CN107184418A - 一种含普鲁兰多糖的护发素 - Google Patents

一种含普鲁兰多糖的护发素 Download PDF

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CN107184418A
CN107184418A CN201710219124.2A CN201710219124A CN107184418A CN 107184418 A CN107184418 A CN 107184418A CN 201710219124 A CN201710219124 A CN 201710219124A CN 107184418 A CN107184418 A CN 107184418A
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conditioner
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pulullan polysaccharide
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刘少英
孟祥璟
赵文刚
朱希强
凌沛学
杨素珍
边玲
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Shandong Freda Pharmaceutical Group Co ltd
Shandong Academy of Pharmaceutical Sciences
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Shandong Academy of Pharmaceutical Sciences
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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Abstract

本发明公开一种含有普鲁兰多糖的护发素,属于化妆品领域。包括以下重量份数原料:普鲁兰多糖0.1~10份、阳离子调理剂2~20份、增稠剂0.1~15份、去屑剂0.2~1.0份、防腐剂0.2~1.0份,去离子水加至100份。本发明的含有普鲁兰多糖的护发素,各种原料相互协调,修护头发干枯、开叉、易断及其他受损发质,有效保护头发,并能滋养头皮,令秀发更柔、更顺、更亮泽。

Description

一种含普鲁兰多糖的护发素
技术领域
本发明属于化妆品领域,具体涉及一种含有普鲁兰多糖的护发素。
背景技术
毛发最外层结构为毛表皮,由扁平的角质细胞构成,角质细胞交错重叠呈鱼鳞片状,也称毛鳞片。健康头发的毛鳞片排列整齐,光滑,表面覆盖皮脂,头发柔顺亮泽、易于梳理。毛表皮是头发的保护层,抵御外来刺激,保护皮脂,抑制水分蒸发散失。通常的染发、烫发、强紫外照射等均会对毛鳞片造成损害。毛鳞片翘起、损伤,头发会失去光泽,手感粗糙,毛发之间摩擦力增加,又加剧了头发损伤。毛鳞片损伤、脱落,减弱了对头发内部结构的保护作用,导致头发失水干枯、韧性降低,容易断裂。常规护发素中包含几类护发原料:(1)阳离子调理剂,常用聚氨基阳离子化合物,带大量正电荷,可中和天然头发的负电性,降低静电,改善头发的梳理性。(2)硅油,具有黏附性和延展性,结合在头发表面和毛鳞片空隙中,使头发柔顺光滑、易于梳理。(3)保湿剂,减缓头发的水分散失,维护头发健康,增强头发弹性。但长期使用含硅油的护发素,硅油残留对人类健康的负面影响已经引起广泛讨论,可能在头皮上堵塞毛囊、引发过敏。
普鲁兰多糖(pullulan),中文译为普鲁兰,也叫普鲁兰糖、茁霉多糖、普聚多糖,在《已使用化妆品原料名称目录》中,称为出芽短梗酶多糖。是由葡萄糖残基组成的直链状同型多聚糖,葡萄糖以α-1,4-糖苷键连接成麦芽三糖,麦芽三糖由α-(1→6)糖苷键连接形成高分子的普鲁兰多糖,纯品是无味无嗅的白色粉末。普鲁兰多糖是一种安全无毒害的天然多糖,具有水溶性、可食用性、成膜性,阻气性,因此在医药、食品、化妆品、农药等行业具有广泛的用途。
发明内容
本发明提供一种含普鲁兰多糖的护发素,以解决头发受损后粗糙、干枯的问题,并能滋润头皮,提高头皮和头发的自我保护能力。
本发明采取的技术方案如下。
一种含普鲁兰多糖的护发素,护发素配方组分含有普鲁兰多糖、阳离子调理剂、增稠剂、去屑剂和防腐剂和去离子水。
所述各组分按重量计为:
所述的普鲁兰多糖平均分子量为1×105~1×107
所述的阳离子调理剂为十六烷基三甲基氯化铵、十二烷基三甲基氯化铵、十二烷基二甲基苄基氯化铵、十八烷基二甲基苄基氯化铵、双十二烷基二甲基氯化铵、聚季铵盐中的一种或多种混合。
所述的增稠剂为甘油、丙二醇、聚乙二醇、山梨醇中的一种或多种混合。
所述的去屑剂为吡啶硫酸铜锌、二唑酮中的一种或两种混合。
所属的防腐剂为羟苯甲酯、羟苯丙酯、氯苯甘醚、苯氧乙醇中的一种或多种混合。
制备时,计算各原料的用量,在制备罐中加入离子水,开启搅拌,然后加入普鲁兰多糖、阳离子调理剂、增稠剂、防腐剂,搅拌30min使各物料充分溶解即可得成品。
本发明护发素中各成分的主要作用如下:
1、普鲁兰多糖具有优良护发性能。首先,其水溶液铺展在头发表面和毛鳞片空隙中,当头发干燥时,毛鳞片空隙中的普鲁兰多糖发挥胶黏剂作用,使毛鳞片与头发内部结构紧密贴合,减少因毛鳞片翘起而造成的粗糙和失水干枯。其次,头发表面的普鲁兰多糖发挥类似硅油的作用,形成一层保护膜,使头发光亮、光滑、易于梳理,但避免了硅油长期使用对头皮造成的损伤。再次,普鲁兰多糖是一种天然的保湿剂,减缓头发水分散失。此外,普鲁兰糖的保湿性能使其对头皮也有保护作用,促进头皮健康,进而从根本上提高头发的健康状况。
2、阳离子调理剂具有中和头发表面负电荷的作用,减少头发所带静电,使头发柔软,易于梳理。
3、增稠剂辅助普鲁兰多糖,调节护发素的黏稠程度和保湿性能。
4、去屑剂杀菌、抗霉,抑制头皮屑的产生。
与现有技术相比,本发明护发素产生以下有益效果:
1、既可修护受损头发,又可滋润头皮,抑制头屑产生,从根本上改善头发健康状况。
2、配方中无油脂成分,使用感觉清爽不油腻。
3、不含硅油,长期使用无副作用。
4、在常温状态下,用冷水即可配置完成,简化生产工艺,减少能源消耗。
具体实施方式
为了更好地理解本发明,下面结合实施例子对本发明作进一步描述,但本发明所保护范围不仅限于此。
实施例1
在制备罐中首先加入67.9kg去离子水,开启搅拌,然后加入10.0kg普鲁兰多糖,20.0kg十二烷基二甲基苄基氯化铵,0.1kg丙二醇,0.5kg二唑酮,0.5kg吡啶硫酸铜锌,0.2kg羟苯甲酯、0.3kg羟苯丙酯、0.2kg氯苯甘醚、0.3kg苯氧乙醇,搅拌30min使各物料充分溶解即可得成品。
实施例2
在制备罐中首先加入68.0kg去离子水,开启搅拌,然后加入0.1kg普鲁兰多糖,2.0kg十二烷基二甲基苄基氯化铵,5.0kg聚乙二醇,10.0kg甘油,0.2kg二唑酮,0.1kg羟苯甲酯,0.1kg苯氧乙醇,搅拌30min使各物料充分溶解即可得成品。
实施例3
在制备罐中首先加入86.2kg去离子水,开启搅拌,然后加入8.0kg普鲁兰多糖,2.5kg十二烷基二甲基苄基氯化铵,2.0kg山梨醇,0.8kg吡啶硫酸铜锌,0.2kg氯苯甘醚,0.3kg羟苯丙酯,搅拌30min使各物料充分溶解即可得成品。
实施例4
在制备罐中首先加入79.0kg去离子水,开启搅拌,然后加入3.0kg普鲁兰多糖,5.0kg十六烷基三甲基氯化铵,12.0kg甘油,0.7kg吡啶硫酸酮锌,0.3kg苯氧乙醇,搅拌30min使各物料充分溶解即可得成品。
实施例5
在制备罐中首先加入68.85kg去离子水,开启搅拌,然后加入2.0kg普鲁兰多糖,5.0kg十二烷基三甲基氯化铵,10.5kg聚季铵盐,4.5kg丙二醇,8.0kg山梨醇,0.2kg吡啶硫酸酮锌,0.25kg二唑酮,0.2kg羟苯丙酯,0.2kg氯苯甘醚,0.3kg苯氧乙醇,搅拌30min使各物料充分溶解即可得成品。
实施例6
在制备罐中首先加入82.1kg去离子水,开启搅拌,然后加入0.8kg普鲁兰多糖,5.5kg十八烷基二甲基苄基氯化铵,2.5kg聚季铵盐,8.0kg聚乙二醇,0.2kg吡啶硫酸酮锌,0.2kg二唑酮,0.3kg羟苯甲酯,0.4kg氯苯甘醚,搅拌30min使各物料充分溶解即可得成品。
测试例
选取一种常见市售畅销护发素为对照样品,编号为C。实施例1~6的护发素样品编号为T1、T2、T3、T4、T5、T6。各样品分别用在因烫染而发质干枯粗糙的人群上(每样品试用人数均为30人)。使用方法为:洗发后,将受试护发素样品在头发与头皮上涂抹揉匀2min,清水冲洗2min,连续使用1个月,受试者根据试用感受对样品评分,满分为10。将每个指标的打分求取平均值,统计多项指标的平均打分情况,结果见表1。
表1美发室测试试验结果
由表1可见,相比市售产品,本发明生产的含普鲁兰多糖的护发素使头发更具亮泽,使用感觉更加清爽不油腻,还有显著的去屑止痒效果,修复发丝损伤,对头发和头皮的状况都有改善作用。
以上仅是本发明的优选实施方式,并不用于限制本发明,对于本领域的普通技术人员来说,本发明可以有各种变化和更改。凡在不脱离本发明原理的前提下,所做的修改、等同替换、改进、润饰等,均应包含在本发明的保护范围之内。

