KR101856352B1 - The phantom for medical image length measurement standard based on unit block type - Google Patents

Abstract

The present invention relates to a phantom for medical image length measurement standard based on a unit block form. Specifically, the present invention can be assembled on the basis of a unit block shape. Therefore, by measuring lengths and angles of various sections in an acquired image, a video length measurement standard Phantom. In a medical phantom, which is a model modeling at least a part of a human body by using a plurality of unit blocks related to an example of the present invention, the plurality of unit blocks include an identifiable ball An inserted first unit block; A second unit block having a plurality of ridges formed at an upper end thereof and a lower end coupled to an upper end of the first unit block; And a third unit block having a plurality of troughs engageable with the plurality of troughs at a lower end thereof and having an upper end coupled to a lower end of the first unit block; Wherein a shape of the medical phantom is determined according to a combination of the first unit block, the second unit block, and the third unit block, and the image for the medical phantom is obtained A first distance between the first ball and the second ball included in the plurality of first unit blocks and a second distance between the first ball and the second ball in the image, A treatment plan may be possible.

Description

[0001] The present invention relates to a phantom for a medical image length measurement standard based on a unit block type,

The present invention relates to a phantom for medical image length measurement standard based on a unit block form. Specifically, since the present invention can be assembled on the basis of a unit block shape, it is possible to measure the length and angle of various sections in the acquired image, and thereby measure the image length, which can provide measurement uncertainty due to the difference between the image length and the actual length It is about standard phantoms.

MEDICAL PHANTOM is a model that simulates the physical properties of whole or part of the human body. It is used for various purposes such as performance evaluation of diagnostic and therapeutic instruments, medical image quality evaluation, dose measurement, interventional procedure training and evaluation. do.

Especially, since the physical mechanism of image acquisition differs according to the image diagnostic apparatus and the size and shape of the image diagnostic apparatus are different, there exist phantoms having various types and properties at present.

In other words, the medical phantom must be manufactured in various forms to suit various sizes and shapes of the imaging diagnostic devices, and the phantom is limited to the characteristics of the device.

Furthermore, in order to make a phantom in a shape similar to the human body, it must be made in a size similar to that of a human body, and since the medium is inserted therein, the weight is heavy and the operation is difficult.

The human body can be modeled in many ways, especially when simulating the human body, with a combination of voxel units, which are small volumes.

In other words, various combinations of voxels can simulate the tissues and organs of the human body.

As a result, the phantom can be constructed in units of voxels by applying the above concept to the medical phantom, and the phantom using the LEGO block is the best implementation of the phantom.

Previously, bricks, which are unit blocks of LEGO, were combined to form a certain type of phantom, which was then used to evaluate the performance of imaging devices.

However, in the case of a phantom using a LEGO block, since the inside of the block is an empty space, there is a disadvantage that the block must be assembled and then imaged in a certain size container.

That is, although it is possible to assemble in various forms using blocks, there is a disadvantage in that it is inevitable to put a block in a container containing a signal source in order to generate a signal source necessary for imaging.

Furthermore, there is also a problem that a medium having a specific physical property is required inside the block even for image evaluation and dose measurement.

As a result, in the case of the phantom using the LEGO block, the degree of freedom of the block is limited according to the size and shape of the container, and the same problem as that of the phantom widely used in the past is obtained.

Also, the most important disadvantage of LEGO BLOCK is that it is not designed for medical phantom, so there are many limitations in using size, shape and function for medical use.

In addition, since the Lego form has a ridge and a furrow in the block, when the image is simply combined, it has a complicated shape, which is very disadvantageous to the medical utilization of the image.

Particularly, the complexity of LEGOs with a small physical size is very large, and when the physical size is relatively large, there is a disadvantage in that it is disadvantageous in detailed simulation of the human body characteristics.

In particular, the accuracy of planning and the accuracy of actual treatment may vary depending on the difference between the length and the actual length of the image, and a method of determining the difference between the length and the actual length of the image generated in response to various forms Therefore, there is a need for a solution to this problem.

Korean Intellectual Property Office Registration No. 10-0739187

SUMMARY OF THE INVENTION It is an object of the present invention to provide a phantom for a medical image length measurement standard based on a unit block type.

Specifically, since the present invention can be assembled on the basis of the unit block shape, it is possible to measure the length and angle of various sections in the acquired image, and thereby obtain a video length that can provide the measurement uncertainty due to the difference between the video length and the actual length It is an object of the present invention to provide a phantom for a measurement standard to a user.

It is to be understood that both the foregoing general description and the following detailed description of the present invention are exemplary and explanatory and are not intended to limit the invention to the precise form disclosed. It can be understood.

In a medical phantom, which is a model in which at least a part of a human body is modeled by using a plurality of unit blocks related to an example of the present invention for realizing the above-mentioned problems, A first unit block into which an identifiable ball is inserted; A second unit block having a plurality of ridges formed at an upper end thereof and a lower end coupled to an upper end of the first unit block; And a third unit block having a plurality of troughs engageable with the plurality of troughs at a lower end thereof and having an upper end coupled to a lower end of the first unit block; Wherein a shape of the medical phantom is determined according to a combination of the first unit block, the second unit block, and the third unit block, and the image for the medical phantom is obtained A first distance between the first ball and the second ball included in the plurality of first unit blocks and a second distance between the first ball and the second ball in the image, A treatment plan may be possible.

In addition, a treatment plan for the human body may be possible by additionally using a first angle difference between the first ball and the second ball and a second angle difference between the first ball and the second ball in the image.

The plurality of balls included in the plurality of first unit blocks may have a spherical shape, and the plurality of balls may be formed of gold, tungsten, copper, iron, and aluminum At least one can be made.

The plurality of troughs are formed in a cylindrical shape protruding from the upper end of the second unit block, and the plurality of troughs are formed into a cylindrical shape recessed at the lower end of the third unit block so as to be able to engage with the plurality of troughs .

The second unit block and the third unit block are plural, and at least one of a plurality of ridges of the plurality of second unit blocks and a plurality of ridges of the plurality of third unit blocks are combined to form the shape of the medical phantom Can be determined.

In addition, the medium included in the first unit block, the second unit block, and the third unit block may be a Gd-based medium, an iron oxide-based medium, or a Gd-based medium capable of giving signals necessary for magnetic resonance imaging, such as CuSO4, MnCl2, NiCl2, Gel-type media.

The medium included in the first unit block, the second unit block and the third unit block may include water, Iodine, Barium, CaCO 3, Paraffin, and Adipose capable of image evaluation in X-ray computed tomography have.

The medium included in the first unit block, the second unit block, and the third unit block may include positron-emmitting isotopes and gamma-emitting isotopes, which are signal sources of PET and SPECT, which are nuclear medicine imaging devices.

In addition, the medical phantom determined according to the combination of the first unit block, the second unit block, and the third unit block can be used for multiple purposes, and can be connected to multiple imaging devices to support multiple imaging.

Meanwhile, in another example of the present invention for realizing the above-described problems, an imaging apparatus using the medical phantom described above may be proposed.

On the other hand, a medical phantom (Model PHANTOM) modeling at least a part of a human body using a plurality of unit blocks related to another example of the present invention for realizing the above- A method for establishing a plan, the plurality of unit blocks comprising: a first unit block having an identifiable ball inserted therein; A second unit block having a plurality of ridges formed at an upper end thereof and a lower end coupled to an upper end of the first unit block; And a third unit block having a plurality of troughs engageable with the plurality of troughs at a lower end thereof and having an upper end coupled to a lower end of the first unit block; Wherein the shape of the medical phantom is determined according to the combination of the first unit block, the second unit block, and the third unit block, and the image for the medical phantom is obtained A first distance between the first ball and the second ball included in the plurality of first unit blocks and a second distance between the first ball and the second ball in the image, A treatment plan may be possible.

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned problems, and it is an object of the present invention to provide a phantom for a medical image length measurement standard based on a unit block type to a user.

Specifically, the present invention can provide a unit block having a shape and structure capable of filling a unit block constituting a phantom and a medium necessary for imaging the inside of the unit block, and capable of image quality evaluation, dose measurement and interventional treatment training have.

Unlike a conventional single image, a single purpose heavy, and difficult to operate phantom, the block-based phantom according to the present invention can be combined in various forms according to a combination of blocks, and can be used for multiple images and multiple purposes, Is very easy to mass-produce, and it is very economical because it can be used in various video devices.

In addition, since the present invention can be assembled on the basis of the unit block shape, the length and angle of the various sections are measured on the acquired image, so that the image length that can provide a standard for the difference between the image length and the actual length A phantom for the measurement standard can be provided to the user.

According to the present invention, the difference between the length and the actual length of the image generated in response to the various types of images can be quickly determined based on the difference between the length of the image and the actual length of the image. .

It should be understood, however, that the effects obtained by the present invention are not limited to the above-mentioned effects, and other effects not mentioned may be clearly understood by those skilled in the art to which the present invention belongs It will be possible.

BRIEF DESCRIPTION OF THE DRAWINGS The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate a preferred embodiment of the invention and, together with the description, serve to provide a further understanding of the technical idea of the invention, It should not be construed as limited.
Fig. 1 shows an example of a phantom for measuring the dose of radiation according to the present invention.
2 shows an exploded perspective view of the phantom for measuring the radiation dose described in Fig. 1
Figure 3 illustrates various types of medical phantoms associated with the present invention.
4 shows a specific example of another kind of medical phantom related to the present invention.
FIG. 5 illustrates a specific example of modeling a human body in a three-dimensional form with reference to the present invention.
6 shows a specific example of modeling a human body using a Lego block.
FIG. 7 shows another specific example of modeling a human body using a Lego block.
Figure 8 shows a specific example of an MRI T2 image obtained by filling an Oxford block with water, in the context of the present invention.
9 shows a basic form of a unit block proposed by the present invention.
10 to 12 show an example of an application form of a unit block proposed by the present invention.
FIG. 13 shows a form of a stem block phantom proposed by the present invention.
FIG. 14 shows a concrete form of a stem block phantom applied to a multipurpose multiple image in connection with the present invention.
FIGS. 15 to 16 illustrate concrete forms of a QA / AC module to which a stem block phantom applied to a multi-purpose multiple image is applied according to the present invention.
17A is an example of a system for testing phantom shape, material type, size, and the like through computer simulation, and FIG. 17B shows attenuation characteristics for each of the tested materials with respect to X-ray energy.
Fig. 18 shows an example of a unit block phantom including a ball proposed by the present invention.
FIG. 19 shows a concrete example of combining a unit block including the ball described in FIG. 18 with a unit block.
FIG. 20 shows a specific example of the cross section of the combined phantom described in FIG. 19.
FIG. 21 shows a specific example in which the coupled phantoms explained in FIG. 19 are connected in series.
FIG. 22 shows a concrete state in which a difference between a length and an actual length in an image is determined through a unit block phantom including a ball proposed by the present invention.

