CN107050290A - It is a kind of to be used to improve Chinese medicine composition of insomnia and preparation method thereof - Google Patents

It is a kind of to be used to improve Chinese medicine composition of insomnia and preparation method thereof Download PDF

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Publication number
CN107050290A
CN107050290A CN201710449939.XA CN201710449939A CN107050290A CN 107050290 A CN107050290 A CN 107050290A CN 201710449939 A CN201710449939 A CN 201710449939A CN 107050290 A CN107050290 A CN 107050290A
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parts
chinese medicine
jujube
insomnia
tuber
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陆凤琪
周海嫔
陈文成
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Anhui Muchuntang Natural Medicine Research Development Co Ltd
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Anhui Muchuntang Natural Medicine Research Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The present invention relates to a kind of Chinese medicine composition for being used to improve insomnia and preparation method thereof.It is formulated composition and is expressed as by weight:50~60 parts of astragalus root, 40~60 parts of arillus longan, 80~100 parts of spina date seed, 60~80 parts of Ganoderma Sinense, 60~80 parts of the tuber of dwarf lilyturf, 10~20 parts of donkey-hide gelatin, 200~220 parts of jujube, 120~140 parts of rock sugar.The present invention has a better role to the symptom such as having a sleepless night under sub-health state, forgetful, palpitaition, headache.

