CN107173580A - A kind of live pig getting fat disease-resistant feed and preparation method thereof - Google Patents
A kind of live pig getting fat disease-resistant feed and preparation method thereof Download PDFInfo
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Abstract
The present invention proposes a kind of live pig getting fat disease-resistant feed, and its raw material includes wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal, oyster shell whiting, bone meal, oil cake of flax seed, kudzuvine root starch, tapioca starch, guar gum, konjac glucomannan, butter, pleurotus eryngii bacterium, modified carried medicine sustained-release agent and mould proof auxiliary agent.The present invention also proposes a kind of preparation method of above-mentioned live pig getting fat disease-resistant feed.The feedstuff for live pigs that the present invention is prepared has getting fat and disease-resistant effect.
Description
Technical field
The present invention relates to the technical field of feed, more particularly to a kind of live pig getting fat disease-resistant feed and preparation method thereof.
Background technology
In recent years, developing rapidly with sheep raising aquaculture, various feedstuff for live pigs are also developed rapidly therewith, current market
Various feedstuff for live pigs it is various in style, but directly resulted in whole due to the uneven of feedstuff for live pigs material quality in the prior art
Body diets of different nutrition level is not high, greatly influences the daily gain and fanning economics of live pig, and mixing inequality causes raw material
Feeding is uneven, and nutriment intake is serious uneven, causes live pig nutrient imbalance, it is impossible to which fully meeting the growth of live pig needs
Will.Therefore, feedstuff for live pigs and its additive need further perfect.
The content of the invention
To solve technical problem present in background technology, the present invention proposes a kind of live pig getting fat disease-resistant feed and its preparation
Method, the feedstuff for live pigs prepared has getting fat and disease-resistant effect.
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：25-45 parts of wheat flour, beans
15-35 parts of slag, 4-9 parts of rice bran, 2-5 parts of rape cake, 10-30 parts of wheat stalk, 4-9 parts of sweet potato vine, 2-8 parts of Microcystis aeruginosa, marine alga
2-12 parts, 3-6 parts of dried silkworm chrysalis meal, 3-9 parts of fish meal, 3-5 parts of oyster shell whiting, 10-40 parts of bone meal, 15-35 parts of oil cake of flax seed, 3-9 parts of kudzuvine root starch,
2-5 parts of tapioca starch, 4-8 parts of guar gum, 2-5 parts of konjac glucomannan, 2-6 parts of butter, 1-6 parts of pleurotus eryngii bacterium, modified carried medicine sustained-release agent 5-15
Part, mould proof auxiliary agent 3-9 parts.
Preferably, the raw material of modified carried medicine sustained-release agent includes by weight：5-15 parts of lactic acid, 3-6 parts of stannous chloride, collagen
2-5 parts of albumen, 1-3 parts of dimethyl sulfoxide (DMSO), N, 2-5 parts of N- dicyclohexylcarbodiimides, 0.2-0.4 parts of Enrofloxacin.
Preferably, modified carried medicine sustained-release agent is prepared by following technique：Lactic acid is heated up, is removed water, is then heated up, remove
Water, under nitrogen protection, adds stannous chloride and is well mixed, heat up, and insulation then continues to heating, and then insulation adds third
Ketone, is washed after precipitation, is dried to constant weight, is cooled to room temperature, then adds collagen and dimethyl sulfoxide (DMSO) is well mixed, stir
Mix, heat up, insulation adds N, and N- dicyclohexylcarbodiimides and Enrofloxacin are well mixed, and stirring is cooled to room temperature and changed
Property carried medicine sustained-release agent.
