CN107115099A - A kind of microcirculation of nail rugae imaging device - Google Patents
A kind of microcirculation of nail rugae imaging device Download PDFInfo
- Publication number
- CN107115099A CN107115099A CN201710195818.7A CN201710195818A CN107115099A CN 107115099 A CN107115099 A CN 107115099A CN 201710195818 A CN201710195818 A CN 201710195818A CN 107115099 A CN107115099 A CN 107115099A
- Authority
- CN
- China
- Prior art keywords
- microcirculation
- imaging
- light
- liquid lens
- light source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The invention discloses a kind of microcirculation of nail rugae imaging device, including device body and located at the intrinsic light source illuminating apparatus of described device, imaging receiver passage and image received device；Device body is provided with the finger clamp holder for being used for placing first folds in a garment to be seen；Light source illuminating apparatus emits beam and the light is projected into the first folds in a garment；Imaging receiver passage collects the light with microcirculation of nail rugae information, and the imaging of the light of collection is projected into described image reception device；The light with microcirculation of nail rugae information is to inject the light that the first folds in a garment epidermis is returned after the first folds in a garment is subcutaneously scattered；The imaging of the light of the image received device to receiving carries out opto-electronic conversion and analog-to-digital conversion, and the view data of acquisition is transmitted to computer progress image procossing, and shows the Microcirculatory Image of the first folds in a garment.The embodiment of the present invention reduces the volume of device and improves the observation convenience of microcirculation of nail rugae.
Description
Technical field
The present invention relates to medical instruments field, more particularly to a kind of microcirculation of nail rugae imaging device.
Background technology
Microcirculation typically refers to the less blood circulation of blood vessel diameter between arteriole and venule in human vas net, is
The most basic unit of blood circulation of human body.It is the important channel that blood carries out mass exchange with each cell tissue, microcirculation
Whether the physiological function that status representative each histoorgan of human body is normal.First folds in a garment is the skin wrinkle for being covered in nail root.Its
Epidermis is stratified squamous epithelium, the upper subcutaneous papilla for the formation of connective tissue projection, typically has a hair in each nipple
Thin blood vessel, moves towards epidermis, close to during epidermis with epidermis equality, it is easily visible under the microscope.Therefore, first folds in a garment is observation microcirculation
Good position, be also that Clinical Microcirculation checks the most frequently used position, doctor can according to observed Microcirculatory Image come
Judge the state of an illness of patient.
Existing microcirculation of nail rugae imaging system is mainly used based on the micro- of orthogonal polarization spectral imaging technology (OPS)
Imaging device is circulated, its imaging optical system uses refractive optical system, relatively satisfactory image can be obtained, in certain journey
Noninvasive, the real-time monitoring to microcirculation is realized on degree.But it is currently based on the microcirculation of nail rugae imaging dress of cross-polarization imaging
That puts still has its limitation：Above-mentioned imaging device is often bulky, not readily portable, when detecting Microcirculatory Image,
Need doctor's hand-held device handle or with other corollary equipment fixing devices, and need patient finger must be fixed when in use
Do not move, cause said apparatus to obtain the time length of Microcirculatory Image needs and prolonged stable figure can not be obtained
Picture.
The content of the invention
The technical problems to be solved by the invention are to overcome the deficiencies in the prior art to be imaged there is provided a kind of microcirculation of nail rugae
Device, can reduce the volume of device, and the carrying of convenient use person, improve the observation convenience of microcirculation of nail rugae.
In order to solve the above-mentioned technical problem, the embodiments of the invention provide a kind of microcirculation of nail rugae imaging device, including dress
Put body and located at the intrinsic light source illuminating apparatus of described device, imaging receiver passage and image received device；The dress
Put body and be provided with the finger clamp holder for being used for placing first folds in a garment to be seen；The light source illuminating apparatus emits beam and by the light
Line is projected to the first folds in a garment；The imaging receiver passage collects the light with microcirculation of nail rugae information, and by the light of collection
Imaging be projected to described image reception device；The light with microcirculation of nail rugae information is to inject the first folds in a garment subcutaneously to send out
The light of the first folds in a garment epidermis is returned after raw scattering；The imaging of the light of the described image reception device to receiving carries out light
Electricity conversion and analog-to-digital conversion, and the view data of acquisition is transmitted to computer, image procossing is carried out by the computer, and show
The Microcirculatory Image of the first folds in a garment is shown.
Compared with prior art, a kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention employs clamping knot
Structure, and optical imaging system is integrated in the structure of clamping shape.In use, need coated on the first folds in a garment of finger to be seen it is suitable
When cedar oil, then finger is positioned in the finger clamp holder of described device body on request, sends light source illuminating apparatus
Light be just projected to the first folds in a garment to be seen；The light that the light source illuminating apparatus is sent is applied through the first folds in a garment top layer
Cedar oil, injects the first folds in a garment subcutaneously, is scattered inside hypodermis；The light with microcirculation of nail rugae information is again
It is secondary to return to the first folds in a garment epidermis and inject the imaging receiver passage, described image reception device is finally imaged onto, through photoelectricity
Computer is passed to after conversion and analog-to-digital conversion and carries out image procossing, the Microcirculatory Image of the first folds in a garment is gone out by Computer display, is supplied
Doctor is observed.In the structure that optical imaging system is integrated in clamping shape, the microcirculation of nail rugae imaging device is reduced
Volume；And the microcirculation of nail rugae imaging device only needs to the device clamp finger to be seen i.e. on request when in use
Can, it is not necessary to which doctor is hand-held and can be fixed on quickly on the finger of user (patient), and the carrying of convenient use person is improved
The observation convenience of microcirculation of nail rugae.
