CN107180167B - Checking method and device for hereditary disease gene diagnosis detection - Google Patents

Checking method and device for hereditary disease gene diagnosis detection Download PDF

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CN107180167B
CN107180167B CN201710371620.XA CN201710371620A CN107180167B CN 107180167 B CN107180167 B CN 107180167B CN 201710371620 A CN201710371620 A CN 201710371620A CN 107180167 B CN107180167 B CN 107180167B
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matching entries
project
pathological examination
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CN107180167A (en
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王家健
陶然
胡朝晖
王永松
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Hainan Jinyu Medical Testing Center Co Ltd
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Hainan Jinyu Medical Testing Center Co Ltd
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    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

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Abstract

Checking method disclosed by the invention for hereditary disease gene diagnosis detection is instructed according to the audit to pending project received, starts the detection system for judging the project and whether patient information meets preset audit condition;If meeting, it is determined that the seeking scope of the matching entries;If the seeking scope of the matching entries is only limitted to same bar code, the pathological examination of the matching entries is then searched in first database, if the seeking scope of matching entries is extended under different bar codes, first search the matching entries in first database under same bar code, when searching in first database less than matching entries under same bar code, begin looking for the matching entries in the second database under different bar codes, according to the contradiction condition of preset pending project and matching entries, obtain the auditing result of the pathological examination of the pending project, largely reduce the investment of manual analysis and comparison, reduce error rate, improve the efficiency of audit.

Description

Checking method and device for hereditary disease gene diagnosis detection
Technical field
The present invention relates to medical detection field more particularly to it is a kind of for hereditary disease gene diagnosis detection checking method and Device.
Background technique
Continuous with medical system perfects, and the inspection service as medical diagnosis on disease means is also more specialized and various Change.With the increase of the project of inspection, the increase of specimen amount, the sample turnaround time will extend according to original process, but above Clinical demand and laws and regulations requirement require laboratory to shorten the sample turnaround time as far as possible, how to divide without any confusion sample Class, rationally effective optimization laboratory testing process, the reasonable convenience of laboratory information system design become shortening sample The key link of turnaround time.The classification that independent laboratory carries out project at present is mainly divided: physical and chemical mass spectrum inspection, genome inspection Test, pathological diagnosis, biochemical luminous inspection, immunological test, other comprehensive tests etc., because detection project is more, in addition project push away it is old New fast out, the requirement to testing result auditor is also constantly promoted.
Exceptional sample, such as piarhemia, haemolysis, further includes the project that result needs artificial judgment to screen, this portion except sample is interfered The confirmation of point result needs to carry out artificial treatment, and such as centrifugation is surveyed again, push jack microscopy or connection are clinical.This part sample expends a large amount of Time can significantly postpone sending time of other reports;Simultaneously under the pressure of sample turnaround time, lab assistant can It can neglect or simplify due process flow, the risk of result is caused to be significantly increased.Nowadays, almost all of laboratory report List is accused by manually signing and issuing, it is about 1000 or more that one, which is signed and issued report personnel to sign and issue reporting quantities a working day, and And largely limitation is carried out to morning (21:00-04:00) at night for these work, the period prolonged computation is examined Nuclear Data is easy to cause the dual fatigue of vision and body and mind, leads to the generation of mistake;Meanwhile if the result of report is related to learning Comparison and analysis between section, it is also necessary to a large amount of craft historical record inquiry, the analysis work of entire data by it is for 6 hours with On.
Summary of the invention
The purpose of the embodiment of the present invention is that providing a kind of checking method and device for hereditary disease gene diagnosis detection, energy Logical contradiction between automatic early-warning pathological examination, the automatic reasonability for examining pathological examination, without artificial comparison and analysis.