Preferably, modified carried medicine sustained-release agent is prepared by following technique：Lactic acid is warming up to 110-130 DEG C, absolute pressure
0.5-1.5h is removed water under power 65-75Kpa, is then heated under 140-160 DEG C, absolute pressure 25-35Kpa, 1-3h is removed water, in nitrogen
Under gas shielded, add stannous chloride and be well mixed, be warming up to 160-180 DEG C, be incubated 5-15min, then continue to be warming up to 180-
190 DEG C, absolute pressure 4-6Kpa is incubated 10-12h, then adds acetone, is washed after precipitation, is dried in 30-50 DEG C to constant weight,
Room temperature is cooled to, collagen is then added and dimethyl sulfoxide (DMSO) is well mixed, 20- is stirred in 1200-1400r/min rotating speeds
40min, is warming up to 20-25 DEG C, is incubated 10-20min, adds N, and N- dicyclohexylcarbodiimides and Enrofloxacin are well mixed,
1-2h is stirred in 650-850r/min rotating speeds, room temperature is cooled to and obtains being modified carried medicine sustained-release agent.
Preferably, the raw material of mould proof auxiliary agent includes by weight：3-9 parts of calcium nitrate tetrahydrate, 5-15 parts of diammonium hydrogen phosphate,
10-20 parts of distilled water, 4-8 parts of dopamine hydrochloride, 1-5 parts of silver nitrate.
Preferably, mould proof auxiliary agent is prepared by following technique：Calcium nitrate tetrahydrate, diammonium hydrogen phosphate and distilled water are mixed
Close uniform, then adjust pH with ammoniacal liquor, then heat up, be incubated, stirring is cooled to room temperature, be subsequently added into dopamine hydrochloride and mix
Close uniform, stir at room temperature, then add silver nitrate and be well mixed, stir, washing, freeze-drying obtains mould proof auxiliary agent.
Preferably, mould proof auxiliary agent is prepared by following technique：Calcium nitrate tetrahydrate, diammonium hydrogen phosphate and distilled water are mixed
Close uniform, then adjust pH to 9.8-10.2 with ammoniacal liquor, be then warming up to 85-95 DEG C, 20-30min is incubated, in 650-850r/
Min rotating speeds stir 1-3h, are cooled to room temperature, are subsequently added into dopamine hydrochloride and are well mixed, at room temperature in 650-850r/min
Rotating speed stirs 3-9min, then adds silver nitrate and is well mixed, 2-4h is stirred in 1500-2500r/min rotating speeds, washes, freezing
It is dried to obtain mould proof auxiliary agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross and material A are obtained after 100-200 mesh sieve, oil cake of flax seed, Pueraria lobota are added into material A
Powder and pleurotus eryngii bacterium, ferment 10-20d in 60-80 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent are well mixed to obtain material C, and material C is then concentrated to give into material A in 50-60 DEG C, then by material A in
90-105 DEG C of dry 2-6h, is cooled to room temperature, and the granular live pig getting fat disease-resistant feed of 20-40 mesh is made through comminutor.
A kind of live pig getting fat disease-resistant feed of the present invention, its raw material includes wheat flour, bean dregs, rice bran, rape cake, Wheat Straw
Stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal, oyster shell whiting, bone meal, oil cake of flax seed, kudzuvine root starch, tapioca starch, guar gum, konjac glucomannan,
Butter, pleurotus eryngii bacterium, modified carried medicine sustained-release agent and mould proof auxiliary agent.Wherein using wheat flour as major ingredient, bean dregs, rice bran, vegetable seed are mixed
Cake, wheat stalk, sweet potato vine, Microcystis aeruginosa and marine alga are that starch and crude fibre are originated, using dried silkworm chrysalis meal and fish meal as protein source,
Using guar gum and konjac glucomannan as moulding mixture is helped, with pleurotus eryngii bacterium zymophyte, it is sustained and anti-with being modified carried medicine sustained-release agent and mould proof auxiliary agent
Mould auxiliary agent, by the addition of above-mentioned auxiliary material, the feedstuff for live pigs prepared is applied in pig-breeding, disclosure satisfy that growth growth
The nutritional need of process, effectively increases the resistance against diseases of live pig, improves the survival rate of live pig.The life that the present invention is prepared
Pig feed has getting fat and disease-resistant effect.Wherein, modified carried medicine sustained-release agent removes water by the way that lactic acid is heated up, then heats up, remove