Further, a piece of liquid lens are provided with the imaging receiver passage；Liquid is additionally provided with described device body
Eyeglass controller, the liquid lens controller is electrically connected with the liquid lens；The computer is always according to present image
The view data that reception device is obtained sends curvature adjust instruction to the liquid lens controller；The liquid lens controller
Adjust the curvature of the liquid lens in real time according to the curvature adjust instruction so that the image that described image reception device is obtained
Contrast reaches maximum.
It is used as the improvement project of foregoing invention embodiment, it is contemplated that microcirculation of nail rugae imaging device of the prior art is each
It is required for carrying out focusing by way of manual focusing finding picture rich in detail, as long as user slightly shakes, the picture of imaging system
Plane is just removed, and results in the need for manual focusing again, and system focusing time is long, uses highly inconvenient, and the present embodiment is carried
A kind of microcirculation of nail rugae imaging device supplied employs the technology of liquid lens automatic focusing.When described with microcirculation of nail rugae letter
The light of breath injects imaging receiver passage, and is imaged onto described image reception device by the liquid lens, through opto-electronic conversion
With computer is passed to after analog-to-digital conversion, computer is calculated according to currently received described image data by auto-focusing algorithm
Curvature adjust instruction quickly is sent to the liquid lens controller afterwards, the instruction indicates that the liquid lens controller changes institute
The curvature of liquid lens is stated, so as to adjust the focal length of the liquid lens, it is ensured that optical imaging system can focus real-time,
So that the picture contrast obtained in described image reception device reaches maximum, so as to show stable figure on computers
Picture or video.So, even if the finger of user is slightly shaken, liquid lens will also enter according to the curvature adjust instruction of computer
Row focusing real-time, is presented clearly Microcirculatory Image to defocused, realizes auto-focusing；Therefore the microcirculation of nail rugae imaging
Device is during image or video is obtained, and the hand of user can be moved everywhere, and the optical imaging system can be with people
The movement of hand and move, do not interfere with system imaging quality, and without manually focus, further increase that first folds in a garment is micro- to follow
The observation convenience of ring.And liquid lens compact conformation, compact, durability is good；Liquid in liquid lens is controlled by voltage
The Curvature varying of body carries out zoom, and zooming range is big, the penetration capacity of optical axis stable, light is strong, and machine is not present in focus process
Tool vibrates, and noise is small.
Further, if being provided with dry plate normal optical glass lens and a piece of liquid lens in the imaging receiver passage,
The liquid lens are located between the normal optical glass lens and described image reception device；Also set in described device body
There is liquid lens controller, the liquid lens controller is electrically connected with the liquid lens；The computer always according to work as
The view data that preceding image received device is obtained sends curvature adjust instruction to the liquid lens controller；The liquid lens
Controller adjusts the curvature of the liquid lens according to the curvature adjust instruction in real time so that described image reception device is obtained
Picture contrast reach maximum.
As the improvement project of foregoing invention embodiment, a kind of microcirculation of nail rugae imaging device that the present embodiment is provided into
If as being additionally provided with dry plate normal optical glass lens in receiving channel, because monolithic liquid lens can not obtain high-definition picture
And conjugation is in small distance, therefore carry out matched design to ensure whole light by normal optical glass lens and monolithic liquid lens
The image conjugation distance of imaging system is learned, and ensures the optical resolution of system.
Further, the imaging receiver passage includes first passage and second channel, the first passage and described the
Two passage vertical connections, the corner that the first passage is connected with the second channel is provided with reflecting prism, passes through described the
The light with microcirculation of nail rugae information that one passage is collected injects the second channel after being reflected through the reflecting prism；
The first passage is with being provided with least a piece of normal optical glass lens, the normal optical glass lens in the second channel
Including focusing eyeglass.
As the improvement project of foregoing invention embodiment, a kind of microcirculation of nail rugae imaging device that the present embodiment is provided into
Picture receiving channel uses right angle corner structure, and normal optical glass lens are mainly utilized in the first passage and focus mirror
Reflecting prism at piece, right angle corner, and eyeglass is focused in second channel so that described with microcirculation of nail rugae information
Light is sequentially passed through after the normal optical glass lens and the liquid lens, can be ultimately imaged described image and be received dress
In putting, and the imaging receiver passage using corner structure by optical imaging system when being integrated in device body, can be preferable
Utilization space, so as to reduce the volume of the microcirculation of nail rugae imaging device.
Further, one end of the imaging receiver passage is provided with opening, and the opening is located at the finger clamp holder
Top, the light with microcirculation of nail rugae information is incident upon the imaging receiver passage by the opening；The light source
Lighting device is in the imaging receiver passage and adjacent to the opening, and the light that the light source illuminating apparatus is sent passes through institute
State opening and be projected to the first folds in a garment.
