide containing avermectin B2a according to claim 1, it is characterised in that it also includes
Auxiliary agent C；The component A and B component account for the 1% ~ 80% of composition gross mass.
3. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is missible oil；The auxiliary agent C includes emulsifying agent, cosolvent and solvent, and the mass percent of each component is：A groups
Point 0.1 ~ 20%, B component 0.1 ~ 20%, emulsifying agent 5 ~ 15%, cosolvent 1 ~ 10%, solvent supplies 100%.
4. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is microemulsion；The auxiliary agent C includes emulsifying agent, solvent and water, and the mass percent of each component is：Component A
0.1 ~ 30%, B component 0.1 ~ 30%, emulsifying agent 5 ~ 20%, solvent 5% ~ 40%, water complements to 100%.
5. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is aqueous suspension agent；The auxiliary agent C includes wetting agent, dispersant, antifreezing agent, thickener, defoamer, pH values
Conditioning agent and water, the mass percent of each component is：Component A 0.1 ~ 50%, B component 0.1 ~ 50%, wetting agent 0 ~ 2%, dispersant 4 ~
20%, antifreezing agent 1 ~ 5%, thickener 0.01 ~ 2%, defoamer 0.1 ~ 0.8%, pH values conditioning agent 0.1 ~ 5%, water supplies 100%.
6. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is soluble liquid；The auxiliary agent C includes cosolvent, emulsifying agent and solvent, the mass percent of each component
For：Component A 0.1 ~ 10%, B component 0.1 ~ 30%, cosolvent 1 ~ 20%, emulsifying agent 1 ~ 20%, solvent complements to 100%.
7. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is granule；The auxiliary agent C includes wetting agent, dispersant, binding agent and carrier, the quality percentage of each component
Number is：Component A 0.1 ~ 50%, B component 0.1 ~ 50%, wetting agent 0.1 ~ 10%, dispersant 0.1 ~ 15%, binding agent 0.1 ~ 14%, carrier
Complement to 100%.
8. a kind of composition pesticide containing avermectin B2a according to claim 2, it is characterised in that the agricultural chemicals
The formulation of composition is water dispersible granules；The auxiliary agent C includes dispersant, wetting agent, disintegrant, binding agent and carrier, each group
Point mass percent be：Component A 1 ~ 80%, B component 1 ~ 80%, dispersant 0.1 ~ 15%, wetting agent 0.1 ~ 10%, disintegrant 0.1 ~
30%, binding agent 0.1 ~ 15%, carrier complements to 100%.
9. the purposes of a kind of composition pesticide as described in any one of claim 1 ~ 8, it is characterised in that for preventing and kill off pierce-suck type
The parasitic nematode of mouthpart insect and harm root system of plant.
10. the method that one kind prevents and kill off insect pest using the composition pesticide described in any one of claim 1 ~ 8, it is characterised in that will
The composition is dressed seed, sprayed, shedding or pouring root is applied to crop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201710383866.9A CN107258800A (en) | 2017-05-26 | 2017-05-26 | A kind of composition pesticide containing avermectin B2a |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710383866.9A CN107258800A (en) | 2017-05-26 | 2017-05-26 | A kind of composition pesticide containing avermectin B2a |
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| CN107258800A true CN107258800A (en) | 2017-10-20 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710383866.9A Withdrawn CN107258800A (en) | 2017-05-26 | 2017-05-26 | A kind of composition pesticide containing avermectin B2a |
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| CN (1) | CN107258800A (en) |
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| CN107439568A (en) * | 2017-09-19 | 2017-12-08 | 河北兴柏农业科技有限公司 | A kind of composition pesticide containing Avermectin B2 |
| CN111084190A (en) * | 2019-12-04 | 2020-05-01 | 河北威远生物化工有限公司 | Insecticidal composition containing emamectin benzoate B2a and application thereof |
| CN115399316A (en) * | 2022-09-15 | 2022-11-29 | 湖北省农业科学院植保土肥研究所 | Pesticide tank-mixed auxiliary composition and preparation method and application thereof |
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