Water, under nitrogen protection, adds stannous chloride and is well mixed, heat up, and insulation then continues to heating, and then insulation adds third
Ketone, is washed after precipitation, is dried to constant weight, is cooled to room temperature, then adds collagen and dimethyl sulfoxide (DMSO) is well mixed, stir
Mix, heat up, insulation adds N, and N- dicyclohexylcarbodiimides and Enrofloxacin are well mixed, and stirring is cooled to room temperature and changed
Property carried medicine sustained-release agent.Microballoon send neck as the main carriers type of drug delivery system in drug controlled release and drug targeting
Domain has a wide range of applications, and PLA is because it is non-toxic and the biology property explained, because the hydrophily on PLA surface is poor, no
Beneficial to cell adherence, absorption of the cell to medicine is reduced, drug effect is reduced, because the acid self-catalysis of PLA itself is degraded
So that insoluble drug release is difficult to control to, the clinical practice of PLA drug bearing microsphere is limited, by polydactyl acid, and by En Nuosha
Star is rubbed in modified PLA, in the feedstuff for live pigs for applying to the present invention, enables to Enrofloxacin can be in live pig
After the feedstuff for live pigs for having eaten the present invention, efficient absorption medicine improves the resistance against diseases of pig.Wherein, mould proof auxiliary agent is improved four
Nitric hydrate calcium, diammonium hydrogen phosphate and distilled water are well mixed, then adjust pH with ammoniacal liquor, then heat up, and are incubated, and stirring is cold
But to room temperature, it is subsequently added into dopamine hydrochloride and is well mixed, stir at room temperature, then adds silver nitrate and be well mixed, stirring,
Washing, freeze-drying obtains mould proof auxiliary agent, by using calcium nitrate tetrahydrate and diammonium hydrogen phosphate, under the regulation of ammoniacal liquor, system
For hydroxyapatite, and under the modification of dopamine hydrochloride, graft modification is carried out in silver nitrate, obtained mould proof auxiliary agent fortune
Use in feedstuff for live pigs of the present invention, effectively increase the fungicidal properties of feedstuff for live pigs, extend the service life of feedstuff for live pigs.
Embodiment
The present invention is described in detail with reference to specific embodiment, it should be appreciated that embodiment is served only for illustrating this hair
It is bright, rather than for limiting the invention, any modification made on the basis of the present invention, equivalent substitution etc. are in this hair
In bright protection domain.
Embodiment 1
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：35 parts of wheat flour, bean dregs 25
Part, 6.5 parts of rice bran, 3.5 parts of rape cake, 20 parts of wheat stalk, 6.5 parts of sweet potato vine, 5 parts of Microcystis aeruginosa, 7 parts of marine alga, dried silkworm chrysalis meal 4.5
Part, 6 parts of fish meal, 4 parts of oyster shell whiting, 25 parts of bone meal, 25 parts of oil cake of flax seed, 6 parts of kudzuvine root starch, 3.5 parts of tapioca starch, 6 parts of guar gum, konjac glucomannan
3.5 parts, 4 parts of butter, 3.5 parts of pleurotus eryngii bacterium, modified 10 parts of carried medicine sustained-release agent, 6 parts of mould proof auxiliary agent.
Modified carried medicine sustained-release agent is prepared by following technique：10 parts of lactic acid are warming up to 120 DEG C, absolute pressure by weight
1h is removed water under power 70Kpa, is then heated under 150 DEG C, absolute pressure 30Kpa, 2h is removed water, under nitrogen protection, 4.5 parts are added
Stannous chloride is well mixed, and is warming up to 170 DEG C, is incubated 10min, then continues to be warming up to 185 DEG C, absolute pressure 5Kpa, insulation
11h, then adds acetone, is washed after precipitation, is dried in 40 DEG C to constant weight, is cooled to room temperature, then adds 3.5 parts of collagens
It is well mixed with 2 parts of dimethyl sulfoxide (DMSO)s, 30min is stirred in 1300r/min rotating speeds, 22.5 DEG C are warming up to, 15min is incubated, added
3.5 parts of N, N- dicyclohexylcarbodiimides and 0.3 part of Enrofloxacin are well mixed, and 1.5h, cooling are stirred in 750r/min rotating speeds
Obtain being modified carried medicine sustained-release agent to room temperature.