As the improvement project of foregoing invention embodiment, a kind of microcirculation of nail rugae imaging device that the present embodiment is provided is by institute
The opening for stating imaging receiver passage is located at the finger clamp holder top, i.e., the top of described first folds in a garment to be seen, while will be described
Light source illuminating apparatus is in the imaging receiver passage and adjacent to the opening, so that the opening turns into whole optical imagery
The entrance of system, the light that the light source illuminating apparatus is sent is projected to the first folds in a garment by the opening, described to carry first folds in a garment
The light of microcirculation information injects the imaging receiver passage by the opening, and the route can avoid light in this process
It is middle to occur other transmittings or refraction and be weakened.
Further, glass is sealed provided with a flat board at the opening.
It is used as the improvement project of foregoing invention embodiment, it is contemplated that in use, the opening can be with being covered by cedar oil
First folds in a garment is in contact, and a kind of microcirculation of nail rugae imaging device that the present embodiment is provided at opening by setting the flat board to seal glass
Glass, can prevent cedar oil from flowing into the imaging receiver passage and the light source illuminating apparatus, it is to avoid to the imaging receiver
Passage pollutes or damaged the light source illuminating apparatus.
Further, the light source illuminating apparatus is included around the multiple LED for being open and being evenly arranged.
As the improvement project of foregoing invention embodiment, a kind of microcirculation of nail rugae imaging device that the present embodiment is provided passes through
Around the multiple LED that are evenly arranged of being open the light can be made to form uniform-illumination when being projected to the first folds in a garment
Region.
Further, the wavelength X that the light source illuminating apparatus emits beam meet hemoglobin in microcirculation of nail rugae and
The absorption spectrum of deoxyhemoglobin.
A kind of light of the microcirculation of nail rugae imaging device provided as the improvement project of foregoing invention embodiment, the present embodiment
Powered lighting arrangement sends the light that wavelength is λ and is projected to the first folds in a garment to be seen, and wavelength X meets blood red in microcirculation of nail rugae
The absorption spectrum of albumen and deoxyhemoglobin, such as in the absorption spectrum of hemoglobin and deoxyhemoglobin, 420nm is
The absworption peak of hemoglobin and deoxyhemoglobin etc., because the light of the wavelength is absorbed strongly by red blood cell, so on image
It was observed that capilary be rendered as dark pattern under bright background, more preferable imaging effect can be obtained.
Further, light source controller is additionally provided with described device body, the light source controller is illuminated with the light source
Device is electrically connected with；The computer is sent out always according to the frequency acquisition of described image reception device to the light source controller
Close control instruction；The light source controller controls the light source illuminating apparatus to realize and the figure according to the switching control instruction
As reception device gathers synchronous stroboscopic illumination.
As the improvement project of foregoing invention embodiment, a kind of microcirculation of nail rugae imaging device that the present embodiment is provided is used
The stroboscopic illumination light source synchronous with the collection of described image reception device；LED power consumption can be reduced using stroboscopic illumination, significantly
Reduce the degree of heat of light source illuminating apparatus；The stroboscopic light source synchronous with image received device can improve system to quick shifting
Dynamic object carries out high-resolution imaging, the smear that moving object is produced when reducing imaging.
Further, described image reception device is that charge coupled cell imaging sensor or CMOS are partly led
Body imaging sensor.
Brief description of the drawings
Fig. 1 is a kind of structural representation for microcirculation of nail rugae imaging device that present pre-ferred embodiments are provided；
Fig. 2 is a kind of liquid lens auto-focusing system for microcirculation of nail rugae imaging device that present pre-ferred embodiments are provided
System schematic diagram.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made
Embodiment, belongs to the scope of protection of the invention.
Referring to Fig. 1, it is a kind of structural representation for microcirculation of nail rugae imaging device that present pre-ferred embodiments are provided.
A kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention includes device body 1 and located at described device
Light source illuminating apparatus 2, imaging receiver passage 3 and image received device 4 in body 1；Described device body 1, which is provided with, to be used to put
Put the finger clamp holder 5 of first folds in a garment to be seen；The light source illuminating apparatus 2 emits beam and the light is projected into the first
Folds in a garment；The imaging receiver passage 3 collects the light with microcirculation of nail rugae information, and the imaging of the light of collection is projected into institute
State image received device 4；The light with microcirculation of nail rugae information is to inject after the first folds in a garment is subcutaneously scattered to return
The light of the first folds in a garment epidermis；The imaging for the light that 4 pairs of described image reception device is received carries out opto-electronic conversion and mould
Number conversion, and the view data of acquisition is transmitted to computer 6, image procossing is carried out by the computer 6, and show described
The Microcirculatory Image of first folds in a garment.
Wherein, if provided with dry plate normal optical glass lens (in the present embodiment including the in the imaging receiver passage 3
Certain focus lens 301, reflecting prism 302 and second focus eyeglass 303) and a piece of liquid lens 304, the liquid lens 304
Located at the normal optical glass lens (refer to second in the present embodiment and focus eyeglass 303) and described image reception device 4 it
Between；Liquid lens controller 7 (not illustrating in Fig. 1), the liquid lens controller 7 and institute are additionally provided with described device body 1
Liquid lens 304 are stated to be electrically connected with；The view data that the computer 6 is obtained always according to present image reception device 4 is to described
Liquid lens controller 7 sends curvature adjust instruction；The liquid lens controller 7 is adjusted in real time according to the curvature adjust instruction
The curvature R of the whole liquid lens 304 so that the picture contrast that described image reception device 4 is obtained reaches maximum.
