CN107049982A - A kind of ion VC pills and preparation method thereof - Google Patents
A kind of ion VC pills and preparation method thereof Download PDFInfo
- Publication number
- CN107049982A CN107049982A CN201710402317.1A CN201710402317A CN107049982A CN 107049982 A CN107049982 A CN 107049982A CN 201710402317 A CN201710402317 A CN 201710402317A CN 107049982 A CN107049982 A CN 107049982A
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- Prior art keywords
- parts
- ion
- pills
- sodium
- potassium chloride
- Prior art date
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- 239000006187 pill Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 44
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 29
- 150000002500 ions Chemical class 0.000 claims abstract description 29
- 239000011734 sodium Substances 0.000 claims abstract description 29
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 29
- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000011782 vitamin Substances 0.000 claims abstract description 25
- 239000001103 potassium chloride Substances 0.000 claims abstract description 22
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 22
- 239000000945 filler Substances 0.000 claims abstract description 17
- 239000011230 binding agent Substances 0.000 claims abstract description 16
- 239000000049 pigment Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 239000000314 lubricant Substances 0.000 claims abstract description 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 10
- 229930195725 Mannitol Natural products 0.000 claims description 10
- 229930006000 Sucrose Natural products 0.000 claims description 10
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 10
- 239000000594 mannitol Substances 0.000 claims description 10
- 235000010355 mannitol Nutrition 0.000 claims description 10
- 239000005720 sucrose Substances 0.000 claims description 10
- 229920002472 Starch Polymers 0.000 claims description 9
- 239000008107 starch Substances 0.000 claims description 9
- 235000019698 starch Nutrition 0.000 claims description 9
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 7
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 7
- 239000001630 malic acid Substances 0.000 claims description 7
- 235000011090 malic acid Nutrition 0.000 claims description 7
- 235000021433 fructose syrup Nutrition 0.000 claims description 6
- -1 isomaltoketose Chemical compound 0.000 claims description 6
- 238000005453 pelletization Methods 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000011122 softwood Substances 0.000 claims description 6
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 4
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 4
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 4
- 229960004106 citric acid Drugs 0.000 claims description 4
- 235000015165 citric acid Nutrition 0.000 claims description 4
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- 239000000832 lactitol Substances 0.000 claims description 4
- 235000010448 lactitol Nutrition 0.000 claims description 4
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims description 4
- 229960003451 lactitol Drugs 0.000 claims description 4
- 239000008101 lactose Substances 0.000 claims description 4
- 229940099690 malic acid Drugs 0.000 claims description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 4
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 4
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 4
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 4
- 229940013618 stevioside Drugs 0.000 claims description 4
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 4
- 235000019202 steviosides Nutrition 0.000 claims description 4
- 239000006188 syrup Substances 0.000 claims description 4
- 235000020357 syrup Nutrition 0.000 claims description 4
- 239000000811 xylitol Substances 0.000 claims description 4
- 235000010447 xylitol Nutrition 0.000 claims description 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 4
- 229960002675 xylitol Drugs 0.000 claims description 4
- 108010011485 Aspartame Proteins 0.000 claims description 2
- 239000000605 aspartame Substances 0.000 claims description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 2
- 235000010357 aspartame Nutrition 0.000 claims description 2
- 229960003438 aspartame Drugs 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 240000000111 Saccharum officinarum Species 0.000 claims 1
- 235000007201 Saccharum officinarum Nutrition 0.000 claims 1
- 235000009508 confectionery Nutrition 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract description 16
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract description 8
- 229930003268 Vitamin C Natural products 0.000 abstract description 8
- 235000019154 vitamin C Nutrition 0.000 abstract description 8
- 239000011718 vitamin C Substances 0.000 abstract description 8
- 206010067484 Adverse reaction Diseases 0.000 abstract description 4
- 230000006838 adverse reaction Effects 0.000 abstract description 4
- 230000006872 improvement Effects 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 229920000881 Modified starch Polymers 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 229960001855 mannitol Drugs 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229910001415 sodium ion Inorganic materials 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000007976 Ketosis Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000005660 chlorination reaction Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000000890 drug combination Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of ion VC pills and preparation method thereof, it is characterised in that is made up of the raw material of following weight proportion:0.5 5 parts of vitamine C sodium, 1 10 parts of potassium chloride, 0 100 parts of binder, 0 100 parts of filler, 05 parts of lubricant, 0 20 parts of flavouring, 01 parts of pigment;The invention has the advantages that:Fill up the blank of domestic ion VC pills, there is provided it is a kind of safely, effectively, quick-acting, steady quality ion VC pills and preparation method thereof, expand the scope of application of vitamine C sodium, solve the use limitation that vitamin C is orally brought, can also reduce it and bring more adverse reaction.
