CN107080552B - A phantom for testing the imaging quality of various medical X-ray equipment and its system and method - Google Patents

A phantom for testing the imaging quality of various medical X-ray equipment and its system and method Download PDF

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CN107080552B
CN107080552B CN201710418930.2A CN201710418930A CN107080552B CN 107080552 B CN107080552 B CN 107080552B CN 201710418930 A CN201710418930 A CN 201710418930A CN 107080552 B CN107080552 B CN 107080552B
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张琛
孙勇
邱建峰
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Abstract

The invention discloses a phantom for testing imaging quality of various medical X-ray equipment, a system and a method thereof, wherein the phantom comprises two cube substrates, a reference module, a mammography module, a common radiography module and a computer tomography module are arranged on the cube substrates, and the reference module comprises a sphere and four metal bars; the mammography module comprises six cubes, seven metal balls and eight lines; the common X-ray photography module comprises twelve cylinders and six metal wire modules; the computer tomography module comprises six cylinders and a cylinder; the system comprises a gray level analysis, a spatial resolution analysis, a positioning and deformation analysis, a contrast analysis, a latitude analysis, a geometric distortion analysis and an active selection ROI analysis module. The invention can test the spatial resolution, contrast, linearity, geometric distortion, magnification, modulation transfer function and Z-axis spatial resolution of analog X-ray imaging, digital X-ray imaging, mammary X-ray imaging and CT imaging.

Description

一种测试多种医学X射线设备成像质量的体模及其系统、方法A phantom for testing the imaging quality of various medical X-ray equipment and its system and method

技术领域technical field

本发明属于模型模具领域,尤其涉及一种测试多种医学X射线设备成像质量的体模及其系统、方法。The invention belongs to the field of model moulds, in particular to a phantom for testing the imaging quality of various medical X-ray equipment, a system and a method thereof.

背景技术Background technique

随着社会的发展,X射线设备愈发普及,为医疗事业的发展提供了保障。但是利用X射线成像诊断病情的方法取决于图像的质量,而图像质量的维持需要各种X射线模态质量保证和质量检测。With the development of society, X-ray equipment is becoming more and more popular, which provides a guarantee for the development of medical care. However, the method of using X-ray imaging to diagnose diseases depends on the image quality, and the maintenance of image quality requires quality assurance and quality inspection of various X-ray modalities.

目前,用于执行质量保证(QA)测试的多种模态的特定体模价格昂贵,并且需要经过特定培训的人员进行相应操作才可获取图像质量的测试结果,无法达到一个体模测试多种模态X射线的目的,过程复杂且耗费大量时间、人力和物力,并且会因为检测人员培训程度不同或主观判断产生检测误差。At present, specific phantoms of multiple modalities used to perform quality assurance (QA) tests are expensive, and require specially trained personnel to perform corresponding operations to obtain image quality test results, which cannot achieve the purpose of testing multiple modal X-rays with one phantom.

综上所述,为了使得测试多种模态X射线成像质量更简便,如何设计一种测试多种X射线设备成像质量,且检测精度高,不依赖于主观判断的体模仍是待解决的技术问题。To sum up, in order to make it easier to test the quality of X-ray imaging of various modalities, how to design a phantom for testing the imaging quality of various X-ray equipment with high detection accuracy and independent of subjective judgment is still a technical problem to be solved.

发明内容Contents of the invention

为了克服上述现有技术的不足,本发明提供了一种测试多种医学X射线设备成像质量的体模及其系统、方法。In order to overcome the deficiencies of the above-mentioned prior art, the present invention provides a phantom for testing the imaging quality of various medical X-ray equipment and its system and method.

本发明所采用的技术方案是:The technical scheme adopted in the present invention is:

一种测试多种医学X射线设备成像质量的体模,包括两块正方体基材,所述正方体基材的四个角分别为棱圆角;每块正方体基材的一侧平面上分别设有大小不同的孔槽,所述两块正方体基材上的部分孔槽是成镜像分布,所述两块正方体基材通过设置在镜像分布孔槽内的模块相插接紧密贴合在一起;所述正方体基材的一侧平面上设置有基准模块、乳房X线摄影模块、普通X线摄影模块和计算机断层扫描模块,所述基准模块包括设置在正方体基材一侧平面中心处的圆球和四个设置在正方体基材一侧平面圆角圆心处的金属棒;所述乳房X线摄影模块包括六个圆形阵列平均分布在正方体基材一侧平面内圈的正方体、七个线性分布在圆球左侧的金属球和八个线性分布在圆球右侧的线条;所述普通X线摄影模块包括十二个圆形阵列平均分布在正方体基材一侧平面外围的圆柱体、六个线性分布在圆球上方的金属丝模块,每个金属丝模块的直径不同,所述金属丝模块由四根矩阵分布的直径相同的金属丝组成;所述计算机断层扫描模块包括十二个圆柱体中尺寸相同的六个圆柱体和以三十度角倾斜设置在正方体基材一侧平面上的圆柱;所述基准模块、乳房X线摄影模块、普通X线摄影模块和计算机断层扫描模块分别放置在所述正方体基材一侧平面上相应的孔槽内。A phantom for testing the imaging quality of a variety of medical X-ray equipment, comprising two cube substrates, the four corners of which are rounded corners; each cube substrate is provided with holes of different sizes on one side plane, and part of the holes on the two cube substrates are distributed in mirror images, and the two cube substrates are tightly fitted together by inserting modules arranged in the mirror distribution holes; one side plane of the cube substrate is provided with a reference module, a mammography module, an ordinary X-ray photography module and Computed tomography module, the reference module includes a ball arranged at the center of one side plane of the cube base material and four metal rods arranged at the center of the rounded corners of the side plane of the cube base material; the mammography module includes six circular arrays of cubes evenly distributed on the inner circle of the side plane of the cube base material, seven metal balls linearly distributed on the left side of the sphere, and eight lines linearly distributed on the right side of the sphere; Each wire module has a different diameter, and the wire module is composed of four metal wires distributed in a matrix with the same diameter; the computed tomography module includes six cylinders of the same size among the twelve cylinders and a cylinder inclined at an angle of 30 degrees on the plane on one side of the cube base material;

进一步的,所述正方体基材是由两块聚乙烯正方体重叠制成,其具体支撑各模块组件,并使得低密度模块组件成像明显的效果。Further, the cube base material is made of overlapping two polyethylene cubes, which specifically supports each module component and makes the low-density module component image obvious.

