CN107049587A - Intelligent menstrual cup - Google Patents

Intelligent menstrual cup Download PDF

Info

Publication number
CN107049587A
CN107049587A CN201710336783.4A CN201710336783A CN107049587A CN 107049587 A CN107049587 A CN 107049587A CN 201710336783 A CN201710336783 A CN 201710336783A CN 107049587 A CN107049587 A CN 107049587A
Authority
CN
China
Prior art keywords
cup
chip
intelligent
runner
menstrual cup
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710336783.4A
Other languages
Chinese (zh)
Inventor
郭宝煊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201710336783.4A priority Critical patent/CN107049587A/en
Publication of CN107049587A publication Critical patent/CN107049587A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/44Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
    • A61F5/451Genital or anal receptacles
    • A61F5/455Genital or anal receptacles for collecting urine or discharge from female member
    • A61F5/4553Genital or anal receptacles for collecting urine or discharge from female member placed in the vagina, e.g. for catamenial use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/44Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
    • A61F5/4404Details or parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H19/00Massage for the genitals; Devices for improving sexual intercourse
    • A61H19/40Devices insertable in the genitals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/06Magnetotherapy using magnetic fields produced by permanent magnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0624Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D5/00Electroplating characterised by the process; Pretreatment or after-treatment of workpieces
    • C25D5/02Electroplating of selected surface areas
    • C25D5/022Electroplating of selected surface areas using masking means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K3/00Apparatus or processes for manufacturing printed circuits
    • H05K3/02Apparatus or processes for manufacturing printed circuits in which the conductive material is applied to the surface of the insulating support and is thereafter removed from such areas of the surface which are not intended for current conducting or shielding
    • H05K3/06Apparatus or processes for manufacturing printed circuits in which the conductive material is applied to the surface of the insulating support and is thereafter removed from such areas of the surface which are not intended for current conducting or shielding the conductive material being removed chemically or electrolytically, e.g. by photo-etch process
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K3/00Apparatus or processes for manufacturing printed circuits
    • H05K3/40Forming printed elements for providing electric connections to or between printed circuits
    • H05K3/42Plated through-holes or plated via connections
    • H05K3/423Plated through-holes or plated via connections characterised by electroplating method
    • H05K3/424Plated through-holes or plated via connections characterised by electroplating method by direct electroplating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared
    • A61N2005/066Radiation therapy using light characterised by the wavelength of light used infrared far infrared
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K2203/00Indexing scheme relating to apparatus or processes for manufacturing printed circuits covered by H05K3/00
    • H05K2203/07Treatments involving liquids, e.g. plating, rinsing
    • H05K2203/0703Plating
    • H05K2203/0723Electroplating, e.g. finish plating

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Manufacturing & Machinery (AREA)
  • Vascular Medicine (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pathology (AREA)
  • Nursing (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Food Science & Technology (AREA)
  • Ecology (AREA)
  • Reproductive Health (AREA)

Abstract

The invention belongs to amenities technical field, more particularly to a kind of intelligent menstrual cup, including cup, intellectual monitoring module, and the power module being electrically connected with intellectual monitoring module, the inside of cup has cup chamber, cup has circular open at the top of cup chamber, the bottom of cup is provided with support handle in the offside of circular open, hold in the palm the runner for being provided with and being turned on cup chamber inside handle, valve of the runner provided with control runner conducting, intellectual monitoring module includes that the blood examination chip of menses can be detected, a glass sensor for chamber internal environment can be monitored, the data acquisition module being electrically connected with respectively with blood examination chip and sensor, and the wireless communication module for transmitting gathered data to intelligent terminal.The present invention can effectively monitor the physiological health data of women physiological period, while setting blood examination chip in menstrual cup, can provide menses testing result within several minutes even several seconds;So as to allow women to know the health status of oneself in time, the daily trouble taken a blood sample to hospital is eliminated.

