CN107224442A - A kind of preparation method of quantum selenium solution - Google Patents
A kind of preparation method of quantum selenium solution Download PDFInfo
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- CN107224442A CN107224442A CN201710432166.4A CN201710432166A CN107224442A CN 107224442 A CN107224442 A CN 107224442A CN 201710432166 A CN201710432166 A CN 201710432166A CN 107224442 A CN107224442 A CN 107224442A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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Abstract
The present invention relates to quantum selenium field, particularly a kind of preparation method of quantum selenium solution, using hydrogen selenite as selenium source, by adding chitosan oligosaccharide solution and GSH, with superconducting magnet, resonated and stirred using magnetic force 2.4T 7T, L-type ascorbic acid is added while stirring, after stirring, it is finally most fast only to need that the preparation of quantum selenium solution is completed in 3 hours again through magnetic force 2.4T 19T quantum storehouse high-frequency resonance, and conventional method then needs can just complete for 48 hours, the time prepared needed for quantum selenium solution greatly is shortened, preparation efficiency is improved.
Description
Technical field
The present invention relates to quantum selenium field, particularly a kind of preparation method of quantum selenium solution.
Background technology
Quantum selenium（selenium）It is a kind of multi-functional life nutritional element, free radical, anti-oxidant, strength can be removed and suppressed
The generation of lipid peroxide, enhancing immunologic function, protection biological cell membrane, enhancing prostate regulatory function, prevent blood clot, it is clear
Except cholesterol, with being acted on insulin identical, the ability of cellular uptake sugar can be obviously promoted, stimulating circulation prevents skin
Skin aging, reduction carcinogen lure it is carcinous, eliminate vivo mutations cancer cells, prevent cancer cell division with growth etc..
Traditional quantum selenium solution preparation side is permanent magnet or electromagnetism ferro resonance, using below magnetic force 2.4T, it is necessary to 48
Hour could prepare completion, and elapsed time is longer, and preparation efficiency is low.
The content of the invention
It is an object of the invention to provide a kind of preparation method of quantum selenium solution, quantum selenium can greatly be shortened by changing method
Preparation time, improve preparation efficiency.
The present invention solve its technical problem use technical scheme be：A kind of preparation method of quantum selenium solution, it includes
Following steps：
（1）Using hydrogen selenite as selenium source, the selenous acid that concentration is 0.8 × 10^ (- 3) mol/L-1.2 × 10^ (- 3) mol/L is produced
Hydrogen sodium solution；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.3 ‰ -0.5 ‰ in obtained sodium selenite solution are 7.8 × 10
^ (- 3) mol/L-8.2 × 10^ (- 3) mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 8-12：
1, GSH and sodium selenite solution amount of substance ratio be 3-5:1；
（3）Using 2.4T-7T magnetic force carry out magnetic agitation, while stirring add L-type ascorbic acid, L-type ascorbic acid with
The mass ratio of sodium selenite solution is 1.5-2.5：1, mixing time is 3-15 hours, in 20 DEG C -30 DEG C of temperature strip during stirring
Carried out under part, selenium solution containing zeroth order is prepared in reduction；
（4）The high-frequency resonance in quantum storehouse by 7T-19T magnetic force of selenium solution containing zeroth order, prepares the quantum of less than 70 hertz
Selenium solution, resonance time is 60-120 seconds.
The concentration of described hydrogen selenite sodium solution is 1 × 10^ (- 3) mol/L.
The concentration of described chitosan oligosaccharide solution is 0.4 ‰.
Described GSH concentration is 8 × 10^ (- 3) mol/L.
Described chitosan oligosaccharide solution and the mass ratio of sodium selenite solution are 10：1.
Described GSH and the amount of substance ratio of sodium selenite solution are 4:1.
Described L-type ascorbic acid and the mass ratio of sodium selenite solution are 2：1.
Magnetic agitation is carried out using 7T magnetic force in described step three, mixing time is 3 hours, and temperature during stirring is
25℃。
In described step four selenium solution containing zeroth order by 19T magnetic force the high-frequency resonance in quantum storehouse, resonance time is
60 seconds.
Beneficial effects of the present invention：Using hydrogen selenite as selenium source, by adding chitosan oligosaccharide solution and GSH, superconducting magnetic is used
Iron, is resonated using magnetic force 2.4T-7T and stirred, L-type ascorbic acid is added while stirring, after stirring, then through magnetic force 2.4T-19T
Quantum storehouse high-frequency resonance, it is finally most fast only to need to complete for 3 hours the preparation of quantum selenium solution, and conventional method then need it is 48 small
Shi Caike is completed, and is greatly shortened the time prepared needed for quantum selenium solution, is improved preparation efficiency.
