CN107233235A - Facial mask is repaired in a kind of deep layer purification - Google Patents

Facial mask is repaired in a kind of deep layer purification Download PDF

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Publication number
CN107233235A
CN107233235A CN201710649816.0A CN201710649816A CN107233235A CN 107233235 A CN107233235 A CN 107233235A CN 201710649816 A CN201710649816 A CN 201710649816A CN 107233235 A CN107233235 A CN 107233235A
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CN
China
Prior art keywords
facial mask
magnetite
deep layer
repaired
fulvic acid
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Application number
CN201710649816.0A
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Chinese (zh)
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不公告发明人
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Foshan Sanshui Jiahua Chemical Research Institute (general Partnership)
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Foshan Sanshui Jiahua Chemical Research Institute (general Partnership)
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Priority to CN201710649816.0A priority Critical patent/CN107233235A/en
Publication of CN107233235A publication Critical patent/CN107233235A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

Facial mask is repaired the invention discloses a kind of purification of deep layer, it includes the composition of following mass percent:Fulvic acid 0.4~0.8%, magnetite 0.5~1.5%, albumin polypeptide 0.5~1.5%, diatomite 5~15%, glycerine 4~8%, carbomer 0.1~0.5%, cetostearyl alcohol 2~6%, the stearates 0.1~1% of stearine/PEG 100, the smooth stearate 0.5~2% of sorb, kaolin 5~15%, polysorbate60 0.2~2%, dipotassium glycyrrhizinate 0.04~0.06%, beta glucan 0.01~1%, Phenoxyethanol 0.25~0.5%, triethanolamine 0.02~0.08%, Sodium Hyaluronate 0.01~0.1%, deionized water surplus.Product of the present invention can adsorb skin surface dirt and fixed contents of many kinds of heavy metal ion, and deep layer cleaning is done to the dirt and toxin of fine hair hole, make skin clean fine and smooth, the effect of purification skin is reached, while also antiinflammatory action;It is salubrious clean after use and gentle non-stimulated, human body is had no side effect, it is smooth that long-term use can make skin more compact.