Description

Intelligent menstrual cup
Technical field
The invention belongs to amenities technical field, more particularly to a kind of intelligent menstrual cup.
Background technology
At present, when determining female physiological periodicity arrives nursed using sanitary napkin, and sanitary napkin leads to when in use Chang Douhui has some drawbacks.First, sanitary napkin belongs to exterior-applied article, in use because placement location is incorrect or defends The problem of absorbability of raw towel in itself is poor causes the phenomenon of leakage;Second, women health when walking or participating in some motions The flank of towel and two legs produce friction, user can be allowed not feel well;3rd, because sanitary napkin is exterior-applied article and is to have water suction Property, so women cannot participate in the underwater movements such as swimming when using sanitary napkin;4th, due to sanitary napkin gas permeability Difference, if if menses are stopped for a long time on sanitary napkin, it is easy to breed bacteria, induces various gynecological diseases, influence women is good for Health;5th, existing various sanitary napkins all can only be disposable, need to consume substantial amounts of resource, use cost is high, and is unfavorable for Low-carbon environment-friendly.
In order to solve above-mentioned various problems, the menstrual cup that can be recycled, existing menstrual cup are now occurred in that on the market Shape exactly likes bell, and it includes cup and is connected to the pull handle of bottom, and the bottom of cup is closing, and pull handle is set one Solid handle.In use, first cleaning, sterilizing by menstrual cup, the adaptation position of intravaginal is then placed in, in certain interval of time Afterwards, by pullling the end of pull handle, the cup of menstrual cup is pulled out into human body, then poured out the liquid such as the menses in cup, clearly After wash clean, then it is reentered into vivo.
Although however, menstrual cup has can be recycled, environmental protection, use cost is low, and lateral leakage protection it is good, than using defending Raw towel is more comfortable, it is more healthy the advantages of, but existing menstrual cup is difficult to be easily accepted by a user, use, except being influenceed it by traditional concept Outside, illustrate that existing menstrual cup still there are problems that.
On the one hand, existing menstrual cup can not show the discharge rate of women menses in real time.The menstrual cup of campanula halleri Halleri is put into A closed effect is produced after in vagina, menstruation cup body structure is used for access menses when female menstrual period comes, but is due to Menstrual cup is placed on inside of human body so that women can not know menses discharge number, thus often occur that menses fill the moon Fail the phenomenon in time discharging menses after cup.
On the other hand, existing menstrual cup can not monitor the health condition of women using menses.All kinds of gynaecology are suffered from now The female ratio of disease accounts for 73%, and more or less can all suffer from different degrees of gynaecological imflammation in life;In urban life Women due to the change of operating pressure and living environment, the reproductive system cancers incidence of disease than 20 years before rise by about one time, and be in Rejuvenation trend.The threat of various diseases, serious reduces women's health composite index.Thus medical expert points out early hair Existing, early treatment is the unique channel for preventing malignant disease, and women should at least do a healthy reproduction inspection every year within more than 18 years old.So And, due to being busy with one's work, a variety of causes such as somewhat expensive, daily few women can actively arrive hospital and carry out routine body inspection Look into.Therefore under normal circumstances, it is most of to be all difficult to discover the problem of cause menalgia or gynecological disease.Such as, women Suffer from gonorrhoea or when Chlamydia infects, symptom of all You nothing obvious generally has already passed by when finding Golden hour;But if if these bacterial numbers constantly rise in female reproductive system, it is more likely that cause pelvic cavity Inflammation, so as to further result in the health problems such as female infertility.
Wherein, blood be flowing in heart and endovascular opaque red liquid, main component be blood plasma, haemocyte and Three kinds of blood platelet.Haemocyte is divided into red blood cell and leucocyte again.Contain various nutritional ingredients, such as inorganic salts, oxygen, metabolism in blood Product, hormone, enzyme and antibody etc., nutritious tissue, regulation organ activity and the effect for defending harmful substance.Each organ of human body Physiology and pathological change, often cause the change of blood constituent, therefore are often required to diagnose the illness by blood count after illness.Menstruation It is that about monthly, the menorrhea amount of general women is 30~50ml, normally because property endometrial cycle comes off with bleeding Menses in alkalescence, color is dark red, odorless, sticky without solidifying, menses are in addition to blood constituent, also containing the broken of endometrium Piece, Ovulation prediction and the vaginal epithelial cell that comes off etc..Refer to the color of menstrual blood through color, normal menstrual blood is general in dark red Color, it is shallower to start color, gradually deepens later, last to switch to pale red again and clean.Refer to the character of menstrual blood, positive reason through matter It is not dilute not thick through matter under condition, solidification is difficult, without obvious clot, no special odor.But, the menses of some women with peculiar smell, What is had is very big through blood volume, may suffer from fibroid, metropolypus, endometriosis and dysthyroid;Have Through blood volume very little, it may be possible to caused by dysfunctional uterine bleeding, Stein-Leventhal syndrome, premature ovarian failure etc..In a word, Menstrual blood is exactly the barometer of female reproductive system, objectively reflects very much the health condition of women.
Regrettably, up to the present still without a set of continuous, complete detection system set up for feminine menstrual blood System and examination criteria, generally, female friend due to shy and painful topic, until reproductive system it is ill it is very serious after Go to a hospital to see a doctor, but be now already belonging to treatment stage, not the transition in routine testing and protection stage;And due to hospital Policy issue and administrative region limitation, it is impossible to set up large-scale broad spectrum activity reproductive system pathological data group, and because hospital is Profit based organisations, the continuous long-term menstrual blood of personal implementation that is directed to that will not be gratuitously detects and sets up corresponding management system.
That is, menstrual blood is a fabulous blood testing sample in fact, menstrual blood realization pair can be utilized completely The disease detection work of women.Therefore, it is necessory to research and develop a both safety and comfort, it is easy to use, and menstrual blood pair can be utilized The intelligent menstrual cup that the health status of women is detected and monitored.
The content of the invention
It is an object of the invention to:It is single for existing menstrual cup function, in-convenience in use deficiency, and provide it is a kind of both It is safety and comfort, easy to use, and the intelligent menstrual cup that the health status of women can be detected and monitored using menstrual blood.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of intelligent menstrual cup, including cup, intellectual monitoring module and the power supply mould being electrically connected with intellectual monitoring module Block, the inside of the cup has cup chamber, and cup has circular open at the top of cup chamber, and the bottom of cup is opened in the circle The offside of mouth is provided with holding in the palm provided with the runner with cup chamber conducting inside handle, the support handle, and the runner is provided with the control stream The valve of road conducting, the intellectual monitoring module includes that the blood examination chip of menses can be detected, can monitor glass chamber internal environment Sensor, the data acquisition module being electrically connected with respectively with the blood examination chip and the sensor and by gathered data to The wireless communication module of intelligent terminal transmission.
Wherein, the effect of circular open is the opening of the cervix phase for causing cup and vagina inner process after being put into women body It coincide so that the menses discharged from opening of the cervix can smoothly flow into a glass intracavitary.The effect of support handle is, when menstrual cup is pushed into the moon After in road, support handle keeps being exposed at outside human body, when needing menstrual cup to be taken out from human body, can involve support handle easily Taking-up menstrual cup;Another effect is can be flowed out when menstrual cup is built with menses from the port of support handle, it is not necessary to will Menstrual cup reduces the pollution frequently from loading procedure again is taken out in human body from internal taking-up.In addition, being located at support handle port Valve it is normal when be to be in closure state, the effect of valve is that the menses for preventing glass intracavitary flow out outside, and when needing cup Only needing to firmly tube squeezing valve during menses discharge in chamber and runner makes its deformation to turn on and flow out menses.
Wherein, the blood examination chip is arranged in the cup cavity wall and/or the runner inner wall, and the blood examination chip can Real-time menses inspection is carried out, menses testing result can be provided within several minutes even several seconds.So as to allow user's energy It is enough to know the health status of oneself in time, to carry out timely prevention from suffering from the diseases or treatment, taken out while eliminating hospital The trouble that blood examination is looked into, this highly shortened the interval time between detection and treatment so that user can quickly, it is inexpensive Ground obtains diagnostic data, and the blood examination conventional compared to hospital, and the blood examination chip causes detection more convenient, more efficient.
The sensor can be arranged on a glass bottom of chamber portion, cup cavity outer wall or runner outer wall, can be supervised by the sensor The amount of menses in menstrual cup is surveyed, and reminds user to be discharged in the suitable time by intelligent terminal;Moreover, it is also possible to logical Cross the color for setting the sensor of difference in functionality to recognize menses, pH value, and the physiological data such as bacterial concentration, and by the data of collection Intelligent terminal is sent to by wireless communication module, the physiology shape of user is relatively can be inferred that by carrying out data analysis Condition, will remind user to go examination in hospital to treat in time, full-scope safeguards women's health if it find that physiology has during exception.
Improved as a kind of of intelligent menstrual cup of the invention, the blood examination chip includes carrier substrate, is arranged at the load The conductive substrate of body substrate and the insulation glue-line for being covered in the conductive substrate, the insulation glue-line offer probe through hole, The probe through hole is provided with the nano metal probe for protruding from insulation film surface, and the nano metal probe is visited including metal Pin body and the thorn-like projection for being distributed in metal probe body surface, the thorn-like is raised and its surrounding is attached with detection cause of disease The antibody molecule of body, the antibody molecule is at least one of DNA molecular, RNA molecule and immobilised enzymes molecule.
