CN107106487A - 药物的眼部递送 - Google Patents

药物的眼部递送 Download PDF

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Publication number
CN107106487A
CN107106487A CN201580072370.9A CN201580072370A CN107106487A CN 107106487 A CN107106487 A CN 107106487A CN 201580072370 A CN201580072370 A CN 201580072370A CN 107106487 A CN107106487 A CN 107106487A
Authority
CN
China
Prior art keywords
substituted
composition
unsubstituted
present
unsubstituted alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580072370.9A
Other languages
English (en)
Chinese (zh)
Inventor
I·乌切格布
A·沙茨林
L·卡普雷托
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanomerics Ltd
Original Assignee
Nanomerics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanomerics Ltd filed Critical Nanomerics Ltd
Priority to CN202310406885.4A priority Critical patent/CN116392600A/zh
Publication of CN107106487A publication Critical patent/CN107106487A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580072370.9A 2014-11-03 2015-11-02 药物的眼部递送 Pending CN107106487A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310406885.4A CN116392600A (zh) 2014-11-03 2015-11-02 药物的眼部递送

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1419540.8A GB201419540D0 (en) 2014-11-03 2014-11-03 Delivery of drugs
GB1419540.8 2014-11-03
PCT/GB2015/053291 WO2016071677A1 (en) 2014-11-03 2015-11-02 Ocular delivery of drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202310406885.4A Division CN116392600A (zh) 2014-11-03 2015-11-02 药物的眼部递送

Publications (1)

Publication Number Publication Date
CN107106487A true CN107106487A (zh) 2017-08-29

Family

ID=52118610

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201580072370.9A Pending CN107106487A (zh) 2014-11-03 2015-11-02 药物的眼部递送
CN202310406885.4A Pending CN116392600A (zh) 2014-11-03 2015-11-02 药物的眼部递送

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202310406885.4A Pending CN116392600A (zh) 2014-11-03 2015-11-02 药物的眼部递送

Country Status (7)

Country Link
US (2) US10987304B2 (enExample)
EP (1) EP3215119B1 (enExample)
JP (1) JP6832276B2 (enExample)
CN (2) CN107106487A (enExample)
CA (1) CA2966592C (enExample)
GB (1) GB201419540D0 (enExample)
WO (1) WO2016071677A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112004524A (zh) * 2018-02-26 2020-11-27 耶路撒冷希伯来大学伊森姆研究发展有限公司 药物递送系统
CN116133690A (zh) * 2020-05-22 2023-05-16 纳诺莫里克斯有限公司 两亲性碳水化合物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2948134B1 (en) 2013-01-24 2020-03-04 Palvella Therapeutics, Inc. Compositions for transdermal delivery of mtor inhibitors
IL302385B2 (en) 2017-01-06 2024-06-01 Palvella Therapeutics Inc Non-aqueous preparations of mTOR inhibitors and methods of use
JP2021530463A (ja) 2018-07-02 2021-11-11 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物および使用方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004026912A1 (en) * 2002-09-20 2004-04-01 The University Of Strathclyde Solubilising polysaccharides substituted with hydrophilic and hydrophobic groups
WO2008017839A1 (en) * 2006-08-09 2008-02-14 The School Of Pharmacy, University Of London Polymeric micellar clusters and their uses in formulating drugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0938896A1 (en) * 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent
US6395756B2 (en) * 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent
DE10242080A1 (de) * 2002-09-11 2004-03-25 Degussa Ag Verfahren zur Katalysator-freien Herstellung von Cyanophenolen aus Methoxybenzonitrilen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004026912A1 (en) * 2002-09-20 2004-04-01 The University Of Strathclyde Solubilising polysaccharides substituted with hydrophilic and hydrophobic groups
WO2008017839A1 (en) * 2006-08-09 2008-02-14 The School Of Pharmacy, University Of London Polymeric micellar clusters and their uses in formulating drugs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ADELINE SIEW，等: "Enhanced Oral Absorption of Hydrophobic and Hydrophilic Drugs Using Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles", 《MOLECULAR PHARMACEUTICS》 *
刘松青，等: "《实用药物手册》", 31 October 2007, 四川大学出版社 *
赵晓亮，等: "壳聚糖胶束作为环孢素A眼部传递的载体", 《中国药科大学学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112004524A (zh) * 2018-02-26 2020-11-27 耶路撒冷希伯来大学伊森姆研究发展有限公司 药物递送系统
CN116133690A (zh) * 2020-05-22 2023-05-16 纳诺莫里克斯有限公司 两亲性碳水化合物

Also Published As

Publication number Publication date
US20170326064A1 (en) 2017-11-16
CN116392600A (zh) 2023-07-07
US20210212938A1 (en) 2021-07-15
CA2966592A1 (en) 2016-05-12
EP3215119B1 (en) 2021-03-10
US10987304B2 (en) 2021-04-27
WO2016071677A1 (en) 2016-05-12
GB201419540D0 (en) 2014-12-17
JP6832276B2 (ja) 2021-02-24
JP2017533228A (ja) 2017-11-09
EP3215119A1 (en) 2017-09-13
CA2966592C (en) 2023-03-07

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PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20170829

RJ01 Rejection of invention patent application after publication