CN107198666B - 一种含有岗松提取物的止痒露及其生产方法 - Google Patents
一种含有岗松提取物的止痒露及其生产方法 Download PDFInfo
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Abstract
本发明涉及一种含有岗松提取物的止痒露及其生产方法，各组分及各组分的重量百分比为：岗松油1‑10%、桉油1‑10%、薄荷油1‑5%、冰片0.1‑1%、聚山梨酯80 1‑10%和纯化水补足100%。该止痒露温和无刺激性，适宜婴幼儿童及成人使用。对蚊虫叮咬有非常好的止痒效果，叮胞也会消除，具有止痒、消炎、杀菌的功效。有预防因蚊虫叮咬感染病毒的作用。
Description
技术领域
本发明涉及日化领域，具体是一种含有岗松提取物的止痒露及其生产方法。
背景技术
随着社会发展，人们对生活用品的健康需求越来越高，夏日炎炎，蚊虫躁动，经常骚扰人类的居住环境。目前，使用止痒露防治蚊虫叮咬已经普遍被人们接受，止痒露有提神，驱蚊，止痒等作用。而目前防治蚊虫叮咬的止痒露中有效成分大多为化学成分如驱蚊酯等化学农药，长期使用或使用不当易对人们身体造成危害。而以植物源物质为主要组分的止痒露，由于安全无公害逐渐受到人们的喜爱。多种植物曾被用于止痒露的成分，如薰衣草、艾叶、野菊花和丁香等。而岗松由于具有祛风行气，利水通淋，解毒止痒的功效，也被人们作为止痒的成分进行了研究。如：
1申请号为CN105943418A的发明：一种消肿止痒的茶树复方精油，其所用原料按重量份计包括：茶树精油15份、薄荷精油10份、竹鼠油5份、岗松精油5份、万寿菊精油5份、天竺葵精油3份、橙花精油1份。
2.申请号为CN104510687A的发明：一种中药止痒沐浴露，包括皂角35-50份、洗米水提取液12-18份、岗松8-17份、檀香木提取液8-12份、苦楝皮5-9份、龙须草4-12份、茴香3-8份、朴硝4-10份、盐蛇粉4-12份和二叶律2-6份。
3.申请号为CN104546625A的发明：一种中草药护肤止痒沐浴露，由以下重量份数的原料制成：茉莉花35-50份、艾叶12-18份、岗松8-17 份、川乌8-12份、苦楝皮5-9份、龙须草4-12份、茴香3-8份、朴硝4-10份、盐蛇粉 4-12份和二叶律2-6份。
综上，虽然人们已经对岗松与多种植物成分配伍，作为止痒成分进行了相关研究，但并没有将岗松油、桉油、薄荷油和冰片共同使用作为止痒露成分的研究报道。
发明内容
本发明针对现有技术的上述不足，提供一种含有岗松提取物的止痒露及其生产方法，该止痒露驱蚊效止痒果佳，对人体无任何毒副作用。
本发明的技术方案是这样实现的：
本发明的含有岗松提取物的止痒露，各组分及各组分的重量百分比为：
岗松油1.0～10.0% 、桉油1.0～10.0%、薄荷油1.0～5.0%、冰片0.1～1.0%、聚山梨酯-80 1.0～10.0%、乙醇1.0～10.0%和纯化水补足100%。
优选的，所述止痒露各组分及各组分的重量百分比为：岗松油3.0～8.0% 、桉油1.0～5.0%、薄荷油3.0～5.0%、冰片0.2～0.5%、聚山梨酯-80 5.0～8.0%、乙醇1.0～10.0%和纯化水补足100%。
本发明岗松油和桉油作为止痒露的主要活性成分，并对这两种植物油对蚊子成虫熏蒸的联合毒力进行了测定，发现二者合用具有很好的增效作用。
本发明上述中药成分的功效为：
岗松油为桃金娘科岗松属植物岗松Baeckea frutescens L.带有花果的枝叶经水蒸气蒸馏得到的挥发油，为淡黄色至淡棕黄色的澄清液体，气芳香，具有特殊的香味，岗松主要分布于广西、广东、江西、福建等地，具有化瘀止痛、清热解毒、利尿通淋、杀虫止痒之功效。岗松油作为广西地方习用中药材收载于《广西中药材标准》，具有清热利湿、杀虫止痒之功效。用于皮肤湿疹、瘙痒、淋病、疥疮、滴虫性阴道炎、脚藓。
桉油为桃金娘科植物蓝桉 Eucalyptus globulus Labill.、樟科植物樟Cinnamomum camphora (L.) Sieb. 或上述两科同属其他植物经水蒸气蒸镏得到的挥发油。为无色或微黄色的澄清液体，有特异的芳香气，微似樟脑，味辛、凉。具有祛风止痛之功效，用于皮肤瘙痒，神经痛。
薄荷油，疏风，清热；治外感风热，头痛目赤，咽痛，齿痛，皮肤风痒。
冰片，通诸窍，散郁火，去翳明目，消肿止痛。治中风口噤，热病神昏，惊痫痰迷，气闭耳聋，喉痹，口疮，中耳炎，痈肿，痔疮，目亦翳膜，蛲虫病。
本发明含有岗松提取物的止痒露的生产方法，其步骤如下：
（1）按比例往反应釜中加入岗松油、桉油、薄荷油和聚山梨酯-80，开启搅拌，搅拌10～15min。
（2）在溶解釜中加入冰片和乙醇，搅拌溶解至透明。
（3）将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min，即得半成品。
（4）检测、分装得成品。
所述反应釜的搅拌速度为125～225r/min；搅拌温度为10-22℃。
发明人将岗松油和桉油按照不同比例复配，发现其驱蚊效果极佳，有明显的增效作用，同时毒副作用小，对婴儿、孕妇及老人均不会产生不良反应。
本发明的有益效果是：
本发明含有岗松提取物的止痒露，以中药科学理论为基础，利用中药的互相协同作用选择岗松精油、大叶桉油和薄荷油为原料，生产的止痒露具有很好的驱蚊止痒效果，对蚊虫叮咬后的叮胞也有良好的治疗作用。经本发明人反复验证，对皮肤及呼吸道没有不良影响，长期使用本产品，对人体无任何毒副作用。