The Cleaning Principle of blood examination chip is in the present invention:Attract and capture to deposit in through blood sample by antibody molecule Pathogen molecule, and nano metal probe is then equivalent to microsensor, when the antibody molecule and cause of disease that are attached to its surface When body molecule is combined, nano metal probe can produce electric current, and pathogen molecule is determined according to the power of the electric current of generation Type.
Because all DNA fragmentations have excellent characteristics, optionally can closely it be tied with another segment DNA fragment Close.For example, the antibody molecule by designing and synthesizing high degree of specificity, the antibody molecule is attached on nano metal probe, The DNA molecular of staphylococcus aureus present in menses is caught with this, when the antibody molecule and the DNA of staphylococcus aureus When molecule is combined, nano metal probe will produce electric current.
In addition, immobilised enzymes molecule can also be adhered in the present invention to detect the component target in menses, such as in nanometer Adhere to the glucose oxidase of solidification on metal probe, for measuring the concentration of glucose in blood;On nano metal probe Adhere to the LO of solidification, for measuring the concentration of lactic acid in blood;The courage for adhering to solidification on nano metal probe is consolidated Alcohol oxidase and cholesterol ester hydrolase, for measuring the concentration of Blood Cholesterol;Adhere to solidification on nano metal probe B- HBDs and reducibility coenzyme, for measuring the concentration of ketoboidies in blood.Its principle is that these immobilised enzymes divide With the material such as the blood glucose in blood, cholesterol, lactic acid, ketoboidies redox reaction occurs for son respectively, produces oxidation current, therefore The concentration of the materials such as Blood Glucose, cholesterol, lactic acid and ketoboidies can be determined by the size for measuring electric current.
It should be noted that the present invention can set multiple nano metal probe structures on the surface of carrier substrate, every Different types of antibody molecule is adsorbed on individual nano metal probe.So, as soon as only needing bleed sample, energy on blood examination chip Multiple pathogens are analyzed, and most methods are once only capable of detecting a kind of pathogen molecule.
Inventor has found that a drop is through the quantity levels of pathogen molecule in blood sample and doctor's syringe needle in research process The blood sample of taking-up is suitable.In this case, a pathogen molecule of the drop through blood sample is typically less than 1000, even Less.Even if having adjusted the quantity of pathogen molecule, its quantity in through blood sample is set to reach million ranks, the electricity detected Flow signal also fainter.Pass through the peptizaiton that thorn-like is raised so that have bigger space around antibody molecule, carry disease The liquid of substance molecule flows through these spaces and is also easier to, so, and antibody molecule and pathogen molecule also just have much more machine It can be in contact with each other, so as to effectively improve sensitivity and the accuracy of detection.
Improved as a kind of of intelligent menstrual cup of the invention, the thorn-like is raised and its surrounding is also attached with metallic molecule Ruthenium.Wherein, metallic molecule ruthenium because ruthenium carries the positive charge of a unit, therefore can be adsorbed equivalent to the effect of amplifier On pathogen molecule with a negative electrical charge;So, the complex of ruthenium and pathogen molecule is easy to from nano metal probe On seize electronics, so as to produce one electric current for being enough to detect.
Improved as a kind of of intelligent menstrual cup of the invention, the metal probe body includes being arranged in probe through hole Metal cartridge, and the hemispherical metallic substrates of insulation film surface are protruded from, the thorn-like projection is distributed in the hemispherical The surface of metallic substrates.Compared to square structure, the surface of metal probe body is designed to hemispherical dome structure, can so be had The surface area of effect increase metal probe, so as to be more beneficial for follow-up thorn-like raised " growth ", and antibody molecule attachment with It is scattered.
Improved as a kind of of intelligent menstrual cup of the invention, the raised height of the thorn-like is 1 ~ 100nm.If thorn-like is raised Height it is too small, then can not play a part of effectively disperseing antibody molecule;If the raised height of thorn-like is excessive, disperse antibody molecule Effect does not increase anti-drop, so can not only increase manufacturing cost, while can increase the volume of whole blood examination chip yet.
Improved as a kind of of intelligent menstrual cup of the invention, the preparation method of the blood examination chip comprises the following steps:
Step 1: carrying out surface cleaning processing to carrier substrate, conductive substrate and photoresist layer are then coated successively, then in purple It is exposed and develops under the irradiation of outer light, and unexposed conductive substrate is removed using metal etchants, with needed for is formed Circuitous pattern;
Step 2: stripping photolithography glue-line, and washing and drying treatment is carried out, the glue-line that insulate is then coated with, and insulation glue-line is entered Row gets through hole processing, obtains the chip substrate of the through hole containing probe;
Step 3: chip substrate is put into the electroplating bath containing metal salt solution, switch on power, electricity is carried out to probe through hole Plating, the voltage for control plating is 5 μ V ~ 500mV, and the electric current of plating is 0.01 μ A ~ 100mA, plating duration for 1 ~ 30min;
Step 4: after the completion of to be electroplated, 1 ~ 10h of vacuum drying is carried out at a temperature of 25 ~ 85 DEG C, obtaining surface distributed has thorn-like Raised nano metal probe;
Step 5: thorn-like it is raised and its around load detecting pathogen antibody molecule, be then packaged processing, that is, obtain Described blood examination chip.
Wherein, carrier substrate is silicon chip, graphene substrate or silicon carbide substrate, and it is excellent chip carrier, is High-precision blood examination chip provides important foundation;Insulation glue-line then plays insulation passivation, in order to nano metal probe Make;The conduction and detection connection of conductive substrate then for electric current.
It should be noted that in blood examination chip fabrication processes, the time of plating is crucial, if the overlong time of plating, The raised metal probe structure of thorn-like containing nanometer can not just be obtained;But the time of plating is too short, and metal probe structure just arrives nanometer Level just stops " growth ", can not equally obtain required nano metal probe.In addition, the control to electroplating voltage/electric current is also Of crucial importance, otherwise, electroplating voltage/electric current is too high or too low can not also to obtain required nano metal probe.
Improved as a kind of of intelligent menstrual cup of the invention, metal salt solution is by HAuCl described in step 34Pressed with HCl Volume ratio 1:(1~10)Mix, wherein HAuCl4Concentration be 5 ~ 100mmol/L, HCl concentration is 10 ~ 500mmol/L. Gold is the good conductor of electric current, therefore, and selection Nano-Au probe can effectively improve sensitivity and the accuracy of detection.
Improved as a kind of of intelligent menstrual cup of the invention, the cup outer wall is provided with some massage convex points and some micro- Chamber;The intellectual monitoring module also includes physical therapy chip, and the physical therapy chip is arranged in the microcavity, and the physical therapy chip is At least one of magnetic therapy chip, negative ion chip, Nano Silver chip, far infrared chip and activated carbon chip.Wherein, massage Salient point can play certain massage effect to the vagina of women;In addition, by setting one or more of different physical therapy chips, Magnetic therapy chip with healthcare function can be such as set, and the magnetostatic field of this magnetic material produces life when with human contact Thing magnetic, supplements magnetic energy, can promote body local microcirculation, improves biology enzyme and increases, increases the acidic materials of vaginal fluid, The magnetic therapy chip is typically made up of neodymium-iron-boron magnetic material, and carries out appropriate magnetize.Further, it is also possible to anion is set, it is remote The chip with anti-inflammatory or sterilizing function of infrared ray, Nano Silver, activated carbon etc.Wherein, multiple chips can be function one Combination cause or difference in functionality, main can calm alleviates the intense strain of female menstrual period, evades menstruation infection, goes Eliminate the unusual smell, and with bactericidal antiphlogistic effect, to build comfortable, pleasure a mental state to female pathology period.Therefore, this hair The collective effect of bright massage convex point and physical therapy chip can effectively alleviate the lower abdominal pain of menstrual period appearance, falling inflation;And compare In drug therapy, the setting of physical therapy chip can promote female body local microcirculation system, improve biology enzyme and increase, increase and The acidic materials of vaginal fluid are maintained, the balance of microcirculqtory system is maintained so that design of the invention more love women's Health.
Improved as a kind of of intelligent menstrual cup of the invention, the sensor is temperature sensor, humidity sensor, liquid level At least one of sensor, flow sensor, pressure sensor and heat-sensitive sensor.Its main function be to privates environment and Analysis and detection to menstrual blood physiological data.
A kind of as menstrual cup of the invention intelligent improves, the wireless communication module be bluetooth, RFID, Z-wave, At least one of HomeRF, ZigBee, UWB, NFC, IrDA and Wi-Fi.
Improved as a kind of of intelligent menstrual cup of the invention, the intelligent terminal is connected with cloud server, the intelligence Terminal is at least one of mobile phone, computer and wearable device.By the present invention in that intelligent terminal is connected with cloud server, , so as to set up individual database, can be so to customize in the future by each data Cun Chudao cloud servers for gathering and analyzing Personalized menstrual cup and medical diagnosis on disease provide important references.
A kind of as menstrual cup of the invention intelligent improves, and it is just pair and oblique by the inwall of runner that the valve includes two panels Upper to stretch out and in the flexible flap of " people " font closed butt joint, it is flat that flexible flap described in two panels forms docking at the middle part of runner Face, and the runner is blocked, the bottom of each flexible flap forms folding line by fluting, flexible when pressing the support handle Flap can bend along the folding line and turn on the runner.The flexible flap that two panels is stretched out obliquely is tight under normal conditions Tightly closed together effectively prevents menses from circulating, and when cup intracavitary extrudes formation one equipped with more menses and in human body During fixed pressure, pressure can be equally acted on flexible flap so that flexible flap closes even closer, effectively prevented The problem of leakage being produced when having certain pressure;And only need to pinch the support handle at flexible flap when needing and turning on runner, make Flexible flap in runner allows flexible flap to separate can to turn on runner along folding line deformation, every flexible flap is all designed with Folding line, effect is can to allow flexible flap all towards designed Direction distortion pinching when support handle allows flexible flap to deform, and allows shape Become effect and reach best condition, allow runner conduction amount to reach best effect.
Improved as a kind of of intelligent menstrual cup of the invention, two feel salient points be arranged with the outer wall of the support handle, When pressing the feel salient point, flexible flap can bend along the folding line and turn on the runner.
