CN106901765A - A kind of PET/MR image quality detection body mould of apery head and preparation method thereof - Google Patents
A kind of PET/MR image quality detection body mould of apery head and preparation method thereof Download PDFInfo
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- CN106901765A CN106901765A CN201710169602.3A CN201710169602A CN106901765A CN 106901765 A CN106901765 A CN 106901765A CN 201710169602 A CN201710169602 A CN 201710169602A CN 106901765 A CN106901765 A CN 106901765A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/58—Testing, adjusting or calibrating apparatus or devices for radiation diagnosis
- A61B6/582—Calibration
- A61B6/583—Calibration using calibration phantoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/58—Calibration of imaging systems, e.g. using test probes, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material
Abstract
A kind of PET/MR image quality the invention discloses apery head detects body mould and preparation method thereof, including：The PET/MR image quality detection mould of the apery head has the body mould body of human body head configuration, and the body mould body is internally provided with least one dismountable replacement module；Dismountable replacement module is selected from one or more in brain tumor analog module, the image co-registration degree test module of PET/MR, the correction for attenuation test module of PET/MR, PET performance parameter tests module or MRI performance parameter test modules.Body mould of the invention is the quality testing body mould with morphological feature, it is capable of human body head profile, structure and the focus of simulating realistic, can be used for carrying out quality control to human body head PET/MR imagers, can be also used for find PET/MR imagers optimal sweep parameter, for demonstration lesson, for tracer screening etc. aspect, be with a wide range of applications.
Description
Technical field
The present invention relates to PET/MR quality assurances and field of quality control, more particularly to a kind of PET/MR of apery head
Image quality detection body mould and preparation method thereof.
Background technology
In recent years, with the fast development of medical imaging technology, multi-modal joint imaging technology has obtained extensive concern,
Such as PET/MR, (Positron Emission Tomography/Magnetic Resonance Imaging, positron emission is broken
Layer imaging/magnetic resonance imaging) technology, wherein, PET can well obtain function and metabolic information, belong to functional imaging, right
There is sensitivity higher in pathological tissues, but its spatial resolution is relatively low, it is impossible to PET information is accurately positioned；And
MRI image has splendid soft tissue contrast and high spatial resolution.(PET/MR is multi-modal two-in-one for the joint of PET and MRI
Imaging system) deficiency that independent PET imagings and independent MRI are imaged can be made up, body can be simultaneously obtained in once checking
Dissection, function and biochemical multiple information.
Be presently used for PET/MR imager quality controls body mould there are problems that species it is single, for example,
Existing PET/MR imaging bodies mould is only some simple geometric shapes, and be only capable of testing independent PET parts performance parameter or
The performance parameter of independent MRI parts, it is impossible to which the image quality being used in combination to PET/MR carries out Quality Control.Therefore, need badly a kind of suitable
For PET/MR imagers with body mould.
The content of the invention
For above-mentioned the deficiencies in the prior art, the PET/MR it is an object of the invention to provide a kind of apery head is imaged matter
Amount detection body mould.Body mould of the invention is the 3-D solid structure quality testing body mould with morphological feature, can be emulated true
Real people's cranium brain profile, structure and focus, can be used for carrying out quality control to the PET/MR imagers of human body head, may be used also
For finding the optimal sweep parameter of PET/MR imagers, for demonstration lesson, for aspects such as tracer screenings, with wide
General range of application.
To achieve the above object, the present invention is adopted the following technical scheme that：
A kind of the first aspect of the present invention, there is provided the PET/MR image quality detection body mould of apery head, including：With people
The body mould body of body head configuration, the body mould body is internally provided with least one dismountable replacement module；
Dismountable replacement module be selected from brain tumor analog module, the image co-registration degree test module of PET/MR,
One kind or many in the correction for attenuation test module of PET/MR, PET performance parameter tests module or MRI performance parameter test modules
Kind.
Preferably, dismountable replacement module is located at the brain localization of the top inside body mould body.
Preferably, the brain tumor analog module is hollow ball structure；It is perfused with the hollow ball structure and is shown
Track agent.