To achieve the above object, the embodiment of the invention provides a kind of audit sides for hereditary disease gene diagnosis detection Method, comprising steps of
It receives the audit to the pathological examination of the pending project under any bar code to instruct, judges the pending project Whether detection system matches with preset detection system, and judges whether the patient information of the bar code limits with preset data System matches;
If the detection system of the pending project matches with preset detection system, and the patient information of the bar code Match with the limitation of preset data, it is determined that the seeking scope of preset matching entries;Wherein, the matching entries for institute State the preparatory associated project of pending project;
If the seeking scope of preset matching entries includes the matching entries under same bar code, but does not include under different bar codes Matching entries when, then M pathological examination of the matching entries is obtained according to first database;Wherein, M >=0;Wherein, institute State the testing result that first database includes several projects under the bar code;
If the seeking scope of preset matching entries includes the matching under matching entries and different bar codes under same bar code When project, then N number of testing result of the matching entries is obtained according to first database;Wherein, N >=0;
As N=0, then X testing result of the matching entries is obtained according to the second database;Wherein, X >=0;Its In, the second database includes the testing result of several projects under different bar codes;The occurrence obtained according to the second database Mesh need to meet preset condition, the preset condition be other bar codes where the matching entries patient information with it is described The patient information of bar code where pending project matches;
When M, which is greater than or equal to 1, N, is greater than or equal to 1 or X more than or equal to 1, according to the pending project and matching The contradiction condition of project judges the pathological examinations of the pending project and matching entries with the presence or absence of contradiction, obtain it is described to The auditing result of the pathological examination of audit project;Wherein, contradiction if it exists, the then audit of the pathological examination of the pending project As a result do not pass through for audit;Contradiction if it does not exist, then the auditing result of the pathological examination of the pending project is that audit passes through.
Compared with prior art, the checking method disclosed by the invention for hereditary disease gene diagnosis detection is according to receiving The audit of pending project is instructed, start the detection system for judging the project and whether patient information meet preset examine Core condition;If meeting, it is determined that the seeking scope of the matching entries;If the seeking scope of the matching entries is only limitted to same Bar code then searches the pathological examination of the matching entries in first database, if the seeking scope of matching entries is extended to not When under bar code, the matching entries in first database under same bar code are first searched, when searching in first database less than same When matching entries under bar code, the matching entries in the second database under different bar codes are begun looking for, according to preset pending The contradiction condition of project and matching entries obtains the auditing result of the pathological examination of the pending project, largely The investment of manual analysis and comparison is reduced, error rate is reduced, improves the efficiency of audit.
As an improvement of the above scheme, the pathological examination type of the pending project and matching entries include numeric type and Text-type.
As an improvement of the above scheme, the contradiction condition of the pending project and matching entries specifically:
The pathological examination of the pending project is that the pathological examination of ascendant trend and the matching entries is downward trend; Wherein, the ascendant trend is the upper limit threshold more than preset term of reference, and the downward trend is described lower than preset The lower threshold of term of reference;The pathological examination type of the pending project and matching entries is numeric type.
As an improvement of the above scheme, the contradiction condition of the pending project and matching entries are as follows:
The pathological examination of the pending project is less than preset numerical value and the pathological examination of matching entries and preset text This is consistent;Wherein, the pathological examination type of the matching entries is numeric type, and the pathological examination type of the matching entries is text This type.
As an improvement of the above scheme, the matching entries include first item and second item, the pending project With the contradiction condition of matching entries specifically:
The pathological examination of the pending project is less than the pathological examination and preset text of preset numerical value, first item Consistent and second item pathological examination is greater than preset numerical value;Wherein, the pathology of the pending project and second item Result type is numeric type, and the pathological examination type of the first item is text-type.Matching entries need according to have verified that with The internal association of pending project is preset, and ensure that the science and preciseness of audit.
As an improvement of the above scheme, it further comprises the steps of:
If X is equal to 0, judge whether the pathological examination of the pending project meets preset implied condition;
If the pathological examination of the pending project meets preset implied condition, alerting signal is issued;Wherein, described to mention Signal wake up for reminding the pathological examination for receiving the matching entries.
As an improvement of the above scheme, the patient information of the bar code matches with the limitation of preset data and specifically includes: The patient age of the bar code is in default range, the Gender of the bar code and preset gender limit consistent and institute It states the corresponding information for hospital of bar code and the limitation of preset hospital is one of consistent or a variety of.
As an improvement of the above scheme, it further comprises the steps of:
According to the auditing result of each pathological examination in the pending project, early warning is issued;Wherein, if it is described to It is at least obstructed out-of-date to audit in the presence of the early warning result of a pathological examination in audit project, issue the unacceptable prompt of early warning; If the auditing result of each pathological examination is that audit passes through in the pending project, the prompt that early warning passes through is issued;
According to the early warning of pending project each under the bar code as a result, issuing early warning;Wherein, if under the bar code It is at least that early warning is obstructed out-of-date in the presence of the early warning result of a pending project, issues the unacceptable prompt of early warning;If institute When the early warning result for stating each pending project under bar code is that early warning passes through, the prompt that early warning passes through is issued.