Improved as a kind of of intelligent menstrual cup of the invention, the section of the folding line is V-shaped, and folding line is located at the flexible valve The middle part of valve.
Improved as a kind of of intelligent menstrual cup of the invention, the cup is provided with bulge loop in the inner side of rounded opening edge. The effect of inner side bulge loop is the tensioning elastic force for improving circular open so that menstrual cup can preferably open guarantor after human body is put into Holding original shape, and improve circular open and the identical dynamics of uterine neck prevents the phenomenon of leakage;Bulge loop is located in circular open Side is advantageous in that, when reducing menstrual cup push-in intravaginal and vaginal wall friction, and menstrual cup is is placed on women for a long time The article of intravaginal, outer lug ring is easier to cause the sense of discomfort of vagina, and inner process structure can avoid completely it is this Phenomenon, and the uterine neck that can preferably coincide so that the usage experience of user is more preferable.
Improve, heaved laterally in the middle part of the wall of cup of the cup as a kind of of intelligent menstrual cup of the invention, and in wall of cup Medium position be provided around the outer shroud of cup.Outer ring structure is designed to so that menstrual cup is difficult after inside of human body is put into The phenomenon for walking and releasing is produced, there is more preferable positioning action.
Improved as a kind of of intelligent menstrual cup of the invention, the bottom of the cup chamber is provided with the accommodating intellectual monitoring mould The neck of block.
Improved as a kind of of intelligent menstrual cup of the invention, the silica gel system that the cup, support handle and valve are formed in one Part.
The beneficial effects of the present invention are:The present invention does not only have the function of general menstrual cup and merges advanced electronic section Skill technology, menses testing result, and energy can be provided by the blood examination chip in menstrual cup within several minutes even several seconds Testing result by wireless communication module is sent to intelligent terminal in time, the interpretation of result of specialty is obtained, so as to allow user The health status of oneself can be known in time, to carry out timely prevention from suffering from the diseases or treatment;Eliminate usually to hospital simultaneously The trouble taken a blood sample, this highly shortened detection treatment between interval time so that user can quickly, Diagnostic data, and the blood examination conventional compared to hospital are obtained at low cost, and the blood examination chip causes detection more convenient, higher Effect;In addition, the present invention can monitor the amount of menses in menstrual cup by liquid level and flow sensor, and reminded by intelligent terminal User is discharged in the suitable time;Moreover, it is also possible to by setting the sensor of difference in functionality to recognize the color of menses, PH value, and the physiological data such as bacterial concentration, and the data of collection are sent to intelligent terminal by wireless communication module, by entering Row data com-parison and analysis can be inferred that the physiological status of user, if it find that physiology have will be reminded during exception user and When go examination in hospital to treat, full-scope safeguards women's health.
Brief description of the drawings
Fig. 1 is structural representation of the invention.
Fig. 2 is workflow diagram of the invention.
Fig. 3 is the structural representation of blood examination chip in the present invention.
Fig. 4 is the longitudinal sectional view of blood examination chip in the present invention.
Fig. 5 is the structural representation in the present invention during blood examination detecting pathogen.
Fig. 6 is the structural representation of valve in the present invention.
Structural representations of the Fig. 7 for valve in the present invention in pressing during flexible flap conducting runner.
In figure:
1- cups;
11- glasss of chambers;12- is open;13- holds in the palm handle;14- runners;
15- valves;151- flexibility flaps;152- folding lines;153- feel salient points;
16- bulge loops;17- outer shrouds;18- massage convex points;19- microcavitys;20- necks;
2- intellectual monitoring modules;
21- blood examination chips;211- carrier substrates;212- conductive substrates;213- insulation glue-lines;214- probe through holes;215- nanometers Metal probe;2151- metal probe bodies;21511- metal cartridges;21512- metallic substrates;2152- thorn-likes are raised;2153- Antibody molecule;216- pathogen molecules;
22- sensors;23- physical therapy chips;24- data acquisition modules;25- wireless communication modules;
3- power modules;
4- intelligent terminals;
5- cloud servers.
Embodiment
With reference to the accompanying drawings and detailed description, the present invention and its advantageous effects are described in detail, still, The embodiment of the present invention is not limited to this.
As shown in Fig. 1 ~ 7, a kind of intelligent menstrual cup, including cup 1, intellectual monitoring module 2 and with intellectual monitoring module 2 power modules 3 being electrically connected with, the inside of cup 1 has cup chamber 11, and cup 1 has circular open 12 at the top of cup chamber 11, Cup 1 is provided with bulge loop 16 in the inner side at the edge of circular open 12;The bottom of cup 1 is provided with support handle 13 in the offside of circular open 12 With the neck 20 of accommodating intellectual monitoring module 2, the inside of support handle 13 is provided with the runner 14 turned on cup chamber 11, and runner 14 is provided with control The valve 15 that runner 14 is turned on, the silica gel product that cup 1, support handle 13 and valve 15 are formed in one.
Wherein, heaved laterally in the middle part of the wall of cup of cup 1, and the outer shroud of cup 1 is provided around in the medium position of wall of cup 17;Being designed to of the structure of outer shroud 17, so that menstrual cup is not likely to produce the phenomenon for walking and releasing after inside of human body is put into, has more Good positioning action.
Wherein, the effect of circular open 12 is that menstrual cup causes cup 1 and vagina inner process after being put into women body Opening of the cervix match so that from opening of the cervix discharge menses can smoothly flow into glass chamber 11.The effect of inner side bulge loop 16 It is the tensioning elastic force for improving circular open 12 so that menstrual cup can preferably open the original shape of holding after human body is put into Shape, and improve circular open 12 and uterine neck dynamics of coincideing and prevent the phenomenon of leakage;Bulge loop 16 is located at the inner side of circular open 12 Be advantageous in that, reduce menstrual cup push-in intravaginal when and vaginal wall friction, and menstrual cup for for a long time be placed on vagina Interior article, outer lug ring is easier to cause the sense of discomfort of vagina, and inner process structure can avoid this phenomenon completely, And the uterine neck that can preferably coincide so that the usage experience of user is more preferable.
Wherein, an effect of support handle 13 is, after menstrual cup is pushed into intravaginal, and support handle 13 keeps being exposed at outside human body Face, when needing menstrual cup to be taken out from human body, can involve support handle 13 and easily take out menstrual cup;Another effect It is that can be flowed out when menstrual cup is built with menses from the port of support handle 13, it is not necessary to by menstrual cup from internal taking-up, reduce The frequently pollution from loading procedure again is taken out in human body.In addition, the valve 15 for being located at support handle 13 port is place when normal In closure state, the effect of valve 15 is to prevent the menses in glass chamber 11 from flowing out outside, and working as needs cup chamber 11 and runner 14 Only need to firmly tube squeezing valve 15 during interior menses discharge and make its deformation to turn on to flow out menses.
Intellectual monitoring module 2 includes that the blood examination chip 21 of menses can be detected, can monitor the sensing of the internal environment of glass chamber 11 Device 22, the data acquisition module 24 being electrically connected with respectively with blood examination chip 21 and sensor 22 and by gathered data to intelligence The wireless communication module 25 that terminal 4 is transmitted, makes intelligent terminal 4 be connected with cloud server 5, so will can every time gather and divide The data Cun Chudao cloud servers 5 of analysis, are to customize personalized menstrual cup and medical diagnosis on disease in the future so as to set up individual database Important references are provided.
Wherein, intelligent terminal 4 is at least one of mobile phone, computer and wearable device;Wireless communication module 25 is indigo plant At least one of tooth, RFID, Z-wave, HomeRF, ZigBee, UWB, NFC, IrDA and Wi-Fi;Sensor 22 is temperature At least one of sensor, humidity sensor, liquid level sensor, flow sensor, pressure sensor and heat-sensitive sensor, its Main function is the analysis and detection to privates environment and to menstrual blood physiological data.
Wherein, blood examination chip 21 is arranged on the inwall of glass chamber 11 and/or the inwall of runner 14, and the blood examination chip 21 can be carried out Real-time menses inspection, can provide menses testing result within several minutes even several seconds.So as to allow user can and Shi Zhixiao oneself health status, to carry out timely prevention from suffering from the diseases or treatment, while eliminating hospital carries out blood drawing inspection The trouble looked into, this highly shortened the interval time between detection and treatment so that user can obtain quickly, at low cost Diagnostic data, and the blood examination conventional compared to hospital are taken, the blood examination chip 21 causes detection more convenient, more efficient.
Sensor 22 can be arranged on the neck 20, the outer wall of cup chamber 11 or the outer wall of runner 14 of the bottom of glass chamber 11, pass through sensing Device 22 can monitor the amount of menses in menstrual cup, and remind user to be discharged in the suitable time by intelligent terminal 4;And And, can also by setting the sensor 22 of difference in functionality to recognize the color of menses, pH value, and the physiological data such as bacterial concentration, And the data of collection are sent to intelligent terminal 4 by wireless communication module 25, relatively it may infer that by carrying out data analysis Go out the physiological status of user, user will be reminded to go examination in hospital to treat in time during exception if it find that physiology has, comprehensively Ensure women's health.
As the preferred scheme of the present invention, as shown in Fig. 3 ~ 5, blood examination chip 21 includes carrier substrate 211, is arranged at carrier The conductive substrate 212 of substrate 211 and the insulation glue-line 213 for being covered in conductive substrate 212, insulation glue-line 213 offer probe Through hole 214, probe through hole 214 is provided with the nano metal probe 215 for protruding from insulation glue-line 213 surface, nano metal probe 215 include metal probe body 2151 and are distributed in the thorn-like projection 2152 on the surface of metal probe body 2151, and thorn-like is raised 2152 and its surrounding be attached with the antibody molecule 2153 of detection pathogen, antibody molecule 2153 is DNA molecular, RNA molecule and solid Surely at least one of enzyme molecule is changed.
The Cleaning Principle of blood examination chip 21 is in the present invention:Being attracted by antibody molecule 2153 and captured may be through blood sample Pathogen molecule 216 present in this, and nano metal probe 215 is then equivalent to microsensor, when being attached to the anti-of its surface Body molecule 2153 is when pathogen molecule 216 is combined, and nano metal probe 215 can produce electric current, according to the electric current of generation Power determines the type of pathogen molecule 216.