Description

Facial mask is repaired in a kind of deep layer purification
Technical field
The present invention relates to cosmetic field, and in particular to facial mask is repaired in a kind of deep layer purification.
Background technology
Facial mask is the important content in skin nursing, for the regular application facial mask of all kinds of skin characteristics, can make oiliness skin Skin degreasing, thick pore is restrained, and the skin for the gauffer that dries up recovers gloss, and the inflammation of dark sore skin is inhibited.Facial mask Skin is set to seem salubrious, smooth and pure white delicacy after use, because when facial mask is coated on skin, facial mask is produced with skin Affinity, with gradually drying for facial mask, skin temperature rise, blood circulation quickening, skin-tightening, tension force is strengthened, skin secretion Sebum and moisture reverse osmosis unfold epidermis softness, pore opens in cuticula, and the active ingredient in facial mask is penetrated into skin and inhaled by it Receive, while facial mask is tightly connected with skin, when removing facial mask, the aging cutin on skin, the dirt in pore are also by simultaneously Under band, make skin pure and fresh clean.Through retrieval, fulvic acid, magnetite, albumin polypeptide combination cosmetic formulations are not made an addition into also In Patents and report, and fulvic acid, magnetite, albumin polypeptide have Adsorption of Heavy Metals, anti-inflammatory, it is anti-oxidant the effects such as make It has broad application prospects in cosmetic field.
The content of the invention
Based on this, facial mask is repaired it is an object of the invention to provide a kind of purification of deep layer, it is with fulvic acid, magnetite, white egg White polypeptide three is that main composition is made an addition in face pack prescription, can make skin pure and fresh clean after use.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of deep layer purification repairs facial mask and contains fulvic acid, magnetite, three kinds of compositions of albumin polypeptide, and respective quality hundred Divide ratio as follows:
Fulvic acid:0.4~0.8%
Magnetite:0.5~1.5%
Albumin polypeptide:0.5~1.5%.
It is preferred that, described fulvic acid, magnetite, albumin polypeptide mass percent it is as follows:
Fulvic acid:0.5~0.7%
Magnetite:0.7~1.2%
Albumin polypeptide:0.7~1.2%.
It is optimal, described fulvic acid, magnetite, albumin polypeptide mass percent it is as follows:
Fulvic acid:0.6%
Magnetite:1%
Albumin polypeptide:1%.
Further, described magnetite is prepared as follows:Loadstone raw material is taken, by tentatively sieving the removal of impurity After crush, after crushing cross 20 mesh sieves in 60 DEG C dry one hour, dry terminate after be warming up to 700 DEG C with 4% vinegar to raw material Carry out 2 hours acid to quench, acid, which is quenched, to be terminated to be crushed and crossed 40 mesh sieves again, obtains the magnetite.
Further, described albumin polypeptide is prepared as follows:
1) fresh hen egg egg white is taken, and is dissolved with organic solvent deposit agent, centrifugation obtains supernatant;Using cold acetone dissolving not Molten thing, is centrifuged again after being sufficiently stirred for;
2) merge and centrifuge resulting sediment twice, the sediment is ovalbumin crude product;
3) sediment is dissolved in after water and is digested using complex enzyme, then heating inactivates enzyme, finally filters, takes filtrate Concentration vacuum drying, obtained product is albumin polypeptide product.
Further, facial mask is repaired in the purification of described deep layer also includes the composition of following mass percent:Diatomite 5~ 15%th, glycerine 4~8%, carbomer 0.1~0.5%, cetostearyl alcohol 2~6%, stearine/PEG-100 stearic acid The smooth stearate 0.5~2% of ester 0.1~1%, sorb, kaolin 5~15%, polysorbate -600.2~2%, glycyrrhizic acid Dipotassium 0.04~0.06%, beta glucan 0.01~1%, Phenoxyethanol 0.25~0.5%, triethanolamine 0.02~0.08%, Sodium Hyaluronate 0.01~0.1%, deionized water surplus.
Several functional components in the present invention are introduced below:
Humic acid material is a class natural macromolecular organic matter, including fulvic acid, humic acid or humic acid, humic acid, It is widely present in water body and soil.Humus accounts for half of contained total amount of organic or so in general water body, and what is had is reachable 80%, wherein fulvic acid accounts for 83-90%, and humic acid or humic acid account for 3-4%, and humic acid accounts for 7-13%.Thus fulvic acid is water The main body of humus in body.Fulvic acid surface includes substantial amounts of active group, and fulvic acid is based on aromatic group, containing a large amount of Hydroxyl, carboxyl, carbonyl.These functional structures contribute to fulvic acid to be complexed with heavy metal ion.In addition, fulvic acid surface band There is larger elecrtonegativity, the series reaction between fulvic acid and heavy metal ion can be promoted.Both it had been dissolved in fulvic acid, soil dilute Alkali, is dissolved in the humic acid of the yellowish-brown of diluted acid again.Carbon containing, nitrogen negligible amounts, and hydrogen, oxygen are then height compared with humic acid.But dissociation Degree is larger.Its stability is less than humic acid.