As an improvement of the above scheme, the pathological examination of the matching entries is obtained according to the second database specifically:
Other bar codes where the pathological examination of the matching entries are obtained according to second database;
It obtains other described bar codes and obtains corresponding patient information, by the patient information of other bar codes and the bar code Patient information be compared, matched when patient condition and the patient condition of the bar code of other bar codes meet hospital, When gender matching, name matches and the difference at age are less than preset threshold value, then the matching is obtained according to other described bar codes The pathological examination of project.Above-mentioned steps can matching entries under the same patient's difference bar code of quick obtaining, to judge first item Pathological examination it is whether reasonable.
The embodiment of the invention also provides a kind of audit devices for hereditary disease gene diagnosis detection, comprising:
Judgment module judges institute for receiving the instruction of the audit to the pathological examination of the pending project under any bar code Whether the detection system for stating pending project matches with preset detection system, and judge the bar code patient information whether Match with the limitation of preset data;
Range determination module, if the detection system for the pending project matches with preset detection system, and The patient information of the bar code matches with the limitation of preset data, it is determined that the seeking scope of preset matching entries;Wherein, The matching entries are the preparatory associated project with the pending project;
First searching module, if the seeking scope for preset matching entries includes the matching entries under same bar code, But when not including the matching entries under different bar codes, then M pathological examination of the matching entries is obtained according to first database; Wherein, M >=0;
Second searching module, if the seeking scope for preset matching entries include matching entries under same bar code and When matching entries under different bar codes, then N number of testing result of the matching entries is obtained according to first database;Wherein, N >= 0;
Third searching module, for as N=0, then being tied according to the X detection that the second database obtains the matching entries Fruit;Wherein, X >=0;Wherein, the second database includes the testing result of several projects under different bar codes;According to the second data The matching entries that library obtains need to meet preset condition, and the preset condition is other bar codes where the matching entries Patient information and the patient information of the bar code where the pending project match;
Auditing module is used for when M is greater than or equal to 1, N and is greater than or equal to 1 or X more than or equal to 1, according to described pending The contradiction condition of core project and matching entries judges that the pathological examination of the pending project and matching entries whether there is lance Shield obtains the auditing result of the pathological examination of the pending project;Wherein, contradiction if it exists, the then pending project The auditing result of pathological examination is that audit does not pass through;Contradiction if it does not exist, the then audit of the pathological examination of the pending project As a result pass through for audit.
Compared with prior art, compared with prior art, the audit device of pathological examination disclosed by the invention is according to reception That arrives instructs the audit of pending project, begins through that judgment module judges the detection system of the project and patient information is It is no to meet preset audit condition;If meeting, the seeking scope of the matching entries is determined by range determination module;If institute The seeking scope for stating matching entries is only limitted to same bar code, then described is searched in first database by the first searching module Pathological examination with project, if the seeking scope of the matching entries further includes the matching entries under different bar codes, by the Two searching modules search the pathological examination of the matching entries in first database and the second database, then by the audit mould Root tuber obtains the audit of the pathological examination of the pending project according to the contradiction condition of preset pending project and matching entries As a result, largely reducing the investment of manual analysis and comparison, error rate is reduced, the efficiency of audit is improved.
Detailed description of the invention
Fig. 1 is that the present invention wherein show in an embodiment by a kind of process of the checking method for hereditary disease gene diagnosis detection It is intended to.
Fig. 2 is that the present invention wherein show in an embodiment by a kind of process of the checking method for hereditary disease gene diagnosis detection It is intended to.
Fig. 3 is the flow diagram of step S4 in a wherein embodiment of the invention.
Fig. 4 is that the present invention wherein show in an embodiment by a kind of process of the checking method for hereditary disease gene diagnosis detection It is intended to.
Fig. 5 is the interface schematic diagram of the default auditing rule of the present invention
Fig. 6 is that pending project audits obstructed out-of-date early warning schematic diagram.
Fig. 7 is that the present invention wherein show in an embodiment by a kind of structure of the audit device for hereditary disease gene diagnosis detection It is intended to.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
It is a kind of stream for checking method for hereditary disease gene diagnosis detection that the embodiment of the present invention 1 provides referring to Fig. 1 Journey schematic diagram, comprising steps of
S1, the instruction of the audit to the pathological examination of the pending project under any bar code is received, judges the pending item Whether purpose detection system matches with preset detection system, and judge the bar code patient information whether with preset money Material limitation matches;
Wherein, the detection system includes device name, device signal and reagent producer etc., it is possible to understand that, it audited Journey need to consider the difference of result caused by the difference of detection system.Preferably, the patient information of the bar code and preset money Material limitation matches and specifically includes: the patient age of the bar code is in default range, the Gender of the bar code and pre- If gender limit the consistent and described corresponding information for hospital of bar code and preset hospital limit it is one of consistent or more Kind.