Because all DNA fragmentations have excellent characteristics, optionally can closely it be tied with another segment DNA fragment Close.For example, the antibody molecule 2153 by designing and synthesizing high degree of specificity, nano metal is attached to by the antibody molecule 2153 On probe 215, the DNA molecular of staphylococcus aureus present in menses is caught with this, when the antibody molecule 2153 with it is golden yellow When the staphylococcic DNA molecular of color is combined, nano metal probe 215 will produce electric current.
In addition, immobilised enzymes molecule can also be adhered in the present invention to detect the component target in menses, such as in nanometer Adhere to the glucose oxidase of solidification on metal probe 215, for measuring the concentration of glucose in blood;In nano metal probe Adhere to the LO of solidification on 215, for measuring the concentration of lactic acid in blood;Adhere on nano metal probe 215 solid The cholesterol oxidase and cholesterol ester hydrolase of change, for measuring the concentration of Blood Cholesterol;In nano metal probe 215 The b- HBDs and reducibility coenzyme of upper attachment solidification, for measuring the concentration of ketoboidies in blood.Its principle is, these With the material such as the blood glucose in blood, cholesterol, lactic acid, ketoboidies redox reaction occurs for immobilised enzymes molecule respectively, produces oxygen Galvanic current, therefore the dense of the materials such as Blood Glucose, cholesterol, lactic acid and ketoboidies can be determined by the size for measuring electric current Degree.
It should be noted that the present invention can set multiple knots of nano metal probe 215 on the surface of carrier substrate 211 Structure, adsorbs different types of antibody molecule 2153 on each nano metal probe 215.So, on blood examination chip 21 As soon as only needing sample of bleeding, multiple pathogens can be analyzed, and most methods are once only capable of detecting a kind of pathogen molecule 216.
Inventor has found that a drop is used through the quantity levels of pathogen molecule 216 in blood sample and doctor in research process The blood sample that syringe needle takes out is suitable.In this case, a pathogen molecule 216 of the drop through blood sample is typically less than 1000 It is individual, or even less.Even if having adjusted the quantity of pathogen molecule 216, its quantity in through blood sample is set to reach million ranks, The current signal detected is also fainter.Pass through the peptizaiton of thorn-like projection 2152 so that have around antibody molecule 2153 Bigger space, the liquid that carry pathogen molecule 216 flows through these spaces and is also easier to, so, the He of antibody molecule 2153 Pathogen molecule 216 also just has much more chance to be in contact with each other, so as to effectively improve sensitivity and the accuracy of detection.
As the preferred scheme of the present invention, thorn-like is raised and its surrounding is also attached with metallic molecule ruthenium.Wherein, metallic molecule Ruthenium because positive charge of the ruthenium with unit, therefore can be adsorbed with negative electrical charge equivalent to the effect of amplifier On pathogen molecule 216;So, the complex of ruthenium and pathogen molecule 216 is easy to seize electricity from nano metal probe 215 Son, so as to produce one electric current for being enough to detect.
As the preferred scheme of the present invention, metal probe body 2151 includes the metal column being arranged in probe through hole 214 Body 21511, and the hemispherical metallic substrates 21512 on insulation glue-line 213 surface are protruded from, thorn-like projection 2152 is distributed in hemisphere The surface of shape metallic substrates 21512.Compared to square structure, the surface of metal probe body 2151 is designed to hemispherical junction Structure, can so be effectively increased the surface area of metal probe, so that " growth " of follow-up thorn-like projection 2152 is more beneficial for, and The attachment of antibody molecule 2153 and scattered.
As the preferred scheme of the present invention, the height of thorn-like projection 2152 is 1 ~ 100nm.If the height of thorn-like projection 2152 It is too small, then it can not play a part of effectively disperseing antibody molecule 2153;If the height of thorn-like projection 2152 is excessive, disperse antibody point Sub 2153 effects do not increase anti-drop, so can not only increase manufacturing cost, while can increase the volume of whole blood examination chip 21 yet.
As the preferred scheme of the present invention, the preparation method of blood examination chip 21 comprises the following steps:
Step 1: carrying out surface cleaning processing to carrier substrate 211, conductive substrate 212 and photoresist layer are then coated successively, is connect And be exposed and develop under the irradiation of ultraviolet light, and unexposed conductive substrate 212 is removed using metal etchants, with shape Into required circuitous pattern;Wherein, conductive substrate 212 is conductive metal layer, preferably layer gold or layers of copper, and photoresist layer is preferred SU-8 photoresists;
Step 2: stripping photolithography glue-line, and washing and drying treatment is carried out, the glue-line 213 that insulate is then coated with, and to insulation glue-line 213 carry out getting through hole processing, obtain the chip substrate of through hole containing probe 214;Wherein, insulation glue-line 213 is novolac resin layer, ring Oxygen tree lipid layer, polyimide resin layer, polyester resin layer, polyphenylene oxide resin layer, cyanate resin lipid layer or polyflon Layer;
Step 3: chip substrate is put into the electroplating bath containing metal salt solution, switch on power, probe through hole 214 is carried out Plating, the voltage for control plating is 5 μ V ~ 500mV, and the electric current of plating is 0.01 μ A ~ 100mA, plating duration for 1 ~ 30min;
Step 4: after the completion of to be electroplated, 1 ~ 10h of vacuum drying is carried out at a temperature of 25 ~ 85 DEG C, obtaining surface distributed has thorn-like The nano metal probe 215 of projection 2152;
Step 5: thorn-like projection 2152 and its around load detecting pathogen antibody molecule 2153, be then packaged place Reason, that is, the blood examination chip 21 obtained.
Wherein, carrier substrate 211 is silicon chip, graphene substrate or silicon carbide substrate, and it is excellent chip carrier, Important foundation is provided for high-precision blood examination chip 21;Insulation glue-line 213 then plays insulation passivation, in order to nano metal The making of probe 215;The conduction and detection connection of conductive substrate 212 then for electric current.
It should be noted that in the manufacturing process of blood examination chip 21, the time of plating is crucial, if the time mistake of plating It is long, it can not just obtain the metal probe structure of the projection of thorn-like containing nanometer 2152;But the time of plating is too short, and metal probe structure is firm Just stop " growing " to nanoscale, can not equally obtain required nano metal probe 215.In addition, to electroplating voltage/electric current Control is also of crucial importance, and otherwise, electroplating voltage/electric current is too high or too low can not also to obtain required nano metal probe 215.
As the preferred scheme of the present invention, metal salt solution is by HAuCl in step 34With HCl by volume 1:(1~10) Mix, wherein HAuCl4Concentration be 5 ~ 100mmol/L, HCl concentration is 10 ~ 500mmol/L.Gold is the good of electric current Conductor, therefore, selection Nano-Au probe can effectively improve sensitivity and the accuracy of detection.
As the preferred scheme of the present invention, the outer wall of cup 1 is provided with some massage convex points 18 and some microcavitys 19;Intelligence prison Surveying module 2 also includes physical therapy chip 23, and physical therapy chip 23 is arranged in microcavity 19, and physical therapy chip 23 is magnetic therapy chip, anion At least one of chip, Nano Silver chip, far infrared chip and activated carbon chip.Wherein, massage convex point 18 can be to female The vagina of property plays certain massage effect;In addition, by setting one or more of different physical therapy chips 23, such as can set The magnetic therapy chip with healthcare function is put, the magnetostatic field of this magnetic material produces biological magnetic when with human contact, supplements magnetic Energy, can promote body local microcirculation, improve biology enzyme and increase, increase the acidic materials of vaginal fluid, the magnetic therapy chip Typically it is made up of neodymium-iron-boron magnetic material, and carries out appropriate magnetize.Further, it is also possible to set anion, far infrared, nanometer The chip with anti-inflammatory or sterilizing function of silver, activated carbon etc.Wherein, multiple chips can be that function is consistent, can also It is the combination of difference in functionality, main can calm alleviates the intense strain of female menstrual period, evades menstruation infection, goes to eliminate the unusual smell, and have There is bactericidal antiphlogistic effect, to build comfortable, pleasure a mental state to female pathology period.Therefore, massage convex point of the present invention 18 and physical therapy chip 23 collective effect can effectively alleviate the menstrual period appearance lower abdominal pain, falling inflation;And compared to medicine Treatment, the setting of physical therapy chip 23 can promote female body local microcirculation system, improve biology enzyme and increase, increase and maintenance The acidic materials of vaginal fluid, maintain the balance of microcirculqtory system so that the health of women is more cared about in design of the invention.
As the preferred scheme of the present invention, as shown in fig. 6, to include two panels just pair and oblique by the inwall of runner 14 for valve 15 Upper to stretch out and in the flexible flap 151 of " people " font closed butt joint, two panels flexibility flap 151 forms docking at the middle part of runner 14 Plane, and runner 14 is blocked, the bottom of each flexible flap 151 forms folding line 152 by fluting, flexible during pressing support handle 13 Flap 151 can bend along folding line 152 and turn on runner 14.The flexible flap 151 that two panels is stretched out obliquely is under normal conditions It is that tightly closed together effectively prevents menses from circulating, and when cup chamber 11 is extruded built with more menses and in human body When forming certain pressure, pressure, which can be equally acted on flexible flap 151, causes flexibility flap 151 to close even closer, It is effective to prevent from producing the problem of leaking when there is certain pressure;And only need to pinch flexible valve when needing conducting runner 14 Support handle 13 at valve 151 so that the flexible flap 151 in runner 14 allows flexible flap 151 to separate along the deformation of folding line 152 Turn on runner 14, every flexible flap 151 is all designed with folding line 152, effect is when pinching support handle 13 and allowing flexible flap 151 to deform Flexible flap 151 can be allowed all towards designed Direction distortion, allow deformation effects to reach best condition, the conduction amount of runner 14 is allowed Reach best effect.
As the preferred scheme of the present invention, as shown in fig. 7, two feel salient points 153 are arranged with the outer wall of support handle 13, When pressing feel salient point 153, flexible flap 151 can bend along folding line 152 and turn on runner 14;The section of folding line 152 is V-shaped, And folding line 152 is located at the middle part of flexible flap 151.
The announcement and teaching of book according to the above description, those skilled in the art in the invention can also be to above-mentioned embodiment party Formula is changed and changed.Therefore, the invention is not limited in above-mentioned embodiment, every those skilled in the art exist Made any conspicuously improved, replacement or modification belong to protection scope of the present invention on the basis of the present invention.This Outside, although having used some specific terms in this specification, these terms merely for convenience of description, not to the present invention Constitute any limitation.

