CN107213169A - A kind of external plaster for treating asthma - Google Patents
A kind of external plaster for treating asthma Download PDFInfo
- Publication number
- CN107213169A CN107213169A CN201710419653.7A CN201710419653A CN107213169A CN 107213169 A CN107213169 A CN 107213169A CN 201710419653 A CN201710419653 A CN 201710419653A CN 107213169 A CN107213169 A CN 107213169A
- Authority
- CN
- China
- Prior art keywords
- parts
- asthma
- plaster
- external plaster
- treating asthma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/28—Mercury; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Insects & Arthropods (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of external plaster for treating asthma, it is characterised in that is made up of the Chinese medicine of following parts by weight：10-50 parts of borneol, 50-100 parts of calcined and quenched CALAMINA, 50-100 parts of keel, 5-20 parts of insect wax, 50-100 parts of calcined gypsum, 50-100 parts of calomel mercurous chloride, 50-100 parts of rouge and powder, 50-100 parts of yellow lead.The present invention uses inner disease outer treat, good to the treatment clinical efficacy of asthma, safe.
Description
Technical field
The invention belongs to field of pharmaceutical preparations, and in particular to a kind of external plaster for treating asthma.
Background technology
Asthma is a kind of different substantiality disease being characterized with chronic airway inflammation, clinical manifestation mainly to cough, it is uncomfortable in chest, exhale
Inhale based on difficulty.Asthma prevalence is very high in world wide, especially in recent years due to the decline of environmental quality, asthma prevalence
Also constantly rising, according to statistics, the current world at least 300,000,000 asthmatic patients there are about 300,000 people to die from asthma every year.Asthma is not
The respiratory function of patient is only influenceed, as disease progression there is also a series of complication, such as bronchial infection, severe pneumonia
Deng.
Doctor trained in Western medicine is main by the method such as oxygen uptake, anti-inflammatory, anti-infective, calm, respiratory tract humidifying in treatment asthma, wherein,
Glucocorticoid (such as Budinad fog preparation) suction be treatment in it is most common be also the preferable method of most basic and clinical effectiveness
One of, and it is well known that hormone medicine, which is used for a long time, easily occurs a variety of topically or systemically adverse reactions.
Asthma is concluded into the category of " roar and demonstrate,prove " in theory of traditional Chinese medical science, it is believed that by the turbid obstructing airway of phlegm, lung qi lifting is unfavorable
Cause, in case of direct stimulation, chill invasion and attack etc. can induce this disease.More research all refers to cure in Chinese medicine in clinic,
But the research about external therapy of Chinese herb is seldom.
Because the absorption of externally applied drug, metabolic pathway are entirely different with oral medicine, it is that percutaneous osmosis is arrived
Up to internal body, the degraded of the first pass effect and medicine of liver in intestines and stomach can be avoided, the individual difference of medication can be reduced,
Blood concentration peak valley phenomenon caused by also avoid oral administration etc. simultaneously, reduces toxicity.
The A of CN 105853463 disclose a kind of Chinese medicine preparation treated ulcerative carbuncle ulcer, promote muscle growth, by borneol, forge
Calamine, calcined Dragon's bone, insect wax, calcined gypsum, calomel mercurous chloride, rouge and powder, the taste Chinese medicine material of yellow lead eight is made, but does not disclose treatment and roar
The purposes breathed heavily.
The content of the invention
The purpose of the present invention is there is provided a kind of external plaster for treating asthma, to improve for defect of the prior art
The curative effect for the treatment of asthma simultaneously reduces side effect.
The external plaster that the present invention is provided is made up of the Chinese medicine of following parts by weight：
Preferably, the parts by weight of each Chinese medicine are：
For in theory, above-mentioned Chinese medicine can be made the external plaster of any suitable Clinical practice, such as rubber paste,
Black plaster, gel emplastrum (i.e. Babu cream), ointment etc., currently preferred formulation is rubber paste and black plaster, both formulations
With curative effect more more preferable than other emplastrums, the overall clinical efficacy rate of asthma is treated up to more than 90%, and efficiency time is longer, it is secondary
Effect is less, does not find the adverse reactions such as 1 fash in clinical test.
It is further preferred that the external plaster is acupoint plaster, fei shu is sticked on when using, Hsinshu (acupoint), ke shu, fixed
Breathe heavily, the acupuncture point such as Danzhong, can faster, preferably play curative effect.
Embodiment
The present invention is described in detail below by embodiment.
Embodiment 1 treats the rubber paste of asthma
Borneol 30g, calcined and quenched CALAMINA 72g, keel 72g, insect wax 15g, calcined gypsum 72g, calomel mercurous chloride 72g, rouge and powder 72g, yellow lead
72g, common 477g.