If detection system and the preset detection system of S2, the pending project match, and the patient of the bar code Information matches with the limitation of preset data, it is determined that the seeking scope of preset matching entries;Wherein, the matching entries are With the preparatory associated project of the pending project;
Wherein, same patient can correspond to different bar codes, according to the range of preset matching entries, can it is described to Matching entries are searched under audit project bar code, matching entries can also be searched under different bar codes, can get of same patient With project;
It should be understood that the pathological examination type of the pending project and matching entries includes numeric type and text-type, For example the testing result of high-risk HPV-DNA is numeric type, the pathological examination of human papilloma virus (HPV16/18-DNA) is text This type (negative or positive).
If the seeking scope of S3, preset matching entries include the matching entries under same bar code, but do not include different items Code under matching entries when, then M pathological examination of the matching entries is obtained according to first database;Wherein, M >=0;Its In, the first database includes the testing result of several projects under the bar code;
When M is 0, i.e., matching entries cannot be obtained under same bar code, therefore the pending project cannot be obtained The auditing result of pathological examination.
If the seeking scope of S4, preset matching entries include under matching entries and different bar codes under same bar code When with project, then N number of testing result of the matching entries is obtained according to first database;Wherein, N >=0;
S5, as N=0, then X testing result of the matching entries is obtained according to the second database;Wherein, X >=0; Wherein, the second database includes the testing result of several projects under different bar codes;The matching obtained according to the second database Project need to meet preset condition, patient information and institute of the preset condition for other bar codes where the matching entries The patient information for stating the bar code where pending project matches;
It, need to be by specimen information typing (including hospital, project and patient), sample point in the auditing system of the project of inspection Match, result typing, result is submitted, result audit, result ratifies and the process of result publication.In the present solution, first number Include having audited project according to library and the second database, that is, includes having audited the project that do not issue and announced project.Wherein The project of publication has also needed time limit requirement, and the time limit need to preset according to the difference of project, so that the occurrence obtained Mesh has reference significance.
S6, when M be greater than or equal to 1, N be greater than or equal to 1 or X be greater than or equal to 1 when, according to the pending project and Contradiction condition with project judges the pathological examinations of the pending project and matching entries with the presence or absence of contradiction, described in acquisition The auditing result of the pathological examination of pending project;Wherein, contradiction if it exists, then the pathological examination of the pending project is examined Core result is that audit does not pass through;Contradiction if it does not exist, then the auditing result of the pathological examination of the pending project is that audit is logical It crosses.
Wherein, the contradiction condition of pending project and matching entries, can experimental the principles of science preset;
When it is implemented, instructing according to the audit to pending project received, start the detection for judging the project Whether system and patient information meet preset audit condition;If meeting, it is determined that the seeking scope of the matching entries;If institute The seeking scope for stating matching entries is only limitted to same bar code, then the pathology knot of the matching entries is searched in first database Fruit first searches the matching in first database under same bar code if the seeking scope of matching entries is extended under different bar codes Project begins looking for different items in the second database when searching in first database less than matching entries under same bar code Matching entries under code obtain the pending project according to the contradiction condition of preset pending project and matching entries The auditing result of pathological examination largely reduces the investment of manual analysis and comparison, reduces error rate, improves audit Efficiency.
Since multiple pathological examinations of pending project can be received under same bar code, a pathological examination is often received, It just audits whether the primary pathological examination passes through, sending whether can be audited according to pathological examination each in pending project and reminds letter Number, therefore on the basis of the above embodiments, as shown in Fig. 2, another preferred embodiment further comprises the steps of:
S7, according to the auditing result of each pathological examination in the pending project, issue early warning;Wherein, if institute It is at least obstructed out-of-date to audit in the presence of the early warning result of a pathological examination to state in pending project, issues that early warning is unacceptable to be mentioned Show;If the auditing result of each pathological examination is that audit passes through in the pending project, the prompt that early warning passes through is issued;
S8, according to the early warning of pending project each under the bar code as a result, issuing early warning;Wherein, if the item It is at least obstructed out-of-date for early warning in the presence of the early warning result of a pending project under code, issue the unacceptable prompt of early warning; If the early warning result of each pending project is that early warning passes through under the bar code, the prompt that early warning passes through is issued.