Hereinafter, a preferred embodiment of the present invention will be described with reference to the drawings. In addition, the embodiment described below does not unduly limit the contents of the present invention described in the claims, and the entire configuration described in this embodiment is not necessarily essential as the solution means of the present invention.

Phantom refers to a model used as a substitute for biological system research, such as the distribution of electromagnetic waves in the human body and the specific absorption rate (SAR) analysis and analysis of human tissues.

At this time, the quantitative evaluation of the electromagnetic waves received by the human body is performed by the specific absorption rate. Since it is difficult to actually measure the electromagnetic waves, the so-called phantom which is the same as the human body is made, Estimation by analysis, and the like.

It is necessary that the phantom has a shape similar to that of the human tissue structure and has a relative dielectric constant ε, a conductivity σ, and a density ρ of the human tissue at each measurement frequency.

Typically, a phantom can be used as a model instead of the human body to determine the amount of radiation the human body receives, which means an object used to simulate the attenuation, scattering, or distribution of radioactive material in an object. .

The medical phantom is a model that simulates the physical properties of whole or part of the human body. It can be used for a variety of purposes, such as performance evaluation of diagnostic and therapeutic devices, medical image quality evaluation, dose measurement, .

Fig. 1 shows an example of a phantom for measuring a radiation dose related to the present invention, and Fig. 2 shows an example of an exploded perspective view of a phantom for measuring a radiation dose described in Fig.

FIG. 1 is a diagram for explaining an example of using a phantom for measuring a radiation dose according to an embodiment of the present invention. In this embodiment, a linear accelerator 11 is taken as an example of a radiation emitting apparatus.

Referring to FIG. 1, it can be seen that the phantom 21 according to the present embodiment is located in the vertical lower portion of the radiation emitting portion 17 with the treatment table 19 being raised. The treatment table 19 is a set of linear accelerators 11 and is a bed on which a patient to be treated lies.

The linear accelerator 11 is composed of a main body 13 and a rotary gantry 15 rotatably installed on the main body 13.

A high voltage generator or a microwave generator is installed in the main body 13 and an acceleration tube for accelerating electrons and a device such as a magnetic field generator and a radiation emitting portion 17 are installed inside the rotary gantry 15 Respectively. The radiation output from the radiation emitting portion 17 is irradiated to the tumor of the patient lying on the treatment table 19. [

The phantom 21 according to the present embodiment receives the radiation irradiated downward from the radiation emitting portion 17 while being set on the vertical lower portion of the radiation emitting portion 17, .

The phantom 21 includes at least one base plate 27 and a template accommodating plate 29 in which various types of embedding bodies 23 are embedded as required and a plurality of flat plate plates 31, A TLD mounting plate (hereinafter referred to as TLD mounting plate) 33 (FIG. 2), an ion chamber mounting plate (reference numeral 39 in FIG. 3), and the like.

The combination of the above-described various components may vary depending on the case, and may have the lamination structure shown in, for example, FIG. 4 to FIG.

Reference numeral 51 denotes an X-ray film. The X-ray film 51 is a target of radiation passing through the wedge plate 25, the flat plate 31, and the photoreceptor plate 29 in order, and the energy level of the radiation reaching the surface is expressed.

Consequently, the X-ray film 51 is a radiation dose measuring unit for measuring a dose (at a corresponding depth) of the radiation irradiated from the radiation emitting portion 17. [ In addition to the X-ray film 51, a TLD mounting plate 33 and a thermoluminescent dosimeter (hereinafter referred to as TLD) (refer to FIG. 2) 53, an ion chamber mounting plate, An ion chamber is further included.

The radiation dose measuring unit has a purpose of measuring a dose of radiation at a depth where the radiation dose measuring unit is located.

The depth at which the radiation dose measuring part is located depends on the combination example described above. Also, what kinds of the simulations 23 are located on the upper part of the radiation dose measuring part, and whether the simulator is not positioned or not is different depending on the case.

2 is an exploded perspective view showing one example of a combination of phantoms for measuring a radiation dose according to an embodiment of the present invention.

2, the phantom 21 for measuring radiation dose according to one combination example includes a base plate 27 having a rectangular plate shape with a predetermined thickness, a TLD (Charge Coupled Device) stacked on the base plate 27, A mounting plate 33 and a mold receiving plate 29, a flat plate 31 and a wedge plate 25 which are sequentially stacked on the TLD mounting plate 33, (35).

The base plate 27 horizontally supports the TLD mounting plate 33 at a predetermined height from the treatment table 19 while being placed on the treatment table 19 as shown in Fig. The base plate 27 adjusts the separation distance of the radiation dose measuring unit with respect to the radiation emitting unit 17.