Claims (10)

1. a kind of intelligent menstrual cup, including cup, intellectual monitoring module and the power supply mould being electrically connected with intellectual monitoring module Block, the inside of the cup has cup chamber, and cup has circular open at the top of cup chamber, and the bottom of cup is opened in the circle The offside of mouth is provided with holding in the palm provided with the runner with cup chamber conducting inside handle, the support handle, and the runner is provided with the control stream The valve of road conducting, it is characterised in that:The intellectual monitoring module includes that the blood examination chip of menses can be detected, can monitor a glass chamber The sensor of internal environment, the data acquisition module being electrically connected with respectively with the blood examination chip and the sensor and general The wireless communication module that gathered data is transmitted to intelligent terminal.
2. intelligent menstrual cup according to claim 1, it is characterised in that:The blood examination chip includes carrier substrate, set In the carrier substrate conductive substrate and be covered in the insulation glue-line of the conductive substrate, the insulation glue-line is offered Probe through hole, the probe through hole is provided with the nano metal probe for protruding from insulation film surface, the nano metal probe Raised including metal probe body and the thorn-like for being distributed in metal probe body surface, the thorn-like is raised and its surrounding is adhered to There is the antibody molecule of detection pathogen, the antibody molecule is at least one in DNA molecular, RNA molecule and immobilised enzymes molecule Kind.
3. intelligent menstrual cup according to claim 2, it is characterised in that:The metal probe body includes being arranged at probe Metal cartridge in through hole, and the hemispherical metallic substrates of insulation film surface are protruded from, the thorn-like projection is distributed in institute State the surface of hemispherical metallic substrates.
4. intelligent menstrual cup according to claim 2, it is characterised in that:The raised height of the thorn-like is 1 ~ 100nm.
5. intelligent menstrual cup according to claim 2, it is characterised in that the preparation method of the blood examination chip includes following Step:
Step 1: carrying out surface cleaning processing to carrier substrate, conductive substrate and photoresist layer are then coated successively, then in purple It is exposed and develops under the irradiation of outer light, and unexposed conductive substrate is removed using metal etchants, with needed for is formed Circuitous pattern;
Step 2: stripping photolithography glue-line, and washing and drying treatment is carried out, the glue-line that insulate is then coated with, and insulation glue-line is entered Row gets through hole processing, obtains the chip substrate of the through hole containing probe;
Step 3: chip substrate is put into the electroplating bath containing metal salt solution, switch on power, electricity is carried out to probe through hole Plating, the voltage for control plating is 5 μ V ~ 500mV, and the electric current of plating is 0.01 μ A ~ 100mA, plating duration for 1 ~ 30min;
Step 4: after the completion of to be electroplated, 1 ~ 10h of vacuum drying is carried out at a temperature of 25 ~ 85 DEG C, obtaining surface distributed has thorn-like Raised nano metal probe;
Step 5: thorn-like it is raised and its around load detecting pathogen antibody molecule, be then packaged processing, that is, obtain Described blood examination chip.
6. intelligent menstrual cup according to claim 5, it is characterised in that:Metal salt solution is by HAuCl described in step 34 With HCl by volume 1:(1~10)Mix, wherein HAuCl4Concentration be 5 ~ 100mmol/L, HCl concentration for 10 ~ 500mmol/L。
7. intelligent menstrual cup according to claim 1, it is characterised in that:The cup outer wall is provided with some massage convex points With some microcavitys;The intellectual monitoring module also includes physical therapy chip, and the physical therapy chip is arranged in the microcavity, the reason Treatment chip is at least one of magnetic therapy chip, negative ion chip, Nano Silver chip, far infrared chip and activated carbon chip.
8. intelligent menstrual cup according to claim 1, it is characterised in that:The sensor is temperature sensor, humidity biography At least one of sensor, liquid level sensor, flow sensor, pressure sensor and heat-sensitive sensor;The radio communication mold Block is at least one of bluetooth, RFID, Z-wave, HomeRF, ZigBee, UWB, NFC, IrDA and Wi-Fi.
9. intelligent menstrual cup according to claim 1, it is characterised in that:The intelligent terminal is connected with cloud server, The intelligent terminal is at least one of mobile phone, computer and wearable device.
10. intelligent menstrual cup according to claim 1, it is characterised in that:The valve includes inwall of the two panels by runner Stretch out just pair and obliquely and in the flexible flap of " people " font closed butt joint, middle part shape of the flexible flap in runner described in two panels Into docking plane, and the runner is blocked, the bottom of each flexible flap forms folding line by fluting, presses the support handle When, flexible flap can bend along the folding line and turn on the runner.
CN201710336783.4A 2017-05-14 2017-05-14 Intelligent menstrual cup Pending CN107049587A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710336783.4A CN107049587A (en) 2017-05-14 2017-05-14 Intelligent menstrual cup