Through the above scheme, it can be achieved that gradient is reminded in concept and range early warning from big to small, when barcode label be early warning not By when, such as labeled as it is red when, then it represents that there is the project that the audit fails under the bar code;It can get according to the bar code Check that the project that the audit fails, the project equally mark not pass through, it can by the unacceptable project of the early warning Find the pathological examination of abnormality.On the other hand, when barcode label passes through for early warning, is such as labeled as green, then it represents that Project under the bar code, which is audited, to be passed through;When barcode label is empty, when such as white, then it represents that all items under the bar code Auditing result is sky.Certainly, there is also a kind of situations is, when there is the project that passes through of audit under same bar code and auditing result is It is then admixture by the barcode label when project of sky.The above process is suitable for the auditing system of inspection project, can subtract While few labor workload, accuracy is improved, there is important directive significance.
Wherein, because the physiology of people is to be in continuous change procedure, therefore pathological examination has timeliness.It is setting When seeking scope, first database and the second database need to set the period of the published data of lookup, to guarantee occurrence Purpose pathological examination has reference significance.
Preferably, the contradiction condition of pending project and matching entries is stated specifically: the pathology knot of the pending project Fruit is that the pathological examination of ascendant trend and the matching entries is downward trend;Wherein, the ascendant trend is more than preset The upper limit threshold of term of reference, the downward trend are the lower threshold lower than the preset term of reference;It is described pending The pathological examination type of project and matching entries is numeric type.It should be understood that the term of reference be Scientific summarization just Normal range.
Preferably, the contradiction condition of the pending project and matching entries are as follows: the pathological examination of the pending project Less than preset numerical value and the pathological examination of matching entries it is consistent with preset text;Wherein, the pathology knot of the matching entries Fruit type is numeric type, and the pathological examination type of the matching entries is text-type.
In another preferred embodiment, the matching entries include first item and second item, the pending project With the contradiction condition of matching entries specifically: the pathological examination of the pending project is less than preset numerical value, first item Pathological examination is consistent with preset text and the pathological examination of second item is greater than preset numerical value;Wherein, described pending The pathological examination type of project and second item is numeric type, and the pathological examination type of the first item is text-type.
Preferably, as shown in figure 3, the pathological examination for obtaining the matching entries according to the second database in step S4 is specific Are as follows:
S41, other bar codes where the pathological examination of the matching entries are obtained according to second database;
Other bar codes described in S42, acquisition obtain corresponding patient information, by the patient information of other bar codes with it is described The patient information of bar code is compared, when the patient condition of other bar codes and the patient condition of the bar code meet hospital Match, when gender matching, name matches and the difference at age are less than preset threshold value, then obtains described according to other described bar codes Pathological examination with project.
In the step, after finding other bar codes of same patient, the matching can be searched under other described bar codes The pathological examination of project, using as judging whether the pathological examination of the first item reasonably refers to.
Above-mentioned steps are looked by first searching other bar codes of same patient in historical record, then under other described bar codes Look for matching entries, it is possible to understand that, in another preferred embodiment, the matching entries can also be obtained in the second database Each pathological examination, then judge bar code where the pathological examination of the matching entries whether the bar code where with pending project Match.
In medical system, when the pending project meets specific condition, in order to make a definite diagnosis a certain disease, need to increase Matching entries audit the secondary proof passed through as the pending project, therefore, as shown in figure 4, a preferred embodiment is also wrapped Include step:
If S9, X are equal to 0, judge whether the pathological examination of the pending project meets preset implied condition;
If N is equal to 0, there is no the pathological examinations of the matching entries of same patient.
If the pathological examination of S10, the pending project meet preset implied condition, alerting signal is issued;Wherein, institute Alerting signal is stated for reminding the pathological examination for receiving the matching entries.
Wherein, the implied condition is usually the voucher for diagnosing a certain disease, for example two double of results are that great three positive can be made It, can not for a kind of voucher for diagnosing hepatitis B, but when the pathological examination of the pending project meets preset implied condition Determine whether the pathological examination is accurate, when the pathological examination inaccuracy, it is most likely that there is a situation where disease mistaken diagnosis.Therefore it is The accuracy of the above-mentioned pathological examination of verifying, need to issue alerting signal to remind the pathological examination for receiving the matching entries, from And the pathological examination for obtaining the matching entries also can be used as the assistant that disease is made a definite diagnosis as the standard for auditing the first item Card.For example, within a preset time period, system does not receive liver function seven, then can send out when two double of results are great three positive Alerting signal out.