For example, the thickness of the base plate 27 may be increased or the number of the base plates 27 may be increased to narrow the distance of the radiation dose measuring unit relative to the radiation emitting unit 17. [

A female screw hole 27a is formed in each of the four corners of the base plate 27. The female screw hole 27a has a male threaded portion formed on the inner circumferential surface of the female screw hole 27a and engages with the male screw portion 35a at the lower end of the stationary rod 35. [ The fixing rod 35 is vertically extended in a state of being coupled to the female screw hole 27a, and closely fixes the respective components.

The TLD mounting plate 33 is a rectangular acrylic plate having a predetermined thickness and has five TLD receiving holes 33b extending horizontally therein. The TLD receiving hole 33b has a predetermined diameter and is parallel and both ends thereof are open to the outside. It goes without saying that the number of the TLD receiving holes 33b may vary depending on the case.

For reference, acrylic has a tissue density corresponding to the density of normal tissue in the body.

The TLD 53 is inserted into the TLD receiving hole 33b. As is known in the art, a TLD is a dosimeter made of a material having thermal fluorescence properties, and it can be manufactured in the form of chips or powder. In powder form it is sealed in a cylindrical capsule.

In this embodiment, the capsule type TLD 53 is used. That is, the capsule type TLD 53 is inserted into the TLD receiving hole 33b and then pushed to the center portion, for example. In particular, the TLD 53 may be inserted into one TLD receiving hole 33b, or may be applied only to the selected TLD receiving hole 33b. The TLD 53 receives the radiation irradiated from the upper part in a state in which the TLD is accommodated in the TLD receiving hole 33b and is capable of quantitatively evaluating the amount of radiation irradiated through the TLD reader (not shown) do.

A mold receiving plate 29 is provided on the TLD mounting plate 33. The impression receiving plate 29 is a hexahedral acrylic block having through holes 29a perpendicular to four corners, and includes two spaces 29b and 29c therein.

The space portions 29b and 29c are horizontally extended in a state of being parallel to each other and are square holes whose both ends are open to the outside. The cross-sectional shape and size of the space portions 29b and 29c may vary depending on the case.

Basically, the space portions 29b and 29c may be empty according to the object to be simulated in the body, or may be filled with the molding body 23. For example, when the empty space such as the mouth is simulated, the space portion 29c is empty. In addition, when the lungs are simulated, a cork known to have similar lung and tissue densities is inserted. When bone is simulated, Teflon, which is similar in tissue density to bone, is inserted. The copying bodies 23 may be formed in the form of a block or in the form of a thin plate, and may be laminated as required. The imprint receiving plate 29 may not be used as occasion demands.

The plate plate 31 located at the top of the impression receiving plate 29 is a rectangular acrylic plate having various thicknesses.

The flat plate 31 serves to adjust the separation distance of the target with respect to the radiation emitting portion 17. Therefore, the position of the flat plate 31 and the number of sheets to be used can be changed as needed. For example, between the base plate 27 and the TLD mounting plate 33 and may be provided between the wedge plate 25 and the imprint receiving plate 29 as shown. Needless to say, through holes 31a are also formed in the four corners of the flat plate 31.

On the other hand, the wedge plate 25 is an acrylic member having a side shape of a right triangle. The wedge plate 25 has a horizontal bottom surface and an inclined surface 25b inclined at a predetermined angle with respect to the bottom surface. The inclination angle of the inclined surface 25b is preferably about 15 to 30 degrees.

Basically, the wedge plate 25 serves to linearly grasp the extent of radiation reaching a target having a different depth. For example, when the wedge plate 25 is irradiated vertically with the X-ray film placed on the lower portion of the wedge plate 25, the energy of the wedge plate 25 (the thickness of the wedge plate is linear As the radiation passes through the X-ray film downward, the radiation of the smaller and smaller energy is reflected on the X-ray film, thereby obtaining the attenuation rate information of the radiation with respect to the thickness of the acrylic. As the radiation passes through the thicker portion of the wedge plate 25, it decays less when the attenuation rate is large and passes through the relatively thin portion.

A through hole 25a is also formed in the four corners of the wedge plate 25.

The fixing rod 35 vertically supports the respective components on the top of the base plate 27 (in this case, the combination examples of the respective components may be different), the TLD mounting plate 33, 29a, 31a, 25a of the flat plate 29 and the flat plate 31 and the wedge plate 25 so that the male threaded portion 35a at the lower end thereof passes through the female screw hole 27a of the base plate 27, Respectively.

Reference numeral 36 denotes a nut which tightly connects the components to each other by engaging with the male screw portion 35a at the upper end of the stationary rod 35. [

1 and 2, it is assumed that the phantom according to the present invention is for radiation measurement, but it is obvious that the present invention is not limited thereto and can be applied to various medical purposes.

3 illustrates various types of medical phantoms related to the present invention.

As shown in FIG. 3, since the physical mechanism of image acquisition differs according to the image diagnostic apparatus and the size and shape of the image diagnostic apparatus are different, there are presently various types and properties of phantoms.

4 shows a specific example of another kind of medical phantom related to the present invention.

4 (a) to 4 (d), the medical phantom can only be manufactured in various forms suitable for various sizes and shapes of the image diagnostic device. As a result, the phantom is limited to the characteristics of the device I can not help it.