Description

It is a kind of to be used to improve Chinese medicine composition of insomnia and preparation method thereof
(1) technical field
The present invention relates to technical field of health care food, and in particular to it is a kind of be used for improve insomnia Chinese medicine composition and Its preparation method.
(2) background technology
Nowadays the pressure of live and work so that many people are perplexed by insomnia, seriously endanger the physical and mental health of people. Insomnia refers to that patient is unsatisfactory on the length of one's sleep and quality and influences a kind of subjective experience of social function in the daytime.Mainly by ring The deficiency of length of one's sleep depth and not caused by the inducements such as border change, direct stimulation, the low, emotion influence of autoimmunity Can dispelling fatigue, regain one's strength and energy, the lighter's difficulty falling asleep, or sleep but not soundly, sometimes sleeping and sometimes waking, or can not sleep again after waking up, weight Then it is insomnia all night, is one of common clinical disease, though being not belonging to endanger disease, hinders people's normal life, work, study And health, and can aggravate or induce palpitaition, the obstruction of qi in the chest, dizziness, the illness such as headache.Obstinate insomnia, brings long-term to patient Pain, or even the dependence to sleeping medicine is formed, and the sleeping medicine of long-term taking can cause iatrogenic disease.
The traditional Chinese medical science thinks that the key point of insomnia and dreamful sleep is caused by negative and positive are become estranged.《The big puzzled opinion of Ling Shu Miraculous Pivot or Divine Axis》Institute's cloud:" defending gas must not Enter the moon, often stay in sun.Stay expires in positive then yang-energy, and completely then sun lifts up Sheng to yang-energy;It must not enter the cloudy then cloudy deficiency of vital energy, therefore insomnia.” 《The evil objective piece of Ling Shu Miraculous Pivot or Divine Axis》Point out:" modern pathogens intruding into ZANG FU-organs is then defended gas and walked alone in outer, goes in sun, must not enter the moon.Row in Positive then yang-energy is contained, and yang-energy Sheng Zeyang lifts up sunken, must not enter the moon, the deficiency of Yin, therefore do not close the eyes." visible, it is the pass of insomnia and dreamful sleep that negative and positive, which are become estranged, Where key.《The blue secret allusion quotation opinion of Plain Questions spirit》Say:" heart person, the viscus likened to the monarch in the body, gods go out here.”《Plain Questions declares five gas》Cloud: " heart storing spirit ", highlights the heart and the relation of god.《Jing Yue's complete work is insomnia》Say:" lid is slept, and this is cloudy, and its master of god, Shen Anze sleeps, Refreshing uneasiness is then insomnia." mind imbalance, mind is uneasy, and sun then causes insomnia not as the moon.
At present for the treatment of insomnia, many using Drug treatment, Western medicine such as stabilizes hypnotic sedative agent, clinical effectiveness It is good, but long-term use can form dependence, cause failure of memory, Respiratory Disturbances, parahypnosis, personality Feeling changes Deng there is excitant to stomach, during by liver, renal metabolism, the burden of liver kidney can be increased, cause damage.Chinese medicine is more with medicine Material prototype carrys out preparation, and utilization rate of active components is low, and effect is not notable, and mouthfeel is bad, in-convenience in use.The present invention is to utilize medicine The homologous Chinese medicine of food can improve the health food of sleep quality to be made.
(3) content of the invention
Can be with nourishing qi and blood, mental-tranquilization it is an object of the invention to provide one kind, the Chinese traditional medicine composition with improvement sleep Thing.
To achieve the above object, the technical solution adopted by the present invention is as follows:
A kind of to be used to improve Chinese medicine composition of insomnia and preparation method thereof, formula composition is represented by weight For:
50~60 parts of astragalus root, 40~60 parts of arillus longan, 80~100 parts of spina date seed, 60~80 parts of Ganoderma Sinense, the tuber of dwarf lilyturf 60~ 80 parts, 10~20 parts of donkey-hide gelatin, 200~220 parts of jujube, 120~140 parts of rock sugar.
Advantage of the invention is that having preferably to the symptom such as having a sleepless night under sub-health state, forgetful, palpitaition, headache Improvement result.Based on arillus longan, spina date seed and jujube of the selection with integration of drinking and medicinal herbs, then it is aided with astragalus root, Ganoderma Sinense, donkey-hide gelatin And the tuber of dwarf lilyturf.Spina date seed nourishing the liver is enriched blood in prescription of the present invention, antitoxic heart-soothing and sedative;Tuber of dwarf lilyturf nourishing Yin and moistening dryness, clearing away the heart fire and tranquillizing;Ganoderma Sinense tonifying Qi is pacified God;Astragalus root, arillus longan, jujube, donkey-hide gelatin, rock sugar blood-enrich, mental-tranquilization.To full of beard labor excessively, caused by qi-blood deficiency Insomnia, palpitaition, neurasthenia, headache and other effects are substantially.
(4) embodiment:
Technical scheme is further described below in conjunction with embodiment, but claimed scope not office It is limited to described.
Embodiment 1:Weigh 60 parts of astragalus root, 60 parts of arillus longan, 100 parts of spina date seed, 80 parts of Ganoderma Sinense, 80 parts of the tuber of dwarf lilyturf, Ah 20 parts of glue, 200 parts of jujube, 120 parts of rock sugar.By spina date seed with being stir-fried by a small fire, be ground into coarse powder, then with astragalus root, arillus longan, In Ganoderma Sinense, the tuber of dwarf lilyturf, jujube mixing, input Chinese medicine extracting tank, soak to medicinal material and 100 DEG C of extractions are heated to after being impregnated with completely Three times, merge decoction and be concentrated into the volume of 1.5 times of weight of material, 12000r/min is centrifuged online, supernatant spray drying is standby With;Donkey-hide gelatin and rock sugar are crushed, crossed after 100 mesh sieves, after being well mixed with extract powder, plus particle is made in dextrin, drying is whole After grain, ultraviolet disinfection, packaging is produced.
Embodiment 2:Weigh 50 parts of astragalus root, 50 parts of arillus longan, 100 parts of spina date seed, 60 parts of Ganoderma Sinense, 80 parts of the tuber of dwarf lilyturf, Ah 15 parts of glue, 200 parts of jujube, 120 parts of rock sugar.By astragalus root, arillus longan, Ganoderma Sinense and the taste Chinese medicine of the tuber of dwarf lilyturf 4, Chinese medicine extracting tank is put into In, soak to medicinal material and 100 DEG C are heated to after being impregnated with completely extract three times, merge decoction and be simultaneously concentrated into 1.5 times of weight of material Volume, 12000r/min centrifuges online, supernatant spray drying, standby;By spina date seed with being stir-fried by a small fire, crush, cross 100 mesh It is standby after sieve;By jujube cleaning, drying, stoning is standby;After donkey-hide gelatin and rock sugar co-grinding, sticky wire drawing shape is heated to, Then said extracted thing powder, spiny jujuba seed powder are added, after stirring, by compacting, refrigeration, segment is added in jujube, sterilizing, Packaging, is produced.
Clinical verification effect:Liu, female, 28 years old, overtime work of staying up late for a long time, irregular eating, in the recent period often sense palpitaition, shortness of breath, Lassitude and weak, insomnia and dreamful sleep, headache.The medicine jujube of the embodiment of the present invention 2 is taken, on daily daytime 3, first 1 is slept, 5 days, disease is used in conjunction Shape substantially mitigates.Later stage adjusts the daily schedule, and reasonable diet does not occur above-mentioned illness so far.