It is previously mentioned, it, need to be by specimen information typing (including hospital, project and disease in the auditing system of the project of inspection People), sample distribution, result typing, result submit, result audit, result approval and result publication process.It is preferably implemented one In example, when the publication for receiving any project to be released instructs, it is pre- to check whether the pathological examination of band publication project meets If conditions for diagnostics show corresponding diagnosis content if meet preset conditions for diagnostics.
It should be noted that the above-mentioned checking method for hereditary disease gene diagnosis detection is suitable for preset audit rule Auditing system then, as shown in figure 5,1. being limited for preset data, it can be seen that it is female that data, which is limited to gender, and the age needs big It is 2. preset detection system, including device name, device model and reagent producer in 20 years old, is 3. combined for the audit of setting, 4. for pending project and matching entries that audit combination includes, including HbA2, β-thalassemia Genotyping (17 kinds of mutation) and β-thalassemia (HBB) sequencing, the pending project and matching entries are relative concept, and It does not specify;5. the seeking scope of the matching entries for setting indicates that seeking scope only includes same item when being set as 0 day Matching entries under code;When being set as non-zero day, indicate that the range searched includes the occurrence under same bar code and under different bar codes 6. mesh is the logical contradiction relationship of setting, then think described when pending project and matching entries meet logical contradiction relationship Pending project audit does not pass through.Based on the auditing rule in Fig. 5, the auditing result of pending project can be automatically obtained.Wherein, It is 6. the relationship of the normal condition of setting when choosing " non-" in Fig. 5, i.e., is normal condition when meeting logical relation 6., It is abnormality when being unsatisfactory for logical relation 6..
For example, as shown in fig. 6, matching entries are β-thalassemia genes if pending project is HbA2 Parting (17 kinds of mutation) and β-thalassemia (HBB) sequencing, if HbA2 result is poor greater than the Mediterranean 5, β- Blood Genotyping (17 kinds of mutation) result that result is " mutation is not detected ", β-thalassemia (HBB) is sequenced is feminine gender, Pathogenic gene mutation is not detected, then the auditing result of HbA2 is that audit does not pass through, then three under the bar code A project issues early warning, and the early warning of display is thalassemia testing result contradiction, and determines that the bar code is Audit does not pass through, and shows that early warning does not pass through.In addition, when the state of the project under the bar code is that audit passes through, this Code is shown as early warning and passes through;When the state of the project of the bar code include audit by and when not auditing, the bar code be shown as to Confirmation;When the state of the project of the bar code is not audit, which is shown as no early warning.Wherein, early warning does not pass through, in advance Police passes through, state to be confirmed and without early warning need to be distinguished by different colors.
It is a kind of structural schematic diagram of the audit device of present invention pathological examination that wherein an embodiment provides referring to Fig. 7, Include:
Judgment module 101, for receiving the instruction of the audit to the pathological examination of the pending project under any bar code, judgement Whether the detection system of the pending project matches with preset detection system, and judges that the patient information of the bar code is It is no to match with the limitation of preset data;
Range determination module 102, if the detection system for the pending project matches with preset detection system, And the patient information of the bar code matches with the limitation of preset data, it is determined that the seeking scope of preset matching entries;Its In, the matching entries are the preparatory associated project with the pending project;
First searching module 103, if the seeking scope for preset matching entries includes the occurrence under same bar code Mesh, but when not including the matching entries under different bar codes, then M pathology knot of the matching entries is obtained according to first database Fruit;Wherein, M >=0;
Second searching module 104, if for including under same bar code for the seeking scope of preset matching entries When with matching entries under project and different bar codes, then N number of testing result of the matching entries is obtained according to first database; Wherein, N >=0;
Third searching module 105, for as N=0, then obtaining X inspection of the matching entries according to the second database Survey result;Wherein, X >=0;Wherein, the second database includes the testing result of several projects under different bar codes;According to second The matching entries that database obtains need to meet preset condition, and the preset condition is other where the matching entries The patient information of code and the patient information of the bar code where the pending project match;
Auditing module 106 is used for when M is greater than or equal to 1, N and is greater than or equal to 1 or X more than or equal to 1, according to described The contradiction condition of pending project and matching entries judges that the pathological examination of the pending project and matching entries whether there is Contradiction obtains the auditing result of the pathological examination of the pending project;Wherein, contradiction if it exists, the then pending project Pathological examination auditing result be audit do not pass through;Contradiction if it does not exist, then the pathological examination of the pending project is careful Core result is that audit passes through.