Furthermore, in order to make a phantom in a shape similar to the human body, it must be made in a size similar to that of a human body, and since the medium is inserted therein, the weight is heavy and the operation is difficult.

The human body can be modeled in many ways, especially when simulating the human body, with a combination of voxel units, which are small volumes.

In other words, various combinations of voxels can simulate the tissues and organs of the human body.

FIG. 5 illustrates a specific example of modeling a human body in a three-dimensional form with reference to the present invention.

5 (a) to 5 (d), the phantom can be constructed in units of voxels by applying the above concept to the medical phantom, and the phantom using the lego block is the best implementation thereof.

FIG. 6 shows a specific example of modeling a human body using a LEGO block, FIG. 7 shows another specific example of modeling a human body using a LEGO block, and FIG. 8 shows, in conjunction with the present invention, FIG. 2 shows a specific example of an MRI T2 image obtained by filling water with water.

As shown in FIGS. 6 (a) to 8 (b), conventionally, a brick, which is a unit block of LEGO, is combined to form a certain type of phantom, which is then used for performance evaluation of an imaging diagnostic apparatus.

However, in the case of a phantom using a LEGO block, since the inside of the block is an empty space, there is a disadvantage that the block must be assembled and then imaged in a certain size container.

That is, although it is possible to assemble in various forms using blocks, there is a disadvantage in that it is inevitable to put a block in a container containing a signal source in order to generate a signal source necessary for imaging.

Furthermore, there is also a problem that a medium having a specific physical property is required inside the block even for image evaluation and dose measurement.

As a result, in the case of the phantom using the LEGO block, the degree of freedom of the block is limited according to the size and shape of the container, and the same problem as that of the phantom widely used in the past is obtained.

Also, the most important disadvantage of LEGO BLOCK is that it is not designed for medical phantom, so there are many limitations in using size, shape and function for medical use.

In addition, since the Lego form has a ridge and a furrow in the block, when the image is simply combined, it has a complicated shape, which is very disadvantageous to the medical utilization of the image.

In particular, the complexity of combining Lego with a small physical size becomes very large, and when the physical size is relatively large, there is a disadvantage in that it is disadvantageous in detailed simulation of human characteristics.

Accordingly, the present invention provides a multimodule medical phantom using a unit block, a unit block, and a control method thereof for a multi-purpose multi-image. More particularly, the present invention relates to a method of producing a unit block having a shape and a structure capable of filling a unit block constituting a phantom and a medium required for imaging the inside of the unit block and performing image quality evaluation, dose measurement and interventional treatment, ≪ / RTI >

That is, the unit block proposed by the present invention can be manufactured in the form of a hexahedron so that a medium can be inserted therein.

The basic form of a unit block according to the present invention is a unit block consisting of only a hexahedron, and an application form may be a structure in which a block (male) is formed at the top of the block and a groove (female) is formed at the bottom of the block.

The basic form and the application form unit block proposed by the present invention can be composed of various shapes and sizes in various combinations and combinations.

At this time, the unit block may contain media such as CuSO 4, MnCl 2, and NiCl 2, which are signals required for magnetic resonance imaging, and Gd-series, iron oxide-based, and gel-type media capable of providing a contrast effect.

In addition, the unit block may contain media such as water, Iodine, Barium, CaCO3, Paraffin, and Adipose that can perform image evaluation in X-ray computed tomography. Positron-emmittingisotopes And gamma-emittingisotopes.

In particular, multiple imaging of multiple imaging devices as well as imaging in a single imaging device are possible through multiple combinations of unit blocks.

In addition, the block-based phantom constructed in this manner can be used for dose evaluation of radiotherapy and temperature measurement of heat treatment.

In addition, the image quality evaluation module can be added inside the unit block to evaluate the spatial resolution, contrast resolution, signal-to-noise ratio, uniformity, position and accuracy of section selection, and geometric accuracy through a combination of unit blocks.

In particular, it can be used with the phantom used in the conventional image quality evaluation, so that it is possible to acquire the quality information on the photographing area that the existing phantom could not image.

9 shows a basic form of a unit block proposed by the present invention.

9 is a block diagram of a basic unit block according to the present invention. In FIG. 9, a denotes a block (phantom) length, b denotes a block (phantom) width, c denotes a block , And d is the height of the block (cap).

The inside of the unit block according to the present invention shown in FIG. 9 is an empty space, and is formed in a structure in which a medium suitable for medical image purposes is attached to the inside of the unit block.

The side of the unit block according to the present invention has two holes, so that the medium can be injected through one hole, and the medium injected into the other holes and the inner air can be escaped, have.

On the other hand, Figs. 10 to 12 show an example of an application form of a unit block proposed by the present invention.

10 to 12 show the contents of the configuration of the application type unit block.

In FIGS. 10 to 12, 111 denotes the width of the socket, 112 denotes the height of the socket, 121 denotes the thickness of the container, 122 denotes the phantom fluid, and 123 denotes the inlet of the phantom fluid 124 denotes the height of the block (phantom), 125 denotes the width of the block (phantom) inlet, and 126 denotes the width of the exit of the block (phantom).