进一步的,所述圆球为碳钢钢球,且圆球的一半嵌入在正方体基材一侧平面中心处孔槽内,另一半悬空,其具体用于交叉线对中和零切片位置的评估的效果;所述四个金属棒分别为黄铜棒;所述四个金属棒的直径相同,且长度不同,其具体基准定位切片位置与深度,且用于检测CT的Z轴分辨率和3D重建的空间分辨率、并可以通过质心测算,计算图像的几何畸变和放大的效果。Further, the ball is a carbon steel ball, and half of the ball is embedded in the hole at the center of the plane on one side of the cube base material, and the other half is suspended in the air, which is specifically used for the evaluation of crossing line alignment and zero slice position; the four metal rods are respectively brass rods; the four metal rods have the same diameter and different lengths, and their specific reference positions slice position and depth, and are used to detect the Z-axis resolution of CT and the spatial resolution of 3D reconstruction.

进一步的,所述六个正方体的大小不同,且分别由尼龙材质制成,其具有测试乳腺X线摄影设备对低对比度组织的成像质量的效果;所述七个金属球的直径不同,所述七个金属球为碳钢钢珠,其具有模拟乳腺摄影微钙化的效果;所述八个线条的直径不同,且分别采用橡胶线,其具有模拟乳腺腺体及组织结构的效果。Further, the six cubes have different sizes and are made of nylon material respectively, which has the effect of testing the imaging quality of mammography equipment for low-contrast tissues; the diameters of the seven metal balls are different, and the seven metal balls are carbon steel balls, which have the effect of simulating microcalcification in mammography; the diameters of the eight lines are different, and rubber wires are used respectively, which has the effect of simulating mammary glands and tissue structure.

进一步的,所述十二个圆柱体的圆心连线是以圆球为圆心的圆环;所述十二个圆柱体中六个直径不同的圆柱体是由环氧树脂制成,其具有检测高、低对比度材料的成像效果的效果;所述四根金属丝之间的横纵间距与金属丝的直径相同,所述金属丝采用铜丝,用于检测成像的空间分辨率。Further, the line connecting the centers of the twelve cylinders is a circle centered on a sphere; among the twelve cylinders, six cylinders with different diameters are made of epoxy resin, which has the effect of detecting the imaging effect of high- and low-contrast materials; the horizontal and vertical distances between the four metal wires are the same as the diameter of the metal wires, and the metal wires are copper wires for detecting the spatial resolution of imaging.

进一步的,所述尺寸相同的六个圆柱体分别是由空气、泡桐、环氧树脂、尼龙以及ABS树脂制成;所述圆柱是由电木制成,其具有利用三角函数法检测计算机断层扫描设备扫描断面切片的厚度的效果。Further, the six cylinders with the same size are respectively made of air, paulownia, epoxy resin, nylon and ABS resin; the cylinder is made of bakelite, which has the effect of using trigonometric function method to detect the thickness of the section slice scanned by computer tomography equipment.

一种测试医学X线成像设备的体模的图像质量分析系统,包括灰度分析模块、空间分辨率分析模块、定位与变形分析模块、对比度分析模块、宽容度分析模块、几何畸变分析模块和主动选取ROI分析模块;An image quality analysis system for testing phantoms of medical X-ray imaging equipment, including a gray scale analysis module, a spatial resolution analysis module, a positioning and deformation analysis module, a contrast analysis module, a tolerance analysis module, a geometric distortion analysis module and an active ROI selection analysis module;

所述灰度分析模块,用于分析基准模块中十二个圆柱体、乳房X射线模块中六个正方体和八个线条的图像灰度,计算基准模块和乳房X射线模块灰度;The grayscale analysis module is used to analyze the image grayscale of twelve cylinders in the reference module, six cubes and eight lines in the mammogram module, and calculate the grayscale of the reference module and the mammogram module;

所述空间分辨率分析模块,用于分析普通X线摄影模块中八个金属丝模块,通过每个金属丝模块中金属丝横纵间距计算分辨率;The spatial resolution analysis module is used to analyze the eight wire modules in the common X-ray photography module, and calculates the resolution through the horizontal and vertical spacing of the wires in each wire module;

所述定位与变形分析模块,用于分析普通X线摄影模块中八个金属丝模块和四个金属棒,通过金属丝横纵间距差异计算空间位置和变形;The positioning and deformation analysis module is used to analyze the eight wire modules and four metal rods in the ordinary X-ray photography module, and calculate the spatial position and deformation through the difference in the horizontal and vertical spacing of the metal wires;

所述对比度分析模块,用于计算普通X线摄影模块中十二个圆柱体的高低对比度材质的成像效果;The contrast analysis module is used to calculate the imaging effects of the high and low contrast materials of the twelve cylinders in the common X-ray photography module;

所述宽容度分析模块,用于分析乳房X射线模块中七个金属球和八个线条,确定设备图像的显示宽容度;The latitude analysis module is used to analyze the seven metal balls and eight lines in the mammography module to determine the display latitude of the device image;

所述几何畸变分析模块,用于分析计算机断层扫描模块中圆柱,测试图像的几何畸变;The geometric distortion analysis module is used to analyze the geometric distortion of the cylinder in the computed tomography module and the test image;

所述主动选取ROI分析模块,用于自助选取ROI进行分辨率、线性度、对比度、几何畸变、空间分辨率、定位的图像测试;The active selection ROI analysis module is used to self-select ROI for image testing of resolution, linearity, contrast, geometric distortion, spatial resolution, and positioning;

一种测试医学X线成像设备的体模的工作方法,包括以下步骤:A working method for testing a phantom of medical X-ray imaging equipment, comprising the following steps:

(1)将体模放置在设备的检查床上,摆正体位,准备扫描;(1) Place the phantom on the examination bed of the equipment, adjust the body position, and prepare for scanning;