It is more highly preferred to, the tracer is that 18F-FDG (fluorodeoxyglucose, fluorodeoxyglucose) is molten
Liquid.
Preferably, the image co-registration degree test module of the PET/MR includes：In hollow cylinder, hollow ball or square
At least one；Hollow cylinder, hollow ball or square can individually carry out image co-registration degree test.
Tracer, such as FDG solution are filled with the hollow ball or square.
Various sizes of solid source, such as Na sources are accommodated in the hollow cylinder.
It is more highly preferred to, the hollow ball composition circumference of multiple different-diameter sizes, the centre of sphere of the hollow ball is same
On one circumferential layer；Or the hollow ball is in line by diameter.
During test, FGD solution is injected in hollow ball or square, PET/MR scannings are carried out, according to the scanning for obtaining
Image obtains image co-registration accuracy.
It is more highly preferred to, the hollow cylinder composition circumference of multiple different-diameter sizes, the center of circle in the hollow cylinder section
On same circumferential layer；Or the hollow cylinder is in line by diameter.
During test, Na sources are injected in hollow cylinder, carry out PET/MR scannings, image is obtained according to the scan image for obtaining
Fusion accuracy.
Preferably, the image co-registration degree test module of the PET/MR of hollow ball or square composition can be also used for
Test the low contrast resolution of PET.
The method of testing of the low contrast resolution of PET is：Hollow ball or square body examination using multiple different-diameters
The low contrast resolution of PET is tried, during test, tracer is injected in multiple hollow balls or square, carry out PET scan,
Scan image according to obtaining determines low contrast resolution.
Preferably, the correction for attenuation test module of the PET/MR, including：At least one hollow cylinder plug-in unit, the sky
Heart cylinder plug is divided into two parts, and a part is located in the body mould body, and it is external that another part is located at the body calligraphy or painting model.
The hollow cylinder plug-in unit is located at the part and equal positioned at the external part of the body calligraphy or painting model in the body mould body
Filled with tracer, such as FDG solution.
Part and connected using screw thread positioned at the external part of body calligraphy or painting model that the hollow cylinder plug-in unit is located in body mould body
Connect.
During test, the part that is located in body mould body in hollow cylinder plug-in unit and inject positioned at the external part of body calligraphy or painting model
Tracer, carries out PET/MR scannings, the image of the part being located at according to the hollow cylinder plug-in unit that obtains of scanning in body mould body and
The counting of the image of the part that hollow cylinder plug-in unit is located in body mould body determines the accuracy of correction for attenuation.
Preferably, the PET performance parameter tests module, is made up of the cylinder of some groups of different-diameters.
The cylinder is hollow or solid construction.
When cylinder is hollow-core construction, for testing the systemic resolution under comparison structure high, during test in cylinder
Filling tracer (such as FGD solution).
When cylinder be solid construction when, for testing the systemic resolution under low comparison structure, during test cylinder it
The filling tracer in outer region.
During test, PET scan is carried out after filling tracer, according to the minimum dimension that scanning obtains to be differentiated in image
(diameter) determines resolution ratio.
Preferably, the MRI performance parameter tests module, including：MRI high-contrasts module resolution and the low contrasts of MRI
Degree module resolution；
The MRI high-contrasts module resolution is made up of the circular hole of some groups of different-diameters, for testing measurement imaging
System is when without critical noisy to the resolution capability of object minimum details.Test object is observed using ocular estimate.
The MRI low contrast resolutions module is made up of the circular hole of some groups of different-diameters for radially distributing；Often
The diameter of one group of circular hole is identical, and the depth of each group of circular hole is different.
For above-mentioned the deficiencies in the prior art, the PET/MR it is an object of the invention to provide a kind of apery head is imaged matter
The preparation method of amount detection body mould.Body mould of the invention is the 3-D solid structure quality testing body mould with morphological feature,
It is capable of people's cranium brain profile, structure and the focus of simulating realistic, can be used for carrying out matter to the PET/MR imagers of human body head
Amount control, can be also used for find PET/MR imagers optimal sweep parameter, for demonstration lesson, for tracer screening etc.