Reference numeral 131 denotes the width of the outlet of the cap, 132 denotes the width of the inlet of the cap, 133 denotes the height of the cap, 134 denotes the fan tub fluid, 135 Denotes the width of the socket, 136 denotes the height of the socket, and 137 denotes the container material.

Referring to FIGS. 10 to 12, the application type unit block is composed of a ridge and a groove, and can be combined and disassembled between unit blocks, and can be assembled in various forms.

The ridge area is a cube shape, and the ridge area is constructed so that the ridge area cube can be accurately attached.

In addition, the unit block is an empty space, and it is structured such that a medium suitable for a purpose can be attached and sealed inside.

In addition, there are two holes on the side except the unit block and the furrow, so that the medium can be injected through one hole, and the medium injected into the other hole and the inside air can escape, .

That is, the block according to the present invention is an application block having a base (unit) consisting of only a hexahedron and an application form having a ridge (nucleus) at the top of the block and a trough (female) at the bottom of the block. And the like.

Accordingly, the basic form and the application form unit block proposed by the present invention can be configured in various shapes and sizes in various combinations and combinations.

At this time, the unit block may contain media such as CuSO 4, MnCl 2, and NiCl 2, which are signals required for magnetic resonance imaging, and Gd-series, iron oxide-based, and gel-type media capable of providing a contrast effect.

In addition, the unit block may contain media such as water, Iodine, Barium, CaCO3, Paraffin, and Adipose that can perform image evaluation in X-ray computed tomography. Positron-emmittingisotopes And gamma-emittingisotopes.

In particular, multiple imaging of multiple imaging devices as well as imaging in a single imaging device are possible through multiple combinations of unit blocks.

Meanwhile, FIG. 13 shows a form of a stem block phantom proposed by the present invention.

FIG. 13 shows the contents of signals such as CuSO.sub.4, MnCl.sub.2, and NiCl.sub.2 necessary for magnetic resonance imaging in the unit block, and Gd series, iron oxide series, gel type, and the like capable of providing a contrast effect.

13, a medium such as water, Iodine, Barium, CaCO3, Paraffin, and Adipose capable of evaluating an image in an X-ray computed tomography (CT) can be inserted. Positron-emmitting isotopes and gamma-emitting isotopes.

FIG. 14 shows a concrete form of a stem block phantom applied to a multi-purpose multi-image according to the present invention.

That is, Figure 14 illustrates a basic scheme that enables multiple imaging in multiple imaging devices as well as imaging in a single imaging device through multiple combinations of unit blocks.

The block-based phantom constructed as shown in FIG. 14 can be used not only for a multi-imaging device but also for dose evaluation of radiation therapy and temperature measurement of heat treatment.

15 to 16 illustrate a specific form of a QA / AC Module to which a stem block phantom applied to a multi-objective multiple image is applied according to the present invention.

15 to 16, the image quality evaluation module is added to the unit block to evaluate the spatial resolution, contrast resolution, signal-to-noise ratio, uniformity, position and accuracy of the section selection, and geometric accuracy through a combination of unit blocks As shown in FIG.

15 to 16, it is possible to acquire quality information on a photographing region that has not been imaged by an existing phantom by using the same as a phantom used in an existing image quality evaluation.

Unlike the conventional single-image, single-purpose, heavy-duty, and difficult-to-operate phantom, the block-based phantom can be combined in various forms according to the combination of blocks, It becomes possible.

In particular, the unit block is very economical because it is very easy to mass-produce and can be used in various image devices.

In addition, performance evaluation, quality control, and dose measurement of imaging devices are very important factors in the medical field, and because they can be used in all clinical institutions due to the characteristics of blocks that can be combined in various forms, they are widely used, Can be provided to the user.

On the other hand, according to the difference between the length and the actual length of the image, the accuracy of the plan established beforehand and the accuracy of the actual treatment may vary. A method of determining the difference between the image length and the actual length, There is no problem.

Therefore, since the present invention can be assembled on the basis of the unit block shape described with reference to Figs. 1 to 16, it is possible to measure the length and angle of various sections in the acquired image, We propose a phantom for video length measurement standard that can be presented.

That is, in the present invention, after inserting a ball that can be identified in a unit block and combining a plurality of unit blocks in various forms, an actual length between the plurality of balls and a length between a plurality of balls in the image for the plurality of unit blocks The differences are compared, and the corrected values are applied to the actual treatment plan and treatment.

Therefore, according to the present invention, it is possible to know in advance a correction value for a length difference between specific points in a phantom actually produced and a length difference between specific points seen in an image, so that a more accurate diagnosis and treatment plan, .

In addition, since it is possible to assemble based on the unit block type described above with reference to Figs. 1 to 16, it is possible to produce phantoms corresponding to various cases regardless of the object type, The correction value for the length difference at the point of time is easily known.

The inventors conducted computer simulation of the shape, material type, size, and the like of the phantom to determine the material of the ball applied to the present invention.

In addition, it is also possible to establish a plan using not only the length difference but also the angular difference between the actual balls and the angular difference in the image.

Ultimately, the phantom can produce more consistent results in medical imaging evaluation and optimization than the human body with subjective subjective quantities, and it enables accurate diagnosis and treatment based on this.

The present invention selects unit blocks in the form of phantom with integrated diversity for consistency and standardization.

