CN107252365A - A kind of joint prosthesis femoral prosthesis and preparation method thereof - Google Patents
A kind of joint prosthesis femoral prosthesis and preparation method thereof Download PDFInfo
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- CN107252365A CN107252365A CN201710027176.XA CN201710027176A CN107252365A CN 107252365 A CN107252365 A CN 107252365A CN 201710027176 A CN201710027176 A CN 201710027176A CN 107252365 A CN107252365 A CN 107252365A
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- femoral prosthesis
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- joint prosthesis
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- 238000005495 investment casting Methods 0.000 claims description 8
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2825—Femur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3082—Grooves
- A61F2002/30827—Plurality of grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
- A61F2002/30891—Plurality of protrusions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2002/3093—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth for promoting ingrowth of bone tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30957—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using a positive or a negative model, e.g. moulds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of preparation method of joint prosthesis femoral prosthesis, including：First generate hole or groove on joint prosthesis femoral prosthesis body using various processing methods, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.Not only facilitate and lockmaking effect is formed between implant and bone tissue, the preferable space structure of offer can be grown into for new bone, be conducive to improving attachment, the Reproductive activity of bone and its cells, reach good synosteosis, joint prosthesis femoral prosthesis and the amalgamation of autologous tissue are enhanced, is conducive to joint prosthesis femoral prosthesis effectively to be played a role for a long time in human body；And excellent in mechanical performance, high mechanical strength, stress shielding can be reduced very well, keep Effective Mechanical Properties support.
Description
Technical field
The present invention relates to technical field of medical instruments, more particularly to a kind of orthopaedics implant joint prosthesis femoral prosthesis and its
Preparation method.
Background technology
The joint prosthesis disease caused by disease and wound is common disease clinically, is also the worldwide difficulty of orthopaedics therapy
One of topic, severely impacts the quality of life of patient.Joint prosthesis femoral prosthesis is current clinical practice more universal bone
Section's material.Extensive use of the joint prosthesis femoral prosthesis in orthopaedics therapy, significantly improves over clinical insurmountable
Problem and it is implanted to power and has also reached quite satisfied effect.Or existing joint prosthesis femoral prosthesis is using increasing material
Manufacturing technology forms certain mat surface on joint prosthesis femoral prosthesis body, otherwise manually closed using material manufacturing technology is subtracted
The structure such as generation hole on femoral prosthesis body is saved, but using increases material manufacturing technology or subtracts people prepared by material manufacturing technology merely
Bone Ingrowth effect between work joint femoral prosthesis and bone is bad, it is unstable to merge insufficient, long-term fixed effect, when serious
Cause operative failure or postoperative rehabilitation bad.
The content of the invention
The technical problems to be solved by the invention are to overcome the defect of above-mentioned prior art there is provided a kind of joint prosthesis femur
Prosthese and preparation method thereof, makes joint prosthesis femoral prosthesis strong with patient's sclerotin adhesion, is conducive to bone tissue to grow into, and can be achieved
Preferably biology fixed effect.
The technical problems to be solved by the invention are achieved by the following technical programs：
A kind of preparation method of joint prosthesis femoral prosthesis, including：First using various processing methods in joint prosthesis femoral prosthesis
Generate hole or groove on body, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
Further, the aperture in the hole is 50-10000 μm, and depth is 25-5000 μm；A width of 50-10000 μ of the groove
M, depth is 25-5000 μm.
Further, the post is prominent, ball is prominent or other three-dimensional shapes a height of 2-6000 μm, forms mat surface, is conducive to
Gegenbaur's cell creeping with it is fixed.
Further, the increases material manufacturing technology is 3D printing.
Further, the metal material vacuum lost wax casting that the joint prosthesis femoral prosthesis body passes through biocompatibility
Or forging is made.
Further, joint prosthesis femoral prosthesis body Yu human body bone Long Term Contact position Surface Creation hole or
Groove.
The present invention also provides a kind of joint prosthesis femoral prosthesis, is made of described preparation method.
The present invention has the advantages that：
（1）The present invention is on joint prosthesis femoral prosthesis body first using various processing methods in joint prosthesis femoral prosthesis body
Upper generation hole or groove, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove, combine and subtract
Material manufacturing technology and increases material manufacturing technology, compared to it is traditional only with subtract material manufacturing technology generation hole, and it is traditional only
Using increases material manufacturing technology formation mat surface, the surface area of joint prosthesis femoral prosthesis and synosteosis increases 5-10 times, does not only have
Help form lockmaking effect between joint prosthesis femoral prosthesis and bone tissue, the preferable space knot of offer can be grown into for new bone
Structure, is conducive to improving attachment, the Reproductive activity of bone and its cells, reaches good synosteosis, enhance joint prosthesis femur false
Body and the amalgamation of autologous tissue, are conducive to joint prosthesis femoral prosthesis effectively to be played a role for a long time in human body；And power
Excellent performance is learned, high mechanical strength can reduce stress shielding very well, keep Effective Mechanical Properties support.