(2)调整设备的扫描视野,使扫描视野将体模完全覆盖,继续对体模进行扫描,得到相应的检查图像;(2) Adjust the scanning field of view of the equipment so that the scanning field of view completely covers the phantom, and continue to scan the phantom to obtain corresponding inspection images;

(3)将步骤(2)中得到的检查图像导入到图像质量分析系统中,在菜单中选择图像来源设备,选择需要检测的参数信息,点选进行分析;(3) Import the inspection image obtained in step (2) into the image quality analysis system, select the image source device in the menu, select the parameter information to be detected, and click to analyze;

(4)图像质量分析系统将自动分析图像数据结果,并与参数正常、成像标准的设备的图像数据进行对比,若参数浮动在一定范围内,则成像质量正常,否则,需要对设备进行调试。(4) The image quality analysis system will automatically analyze the image data results and compare them with the image data of equipment with normal parameters and imaging standards. If the parameters fluctuate within a certain range, the imaging quality is normal. Otherwise, the equipment needs to be debugged.

进一步的,所述步骤(1)中,设备为乳腺X线摄影、普通X线摄影或计算机断层扫描设备。Further, in the step (1), the equipment is mammography, general X-ray photography or computed tomography equipment.

进一步的,所述步骤(4)中,图像质量分析系统根据乳腺X线摄影和普通X线摄影扫描所得的图像灰度和分别率分析模拟X线成像、数字X线成像、乳腺X线成像、CR、DR、透视等平面X线设备图像的灰度、分辨率;图像质量分析系统根据计算机断层扫描设备扫描所得DICOM图像重建的3D模型、DICOM图像的灰度和DICOM图像的分辨率分析CT成像图像质量的空间分辨率、对比度、线性度、几何畸变、放大率、调制传递函数和Z轴空间分辨率。Further, in the step (4), the image quality analysis system analyzes the grayscale and resolution of images of plane X-ray equipment such as analog X-ray imaging, digital X-ray imaging, mammography, CR, DR, and perspective according to the image grayscale and resolution obtained by mammography and ordinary X-ray photography scanning; the image quality analysis system analyzes the spatial resolution, contrast, linearity, geometric distortion, and magnification of CT imaging image quality according to the 3D model reconstructed from the DICOM image obtained by scanning the computed tomography device, the grayscale of the DICOM image, and the resolution of the DICOM image. rate, modulation transfer function, and Z-axis spatial resolution.

与现有技术相比,本发明的有益效果是:Compared with prior art, the beneficial effect of the present invention is:

(1)采用正方体基材实现对各模块组件的支撑,并使得低密度模块组件成像明显;采用基准模块,实现交叉线对中和零切片位置的评估和基准定位切片位置与深度;采用乳腺X线摄影模块测试乳腺X线摄影设备对低对比度组织的成像质量、模拟乳腺腺体及组织结构;采用普通X线摄影模块检测高、低对比度材料的成像效果和平面成像中感光测定检查评估不同材料的灰度显示变化;采用计算机断层扫描模块测定计算机断层扫描设备的HU线性和感光;节约了成本,达到一种体模多种用途的目的,减少人员使用,保证测试成果与效率,节省时间,缓解机构部门的人力资源缺乏问题,保证图像质量的结果与分析;(1) Use a cube base material to support each module component, and make the imaging of low-density module components obvious; use a reference module to realize cross-line alignment and zero-slice position evaluation and benchmark positioning slice position and depth; use a mammography module to test the imaging quality of mammography equipment for low-contrast tissues, and simulate breast glands and tissue structures; use ordinary X-ray photography modules to detect imaging effects of high and low contrast materials and planar imaging. The HU linearity and light sensitivity of the layer scanning equipment; save costs, achieve the purpose of multiple uses of a phantom, reduce the use of personnel, ensure test results and efficiency, save time, alleviate the lack of human resources in institutional departments, and ensure the results and analysis of image quality;

(2)采用图像质量分析系统准确得测试结果,排除测试过程中,测试人员主观判断的失误,缩短测试时间。(2) Use the image quality analysis system to obtain accurate test results, eliminate the subjective judgment errors of testers during the test process, and shorten the test time.

附图说明Description of drawings

图1是本发明实施例的正方体基材的俯视图;Fig. 1 is the top view of the cube base material of the embodiment of the present invention;

图2是本发明实施例的普通X线摄影模块中十二个圆柱体的结构图;Fig. 2 is the structural diagram of twelve cylinders in the common X-ray photography module of the embodiment of the present invention;

图3是本发明实施例的基准模块和乳房X线摄影模块中六个正方体的结构图;Fig. 3 is a structural diagram of six cubes in the reference module and the mammography module of the embodiment of the present invention;

图4是本发明实施例的普通X线摄影模块中六个金属丝模块的结构图;Fig. 4 is the structural view of six wire modules in the common X-ray photography module of the embodiment of the present invention;

图5是本发明实施例的乳房X线摄影模块中七个金属球的结构图;Fig. 5 is the structural view of seven metal balls in the mammography module of the embodiment of the present invention;

图6是本发明实施例的乳房X线摄影模块中八个线条的结构图;Fig. 6 is a structure diagram of eight lines in the mammography module of the embodiment of the present invention;