Aspect, is with a wide range of applications.
To achieve the above object, the present invention is adopted the following technical scheme that：
The second aspect of the present invention, there is provided above-mentioned apery head PET/MR image quality detects the preparation method of body mould, step
It is rapid as follows：
(1) CT scan data according to human body head builds the body mould body with human body head profile；
(2) at least one dismountable replacement module is set in the inside of the body mould body for building.
In step (1), the skeletal structure of the body mould body carries out 3 D-printing, body using the tissueequivalentmaterial of bone
The skin of mould body and other interior tissues carry out 3 D-printing using soft tissue equivalent material.
Or, the skeletal structure of the body mould body carries out 3 D-printing, body mould body using skeletal tissue's equivalent material
Skin be that scalp portions carry out 3 D-printing using common material, its hetero-organization inside body mould body is soft using what is prepared
Tissueequivalentmaterial is irrigated.
Skeletal tissue's equivalent material, the soft tissue equivalent material, the common material are existing material, institute
It is Ago-Gel that is existing or preparing to state the soft tissue equivalent material for preparing：
For example, skeletal tissue's equivalent material is high density tree of the shore hardness more than 90 in existing 3D printing material
Fat.
The soft tissue equivalent material is the relatively low EVA resin of existing 3D printing material Midst density.
The common material is common plastic material in existing 3D printing material.
The soft tissue equivalent material for preparing is the Ago-Gel prepared.
For above-mentioned the deficiencies in the prior art, the PET/MR it is an object of the invention to provide above-mentioned apery head is imaged matter
Amount detection body mould PET/MR imagers quality control, find the optimal sweep parameter of PET/MR imagers, demonstration lesson and/
Or the purposes in the screening of tracer.Body mould of the invention is the 3-D solid structure quality testing body with morphological feature
Mould, is capable of people's cranium brain profile, structure and the focus of simulating realistic, can be used for carrying out the PET/MR imagers of human body head
Quality control, can be also used for finding the optimal sweep parameter of PET/MR imagers, is screened for demonstration lesson, for tracer
Etc. aspect, be with a wide range of applications.
To achieve the above object, the present invention is adopted the following technical scheme that：
The third aspect of the present invention, there is provided the PET/MR image quality detection body mould of above-mentioned apery head is imaged in PET/MR
Use in the quality control of instrument, the optimal sweep parameter for finding PET/MR imagers, demonstration lesson and/or the screening of tracer
On the way.
Beneficial effects of the present invention：
(1) the PET/MR image quality detection mould of apery head of the invention has 3-D solid structure, can be outside
The form and construction of human body head are simulated in form and internal structure.In addition, the PET/MR imagings of apery head of the invention
Quality testing mould has one or more dismountable replacement modules, wherein, a replacement module is default lesion structure, is used
To simulate the tumour in human body head；Other replacement modules can be used for testing the parameter of PET/MR instrument, so that according to measuring
Parameter evaluate the quality of PET/MR instrument performances.
(2) the PET/MR image quality detection body mould of apery head of the invention can be outside simulating realistic human body head cranium brain
Shape, structure and focus, can be used for carrying out quality control to human body head PET/MR imagers, can be also used for finding PET/
The optimal sweep parameter of MR imagers, for demonstration lesson, for tracer screening etc. aspect, with wider range of application.
Brief description of the drawings
The Figure of description for constituting the part of the application is used for providing further understanding of the present application, and the application's shows
Meaning property embodiment and its illustrated for explaining the application, does not constitute the improper restriction to the application.
Fig. 1 is the structural representation of body mould body of the invention；
Fig. 2 is that the PET/MR image quality of apery head of the present invention detects tumour analog module structural representation in body mould
(side cutaway view)；
Fig. 3 A be apery head of the present invention PET/MR image quality detection body mould in image co-registration degree test module sky
The top view of bulbus cordis body；
Fig. 3 B be apery head of the present invention PET/MR image quality detection body mould in image co-registration degree test module sky
The front view of bulbus cordis body；
Fig. 4 A be apery head of the present invention PET/MR image quality detection body mould in image co-registration degree test module sky
The top view of heart cylinder；
Fig. 4 B be apery head of the present invention PET/MR image quality detection body mould in image co-registration degree test module sky
The front view of heart cylinder；
Fig. 5 be apery head of the present invention PET/MR image quality detection body mould in PET/MR correction for attenuation test module
Structural representation；
Fig. 6 A are the sectional view of PET high-contrast module resolutions；
Fig. 6 B are the sectional view of PET low contrast resolution modules；
Fig. 7 A：The structural representation of MRI high-contrast module resolutions；
Fig. 7 B：The structural representation of MRI low contrast resolution modules；
Wherein, 1- skins, 2- bones, the dismountable replacement modules of 3-, 4- brain tissues, 5- hollow balls, 6- hollow cylinders
Plug-in unit, 7- hollow cylinders plug-in unit is located at the part in body mould body, and 8- hollow cylinders plug-in unit is located at the external part of body calligraphy or painting model.
Specific embodiment
It is noted that described further below is all exemplary, it is intended to provide further instruction to the application.Unless another
Indicate, all technologies used herein and scientific terminology are with usual with the application person of an ordinary skill in the technical field
The identical meanings of understanding.
It should be noted that term used herein above is merely to describe specific embodiment, and be not intended to restricted root
According to the illustrative embodiments of the application.As used herein, unless the context clearly indicates otherwise, otherwise singulative
Be also intended to include plural form, additionally, it should be understood that, when in this manual use term "comprising" and/or " bag
Include " when, it indicates existing characteristics, step, operation, device, component and/or combinations thereof.
As background technology is introduced, in the prior art there is species in the body mould for PET/MR imager quality controls
The problems such as single, simple structure, it is impossible to which the image quality being used in combination to PET/MR carries out Quality Control.Based on this, the present invention is proposed
A kind of PET/MR image quality detection body mould of apery head and preparation method thereof.
In a kind of embodiment of the application, there is provided a kind of PET/MR image quality detection body mould of apery head,
As shown in figure 1, the form of the profile simulation real human body head cranium brain of the body mould body, the top brain inside body mould body
Position installs and is equipped with least one dismountable replacement module 3；Dismountable replacement module 3 can be cuboid, also may be used
To be cylinder, its shape is not limited herein.The body mould body includes skin 1, bone 2, removably replaces mould
Block 3 and brain tissue 4.
For example, after the overall making of perfect aspect mould body, brain localization takes a cuboid above body mould body
A, after cuboid A is removed, can select corresponding dismountable replacement module 3 and be arranged on body mould according to test needs.When not
When needing to install replacement module, cuboid A can be reinstalled on body mould body, now, body mould is complete human body's head cranium brain
Form.
Dismountable replacement module 3 be selected from brain tumor analog module, the image co-registration degree test module of PET/MR,
One kind or many in the correction for attenuation test module of PET/MR, PET performance parameter tests module or MR performance parameter test modules
Kind.
For example, replacement module B1 is used to simulate brain tumor analog module；
Replacement module C1 is the image co-registration degree test module of PET/MR, and replacement module C2 is surveyed for the correction for attenuation of PET/MR
Die trial block；
Replacement module D1 is a kind of PET performance parameter tests module, and replacement module D2 is another kind PET performance parameter tests
Module etc.；
Replacement module E1 is a kind of MRI performance parameter tests module, and replacement module E2 is another kind MRI performance parameter tests
Module.
As preferred scheme, the shape of tumor in human body head is simulated with sphere structure, as shown in Fig. 2 sphere structure
Interior perfusion tracer, such as can enter after 18F-FDG (fluorodeoxyglucose, fluorodeoxyglucose) solution under PET
Row imaging.
Used as preferred scheme, the image co-registration degree test module of the PET/MR includes：Hollow cylinder, spheroid 5 or just
At least one in cube；Hollow cylinder, hollow ball 5 or square can individually carry out image co-registration degree test.
Tracer, such as FDG solution are filled with the hollow ball 5 or square.
Preferably, the hollow ball composition circumference of multiple different-diameter sizes, the centre of sphere of the hollow ball 5 is in same circle
On perisphere, as shown in Figure 3A；Or the hollow ball 5 is in line by diameter, as shown in Figure 3 B.
The image co-registration degree test module of above-mentioned PET/MR can be also used for testing the low contrast resolution of PET.
Method of testing is：The low contrast resolution of PET is tested using the hollow ball 5 of multiple different-diameters, during test,
FDG solution is injected in multiple hollow balls 5, PET scan is carried out, determines that low contrast is differentiated according to the scan image for obtaining
Rate.
Preferably, the hollow cylinder composition circumference of multiple different-diameter sizes, the center of circle in the hollow cylinder section is same
On one circumferential layer, as shown in Figure 4 A；Or the hollow cylinder is in line by diameter, as shown in Figure 4 B.
During test, Na sources are injected in hollow cylinder, carry out PET/MR scannings, image is obtained according to the scan image for obtaining
Fusion accuracy.
As preferred scheme, the correction for attenuation test module of the PET/MR, including：At least one hollow cylinder plug-in unit
6,6 points of the hollow cylinder plug-in unit is two parts, and a part is located in the body mould body, and another part is located at the body calligraphy or painting model
In vitro, as shown in Figure 5.
The part 7 and hollow cylinder plug-in unit that the hollow cylinder plug-in unit is located in body mould body are located at the external portion of body calligraphy or painting model
8 are divided to be filled with tracer, such as FDG solution.
Due to needing to hold FDG solution in hollow cylinder plug-in unit, therefore the requirement of its material does not react i.e. with FDG solution
Can.
Preferably, the part 7 and hollow cylinder plug-in unit that the hollow cylinder plug-in unit is located in body mould body are located at body calligraphy or painting model
External part 8 is using threaded connection.
During test, the part 7 and hollow cylinder plug-in unit being located in body mould body in hollow cylinder plug-in unit are located at body mould body
FDG solution is injected in outer part 8, carries out PET/MR scannings, and body mould body is located at according to the hollow cylinder plug-in unit that scanning is obtained
The interior image of part 7 and hollow cylinder plug-in unit determine the essence of correction for attenuation positioned at the counting of the external image of part 8 of body calligraphy or painting model
Exactness.
Used as preferred scheme, the PET performance parameter tests module includes：PET high-contrasts resolution module and PET are low
Contrast resolution module；
Wherein, PET high-contrasts resolution module is used for the systemic resolution tested under comparison structure high, specifically, in circle
There are 6 circular holes in region, the diameter of the circular hole in different zones in the lucite of plate-like.The sectional view of borehole structure is such as
Shown in Fig. 6 A.
During test, the filling tracer in circular hole.
PET low contrast resolutions module is used for the systemic resolution tested under low comparison structure, and specifically, module is by 6
The solid cylinder composition of group different-diameter, sectional view is as shown in Figure 6B.
During test, the filling tracer in region outside cylinder.
Used as preferred scheme, the MRI performance parameter tests module includes：MRI high-contrasts module resolution and MRI
Low contrast resolution module.
Wherein, the high-contrast resolution ratio of MRI is to measure imaging system in no critical noisy to object minimum details
Resolution capability, conventional method is that test object is observed using ocular estimate.
In one embodiment of the invention, high-contrast resolution ratio is tested with the cavernous structure of different-diameter, specifically
Ground, is made up of in discoid lucite the solid cylinder of 6 groups of different-diameters, and the diameter of the circular hole in different zones is not
Deng as shown in 7A.
MRI contrast resolutions refer to when having low contrast between details and background, details to be identified from background
The ability come.The size of low contrast resolution reflects the ability of the close object of MRI machine resoluting signal size, that is,
The sensitivity level of MRI machine.When low contrast resolution is tested, for same material, when the timing of the condition of scanning one, its letter
The factors such as number intensity and the area and depth of target substance are relevant.For example, for the circular hole of same diameter, circular hole is deeper,
Its signal intensity is bigger.