（2）Process is simple, controllability is strong, easy to operate.
Brief description of the drawings
Fig. 1 is top view of the invention；
Fig. 2 is side view of the invention.
In figure：1st, joint prosthesis femoral prosthesis, 2, hole, 3, post dashes forward.
Embodiment
With reference to embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention,
It is not limitation of the invention.
In the preparation method of the joint prosthesis femoral prosthesis of the present invention, first using various processing methods in joint prosthesis femur
Generate hole or groove on prosthese body, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other three-dimensional shapes in hole or groove.
The various processing methods are known in the art any can generate hole on joint prosthesis femoral prosthesis body
Or the processing method of groove, such as casting, forging, lf, acid corrosion.
The increases material manufacturing technology is preferred but is not limited to 3D printing.
The joint prosthesis femoral prosthesis body is preferred but is not limited to take off by the metal material vacuum of biocompatibility
Wax is cast or forging is made, and wherein the metal material of biocompatibility is preferred but is not limited to titanium alloy, cochrome, wherein titanium
Alloy includes Ti-8Fe-8Ta-4Zr, and Ti-8Fe-8Ta-4Zr greatly reduces modulus of elasticity compared to traditional titanium alloy, can
To obtain the excellent results in terms of engineering properties and biocompatibility.
Embodiment 1
A kind of joint prosthesis femoral prosthesis, its preparation method includes：Vacuum lost wax casting manufacturer is used by vitallium
Work joint femoral prosthesis body, it is then long in the joint prosthesis femoral prosthesis body and human body bone using lf method
Phase contact site surface on generation hole or groove, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；Should
Lf method uses prior art, and the aperture for making hole is 50 μm, and depth is 25 μm, makes a width of 50 μm of groove, and depth is 25 μm；Should
3d printing techniques use prior art, make that post is prominent, ball is prominent or other three-dimensional shapes a height of 2 μm.
Embodiment 2
A kind of joint prosthesis femoral prosthesis, its preparation method includes：Vacuum lost wax casting manufacturer is used by vitallium
Work joint femoral prosthesis body, it is then long in the joint prosthesis femoral prosthesis body and human body bone using lf method
Phase contact site surface on generation hole or groove, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；Should
Lf method uses prior art, and the aperture for making hole is 10000 μm, and depth is 5000 μm, makes a width of 10000 μm of groove, deep
For 5000 μm；The 3d printing techniques use prior art, make that post is prominent, ball is prominent or other three-dimensional shapes a height of 6000 μm.
Embodiment 3
A kind of joint prosthesis femoral prosthesis, its preparation method includes：Vacuum lost wax casting manufacturer is used by vitallium
Work joint femoral prosthesis body, it is then long in the joint prosthesis femoral prosthesis body and human body bone using lf method
Phase contact site surface on generation hole or groove, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；Should
Lf method uses prior art, and the aperture for making hole is 1000 μm, and depth is 1000 μm, makes a width of 1000 μm of groove, depth is
3000μm；The 3d printing techniques use prior art, make that post is prominent, ball is prominent or other three-dimensional shapes a height of 500 μm.
Embodiment 4
A kind of joint prosthesis femoral prosthesis, its preparation method includes：Vacuum lost wax casting manufacturer is used by vitallium
Work joint femoral prosthesis body, then using acid corrosion method used long-term in the joint prosthesis femoral prosthesis body and human body bone
Generate hole or groove on the surface of contact site, then builds using 3D printing that post is prominent, ball is dashed forward or other three-dimensional shapes in hole；It is described
Acid corrosion is operated：Joint prosthesis femoral prosthesis body is first 15% hydrofluoric acid treatment 5-60 seconds with concentration, is then with concentration
65% nitric acid is handled 1-10 minutes at 75 DEG C, then is then taken out with the hydrochloric acid that concentration is 36% in being handled 1-5 minutes at 70 DEG C
Cleaned using distilled water or deionized water；The aperture in the hole is 100-6000 μm, and depth is 500-3000 μm；The groove
A width of 500-3000 μm, depth is that the 100-2000 μm of 3d printing technique uses prior art, post is dashed forward, ball is dashed forward or other solid figures
A height of 2000 μm of shape.
Comparative example 1
A kind of joint prosthesis femoral prosthesis, its preparation method is：Vacuum lost wax casting manufacture of intraocular is used by vitallium
Joint femoral prosthesis body.
Comparative example 2
A kind of joint prosthesis femoral prosthesis, its preparation method includes：Vacuum lost wax casting manufacturer is used by vitallium
Work joint femoral prosthesis body, it is then long in the joint prosthesis femoral prosthesis body and human body bone using lf method
Phase contact site surface on generate multiple holes；The aperture in the hole is 50-10000 μm, and depth is 25-5000 μm.