In addition, it is configured in a columnar shape so that it can be used not only in simple X-ray but also in X-ray computed tomography apparatus, and inserts a proper metal sphere according to the purpose in order to obtain a high contrast image.

Since it is a unit block type and can be assembled, it is possible to measure the length and angle of various metal sections in the obtained image.

Medical imaging has become an essential element in the diagnosis and treatment of modern medicine.

For medical diagnosis, treatment plan, and therapeutic effect tracking based on medical images, measures such as measuring lesion size or measuring the length of anatomical organs are being performed.

However, there is no study of the uncertainty between the measured value and the actual lesion size in medical images.

As the paradigm shifts from qualitative to quantitative evaluation of medical images, it is urgent to establish measurement standards with traceability in medical image based measurement.

The present invention relates to a phantom for length measurement standard configured in the form of a modular unit block in order to secure traceability in the measurement of the length of a medical image.

FIG. 17A is an example of a system for testing phantom shape, material type, size, and the like through computer simulation, and FIG. 17B shows attenuation characteristic results for each of the tested materials. FIG.

The present inventor tried to design a module based on computer simulation, and tried to design a module by testing a phantom shape, material type, and size through computer simulation.

17A, a beam source 2000, a phantom 1000 implemented as a unit including a ball, and a position where light output from the source reaches the phantom 1000 through a predetermined angle is detected A system including a detector 3000 is disclosed.

17B is an attenuation coefficient of X-ray energy of each of the tested materials through the system of FIG. 17A, and expresses values of gold, tungsten, copper, iron, and aluminum.

In the present invention, it is assumed that the material of the ball is used as tungsten, but the present invention is not limited thereto.

In addition, although the shape of the ball is a sphere, it is assumed herein that the shape of the ball of the present invention is not limited to the spherical shape.

Fig. 18 shows an example of a unit block phantom including a ball proposed by the present invention.

Referring to FIG. 18, the phantom 1100 for the length standard is embodied to include a cylindrical case 1110 and a ball 1120 of tungsten inserted therein.

In addition, the phantom 1100 for the length standard may be implemented in various forms by being connected to the legato-shaped phantom described with reference to Figs. 1 to 16.

19 shows a specific example of combining the unit block with the phantom 1100 for the length standard including the ball described in Fig.

19 (a) to (e), a concrete view is shown in which the unit blocks 1130 are coupled to the upper and lower ends of the phantom 1100 for the middle-length standard.

The phantom 1100 for the standard length standard for the gown includes a tungsten ball 1120 inside the outer case 1110.

FIG. 20 shows a specific example of the cross section of the combined phantom described in FIG. 19.

Referring to FIG. 20 (a), a combined unit phantom illustrated in FIGS. 19 (a) to 19 (e) is cut and a unit block 1130 at the upper and lower ends is shown.

20B, the upper and lower unit blocks 1130 and the cylindrical case 1110 of the phantom 1100 for the standard of length are shown together.

Referring to FIGS. 20C and 20D, the unit block 1130 at the upper and lower ends, the cylindrical case 1110 of the phantom 1100 for the standard of length, the cylindrical case 1110, The ball 1120 of tungsten is expressed.

It is also possible that the phantom 1100 for the length standard described in FIGS. 19 and 20 and the unit phantom connected to the Lego-shaped phantom are once again connected to each other.

For example, when a legato-shaped phantom having a plurality of projections is connected to the top of the phantom 1100 for the length standard and a legato-shaped phantom having a plurality of grooves is connected at the bottom, a phantom 1100 ) And the Lego-shaped phantom are connected to each other, the upper ends of the unit phantoms connected to each other are inserted into the lower ends of the other unit phantoms.

FIG. 21 shows a specific example in which the coupled phantoms explained in FIG. 19 are connected in series.

Referring to FIG. 21, a legato-shaped phantom is connected in series to a phantom 1100 for four length standards, thereby achieving a top-shaped overall phantom shape.

In this state, the user can obtain the actual distance difference between the first ball and the second ball among the plurality of manufactured balls 1120 of the entire phantom shape.

In addition, distance adjustment between the first ball and the second ball displayed on the image obtained through the entire phantom shape can be obtained.

Thereafter, by comparing the actual distance difference and the distance difference in the image to obtain the correction value, the diagnosis and treatment plan and treatment are performed according to the ratio, thereby making it possible to perform more accurate diagnosis, treatment, and the like.

Even if a correction plan is established in the dentistry and orthodontic treatment is carried out, accurate progress can be made by the difference in length between the image and the actual length.

For example, the user may arbitrarily designate the first ball and the second ball among the plurality of balls 1120 displayed through the display unit, and grasp the length between the first ball and the second ball on the display unit.

The user can also be used in treatment planning and treatment by obtaining the actual distance difference between the first ball and the second ball in the overall phantom shape actually produced and comparing the difference with the distance difference on the display portion.

FIG. 22 shows a concrete state in which a difference between a length and an actual length in an image is determined through a unit block phantom including a ball proposed by the present invention.

Referring to FIG. 22 (a), phantom acquisition images and software image point (red) images of different diameters are shown.

22 (b) and 22 (c) show specific examples of the simulated image and the experimental image (0.9 mm) enlarged, respectively.

Therefore, the length difference in the image can be grasped and compared with the actual length difference, so that it can be utilized for radiation and orthodontic treatment.