其中,1、底面积直径为3mm*3mm的环氧树脂圆柱体,2、底面积直径为4mm*4mm的环氧树脂圆柱体,3、底面积直径为6mm*6mm的环氧树脂圆柱体,4、底面积直径为8mm*8mm的环氧树脂圆柱体,5、底面积直径为10mm*10mm的环氧树脂圆柱体,6、底面积直径为20mm*20mm的环氧树脂圆柱体,7、底面积直径为20mm*20mm的电木圆柱体,8、底面积直径为20mm*20mm的尼龙圆柱体,9、底面积直径为20mm*20mm的ABS树脂圆柱体,10、底面积直径为20mm*20mm的泡桐圆柱体,11、底面积直径为20mm*20mm的空气圆柱体,12、底面积直径为2mm*2mm的环氧树脂圆柱体,13、尺寸为2mm*2mm*2mm的尼龙正方体,14、底面积直径为3mm*8mm的黄铜圆柱体,15、尺寸为3mm*3mm*3mm的尼龙正方体,16、尺寸为4mm*4mm*4mm的尼龙正方体,17、底面积直径为3mm*12mm的黄铜圆柱体,18、底面积直径为2mm*20mm的倾斜电木圆柱体19、尺寸为6mm*6mm*6mm的尼龙正方体,20、尺寸为8mm*8mm*8mm的尼龙正方体,21、底面积直径为3mm*16mm的黄铜圆柱体,22、尺寸为10mm*10mm*10mm的尼龙正方体,23、底面积直径为3mm*20mm的黄铜圆柱体,24、直径为2mm的碳钢钢球,25、直径为0.1mm*1mm的铜丝模块,26、一组直径0.2mm*2mm的铜丝模块,27、一组直径0.3mm*3mm的铜丝模块,28、一组直径0.4mm*4mm的铜丝模块,29、一组直径0.5mm*5mm的铜丝模块,30、一组直径0.6mm*6mm的铜丝模块,31、直径为3mm的碳钢钢珠,32、直径为2mm的碳钢钢珠,33、直径为1.5mm的碳钢钢珠,34、直径为1mm的碳钢钢珠,35、直径为0.7mm的碳钢钢珠,36、直径为0.5mm的碳钢钢珠,37、直径为0.35mm的碳钢钢珠,38、截面直径为3mm*20mm的橡胶线,39、截面直径为2mm*20mm的橡胶线,40、截面直径为1.5mm*20mm的橡胶线,41、截面直径为1mm*20mm的橡胶线,42、截面直径为0.8mm*20mm的橡胶线,43、截面直径为0.6mm*20mm的橡胶线,44、截面直径为0.5mm*20mm的橡胶线,45、截面直径为0.4mm*20mm的橡胶线。Among them, 1. An epoxy resin cylinder with a bottom area diameter of 3mm*3mm; 2. An epoxy resin cylinder with a bottom area diameter of 4mm*4mm; 3. An epoxy resin cylinder with a bottom area diameter of 6mm*6mm; 4. An epoxy resin cylinder with a bottom area diameter of 8mm*8mm; 5. An epoxy resin cylinder with a bottom area diameter of 10mm*10mm; Bakelite cylinder, 8. Nylon cylinder with a bottom area diameter of 20mm*20mm, 9. ABS resin cylinder with a bottom area diameter of 20mm*20mm, 10. Paulownia cylinder with a bottom area diameter of 20mm*20mm, 11. Air cylinder with a bottom area diameter of 20mm*20mm, 12. Epoxy resin cylinder with a bottom area diameter of 2mm*2mm, 13. Nylon cube with a size of 2mm*2mm*2mm, 14. 15. A nylon cube with a size of 3mm*3mm*3mm; 16. A nylon cube with a size of 4mm*4mm*4mm; 17. A brass cylinder with a bottom area of 3mm*12mm in diameter; Nylon cube, 21. Brass cylinder with bottom area diameter of 3mm*16mm, 22. Nylon cube with size of 10mm*10mm*10mm, 23. Brass cylinder with bottom area diameter of 3mm*20mm, 24. Carbon steel ball with diameter of 2mm, 25. Copper wire module with diameter of 0.1mm*1mm, 26. A group of copper wire modules with diameter of 0.2mm*2mm, 27. A group of diameter of 0.3mm*3 mm copper wire module, 28, a set of copper wire modules with a diameter of 0.4mm*4mm, 29, a set of copper wire modules with a diameter of 0.5mm*5mm, 30, a set of copper wire modules with a diameter of 0.6mm*6mm, 31, a carbon steel ball with a diameter of 3mm, 32, a carbon steel ball with a diameter of 2mm, 33, a carbon steel ball with a diameter of 1.5mm, 34, a carbon steel ball with a diameter of 1mm, 35, a carbon steel ball with a diameter of 0.7mm Steel ball, 36. Carbon steel ball with a diameter of 0.5mm, 37. Carbon steel ball with a diameter of 0.35mm, 38. Rubber wire with a cross-sectional diameter of 3mm*20mm, 39. Rubber wire with a cross-sectional diameter of 2mm*20mm, 40. Rubber wire with a cross-sectional diameter of 1.5mm*20mm, 41. Rubber wire with a cross-sectional diameter of 1mm*20mm, 42. Rubber wire with a cross-sectional diameter of 0.8mm*20mm, 43. 0.6mm*20mm rubber thread, 44. Rubber thread with a cross-sectional diameter of 0.5mm*20mm, 45. Rubber thread with a cross-sectional diameter of 0.4mm*20mm.

具体实施方式Detailed ways

应该指出,以下详细说明都是例示性的,旨在对本申请提供进一步的说明。除非另有指明,本文使用的所有技术和科学术语具有与本申请所属技术领域的普通技术人员通常理解的相同含义。It should be pointed out that the following detailed description is exemplary and intended to provide further explanation to the present application. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.

需要注意的是,这里所使用的术语仅是为了描述具体实施方式,而非意图限制根据本申请的示例性实施方式。如在这里所使用的,除非上下文另外明确指出,否则单数形式也意图包括复数形式,此外,还应当理解的是,当在本说明书中使用术语“包含”和/或“包括”时,其指明存在特征、步骤、操作、器件、组件和/或它们的组合。It should be noted that the terminology used here is only for describing specific implementations, and is not intended to limit the exemplary implementations according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should also be understood that when the terms "comprising" and/or "comprises" are used in this specification, they indicate the presence of features, steps, operations, means, components and/or combinations thereof.