Specifically, the imaging receiver passage 3 includes first passage 31 and second channel 32, the first passage 31 and institute
The vertical connection of second channel 32 is stated, the corner that the first passage 31 is connected with the second channel 32 is provided with reflecting prism
302, reflected by the light with microcirculation of nail rugae information described in the first passage 31 collection through the reflecting prism 302
After inject the second channel 32；The first passage 31 is with being provided with least a piece of normal optical glass in the second channel 32
Eyeglass, the normal optical glass lens include focusing eyeglass, determine in the present embodiment in the first passage 31 provided with first
In focus lens 301, the second channel 32 eyeglass 302 is focused provided with second.
One end of the imaging receiver passage 3 is provided with opening 33, and the opening 33 is located at the upper of the finger clamp holder 5
Portion, the light with microcirculation of nail rugae information is incident upon the imaging receiver passage 3 by the opening 33.The opening
At 33 glass 305 is sealed provided with a flat board.
The light source illuminating apparatus 2 is in the imaging receiver passage 3 and adjacent to the opening 33, the light source illumination
The light that device 2 is sent is projected to the first folds in a garment by the opening 33.The light source illuminating apparatus 2 includes surrounding the opening
The 33 multiple LED being evenly arranged.The wavelength X that the light source illuminating apparatus 2 emits beam meets the blood red egg in microcirculation of nail rugae
The absorption spectrum of white and deoxyhemoglobin.Light source controller 8 (not illustrating in Fig. 1) is additionally provided with described device body 1, it is described
Light source controller 8 is electrically connected with the light source illuminating apparatus 2；The adopting always according to described image reception device 4 of computer 6
Collection frequency sends switching control instruction to the light source controller 8；The light source controller 8 is according to the switching control instruction control
Make the realization of light source illuminating apparatus 2 and gather synchronous stroboscopic illumination with described image reception device 4.
Described image reception device 4 is charge coupled cell CCD image sensor or complementary metal oxide semiconductor figure
As sensor CMOS.
The operation principle of the embodiment of the present invention is described in detail below in conjunction with accompanying drawing：
A kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention is in use, need the first folds in a garment in finger to be seen
On coat appropriate cedar oil (as shown in Figure 1), then finger is positioned over to the finger clamp holder 5 of described device body 1 on request
Interior, the light for sending light source illuminating apparatus 2 is just projected on the first folds in a garment to be seen；Open stroboscopic light source light source illumination dress
2 and light source controller 8 and liquid lens controller 7 are put, the light source illuminating apparatus 2 sends wavelength and passes through institute for λ light
State opening 33 and its flat board sealing glass 305 is projected to the first folds in a garment, and the cedar oil applied through the first folds in a garment top layer, inject institute
State first folds in a garment subcutaneous, scattering occurs inside hypodermis (to be good light-scattering body under the micrometer depth of skin histology 100, observe
The scattering law of light, can effectively scattered light, scattering light is produced inside skin histology)；It is described to believe with microcirculation of nail rugae
The light of breath again returns to the first folds in a garment epidermis, and injecting the imaging by the opening 33 and its flat board sealing glass 305 connects
The first passage 31 of passage 3 is received, the light with microcirculation of nail rugae information first passes through described first and focuses eyeglass 301 to pass through again
The reflecting prism 302 enters the second channel 32 after reflecting, and then sequentially passes through second and focuses eyeglass 303 and liquid lens
304 are finally imaged onto in described image reception device 4 (opticpath is as shown in Figure 1), after opto-electronic conversion and analog-to-digital conversion
Pass to computer 6；The described image data of 6 pairs of receptions of computer carry out image procossing, show that the micro- of first folds in a garment follows
Ring image, while always according to currently received described image data, the liquid is quickly given after being calculated by auto-focusing algorithm
Eyeglass controller 7 sends curvature adjust instruction；The liquid lens controller 7 changes the liquid according to the curvature adjust instruction
The curvature R of somascope piece 304, so as to adjust the focal length of the liquid lens 304 so that obtained in described image reception device 4
Picture contrast reach maximum, stable image or video is shown on computer 6.
Wherein, a kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention employs clamp structure, and by optics
Imaging system is integrated in the volume that the microcirculation of nail rugae imaging device is reduced in the structure of clamping shape；And the first folds in a garment is micro- follows
Ring imaging device only needs to the device clamp finger to be seen on request when in use, it is not necessary to which doctor is hand-held and energy
Enough to be fixed on quickly on the finger of user (patient), the carrying of convenient use person improves the observation facility of microcirculation of nail rugae
Property.The microcirculation of nail rugae imaging device is when in use, it is necessary to which coating appropriate cedar oil on the first folds in a garment of finger to be seen is
In order to prevent the cuticula formation mirror effect of the first folds in a garment epidermis, produce strong reflection light and enter optical imaging system.