Magnet is traditional Chinese medicine (i.e. mineral drug), and main product is in Hebei, Shandong, Liaoning, Jiangsu, Guangdong and other places, for oxidation Species mineral spinelle race magnetic iron ore, main (Fe3O4) containing ferroso-ferric oxide, also known as magnetite are last, profound stone, kind stone, ling magnet, hero magnetic Stone, magnetic.Magnetite first recorded in《Sheng Nong's herbal classic》, middle product are classified as, are carried " pungent, cold.Pain, can not hold in main general arthralgia rheumatism, podomere Thing, washes acid and disappears, except big hot dysphoria and deafness ", its taste is salty, cold in nature.Return liver, the heart, kidney channel, with calming the liver, tranquillizing the mind by relieving convulsion, Effect that hearing-improing and eyesight improving, gas of receiving are relievingd asthma.Research shows that magnetite has anti-inflammatory, analgesia, hemostasis-coagulation effect, with the traditional Chinese medical science on magnetite Effect is corresponding.
Albumin polypeptide is main protein in egg white through different enzyme (pepsin, trypsase, pancreas curdled milk Protease) obtained product after enzymolysis, its molecular weight is less than 3000Da, albumin polypeptide by different aminoacids sequence peptides group Into, show extensive physiological regulation function, including regulation immune function of human body, Angiotensin-Converting (Angiotensin--convertingenzyme, ACE) suppress function, protection renal function, capture free radical, it is anti-oxidant should The effects such as swashing anti-aging, regulation gastrointestinal function, getting rid of illness, diseases prevention, anti-aging, build up health, have additional nutrients in terms of, have Wide application prospect.In albumin polypeptide fragment sequence in Ala-His, Val-His and Val-His-Ala-Asp-Glu-Asu Histidine sequences can suppress peroxidating of the free radical to liposome (liposomas) phosphatidyl choline, protect immunocyte film, drop Low Cellular peroxide levels eliminate the excessive free radicals generated in immune response pathway and influence the immunologic function of body.
Compared with prior art, the device have the advantages that as follows:Product of the present invention it is main by fulvic acid, magnetite, Albumin polypeptide is constituted in specific proportions, toxin expelling, Adsorption of Heavy Metals is carried out by fulvic acid and magnetite synergy, than common Facial mask has more adsorption capacity, can adsorb skin surface dirt and fixed contents of many kinds of heavy metal ion, dirt to fine hair hole and Toxin does deep layer cleaning, makes skin clean fine and smooth, reaches the effect of purification skin.Magnetite promotees to the antiinflammatory action of skin simultaneously Make that skin can be protected in use, the addition of albumin polypeptide can suppress mistake of the free radical to liposomal phospholipids phatidylcholine Oxidation, protects immunocyte film, reduces Cellular peroxide levels, repairs skin, prevents skin aging, skin is got well State.It is salubrious clean after facial mask use of the present invention and gentle non-stimulated, human body is had no side effect, long-term use can make skin more Step up cause smooth.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated:
The facial mask embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
1st, the preparation method of magnetite of the invention is as follows:
Loadstone raw material is taken, is crushed by tentatively sieving after the removal of impurity, 20 mesh sieves are crossed after crushing and dry one in 60 DEG C Hour, drying is warming up to 700 DEG C and raw material 2 hours acid of progress is quenched with 4% vinegar after terminating, acid, which is quenched, to be terminated to be crushed again And 40 mesh sieves are crossed, obtain the magnetite.
2nd, the preparation method of albumin polypeptide of the invention is as follows:
1) fresh hen egg egg white is taken, and is dissolved with organic solvent deposit agent, centrifugation obtains supernatant;Using cold acetone dissolving not Molten thing, is centrifuged again after being sufficiently stirred for;
2) merge and centrifuge resulting sediment twice, the sediment is ovalbumin crude product;
3) sediment is dissolved in after water and is digested using complex enzyme, then heating inactivates enzyme, finally filters, takes filtrate Concentration vacuum drying, obtained product is albumin polypeptide product.
Comparative example 1:
Difference with embodiment 3 is only to be free of fulvic acid, and remaining each group material addition, preparation does not change with technique.
Comparative example 2:
Difference with embodiment 3 is only to be free of magnetite, and remaining each group material addition, preparation does not change with technique.
Comparative example 3:
Difference with embodiment 3 is only to be free of albumin polypeptide, and remaining each group material addition, preparation does not change with technique Become.
Comparative example 4:
Difference with embodiment 3 is only to be free of fulvic acid, 3 kinds of compositions of magnetite and albumin polypeptide, and remaining each group material adds Plus, preparation does not change with technique.
Efficacy validation
Adsorption of Heavy Metals is verified:
Embodiment 1-5 and comparative example 1-3 facial mask liquid is prepared, the facial mask of Adsorption of Heavy Metals effect is laid claim on the market, point Not by film liquid, copper-bath with 0.1mg/L:10mmol/L proportioning is added in 10ml centrifuge tubes, and its ph is adjusted with PBS solution For 6,12h is shaken at room temperature, is centrifuged, and is separately added into the lead nitrate solution of equivalent, nitric acid cadmium solution, nitric acid mercury solution and is carried out Adsorption test, 20min, 40min, 60min measure test agent for the adsorption capacity of lead ion, the adsorption capacity of cadmium ion, The adsorption capacity of mercury ion, as a result such as table 2 below.
Table 2
From table 2 it can be seen that the corresponding film liquids of embodiment 1-5 have the characteristic of adsorbing heavy metal cadmium, lead, mercury, comparative example 1-3 It is one or more in fulvic acid, magnetite and albumin polypeptide because lacking, cause absorption affinity poor;With laying claim to an absorption huge sum of money on the market The facial mask of category is compared, and product heavy metal of the invention has the suction-operated of conspicuousness.
In order to further verify effect of facial mask of the present invention, choose embodiment 1~5 and comparative example 1~4 carries out investigation on probation And evaluation test.
Object on probation:Trier is healthy all right, without lactation or pregnancy period, shows as face after heavy metal poisoning Allergy, long spot, inflammation crowd.
Embodiment is as follows:Every group of 30 people are chosen to be tested.Experimenter uses corresponding 22-24 product every night Corresponding trial target is used between point, each sampling phase was one month, at the 30th day, experimenter is imitated to Adsorption of Heavy Metals Fruit carries out self-appraisal, and self-appraisal is carried out to the cleaning action of facial mask;Whole people complete whole experiment in process of the test, and require Everyone must not use other any skin-protection products at honest report in result of the test, experimentation.
Using the clinical evaluation of skin quality, the result of the test such as table 3 below of Adsorption of Heavy Metals.
Table 3
As can be seen from Table 3, the present invention is to face's allergy, long spot, and the skin problem of inflammation, the composition of embodiment has substantially Improvement result, and because lacking the one or more in fulvic acid, magnetite and albumin polypeptide in comparative example, cause effect to be failed to understand It is aobvious, or even to no effect;In addition, the experimenter for having 83.3% thinks that the facial mask of the present invention has excellent cleaning skin effect, energy Maintain the health status of skin.
Senile-resistant efficacy is verified:
Choose healthy volunteer 180,30~65 years old age;There is certain Dermatochalasia/fine wrinkles phenomenon, and voluntarily Experiment is completed on request;Test products are embodiment 1-5 and comparative example 1-4 product;Test period was 4 week, and in examination Test first 0 week, test 2 weeks, water content, skin elasticity and the wrinkle score value of 4 weeks detection keratodermas of experiment.
Method of testing:(1) moisture measurement:Left and right cheek position water content of stratum corneum, measurement 4 are measured using moisture tester It is secondary to average;(2) flexibility test:The elasticity of skin is measured with skin elasticity tester, accounting takes R2Average value, R2Value more connects Nearly 1, illustrate that elasticity is better;(3) face imaging:Subject's face is taken pictures (just using VISIA facial Image analysis systems Face, 45 ° of directions of left and right side) wrinkle assay value and texture score value are extracted, average, test result such as table 4 below.
Table 4
As can be seen from Table 4, after using the product of embodiment, the water content of keratoderma, skin elasticity, which have, to be continued Increase, illustrating the product of the present invention has excellent water conservation, reduces the effect of wrinkle;Carry out analysis product from wrinkle score value, can To further illustrate that the product of the present invention has anti-aging effects, and generation skin-tolerant will not be used because of long-time.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention System;It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies Decorations, the equivalent embodiment as equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention With modification, belong in the range of technical solution of the present invention.