Specifically, the module is made up of the circular hole of ten groups of different-diameters, and radially distributes, as shown in Figure 7 B, every group
In three Circularhole diameters it is identical, the depth of three circular holes in every group is different.For example, three depth of circular hole in same group
Increase successively from inside to outside.
It should be noted that in Fig. 6 A, Fig. 6 B, structure shown in Fig. 7 A and Fig. 7 B, the number of circular hole/cylindrical region and
The quantity of circular hole/cylinder is used merely as illustrating, illustrates in each region that figure below is drawn, rather than limitation of the present invention.
Specific number can be increased and decreased according to actual needs.
I can clearly understand the technical scheme of the application in order that obtaining those skilled in the art, below with reference to
Specific embodiment describes the technical scheme of the application in detail.
Test material used is the conventional test material in this area in the embodiment of the present invention, can be by commercial channel
It is commercially available.
Embodiment 1：
1. the structure and material of body mould body：
Body mould monnolithic case is the form of simulated humanbody head.Specifically, the MR scan datas according to real human body head
Simulated humanbody head model is built, and simulated humanbody head model is made by 3D printing technique according to constructed model.
(1) selection of cast material：
The structure of all bones 2 of human body head carries out 3 D-printing using skeletal tissue's equivalent material；The skin of human body head
Other interior tissues (brain tissue 4) of skin 1 and human body head carry out 3 D-printing using soft tissue equivalent material.
Wherein, skeletal tissue's equivalent material is high-density resin of the shore hardness more than 90 in existing 3D printing material.
Soft tissue equivalent material is the relatively low EVA resin of existing 3D printing material Midst density.
(2) structure of body mould：
Body mould includes：One individual mould body, has a dismountable replacement module 3 (for example, such as Fig. 1 institutes on body mould body
Show, positioned at the top brain localization of human head model).When dismountable replacement module 3 is installed on body mould body,
Model is a form for complete human body's head.Wherein, dismountable replacement module 3 can be cuboid, or cylinder
Body, does not limit its shape herein.
After detachable replacement module is pulled down, other replacement modules can be arranged on body mould body, with logical
Cross the corresponding parameter of module testing replaced.
Other replacement modules can be：Brain tumor analog module, the image co-registration degree test module of PET/MR, PET/
The correction for attenuation test module of MR, PET performance parameter tests module, MR performance parameter test modules.
Embodiment 2：
1. the structure and material of body mould body：
Body mould monnolithic case is the form of human body head.Specifically, the MR scan datas according to real human body head build
Human head model, and human head model is made by 3D printing technique according to constructed model.
(1) selection of cast material：
The structure of all bones 2 of human body head is printed using bone equivalent material, and the skin 1 of human body head is using general
Logical material is made, and other tissues (brain tissue 4) inside human body head are entered using the soft tissue equivalent material for preparing
Row form.
Bone equivalent material is high-density resin of the shore hardness more than 90 in existing 3D printing material.
Common material is common plastic material in existing 3D printing material.
The soft tissue equivalent material for preparing is the Ago-Gel prepared.
(2) structure of body mould：
Body mould includes：One individual mould body, has two dismountable replacement modules 3 (for example, such as Fig. 1 institutes in body mould body
Show, positioned at the top brain localization of human head model), wherein, a replacement module is brain tumor analog module, presets disease
Stove structure, is used to simulate the tumour in human body head；The image co-registration degree that other replacement modules can be selected from PET/MR is tested
Module, the correction for attenuation test module of PET/MR, PET performance parameter tests module or MR performance parameter test modules, for surveying
The parameter of PET/MR imagers is tried, so as to evaluate the quality of PET/MR imager performances according to the parameter for measuring.
The preferred embodiment of the application is the foregoing is only, the application is not limited to, for the skill of this area
For art personnel, the application can have various modifications and variations.It is all within spirit herein and principle, made any repair
Change, equivalent, improvement etc., should be included within the protection domain of the application.