When measured object is skin histology, the cuticula of skin tissue surface is similar to minute surface, can be consumingly in accordance with the reflection law of light
Reflection light, because the intensity of the reflection light carries the intensity of the light of microcirculation of nail rugae information much larger than described in, therefore
If reflection light enters optical imaging system, the light with microcirculation of nail rugae information will be submerged, cause as unclear
It is clear.
A kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention additionally uses the skill of liquid lens automatic focusing
Art.Referring to Fig. 2, it is a kind of liquid lens auto-focusing for microcirculation of nail rugae imaging device that present pre-ferred embodiments are provided
Systematic schematic diagram.When the light with microcirculation of nail rugae information injects imaging receiver passage 3, and sequentially pass through first and focus
Eyeglass 301, reflecting prism 302, second focus eyeglass 303 (normal optical glass lens) and liquid lens 304 be imaged onto it is described
In image received device 4, computer 6 is passed to after opto-electronic conversion and analog-to-digital conversion, the computer 6 is always according to currently received
Described image data, quickly curvature adjust instruction is sent after being calculated by auto-focusing algorithm to the liquid lens controller 7,
The instruction indicates that the liquid lens controller 7 changes the curvature R of the liquid lens 304, so as to adjust the liquid lens
304 focal length, it is ensured that optical imaging system can focus real-time so that the figure obtained in described image reception device 4
Image contrast reaches maximum, so as to show stable image or video on computer 6.
The liquid lens 304 are using two kinds of liquid that can not be merged, and one of which is conductive aqueous solution, another
It is nonconducting oil.Both liquid are installed in small-sized tubular container, and the crescent moon quite with glass lens is formed in container
The curved surface of type, the curvature R of curved surface, which changes, causes the focal length of liquid lens 304 to change.The wettability effect of the water repellent surface of oil
Voltage can be used to change (therefore named electrowetting), make surface become more hydrophilic (moistening) or more water resistant.Due to original water resistant (or
It is hydrophilic) surface become now more absorb water (or water resistant), oil reservoir have to change its form, therefore, by adjusting in container two
The DC voltage at end, it is possible to change the curvature R on crescent surface at two kinds of different liquid junctions, that is, liquid lens
304 focal length.Liquid lens controller 7 is exactly to change its curvature R by changing the driving voltage of liquid lens 304, so that
Change its focal length.The corresponding different curvature R values of the different driving voltage of liquid lens 304, driving voltage is a total of N number of, therefore
The N number of R values (from R0, R1......RN) of correspondence, the curvature R changes for controlling liquid in liquid lens 304 by voltage carry out zoom,
Zooming range is big, the penetration capacity of optical axis stable, light is strong, and mechanical oscillation are not present in focus process, and noise is small.In addition, liquid
The compact conformation of somascope piece 304, compact, durability are good.
The computer 6 is when the contrast for detecting the nail fold micro-circulation images changes, to the liquid mirror
Piece controller 7 sends curvature adjustment control instruction, the liquid lens controller 7 is controlled the curvature R of the liquid lens 304
Gradually changed within the scope of one；In this process, the computer 6 constantly detects the contrast of the nail fold micro-circulation images
Degree, when finding highest contrast, sends curvature stability contorting to the liquid lens controller 7 and instructs, make the liquid
Eyeglass controller 7 controls the liquid lens 304 stable in the curvature R corresponding to the highest contrast.
However, it is to be understood that, the embodiment of above-mentioned use liquid lens technology of auto is intended only as the invention
More excellent embodiment, allow for microcirculation of nail rugae imaging device of the prior art and be required for every time by manual focusing
Mode carries out focusing and finds picture rich in detail, as long as user slightly shakes, and the image plane of imaging system is just removed, and results in the need for weight
New manual focusing, system focusing time is long, uses highly inconvenient.Therefore, by setting one in optical imaging systems
Piece can automatic focusing liquid lens 304, even if the finger of user is slightly shaken, liquid lens 304 also will be according to computer 6
Curvature adjust instruction focused real-time, to defocused presentation clearly Microcirculatory Image, realize auto-focusing；So that institute
Microcirculation of nail rugae imaging device is stated during image or video is obtained, the hand of user can be moved everywhere, the optics into
As system can be moved with the movement of human hand, system imaging quality is not interfered with, and without manually focusing, enter one
Step improves the observation convenience of microcirculation of nail rugae.In other embodiments, the optics of the microcirculation of nail rugae imaging device into
Normal optical glass lens are provided only with as system can also be used in other embodiments, such as described imaging receiver passage 3
Without the liquid lens 304, as long as the imaging receiver passage 3 can collect the light with microcirculation of nail rugae information simultaneously
The imaging for the light most collected at last is projected to described image reception device 4.
If being additionally provided with dry plate in a kind of imaging receiver passage 3 of microcirculation of nail rugae imaging device provided in an embodiment of the present invention
Normal optical glass lens, and the imaging receiver passage 3 uses right angle corner structure, normal optical glass lens, which are mainly, to be adopted
First in the first passage 31 focuses the reflecting prism 302 at eyeglass 301, right angle corner, and second channel 32
Interior second focuses eyeglass 303 so that the light with microcirculation of nail rugae information sequentially passes through above-mentioned normal optical glass
After eyeglass and the liquid lens 304, it can be ultimately imaged in described image reception device 4.