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710336783.4A CN107049587A (en) 2017-05-14 2017-05-14 Intelligent menstrual cup

Publications (1)

Publication Number Publication Date
CN107049587A true CN107049587A (en) 2017-08-18

Family

ID=59597277

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710336783.4A Pending CN107049587A (en) 2017-05-14 2017-05-14 Intelligent menstrual cup

Country Status (1)

Country Link
CN (1) CN107049587A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108210152A (en) * 2018-02-12 2018-06-29 深圳爱感科技有限公司 A kind of menstrual cup
KR101901452B1 (en) 2018-01-16 2018-09-27 김근배 Disposable pumping menstrual cups which are housed so that the remains of menstrual blood are not left
KR20190105743A (en) * 2018-03-06 2019-09-18 박미려 Menses collection device
KR101991669B1 (en) * 2017-12-18 2019-09-30 두재균 Combined structure of menstrual discharge part and discharge part
CN111358616A (en) * 2020-01-23 2020-07-03 唐志 Moon cup and plug thereof
CN111358615A (en) * 2020-01-23 2020-07-03 唐志 Lunar affair cup and switch accessory thereof
KR20210053617A (en) * 2019-11-04 2021-05-12 주식회사 스탠다드파크 Smart menstrual cup
WO2022225070A1 (en) * 2021-04-19 2022-10-27 주식회사 스탠다드파크 Smart menstrual cup