Claims (6)

1.一种含普鲁兰多糖的护发素,其特征在于,所述的护发素配方组分含有普鲁兰多糖、阳离子调理剂、增稠剂、去屑剂和防腐剂和去离子水;所述的各组分按重量计为:普鲁兰多糖0.1~10份、阳离子调理剂2~20份、增稠剂0.1~15份、去屑剂0.2~1.0份、防腐剂0.2~1.0份,去离子水加至100份。
2.如权利要求1所述的一种护发剂,其特征在于,所述的普鲁兰多糖平均分子量为1×105~1×107
3.如权利要求1所述的一种护发剂,其特征在于,所述的阳离子调理剂为十六烷基三甲基氯化铵、十二烷基三甲基氯化铵、十二烷基二甲基苄基氯化铵、十八烷基二甲基苄基氯化铵、双十二烷基二甲基氯化铵、聚季铵盐中的一种或多种混合。
4.如权利要求1所述的一种护发剂,其特征在于,所述的增稠剂为甘油、丙二醇、聚乙二醇、山梨醇中的一种或多种混合。
5.如权利要求1所述的一种护发剂,其特征在于,所述的去屑剂为吡啶硫酸铜锌、二唑酮中的一种或两种混合。
6.如权利要求1所述的一种护发剂,其特征在于,所属的防腐剂为羟苯甲酯、羟苯丙酯、氯苯甘醚、苯氧乙醇中的一种或多种混合。
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Application publication date: 20170922