Description
Technical field
The invention belongs to food, health food, medicine field, it is related to a kind of composite preparation and preparation method thereof, especially
It is to be related to a kind of ion VC pills and preparation method thereof.
Background technology
Discoloration is decomposed because vitamin C is especially oxidizable, the quality problems such as quality is unstable, mass fraction declines occurs,
So as to influence product quality and drug safety;Because vitamin C has highly acid, this brings certain potential safety hazard and more to product
Adverse reaction.
Vitamine C sodium(That is L-AA sodium)Effect it is identical with vitamin C, but due to being sodium salt, so performance is more
It is stable, while there is no ascorbic highly acid, can simultaneously be taken with multi-medicament, better than vitamin C;Vitamine C sodium
Exist after into human body with ion vc state, it is easier to be absorbed by the body, participate in internal a variety of metabolic processes of human body.
The vitamine C sodium pill that the present invention is developed can overcome vitamin C strong acid close to neutrality in clinical heavy dose of medication
Property brings adverse reaction and drug combination limitation;Meanwhile, also vitamin C can be higher than due to vitamine C sodium stability, improved
Drug quality;Take in excessive sodium ion and easily cause hypertension, potassium chloride is with the addition of in the present invention, for balancing vitamine C sodium
In sodium ion so that pill of the invention takes safer, and the scope of application is wider.
The content of the invention
For background technology problem encountered, it is an object of the invention to provide it is a kind of safely, effectively, quick-acting, quality
Stable ion VC pills and preparation method thereof.
In order to achieve the above object, the present invention is adopted the following technical scheme that:A kind of ion VC pills, it is characterised in that by
The raw material composition of following weight proportion:
0.5-5 parts of vitamine C sodium, 1-10 parts of potassium chloride, 0-100 parts of binder, 0-100 parts of filler, 0-5 parts of lubricant is rectified
0-20 parts of taste agent, 0-1 parts of pigment.
As an improvement, being made up of the raw material of following weight proportion:5 parts of vitamine C sodium, 1 part of potassium chloride, binder 100
Part, 5 parts of lubricant, 1 part of pigment.
As an improvement, being made up of the raw material of following weight proportion:0.5 part of vitamine C sodium, 10 parts of potassium chloride, filler 100
Part, 20 parts of flavouring.
As an improvement, being made up of the raw material of following weight proportion:3 parts of vitamine C sodium, 5 parts of potassium chloride, 46 parts of binder,
55 parts of filler, 3 parts of lubricant, 9 parts of flavouring, 0.6 part of pigment.
As an improvement, binder is:Fructose syrup, syrup, sucrose, starch, powder-beta-dextrin, one kind of microcrystalline cellulose or several
Kind.
As an improvement, filler is:One or more in lactose, starch, pregelatinized starch, sucrose, mannitol etc..
As an improvement, flavouring is:Essence, fruit powder, mannitol, citric acid, malic acid, stevioside, xylitol, different malt
Ketose, Aspartame, the one or more of lactitol.
Another object of the present invention is to provide a kind of preparation method of ion VC pills, comprised the following steps:By potassium chloride and glutinous
Mixture, filler crushed 100 mesh sieves, added vitamine C sodium, flavouring, lubricant and pigment and were well mixed, softwood processed, pressure
Ball is made, parcel sugar-coat is produced.
Compared with prior art, the invention has the advantages that:Filling up the blank of domestic ion VC pills, there is provided one
Kind safely, effectively, quick-acting, steady quality ion VC pills and preparation method thereof, expand the scope of application of vitamine C sodium, solution
Certainly vitamin C is orally brought
Use limitation, can also reduce it and bring more adverse reaction.