本申请的一种典型的实施方式中,如图1所示,提供了一种测试多种医学X射线设备成像质量的体模,包括两块正方体基材,正方体基材的四个角分别为棱圆角,每块正方体基材的一侧平面上分别设有大小不同的孔槽,两块正方体基材的部分孔槽是成镜像分布;两块正方体基材通过设置在镜像分布孔槽内的模块相插接紧密贴合在一起;正方体基材是由两块聚乙烯正方体重叠制成,其产生的有益效果为:支撑各模块组件,并使得低密度模块组件成像明显;基材仿真类似厚度的人体软组织,并可用于检测X线成像的均匀度。In a typical implementation of the present application, as shown in Figure 1, a phantom for testing the imaging quality of various medical X-ray equipment is provided, which includes two cube substrates, the four corners of which are rounded corners, and holes of different sizes are respectively arranged on one side plane of each cube substrate, and part of the holes of the two cube substrates are distributed in a mirror image; The beneficial effects produced are: supporting each module component, and making the imaging of the low-density module component obvious; the base material simulates human body soft tissue with similar thickness, and can be used to detect the uniformity of X-ray imaging.

正方体基材的一侧平面上设置有基准模块、乳房X线摄影模块、普通X线摄影模块和计算机断层扫描模块;所述基准模块、乳房X线摄影模块、普通X线摄影模块和计算机断层扫描模块分别放置在正方体基材一侧平面上相应的孔槽内。One side plane of the cube substrate is provided with a reference module, a mammography module, a common X-ray photography module and a computed tomography module; the reference module, the mammography module, the common X-ray photography module and the computed tomography module are respectively placed in corresponding slots on one side plane of the cube substrate.

如图3所示,基准模块包括设置在正方体基材一侧平面中心处的圆球和四个设置在正方体基材一侧平面圆角圆心处的金属棒;圆球为直径为2mm的碳钢钢球24,且圆球的一半嵌入在正方体基材一侧平面中心处孔槽内,另一半悬空,用于交叉线对中和零切片位置的评估;四个金属棒的直径相同,且长度不同,分别为底面积直径为3mm*8mm的黄铜棒14、底面积直径为3mm*12mm的黄铜棒17、底面积直径为3mm*16mm的黄铜棒21和底面积直径为3mm*20mm的的黄铜棒23,基准定位切片位置与深度,且用于检测CT的Z轴分辨率和3D重建的空间分辨率、并可以通过质心测算,计算图像的几何畸变和放大。As shown in Figure 3, the reference module includes a ball arranged at the center of the plane on one side of the cube substrate and four metal rods arranged at the center of the rounded corners on one side of the cube substrate; the ball is a carbon steel ball 24 with a diameter of 2 mm, and half of the ball is embedded in the hole at the center of the plane on one side of the cube substrate, and the other half is suspended in the air for the centering of crossing lines and the evaluation of the zero slice position; the diameters of the four metal rods are the same, and the lengths are different. A brass rod 17 with a diameter of 3mm*12mm, a brass rod 21 with a bottom area diameter of 3mm*16mm, and a brass rod 23 with a bottom area diameter of 3mm*20mm are used to locate the position and depth of the slice as a reference, and are used to detect the Z-axis resolution of CT and the spatial resolution of 3D reconstruction, and calculate the geometric distortion and magnification of the image through centroid calculation.

如图3、图5和图6所示,乳房X线摄影模块包括六个圆形阵列平均分布在正方体基材一侧平面内圈的正方体、七个线性分布在圆球左侧的金属球和八个线性分布在圆球右侧的线条;六个正方体的大小不同,且分别由尼龙材质制成,六个正方体分别为尺寸为2mm*2mm*2mm的尼龙正方体13、尺寸为3mm*3mm*3mm的尼龙正方体15、尺寸为4mm*4mm*4mm的尼龙正方体16、尺寸为6mm*6mm*6mm的尼龙正方体19、尺寸为8mm*8mm*8mm的尼龙正方体20和尺寸为10mm*10mm*10mm的尼龙正方体22,用于测试乳腺X线摄影设备对低对比度组织的成像质量;七个金属球的直径不同,七个金属球分别为直径为3mm的碳钢钢珠31、直径为2mm的碳钢钢珠32、直径为1.5mm的碳钢钢珠33、直径为1mm的碳钢钢珠34、直径为0.7mm的碳钢钢珠35、直径为0.5mm的碳钢钢珠36和直径为0.35mm的碳钢钢珠37,用于模拟乳腺摄影微钙化;八个线条分别为截面直径为3mm*20mm的橡胶线38、截面直径为2mm*20mm的橡胶线39、截面直径为1.5mm*20mm的橡胶线40、截面直径为1mm*20mm的橡胶线41、截面直径为0.8mm*20mm的橡胶线42、截面直径为0.6mm*20mm的橡胶线43、截面直径为0.5mm*20mm的橡胶线44和截面直径为0.4mm*20mm的橡胶线45,用于模拟乳腺腺体及组织结构,并可以通过钢球的密度投影,由配套计算机书案件自动计算成像系统的调制传递函数(MTF)。As shown in Fig. 3, Fig. 5 and Fig. 6, the mammography module includes six circular arrays of cubes evenly distributed on the inner plane of one side of the cube substrate, seven metal balls linearly distributed on the left side of the ball and eight lines linearly distributed on the right side of the ball; the six cubes have different sizes and are made of nylon material respectively. The six cubes are nylon cube 13 with a size of 2mm*2mm*2mm, nylon cube 15 with a size of 3mm*3mm*3mm, and a size of 4mm*4mm Nylon cube 16 with a size of 6mm*6mm*6mm, nylon cube 19 with a size of 6mm*6mm*6mm, nylon cube 20 with a size of 8mm*8mm*8mm, and nylon cube 22 with a size of 10mm*10mm*10mm are used to test the imaging quality of mammography equipment for low-contrast tissues; the diameters of the seven metal balls are different. Carbon steel ball 33 with a diameter of 1.5 mm, carbon steel ball 34 with a diameter of 1 mm, carbon steel ball 35 with a diameter of 0.7 mm, carbon steel ball 36 with a diameter of 0.5 mm, and carbon steel ball 37 with a diameter of 0.35 mm are used to simulate mammography microcalcification; the eight lines are respectively a rubber line 38 with a cross-sectional diameter of 3 mm*20 mm, a rubber wire 39 with a cross-sectional diameter of 2 mm*20 mm, and a cross-sectional diameter of 1.5 mm*20 mm rubber wire 40, rubber wire 41 with a cross-sectional diameter of 1mm*20mm, rubber wire 42 with a cross-sectional diameter of 0.8mm*20mm, rubber wire 43 with a cross-sectional diameter of 0.6mm*20mm, rubber wire 44 with a cross-sectional diameter of 0.5mm*20mm, and rubber wire 45 with a cross-sectional diameter of 0.4mm*20mm. MTF).

如图2和图4所示,普通X线摄影模块包括十二个圆形阵列平均分布在正方体基材一侧平面外围的圆柱体、六个线性分布在圆球上方的金属丝模块,每个金属丝模块的直径不同,金属丝模块由四根矩阵分布的直径相同的金属丝组成,四根金属丝之间的横纵间距与金属丝的直径相同,金属丝采用铜丝,用于检测成像的空间分辨率;十二个圆柱体的圆心连线是以圆球为圆心的圆环,可以用于配套计算机系统,基于圆心采集穿过12个圆柱的投影数值,根据数值可进行系统自动密度计算和对比,获得对比度数据;十二个圆柱体中六个直径不同的圆柱体是由环氧树脂制成,分别为底面积直径为2mm*2mm的环氧树脂圆柱体12、底面积直径为3mm*3mm的环氧树脂圆柱体1、底面积直径为4mm*4mm的环氧树脂圆柱体2、底面积直径为6mm*6mm的环氧树脂圆柱体3、底面积直径为8mm*8mm的环氧树脂圆柱体4和底面积直径为10mm*10mm的环氧树脂圆柱体5;六个金属丝模块分别为直径为0.1mm*1mm的铜丝模块25、直径0.2mm*2mm的铜丝模块26、直径为0.3mm*3mm的铜丝模块27、直径为0.4mm*4mm的铜丝模块28、直径为0.5mm*5mm的铜丝模块29、直径为0.6mm*6mm的铜丝模块30,用于检测成像的空间分辨率。As shown in Figures 2 and 4, the common X-ray photography module includes twelve circular arrays of cylinders evenly distributed on the periphery of one side of the cube substrate, and six wire modules linearly distributed above the sphere. The diameter of each wire module is different. The wire module is composed of four metal wires with the same diameter distributed in a matrix. The horizontal and vertical distances between the four wires are the same as the diameter of the wires. The center of the circle collects the projection values passing through 12 cylinders, and according to the values, the system can automatically calculate and compare the density to obtain contrast data; among the twelve cylinders, six cylinders with different diameters are made of epoxy resin, which are epoxy resin cylinders with a bottom area diameter of 2mm*2mm, epoxy resin cylinders with a bottom area diameter of 3mm*3mm, epoxy resin cylinders with a bottom area diameter of 4mm*4mm, epoxy resin cylinders with a bottom area diameter of 4mm*4mm, epoxy resin cylinders with a bottom area diameter of 6mm*6mm, epoxy resin cylinders with a bottom area diameter of 8mm*8mm The cylinder 4 and the epoxy resin cylinder 5 with a bottom area diameter of 10mm*10mm; the six wire modules are respectively a copper wire module 25 with a diameter of 0.1mm*1mm, a copper wire module 26 with a diameter of 0.2mm*2mm, a copper wire module 27 with a diameter of 0.3mm*3mm, a copper wire module 28 with a diameter of 0.4mm*4mm, a copper wire module 29 with a diameter of 0.5mm*5mm, and a copper wire module 30 with a diameter of 0.6mm*6mm. The spatial resolution used to detect imaging.

如图2和图3所示,计算机断层扫描模块包括十二个圆柱体中尺寸相同的六个圆柱体和以三十度角倾斜设置在正方体基材一侧平面上的圆柱;尺寸相同的六个圆柱体分别是由空气、泡桐、环氧树脂、尼龙以及ABS树脂制成,分别为底面积直径为20mm*20mm的环氧树脂圆柱体6、底面积直径为20mm*20mm的电木圆柱体7、底面积直径为20mm*20mm的尼龙圆柱体8、底面积直径为20mm*20mm的ABS树脂圆柱体9、底面积直径为20mm*20mm泡桐圆柱体10和底面积直径为20mm*20mm的空气圆柱体11,用于计算机断层扫描设备的HU线性和感光测定;所述圆柱是由电木制成,为底面积直径为2mm*20mm的倾斜电木圆柱体18,用于利用三角函数法检测CT扫描断面切片的厚度,即层厚。As shown in Figure 2 and Figure 3, the computed tomography module includes six cylinders of the same size among the twelve cylinders and a cylinder that is inclined at an angle of 30 degrees and is arranged on the plane of one side of the cube substrate; the six cylinders of the same size are respectively made of air, Paulownia, epoxy resin, nylon and ABS resin, and are respectively an epoxy resin cylinder 6 with a bottom area diameter of 20mm*20mm, a bakelite cylinder 7 with a bottom area diameter of 20mm*20mm, and a nylon cylinder 8 with a bottom area diameter of 20mm*20mm. An ABS resin cylinder 9 with a diameter of 20mm*20mm, a Paulownia cylinder 10 with a bottom area diameter of 20mm*20mm, and an air cylinder 11 with a bottom area diameter of 20mm*20mm are used for HU linearity and photosensitive measurement of computer tomography equipment; the cylinder is made of bakelite, which is an inclined bakelite cylinder 18 with a bottom area diameter of 2mm*20mm, which is used to detect the thickness of CT scanning section slices, that is, the layer thickness, using trigonometric functions.

为了减少或降低由于检测人员培训程度不同或主观判断产生检测误差的问题,本申请的另一种典型的实施方式中,提供了一种基于测试医学X线成像设备的体模的图像质量分析系统,包括灰度分析模块、空间分辨率分析模块、定位与变形分析模块、对比度分析模块、宽容度分析模块、几何畸变分析模块和主动选取ROI分析模块。In order to reduce or reduce the problem of detection errors due to different training levels of detection personnel or subjective judgments, another typical implementation of the present application provides an image quality analysis system based on a phantom for testing medical X-ray imaging equipment, including a gray scale analysis module, a spatial resolution analysis module, a positioning and deformation analysis module, a contrast analysis module, a tolerance analysis module, a geometric distortion analysis module, and an active ROI selection analysis module.