(1) pretreatment of raw material：Above medicine is ground into fine powder, 150 mesh sieves are crossed；
(2) matrix is prepared：Raw rubber 2000g is taken, cleans, is cut into stick, being plasticated in rubber mixing machine reticulates thin slice, spreads out
Let cool, eliminate after electrostatic, be dipped in 6000g gasoline and soak 24 hours, beat in cream machine, stir after being moved into after complete swelling gel
Mix after 3-4 hours, vaseline 150g, lanolin 250g, zinc oxide 1600g, rosin 2500g are added by several times, matrix is made；
(3) creme is prepared：Fine drug powder is added into matrix, continues to stir into uniform rubber cement, after being filtered through rubber strainer
To creme.
(4) rubber paste is prepared：Creme is placed on plaster coating machine and applies cream, the adhesive plaster of creme is coated with, by heat drying and
Solvent recovery, is rolled up on roller, lined, cutting, packaging are produced.
The black plaster of embodiment 2
Borneol 15g, calcined and quenched CALAMINA 80g, keel 50g, insect wax 10g, calcined gypsum 50g, calomel mercurous chloride 50g, rouge and powder 50g, yellow lead
50g, common 355g.
1) raw material in addition to borneol is ground into fine powder together and mixed, borneol is individually ground into fine powder；
2) sesame oil 500g is taken, is poured into pot, 300-320 DEG C is heated to, by red lead 250g tripping in oil cauldrons, stirred and evenly mixed,
When being cooled to 270 DEG C, the raw material fine powder in addition to borneol is added, continues to stir into cream, stirring will be stirred along same direction
Mixing dynamics should be uniform long, until it is obtained plaster substantially uniformity, pitch-black shinny, then plaster is poured into cold water and soaked 3 days
To remove fiery poison, borneol fine powder is added after taking-up, finally plaster is shared in framed back material, produced.
The evaluation of clinical curative effect of embodiment 3
Choose 60 asthmatic patients that hospital accepts for medical treatment.Man 34, female 26 is 6~32 years old age, average 12.8 years old；At random
It is divided into control group and observation group, each 30.Control group man 19, female 11, observation group man 15, female 15, all patient's symbols
The Diagnosing Asthma standard that Chinese Medical Association formulates is closed, and without the organ dysfunction disease such as the serious heart, kidney, liver.Two groups of patient's bodies
The general information comparing difference such as weight, age is not statistically significant, with comparativity.
Control group gives simple western medicine and carries out clinical treatment, after infant is made a definite diagnosis, row oxygen uptake, it is anti-infective, calm, change
The western medicine routine treatments such as kind pulmonary microcirculation.Medicine is based on Budinad fog preparation, and treatment method is treated for suction-type,
Inhalation dose is 250 μ g/ times, 2-3 times/d.
External plaster of the present invention treatment is given by observation group, take borneol 30g, calcined and quenched CALAMINA 72g, keel 72g, insect wax 15g,
Calcined gypsum 72g, calomel mercurous chloride 72g, rouge and powder 72g, yellow lead 72g, are ground into fine powder, are mixed well with vaseline, be pasted on patient back fei shu,
6 acupuncture points such as Hsinshu (acupoint), ke shu, Dingchuan, Danzhong, then with immobilization with adhesive tape, are sticked once daily, every time patch 4-6 hours.
The standard of curative effect evaluation：It is effective：Patient's cough, SOA disappear, and spirit, appetite recover normal；Effectively：Patient
Cough, SOA mitigate, and spirit, appetite have a certain degree of recovery；It is invalid：Patient clinical sign is without improvement, or even adds
Weight.Total effective rate=(effective+effectively)/total cases × 100%.1 is the results are shown in Table after treatment.
The therapeutic effect of 1 two groups of patients of table compares
| Group | It is effective | Effectively | It is invalid | Total effective rate (%) |
| Observation group | 9 | 16 | 5 | 83.3% |
| Control group | 12 | 11 | 7 | 76.7% |
As can be seen from the above results, 83.3% has been reached using the overall clinical efficacy rate of drug therapy asthma of the present invention,
Higher than control group.Only have 1 in therapeutic process and occur slight allergic rash, and there are 3 generation allergic rash, 2 in observation group
Tachycardia occurs for example, and clinical efficacy and safety of the invention are superior to observation group.
Claims (4)
1. a kind of external plaster for treating asthma, it is characterised in that be made up of the Chinese medicine of following parts by weight：
2. the external plaster of asthma is treated as claimed in claim 1, it is characterised in that be made up of the Chinese medicine of following parts by weight：
3. the external plaster of asthma is treated as claimed in claim 1 or 2, it is characterised in that：The external plaster be rubber paste or
Black plaster.
