CN107064083A - A kind of fluorescence observation device of the adjustable visual field of full angle - Google Patents
A kind of fluorescence observation device of the adjustable visual field of full angle Download PDFInfo
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- CN107064083A CN107064083A CN201710076183.9A CN201710076183A CN107064083A CN 107064083 A CN107064083 A CN 107064083A CN 201710076183 A CN201710076183 A CN 201710076183A CN 107064083 A CN107064083 A CN 107064083A
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- Prior art keywords
- fluorescence
- visual field
- observation device
- full angle
- measurement head
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/02—Viewing or reading apparatus
- G02B27/022—Viewing apparatus
- G02B27/024—Viewing apparatus comprising a light source, e.g. for viewing photographic slides, X-ray transparancies
Abstract
The invention discloses a kind of fluorescence observation device of the adjustable visual field of full angle, including：Measurement head, the light hole being placed under measurement head, the excitation source being placed on light hole, excitation source irradiates and inspires the object to be observed of fluorescence in reception, the reflected excitation light for receiving and filtering out fluorescence is placed in high-pass filtering piece between measurement head and object to be observed, is obliquely installed in the speculum of high-pass filtering piece upper end, receives the plus lens that reflection changes the fluorescence behind direction, receive the CCD camera of the fluorescence after convergence, the achromatic lens head assembly between speculum and plus lens.The present invention provides a kind of fluorescence observation device of the adjustable visual field of full angle, measurement head of the invention can 360 ° of full angles rotate around optical axis, the no dead angle of observation, while ensureing that whole light path imaging effect is consistent；And reduce distortion and aberration, improve the definition of CCD camera imaging.
Description
Technical field
The present invention relates to dentistry field, more particularly to a kind of fluorescence observation device.
Background technology
Currently, with the progress and the improvement of people's living standards of medical science, medical model from it is former using disease treatment as
Zero turn radius is centered on early stage health prevention, and people come to realise the serious harm of carious disease in recent years, carious tooth just by
Step obtains the extensive concern of society, and the prevention how to do sth. in advance and the generation of diagnosis carious tooth are referred to as new study hotspot.Non- light
Learning carious tooth detection method has subjective experience or damaging property, therefore with significant limitation, is examined using optical means
Disconnected carious tooth, has the advantages that lossless, visualization, quantification.
Its main comprise material hydroxyapatite of dental tissue and collagen etc., under it is purple light excited in purple light and closely,
The fluorescence of visible region wave band can be produced.Carious tooth detection technique based on fluorescence is namely based on the glimmering of healthy tooth and disease damage tooth
The otherness of light spectrum, so as to detect that dental caries damage degree.
The Buccodental detection means of in the market, is generally positioned over front end by CCD chip, and thickness can not be controlled, is unfavorable for
The miniaturization of detection device, and probe integration is fixed, it is impossible to change observed direction, visual field size can not be adjusted；The present invention
The problem of solving such.
The content of the invention
To solve the deficiencies in the prior art, it is an object of the invention to provide a kind of fluorescence observation of the adjustable visual field of full angle
Device, measurement head of the invention can 360 ° of full angles rotated around optical axis, no dead angle is observed, while ensureing whole light path imaging
Effect is consistent；And reduce distortion and aberration, improve the definition of CCD camera imaging；The fluorescence observation apparatus structure of the present invention is tight
Gather, simply, it is ensured that processing characteristics, reduce the size and probe microstructure size of optical system, advantageously reduce fluorescence sight
The requirement of survey condition, improves the areas imaging of fluorescence observation, can be used under the scene of narrow space.
In order to realize above-mentioned target, the present invention is adopted the following technical scheme that：
A kind of fluorescence observation device of the adjustable visual field of full angle, including：Measurement head, the light hole being placed under measurement head is placed in logical
Excitation source irradiates and inspires the object to be observed of fluorescence in excitation source on unthreaded hole, reception, receives and filters out fluorescence
Reflected excitation light be placed in high-pass filtering piece between measurement head and object to be observed, be obliquely installed in high-pass filtering piece upper end
Speculum, receive reflection change direction after fluorescence plus lens, receive convergence after fluorescence CCD camera, located at anti-
The achromatic lens head assembly penetrated between mirror and plus lens.