To sum up, the checking method disclosed by the invention for hereditary disease gene diagnosis detection is according to receiving to pending The audit of project instructs, and starts the detection system for judging the project and whether patient information meets preset audit condition;If Meet, it is determined that the seeking scope of the matching entries;If the seeking scope of the matching entries is only limitted to same bar code, The pathological examination that the matching entries are searched in first database, if the seeking scope of matching entries is extended under different bar codes When, the matching entries in first database under same bar code are first searched, when searching in first database less than under same bar code When matching entries, begin looking in the second database the matching entries under different bar codes, according to preset pending project and Contradiction condition with project obtains the auditing result of the pathological examination of the pending project, largely reduces artificial Analysis and the investment compared, reduce error rate, improve the efficiency of audit.
The above is a preferred embodiment of the present invention, it is noted that for those skilled in the art For, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also considered as Protection scope of the present invention.

Claims (8)

1. a kind of checking method for hereditary disease gene diagnosis detection, which is characterized in that comprising steps of
It receives the audit to the pathological examination of the pending project under any bar code to instruct, judges the detection of the pending project Whether system matches with preset detection system, and judge the bar code patient information whether with preset data limit phase Matching;
If the detection system of the pending project matches with preset detection system, and the patient information of the bar code and pre- If data limitation match, it is determined that the seeking scope of preset matching entries;Wherein, the matching entries be with it is described to The preparatory associated project of audit project;
If the seeking scope of preset matching entries includes the matching entries under same bar code, but does not include under different bar codes When with project, then M pathological examination of the matching entries is obtained according to first database;Wherein, M >=0;Wherein, described One database includes the testing result of several projects under the bar code;
If the seeking scope of preset matching entries includes the matching entries under matching entries and different bar codes under same bar code When, then N number of testing result of the matching entries is obtained according to first database;Wherein, N >=0;
As N=0, then X testing result of the matching entries is obtained according to the second database;Wherein, X >=0;Wherein, Two databases include the testing result of several projects under different bar codes;It need to be expired according to the matching entries that the second database obtains The preset condition of foot, the preset condition be other bar codes where the matching entries patient information with it is described pending The patient information of bar code where project matches;
When M, which is greater than or equal to 1, N, is greater than or equal to 1 or X more than or equal to 1, according to the pending project and matching entries Contradiction condition, judge that the pathological examination of the pending project and matching entries with the presence or absence of contradiction, obtains described pending The auditing result of the pathological examination of project;Wherein, contradiction if it exists, the then auditing result of the pathological examination of the pending project Do not pass through for audit;Contradiction if it does not exist, then the auditing result of the pathological examination of the pending project is that audit passes through;
If X is equal to 0, judge whether the pathological examination of the pending project meets preset implied condition;
If the pathological examination of the pending project meets preset implied condition, alerting signal is issued;Wherein, the prompting letter Number for reminding the pathological examination for receiving the matching entries;
The pathological examination that the matching entries are obtained according to the second database specifically:
Other bar codes where the pathological examination of the matching entries are obtained according to second database;
It obtains other described bar codes and obtains corresponding patient information, by the trouble of the patient information of other bar codes and the bar code Person's information is compared, and matches when patient condition and the patient condition of the bar code of other bar codes meet hospital, gender When matching, name matches and the difference at age are less than preset threshold value, then the matching entries are obtained according to other described bar codes Pathological examination.
2. the checking method for hereditary disease gene diagnosis detection as described in claim 1, which is characterized in that described pending The pathological examination type of project and matching entries includes numeric type and text-type.
3. the checking method for hereditary disease gene diagnosis detection as claimed in claim 2, which is characterized in that described pending The contradiction condition of project and matching entries specifically:
The pathological examination of the pending project is that the pathological examination of ascendant trend and the matching entries is downward trend;Its In, the ascendant trend is the upper limit threshold more than preset term of reference, and the downward trend is lower than the preset ginseng Examine the lower threshold of range;The pathological examination type of the pending project and matching entries is numeric type.
4. the checking method for hereditary disease gene diagnosis detection as claimed in claim 2, which is characterized in that described pending The contradiction condition of project and matching entries are as follows:
The pathological examination of the pending project is less than preset numerical value and the pathological examination of matching entries and preset text one It causes;Wherein, the pathological examination type of the matching entries is numeric type, and the pathological examination type of the matching entries is text Type.
