CN107106877A - 用于治疗uv诱发的皮肤屏障功能受损的局部用蝶芪组合物 - Google Patents

用于治疗uv诱发的皮肤屏障功能受损的局部用蝶芪组合物 Download PDF

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Publication number
CN107106877A
CN107106877A CN201580059094.2A CN201580059094A CN107106877A CN 107106877 A CN107106877 A CN 107106877A CN 201580059094 A CN201580059094 A CN 201580059094A CN 107106877 A CN107106877 A CN 107106877A
Authority
CN
China
Prior art keywords
pterostilbene
skin
topical
barrier function
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580059094.2A
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English (en)
Chinese (zh)
Inventor
小F·L·梅斯肯斯
R·W·德林杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CN107106877A publication Critical patent/CN107106877A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
CN201580059094.2A 2014-09-04 2015-09-03 用于治疗uv诱发的皮肤屏障功能受损的局部用蝶芪组合物 Pending CN107106877A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462046068P 2014-09-04 2014-09-04
US62/046,068 2014-09-04
PCT/US2015/048422 WO2016036999A1 (en) 2014-09-04 2015-09-03 Topical pterostilbene compositions for use in treating uv-induced loss of barrier function in skin

Publications (1)

Publication Number Publication Date
CN107106877A true CN107106877A (zh) 2017-08-29

Family

ID=55436471

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580059094.2A Pending CN107106877A (zh) 2014-09-04 2015-09-03 用于治疗uv诱发的皮肤屏障功能受损的局部用蝶芪组合物

Country Status (11)

Country Link
US (1) US9980924B2 (enExample)
EP (1) EP3194032B1 (enExample)
JP (1) JP2017525738A (enExample)
KR (1) KR20170045343A (enExample)
CN (1) CN107106877A (enExample)
AU (1) AU2015311799A1 (enExample)
BR (1) BR112017004304B1 (enExample)
CA (1) CA2959756C (enExample)
MX (1) MX375612B (enExample)
WO (1) WO2016036999A1 (enExample)
ZA (1) ZA201701510B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016036999A1 (en) 2014-09-04 2016-03-10 The Regents Of The University Of California Topical pterostilbene compositions for use in treating uv-induced loss of barrier function in skin
WO2018034328A1 (ja) * 2016-08-17 2018-02-22 香港友池有限公司 プテロスチルベン配糖体を含む外用組成物
JP7061766B2 (ja) * 2017-09-20 2022-05-02 学校法人同志社 Dj-1タンパク質産生促進用組成物
CN115209887A (zh) 2019-12-30 2022-10-18 罗丹菲尔茨有限责任公司 Ppar激动剂复合物及其使用方法
EP4029496A1 (en) * 2021-01-18 2022-07-20 Universitat de València Pterostilbene and silibinin for preventing, ameliorating or reducing radiation-induced diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2820975B1 (fr) * 2001-02-21 2004-03-12 Oreal Composition pour application topique comprenant au moins un hydroxystilbene et au moins un polyol pour solubiliser l'hydroxystilbene
US20090047309A1 (en) 2007-08-13 2009-02-19 Maes Daniel H Cosmetic methods and compositions for repairing human skin
US8703161B2 (en) 2007-08-13 2014-04-22 Elc Management, Llc Skin repair compositions comprising circadian gene activators and a synergistic combination of Sirt1 gene activators
US20100240767A1 (en) * 2009-03-23 2010-09-23 Muhammed Majeed Melanogenesis inhibitiuon by 3,5-dimethoxy-4'-hydroxystilbenes and cosmeceutical compositions thereof
EP2322159A1 (en) 2009-10-30 2011-05-18 Green Molecular, S.L. Use of pterostilbene (pter) as medicament for prevention and/or treatment of skin diseases, damages or injures or as cosmetic
US8841350B2 (en) * 2011-05-11 2014-09-23 ChromaDex Inc. Method for inducing UDP-glucuronosyltransferase activity using pterostilbene
JP2013075851A (ja) * 2011-09-30 2013-04-25 Fujifilm Corp 皮膚外用剤
US20130296440A1 (en) 2012-05-01 2013-11-07 ChromaDex Inc. Pterostilbene and curcumin combination for treatment of oxidative stress and inflammation
CN103239540B (zh) 2013-04-03 2014-11-12 广东药学院 一种凉血愈伤方提取物及治疗皮肤烧伤的复方白藜芦醇凉血愈伤油制剂
WO2016036999A1 (en) 2014-09-04 2016-03-10 The Regents Of The University Of California Topical pterostilbene compositions for use in treating uv-induced loss of barrier function in skin
WO2016037007A1 (en) 2014-09-04 2016-03-10 The Regents Of The University Of California Topical pterostilbene compositions for use in treating uv-induced skin damage and hyperplasia

Also Published As

Publication number Publication date
CA2959756C (en) 2023-02-28
BR112017004304B1 (pt) 2020-12-08
MX375612B (es) 2025-03-06
WO2016036999A1 (en) 2016-03-10
MX2017002818A (es) 2017-08-02
CA2959756A1 (en) 2016-03-10
AU2015311799A1 (en) 2017-03-30
JP2017525738A (ja) 2017-09-07
EP3194032A1 (en) 2017-07-26
US20160067194A1 (en) 2016-03-10
BR112017004304A2 (pt) 2017-12-05
US9980924B2 (en) 2018-05-29
EP3194032A4 (en) 2018-05-23
KR20170045343A (ko) 2017-04-26
EP3194032B1 (en) 2021-06-23
ZA201701510B (en) 2018-11-28

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Application publication date: 20170829