CN107106191B - 宽聚焦的超声推进探头、系统和方法 - Google Patents
宽聚焦的超声推进探头、系统和方法 Download PDFInfo
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- CN107106191B CN107106191B CN201580061007.7A CN201580061007A CN107106191B CN 107106191 B CN107106191 B CN 107106191B CN 201580061007 A CN201580061007 A CN 201580061007A CN 107106191 B CN107106191 B CN 107106191B
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Clinical applications
- A61B8/0833—Clinical applications involving detecting or locating foreign bodies or organic structures
- A61B8/085—Clinical applications involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B17/225—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
- A61B17/2256—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves with means for locating or checking the concrement, e.g. X-ray apparatus, imaging means
- A61B17/2258—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves with means for locating or checking the concrement, e.g. X-ray apparatus, imaging means integrated in a central portion of the shock wave apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B2017/22005—Effects, e.g. on tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00505—Urinary tract
- A61B2018/00511—Kidney
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Vascular Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462065432P | 2014-10-17 | 2014-10-17 | |
| US62/065432 | 2014-10-17 | ||
| US201562160458P | 2015-05-12 | 2015-05-12 | |
| US62/160458 | 2015-05-12 | ||
| PCT/US2015/056261 WO2016061587A1 (en) | 2014-10-17 | 2015-10-19 | Broadly focused ultrasonic propulsion probes, systems, and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107106191A CN107106191A (zh) | 2017-08-29 |
| CN107106191B true CN107106191B (zh) | 2019-08-23 |
Family
ID=55747490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580061007.7A Active CN107106191B (zh) | 2014-10-17 | 2015-10-19 | 宽聚焦的超声推进探头、系统和方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10667831B2 (enExample) |
| EP (1) | EP3206597B1 (enExample) |
| JP (1) | JP6412275B2 (enExample) |
| CN (1) | CN107106191B (enExample) |
| WO (1) | WO2016061587A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200022714A1 (en) | 2016-10-18 | 2020-01-23 | SonoMotions Inc. | Ultrasound devices incorporating phase change materials and systems and methods using the devices |
| US11026706B1 (en) | 2016-11-18 | 2021-06-08 | University Of Washington | Modulation of transducer amplitude and phase distributions for controlled application of radiation force to an object |
| KR102059390B1 (ko) | 2018-03-30 | 2019-12-26 | 주식회사 에이치엔티메디칼 | 체외 충격파 쇄석기에 설치되는 초음파 거리 측정 장치 |
| US20210187330A1 (en) * | 2018-08-16 | 2021-06-24 | University Of Washington | Apparatus and method for ultrasound beam shaping |
| US12318635B2 (en) * | 2018-10-03 | 2025-06-03 | Mdsg Innovation Ltd. | Apparatus and method for treating kidneys |
| WO2020087049A1 (en) * | 2018-10-26 | 2020-04-30 | Applaud Medical, Inc. | Ultrasound device for use with synthetic cavitation nuclei |
| FR3119091B1 (fr) * | 2021-01-26 | 2024-03-29 | Edap Tms France | dispositif et procédé de caractérisation de l’évolution du profil de vitesse d’écoulement de fluide au niveau d’une zone de traitement par émission d’énergie |
| US12285636B2 (en) | 2021-08-05 | 2025-04-29 | The University Of Washington | Non-planar holographic beam shaping lenses for acoustics |
| CN119214660B (zh) * | 2024-11-12 | 2025-10-17 | 福州大学 | 基于最优视觉伺服的输尿管软镜手术机器人的肾结石自动追踪系统及方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103028203A (zh) * | 2011-10-09 | 2013-04-10 | 北京汇福康医疗技术有限公司 | 超声减脂治疗头及其工作方法 |
| CN103251438A (zh) * | 2012-02-15 | 2013-08-21 | 多尼尔医疗技术系统有限责任公司 | 冲击波治疗装置 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4132343C1 (enExample) * | 1991-09-27 | 1992-12-10 | Siemens Ag, 8000 Muenchen, De | |
| US5743862A (en) * | 1994-09-19 | 1998-04-28 | Kabushiki Kaisha Toshiba | Ultrasonic medical treatment apparatus |
| JP3993621B2 (ja) * | 1995-03-31 | 2007-10-17 | 株式会社東芝 | 超音波治療装置 |
| US5558092A (en) * | 1995-06-06 | 1996-09-24 | Imarx Pharmaceutical Corp. | Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously |
| US20010051131A1 (en) * | 1996-06-19 | 2001-12-13 | Evan C. Unger | Methods for delivering bioactive agents |
| US20030078227A1 (en) * | 1998-07-02 | 2003-04-24 | Greenleaf James F. | Site-directed transfection with ultrasound and cavitation nuclei |
| US7022077B2 (en) * | 2000-11-28 | 2006-04-04 | Allez Physionix Ltd. | Systems and methods for making noninvasive assessments of cardiac tissue and parameters |
| AU2003280416A1 (en) * | 2002-07-01 | 2004-01-19 | Allez Physionix | Systems and methods for making noninvasive assessments of cardiac tissue and parameters |
| US20050228284A1 (en) * | 2004-03-31 | 2005-10-13 | Charles Edward Baumgartner | System and method for power management in an ultrasound system |
| WO2006041058A1 (ja) * | 2004-10-15 | 2006-04-20 | Hitachi Medical Corporation | 超音波診断装置 |
| US7591996B2 (en) * | 2005-08-17 | 2009-09-22 | University Of Washington | Ultrasound target vessel occlusion using microbubbles |
| US7967763B2 (en) * | 2005-09-07 | 2011-06-28 | Cabochon Aesthetics, Inc. | Method for treating subcutaneous tissues |
| US10219815B2 (en) * | 2005-09-22 | 2019-03-05 | The Regents Of The University Of Michigan | Histotripsy for thrombolysis |
| US8057408B2 (en) * | 2005-09-22 | 2011-11-15 | The Regents Of The University Of Michigan | Pulsed cavitational ultrasound therapy |
| US8939911B2 (en) * | 2006-01-25 | 2015-01-27 | Kabushiki Kaisha Toshiba | Ultrasonic probe and apparatus for obtaining ultrasonic image |
| US7486405B2 (en) * | 2006-05-01 | 2009-02-03 | Hogan Josh N | Optimized reference level generation |
| US8535250B2 (en) * | 2006-10-13 | 2013-09-17 | University Of Washington Through Its Center For Commercialization | Method and apparatus to detect the fragmentation of kidney stones by measuring acoustic scatter |
| US20080195003A1 (en) * | 2007-02-08 | 2008-08-14 | Sliwa John W | High intensity focused ultrasound transducer with acoustic lens |
| US20080299177A1 (en) * | 2007-06-06 | 2008-12-04 | Biovaluation & Analysis, Inc. | Supramolecular Complexes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo |
| US20090230823A1 (en) * | 2008-03-13 | 2009-09-17 | Leonid Kushculey | Operation of patterned ultrasonic transducers |
| US9987505B2 (en) * | 2008-08-20 | 2018-06-05 | The Brigham And Women's Hospital, Inc. | Method for modifying glomerular permeability and function with focused ultrasound |
| US20100143241A1 (en) * | 2008-10-22 | 2010-06-10 | Johnson G Allan | Method and apparatus for delivery of agents across the blood brain barrier |
| EP2243561B1 (en) * | 2009-04-23 | 2018-11-28 | Esaote S.p.A. | Array of electroacoustic transducers and electronic probe for three-dimensional images comprising said transducer array |
| WO2011033277A2 (en) * | 2009-09-21 | 2011-03-24 | University Of Dundee | Apparatus and method for the manipulation of objects using ultrasound |
| JP5399192B2 (ja) * | 2009-09-30 | 2014-01-29 | 富士フイルム株式会社 | 超音波診断装置、および超音波診断装置の作動方法 |
| US8876740B2 (en) * | 2010-04-12 | 2014-11-04 | University Of Washington | Methods and systems for non-invasive treatment of tissue using high intensity focused ultrasound therapy |
| US9204859B2 (en) * | 2010-04-22 | 2015-12-08 | University Of Washington Through Its Center For Commercialization | Ultrasound based method and apparatus for stone detection and to facilitate clearance thereof |
| US9585631B2 (en) * | 2010-06-01 | 2017-03-07 | The Trustees Of Columbia University In The City Of New York | Devices, methods, and systems for measuring elastic properties of biological tissues using acoustic force |
| US8455989B2 (en) | 2011-07-01 | 2013-06-04 | Texas Instruments Incorporated | Package substrate having die pad with outer raised portion and interior recessed portion |
| US9096848B2 (en) * | 2011-11-10 | 2015-08-04 | Technion Research & Development Foundation Limited | Methods and devices for manipulation of target cells using a combined application of acoustical and optical radiations |
| US9241761B2 (en) * | 2011-12-28 | 2016-01-26 | Koninklijke Philips N.V. | Ablation probe with ultrasonic imaging capability |
| US9072879B2 (en) * | 2012-03-29 | 2015-07-07 | National Yang Ming University | Methods and system for ultrasound-mediated drug delivery |
| WO2014008408A1 (en) * | 2012-07-03 | 2014-01-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Method and apparatus to detect lipid contents in tissues using ultrasound |
| CA2878491A1 (en) * | 2012-07-08 | 2014-01-16 | Sunnybrook Health Sciences Centre | System and method for using ultrasound-stimulated microbubble exposures to induce ceramide accumulation in endothelial and tumor cells |
| WO2015070186A1 (en) * | 2013-11-08 | 2015-05-14 | The University Of North Carolina At Chapel Hill | Acoustic detection of activated phase-change contrast agent |
-
2015
- 2015-10-19 WO PCT/US2015/056261 patent/WO2016061587A1/en not_active Ceased
- 2015-10-19 US US15/519,821 patent/US10667831B2/en active Active
- 2015-10-19 JP JP2017539527A patent/JP6412275B2/ja active Active
- 2015-10-19 CN CN201580061007.7A patent/CN107106191B/zh active Active
- 2015-10-19 EP EP15851498.4A patent/EP3206597B1/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103028203A (zh) * | 2011-10-09 | 2013-04-10 | 北京汇福康医疗技术有限公司 | 超声减脂治疗头及其工作方法 |
| CN103251438A (zh) * | 2012-02-15 | 2013-08-21 | 多尼尔医疗技术系统有限责任公司 | 冲击波治疗装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107106191A (zh) | 2017-08-29 |
| US20170245874A1 (en) | 2017-08-31 |
| WO2016061587A1 (en) | 2016-04-21 |
| EP3206597B1 (en) | 2019-04-24 |
| US10667831B2 (en) | 2020-06-02 |
| EP3206597A1 (en) | 2017-08-23 |
| EP3206597A4 (en) | 2018-07-11 |
| JP2017532177A (ja) | 2017-11-02 |
| JP6412275B2 (ja) | 2018-10-24 |
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