Embodiment
In order to be better understood from the purpose of the present invention, feature and effect etc., with reference to skill of the specific embodiment to the present invention
Art scheme is described further.
Embodiment 1
A kind of ion VC pills, are made up of the raw material of following weight proportion:5 parts of vitamine C sodium, 1 part of potassium chloride, binder 100
Part, 5 parts of lubricant, 1 part of pigment.
Binder is:Fructose syrup, syrup, sucrose, starch, powder-beta-dextrin, the one or more of microcrystalline cellulose.
A kind of preparation method of ion VC pills, comprises the following steps:Potassium chloride and binder were crushed into 100 mesh sieves,
Add vitamine C sodium, lubricant and pigment well mixed, softwood processed suppresses pelletization, and parcel sugar-coat is produced.
Embodiment 2
A kind of ion VC pills, are made up of the raw material of following weight proportion:0.5 part of vitamine C sodium, 10 parts of potassium chloride, filler
100 parts, 20 parts of flavouring.
Filler is:One or more in lactose, starch, pregelatinized starch, sucrose, mannitol etc..
Flavouring is:Essence, fruit powder, mannitol, citric acid, malic acid, stevioside, xylitol, isomaltoketose, A Si
Ba Tian, lactitol one or more.
A kind of preparation method of ion VC pills, comprises the following steps:Potassium chloride and filler were crushed into 100 mesh sieves, added
Vitamine C sodium, flavouring and pigment are well mixed, softwood processed, suppress pelletization, and parcel sugar-coat is produced.
Embodiment 3
A kind of ion VC pills, are made up of the raw material of following weight proportion:3 parts of vitamine C sodium, 5 parts of potassium chloride, binder 46
Part, 55 parts of filler, 3 parts of lubricant, 9 parts of flavouring, 0.6 part of pigment.
Binder is:Fructose syrup, syrup, sucrose, starch, powder-beta-dextrin, the one or more of microcrystalline cellulose.
Filler is:One or more in lactose, starch, pregelatinized starch, sucrose, mannitol etc..
Flavouring is:Essence, fruit powder, mannitol, citric acid, malic acid, stevioside, xylitol, isomaltoketose, A Si
Ba Tian, lactitol one or more.
A kind of preparation method of ion VC pills, comprises the following steps:Potassium chloride and binder, filler were crushed into 100 mesh
Sieve, adds vitamine C sodium, flavouring, lubricant and pigment and is well mixed, softwood processed, suppresses pelletization, and parcel sugar-coat is produced.
Embodiment 4
A kind of ion VC pills, are made up of the raw material of following weight proportion:20 parts of fructose syrup, 0.5 part of vitamine C sodium, chlorination
1 part of potassium, 60 parts of sucrose.
A kind of preparation method of ion VC pills, comprises the following steps:By sucrose, 60 parts are put into sugar dissolving kettle, add water 18 parts
Change sugar, 300 mesh screens, vacuum sugar boiling is concentrated into relative density 1.2-1.3, by sucrose, 20 parts of fructose syrup and vitamine C sodium
0.5 part, 1 part of potassium chloride, are well mixed, softwood processed, suppress pelletization, and parcel sugar-coat is produced.
Embodiment 5
A kind of ion VC pills, are made up of the raw material of following weight proportion:Mannitol 20
Part, 5 parts of malic acid, 0.5 part of vitamine C sodium, 1 part of potassium chloride, 0.01 part of essence, 0.2 part of cream, 2 parts of milk powder, titanium dioxide
0.05 part of silicon.
A kind of preparation method of ion VC pills, comprises the following steps:Mannitol, potassium chloride and malic acid crushed 100
Mesh sieve, by 1 part of 5 parts of malic acid, the potassium chloride and 0.5 part of vitamine C sodium, 0.01 part of essence, 2 parts of milk powder after above-mentioned pulverize and sieve
It is well mixed, then 0.05 part of 20 parts of mannitol and silica are added with the method for equal increments, it is well mixed, the system of adding water is soft
Material, suppresses pelletization, and parcel sugar-coat is produced.
Detailed description above is only the explanation of the preferred embodiments of the invention, non-therefore the limitation present invention the scope of the claims,
So, all equivalence techniques changes with carried out by this creation description are both contained in the scope of the claims of the present invention.