具体实施方式
实施例1
取岗松油10kg、桉油10kg、薄荷油10kg、聚山梨酯-80 10kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入1kg冰片和乙醇10kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min；控制搅拌速度为125/min；搅拌温度为10℃，即得。
实施例2
取岗松油100kg、桉油100kg、薄荷油50kg、聚山梨酯-80 100kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入10kg冰片和乙醇100kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入纯净水补足1000kg，开启搅拌10～15min；控制搅拌速度为225/min；搅拌温度为22℃，即得。
实施例3
取岗松油30kg、桉油10kg、薄荷油30kg、聚山梨酯-80 50kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入2kg冰片和乙醇50kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min；控制搅拌速度为150/min；搅拌温度为20℃，即得。
实施例4
取岗松油80kg、桉油50kg、薄荷油50kg、聚山梨酯-80 80kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入5kg冰片和乙醇80kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min；控制搅拌速度为225/min；搅拌温度为20℃，即得。
实施例5
取岗松油60kg、桉油60kg、薄荷油50kg、聚山梨酯-80 80kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入2kg冰片和乙醇50kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min；控制搅拌速度为225/min；搅拌温度为20℃，即得。
实施例6
取岗松油40kg、桉油50kg、薄荷油50kg、聚山梨酯-80 80kg加入反应釜中，开启搅拌，搅拌10～15min；然后在溶解釜中加入4kg冰片和乙醇70kg，搅拌溶解至透明；将溶解好的冰片加入反应釜，加入余量纯净水，开启搅拌10～15min；控制搅拌速度为225/min；搅拌温度为20℃，即得。
实验实施例 7
岗松油及大叶桉油对蚊子成虫联合毒力的测定
采用三角瓶密闭熏蒸法，测定岗松油和大叶桉油对淡色库蚊的熏蒸致死活性，具体方法为：
在三角瓶 (V=330mL) 中接入20 头健康的淡色库蚊雌虫。同时将一条长 3cm宽1cm的滤纸条的一端用大头针固定在橡皮塞上，用微量进样器在滤纸上加入用丙酮稀释成不同梯度浓度的供试样品。样品加入后迅速塞紧橡皮塞，在温度26℃ ±1℃，相对湿度 65%±5% 条件下处理，5h 后检查蚊虫死亡结果。以用镊子尖部刺激蚊虫腹部，蚊虫没有反应为死亡标准。每处理重复 3 次，设空白对照。供试样品如下：
| 编号 | 供试样品 |
| 1 | 岗松油 |
| 2 | 大叶桉油 |
| 3 | 岗松油：大叶桉油=1:1 |
| 4 | 岗松油：大叶桉油=1:10 |
| 5 | 岗松油：大叶桉油=1:5 |
| 6 | 岗松油：大叶桉油=1:3 |
| 7 | 岗松油：大叶桉油=3:1 |
| 8 | 岗松油：大叶桉油=5:1 |
| 9 | 岗松油：大叶桉油=10:1 |
| 10 | 薄荷油 |
| 11 | 空白对照 |
结果如表 1 所示。
可以看出，以岗松油和大叶桉油为主要驱蚊成分，两者复配具有明显的增效作用，共毒系数大于200。
发明人发明的以上含有岗松提取物为成分的止痒露，对蚊子叮咬过的叮胞也有良好的治愈作用，其特性为：温和无刺激性，适宜婴幼儿童及成人使用，具有止痒、消炎、杀菌的功效。有预防因蚊虫叮咬感染病毒的作用。
Claims (2)
1.一种含有岗松提取物的止痒露，其特征在于：所述止痒露各组分及各组分的重量百分比为：岗松油1.0～10.0% 、桉油1.0～10.0%、薄荷油1.0～5.0%、冰片0.1～1.0%、聚山梨酯-80 1.0～10.0%、乙醇1.0～10.0%和纯化水补足100%；
所述含有岗松提取物的止痒露的生产方法，包括如下步骤：
（1）按比例往反应釜中加入岗松油、桉油、薄荷油和聚山梨酯-80，开启搅拌，搅拌10～15min；所述反应釜的搅拌速度为125～225r/min；搅拌温度为10-22℃；
（2）在溶解釜中加入冰片和乙醇，搅拌溶解至透明；
（3）将溶解好的冰片加入反应釜，加入纯净水至规定量，开启搅拌10～15min，即得半成品；
（4）检测、分装得成品。
2.根据权利要求1所述的含有岗松提取物的止痒露，其特征在于：所述止痒露各组分及各组分的重量百分比为：岗松油3.0～8.0% 、桉油1.0～5.0%、薄荷油3.0～5.0%、冰片0.2～0.5%、聚山梨酯-80 5.0～8.0%、乙醇1.0～10.0%和纯化水补足100%。
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