A kind of fluorescence observation device of the foregoing adjustable visual field of full angle, including：Excitation source is around light hole annular
The LED/light source of placement.
A kind of fluorescence observation device of the foregoing adjustable visual field of full angle, LED/light source is the paster that 5 wavelength are 405nm
LED.
A kind of fluorescence observation device of the foregoing adjustable visual field of full angle, in addition to：It is connected to measurement head and fixation reflex
The rotating device of mirror.
A kind of fluorescence observation device of the foregoing adjustable visual field of full angle, rotating device is 360 ° of rotating devices.
A kind of fluorescence observation device of the foregoing adjustable visual field of full angle, achromatic lens head assembly is that two achromatisms are saturating
Mirror.
The present invention is advantageous in that：The present invention provides a kind of fluorescence observation device of the adjustable visual field of full angle, this hair
Bright fluorescence is beaten to be turned on the mirror, after being combined through achromat, and concentrated lens enter CCD camera, is ensureing to regard greatly
In the case of, distortion and the aberration of imaging are reduced, the definition of imaging is improved；The present invention is measured by mechanical rotational structure
Head can rotate in horizontal and vertical face, it is ensured that 360 ° of full angles observe no dead angle；By adjusting mechanical rotational structure, energy
Enough change visual field size, while ensureing that whole light path imaging effect is consistent；Fluorescence observation apparatus structure of the invention is compact, letter
It is single, it is ensured that processing characteristics, the size and probe microstructure size of optical system are reduced, fluorescence observation condition is advantageously reduced
Requirement, improve the areas imaging of fluorescence observation, can be used under the scene of narrow space.
Brief description of the drawings
Fig. 1 is a kind of structural representation of embodiment of the present invention；
The implication of reference in figure：
1 object to be observed, 2 high-pass filters, 3 light holes, 4 LED/light sources, 5 speculums, 6 rotating devices, 7 achromatisms
Camera lens, 8 achromats, 9 CCD cameras.
Embodiment
Make specific introduce to the present invention below in conjunction with the drawings and specific embodiments.
A kind of fluorescence observation device of the adjustable visual field of full angle, including：Measurement head, the light hole 3 being placed under measurement head, puts
Excitation source irradiates and inspires the object to be observed 1 of fluorescence in excitation source on light hole 3, reception, receives and filters
The reflected excitation light for falling fluorescence is placed in high-pass filtering piece between measurement head and object to be observed 1, is obliquely installed in high pass filter
The speculum 5 of wave plate upper end, receives the plus lens that reflection changes the fluorescence behind direction, receives the CCD phases of the fluorescence after convergence
Machine 9, the component of achromat 7 between speculum 5 and plus lens.
In order to avoid uneven irradiation and local irradiation, fluorescence observation device, including：Excitation source is around above-mentioned thang-kng
The LED/light source 4 that the annular of hole 3 is placed；As a preferred embodiment, LED/light source 4 is the paster LED lamp that 5 wavelength are 405nm.It is such
Design makes the light being irradiated on object 1 to be observed uniform.Object under test, which is illuminated, inspires fluorescence, and reflected excitation light is through high pass
Optical filter 2 is filtered out, and enters the fluorescence only inspired of measurement head.
Fluorescence observation device, in addition to：It is connected to the rotating device of above-mentioned measurement head and stationary mirror 5.Rotating dress
It is set to 360 degree of rotating devices.The present apparatus is reflected into optical signal in aftertreatment device by speculum 55, in rotating device 6
During rotation, speculum 55 is rotated with, and changes the angle for receiving optical signal.Because rotating device 6 can be any with 360 °
Rotation, speculum 55 can also receive optical signal with any angle.
As a preferred embodiment, the component of achromat 7 is two achromatic lens.Can be more using two achromatic lens
Good color difference eliminating, and two lens have different refractive index and Abbe number.
During work, 5 paster 405nm wavelength LED are placed as excitation source in measurement head lower end around the annular of light hole 3,
Tooth sample surface excitation goes out fluorescence, and fluorescence extracts visible ray long-wave band fluorescence signal by high-pass filter 2.Measurement head with
Horizon bar is connected by mechanical rotational structure, by mechanical rotational structure, and measurement head can rotate in horizontal and vertical face, really
Protect 360 ° of full angles and observe no dead angle, by adjusting mechanical rotational structure, visual field size can be changed, while ensureing whole light
Road imaging effect is consistent；Fluorescence is beaten to be turned on speculum 5, after the component color difference eliminating of achromat 7, most saturating through convergence afterwards
Mirror enters CCD camera 9, in the case where ensureing big visual field, reduces distortion and the aberration of imaging, improves the definition of imaging.
The present invention provides a kind of fluorescence observation device of the adjustable visual field of full angle, and fluorescence of the invention is beaten on speculum 5
Turn to, after being combined through achromat 7, concentrated lens enter CCD camera 9, in the case where ensureing big visual field, reduce into
The distortion of picture and aberration, improve the definition of imaging；The present invention can be horizontal and vertical by mechanical rotational structure measurement head
Rotated in face, it is ensured that 360 ° of full angles observe no dead angle；By adjusting mechanical rotational structure, visual field size can be changed, together
When ensure that whole light path imaging effect is consistent；The fluorescence observation apparatus structure of the present invention is compact, simple, it is ensured that processing characteristics,
The size and probe microstructure size of optical system are reduced, the requirement of fluorescence observation condition is advantageously reduced, improves fluorescence
The areas imaging of observation, can be used under the scene of narrow space.
The basic principles, principal features and advantages of the present invention have been shown and described above.The technical staff of the industry should
Understand, the invention is not limited in any way for above-described embodiment, it is all to be obtained by the way of equivalent substitution or equivalent transformation
Technical scheme, all falls within protection scope of the present invention.
Claims (6)
1. a kind of fluorescence observation device of the adjustable visual field of full angle, it is characterised in that including：Measurement head, is placed in above-mentioned measurement head
Under light hole, the excitation source being placed on above-mentioned light hole, excitation source irradiates and inspires the to be observed of fluorescence in reception
Object, the reflected excitation light for receiving and filtering out fluorescence is placed in high-pass filtering between above-mentioned measurement head and object to be observed
Piece, is obliquely installed in the speculum of above-mentioned high-pass filtering piece upper end, receives the plus lens that reflection changes the fluorescence behind direction, connects
The CCD camera for the fluorescence collected after gathering, the achromatic lens head assembly between above-mentioned speculum and plus lens.
2. a kind of fluorescence observation device of the adjustable visual field of full angle according to claim 1, it is characterised in that including：On
It is the LED/light source placed around above-mentioned light hole annular to state excitation source.
3. a kind of fluorescence observation device of the adjustable visual field of full angle according to claim 2, it is characterised in that above-mentioned LED
Light source is the paster LED lamp that 5 wavelength are 405nm.
4. the fluorescence observation device of the adjustable visual field of a kind of full angle according to claim 1, it is characterised in that also include：
It is connected to the rotating device of above-mentioned measurement head and stationary mirror.
5. a kind of fluorescence observation device of the adjustable visual field of full angle according to claim 4, it is characterised in that above-mentioned rotation
360 ° of rotating devices of device.