Claims (8)
1. a kind of ion VC pills, it is characterised in that be made up of the raw material of following weight proportion:
0.5-5 parts of vitamine C sodium, 1-10 parts of potassium chloride, 0-100 parts of binder, 0-100 parts of filler, 0-5 parts of lubricant is rectified
0-20 parts of taste agent, 0-1 parts of pigment.
2. a kind of ion VC pills as claimed in claim 1, it is characterised in that be made up of the raw material of following weight proportion:Dimension
Raw 5 parts of element C sodium, 1 part of potassium chloride, 100 parts of binder, 5 parts of lubricant, 1 part of pigment.
3. a kind of ion VC pills as claimed in claim 1, it is characterised in that be made up of the raw material of following weight proportion:Dimension
Raw 0.5 part of element C sodium, 10 parts of potassium chloride, 100 parts of filler, 20 parts of flavouring.
4. a kind of ion VC pills as claimed in claim 1, it is characterised in that be made up of the raw material of following weight proportion:Dimension
Raw 3 parts of element C sodium, 5 parts of potassium chloride, 46 parts of binder, 55 parts of filler, 3 parts of lubricant, 9 parts of flavouring, 0.6 part of pigment.
5. a kind of ion VC pills as described in Claims 1-4, it is characterised in that binder is:Fructose syrup, syrup, sugarcane
Sugar, starch, powder-beta-dextrin, the one or more of microcrystalline cellulose.
6. a kind of ion VC pills as described in Claims 1-4, it is characterised in that filler is:Lactose, starch, pregelatinated
One or more in starch, sucrose, mannitol etc..
7. a kind of ion VC pills as described in Claims 1-4, it is characterised in that flavouring is:Essence, fruit powder, sweet dew
Alcohol, citric acid, malic acid, stevioside, xylitol, isomaltoketose, Aspartame, the one or more of lactitol.
8. the preparation method of a kind of ion VC pills as described in Claims 1-4, it is characterised in that comprise the following steps:Will
Potassium chloride and binder, filler crushed 100 mesh sieves, added vitamine C sodium, flavouring, lubricant and pigment and were well mixed,
Softwood processed, suppresses pelletization, and parcel sugar-coat is produced.
Priority Applications (1)
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CN201710402317.1A CN107049982A (en) | 2017-06-01 | 2017-06-01 | A kind of ion VC pills and preparation method thereof |
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CN201710402317.1A CN107049982A (en) | 2017-06-01 | 2017-06-01 | A kind of ion VC pills and preparation method thereof |
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Family
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107468647A (en) * | 2017-09-14 | 2017-12-15 | 南通荣成医药化工有限公司 | A kind of ion VC oral liquids |
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CN105832763A (en) * | 2016-05-11 | 2016-08-10 | 广西圣保堂健康产业股份有限公司 | Medicine composition containing sodium L-ascorbate and preparing method of medicine composition |
CN106420655A (en) * | 2016-10-24 | 2017-02-22 | 广西圣保堂健康产业股份有限公司 | Effervescent tablet containing vitamin C sodium and preparation method of effervescent tablet |
CN106420643A (en) * | 2016-10-28 | 2017-02-22 | 广西圣保堂健康产业股份有限公司 | Sodium vitamin C containing chewable tablet and preparation method thereof |
-
2017
- 2017-06-01 CN CN201710402317.1A patent/CN107049982A/en active Pending
Patent Citations (4)
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CN102824315A (en) * | 2012-09-25 | 2012-12-19 | 广西金海堂药业有限责任公司 | Preparation method of vitamin C micro-pill |
CN105832763A (en) * | 2016-05-11 | 2016-08-10 | 广西圣保堂健康产业股份有限公司 | Medicine composition containing sodium L-ascorbate and preparing method of medicine composition |
CN106420655A (en) * | 2016-10-24 | 2017-02-22 | 广西圣保堂健康产业股份有限公司 | Effervescent tablet containing vitamin C sodium and preparation method of effervescent tablet |
CN106420643A (en) * | 2016-10-28 | 2017-02-22 | 广西圣保堂健康产业股份有限公司 | Sodium vitamin C containing chewable tablet and preparation method thereof |
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