灰度分析模块,用于分析基准模块中十二个圆柱体、乳房X射线模块中六个正方体和八个线条的图像灰度,计算基准模块和乳房X射线模块灰度。The grayscale analysis module is used to analyze the image grayscales of the twelve cylinders in the reference module, six cubes and eight lines in the mammogram module, and calculate the grayscale of the reference module and the mammogram module.

空间分辨率分析模块,用于分析普通X线摄影模块中八个金属丝模块,通过每个金属丝模块中金属丝横纵间距计算分辨率。The spatial resolution analysis module is used to analyze the eight wire modules in the common X-ray photography module, and the resolution is calculated through the horizontal and vertical spacing of the wires in each wire module.

定位与变形分析模块,用于分析普通X线摄影模块中八个金属丝模块和四个金属棒,通过金属丝横纵间距差异计算空间位置和变形。The positioning and deformation analysis module is used to analyze the eight wire modules and four metal rods in the ordinary X-ray photography module, and calculate the spatial position and deformation through the difference in the horizontal and vertical spacing of the metal wires.

对比度分析模块,用于计算普通X线摄影模块中十二个圆柱体的高低对比度材质的成像效果。The contrast analysis module is used to calculate the imaging effects of the high and low contrast materials of the twelve cylinders in the general X-ray photography module.

宽容度分析模块,用于分析乳房X射线模块中七个金属球和八个线条,确定设备图像的显示宽容度。The tolerance analysis module is used to analyze the seven metal balls and eight lines in the mammography module to determine the display tolerance of the device image.

几何畸变分析模块,用于分析计算机断层扫描模块中圆柱,测试图像的几何畸变。The geometric distortion analysis module is used to analyze the cylinder in the computed tomography module and test the geometric distortion of the image.

主动选取ROI分析模块,用于自助选取ROI进行分辨率、线性度、对比度、几何畸变、空间分辨率、定位的图像测试。Actively select the ROI analysis module, which is used to self-select ROI for image testing of resolution, linearity, contrast, geometric distortion, spatial resolution, and positioning.

该图像质量分析系统是基于Matlab算法层面的封装系统,该图像质量分析系统可以在X线设备连接的工作站上运行,同样也可以在普通计算机上运行,该图像质量分析系统的可分析内容为分析模拟X线成像、数字X线成像、乳腺X线成像、CR、DR、透视等平面X线设备图像的灰度、分辨率,以及CT成像的空间分辨率、对比度、线性度、几何畸变、放大率、调制传递函数和Z轴空间分辨率。其具体工作过程为:图像质量分析系统可根据灰度,测试图像中基材与各模块组件的密度差异、对比度;可根据分辨率体素,测试图像中模块的间隔与形状,以及线性度;图像质量分析系统根据计算机断层扫描设备扫描所得DICOM图像重建的3D模型,DICOM图像的灰度,以及DICOM图像的分辨率分析扫描设备成像图像质量的空间分辨率、对比度、线性度、几何畸变、放大率、调制传递函数和Z轴空间分辨率,图像质量分析系统还可以自主选取感兴趣区域(ROI),并对选取的ROI进行分析,测试得出密度、对比度、分辨率等数据信息;从而准确得测试结果,排除测试过程中,测试人员主观判断的失误,并缩短测试时间。The image quality analysis system is a packaging system based on the Matlab algorithm level. The image quality analysis system can run on workstations connected to X-ray equipment, and can also run on ordinary computers. The analyzable content of the image quality analysis system is to analyze the gray scale and resolution of plane X-ray equipment images such as analog X-ray imaging, digital X-ray imaging, mammography, CR, DR, and perspective, as well as the spatial resolution, contrast, linearity, geometric distortion, magnification, modulation transfer function, and Z-axis spatial resolution of CT imaging. The specific working process is as follows: the image quality analysis system can test the density difference and contrast between the base material and each module component in the image according to the grayscale; it can test the interval, shape and linearity of the modules in the image according to the resolution voxel; the image quality analysis system can analyze the spatial resolution, contrast, linearity, geometric distortion, magnification, modulation transfer function and Z-axis spatial resolution of the image quality of the scanning device based on the 3D model reconstructed from the DICOM image scanned by the computer tomography equipment, the gray level of the DICOM image, and the resolution of the DICOM image. Independently select a region of interest (ROI), analyze the selected ROI, and test to obtain data information such as density, contrast, and resolution; thereby accurately obtain test results, eliminate subjective judgment errors by testers during the test process, and shorten test time.

本申请的另一种典型的实施方式中,提供了一种测试医学X线成像设备的体模的工作方法,其特征是,包括以下步骤:In another typical implementation of the present application, a working method for testing a phantom of medical X-ray imaging equipment is provided, which is characterized in that it includes the following steps:

(1)准备工作:将体模放置在乳腺X线摄影、普通X线摄影或计算机断层扫描设备的检查床上,摆正体位,准备扫描;(1) Preparation: Place the phantom on the examination bed of mammography, general X-ray photography or computed tomography equipment, adjust the body position, and prepare for scanning;

(2)扫描工作:调整乳腺X线摄影、普通X线摄影或计算机断层扫描设备的扫描视野,使扫描视野将体模完全覆盖,继续对体模进行扫描,得到相应的检查图像;(2) Scanning work: adjust the scanning field of view of mammography, general X-ray photography or computed tomography equipment so that the scanning field of view completely covers the phantom, and continue to scan the phantom to obtain corresponding inspection images;

(3)将步骤(2)中得到的检查图像导入到图像质量分析系统中,在菜单中选择图像来源设备,选择需要检测的参数信息,点选进行分析;(3) Import the inspection image obtained in step (2) into the image quality analysis system, select the image source device in the menu, select the parameter information to be detected, and click to analyze;

(4)图像质量分析系统将自动分析图像数据结果,并与参数正常、成像标准的设备的图像数据进行对比,若参数浮动在一定范围内,则成像质量正常,否则,需要对设备进行调试。(4) The image quality analysis system will automatically analyze the image data results and compare them with the image data of equipment with normal parameters and imaging standards. If the parameters fluctuate within a certain range, the imaging quality is normal. Otherwise, the equipment needs to be debugged.

