CN107074858A - 制备(2s,5r)‑6‑(苄氧基)‑7‑氧代‑1,6‑二氮杂二环[3.2.1]辛烷‑2‑羧酸钠的方法 - Google Patents
制备(2s,5r)‑6‑(苄氧基)‑7‑氧代‑1,6‑二氮杂二环[3.2.1]辛烷‑2‑羧酸钠的方法 Download PDFInfo
- Publication number
- CN107074858A CN107074858A CN201580016887.6A CN201580016887A CN107074858A CN 107074858 A CN107074858 A CN 107074858A CN 201580016887 A CN201580016887 A CN 201580016887A CN 107074858 A CN107074858 A CN 107074858A
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- iii
- case
- benzyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *C([C@@](CCC(C1)N2OCc3ccccc3)N1C2=O)=O Chemical compound *C([C@@](CCC(C1)N2OCc3ccccc3)N1C2=O)=O 0.000 description 1
- VTHYPXYGIBXRQP-QWHCGFSZSA-N N#C[C@H](CC1)NC[C@@H]1NOCc1ccccc1 Chemical compound N#C[C@H](CC1)NC[C@@H]1NOCc1ccccc1 VTHYPXYGIBXRQP-QWHCGFSZSA-N 0.000 description 1
- PHFFTOZKNFUFHJ-CMHHUMAZSA-N OC([C@H](CC1)NC/C1=N\OCc1ccccc1)=O Chemical compound OC([C@H](CC1)NC/C1=N\OCc1ccccc1)=O PHFFTOZKNFUFHJ-CMHHUMAZSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1192/MUM/2014 | 2014-03-29 | ||
| PCT/IB2015/051797 WO2015150941A1 (en) | 2014-03-29 | 2015-03-12 | A process for preparation of sodium (2s, 5r)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate |
| IN1192MU2014 IN2014MU01192A (enExample) | 2014-03-29 | 2015-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107074858A true CN107074858A (zh) | 2017-08-18 |
Family
ID=54239463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580016887.6A Pending CN107074858A (zh) | 2014-03-29 | 2015-03-12 | 制备(2s,5r)‑6‑(苄氧基)‑7‑氧代‑1,6‑二氮杂二环[3.2.1]辛烷‑2‑羧酸钠的方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9688677B1 (enExample) |
| EP (1) | EP3126363A1 (enExample) |
| JP (1) | JP2017508775A (enExample) |
| KR (1) | KR20160138538A (enExample) |
| CN (1) | CN107074858A (enExample) |
| BR (1) | BR112016022437A2 (enExample) |
| IN (1) | IN2014MU01192A (enExample) |
| MX (1) | MX2016012648A (enExample) |
| WO (1) | WO2015150941A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2857401T (pt) * | 2012-05-30 | 2019-11-19 | Meiji Seika Pharma Co Ltd | Novo inibidor de β-lactamase e método para a produção do mesmo |
| HUE051925T2 (hu) | 2013-10-08 | 2021-04-28 | Meiji Seika Pharma Co Ltd | Dizabiciklooktán származék kristályai és diazabiciklooktán származék kristályainak elõállítási eljárása |
| CN107602556B (zh) * | 2017-09-04 | 2020-02-18 | 南京药石科技股份有限公司 | 一种(1s,4s)-2,5-二氮杂二环[2.2.2]辛烷衍生物的中间体及制备方法 |
| CN109678856B (zh) * | 2017-10-18 | 2020-09-25 | 新发药业有限公司 | 一种阿维巴坦中间体的制备方法 |
| WO2021165927A1 (en) * | 2020-02-21 | 2021-08-26 | Wockhardt Bio Ag | 2-cyanopyrroldines, -piperidines or -dazepines as hyperglycemic agents |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013038330A1 (en) * | 2011-09-13 | 2013-03-21 | Wockhardt Limited | Nitrogen containing compounds and their use |
| CN103328476A (zh) * | 2010-12-22 | 2013-09-25 | 明治制果药业株式会社 | 光学活性二氮杂环辛烷衍生物及其制备方法 |
| CA2874279A1 (en) * | 2012-05-30 | 2013-12-05 | Meiji Seika Pharma Co., Ltd. | Diazabicyclooctane derivatives useful as .beta.-lactamase inhibitor and process for preparing the same |
-
2015
- 2015-03-12 US US15/129,971 patent/US9688677B1/en not_active Expired - Fee Related
- 2015-03-12 JP JP2016559202A patent/JP2017508775A/ja active Pending
- 2015-03-12 MX MX2016012648A patent/MX2016012648A/es unknown
- 2015-03-12 KR KR1020167030163A patent/KR20160138538A/ko not_active Withdrawn
- 2015-03-12 IN IN1192MU2014 patent/IN2014MU01192A/en unknown
- 2015-03-12 BR BR112016022437A patent/BR112016022437A2/pt not_active Application Discontinuation
- 2015-03-12 EP EP15717230.5A patent/EP3126363A1/en not_active Withdrawn
- 2015-03-12 WO PCT/IB2015/051797 patent/WO2015150941A1/en not_active Ceased
- 2015-03-12 CN CN201580016887.6A patent/CN107074858A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103328476A (zh) * | 2010-12-22 | 2013-09-25 | 明治制果药业株式会社 | 光学活性二氮杂环辛烷衍生物及其制备方法 |
| WO2013038330A1 (en) * | 2011-09-13 | 2013-03-21 | Wockhardt Limited | Nitrogen containing compounds and their use |
| CA2874279A1 (en) * | 2012-05-30 | 2013-12-05 | Meiji Seika Pharma Co., Ltd. | Diazabicyclooctane derivatives useful as .beta.-lactamase inhibitor and process for preparing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2016012648A (es) | 2017-01-11 |
| KR20160138538A (ko) | 2016-12-05 |
| US20170174686A1 (en) | 2017-06-22 |
| IN2014MU01192A (enExample) | 2015-10-02 |
| US9688677B1 (en) | 2017-06-27 |
| WO2015150941A1 (en) | 2015-10-08 |
| JP2017508775A (ja) | 2017-03-30 |
| EP3126363A1 (en) | 2017-02-08 |
| BR112016022437A2 (pt) | 2017-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170818 |
|
| WD01 | Invention patent application deemed withdrawn after publication |