Embodiment
Embodiment 1
A kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the selenous acid that concentration is 0.8 × 10^ (- 3) mol/L-1.2 × 10^ (- 3) mol/L is produced
Hydrogen sodium solution；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.3 ‰ -0.5 ‰ in obtained sodium selenite solution are 7.8 × 10
^ (- 3) mol/L-8.2 × 10^ (- 3) mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 8-12：
1, GSH and sodium selenite solution amount of substance ratio be 3-5:1；
（3）Using 2.4T-7T magnetic force carry out magnetic agitation, while stirring add L-type ascorbic acid, L-type ascorbic acid with
The mass ratio of sodium selenite solution is 1.5-2.5：1, mixing time is 3-25 hours, in 20 DEG C -30 DEG C of temperature strip during stirring
Carried out under part, selenium solution containing zeroth order is prepared in reduction；
（4）The high-frequency resonance in quantum storehouse by 7T-19T magnetic force of selenium solution containing zeroth order, prepares the quantum of less than 70 hertz
Selenium solution, resonance time is 60-120 seconds.
Quantum storehouse is prior art, commercially available on the market, and what is applied in the present embodiment is the ecology production of Ankang City zinc selenium
The quantum storehouse equipment of industry research institute production.
GSH is that glutathione is the tripeptide compound being combined into by glutamic acid, cysteine and glycine.
The present invention, by adding chitosan oligosaccharide solution and GSH, with superconducting magnet, uses magnetic force using hydrogen selenite as selenium source
2.4T-7T resonance stirrings, add L-type ascorbic acid while stirring, after stirring, then common through magnetic force 2.4T-19T quantum storehouse high frequency
Shake, it is finally most fast only to need that the preparation of quantum selenium solution is completed in 3 hours, and conventional method then needs can just complete for 48 hours,
The time prepared needed for quantum selenium solution greatly is shortened, preparation efficiency is improved.
The quantum selenium solution for less than 70 hertz prepared using the method for the invention is by quantum storehouse resonance technique
And special process is developed, and it with the addition of the necessary biological magnetic field of customized human body.Prepared using this method
Quantum selenium solution product can exclude intracorporeal organ to the intracellular timely circulation for supplementing the nutrients, promoting normal gene information ripple
And the waste of intracellular accumulation, reach thoroughly clear Xian's intraor extracellular environment, activation just aging cell and improve cell
The effect of activity, relative to quantum selenium resistance cancer, reduces miocardial infarction and anginal generation, to hepatopathy, nephrotic side
Help the effects such as liver decomposition is with rubbish produced during exclusion toxin, removing body metabolism to serve and further promote work
With.
Embodiment 2
A kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the hydrogen selenite sodium solution that concentration is 0.8 × 10^ (- 3) mol/L is produced；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.3 ‰ in obtained sodium selenite solution are 7.8 × 10^ (- 3)
Mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 12：1, GSH and the material of sodium selenite solution
Amount is than being 5:1；
（3）Magnetic agitation is carried out using 2.4T magnetic force, L-type ascorbic acid, L-type ascorbic acid and sub- selenium are added while stirring
The mass ratio of acid sodium solution is 2.5：1, mixing time is 25 hours, is carried out during stirring under 20 DEG C of temperature conditionss, reduction system
It is standby go out selenium solution containing zeroth order；
（4）The high-frequency resonance in quantum storehouse by 7T magnetic force of selenium solution containing zeroth order, the quantum selenium for preparing less than 70 hertz is molten
Liquid, resonance time is 120 seconds.
Embodiment 3
A kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the hydrogen selenite sodium solution that concentration is 1.2 × 10^ (- 3) mol/L is produced；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.5 ‰ in obtained sodium selenite solution are 8.2 × 10^ (- 3)
Mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 8：1, GSH and the material of sodium selenite solution
Amount is than being 3:1；
（3）Magnetic agitation is carried out using 7T magnetic force, L-type ascorbic acid, L-type ascorbic acid and selenous acid are added while stirring
The mass ratio of sodium solution is 1.5：1, mixing time is 3 hours, is carried out during stirring under 30 DEG C of temperature conditionss, and reduction is prepared
Selenium solution containing zeroth order；
（4）The high-frequency resonance in quantum storehouse by 19T magnetic force of selenium solution containing zeroth order, the quantum selenium for preparing less than 70 hertz is molten
Liquid, resonance time is 60 seconds.