Mould proof auxiliary agent is prepared by following technique：By weight by 6 parts of calcium nitrate tetrahydrates, 10 parts of diammonium hydrogen phosphates and
15 parts of distilled water are well mixed, and then adjust pH to 10 with ammoniacal liquor, are then warming up to 90 DEG C, are incubated 25min, are turned in 750r/min
Speed stirring 2h, is cooled to room temperature, is subsequently added into 6 parts of dopamine hydrochlorides and is well mixed, is stirred at room temperature in 750r/min rotating speeds
6min, then adds 3 parts of silver nitrates and is well mixed, 3h is stirred in 2000r/min rotating speeds, washing, freeze-drying obtains mould proof help
Agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross 150 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 15d in 70 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent are well mixed to obtain material C, and material C then is concentrated to give into material A in 55 DEG C, then by material A in
97.5 DEG C of dry 4h, are cooled to room temperature, and the granular live pig getting fat disease-resistant feed of 30 mesh is made through comminutor.
Embodiment 2
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：25 parts of wheat flour, bean dregs 35
Part, 4 parts of rice bran, 5 parts of rape cake, 10 parts of wheat stalk, 9 parts of sweet potato vine, 2 parts of Microcystis aeruginosa, 12 parts of marine alga, 3 parts of dried silkworm chrysalis meal, fish meal
9 parts, 3 parts of oyster shell whiting, 40 parts of bone meal, 15 parts of oil cake of flax seed, 9 parts of kudzuvine root starch, 2 parts of tapioca starch, 8 parts of guar gum, 2 parts of konjac glucomannan, butter 6
Part, 1 part of pleurotus eryngii bacterium, modified 15 parts of carried medicine sustained-release agent, 3 parts of mould proof auxiliary agent.
Modified carried medicine sustained-release agent is prepared by following technique：5 parts of lactic acid are warming up to 130 DEG C, absolute pressure by weight
1.5h is removed water under power 65Kpa, is then heated under 140 DEG C, absolute pressure 35Kpa, 1h is removed water, under nitrogen protection, 6 parts are added
Stannous chloride is well mixed, and is warming up to 160 DEG C, is incubated 15min, then continues to be warming up to 180 DEG C, absolute pressure 6Kpa, insulation
10h, then adds acetone, is washed after precipitation, is dried in 50 DEG C to constant weight, is cooled to room temperature, then add 2 parts of collagens and
3 parts of dimethyl sulfoxide (DMSO)s are well mixed, and 40min is stirred in 1200r/min rotating speeds, are warming up to 20 DEG C, are incubated 20min, add 2 parts of N,
N- dicyclohexylcarbodiimides and 0.4 part of Enrofloxacin are well mixed, and are stirred 2h in 650r/min rotating speeds, are cooled to room temperature and obtain
Modified carried medicine sustained-release agent.
Mould proof auxiliary agent is prepared by following technique：By weight by 3 parts of calcium nitrate tetrahydrates, 15 parts of diammonium hydrogen phosphates and
10 parts of distilled water are well mixed, and then adjust pH to 10.2 with ammoniacal liquor, are then warming up to 85 DEG C, 30min are incubated, in 650r/min
Rotating speed stirs 3h, is cooled to room temperature, is subsequently added into 4 parts of dopamine hydrochlorides and is well mixed, is stirred at room temperature in 850r/min rotating speeds
3min is mixed, 5 parts of silver nitrates is then added and is well mixed, 4h is stirred in 1500r/min rotating speeds, washing, freeze-drying obtains mould proof
Auxiliary agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross 100 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 10d in 80 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent, which are well mixed, obtains material C, material C then is concentrated to give into material A in 60 DEG C, then by material A in 90
DEG C dry 6h, be cooled to room temperature, the granular live pig getting fat disease-resistant feed of 20 mesh be made through comminutor.