6. a kind of fluorescence observation device of the adjustable visual field of full angle according to claim 4, it is characterised in that above-mentioned colour killing
Poor lens assembly is two achromatic lens.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710076183.9A CN107064083A (en) | 2017-02-13 | 2017-02-13 | A kind of fluorescence observation device of the adjustable visual field of full angle |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710076183.9A CN107064083A (en) | 2017-02-13 | 2017-02-13 | A kind of fluorescence observation device of the adjustable visual field of full angle |
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| CN107064083A true CN107064083A (en) | 2017-08-18 |
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| CN201710076183.9A Pending CN107064083A (en) | 2017-02-13 | 2017-02-13 | A kind of fluorescence observation device of the adjustable visual field of full angle |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108143396A (en) * | 2018-01-19 | 2018-06-12 | 苏州江奥光电科技有限公司 | A kind of portable early stage caries diagnostic device and diagnostic method based on fluorescence imaging |
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| CN102178512A (en) * | 2011-04-12 | 2011-09-14 | 北京航空航天大学 | Double-parameter fluorescence molecular tomography device and method for multi-optical information synchronous detection |
| CN102488564A (en) * | 2011-12-15 | 2012-06-13 | 杭州电子科技大学 | Dental plaque detector capable of imaging by aid of fluorescent area arrays |
| CN103720459A (en) * | 2013-12-27 | 2014-04-16 | 北京航空航天大学 | Fluorescent molecular tomography device and method based on single slip ring and wireless control exciting light scanning |
| CN104939858A (en) * | 2015-04-29 | 2015-09-30 | 北京航空航天大学 | X-ray and fluorescence combined multi-model tomography system and X-ray and fluorescence combined multi-model tomography method |
| CN105092544A (en) * | 2014-05-12 | 2015-11-25 | 绍兴安尼特微电子科技有限公司 | Optical excitation and detection system of fluorescent quantitative PCR detector |
| CN204945041U (en) * | 2015-07-28 | 2016-01-06 | 上海睿钰生物科技有限公司 | The synchronous microscopic imaging device of a kind of many fluorescence channels |
| CN105628664A (en) * | 2016-01-12 | 2016-06-01 | 上海理工大学 | Fluorescent alga in-situ analysis device based on beam splitting and combining of broadband spectrum |
| CN206497042U (en) * | 2017-02-13 | 2017-09-15 | 苏州江奥光电科技有限公司 | A kind of fluorescence observation device of the adjustable visual field of full angle |
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2017
- 2017-02-13 CN CN201710076183.9A patent/CN107064083A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178512A (en) * | 2011-04-12 | 2011-09-14 | 北京航空航天大学 | Double-parameter fluorescence molecular tomography device and method for multi-optical information synchronous detection |
| CN102488564A (en) * | 2011-12-15 | 2012-06-13 | 杭州电子科技大学 | Dental plaque detector capable of imaging by aid of fluorescent area arrays |
| CN103720459A (en) * | 2013-12-27 | 2014-04-16 | 北京航空航天大学 | Fluorescent molecular tomography device and method based on single slip ring and wireless control exciting light scanning |
| CN105092544A (en) * | 2014-05-12 | 2015-11-25 | 绍兴安尼特微电子科技有限公司 | Optical excitation and detection system of fluorescent quantitative PCR detector |
| CN104939858A (en) * | 2015-04-29 | 2015-09-30 | 北京航空航天大学 | X-ray and fluorescence combined multi-model tomography system and X-ray and fluorescence combined multi-model tomography method |
| CN204945041U (en) * | 2015-07-28 | 2016-01-06 | 上海睿钰生物科技有限公司 | The synchronous microscopic imaging device of a kind of many fluorescence channels |
| CN105628664A (en) * | 2016-01-12 | 2016-06-01 | 上海理工大学 | Fluorescent alga in-situ analysis device based on beam splitting and combining of broadband spectrum |
| CN206497042U (en) * | 2017-02-13 | 2017-09-15 | 苏州江奥光电科技有限公司 | A kind of fluorescence observation device of the adjustable visual field of full angle |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108143396A (en) * | 2018-01-19 | 2018-06-12 | 苏州江奥光电科技有限公司 | A kind of portable early stage caries diagnostic device and diagnostic method based on fluorescence imaging |
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