However, it is to be understood that, if above-mentioned set dry plate normal optical glass lens and adopt before the liquid lens 304
The embodiment set with the passage of right angle corner structure is intended only as the more excellent embodiment of the invention, is due to monolithic liquid
Eyeglass 304 can not obtain high-definition picture and conjugation is in small distance, therefore (i.e. first focuses by normal optical glass lens
Eyeglass 301, reflecting prism 302 and second focus eyeglass 303) carry out matched design to ensure entirely with monolithic liquid lens 304
The image conjugation distance of optical imaging system, and ensure the optical resolution of system；And the imaging receiver passage 3 utilizes turning
When structure allows the optical imaging system to be integrated in device body 1, can preferable utilization space, so as to reduce, the first folds in a garment is micro- to follow
The volume of ring imaging device.In other embodiments, the optical imaging system of the microcirculation of nail rugae imaging device can also be adopted
Other embodiments are used, such as the liquid lens 304 are provided only with described imaging receiver passage 3, or the imaging connects
Receive passage 3 and be not provided with right angle corner or provided with more right angle corners, or the first passage 31 in second channel 32 with being provided with
More normal optical glass lens.As long as the imaging receiver passage 3 can collect the light with microcirculation of nail rugae information
And the imaging for the light most collected at last is projected to described image reception device 4.
The opening 33 of the imaging receiver passage 3 is located at institute by a kind of microcirculation of nail rugae imaging device that the present embodiment is provided
State at the top of finger clamp holder 5, i.e., the top of described first folds in a garment to be seen, the opening 33 provided with flat board sealing glass 305.Together
When by the light source illuminating apparatus 2 in the imaging receiver passage 3 and the neighbouring opening 33, the light source illuminating apparatus
2 are included around the multiple LED that are evenly arranged of opening 33, and the ripples that emit beam of multiple LED of the light source illuminating apparatus 2
Long λ meets the absorption spectrum of the hemoglobin and deoxyhemoglobin in microcirculation of nail rugae, such as in hemoglobin and deoxidation blood
In the absorption spectrum of Lactoferrin, 420nm is the absworption peak of hemoglobin and deoxyhemoglobin etc..So that the opening 33 turns into
The entrance of whole optical imaging system, the light that the light source illuminating apparatus 2 is sent is projected to the first by the opening 33
Folds in a garment, the light with microcirculation of nail rugae information injects the imaging receiver passage 3 by the opening 33.
However, it is to be understood that, the embodiment of the structure setting of above-mentioned imaging receiver passage 3 and light source illuminating apparatus 2
The more excellent embodiment of the invention is intended only as, preferably imaging effect is provided to：The route can avoid light at this
During occur other transmitting or refraction and be weakened；It can make institute by the multiple LED being evenly arranged around the opening 33
State the region that a uniform-illumination is formed when light is projected to the first folds in a garment；Light source illuminating apparatus 2 send wavelength be λ light simultaneously
When being projected to the first folds in a garment to be seen, because the light of the wavelength is absorbed strongly by red blood cell, so that is observed on image is micro-
Blood vessel is rendered as the dark pattern under bright background, can obtain more preferable imaging effect；In addition, it is contemplated that in use, the opening
33 can be in contact with the first folds in a garment covered by cedar oil, by setting the flat board to seal glass 305 at opening 33, can prevent
Cedar oil flows into the imaging receiver passage 3 and the light source illuminating apparatus 2, it is to avoid the imaging receiver passage 3 is caused
Pollute or damage the light source illuminating apparatus 2.In other embodiments, the imaging receiver passage 3 and light source illuminating apparatus 2
Structure setting can also be using other embodiments.
A kind of microcirculation of nail rugae imaging device that the present embodiment is provided is employed gathers synchronous with described image reception device 4
Stroboscopic illumination light source；By the computer 6 according to the frequency acquisition of described image reception device 4 to the light source controller
8 send switching control instruction, and the instruction indicates that the light source controller 8 controls opening for multiple LED of the light source illuminating apparatus 2
Close, and frequency is identical with the frequency acquisition of described image reception device 4.
However, it is to be understood that, the embodiment of above-mentioned use stroboscopic illumination light source is intended only as the more excellent reality of the invention
Mode is applied, LED power consumption can be reduced using stroboscopic illumination, the degree of heat of light source illuminating apparatus 2 is greatly reduced；With image
The synchronous stroboscopic light source of reception device 4 can improve system and carry out high-resolution imaging to the object quickly moved, reduce imaging
When moving object produce smear.In other embodiments, the light source illuminating apparatus 2 can also be using other embodiment party
Formula, for example, do not use stroboscopic.
In summary, a kind of microcirculation of nail rugae imaging device provided in an embodiment of the present invention, by using the knot of clamping shape
The technology of structure and liquid lens automatic focusing improves the observation convenience of microcirculation of nail rugae.
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art
For, under the premise without departing from the principles of the invention, some improvement and deformation can also be made, these are improved and deformation is also considered as
Protection scope of the present invention.