Embodiment 3
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：45 parts of wheat flour, bean dregs 15
Part, 9 parts of rice bran, 2 parts of rape cake, 30 parts of wheat stalk, 4 parts of sweet potato vine, 8 parts of Microcystis aeruginosa, 2 parts of marine alga, 6 parts of dried silkworm chrysalis meal, fish meal 3
Part, 5 parts of oyster shell whiting, 10 parts of bone meal, 35 parts of oil cake of flax seed, 3 parts of kudzuvine root starch, 5 parts of tapioca starch, 4 parts of guar gum, 5 parts of konjac glucomannan, 2 parts of butter,
6 parts of pleurotus eryngii bacterium, modified 5 parts of carried medicine sustained-release agent, 9 parts of mould proof auxiliary agent.
Modified carried medicine sustained-release agent is prepared by following technique：15 parts of lactic acid are warming up to 110 DEG C, absolute pressure by weight
0.5h is removed water under power 75Kpa, is then heated under 160 DEG C, absolute pressure 25Kpa, 3h is removed water, under nitrogen protection, 3 parts are added
Stannous chloride is well mixed, and is warming up to 180 DEG C, is incubated 5min, then continues to be warming up to 190 DEG C, absolute pressure 4Kpa, insulation
12h, then adds acetone, is washed after precipitation, is dried in 30 DEG C to constant weight, is cooled to room temperature, then add 5 parts of collagens and
1 part of dimethyl sulfoxide (DMSO) is well mixed, and 20min is stirred in 1400r/min rotating speeds, is warming up to 25 DEG C, is incubated 10min, adds 5 parts of N,
N- dicyclohexylcarbodiimides and 0.2 part of Enrofloxacin are well mixed, and are stirred 1h in 850r/min rotating speeds, are cooled to room temperature and obtain
Modified carried medicine sustained-release agent.
Mould proof auxiliary agent is prepared by following technique：By weight by 9 parts of calcium nitrate tetrahydrates, 5 parts of diammonium hydrogen phosphates and
20 parts of distilled water are well mixed, and then adjust pH to 9.8 with ammoniacal liquor, are then warming up to 95 DEG C, 20min are incubated, in 850r/min
Rotating speed stirs 1h, is cooled to room temperature, is subsequently added into 8 parts of dopamine hydrochlorides and is well mixed, is stirred at room temperature in 650r/min rotating speeds
9min is mixed, 1 part of silver nitrate is then added and is well mixed, 2h is stirred in 2500r/min rotating speeds, washing, freeze-drying obtains mould proof
Auxiliary agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross 200 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 20d in 60 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent, which are well mixed, obtains material C, material C then is concentrated to give into material A in 50 DEG C, then by material A in 105
DEG C dry 2h, be cooled to room temperature, the granular live pig getting fat disease-resistant feed of 40 mesh be made through comminutor.
Embodiment 4
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：28 parts of wheat flour, bean dregs 32
Part, 5 parts of rice bran, 4 parts of rape cake, 15 parts of wheat stalk, 8 parts of sweet potato vine, 3 parts of Microcystis aeruginosa, 10 parts of marine alga, 4 parts of dried silkworm chrysalis meal, fish meal
8 parts, 3.5 parts of oyster shell whiting, 35 parts of bone meal, 18 parts of oil cake of flax seed, 8 parts of kudzuvine root starch, 3 parts of tapioca starch, 7 parts of guar gum, 3 parts of konjac glucomannan, butter 5
Part, 2 parts of pleurotus eryngii bacterium, modified 12 parts of carried medicine sustained-release agent, 4 parts of mould proof auxiliary agent.