When the above-described configuration of the present invention is applied, unlike a conventional single image, a single purpose heavy and difficult-to-operate phantom, various combinations of blocks can be combined, multiple images can be used for multiple purposes, , The unit block is very easy to mass-produce, and it is very economical because it can be used in various image devices.

In addition, since the present invention can be assembled based on the unit block shape, it is possible to measure a length and an angle of various sections in an acquired image, A standard phantom can be provided to the user.

According to the present invention, the difference between the length and the actual length of the image generated in response to the various types of images can be quickly determined based on the difference between the length of the image and the actual length of the image. .

The present invention can also be embodied as computer-readable codes on a computer-readable recording medium. A computer-readable recording medium includes all kinds of recording apparatuses in which data that can be read by a computer system is stored. Examples of the computer-readable recording medium include a ROM, a RAM, a CD-ROM, a magnetic tape, a floppy disk, an optical data storage device, and the like, and may be implemented in the form of a carrier wave (for example, transmission via the Internet) . The computer readable recording medium may also be distributed over a networked computer system so that computer readable code can be stored and executed in a distributed manner. In addition, functional programs, codes, and code segments for implementing the present invention can be easily inferred by programmers of the technical field to which the present invention belongs.

It should be understood that the above-described apparatus and method are not limited to the configuration and method of the embodiments described above, but the embodiments may be modified so that all or some of the embodiments are selectively combined .

Claims (11)

In a medical phantom, which is a model in which at least a part of a human body is modeled by using a plurality of unit blocks,
The plurality of unit blocks may include:
A first unit block into which an identifiable ball is inserted;
A second unit block having a plurality of ridges formed at an upper end thereof and a lower end coupled to an upper end of the first unit block; And
A third unit block having a plurality of ridges engageable with the plurality of ridges at a lower end thereof and having an upper end engageable with a lower end of the first unit block; ≪ / RTI >
Wherein the first unit block includes a plurality of blocks,
Wherein the shape of the medical phantom is determined according to the combination of the first unit block, the second unit block, and the third unit block,
When an image for the medical phantom is acquired,
A first distance between the first ball and the second ball included in the plurality of first unit blocks and a second distance between the first ball and the second ball in the image, Lt; / RTI >
Wherein a treatment plan for the human body is possible by additionally using a first angle difference between the first ball and the second ball and a second angle difference between the first ball and the second ball in the image,
Wherein the plurality of balls included in the plurality of first unit blocks are spherical,
Wherein the plurality of balls are made of at least one of gold, tungsten, copper, iron, and aluminum. delete delete The method according to claim 1,
Wherein the plurality of ridges are formed in a cylindrical shape protruding from an upper end of the second unit block,
Wherein the plurality of troughs are formed in a cylindrical shape recessed at a lower end of the third unit block so as to be able to engage with the plurality of troughs. 5. The method of claim 4,
The second unit block and the third unit block are plural,
Wherein a shape of the medical phantom is determined by combining at least one of a plurality of ridges of the plurality of second unit blocks and a plurality of ridges of the plurality of third unit blocks. The method according to claim 1,
The medium included in the first unit block, the second unit block, and the third unit block may be any one selected from the group consisting of CuSO4, MnCl2, NiCl2, a Gd series medium capable of generating a contrast effect, an iron oxide series medium, Gt; phantom, < / RTI > The method according to claim 1,
The medium included in at least one of the first unit block, the second unit block and the third unit block includes water, Iodine, Barium, CaCO 3, Paraffin and Adipose capable of image evaluation in X-ray computed tomography Phantom. ≪ / RTI > The method according to claim 1,
The medium included in at least one of the first unit block, the second unit block and the third unit block includes positron-emmitting isotopes and gamma-emitting isotopes which are signal sources of PET and SPECT, Phantom for medical use. The method according to claim 1,
Wherein the medical phantom determined according to the combination of the first unit block, the second unit block and the third unit block is usable for multiple purposes and is capable of supporting multiple imaging by being connected to multiple imaging devices. . An imaging apparatus using a medical phantom according to any one of claims 1 to 8. A method for establishing a treatment plan for a human body using a medical phantom, which is a model modeling at least a part of a human body using a plurality of unit blocks,
The plurality of unit blocks may include:
A first unit block into which an identifiable ball is inserted;
A second unit block having a plurality of ridges formed at an upper end thereof and a lower end coupled to an upper end of the first unit block; And
A third unit block having a plurality of ridges engageable with the plurality of ridges at a lower end thereof and having an upper end engageable with a lower end of the first unit block; / RTI >
The first unit block includes a plurality of first unit blocks,
Wherein the shape of the medical phantom is determined according to the combination of the first unit block, the second unit block, and the third unit block,
When an image for the medical phantom is acquired,
A first distance between the first ball and the second ball included in the plurality of first unit blocks and a second distance between the first ball and the second ball in the image, Lt; / RTI >
Wherein a treatment plan for the human body is possible by additionally using a first angle difference between the first ball and the second ball and a second angle difference between the first ball and the second ball in the image,
Wherein the plurality of balls included in the plurality of first unit blocks are spherical,
Wherein the plurality of balls are made of at least one of gold, tungsten, copper, iron, and aluminum.

Images