上述虽然结合附图对本发明的具体实施方式进行了描述,但并非对本发明保护范围的限制,所属领域技术人员应该明白,在本发明的技术方案的基础上,本领域技术人员不需要付出创造性劳动即可做出的各种修改或变形仍在本发明的保护范围以内。Although the specific implementation of the present invention has been described above in conjunction with the accompanying drawings, it does not limit the protection scope of the present invention. Those skilled in the art should understand that on the basis of the technical solution of the present invention, various modifications or deformations that those skilled in the art can make without creative labor are still within the protection scope of the present invention.

Claims (8)

1. A phantom for testing imaging quality of various medical X-ray equipment is characterized by comprising two cube base materials, wherein four corners of each cube base material are respectively provided with a fillet; the two square base materials are closely attached together through the insertion of the modules arranged in the mirror image distribution hole grooves; the X-ray imaging device comprises a square base material and is characterized in that a reference module, a mammography module, a common X-ray radiography module and a computer tomography module are arranged on one side plane of the square base material, and the reference module comprises a sphere arranged at the center of one side plane of the square base material and four metal rods arranged at the circle centers of round corners of one side plane of the square base material; the mammography module comprises six cubes which are evenly distributed on the plane inner ring at one side of the cube base material in a circular array mode, seven metal balls which are linearly distributed on the left side of the round ball, and eight lines which are linearly distributed on the right side of the round ball; the common X-ray photography module comprises twelve circular arrays evenly distributed on the periphery of one side plane of the square base material and six metal wire modules linearly distributed above the sphere, wherein the diameters of the metal wire modules are different, and the metal wire modules consist of four metal wires with the same diameters distributed in a matrix; the computer tomography module comprises six cylinders with the same size in twelve cylinders and a cylinder obliquely arranged on one side plane of the cube base material at an angle of thirty degrees; the reference module, the mammography module, the common radiography module and the computer tomography module are respectively placed in corresponding holes and grooves on one side plane of the cube base material;
the cube base material is prepared by two polyethylene cubes;
the round ball is a carbon steel ball, one half of the round ball is embedded in a hole groove at the center of one side plane of the square base material, and the other half of the round ball is suspended; the four metal bars are brass bars respectively; the four metal bars have the same diameter and different lengths.
2. The phantom for testing imaging quality of various medical X-ray apparatuses according to claim 1, wherein the six cubes are different in size and made of nylon materials, respectively; the diameters of the seven metal balls are different, and the seven metal balls are carbon steel balls; the diameters of the eight lines are different, and rubber lines are adopted respectively.
3. The phantom for testing imaging quality of various medical X-ray devices according to claim 1, wherein the connecting line of the circle centers of the twelve cylinders is a circular ring with a sphere as the circle center; six cylinders with different diameters in the twelve cylinders are made of epoxy resin; the transverse and longitudinal distances among the four metal wires are the same as the diameters of the metal wires, and the metal wires are copper wires.
4. The phantom for testing the imaging quality of a plurality of medical X-ray apparatuses according to claim 1, wherein the six cylinders of the same size are made of air, paulownia, epoxy, nylon and ABS resin, respectively; the cylinder is made of bakelite.
5. An image quality analysis system based on the body model for testing imaging quality of various medical X-ray devices according to claim 1, which is characterized by comprising a gray level analysis module, a spatial resolution analysis module, a positioning and deformation analysis module, a contrast analysis module, a latitude analysis module, a geometric distortion analysis module and an active selection ROI analysis module;
the gray level analysis module is used for analyzing the image gray levels of twelve cylinders in the reference module, six cubes and eight lines in the X-ray breast module and calculating the gray levels of the reference module and the X-ray breast module;
the spatial resolution analysis module is used for analyzing eight metal wire modules in the common X-ray photography module and calculating resolution through the transverse and longitudinal spacing of the metal wires in each metal wire module;
the positioning and deformation analysis module is used for analyzing eight metal wire modules and four metal rods in the common X-ray photography module and calculating the space position and deformation through the difference of the transverse and longitudinal spacing of the metal wires;
the contrast analysis module is used for calculating the imaging effect of high-low contrast materials of twelve cylinders in the common X-ray photography module;
the latitude analysis module is used for analyzing seven metal balls and eight lines in the breast X-ray module and determining the display latitude of the equipment image;
the geometric distortion analysis module is used for analyzing the geometric distortion of the cylinder and the test image in the computed tomography module;
the active ROI selection analysis module is used for self-help ROI selection for image testing of resolution, linearity, contrast, geometric distortion, spatial resolution and positioning.
6. A method of operating a phantom for testing imaging quality of a plurality of medical X-ray devices based on claim 1, comprising the steps of:
(1) Placing a phantom on an inspection bed of the equipment, setting the body position, and preparing for scanning;
(2) Adjusting the scanning visual field of the equipment to enable the scanning visual field to cover the body model completely, and continuing to scan the body model to obtain a corresponding checking image;
(3) Importing the inspection image obtained in the step (2) into an image quality analysis system, selecting image source equipment from a menu, selecting parameter information to be detected, and clicking for analysis;
(4) The image quality analysis system automatically analyzes the image data result and compares the image data result with the image data of equipment with normal parameters and imaging standards, if the parameters float in a certain range, the imaging quality is normal, otherwise, the equipment needs to be debugged.
7. The method of claim 6, wherein in step (1), the apparatus is a mammography, a plain radiography, or a computed tomography apparatus.
8. The method according to claim 6, wherein in the step (4), the image quality analysis system analyzes the gray scale and resolution of the image of the planar X-ray device such as analog X-ray imaging, digital X-ray imaging, breast X-ray imaging, CR, DR, perspective, etc. according to the gray scale and resolution of the image obtained by mammography and plain X-ray scanning; the image quality analysis system analyzes the spatial resolution, contrast, linearity, geometric distortion, magnification, modulation transfer function and Z-axis spatial resolution of CT imaging image quality according to a 3D model reconstructed by the DICOM image obtained by scanning the computer tomography device, the gray level of the DICOM image and the resolution of the DICOM image.
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