Modified carried medicine sustained-release agent is prepared by following technique：8 parts of lactic acid are warming up to 125 DEG C, absolute pressure by weight
1.2h is removed water under power 68Kpa, is then heated under 145 DEG C, absolute pressure 32Kpa, 1.5h is removed water, under nitrogen protection, 5 are added
Part stannous chloride is well mixed, and is warming up to 165 DEG C, is incubated 12min, then continues to be warming up to 182 DEG C, absolute pressure 5.5Kpa,
10.5h is incubated, acetone is then added, washed after precipitation, is dried in 45 DEG C to constant weight, is cooled to room temperature, 3 parts of collagens are then added
Albumen and 2.5 parts of dimethyl sulfoxide (DMSO)s are well mixed, and are stirred 35min in 1250r/min rotating speeds, are warming up to 21 DEG C, are incubated 18min,
3 parts of N are added, N- dicyclohexylcarbodiimides and 0.35 part of Enrofloxacin are well mixed, and 1.8h is stirred in 680r/min rotating speeds, cold
But obtain being modified carried medicine sustained-release agent to room temperature.
Mould proof auxiliary agent is prepared by following technique：By weight by 4 parts of calcium nitrate tetrahydrates, 12 parts of diammonium hydrogen phosphates and
12 parts of distilled water are well mixed, and then adjust pH to 10.1 with ammoniacal liquor, are then warming up to 88 DEG C, 28min are incubated, in 680r/min
Rotating speed stirs 2.5h, is cooled to room temperature, is subsequently added into 5 parts of dopamine hydrochlorides and is well mixed, at room temperature in 820r/min rotating speeds
4min is stirred, 4 parts of silver nitrates is then added and is well mixed, 3.5h is stirred in 1800r/min rotating speeds, washing, freeze-drying is obtained
Mould proof auxiliary agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross 120 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 12d in 75 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent, which are well mixed, obtains material C, material C then is concentrated to give into material A in 58 DEG C, then by material A in 95
DEG C dry 5h, be cooled to room temperature, the granular live pig getting fat disease-resistant feed of 25 mesh be made through comminutor.
Embodiment 5
A kind of live pig getting fat disease-resistant feed proposed by the present invention, its raw material includes by weight：42 parts of wheat flour, bean dregs 18
Part, 8 parts of rice bran, 3 parts of rape cake, 25 parts of wheat stalk, 5 parts of sweet potato vine, 7 parts of Microcystis aeruginosa, 4 parts of marine alga, 5 parts of dried silkworm chrysalis meal, fish meal 4
Part, 4.5 parts of oyster shell whiting, 15 parts of bone meal, 32 parts of oil cake of flax seed, 4 parts of kudzuvine root starch, 4 parts of tapioca starch, 5 parts of guar gum, 4 parts of konjac glucomannan, butter 3
Part, 5 parts of pleurotus eryngii bacterium, modified 8 parts of carried medicine sustained-release agent, 8 parts of mould proof auxiliary agent.
Modified carried medicine sustained-release agent is prepared by following technique：12 parts of lactic acid are warming up to 115 DEG C, absolute pressure by weight
0.8h is removed water under power 72Kpa, is then heated under 155 DEG C, absolute pressure 28Kpa, 2.5h is removed water, under nitrogen protection, 4 are added
Part stannous chloride is well mixed, and is warming up to 175 DEG C, is incubated 8min, then continues to be warming up to 188 DEG C, absolute pressure 4.5Kpa is protected
Warm 11.5h, then adds acetone, is washed after precipitation, is dried in 35 DEG C to constant weight, is cooled to room temperature, then adds 4 portions of collagen eggs
White and 1.5 parts of dimethyl sulfoxide (DMSO)s are well mixed, and are stirred 25min in 1350r/min rotating speeds, are warming up to 24 DEG C, are incubated 12min, plus
Enter 4 parts of N, N- dicyclohexylcarbodiimides and 0.25 part of Enrofloxacin are well mixed, and 1.2h, cooling are stirred in 820r/min rotating speeds
Obtain being modified carried medicine sustained-release agent to room temperature.