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1681938A (en) * 2002-07-20 2005-10-12 美国艾森生物科学公司 Testing apparatuses and methods based impedance
CN101078026A (en) * 2006-05-24 2007-11-28 江苏吴中高新技术实业有限公司 DNA electrochemical sensor and preparation method thereof
CN101812529A (en) * 2010-04-23 2010-08-25 中国科学院上海微系统与信息技术研究所 Nanometer compound probe and detection method thereof for gene chip film transfer print
CN101884898A (en) * 2004-07-08 2010-11-17 株式会社山武 The method of biochip substrate and the substrate of manufacturing biochip
CN102216762A (en) * 2008-09-02 2011-10-12 多伦多大学董事局 Nanostructured microelectrodes and biosensing devices incorporating the same
CN104280365A (en) * 2014-07-10 2015-01-14 深圳威芯华创科技有限公司 Dual-detection biosensing chip and preparation method thereof and DNA detection method
CN204319019U (en) * 2014-11-25 2015-05-13 广州天沅硅胶机械科技有限公司 The menstruation ball of medicine carrying
CN104937109A (en) * 2012-09-12 2015-09-23 艾克泽基因公司 Systems, devices, and methods for identifying a disease state in a biological host using internal controls
CN105287086A (en) * 2015-11-26 2016-02-03 广州天沅硅胶机械科技有限公司 Intelligent menstrual cup
CN205144836U (en) * 2015-10-15 2016-04-13 广州天沅硅胶机械科技有限公司 Menstruation cup with outer loop
CN105593409A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Sensor growth controller
CN105593379A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Systems, methods and devices for electrochemical detection using helper oligonucleotides
CN105593332A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Microchip structure and treatments for electrochemical detection
CN106324058A (en) * 2016-08-09 2017-01-11 济南大学 Preparation method and application of high-sensitivity non-enzyme electrochemical immunosensor
CN106645346A (en) * 2016-11-14 2017-05-10 中国科学院电子学研究所 Multi-site detection region, microelectrode array and preparation method thereof

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1681938A (en) * 2002-07-20 2005-10-12 美国艾森生物科学公司 Testing apparatuses and methods based impedance
CN101884898A (en) * 2004-07-08 2010-11-17 株式会社山武 The method of biochip substrate and the substrate of manufacturing biochip
CN101078026A (en) * 2006-05-24 2007-11-28 江苏吴中高新技术实业有限公司 DNA electrochemical sensor and preparation method thereof
CN102216762A (en) * 2008-09-02 2011-10-12 多伦多大学董事局 Nanostructured microelectrodes and biosensing devices incorporating the same
CN101812529A (en) * 2010-04-23 2010-08-25 中国科学院上海微系统与信息技术研究所 Nanometer compound probe and detection method thereof for gene chip film transfer print
CN104937109A (en) * 2012-09-12 2015-09-23 艾克泽基因公司 Systems, devices, and methods for identifying a disease state in a biological host using internal controls
CN105593409A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Sensor growth controller
CN105593332A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Microchip structure and treatments for electrochemical detection
CN105593379A (en) * 2013-08-07 2016-05-18 艾克泽基因公司 Systems, methods and devices for electrochemical detection using helper oligonucleotides
CN104280365A (en) * 2014-07-10 2015-01-14 深圳威芯华创科技有限公司 Dual-detection biosensing chip and preparation method thereof and DNA detection method
CN204319019U (en) * 2014-11-25 2015-05-13 广州天沅硅胶机械科技有限公司 The menstruation ball of medicine carrying
CN205144836U (en) * 2015-10-15 2016-04-13 广州天沅硅胶机械科技有限公司 Menstruation cup with outer loop
CN105287086A (en) * 2015-11-26 2016-02-03 广州天沅硅胶机械科技有限公司 Intelligent menstrual cup
CN106324058A (en) * 2016-08-09 2017-01-11 济南大学 Preparation method and application of high-sensitivity non-enzyme electrochemical immunosensor
CN106645346A (en) * 2016-11-14 2017-05-10 中国科学院电子学研究所 Multi-site detection region, microelectrode array and preparation method thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101991669B1 (en) * 2017-12-18 2019-09-30 두재균 Combined structure of menstrual discharge part and discharge part
KR101901452B1 (en) 2018-01-16 2018-09-27 김근배 Disposable pumping menstrual cups which are housed so that the remains of menstrual blood are not left
CN108210152A (en) * 2018-02-12 2018-06-29 深圳爱感科技有限公司 A kind of menstrual cup
KR20190105743A (en) * 2018-03-06 2019-09-18 박미려 Menses collection device
KR102029067B1 (en) * 2018-03-06 2019-11-08 박미려 Menses collection device
KR20210053617A (en) * 2019-11-04 2021-05-12 주식회사 스탠다드파크 Smart menstrual cup
KR102262918B1 (en) * 2019-11-04 2021-06-09 주식회사 스탠다드파크 Smart menstrual cup
CN111358616A (en) * 2020-01-23 2020-07-03 唐志 Moon cup and plug thereof
CN111358615A (en) * 2020-01-23 2020-07-03 唐志 Lunar affair cup and switch accessory thereof
WO2022225070A1 (en) * 2021-04-19 2022-10-27 주식회사 스탠다드파크 Smart menstrual cup

Similar Documents

Publication Publication Date Title
CN107049587A (en) Intelligent menstrual cup
CN106983603A (en) Intelligent sanitary napkins
Zhang et al. Wearable Internet of Things enabled precision livestock farming in smart farms: A review of technical solutions for precise perception, biocompatibility, and sustainability monitoring
US9107776B2 (en) Incontinence management system and diaper
Chen et al. Application of microfluidics in wearable devices
US20080266117A1 (en) Sensors and disposable articles that contain the sensors
CN107149524A (en) Intelligent sanitary sliver
CN101787730B (en) Intelligent water closet with automatic display of urine test information
US11045246B1 (en) Apparatus for effecting feedback of vaginal cavity physiology
CN107049604A (en) Intelligent adhesive bandage
CN106488739A (en) Health status monitoring equipment
CN104758123A (en) Intelligent sanitary towel and panty liner
CN107647869A (en) Repeatable wearable breathing detection instrument based on graphene electronic nose
CN105213083B (en) A kind of invalid diaper structure of incontinence
CN204972666U (en) Area is intelligent monitoring, accuse urine device and system of monitoring of urinary tract urine hydromechanics down
CN103654804B (en) Defecation awareness signal detecting and defecation awareness reestablishing system
CN110477930A (en) A kind of flexible wearable sensor for sweat detection
CN114098669A (en) Symmetric temperature difference personalized health management system-human body symmetric temperature difference CWPAS health management system and use method
CN105997027A (en) Wearable remote electrocardiogram monitoring system
CN104970805B (en) Percutaneous microneedle array patch and its manufacture method
CN107157640A (en) Intelligent sheath
CN110279912A (en) A kind of antiseep supplementary structure
CN204600909U (en) Intelligent sanitary napkins, protective pad
Bian et al. Application prospects for wearable body surface microfluidic system in sports
CN205486691U (en) Prevent pressing sore intelligence warning system

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170818