5. the checking method for hereditary disease gene diagnosis detection as claimed in claim 2, which is characterized in that the occurrence Mesh includes first item and second item, the contradiction condition of the pending project and matching entries specifically:
It is consistent with preset text that the pathological examination of the pending project is less than preset numerical value, the pathological examination of first item And the pathological examination of second item is greater than preset numerical value;Wherein, the pathological examination of the pending project and second item Type is numeric type, and the pathological examination type of the first item is text-type.
6. the checking method for hereditary disease gene diagnosis detection as described in claim 1, which is characterized in that the bar code The limitation of patient information and preset data, which matches, to be specifically included: the patient age of the bar code in default range, it is described The Gender of bar code and preset gender limit the consistent and described corresponding information for hospital of bar code and the limitation of preset hospital It is one of consistent or a variety of.
7. the checking method for hereditary disease gene diagnosis detection as described in claim 1, which is characterized in that further include step It is rapid:
According to the auditing result of each pathological examination in the pending project, early warning is issued;Wherein, if it is described pending It is at least obstructed out-of-date to audit in the presence of the early warning result of a pathological examination in project, issue the unacceptable prompt of early warning;If institute When the auditing result for stating each pathological examination in pending project is that audit passes through, the prompt that early warning passes through is issued;
According to the early warning of pending project each under the bar code as a result, issuing early warning;Wherein, if under the bar code at least It is that early warning is obstructed out-of-date there are the early warning result of a pending project, issues the unacceptable prompt of early warning;If the item When the early warning result of each pending project is that early warning passes through under code, the prompt that early warning passes through is issued.
8. a kind of audit device for hereditary disease gene diagnosis detection characterized by comprising
Judgment module, for receiving the instruction of the audit to the pathological examination of the pending project under any bar code, judgement it is described to Whether the detection system of audit project matches with preset detection system, and judge the bar code patient information whether in advance If data limitation match;
Range determination module, if the detection system for the pending project matches with preset detection system, and described The patient information of bar code matches with the limitation of preset data, it is determined that the seeking scope of preset matching entries;Wherein, described Matching entries are the preparatory associated project with the pending project;
First searching module, if the seeking scope for preset matching entries includes the matching entries under same bar code, but not When including matching entries under different bar codes, then M pathological examination of the matching entries is obtained according to first database;Its In, M >=0;
Second searching module, if the seeking scope for preset matching entries includes matching entries and difference under same bar code When matching entries under bar code, then N number of testing result of the matching entries is obtained according to first database;Wherein, N >=0;
Third searching module, for as N=0, then obtaining X testing result of the matching entries according to the second database; Wherein, X >=0;Wherein, the second database includes the testing result of several projects under different bar codes;According to the second database The matching entries of acquisition need to meet preset condition, and the preset condition is the trouble of other bar codes where the matching entries Person's information and the patient information of the bar code where the pending project match;It is described to obtain described according to the second database Pathological examination with project specifically:
Other bar codes where the pathological examination of the matching entries are obtained according to second database;
It obtains other described bar codes and obtains corresponding patient information, by the trouble of the patient information of other bar codes and the bar code Person's information is compared, and matches when patient condition and the patient condition of the bar code of other bar codes meet hospital, gender When matching, name matches and the difference at age are less than preset threshold value, then the matching entries are obtained according to other described bar codes Pathological examination;
Auditing module is used for when M is greater than or equal to 1, N and is greater than or equal to 1 or X more than or equal to 1, according to the pending item The contradiction condition of mesh and matching entries judges that the pathological examination of the pending project and matching entries whether there is contradiction, obtains Obtain the auditing result of the pathological examination of the pending project;Wherein, contradiction if it exists, then the pathology knot of the pending project The auditing result of fruit is that audit does not pass through;Contradiction if it does not exist, then the auditing result of the pathological examination of the pending project be Audit passes through.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106126958A (en) * 2016-07-06 2016-11-16 温冬梅 Health Service Laboratory biochemistry test automatic auditing method and system
CN106156502A (en) * 2016-07-05 2016-11-23 东软集团股份有限公司 The appraisal procedure of a kind of report examination & verification and device
CN106529202A (en) * 2016-12-20 2017-03-22 深圳金域医学检验所有限公司 Intelligent auditing system and method for medical specimen testing

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106156502A (en) * 2016-07-05 2016-11-23 东软集团股份有限公司 The appraisal procedure of a kind of report examination & verification and device
CN106126958A (en) * 2016-07-06 2016-11-16 温冬梅 Health Service Laboratory biochemistry test automatic auditing method and system
CN106529202A (en) * 2016-12-20 2017-03-22 深圳金域医学检验所有限公司 Intelligent auditing system and method for medical specimen testing

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