Claims (6)

1. facial mask is repaired in a kind of purification of deep layer, it is characterised in that described deep layer purification repair facial mask contain fulvic acid, magnetite, Three kinds of compositions of albumin polypeptide, and respective mass percent is as follows:
Fulvic acid:0.4~0.8%
Magnetite:0.5~1.5%
Albumin polypeptide:0.5~1.5%.
2. facial mask is repaired in a kind of deep layer purification according to claim 1, it is characterised in that described fulvic acid, magnetite, white The mass percent of polypeptide is as follows:
Fulvic acid:0.5~0.7%
Magnetite:0.7~1.2%
Albumin polypeptide:0.7~1.2%.
3. facial mask is repaired in a kind of deep layer purification according to claim 2, it is characterised in that described fulvic acid, magnetite, white The mass percent of polypeptide is as follows:
Fulvic acid:0.6%
Magnetite:1%
Albumin polypeptide:1%.
4. facial mask is repaired in a kind of deep layer purification according to any one of claims 1 to 3, it is characterised in that described magnetite It is prepared as follows:Loadstone raw material is taken, is crushed by tentatively sieving after the removal of impurity, 20 mesh sieves are crossed after crushing in 60 DEG C Drying one hour, drying is warming up to 700 DEG C and raw material 2 hours acid of progress is quenched with 4% vinegar after terminating, acid, which is quenched, to be terminated to enter again Row is crushed and crosses 40 mesh sieves, obtains the magnetite.
5. facial mask is repaired in a kind of deep layer purification according to any one of claims 1 to 3, it is characterised in that described white egg White polypeptide is prepared as follows:
1) fresh hen egg egg white is taken, and is dissolved with organic solvent deposit agent, centrifugation obtains supernatant;Dissolve insoluble using cold acetone Thing, is centrifuged again after being sufficiently stirred for;
2) merge and centrifuge resulting sediment twice, the sediment is ovalbumin crude product;
3) sediment is dissolved in after water and is digested using complex enzyme, then heating inactivates enzyme, finally filters, takes filtrate to concentrate Vacuum drying, obtained product is albumin polypeptide product.
6. facial mask is repaired in a kind of deep layer purification according to any one of Claims 1 to 5, it is characterised in that described deep layer Facial mask is repaired in purification also includes the composition of following mass percent:Diatomite 5~15%, glycerine 4~8%, carbomer 0.1~ 0.5%th, the smooth stearate 0.5 of cetostearyl alcohol 2~6%, stearine/PEG-100 stearates 0.1~1%, sorb ~2%, kaolin 5~15%, polysorbate -600.2~2%, dipotassium glycyrrhizinate 0.04~0.06%, beta glucan 0.01 ~1%, Phenoxyethanol 0.25~0.5%, triethanolamine 0.02~0.08%, Sodium Hyaluronate 0.01~0.1%, deionized water Surplus.
CN201710649816.0A 2017-08-01 2017-08-01 Facial mask is repaired in a kind of deep layer purification Withdrawn CN107233235A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107669556A (en) * 2017-11-07 2018-02-09 广州市汇吉科技企业孵化器有限公司 A kind of whitening mud film
CN107854417A (en) * 2017-11-07 2018-03-30 广州市汇吉科技企业孵化器有限公司 A kind of anti-aging adsorbed film
CN107854341A (en) * 2017-12-11 2018-03-30 广州市汇吉科技企业孵化器有限公司 A kind of nose patch adsorbed film for adsorbing heavy metal
CN109700738A (en) * 2019-02-22 2019-05-03 天津尚美化妆品有限公司 A kind of magnetic facial mask and preparation method thereof with anti-aging effects

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107669556A (en) * 2017-11-07 2018-02-09 广州市汇吉科技企业孵化器有限公司 A kind of whitening mud film
CN107854417A (en) * 2017-11-07 2018-03-30 广州市汇吉科技企业孵化器有限公司 A kind of anti-aging adsorbed film
CN107854341A (en) * 2017-12-11 2018-03-30 广州市汇吉科技企业孵化器有限公司 A kind of nose patch adsorbed film for adsorbing heavy metal
CN109700738A (en) * 2019-02-22 2019-05-03 天津尚美化妆品有限公司 A kind of magnetic facial mask and preparation method thereof with anti-aging effects

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Application publication date: 20171010