Mould proof auxiliary agent is prepared by following technique：By weight by 8 parts of calcium nitrate tetrahydrates, 8 parts of diammonium hydrogen phosphates and
18 parts of distilled water are well mixed, and then adjust pH to 9.9 with ammoniacal liquor, are then warming up to 92 DEG C, 22min are incubated, in 820r/min
Rotating speed stirs 1.5h, is cooled to room temperature, is subsequently added into 7 parts of dopamine hydrochlorides and is well mixed, at room temperature in 680r/min rotating speeds
8min is stirred, 2 parts of silver nitrates is then added and is well mixed, 2.5h is stirred in 2200r/min rotating speeds, washing, freeze-drying is obtained
Mould proof auxiliary agent.
A kind of preparation method of live pig getting fat disease-resistant feed of the present invention, comprises the following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal,
Oyster shell whiting, bone meal and butter co-grinding, then cross 180 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 18d in 65 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release are then added into filtrate
Agent and mould proof auxiliary agent, which are well mixed, obtains material C, material C then is concentrated to give into material A in 52 DEG C, then by material A in 100
DEG C dry 3h, be cooled to room temperature, the granular live pig getting fat disease-resistant feed of 35 mesh be made through comminutor.
Live pig getting fat disease-resistant feed in above-described embodiment 1- embodiments 5 is applied in actual raising, and control is set
Group, control group is the raising of normal diet, is obtained such as table 1 below data：
Table 1
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (8)
1. a kind of live pig getting fat disease-resistant feed, it is characterised in that its raw material includes by weight：25-45 parts of wheat flour, bean dregs
15-35 parts, 4-9 parts of rice bran, 2-5 parts of rape cake, 10-30 parts of wheat stalk, 4-9 parts of sweet potato vine, 2-8 parts of Microcystis aeruginosa, marine alga 2-
12 parts, 3-6 parts of dried silkworm chrysalis meal, 3-9 parts of fish meal, 3-5 parts of oyster shell whiting, 10-40 parts of bone meal, 15-35 parts of oil cake of flax seed, 3-9 parts of kudzuvine root starch, wood
2-5 parts of potato powder, 4-8 parts of guar gum, 2-5 parts of konjac glucomannan, 2-6 parts of butter, 1-6 parts of pleurotus eryngii bacterium, modified 5-15 parts of carried medicine sustained-release agent,
Mould proof auxiliary agent 3-9 parts.
2. live pig getting fat disease-resistant feed according to claim 1, it is characterised in that the raw material of modified carried medicine sustained-release agent is by weight
Amount part includes：5-15 parts of lactic acid, 3-6 parts of stannous chloride, 2-5 parts of collagen, 1-3 parts of dimethyl sulfoxide (DMSO), N, N- dicyclohexyls
2-5 parts of carbodiimide, 0.2-0.4 parts of Enrofloxacin.
3. live pig getting fat disease-resistant feed according to claim 1 or 2, it is characterised in that modified carried medicine sustained-release agent is by as follows
It is prepared by technique：Lactic acid is heated up, removes water, then heats up, is removed water, under nitrogen protection, stannous chloride is added and is well mixed,
Heating, insulation then continues to heating, and then insulation adds acetone, washed after precipitation, dry to constant weight, be cooled to room temperature, so
Add collagen and dimethyl sulfoxide (DMSO) afterwards well mixed, stir, heat up, insulation adds N, N- dicyclohexylcarbodiimides and
Enrofloxacin is well mixed, stirring, is cooled to room temperature and is obtained being modified carried medicine sustained-release agent.
4. the live pig getting fat disease-resistant feed according to claim any one of 1-3, it is characterised in that modified carried medicine sustained-release agent is pressed
It is prepared by following technique：Lactic acid is warming up under 110-130 DEG C, absolute pressure 65-75Kpa and removes water 0.5-1.5h, Ran Housheng
Temperature is to 140-160 DEG C, under absolute pressure 25-35Kpa, removes water 1-3h, under nitrogen protection, adds stannous chloride and is well mixed,
160-180 DEG C is warming up to, 5-15min is incubated, then continues to be warming up to 180-190 DEG C, absolute pressure 4-6Kpa is incubated 10-
12h, then adds acetone, after precipitation wash, in 30-50 DEG C dry to constant weight, be cooled to room temperature, then add collagen and
Dimethyl sulfoxide (DMSO) is well mixed, and 20-40min is stirred in 1200-1400r/min rotating speeds, is warming up to 20-25 DEG C, is incubated 10-
20min, adds N, and N- dicyclohexylcarbodiimides and Enrofloxacin are well mixed, and 1-2h is stirred in 650-850r/min rotating speeds,
Room temperature is cooled to obtain being modified carried medicine sustained-release agent.