Claims (5)

1. a kind of be used to improve Chinese medicine composition of insomnia and preparation method thereof, it is characterised in that:By following portions by weight Chinese medicine be made:
50~60 parts of astragalus root, 40~60 parts of arillus longan, 80~100 parts of spina date seed, 60~80 parts of Ganoderma Sinense, the tuber of dwarf lilyturf 60~80 Part, 10~20 parts of donkey-hide gelatin, 200~220 parts of jujube, 120~140 parts of rock sugar.
2. according to claim 1 a kind of for improving Chinese medicine composition of insomnia and preparation method thereof, its feature It is:The parts by weight of the Chinese medicine are:
50 parts of astragalus root, 50 parts of arillus longan, 100 parts of spina date seed, 60 parts of Ganoderma Sinense, 80 parts of the tuber of dwarf lilyturf, 15 parts of donkey-hide gelatin, 200 parts of jujube, 120 parts of rock sugar.
3. according to any described a kind of Chinese medicine composition for being used to improve insomnia of claim 1~2 and preparation method thereof, It is characterized in that:Astragalus root, arillus longan, spina date seed, Ganoderma Sinense, the tuber of dwarf lilyturf, donkey-hide gelatin, jujube, rock sugar are weighed by weight.By acid Jujube kernel is ground into coarse powder with being stir-fried by a small fire, and is then mixed with astragalus root, arillus longan, Ganoderma Sinense, the tuber of dwarf lilyturf, jujube, and input Chinese medicine is carried Take in tank, soak to medicinal material and 100 DEG C are heated to after being impregnated with completely extract three times, merge decoction and be simultaneously concentrated into weight of material 1.5 times of volume, 12000r/min is centrifuged online, supernatant spray drying, standby;Donkey-hide gelatin and rock sugar are crushed, 100 mesh sieves are crossed Afterwards, after being well mixed with extract powder, plus particle is made in dextrin, drying, whole grain, after ultraviolet disinfection, and packaging is produced.
4. according to any described a kind of Chinese medicine composition for being used to improve insomnia of claim 1~2 and preparation method thereof, It is characterized in that:Astragalus root, arillus longan, spina date seed, Ganoderma Sinense, the tuber of dwarf lilyturf, donkey-hide gelatin, jujube, rock sugar are weighed by weight.It will process In the Radix Astragali, arillus longan, Ganoderma Sinense and the taste Chinese medicine of the tuber of dwarf lilyturf 4, input Chinese medicine extracting tank, soak to medicinal material and heated after being impregnated with completely Extracted three times to 100 DEG C, merge decoction and be concentrated into the volume of 1.5 times of weight of material, 12000r/min is centrifuged online, supernatant Spray drying, it is standby;By spina date seed with being stir-fried by a small fire, crush, cross after 100 mesh sieves, it is standby;By jujube cleaning, drying, it is enucleated, It is standby;After donkey-hide gelatin and rock sugar co-grinding, sticky wire drawing shape is heated to, said extracted thing powder, spiny jujuba seed powder is then added, stirs After mixing uniformly, by compacting, refrigeration, segment is added in jujube, is sterilized, and is packed, is produced.
5. according to any described a kind of Chinese medicine composition for being used to improve insomnia of claims 1 to 3 and preparation method thereof, It is characterized in that oral liquid can be prepared into.
CN201710449939.XA 2017-06-15 2017-06-15 It is a kind of to be used to improve Chinese medicine composition of insomnia and preparation method thereof Pending CN107050290A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114190505A (en) * 2021-12-15 2022-03-18 哈尔滨健领医疗科技有限公司 Sleep-aiding solid beverage and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732439A (en) * 2008-11-05 2010-06-16 牛建勋 Chinese medicinal preparation for treating insomnia
CN102366004A (en) * 2011-06-22 2012-03-07 王学文 Tea for calming nerves, nourishing heart and preserving health
CN104435652A (en) * 2014-11-19 2015-03-25 唐加宜 Ointment for treating insomnia and preparation method thereof
CN105267637A (en) * 2015-11-19 2016-01-27 哈尔滨圣吉药业股份有限公司 Fatigue eliminating dispersible tablet and method for preparing same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101732439A (en) * 2008-11-05 2010-06-16 牛建勋 Chinese medicinal preparation for treating insomnia
CN102366004A (en) * 2011-06-22 2012-03-07 王学文 Tea for calming nerves, nourishing heart and preserving health
CN104435652A (en) * 2014-11-19 2015-03-25 唐加宜 Ointment for treating insomnia and preparation method thereof
CN105267637A (en) * 2015-11-19 2016-01-27 哈尔滨圣吉药业股份有限公司 Fatigue eliminating dispersible tablet and method for preparing same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114190505A (en) * 2021-12-15 2022-03-18 哈尔滨健领医疗科技有限公司 Sleep-aiding solid beverage and preparation method thereof

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Application publication date: 20170818