Claims (10)
1. a kind of microcirculation of nail rugae imaging device, it is characterised in that including device body and intrinsic located at described device
Light source illuminating apparatus, imaging receiver passage and image received device；
Described device body is provided with the finger clamp holder for being used for placing first folds in a garment to be seen；
The light source illuminating apparatus emits beam and the light is projected into the first folds in a garment；
The imaging receiver passage collects the light with microcirculation of nail rugae information, and the imaging of the light of collection is projected into institute
State image received device；The light with microcirculation of nail rugae information is to inject after the first folds in a garment is subcutaneously scattered to return to institute
State the light of first folds in a garment epidermis；
Described image reception device carries out opto-electronic conversion and analog-to-digital conversion to the imaging of the light received, and by acquisition
View data is transmitted to computer, carries out image procossing by the computer, and show the Microcirculatory Image of the first folds in a garment.
2. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that set in the imaging receiver passage
There are a piece of liquid lens；
Liquid lens controller is additionally provided with described device body, the liquid lens controller electrically connects with the liquid lens
Connect；The view data that the computer is obtained always according to present image reception device sends curvature to the liquid lens controller
Adjust instruction；The liquid lens controller adjusts the curvature of the liquid lens according to the curvature adjust instruction in real time, makes
The picture contrast for obtaining the acquisition of described image reception device reaches maximum.
3. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that set in the imaging receiver passage
If having dry plate normal optical glass lens and a piece of liquid lens, the liquid lens located at the normal optical glass lens with
Between described image reception device；
Liquid lens controller is additionally provided with described device body, the liquid lens controller electrically connects with the liquid lens
Connect；The view data that the computer is obtained always according to present image reception device sends curvature to the liquid lens controller
Adjust instruction；The liquid lens controller adjusts the curvature of the liquid lens according to the curvature adjust instruction in real time, makes
The picture contrast for obtaining the acquisition of described image reception device reaches maximum.
4. a kind of microcirculation of nail rugae imaging device as claimed in claim 3, it is characterised in that the imaging receiver passage includes
First passage and second channel, the first passage and the second channel vertical connection, the first passage and described second
Passage connection corner be provided with reflecting prism, by the first passage collect described in carry microcirculation of nail rugae information light
Line injects the second channel after being reflected through the reflecting prism；The first passage is with being provided with least one in the second channel
Piece normal optical glass lens, the normal optical glass lens include focusing eyeglass.
5. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that the one of the imaging receiver passage
End is provided with opening, and the opening is located at the top of the finger clamp holder, and the light with microcirculation of nail rugae information passes through
The opening is incident upon the imaging receiver passage；The light source illuminating apparatus is in the imaging receiver passage and adjacent to institute
Opening is stated, the light that the light source illuminating apparatus is sent is projected to the first folds in a garment by the opening.
6. a kind of microcirculation of nail rugae imaging device as claimed in claim 5 a, it is characterised in that flat board is provided with the opening
Seal glass.
7. a kind of microcirculation of nail rugae imaging device as claimed in claim 5, it is characterised in that the light source illuminating apparatus includes
Around the multiple LED for being open and being evenly arranged.
8. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that the light source illuminating apparatus is sent
The wavelength X of light meets the absorption spectrum of the hemoglobin and deoxyhemoglobin in microcirculation of nail rugae.
9. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that be additionally provided with described device body
Light source controller, the light source controller is electrically connected with the light source illuminating apparatus；The computer is always according to described image
The frequency acquisition of reception device sends switching control instruction to the light source controller；The light source controller is according to the switch
Control instruction controls the light source illuminating apparatus to realize the stroboscopic illumination synchronous with the collection of described image reception device.
10. a kind of microcirculation of nail rugae imaging device as claimed in claim 1, it is characterised in that described image reception device is
Charge coupled cell imaging sensor or cmos image sensor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710195818.7A CN107115099A (en) | 2017-03-29 | 2017-03-29 | A kind of microcirculation of nail rugae imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710195818.7A CN107115099A (en) | 2017-03-29 | 2017-03-29 | A kind of microcirculation of nail rugae imaging device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107115099A true CN107115099A (en) | 2017-09-01 |