5. the live pig getting fat disease-resistant feed according to claim any one of 1-4, it is characterised in that the raw material of mould proof auxiliary agent is pressed
Parts by weight include：3-9 parts of calcium nitrate tetrahydrate, 5-15 parts of diammonium hydrogen phosphate, 10-20 parts of distilled water, dopamine hydrochloride 4-8
Part, 1-5 parts of silver nitrate.
6. the live pig getting fat disease-resistant feed according to claim any one of 1-5, it is characterised in that mould proof auxiliary agent presses following work
It is prepared by skill：Calcium nitrate tetrahydrate, diammonium hydrogen phosphate and distilled water are well mixed, then pH is adjusted with ammoniacal liquor, then rises
Temperature, is incubated, and stirring is cooled to room temperature, is subsequently added into dopamine hydrochloride and is well mixed, stirs at room temperature, then add nitric acid
Silver is well mixed, stirs, and washing, freeze-drying obtains mould proof auxiliary agent.
7. the live pig getting fat disease-resistant feed according to claim any one of 1-6, it is characterised in that mould proof auxiliary agent presses following work
It is prepared by skill：Calcium nitrate tetrahydrate, diammonium hydrogen phosphate and distilled water are well mixed, then pH to 9.8- is adjusted with ammoniacal liquor
10.2,85-95 DEG C is then warming up to, 20-30min is incubated, 1-3h is stirred in 650-850r/min rotating speeds, is cooled to room temperature, connects
Addition dopamine hydrochloride to be well mixed, stir 3-9min in 650-850r/min rotating speeds at room temperature, then add silver nitrate
It is well mixed, 2-4h is stirred in 1500-2500r/min rotating speeds, washing, freeze-drying obtains mould proof auxiliary agent.
8. a kind of preparation method of live pig getting fat disease-resistant feed according to claim any one of 1-7, it is characterised in that bag
Include following steps：
S1, by wheat flour, bean dregs, rice bran, rape cake, wheat stalk, sweet potato vine, Microcystis aeruginosa, marine alga, dried silkworm chrysalis meal, fish meal, shell
Powder, bone meal and butter co-grinding, then cross 100-200 mesh sieve after material A, into material A add oil cake of flax seed, kudzuvine root starch and
Pleurotus eryngii bacterium, ferment 10-20d in 60-80 DEG C, is cooled to room temperature and obtains material B；
S2, material B filtered to take into filtrate, then added into filtrate tapioca starch, guar gum, konjac glucomannan, modified carried medicine sustained-release agent and
Mould proof auxiliary agent is well mixed to obtain material C, material C is then concentrated to give into material A in 50-60 DEG C, then by material A in 90-
105 DEG C of dry 2-6h, are cooled to room temperature, and the granular live pig getting fat disease-resistant feed of 20-40 mesh is made through comminutor.
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| CN107637721A (en) * | 2017-10-25 | 2018-01-30 | 明光市兴渔克氏原螯虾良种繁育中心 | A kind of Procambius clarkii cultivation disease-resistant feed |
| CN107772114A (en) * | 2017-10-26 | 2018-03-09 | 唐翔 | One boar food and preparation method thereof |
| CN108850435A (en) * | 2018-06-19 | 2018-11-23 | 宿松县春润食品有限公司 | A kind of mould proof feed of pig-breeding intumescent and preparation method thereof |
| CN108902492A (en) * | 2018-06-25 | 2018-11-30 | 彭奔 | A kind of live pig health getting fat feed and preparation method thereof |
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