Detection project：
A. BGP generation test
MC3T3-E1 Gegenbaur's cells derive from the skull of newborn mice, and cell culture medium is α-MEM culture mediums, wherein containing
10% hyclone, 100U/ml green grass or young crops/streptomysin, 0.05g/L ascorbic acid and 10mmol/L β-sodium glycero-phosphate.It will implement
Orthopaedics implant prepared by example 1-4 and comparative example 1-2 is respectively put into 24 orifice plates, is stayed overnight using the sterilizing of 70% ethanol, uses phosphoric acid
Salt buffer (PBS) is washed 3 times, and is sterilized 2 hours with ultraviolet irradiation.Test and be inoculated with 10 in every hole of 24 orifice plates5Individual cell,
Keeping temperature is 37 DEG C, contains 5% CO2 in atmosphere, continues to collect supernatant after cultivating 14 days, uses BGP ELISA kit
Detect the content of BGP in supernatant.Unit：ng/mL.
B. tensile strength
According to YY 0117.3, tensile strength survey is carried out to joint prosthesis femoral prosthesis prepared by embodiment 1-4 and comparative example 1-2
Examination.Unit：Rm/MPa.
Embodiment described above only expresses embodiments of the present invention, and it describes more specific and detailed, but can not
Therefore the limitation to the scope of the claims of the present invention is interpreted as, as long as the skill obtained using the form of equivalent substitution or equivalent transformation
Art scheme, all should fall within the scope and spirit of the invention.
Claims (5)
1. a kind of preparation method of joint prosthesis femoral prosthesis, it is characterised in that including：First using various processing methods artificial
Generate hole or groove on the femoral prosthesis body of joint, then builds using increases material manufacturing technology that post is prominent, ball is dashed forward or other in hole or groove
Three-dimensional shape.
2. the preparation method of joint prosthesis femoral prosthesis as claimed in claim 1, it is characterised in that the aperture in the hole is
50-10000 μm, depth is 25-5000 μm；A width of 50-10000 μm of the groove, depth is 25-5000 μm.
3. the preparation method of joint prosthesis femoral prosthesis as claimed in claim 1, it is characterised in that the post is prominent, ball is prominent or
A height of 2-6000 μm of other three-dimensional shapes.
4. the preparation method of joint prosthesis femoral prosthesis as claimed in claim 1, it is characterised in that the joint prosthesis femur
Prosthese body is made up of the metal material vacuum lost wax casting or forging of biocompatibility.
5. a kind of joint prosthesis femoral prosthesis, is made of the preparation method described in claim any one of 1-4.
Priority Applications (1)
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| CN201710027176.XA CN107252365A (en) | 2017-01-16 | 2017-01-16 | A kind of joint prosthesis femoral prosthesis and preparation method thereof |
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| CN201710027176.XA CN107252365A (en) | 2017-01-16 | 2017-01-16 | A kind of joint prosthesis femoral prosthesis and preparation method thereof |
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| CN107252365A true CN107252365A (en) | 2017-10-17 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111166532A (en) * | 2019-12-30 | 2020-05-19 | 武汉联影智融医疗科技有限公司 | Artificial joint and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0827726A2 (en) * | 1996-09-04 | 1998-03-11 | Implantech Medizintechnik Ges.m.b.H. | Implant, especially prosthetic joint implant |
| JP2007296250A (en) * | 2006-05-06 | 2007-11-15 | Osaka Univ | Medical implant and artificial joint using thereof |
| US20130158672A1 (en) * | 2010-06-18 | 2013-06-20 | 4-Web, Inc. | Bone implant interface system and method |
| WO2015144129A1 (en) * | 2014-03-24 | 2015-10-01 | Ghv Schmiedetechnik Gmbh | Femur component of a hip joint prosthesis and method for producing a femur component of a hip joint prosthesis |
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2017
- 2017-01-16 CN CN201710027176.XA patent/CN107252365A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0827726A2 (en) * | 1996-09-04 | 1998-03-11 | Implantech Medizintechnik Ges.m.b.H. | Implant, especially prosthetic joint implant |
| JP2007296250A (en) * | 2006-05-06 | 2007-11-15 | Osaka Univ | Medical implant and artificial joint using thereof |
| US20130158672A1 (en) * | 2010-06-18 | 2013-06-20 | 4-Web, Inc. | Bone implant interface system and method |
| WO2015144129A1 (en) * | 2014-03-24 | 2015-10-01 | Ghv Schmiedetechnik Gmbh | Femur component of a hip joint prosthesis and method for producing a femur component of a hip joint prosthesis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111166532A (en) * | 2019-12-30 | 2020-05-19 | 武汉联影智融医疗科技有限公司 | Artificial joint and preparation method thereof |
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