Family
ID=59718038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710195818.7A Pending CN107115099A (en) | 2017-03-29 | 2017-03-29 | A kind of microcirculation of nail rugae imaging device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107115099A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107961002A (en) * | 2017-11-11 | 2018-04-27 | 四川大学 | One kind is based on laser Doppler apparatus measurement microcirculation of nail rugae blood flow method |
| CN114401669A (en) * | 2019-07-24 | 2022-04-26 | 麻省理工学院 | Finger insert for a fold imaging device |
| US11963750B2 (en) | 2017-10-16 | 2024-04-23 | Massachusetts Institute Of Technology | Systems, devices and methods for non-invasive hematological measurements |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11299761A (en) * | 1998-04-21 | 1999-11-02 | Bisho Junkan Kenkyusho Kk | Observation device for capillary blood flow of eponychium of fingertip |
| CN201007780Y (en) * | 2007-01-10 | 2008-01-16 | 光亚国际股份有限公司 | Lens structure of nail twig blood microcirculation detecting machine |
| CN103622674A (en) * | 2013-11-15 | 2014-03-12 | 广州医软智能科技有限公司 | Minitype microcirculation imaging monitoring device and method |
| CN203828898U (en) * | 2013-12-06 | 2014-09-17 | 江西枫林光学仪器有限公司 | Microcirculation digital analyzer |
| CN104523221A (en) * | 2014-12-17 | 2015-04-22 | 严俊文 | Eye ground camera imaging system based on liquid lens focusing |
| CN104615975A (en) * | 2015-01-16 | 2015-05-13 | 深圳市维亿魄科技有限公司 | Mobile terminal and vein recognition device thereof |
| CN104856653A (en) * | 2015-06-12 | 2015-08-26 | 广州医软智能科技有限公司 | Device and method for detecting blood vessel |
| WO2016086023A1 (en) * | 2014-11-24 | 2016-06-02 | Massachusetts Institute Of Technology | Systems, apparatus, and methods for analyzing blood cell dynamics |
| CN205374279U (en) * | 2016-01-13 | 2016-07-06 | 湖南中医药大学 | Microcirculation of nail rugae mobile phone test micro lens |
-
2017
- 2017-03-29 CN CN201710195818.7A patent/CN107115099A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11299761A (en) * | 1998-04-21 | 1999-11-02 | Bisho Junkan Kenkyusho Kk | Observation device for capillary blood flow of eponychium of fingertip |
| CN201007780Y (en) * | 2007-01-10 | 2008-01-16 | 光亚国际股份有限公司 | Lens structure of nail twig blood microcirculation detecting machine |
| CN103622674A (en) * | 2013-11-15 | 2014-03-12 | 广州医软智能科技有限公司 | Minitype microcirculation imaging monitoring device and method |
| CN203828898U (en) * | 2013-12-06 | 2014-09-17 | 江西枫林光学仪器有限公司 | Microcirculation digital analyzer |
| WO2016086023A1 (en) * | 2014-11-24 | 2016-06-02 | Massachusetts Institute Of Technology | Systems, apparatus, and methods for analyzing blood cell dynamics |
| CN104523221A (en) * | 2014-12-17 | 2015-04-22 | 严俊文 | Eye ground camera imaging system based on liquid lens focusing |
| CN104615975A (en) * | 2015-01-16 | 2015-05-13 | 深圳市维亿魄科技有限公司 | Mobile terminal and vein recognition device thereof |
| CN104856653A (en) * | 2015-06-12 | 2015-08-26 | 广州医软智能科技有限公司 | Device and method for detecting blood vessel |
| CN205374279U (en) * | 2016-01-13 | 2016-07-06 | 湖南中医药大学 | Microcirculation of nail rugae mobile phone test micro lens |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11963750B2 (en) | 2017-10-16 | 2024-04-23 | Massachusetts Institute Of Technology | Systems, devices and methods for non-invasive hematological measurements |
| CN107961002A (en) * | 2017-11-11 | 2018-04-27 | 四川大学 | One kind is based on laser Doppler apparatus measurement microcirculation of nail rugae blood flow method |
| CN114401669A (en) * | 2019-07-24 | 2022-04-26 | 麻省理工学院 | Finger insert for a fold imaging device |
| CN114401669B (en) * | 2019-07-24 | 2023-01-17 | 麻省理工学院 | Finger insert for nail fold imaging device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107582020B (en) | A kind of ophthalmology imaging diagnosis system | |
| US7553020B2 (en) | Medical diagnostic instrument with variable focus liquid lens | |
| CN101116609B (en) | Scanning type automatic zooming iris image gathering system and gathering method thereof | |
| CN107115099A (en) | A kind of microcirculation of nail rugae imaging device | |
| US20100128117A1 (en) | Video infrared retinal image scanner | |
| CN102657516B (en) | Automatic retina imaging system | |
| CN102799878B (en) | Iris face fusion acquisition device | |
| CN103815869A (en) | Handheld type fundus camera | |
| CN106993117A (en) | A kind of auxiliary lens of Intelligent mobile equipment and illumination adjustment system | |
| CN210582453U (en) | Portable mydriasis-free eye fundus camera | |
| CN111035356A (en) | Automatic aligning and focusing eye ground or anterior segment imaging system and method | |
| CN106901712A (en) | A kind of microcirculation imaging device | |
| CN205795642U (en) | A kind of hand-held fundus camera | |
| CN210383874U (en) | Automatic alignment and positioning fundus camera | |
| CN205545531U (en) | Intelligent mobile device's auxiliary lens and illumination adjustment system | |
| CN108392173A (en) | Multispectral fundus imaging equipment | |
| CN208598368U (en) | Retina digital imaging system and retina digital imaging instrument | |
| CN207341749U (en) | A kind of microcirculation of nail rugae imaging device | |
| CN219439089U (en) | Blood vessel imaging device | |
| CN205903241U (en) | Novel fundus imaging system | |
| CN1307941C (en) | Eye image pickup device | |
| CN207575140U (en) | A kind of microcirculation imaging device | |
| CN109157188A (en) | More people position lenticule zoom OCT optical system and scan method | |
| CN210142334U (en) | Object recognition system | |
| CN213309634U (en) | Hand-held type eye ground camera of leading-in illumination light source of optic fibre |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170901 |
|
| RJ01 | Rejection of invention patent application after publication |