Embodiment 4
A kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the hydrogen selenite sodium solution that concentration is 1 × 10^ (- 3) mol/L is produced；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.4 ‰ in obtained sodium selenite solution are 8 × 10^ (- 3)
Mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 10：1, GSH and the material of sodium selenite solution
Amount is than being 4:1；
（3）Magnetic agitation is carried out using 5T magnetic force, L-type ascorbic acid, L-type ascorbic acid and selenous acid are added while stirring
The mass ratio of sodium solution is 2：1, mixing time is 8 hours, is carried out during stirring under 25 DEG C of temperature conditionss, and reduction, which is prepared, to be contained
Zeroth order selenium solution；
（4）The high-frequency resonance in quantum storehouse by 13T magnetic force of selenium solution containing zeroth order, the quantum selenium for preparing less than 70 hertz is molten
Liquid, resonance time is 90 seconds.
Embodiment 5
A kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the hydrogen selenite sodium solution that concentration is 1 × 10^ (- 3) mol/L is produced；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.4 ‰ in obtained sodium selenite solution are 8 × 10^ (- 3)
Mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 10：1, GSH and the material of sodium selenite solution
Amount is than being 4:1；
（3）Magnetic agitation is carried out using 7T magnetic force, L-type ascorbic acid, L-type ascorbic acid and selenous acid are added while stirring
The mass ratio of sodium solution is 2：1, mixing time is 3 hours, is carried out during stirring under 25 DEG C of temperature conditionss, and reduction, which is prepared, to be contained
Zeroth order selenium solution；
（4）The high-frequency resonance in quantum storehouse by 19T magnetic force of selenium solution containing zeroth order, the quantum selenium for preparing less than 70 hertz is molten
Liquid, resonance time is 60 seconds.
Claims (9)
1. a kind of preparation method of quantum selenium solution, it comprises the following steps：
（1）Using hydrogen selenite as selenium source, the selenous acid that concentration is 0.8 × 10^ (- 3) mol/L-1.2 × 10^ (- 3) mol/L is produced
Hydrogen sodium solution；
（2）The chitosan oligosaccharide solution and concentration that addition concentration is 0.3 ‰ -0.5 ‰ in obtained sodium selenite solution are 7.8 × 10
^ (- 3) mol/L-8.2 × 10^ (- 3) mol/L GSH, the wherein mass ratio of chitosan oligosaccharide solution and sodium selenite solution are 8-12：
1, GSH and sodium selenite solution amount of substance ratio be 3-5:1；
（3）Using 2.4T-7T magnetic force carry out magnetic agitation, while stirring add L-type ascorbic acid, L-type ascorbic acid with
The mass ratio of sodium selenite solution is 1.5-2.5：1, mixing time is 3-15 hours, in 20 DEG C -30 DEG C of temperature strip during stirring
Carried out under part, selenium solution containing zeroth order is prepared in reduction；
（4）The high-frequency resonance in quantum storehouse by 7T-19T magnetic force of selenium solution containing zeroth order, prepares the quantum of less than 70 hertz
Selenium solution, resonance time is 60-120 seconds.
2. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described sodium hydrogen selenite is molten
The concentration of liquid is 1 × 10^ (- 3) mol/L.
3. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described chitosan oligosaccharide solution
Concentration is 0.4 ‰.
4. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described GSH concentration is 8
×10^(-3)mol/L。
5. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described chitosan oligosaccharide solution with
The mass ratio of sodium selenite solution is 10：1.
6. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described GSH and selenous acid
The amount of substance ratio of sodium solution is 4:1.
7. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Described L-type ascorbic acid
Mass ratio with sodium selenite solution is 2：1.
8. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Used in described step three
7T magnetic force carries out magnetic agitation, and mixing time is 3 hours, and temperature during stirring is 25 DEG C.
9. a kind of preparation method of quantum selenium solution according to claim 1, it is characterized in that：Contain zero in described step four
Valency selenium solution high-frequency resonance in quantum storehouse by 19T magnetic force, resonance time is 60 seconds.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109757644A (en) * | 2019-03-11 | 2019-05-17 | 廖成蓉 | A kind of auxiliary decomposes the method, device and equipment of water dissolved matter |
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2017
- 2017-06-09 CN CN201710432166.4A patent/CN107224442A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1415310A (en) * | 2002-11-18 | 2003-05-07 | 安徽大学 | Nano selenium of chitin and its preparation method |
| CN103876159A (en) * | 2013-11-18 | 2014-06-25 | 国家海洋局第三海洋研究所 | Embedded nano elemental selenium composition and preparation method thereof |
| CN103876158A (en) * | 2013-11-18 | 2014-06-25 | 国家海洋局第三海洋研究所 | Elemental selenium and sugar compound and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109757644A (en) * | 2019-03-11 | 2019-05-17 | 廖成蓉 | A kind of auxiliary decomposes the method, device and equipment of water dissolved matter |
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