Claims (10)
1. a kind of PET/MR image quality of apery head detects body mould, it is characterised in that including：With human body head profile
Body mould body, the body mould body is internally provided with least one dismountable replacement module；
Dismountable replacement module is selected from brain tumor analog module, the image co-registration degree test module of PET/MR, PET/
One or more in the correction for attenuation test module of MR, PET performance parameter tests module or MRI performance parameter test modules.
2. the PET/MR image quality of apery head according to claim 1 detects body mould, it is characterised in that described removable
The replacement module for unloading is located at the brain localization of the top inside body mould body.
3. the PET/MR image quality of apery head according to claim 1 detects body mould, it is characterised in that the brain
Tumour analog module is hollow ball structure；Tracer is perfused with the hollow ball structure.
4. the PET/MR image quality of apery head according to claim 1 detects body mould, it is characterised in that the PET/
The image co-registration degree test module of MR includes：At least one in hollow cylinder, hollow ball or square；
Tracer is filled with the hollow ball or square；
Various sizes of solid source is accommodated in the hollow cylinder.
5. the PET/MR image quality of apery head according to claim 1 detects body mould, it is characterised in that the PET/
The correction for attenuation test module of MR, including：At least one hollow cylinder plug-in unit, the hollow cylinder plug-in unit is divided into two parts, one
Part is located to be had in human body head outline body mould body, and it is external that another part is located at body calligraphy or painting model.
6. the PET/MR image quality of apery head according to claim 1 and 2 detects body mould, it is characterised in that described
PET performance parameter test modules, are made up of the cylinder of some groups of different-diameters；
The cylinder is hollow or solid construction.
7. the PET/MR image quality of apery head according to claim 1 and 2 detects body mould, it is characterised in that described
MRI performance parameter test modules, including：MRI high-contrasts module resolution and MRI low contrast resolution modules.
8. the PET/MR image quality of apery head according to claim 7 detects body mould, it is characterised in that the MRI
High-contrast module resolution is made up of the circular hole of some groups of different-diameters, is not being made an uproar seriously for testing measurement imaging system
To the resolution capability of object minimum details during sound；
The MRI low contrast resolutions module is made up of the circular hole of some groups of different-diameters for radially distributing；Each group
Circular hole diameter it is identical, the depth of each group of circular hole is different.
9. the PET/MR image quality of the apery head described in any one of claim 1-8 detects the preparation method of body mould, and it is special
Levy and be, step is as follows：
(1) CT scan data according to human body head builds the body mould body with human body head profile；
(2) at least one dismountable replacement module is set in the inside of the body mould body for building.
10. the PET/MR image quality of the apery head described in any one of claim 1-8 detects body mould in PET/MR imagers
Quality control, the purposes found in the optimal sweep parameter of PET/MR imagers, demonstration lesson and/or the screening of tracer.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710169602.3A CN106901765A (en) | 2017-03-21 | 2017-03-21 | A kind of PET/MR image quality detection body mould of apery head and preparation method thereof |
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| CN201710169602.3A CN106901765A (en) | 2017-03-21 | 2017-03-21 | A kind of PET/MR image quality detection body mould of apery head and preparation method thereof |
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| CN108847105A (en) * | 2018-03-15 | 2018-11-20 | 江苏舟可医疗器械科技有限公司 | A kind of neurosurgery navigation emulational head model |
| CN109669151A (en) * | 2019-02-12 | 2019-04-23 | 泰山医学院 | The quality control volume mould and evaluation method of Magnetic Resonance Perfusion Imaging of Arterial Spin Labeling |
| WO2021000861A1 (en) * | 2019-07-02 | 2021-01-07 | 西安大医集团股份有限公司 | Simulated phantom |
| CN115489122A (en) * | 2022-07-27 | 2022-12-20 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | Method and system for constructing quality control simulation model of magnetic resonance radiotherapy machine |
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| CN108847105A (en) * | 2018-03-15 | 2018-11-20 | 江苏舟可医疗器械科技有限公司 | A kind of neurosurgery navigation emulational head model |
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