4. the external plaster of asthma is treated as claimed in claim 3, it is characterised in that：The external plaster is acupoint plaster.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710419653.7A CN107213169B (en) | 2017-06-06 | 2017-06-06 | External plaster for treating asthma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710419653.7A CN107213169B (en) | 2017-06-06 | 2017-06-06 | External plaster for treating asthma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107213169A true CN107213169A (en) | 2017-09-29 |
| CN107213169B CN107213169B (en) | 2020-04-28 |
Family
ID=59947478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710419653.7A Active CN107213169B (en) | 2017-06-06 | 2017-06-06 | External plaster for treating asthma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107213169B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1141796A (en) * | 1996-01-12 | 1997-02-05 | 黄德轩 | Plaster for treatment of bronchial asthma |
| CN1565578A (en) * | 2003-06-11 | 2005-01-19 | 董保民 | Medicinal pills for treating enfant asthma |
| CN104398777A (en) * | 2014-12-01 | 2015-03-11 | 羊元庆 | Traditional Chinese medicament for treating bronchial asthma |
| CN105327147A (en) * | 2015-12-04 | 2016-02-17 | 山东新希望六和集团有限公司 | Medicine composition for treating swine enzootic pneumonia and preparation method thereof |
| CN105853463A (en) * | 2016-05-17 | 2016-08-17 | 健民集团叶开泰国药（随州）有限公司 | Traditional Chinese medicinal preparation for treating carbuncle ulcer and promoting muscle growth as well as preparing method and application thereof |
-
2017
- 2017-06-06 CN CN201710419653.7A patent/CN107213169B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1141796A (en) * | 1996-01-12 | 1997-02-05 | 黄德轩 | Plaster for treatment of bronchial asthma |
| CN1565578A (en) * | 2003-06-11 | 2005-01-19 | 董保民 | Medicinal pills for treating enfant asthma |
| CN104398777A (en) * | 2014-12-01 | 2015-03-11 | 羊元庆 | Traditional Chinese medicament for treating bronchial asthma |
| CN105327147A (en) * | 2015-12-04 | 2016-02-17 | 山东新希望六和集团有限公司 | Medicine composition for treating swine enzootic pneumonia and preparation method thereof |
| CN105853463A (en) * | 2016-05-17 | 2016-08-17 | 健民集团叶开泰国药（随州）有限公司 | Traditional Chinese medicinal preparation for treating carbuncle ulcer and promoting muscle growth as well as preparing method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 何强等: "三九贴穴位贴敷对哮喘大鼠血清IgE含量影响的研究", 《新疆医科大学学报》 * |
| 朱初荣: "护理干预在冬病夏治穴位敷贴治疗哮喘的临床护理效果", 《中外女性健康研究》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107213169B (en) | 2020-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102772591B (en) | Hollow, ventilation and double-layer traditional Chinese medicine suppository for treating rhinitis and production method of traditional Chinese medicine suppository | |
| CN104306793B (en) | A kind of Chinese medicine preparation for treating lobar pneumonia | |
| CN104225126B (en) | A kind of preventing phlegm from forming and stopping coughing patch | |
| CN107213169A (en) | A kind of external plaster for treating asthma | |
| CN104147261B (en) | A kind of Chinese medicine preparation for treating rheumatic arthritis | |
| CN113230374A (en) | External formula for treating cold in uterus and preparation method and application thereof | |
| CN106492186B (en) | A kind of drug for treating acute and chronic tracheobronchitis | |
| CN105853463A (en) | Traditional Chinese medicinal preparation for treating carbuncle ulcer and promoting muscle growth as well as preparing method and application thereof | |
| CN101297954B (en) | Unbilical medicament for treating cough and preparation thereof | |
| CN104815029B (en) | A kind of drug and preparation method thereof for treating tinea pedis | |
| CN108126008A (en) | Rosemary cordyceps sinensis ball | |
| CN109512874B (en) | Massage emulsion for treating infantile exogenous fever and preparation method thereof | |
| CN107375422A (en) | Treatment part catarrh symptom liniment and preparation method thereof | |
| CN115531503A (en) | External traditional Chinese medicine composition for rehabilitation period of novel coronavirus pneumonia, acupoint plaster, preparation method and application | |
| CN108236623B (en) | Pharmaceutical composition, traditional Chinese medicine oral liquid, traditional Chinese medicine granules and preparation method and application thereof | |
| CN106729939A (en) | A kind of dressing for treating bedsore | |
| JPS5813518A (en) | Preparation of drug consisting of ganoderma lucidum and elfvingia applanata | |
| CN109876091A (en) | The Chinese medicine composition and preparation method for treating biliary tract tying stone and calculi in urinary system | |
| CN109846861A (en) | A kind of anaesthetic external plaster and preparation method thereof | |
| CN104189076A (en) | Traditional Chinese medicine patch for treating juvenile bronchial asthma and preparation method thereof | |
| CN113662980A (en) | Health foot bath composition | |
| CN104784454A (en) | Traditional Chinese medicine for treating hyperthyroidism | |
| CN114470091A (en) | Health-care plaster for treating heat cough | |
| CN108159219A (en) | A kind of Chinese medicine for treating asthma in children | |
| CN103989856A (en) | Traditional Chinese medicine for treating tinea pedis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |