CN107088042A - Endoscopic system - Google Patents
Endoscopic system Download PDFInfo
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- CN107088042A CN107088042A CN201710243197.5A CN201710243197A CN107088042A CN 107088042 A CN107088042 A CN 107088042A CN 201710243197 A CN201710243197 A CN 201710243197A CN 107088042 A CN107088042 A CN 107088042A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
- A61B1/000094—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope extracting biological structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4887—Locating particular structures in or on the body
- A61B5/489—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
Abstract
The present invention provides a kind of endoscopic system, and obtaining usual image, blood vessel with less frame number emphasizes image, oxygen saturation image.Centre wavelength 415nm blue narrow band light BN, centre wavelength 473nm oxygen saturation is irradiated successively to a corpse or other object for laboratory examination and chemical testing to determine light, G light, R light, and image successively.Blue arrowband view data BN, measure view data Bm, green image data G, red image data R are obtained by the shooting.Synthesis blueness arrowband view data BN obtains synthesis blue image data with view data Bm with measure.Usual image is made based on synthesis blue image data, green image data G, red image data R.The 1st arrowband image for highlighting superficial blood vessel is made based on blue arrowband view data BN, green image data G.Oxygen saturation image is made with view data Bm, green image data G, red image data R based on measure.
Description
The application be the applying date on 08 30th, 2013, Application No. 201310389260.8, entitled " inside peep
The divisional application of the application for a patent for invention of the adquisitiones of mirror system and endoscopic images ".
Technical field
The present invention relates to obtain the endoscopic system that white image, oxygen saturation image, blood vessel emphasize the image of image etc.
And the adquisitiones of endoscopic images.
Background technology
In medical field in recent years, widely use and possess the interior of light supply apparatus, endoscope apparatus and processor device
Endoscope system.In the diagnosis using the endoscopic system, the insertion section of endoscope is inserted into a corpse or other object for laboratory examination and chemical testing, while from its front end
The illumination light of portion's setted wavelength illuminates a corpse or other object for laboratory examination and chemical testing while shooting a corpse or other object for laboratory examination and chemical testing with the photographing element of leading section, thus obtains reflecting performance
The endoscopic images of various Biont informations on a corpse or other object for laboratory examination and chemical testing.
As endoscopic images, except white optical illumination for shooting a corpse or other object for laboratory examination and chemical testing visible ray as obtained from usual image with
Outside, also using by the narrow band light of the high wavelength domain of the absorptivity for illuminating a corpse or other object for laboratory examination and chemical testing hemoglobin to improve top layer blood
Pipe, the blood vessel of the contrast of mid-deep strata blood vessel are emphasized image and absorptivity by using oxyhemoglobin and reduced blood red
The arrowband optical illumination corpse or other object for laboratory examination and chemical testing in the different different absorbing wavelength domains of the absorptivity of albumen makes the visual oxygen of oxygen condition of blood vessel
Saturation degree image.This 3 kinds of images respectively have length respectively, by including 3 kinds of images in addition to the display of a kind of image simultaneously
In monitor, the diagnosis based on various viewpoints can be carried out.
This 3 kinds figures of image, oxygen saturation image are emphasized obtaining usual image, blood vessel successively using monochromatic photographing element
As in the case of, for usual image, it is necessary to which the illumination light of 3 frames part of rgb light, emphasizes image, it is necessary to top layer blood for blood vessel
The illumination light of 2 frames part for the green narrow band light that the blue narrow band light and mid-deep strata blood vessel that pipe is emphasized are emphasized, for oxygen saturation
Image is spent, it is necessary to the illumination light of 1~3 frame part including at least the illumination light in different absorbing wavelength domains.That is, in order to while obtaining 1
Usual image, the blood vessel of frame emphasize image, oxygen saturation image, and adding up to needs the illumination light of 6~8 frames.Therefore, to obtain simultaneously
To this 3 kinds of images, then frame rate (temporal resolution) can step-down.
In this regard, in TOHKEMY 2008-43604 publications, describing does not make frame rate extremely reduction ground while obtaining logical
The method that normal image and blood vessel emphasize this 2 kinds of images of image.According to JP 2008-43604 publications, by irradiating table successively
Blue narrow band light that layer blood vessel is emphasized, the green light in broadband, the illumination light of the red light in broadband this 3 frame part are imaged,
Obtain BN images, the G images in broadband, the R images of arrowband.Then, it is bright according to lifting is implemented to BN images on usual image
B images obtained from gain process of degree etc., G images, R images and generate, emphasize image on blood vessel, according to BN images and
G images are implemented to extract G obtained from the filtration treatment of mid-deep strata blood vessel*Image is generated.
Therefore, in the case where obtaining usual image successively and blood vessel emphasizing image, generally, it is necessary to the photograph of 5 frames part
Mingguang City, on the other hand, as JP 2008-43604 publications, by and with the image of gain process and filtration treatment etc.
Reason, can obtain image with the illumination light for 3 frames part for having lacked 2 frames.Thus, it is avoided that the reduction of frame rate.
But, in JP 2008-43604 publications, usual image is made due to applying gain process to BN images,
The another aspect of lightness is improved, also becomes to include more noise component(s).Therefore, the image quality of generally image is possible to bad
Change.Therefore, to obtain usual image, blood vessel simultaneously in the method using JP 2008-43604 publications and emphasize that image, oxygen are satisfied
In the case of degree image this 3 kinds of images, although the reduction of frame rate can be prevented, but there is the image quality of usual image can deteriorate this
The problem of sample.
The content of the invention
Present invention aims at there is provided the adquisitiones of a kind of endoscopic system and endoscopic images, can not make frame speed
Rate reduction ground obtains usual image, blood vessel with high image quality and emphasizes this 3 kinds of images of image, oxygen saturation image.
In order to reach above-mentioned purpose, endoscopic system of the invention is characterised by possessing：Lighting unit, its to a corpse or other object for laboratory examination and chemical testing according to
It is secondary to be radiated at the 1st illumination light of the 1st high wavelength domain of the absorptivity comprising blood hemoglobin in given wave band, comprising oxygen
Close absorptivity 2nd wavelength domain different from the absorptivity of reduced hemoglobin of hemoglobin the 2nd illumination light, comprising with
3rd illumination light of the 3rd different wavelength domain of the 1st and the 2nd wavelength domain and include 4th ripple different from the 1st to the 3rd wavelength domain
4th illumination light in long domain；Image information acquisition unit, it shoots a corpse or other object for laboratory examination and chemical testing successively by using monochromatic photographing element, with the 1st to the
4 illumination lights accordingly obtain the 1st to the 4th image information；Composograph information generating unit, it is to the 1st image information and the 2nd figure
The 1st composograph information is made as information progress synthesis processing；Usual image generating unit, it believes according to the 1st composograph
Breath, the 3rd image information, the 4th image information generate usual image；Arrowband image generating unit, it is generated according to the 1st image information
Arrowband image；Oxygen saturation image generating unit, it is made according to the 2nd image information makes the oxygen saturation figure of blood hemoglobin
The oxygen saturation image of pictureization.
It is preferred that the 1st and the 2nd wavelength domain is included in blue bands, the 3rd wavelength domain is included in green bands, the 4th ripple
Long domain is included in red band.It is preferred that the 1st and the 2nd wavelength domain is the arrowband of blueness, the 3rd wavelength domain is the broadband of green.
It is preferred that the 1st wavelength domain is 405~425nm, the 2nd wavelength domain is 450~500nm, and the 3rd wavelength domain is 480~620nm.
It is preferred that the 1st and the 2nd wavelength domain is the arrowband of blueness, the 3rd wavelength domain is the arrowband of green, and composograph information is made
Carry out synthesis processing to the 2nd image information and the 3rd image information to be made 2-in-1 into image information, usual image work into unit
Into unit be based on the 1st and the it is 2-in-1 into image information and the 4th image information be made usual image, to replace the 3rd image information,
Arrowband image generating unit is made arrowband image according to the 1st image information and the 3rd image information.It is preferred that the 1st wavelength domain is 405
~425nm, the 2nd wavelength domain is 450~500nm, and the 3rd wavelength domain is 530~550nm.It is preferred that oxygen saturation image generating unit
Oxygen saturation image is made according to the 2nd to the 4th image information.
It is preferred that the 1st wavelength domain is included in green bands, the 2nd and the 3rd wavelength domain is included in blue bands, the 4th ripple
Long domain is included in red band.It is preferred that the 1st wavelength domain is 530~550nm, the 2nd wavelength domain is 450~500nm, the 3rd wavelength
Domain is 380~520nm.It is included in the 1st wavelength domain in green bands, the 2nd and the 3rd wavelength domain is included in blue bands,
In the case that 4th wavelength domain is included in red band, preferably oxygen saturation image generating unit according to the 1st, the 2nd, the 4th image
Information is made oxygen saturation image.
The adquisitiones of the endoscopic images of the present invention is characterised by having：Illumination step, a corpse or other object for laboratory examination and chemical testing is radiated at successively to
1st illumination light of high the 1st wavelength domain of absorptivity comprising blood hemoglobin in fixed wave band, include oxyhemoglobin
Absorptivity 2nd wavelength domain different from the absorptivity of reduced hemoglobin the 2nd illumination light, comprising with the 1st and the 2nd
3rd illumination light of the 3rd different wavelength domain of wavelength domain and the 4th photograph comprising 4th wavelength domain different from the 1st to the 3rd wavelength domain
Mingguang City；Image information acquisition step, shoots a corpse or other object for laboratory examination and chemical testing, with the 1st to the 4th illumination light accordingly successively by using monochromatic photographing element
Obtain the 1st to the 4th image information；Composograph information is made step, and the 1st image information and the 2nd image information are synthesized
Handle to be made the 1st composograph information；Usual image is made step, by usual image generating unit according to the 1st composograph
Information, the 3rd image information, the 4th image information generate usual image；Arrowband image is made step, by arrowband image generating unit
Arrowband image is made according to the 1st image information；Oxygen saturation image is made step, by oxygen saturation image generating unit according to
2 image informations are made the oxygen saturation image for the oxygen saturation image conversion for making blood hemoglobin.
Invention effect
According to the present invention, due to the illumination light of 4 frames part with the 1st to the 4th illumination light be made usual image, arrowband image,
Oxygen saturation image, therefore the reduction of frame rate can be prevented.Further, since high to the absorptivity comprising blood hemoglobin
1st image information obtained from being shot under 1st illumination light of the 1st wavelength domain and absorptivity comprising oxyhemoglobin with
2nd image information obtained from being shot under 2nd illumination light of the 2nd different wavelength domain of the absorptivity of reduced hemoglobin is carried out
Synthesis is handled to obtain the 1st composograph information, and usual image, therefore generally figure are made based on the 1st composograph information
Picture is compared with the situation with gain process etc. to lift lightness, the image as the few high image quality of noise.
Brief description of the drawings
Fig. 1 is the skeleton diagram for the outward appearance for representing endoscopic system.
Fig. 2 is the block diagram for the Inner Constitution for representing endoscopic system.
Fig. 3 is the top view for the rotary filter for representing the 1st embodiment.
Fig. 4 is the chart for the transmission characteristic for representing each filter portion.
Fig. 5 is the chart for the extinction characteristic for representing hemoglobin.
Fig. 6 A are the explanation figures for the action for representing the photographing element in usual display pattern.
Fig. 6 B are the explanation figures for the action for representing the photographing element in the 1st special display pattern.
Fig. 6 C are the explanation figures for the action for representing the photographing element in the 2nd special display pattern.
Fig. 7 is the block diagram for the Inner Constitution for representing image processing part.
Fig. 8 is to represent to be made usual image, the 1st arrowband based on the view data obtained in 1 special display pattern
The explanation figure of image, the method for oxygen saturation image.
Fig. 9 is the explanation figure of the frequency filter for illustrating to apply green image data.
Figure 10 is the chart for the dependency relation for representing strength ratio B/G, R/G and oxygen saturation.
Figure 11 is the chart for the extinction characteristic for representing oxyhemoglobin and reduced hemoglobin.
Figure 12 is the explanation figure for representing to calculate the method for oxygen saturation from Figure 10 chart.
Figure 13 is the chart for representing oxygen saturation and the relation of gain.
Figure 14 is to be made usual image, the 2nd arrowband figure based on the view data obtained in 2 special display pattern
Picture, the explanation figure of the method for oxygen saturation image.
Figure 15 is the explanation figure of the frequency filter for illustrating to implement blue image data.
Figure 16 is the flow chart for a series of flow for representing the 1st special display pattern.
Figure 17 is while showing usual image, the 1st arrowband image, the image graph of the display device of oxygen saturation image.
Figure 18 is the top view for the rotary filter for representing the 2nd embodiment.
Figure 19 is to represent to be made usual image, the 3rd arrowband based on the view data obtained in 3 special display pattern
The explanation figure of image, the method for oxygen saturation image.
Embodiment
As shown in figure 1, the endoscopic system 10 of the 1st embodiment possesses：Produce illumination light light supply apparatus 11, while to
A corpse or other object for laboratory examination and chemical testing viewing area irradiation the illumination light from light supply apparatus 11 while shot endoscope apparatus 12, to being peeped from interior
The view data of lens device 12 carries out the processor device 13 of image procossing, display and passes through endoscope figure obtained from image procossing
The display device 14 of picture etc. and the input unit 15 being made up of keyboard etc..
In endoscope apparatus 12, bending section 17, bending section 18, observer front end have been set gradually from the side of operating portion 16
Portion 19.Bending section 17 can make its free bend due to flexibility.Bending section 18 is configured to by being configured at operating portion 16
Angulation knob (ア Application グ Le ノ Block) 16a rotation process and on 2 orthogonal directions free bend.Due to bending section can be made
18 correspond to position of subject etc. bends to any direction, any angle, accordingly, it is capable to make observer leading section 19 towards expectation
Look-out station.
Endoscopic system 10 possesses usual display pattern, the 1st special display pattern and the 2nd special display pattern, wherein, lead to
Normal display pattern display device 14 show by wave-length coverage from blueness to the subject picture of red visible ray constitute it is usual
Image；1st special display pattern shows usual image, the oxygen saturation image by blood hemoglobin simultaneously in display device 14
The oxygen saturation image of change, this 3 kinds of the 1st arrowband image figure for being highlighted by the narrow band light BN of blueness superficial blood vessel
Picture；2nd special display pattern shows usual image, oxygen saturation image, the narrow band light by green simultaneously in display device 14
GN and be highlighted the 2nd arrowband image of mid-deep strata blood vessel this 3 kinds of images.This 3 patterns can be by located at endoscope apparatus
12 switching switch 21 or input unit 15 is switched over.
As shown in Fig. 2 light supply apparatus 11 possesses：White light source 30, by the broadband light BB wavelength from the white light source 30
It is separated into the rotary filter 31 of the light of setted wavelength, is connected with the rotary shaft of rotary filter 31 and with certain rotary speed
Make the motor 32 that rotary filter 31 rotates, the displaced portions 34 for making rotary filter 31 be shifted on its radial direction.
White light source 30 possesses：Light source body 30a and aperture 30B.Light source body 30a is by xenon lamp, Halogen lamp LED, metal halogen
The light source in the broadband of compound lamp, White LED etc. is constituted, and sends broadband light BB.Broadband light BB has from blue bands to red
The wave-length coverage of the visible ray of frequency band, for example, the wave-length coverage with 400nm~700nm.Aperture 30B is by adjusting its aperture
To adjust the light quantity for the broadband light BB that rotary filter 31 is incided after the outgoing of white light source 30.
Endoscope apparatus 12 is fujinon electronic video endoscope, is possessed：By the light of 2 systems (2 lamps) guided from light guide 28,29 to
The Lighting Division 40 of viewing area irradiation；Shoot the image pickup part 41 of 1 system of viewing area；Detachably connect endoscope
The connector portion 50 of device 12 and light supply apparatus 11 and processor device 13.
Lighting Division 40 possesses 2 illuminating windows 43,44 located at the both sides of image pickup part 41, in the depths of each illuminating window 43,44
Light projector component 47,54 is stored respectively.Each light projector component 47,54 makes the light from light guide 28,29 by being irradiated after illuminating lens 51
To viewing area.Image pickup part 41 possesses receiving in the approximate centre position of observer leading section 19 from viewing area and by thing
1 observation window 42 of the reflected light of mirror component (diagram is omitted).
The light of the object lens component (diagram is omitted) for the picture light for being used to be taken into viewing area etc. is provided with the depths of observation window 42
System, and then in the depths of the object lens component provided with CCD (the ChaRGe Coupled Device, electric charge for shooting viewing area
Coupled apparatus) etc. photographing element 60.Photographing element 60 be not to each pixel set colour filter monochromatic photographing element, with by
Smooth surface (imaging surface) receives the light from object lens component, carries out light-to-current inversion to the light of receiving and exports image pickup signal (simulation letter
Number).In addition, as photographing element 60, using the CCD of IT (shifting (the ラ ィ Application ト ラ Application ス Off ア mono- of ィ Application タ mono-) in interior lines) type, but
In addition CMOS (ComplementaRy Metal-Oxide SemiconductoR, complementation with global shutter can also be used
Metal-oxide semiconductor (MOS)).
The image pickup signal exported from photographing element 60 by observer cable 67 is input to A/D converters 68.A/D is converted
Image pickup signal is transformed to view data (data signal) corresponding with its voltage level (voltage level) by device 68.Conversion
View data afterwards is input into processor device 13 via connector portion 50.Imaging control part 70 carries out taking the photograph for photographing element 60
As control.Shooting control is different by each display pattern.
Processor device 13 possesses：Control unit 71, image processing part 72 and storage part 74, connect in control unit 72 and show
Device 14 and input unit 15.Each portion in the control processor device 13 of control unit 72, and based on from endoscope apparatus 12
Switch the input information of switch 21 or the input of input unit 15 to control imaging control part 70 and the display of endoscope apparatus 12
The action of device 14.
As shown in figure 3, located at the rotary filter 31 of light supply apparatus 11 using the rotary shaft 31a that is connected with motor 32 as rotation
Turn center to be rotated.In rotary filter 31, successively along radial direction there is provided from the pivot for having rotary shaft 31a
1st, the 2nd, the 3rd filter areas 37,38,39.1st filter areas 37 is arranged on broadband light BB's in usual display pattern
In light path, the 2nd filter areas 38 is arranged in 1 special display pattern in broadband light BB light path, the 3rd filter area
Domain 39 is arranged in broadband light BB light path in 2 special display pattern.The switching of each filter areas 37~39, passes through
Rotary filter 31 is set to shift to carry out in the radial direction with displaced portions 34.
1st filter areas 37, is 120 in central angle.Sector region be respectively provided with B filters portion 37a, G optical filtering
Device portion 37b, R filter portion 37c.As shown in figure 4, B filters portion 37a makes blue bands (380~520nm) from broadband light BB
B light pass through, G filter portion 37b passes through the G light of green bands (480~620nm) from broadband light BB, R filters portion
37c passes through the R light of red band (580~720nm) from broadband light BB.Therefore, by the rotation of rotary filter 31 according to
Secondary outgoing B light, G light, R light.These B light, G light, R light after collector lens 48 and optical fiber 49 by inciding endoscope apparatus 12
Light guide 28,29.
2nd filter areas 38 sets superficial blood vessel to emphasize with wave filter portion 38a (for " superficial blood vessel is emphasized described in Fig. 3
With "), oxygen saturation measure filter portion 38b (mark is used to determine in Fig. 3 "), G filter portion 38c and R filters portion
38d.Superficial blood vessel emphasize with wave filter portion 38a make in broadband light BB have centre wavelength 415nm, wave-length coverage 405~
425nm blue narrow band light BN is passed through.The wave-length coverage of the blue narrow band light BN is in blue bands as shown in Figure 5
The high wavelength domain of the absorptivity of blood hemoglobin.Therefore, because by irradiating the blue narrow band light BN to a corpse or other object for laboratory examination and chemical testing, absorbing blue
Color narrow band light BN superficial blood vessel and do not absorb the blue narrow band light BN contrast of mucous membrane and uprise, therefore be highlighted top layer
Blood vessel.
In addition, oxygen saturation measure filter portion 38b makes closing in oxygen in broadband light BB, the extinction of reduced hemoglobin
Oxygen saturation in coefficient in the presence of the 450~500nm of wave-length coverage of poor (referring to Figure 11) determines light and passed through.To the blood of hypoxia
Extinction characteristic when pipe irradiation oxygen saturation determines light determines extinction during light with the blood vessel irradiation oxygen saturation to high oxygen condition
Characteristic is different.Therefore, by using the difference of the extinction characteristic, the oxygen saturation of blood hemoglobin can be determined.In addition, oxygen saturation
Degree determines light and centre wavelength preferably is set into 473nm.
In addition, G filter portion 38c, R filter portion 38d with above-mentioned G, R filter 37b, 37c due to having identical saturating
Characteristic is crossed, therefore, G, R filter portion 38c, 38d also make have wavelength domain G light same as described above, R in broadband light BB respectively
Light is passed through.According to the above, by the rotation of rotary filter 31, the blue narrow band light BN of outgoing, oxygen saturation determine light, G successively
Light, R light.The light of this 4 species by inciding light guide 28,29 successively after collector lens 48 and optical fiber 49.
B filters portion 39a, oxygen saturation measure filter portion 39b, mid-deep strata blood are provided with the 3rd filter areas 39
Pipe is emphasized with filter portion 39c (mark is emphasized to use for mid-deep strata blood vessel in Fig. 3 "), R filters portion 39d.Mid-deep strata blood vessel is strong
Filter portion 38c is called to make that there is centre wavelength 540nm, 530~550nm of wave-length coverage green narrow band light in broadband light BB
GN is passed through.The wave-length coverage of the green narrow band light GN is as shown in figure 5, be the absorptivity of the blood hemoglobin in green bands
High wavelength domain.Therefore, by the green narrow band light GN is irradiated to a corpse or other object for laboratory examination and chemical testing and absorb green narrow band light GN mid-deep strata blood vessel and
The contrast for not absorbing green narrow band light GN mucous membranes is uprised, therefore mid-deep strata blood vessel is highlighted.
In addition, B filters portion 39a, oxygen saturation measure have and B filters with filter portion 39b, R filter portion 39d
37a, oxygen saturation measure pass through characteristic with filter portion 38b, R filter portion 37c identicals.Therefore, these filter portions
39a, 39b, 39d make the B light with wavelength domain same as described above, oxygen saturation measure light, R light in broadband light BB saturating respectively
Cross.According to the above, by the rotation of rotary filter 31, outgoing B light, oxygen saturation determine light, green narrow band light GN, R successively
Light.The light of this 4 species is by collector lens 48 and optical fiber 49 and incides light guide 28,29 successively.
As described above, different light are irradiated to a corpse or other object for laboratory examination and chemical testing by each display pattern.For example, in usual display pattern, such as
Shown in Fig. 6 A like that, using the picture light of B, G, R three colors, viewing area is imaged successively with photographing element 60 and electricity is put aside
Lotus, the electric charge based on the savings is sequentially output blue signal Bc, green Gc, danger signal Rc.This series of action exists
It is set to during usual display pattern repeatedly.Then, by these blue signals Bc, green Gc, danger signal
Rc carries out A/D conversion, obtains blue image data Bc, green image data Gc, red image data Rc.
In the 1st special display pattern, as shown in Figure 6B, light, G light, R light are determined with blue narrow band light BN, oxygen saturation
Shoot the object of observation successively with photographing element 60, thus obtain blue narrow band signal BN, it is measure signal Bm, green G, red
Chrominance signal R.It is such to act during the 1st special display pattern is set as repeatedly.Then, by believing these blue arrowbands
Number BN, determine and carry out A/D conversion with signal Bm, green G, danger signal R, obtain blue arrowband view data BN, determine
With view data Bm, green image data G, red image data R.
In the 2nd special display pattern, as shown in Figure 6 C, light, green are determined to B light, oxygen saturation with photographing element 60
Narrow band light GN, R light is imaged successively, so as to obtain blue signal B, measure signal Bm, green narrow band signal GN, danger signal R.
It is such to act during the 2nd special display pattern is set as repeatedly.Then, by believing these blue signals B, measure
Number Bm, green narrow band signal GN, danger signal R carry out A/D, obtain blue image data B1, measure view data Bm, green
Arrowband view data GN, red image data R.
As described above, different view data, therefore the image procossing carried out by each pattern are obtained by each pattern
Also it is each different.As shown in fig. 7, image processing part 72 possesses：The view data obtained during based on usual display pattern is carried out
The view data that is obtained when the usual display pattern of image procossing is with image processing part 80, based on 1 special display pattern is entered
The view data obtained when 1st special display pattern of row image procossing is with image processing part 81, based on 2 special display pattern
To carry out the 2nd special display pattern image processing part 82 of image procossing.
Usual display pattern with image processing part 80 based on usual display pattern when obtain blue image data Bc, green
View data Gc, red image data Rc are made usual image.The blue image data Bc of the usual image being made is divided
The channel B of dispensing display device 14, green image data Gc is assigned to the G passages of display device 14, red image data R quilts
Distribute to the R passages of display device 14.
1st special display pattern image processing part 81 possesses：Usual image generating unit 84, the 1st arrowband image generating unit
85 and oxygen saturation image generating unit 86.In the 1st special use image processing part 81, as shown in figure 8, being made by usual image
Into portion 84 based on 1 special display pattern when obtained blue arrowband view data BN, measure view data Bm, green image
Data G, red image data R are made usual image, and blueness arrowband view data BN is based on by the 1st arrowband image generating unit 85
And green image data G is made the 1st arrowband image, it is based on using by using determining by oxygen saturation image generating unit 86
Oxygen saturation obtained from view data Bm, green image data G, red image data R computing is made oxygen saturation figure
Picture.
Usual 84 couples of blueness arrowband image BN of image generating unit and measure carry out synthesis processing with view data Bm, so that first
First it is made synthesis blue image data.Next, generally image generating unit 84 passes through pairing au bleu view data, green image
Data G and red image data G carries out synthesis processing to be made usual image.By the synthesis blue image in the usual image
Channel B of the data distribution to display device 14, green image data G distributes to the G passages of display device 14, red image data
R distributes to the R passages of display device 14.Thus, the visible ray of the corpse or other object for laboratory examination and chemical testing of full-color (full-color) is shown on usual image
Picture.
Here, synthesis blue image data due to be not as prior art (for example, JP 2008-43604 publications) that
Sample lifts lightness by gain process, but with the view data Bm of the measure with the information with identical blue bands
Synthesis handle and lift lightness.Thus, compared with prior art uses the situation of gain process like that, in synthesis blueness figure
As noise component(s) is few in data.In addition, the measure used in synthesis processing not only lifts the blueness of usual image with image
The image quality of component, is additionally operable to calculate oxygen saturation.Therefore, measure image plays 2 functions with 1 image.
1st arrowband image generating unit 85 to blue arrowband view data BN and green image data G by carrying out at synthesis
Reason, is made the 1st arrowband image for being highlighted superficial blood vessel.By by the blue arrowband view data in the 1st arrowband image
BN distributes to B, G passage of display device 14, and green image data G distributes to the R passages of display device 14, can be shown with pseudo- colour display screen
1st arrowband image of the image comprising superficial blood vessel is overall (superficial blood vessel is shown with the color of " dark brown " tone).In addition, in order to
The visual recognition of mid-deep strata blood vessel is improved in the 1st arrowband image, preferred pair green image data G is implemented as shown in Figure 9
Low~middle frequency frequency filter processing.So using low~middle frequency frequency filter processing be because mid-deep strata blood vessel with
Superficial blood vessel is compared to thicker.
Oxygen saturation image processing part 86 possesses：Strength ratio calculating section 86a, dependency relation storage part 86b, oxygen saturation are calculated
Go out portion 86c and image production part 86d.Strength ratio calculating section 86a asks for measure view data Bm and green image data G's
Strength ratio B/G and red image data R and green image data G strength ratio R/G.In strength ratio calculating section 86a, calculate
Go out the strength ratio between the pixel of same position between view data, in addition, whole pixels to view data calculate intensity
Than.Strength ratio is calculated alternatively, it is also possible to the pixel only to the vasculature part in view data.In this case, based on blood vessel portion
Point view data and the difference of view data of part beyond it determine vasculature part.
Dependency relation storage part 86b stores the dependency relation of strength ratio B/G and R/G and oxygen saturation.The dependency relation
As shown in Figure 10, stored with the two-dimentional sheet form for the contour that oxygen saturation is defined on two-dimensional space.The position of the contour,
Shape is obtained by the physical analogy of light scattering, is defined with correspondingly being changed with blood flow volume.In addition, strength ratio B/G,
R/G is stored in log engineer's scales form.
Above-mentioned dependency relation dissipates with oxyhemoglobin as shown in Figure 11, the extinction characteristic of reduced hemoglobin and light
Penetrate characteristic closely related.Here, curve 90 represents the absorptivity of oxyhemoglobin, curve 91 represents reduced hemoglobin
Absorptivity.For example, under the big wavelength of the difference of the such absorptivitys of 473nm, it is easy to obtain the information of oxygen saturation.But,
Measure comprising signal corresponding with 473nm light with view data Bm not only to oxygen saturation, also have to blood flow volume it is high according to
Lai Xing.Therefore, by except measure with view data Bm in addition to, also using according to the red that depends on blood flow volume and change
View data R2, blue image data B2 and reference picture (benchmark view data) as red image data R2 it is green
Strength ratio B/G and R/G obtained from color image data G2, can correctly ask for oxygen saturation independent of blood flow volume.
In addition, the light of 470~700nm wave-length coverages has, the scattering coefficient in mucosal tissue is small and wavelength dependency is small
Property.Thus, by the way that the light of the wave-length coverage is used as illumination light, the influence of the depth of blood vessel can be reduced, and can obtain
To the blood information comprising blood flow volume and the information of oxygen saturation.
Alternatively, it is also possible to also store the dependency relation of strength ratio R/G and blood flow volume in dependency relation storage part 86b.The phase
Pass relation as the bigger blood flow volumes of strength ratio R/G it is also bigger the dimensional table that is defined store.Strength ratio R/G and blood
The dependency relation of amount is used blood flow volume when calculating.
Oxygen saturation calculating section 86c is calculated using the dependency relation for being stored in dependency relation storage part 86b and by strength ratio
Strength ratio B/G, R/G that portion 86a is tried to achieve, to ask for the oxygen saturation in each pixel.In addition, in the following description, oxygen is satisfied
With degree calculate the middle measure used view data Bm, green image data G, red image data R given pixel it is bright
Angle value is set to B*、G*、R*.Accompany with this, strength ratio turns into B in each pixel*/G*、R*/G*。
Oxygen saturation calculating section 86c as shown in figure 12, according to the dependency relation for being stored in dependency relation storage part 86b, really
Fixed and strength ratio B*/G*、R*/G*Corresponding corresponding points P.Then, the contour of the boundary of oxygen saturation=0% is in corresponding points P
In the case of between the contour 89 of 88 and oxygen saturation=100% boundary, the percent value shown in corresponding points P is set to oxygen and satisfied
And degree.If for example, Figure 12 situation, then be located on 60% contour due to corresponding points P, therefore oxygen saturation turns into
60%.
On the other hand, in the case where corresponding points depart between contour 88 and contour 89, it is located in corresponding points contour
During 88 top of line, oxygen saturation is set to 0%, when corresponding points are located at below contour 89, oxygen saturation is set to 100%.
In addition, in the case where corresponding points depart between contour 88 and contour 89, oxygen saturation in the pixel can also be made
Reliability declines not appearing in display device 14.
Image production part 86d is used by the oxygen saturation calculating section 86c oxygen saturations calculated and by usual image generating unit
The 84 usual images being made, to generate the oxygen saturation image for making oxygen saturation image conversion.It is right in image production part 86d
The pixel value b of synthesis blue image data in usual image, green image data G pixel value g, red image data R
Pixel value r implements gain corresponding with oxygen saturation.
As shown in figure 12, in the case of high oxygen condition of the oxygen saturation for more than 60%, to pixel value b, g, r any
Person implements identical gain " 1 ".On the other hand, in the case of hypoxia of the oxygen saturation less than 60%, to pixel value b
Implement the gain of not enough " 1 ", on the other hand, the gain of " 1 " is performed more than to pixel value g, r.The usual image is implemented and oxygen
Image obtained from the corresponding gain of saturation degree turns into oxygen saturation image.By the pixel value b distribution in the oxygen saturation image
To the channel B of display device 14, pixel value g distributes to the G passages of display device 14, and pixel value r distributes to the R of display device 14
Passage.Thus, oxygen saturation image is in high oxygen condition, with whole with a corpse or other object for laboratory examination and chemical testing of the usual image identical color displays comprising blood vessel
Body, on the other hand, in hypoxia, shows vasculature part with the pseudo- colour display screen that cyan is adjusted.
As shown in fig. 7, the 2nd special display pattern image processing part 82 possesses：Usual image generating unit 94, the 2nd arrowband
Image generating unit 95 and oxygen saturation image generating unit 96.In the 2nd special display pattern with image processing part 82, such as scheme
Shown in 14, by usual image generating unit 94 based on 2 special display pattern when obtained blue image data B, measure image
Data Bm, green arrowband view data GN, red image data R are made usual image, by the base of the 2nd arrowband image generating unit 95
The 2nd arrowband image is made with view data Bm and green arrowband view data GN in measure, is made by oxygen saturation image
Portion 96 by using measure with view data Bm, green arrowband view data GN and red image data R computing based on being obtained
To oxygen saturation be made oxygen saturation image.
Usual 94 pairs of image generating unit is determined carries out synthesis processing with view data Bm and green arrowband view data GN, makees
Into synthesis green image data.Then, by entering to synthesis green image data with blue image data B, red image data R
Row synthesis is handled, and is made usual image.Blue image data B in the usual image is distributed to the channel B of display device 14,
Synthesis green image data distributes to the G passages of display device 14, and red image data R distributes to the R passages of display device 14.
Thus, the visible ray picture of a full-color corpse or other object for laboratory examination and chemical testing is shown on usual image.
Here, synthesis green image data is identical with synthesis blue image data, due to being lifted without using gain process
Lightness, but it is bright to be lifted with view data Bm synthesis processing with the measure with the information with identical green bands
Degree, therefore noise component(s) is few.In addition, the measure used in synthesis processing not only lifts the G components of usual image with image
Image quality, also used in calculating for oxygen saturation.Therefore, measure image plays 2 functions with 1 image.
2nd arrowband image generating unit 95 to blue image data B and green arrowband view data GN by carrying out at synthesis
Reason, is made the 2nd arrowband image for being highlighted mid-deep strata blood vessel.By by the blue image data B in the 2nd arrowband image
B, G passage of display device 14 are distributed to, green arrowband view data GN distributes to the R passages of display device 14, so that with puppet
Colour display screen shows that overall (mid-deep strata blood vessel is shown the 2nd arrowband image of the image comprising mid-deep strata blood vessel with the color of " cyan " tone
Show).In addition, the visual recognition in order to improve display blood vessel in the 2nd arrowband image, as shown in figure 15, preferred pair blue image
Data B implements high-frequency frequency filter processing.So handled using high-frequency frequency filter is because superficial blood vessel is with
Deep-level blood vessel is compared to thinner.
Oxygen saturation image generating unit 96 possesses：Strength ratio calculating section 96a, dependency relation storage part 96B, oxygen saturation are calculated
Go out portion 96c and image production part 96d.In strength ratio calculating section 96a, according to measure view data Bm and green arrowband figure
As data calculate strength ratio B/G, strength ratio R/G is calculated according to red image data R and green image data G.Then, based on this
Strength ratio B/G, the R/G calculated and the dependency relation for being stored in dependency relation storage part 96B, to calculate oxygen saturation.Here, phase
Pass relation storage part 96B dependency relation (dependency relation storage roughly the same with dependency relation storage part 86b dependency relation
In portion 96B dependency relation, the wavelength component of " G " of strength ratio turns into arrowband).
Then, image production part 96d uses the oxygen saturation calculated by oxygen saturation calculating section 96 and made by usual image
The usual image that is made into portion 94 generates oxygen saturation image.In image production part 96d, to the picture of blue image data
Plain value b, synthesis green image data G pixel value g, red image data R pixel value r implement increase corresponding with oxygen saturation
Benefit is managed.Gain process is identical with the processing carried out by image production part 96d (referring to Figure 13).Then, with image production part 86d
It is identical, the pixel value b after gain process is distributed to the channel B of display device 14, the pixel value g after gain process is distributed to
The G passages of display device 14, the pixel value r after gain process are distributed to the R passages of display device 14.Thus, in display dress
Putting 14 displays makes the oxygen saturation image of the pseudo- coloured silkization of the blood vessel of hypoxia.
Next, illustrating a series of flow in present embodiment along Figure 16 flow chart, especially with regard to the 1st
The a series of flow of special display pattern.In addition, on the 2nd special display pattern, due to also with the 1st special display pattern
Situation is identical, therefore omits the description.Under usual display pattern, by endoscope apparatus 12 be inserted into vivo, such as digest tube
It is interior.Observer leading section 19 is arranged on by desired look-out station by angulation knob 16a operation, generally observed.
In the usual observation, broadband light BB light path is arranged on the 1st filter areas 37.Thus, with B light, G light, R light successively according to
In a bright corpse or other object for laboratory examination and chemical testing, and colored usual image obtained from the display of display device 14 is shot with photographing element 60.
Then, in the case where look-out station is speculated as into lesion, cut by the switching switch 21 of endoscope apparatus 12
Change to the 1st special display pattern.By the pattern switching, broadband light BB light path is arranged on the 2nd filter areas 38.By
This, determines light, G light, R light from the blue narrow band light BN of the outgoing of rotary filter 31, oxygen saturation successively.By the light of outgoing successively according to
A corpse or other object for laboratory examination and chemical testing is penetrated, its reflection image is shot successively with photographing element 60.By the shooting, blue arrowband view data BN is obtained, determines and uses
View data Bm, green image data G, red image data R.
Then, synthesis blueness arrowband view data BN and measure are made synthesis blue image data with view data Bm,
The synthesis blue image data that is made based on this, green image data G, red image data R are made usual image.In addition,
The 1st arrowband image for highlighting superficial blood vessel is made based on blue arrowband view data BN and green image data G.In addition,
The oxygen condition image conversion that makes blood vessel is made with view data Bm, green image data G, red image data R based on measure
Oxygen saturation image.These usual images, the 1st arrowband image, oxygen saturation image 3 kinds of images as shown in Figure 17, it is horizontal
Shown simultaneously to arrangement.As long as the 1st special display pattern continues, a series of action of the above is just repeated.In addition, logical
Normal image, the 1st arrowband image, oxygen saturation image, can also at regular intervals 1 in addition to show as shown in Figure 17 simultaneously
Show individual 1 image of image.
As described above, scheme to almost obtain usual image, the 1st arrowband image, this 3 kinds of oxygen saturation image simultaneously
Picture, generally, this 3 frame of blue image data, green image data, red image data is needed in order to be made usual image
The image of part, the blue arrowband view data of 1 frame part is at least needed to be made the 1st arrowband image, in order to be made oxygen saturation
Spend image and need the measure view data of at least 1 frame part.That is, in order to simultaneously obtain/while show 3 kinds of images, minimum
Degree needs the view data of 5 frames part.
On the other hand, in the present invention, as the blue image of usual image, using the blue arrowband view data of synthesis and
Measure replaces blue image data with blue image data is synthesized obtained from view data.Thus, due to no longer needing indigo plant
The acquirement of color image data, therefore, compared with normal conditions, can be come with to have lacked 4 frames of 1 frame and meanwhile obtain usual image, it is the 1st narrow
Band image, oxygen saturation image.In addition, not being to lift indigo plant using with gain process etc. as the blue image of usual image
The image of the lightness of color arrowband view data, but improve lightness using with the synthesis processing with measure view data
Image, therefore high image quality and noise is few.
In addition, in above-mentioned 1st embodiment, in 1 special display pattern, acquirement is highlighted with blue narrow band light BN
1st arrowband image of superficial blood vessel, in 2 special display pattern, acquirement highlights mid-deep strata blood vessel with green narrow band light GN
The 2nd arrowband image, but in the 3rd special display pattern of the 2nd embodiment, obtain and use blueness narrow band light BN and green
Narrow band light GN highlights both the 3rd arrowband images of superficial blood vessel and mid-deep strata blood vessel.In 1st embodiment, substitution rotation
Filter 31 and use Figure 18 shown in rotary filter 100.Rotary filter 100 is centered on rotary shaft 100a, along straight
Footpath direction sets the 1st filter areas 37 and the 4th filter areas 101.1st filter areas 37 possesses and rotary filter 31
Identical B filters portion 37a, G filter portion 37b, R filter portion 37c.
4th filter areas 101 possesses：With being emphasized with superficial blood vessel with wave filter portion 38a identicals through characteristic
Superficial blood vessel is emphasized with wave filter portion 101a, with the oxygen that characteristic is passed through with oxygen saturation measure filter portion 38b identicals
Saturation degree measure with filter portion 101B, with mid-deep strata blood vessel emphasize with filter portion 39c identicals pass through characteristic in
Deep-level blood vessel is emphasized with filter portion 101c and special with being passed through with R filters portion 38d (or filter portion 39d) identical
The R filters portion 101d of property.Therefore, when broadband light BB is arranged on into 4 filter areas 101, rotary filter 100 is passed through
Rotate to irradiate blue narrow band light BN successively, oxygen saturation determines light, green narrow band light GN, R light.Then, by a corpse or other object for laboratory examination and chemical testing
Imaged when irradiating each illumination light, obtain blue arrowband view data BN, measure view data Bm, green arrowband picture number
According to GN, red image data R.
Then, as shown in figure 19, based on blue arrowband view data BN, measure view data Bm, green arrowband image
Data GN, red image data R are made usual image, based on blue arrowband view data BN and green arrowband view data
GN is made the 3rd arrowband image, for oxygen saturation image, based on by using measure view data Bm, green arrowband
Oxygen saturation obtained from view data GN, red image data R computing is made oxygen saturation image.
Here, when being made usual image, being synthesized to blue arrowband view data BN with measure with view data Bm
Processing is carried out at synthesis to be made synthesis blue image data to green arrowband view data GN and measure with view data Bm
Manage to be made synthesis green image data.Then, based on synthesis blue image data, synthesis green image data, red image
Data are made usual image.Because the blue image and green image of usual image are not to blue arrowband view data BN
And green arrowband view data GN has carried out image obtained from gain process, but add the conjunction of measure view data
Into image, therefore high image quality and noise is few.
In addition, the 3rd arrowband image is obtained by synthesizing blueness arrowband view data BN and green arrowband view data GN.
Blue arrowband view data BN in 3rd arrowband image is distributed to B, G passage of display device 14, green arrowband picture number
The R passages of display device 14 are distributed to according to GN.Thus, the 3rd arrowband image shows superficial blood vessel with the pseudo- colour display screen of " dark brown " tone, with
" cyan " tone puppet colour display screen shows mid-deep strata blood vessel.
The computing of oxygen saturation image, based on strength ratio B/ of the measure with view data Bm and green arrowband view data GN
G, red image data R are carried out with green arrowband view data GN strength ratio R/G.It is identical with the 1st embodiment, using strong
Degree calculates oxygen saturation than the dependency relation of B/G, R/G and oxygen saturation.Then, schemed by the synthesis blueness to usual image
Pixel value b, the pixel value g for synthesizing green image data, red image data R pixel value r as data implement to calculate with this
The corresponding gain of oxygen saturation, obtain oxygen saturation image.
In addition, in the above-described embodiment, only pseudo- coloured silk shows the blood vessel of hypoxia in oxygen saturation image, but
Can pseudo- colour display screen show that the corpse or other object for laboratory examination and chemical testing including the blood vessel comprising hypoxia is overall.In this case, the oxygen shape of blood vessel is preferably corresponded to
State, which predefines pseudo- color color, (such as, with the blood vessel of " red " display hyperoxia, with the reduction of oxygen saturation, makes the color of blood vessel
Gradually " band is blue ", show that oxygen saturation is less than the blood vessel of hypoxemia as 60% with " indigo plant ").
In addition, in the above-described embodiment, (being determined based on the view data from 3 wavelength part with view data Bm, green figure
As data G, red image data R) obtained strength ratio B/G, R/G carries out calculating for oxygen saturation, but it is also possible to take and generation
It, the strength ratio only obtained with the view data (determining with blue image data Bm, green image data G) according to 2 wavelength part
B/G carries out calculating for oxygen saturation.
In addition, in the above-described embodiment, using oxygen in blood flow volume (oxyhemoglobin and reduced hemoglobin sum)
Close hemoglobin proportion to be oxygen saturation to generate oxygen saturation image, but it is also possible to replace or on this basis,
Using the oxyhemoglobin index tried to achieve by " blood flow volume × oxygen saturation (%) ", by " blood flow volume × (100- oxygen saturations)
The reduced hemoglobin index that (%) " is tried to achieve.
Claims (14)
1. a kind of endoscopic system, it is characterised in that possess：
Lighting unit, the illumination light of the light comprising R, G, B regional is irradiated to a corpse or other object for laboratory examination and chemical testing；
Image information acquisition unit, image information is obtained according to reflected light of the illumination light in the corpse or other object for laboratory examination and chemical testing；
Narrow band light generation unit, is configured in the lighting unit, and generation constitutes the illumination light in the wave band of the illumination light
R, G, B at least one wave band among clip the wave band centre wavelength both sides two arrowbands light；With
Composograph information generating unit, based on by described image information acquisition unit according to the described anti-of more than two arrowbands
The more than two described image information penetrated light and obtained, to generate the 1st composograph information.
2. a kind of endoscopic system, it is characterised in that possess：
Lighting unit, the illumination light of the light comprising R, G, B regional is irradiated to a corpse or other object for laboratory examination and chemical testing；
Image information acquisition unit, image information is obtained according to reflected light of the illumination light in the corpse or other object for laboratory examination and chemical testing；
Narrow band light generation unit, is configured in the lighting unit, and generation constitutes the illumination light in the wave band of the illumination light
R, G, B at least one wave band among the maximum wavelength of the absorption characteristic comprising object of observation composition the 1st arrowband and with
The light of the 2nd different arrowband of 1st arrowband；With
Composograph information generating unit, based on by described image information acquisition unit according to the described anti-of more than two arrowbands
The more than two described image information penetrated light and obtained, to generate the 1st composograph information.
3. endoscopic system according to claim 2, it is characterised in that
The object of observation composition is hemoglobin.
4. endoscopic system according to any one of claim 1 to 3, it is characterised in that
The endoscopic system possesses：
Usual image generating unit, generation by described image information acquisition unit according to the narrow band light generation unit to comprising being given birth to
Into whole arrowbands the reflected light and that the multiple images information including the described image information that obtains is combined is logical
Normal image；With
Display unit, while display includes the multiple images of the usual image.
5. endoscopic system according to claim 1 or 2, it is characterised in that
The lighting unit is radiated at the absorptivity comprising blood hemoglobin is high in given wave band the 1st to a corpse or other object for laboratory examination and chemical testing successively
The 1st illumination light, the absorptivity comprising oxyhemoglobin of wavelength domain it is different from the absorptivity of reduced hemoglobin the 2nd
2nd illumination light of wavelength domain, the 3rd illumination light comprising 3rd wavelength domain different from the 1st wavelength domain and the 2nd wavelength domain, He Bao
The 4th illumination light containing 4th wavelength domain different from the 1st wavelength domain to the 3rd wavelength domain,
Described image information acquisition unit shoots the corpse or other object for laboratory examination and chemical testing successively by using monochromatic photographing element, with the 1st illumination light
The 1st image information to the 4th image information is accordingly obtained to the 4th illumination light,
The composograph information generating unit carries out synthesis processing to the 1st image information and the 2nd image information and come
The 1st composograph information is made,
The usual image generating unit is believed according to the 1st composograph information, the 3rd image information, the 4th image
The usual image of breath generation,
The endoscopic system is also equipped with lower unit：
Arrowband image generating unit, it generates arrowband image according to the 1st image information；And
Oxygen saturation image generating unit, it is made according to the 2nd image information makes the oxygen saturation figure of blood hemoglobin
The oxygen saturation image of pictureization.
6. endoscopic system according to claim 5, it is characterised in that
1st wavelength domain and the 2nd wavelength domain are included in blue bands, and the 3rd wavelength domain is included in green bands,
4th wavelength domain is included in red band.
7. endoscopic system according to claim 6, it is characterised in that
1st wavelength domain and the 2nd wavelength domain are the arrowbands of blueness, and the 3rd wavelength domain is the broadband of green.
8. endoscopic system according to claim 7, it is characterised in that
1st wavelength domain be 405~425nm, the 2nd wavelength domain be 450~500nm, the 3rd wavelength domain be 480~
620nm。
9. endoscopic system according to claim 6, it is characterised in that
1st wavelength domain and the 2nd wavelength domain are the arrowbands of blueness, and the 3rd wavelength domain is the arrowband of green,
The composograph information generating unit carries out synthesis processing to the 2nd image information and the 3rd image information and come
Be made it is 2-in-1 into image information,
It is described that the usual image generating unit is based on the 1st composograph information, the 4th image information and substitution
3rd image information described it is 2-in-1 be made the usual image into image information,
The arrowband image generating unit in addition to the 1st image information always according to the 3rd image information except making
Into arrowband image.
10. endoscopic system according to claim 9, it is characterised in that
1st wavelength domain be 405~425nm, the 2nd wavelength domain be 450~500nm, the 3rd wavelength domain be 530~
550nm。
11. endoscopic system according to claim 5, it is characterised in that
The oxygen saturation image generating unit is in addition to according to the 2nd image information always according to the 3rd image information
And the 4th image information be made the oxygen saturation image.
12. endoscopic system according to claim 5, it is characterised in that
1st wavelength domain is included in green bands, and the 2nd wavelength domain and the 3rd wavelength domain are included in blue bands,
4th wavelength domain is included in red band.
13. endoscopic system according to claim 12, it is characterised in that
1st wavelength domain be 530~550nm, the 2nd wavelength domain be 450~500nm, the 3rd wavelength domain be 380~
520nm。
14. endoscopic system according to claim 5, it is characterised in that
The oxygen saturation image generating unit is in addition to according to the 2nd image information always according to the 1st image information
And the 4th image information be made the oxygen saturation image.
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| CN110740678B (en) | 2017-06-13 | 2023-01-13 | 奥林巴斯株式会社 | Endoscope system and method for evaluating object |
| CN107625513B (en) * | 2017-09-30 | 2019-05-21 | 华中科技大学 | Enhancing display Narrow-Band Imaging endoscopic system and its imaging method |
| JP7147890B2 (en) * | 2021-02-04 | 2022-10-05 | ソニーグループ株式会社 | Information processing system, information processing method and program |
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Also Published As
| Publication number | Publication date |
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| CN107088042B (en) | 2021-02-05 |
| JP5715602B2 (en) | 2015-05-07 |
| CN103654688B (en) | 2017-04-26 |
| CN103654688A (en) | 2014-03-26 |
| JP2014050594A (en) | 2014-03-20 |
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