CN107049323A - A kind of quick mouse subcutaneous tumor volumes survey tool - Google Patents

A kind of quick mouse subcutaneous tumor volumes survey tool Download PDF

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Publication number
CN107049323A
CN107049323A CN201710328597.6A CN201710328597A CN107049323A CN 107049323 A CN107049323 A CN 107049323A CN 201710328597 A CN201710328597 A CN 201710328597A CN 107049323 A CN107049323 A CN 107049323A
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CN
China
Prior art keywords
measurement
folder
range finder
laser range
airborne laser
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710328597.6A
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Chinese (zh)
Inventor
陈传军
何远桥
肖秀清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanchang Royo Biotech Co Ltd
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Nanchang Royo Biotech Co Ltd
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Publication of CN107049323A publication Critical patent/CN107049323A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1072Measuring physical dimensions, e.g. size of the entire body or parts thereof measuring distances on the body, e.g. measuring length, height or thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1077Measuring of profiles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1079Measuring physical dimensions, e.g. size of the entire body or parts thereof using optical or photographic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/42Evaluating a particular growth phase or type of persons or animals for laboratory research

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The present invention discloses a kind of quick mouse subcutaneous tumor volumes survey tool, including measurement handle, measurement handle top limit position regulation chute, measurement sliding block is installed on spacing regulation chute, measure and L-shaped extension support arm is provided with front side of sliding block, fixed activity measurement folder on extension support arm, the opposite side of activity measurement folder is provided with the fixation measuring clamp for being fixed on measurement handle, the front of fixation measuring clamp is provided with the longitudinal airborne laser range finder of a row, and the folder inwall of the fixation measuring clamp is provided with horizontal airborne laser range finder, while activity measurement folder and fixed activity folder clamp mouse subcutaneous tumour, longitudinal airborne laser range finder and horizontal airborne laser range finder calculate the vertical direction maximum transverse diameter of tumour and the longest diameter in tumor levels direction respectively.The present invention solves conventional method using inconvenient operation in vernier caliper measurement gross tumor volume, the problem of data error is big, and whole compact volume and convenience, with low cost.

Description

A kind of quick mouse subcutaneous tumor volumes survey tool
Technical field
The present invention relates to the reality that mouse cell line in a kind of oncology correlative study is inoculated with into knurl model or Transplanted tumor model Test instrument, more particularly to a kind of quick mouse subcutaneous tumor volumes survey tool.
Background technology
At present, set up that the strain of mouse subcutaneous cell is inoculated with into knurl model or Transplanted tumor model is common in oncology correlative study A kind of technological means, by observing the growing state of mouse hypodermic tumour, deploy a series of scientific researches.See in current laboratory The growing state of mouse hypodermic tumour is examined mainly by rough measure and observation gross tumor volume.Conventional method is to use vernier calliper Chi record tumour longest diameter (L) and vertical direction maximum transverse diameter (W), according to formula V=LW2/ 2 calculate gross tumor volume.The method is grasped Although work is not difficult, measurement error is big, and time-consuming, generally requires two people's cooperations.Recent years abroad develops a kind of tumour tracking system System, can draw tumour 3D rendering in 0.1 second, and be calculated, and data accuracy is high, simple to operate, but price is very expensive.
The content of the invention
A kind of above-mentioned deficiency of the invention in order to solve prior art, it is proposed that quick mouse subcutaneous tumor volumes measurement work Tool.
In order to solve the above-mentioned technical problem, the present invention uses following technical scheme:A kind of quick mouse subcutaneous tumor volumes Survey tool, including measurement handle, the top of the measurement handle is provided with a spacing regulation chute, the spacing regulation chute On measurement sliding block is installed, L-shaped extension support arm, the front end lower side of the extension support arm are provided with front side of the measurement sliding block The fixed activity measurement folder in portion, the opposite side of the activity measurement folder is provided with the fixation measuring clamp for being fixed on measurement handle, The front of the fixation measuring clamp is arranged on longitudinal airborne laser range finder on the downside of measurement handle, and the fixation measuring clamp provided with a row Folder inwall be provided with the horizontal airborne laser range finder for being used for measuring spacing between fixed activity folder and activity measurement folder;The activity While measurement folder and fixed activity folder clamp mouse subcutaneous tumour, longitudinal airborne laser range finder and horizontal airborne laser range finder point The vertical direction maximum transverse diameter (W) of tumour and the longest diameter (L) in tumor levels direction are not calculated.
Further, the inside of the measurement handle is additionally provided with the computing controller of the volume for calculating tumour, institute State computing controller and be connected to longitudinal airborne laser range finder and horizontal airborne laser range finder.
Further, tumour (9) volumetric quantities is aobvious after the side of the measurement handle is calculated provided with one for display Display screen, the display screen is controlled to connect by the computing controller.
Further, the top of the measurement sliding block be provided be used to controlling computing controller start longitudinal airborne laser range finder and The start button of horizontal airborne laser range finder work.
Further, it is additionally provided with front side of the measurement handle before the guide chute of one section of transverse direction, the extension support arm End is inserted into guide pad in guide chute provided with matching.
Further, there is certain gap, longitudinal laser ranging between the activity measurement folder and measurement handle Device is placed between described gap, and the upside outer wall of activity measurement folder has the laser shadow shield laterally set.
The operation principle of the present invention is that the key for obtaining mouse subcutaneous tumor volumes rough figure is that acquisition tumour is most long straight Footpath (L) and vertical direction maximum transverse diameter (W) the two numerical value, based on this, using laser distance measuring principle, realize that the quick of data is obtained Take.Pass through, fixed activity folder determines the diameter of tumour with activity measurement clamp lock, and fixed activity is pressed from both sides and activity measurement folder must be vertical In tumour, fixed activity folder is most long straight to measure the distance between two necks, i.e. tumour provided with horizontal airborne laser range finder Footpath (L), that is, tumour diameter.
Longitudinal airborne laser range finder of top dense arrangement between fixed activity folder and activity measurement inner side sends infrared ray, Press in start button, infrared radiation to tumour.Because preferable tumour is a cambered surface, when infrared ray is impinged upon above, one The problem of a little infrared rays can be due to angle of reflection and can not backtracking generating laser, cause no data, still, actual situation It is that mouse hypodermic tumour is often no so regular, has several generating lasers and receive signal, preferably, impinge upon tumour highest The infrared ray of point should can be reflected back transmitter.Generating laser receives signal, and program calculates distance automatically, and therefrom Minimum value is filtered out, the vertical range at generating laser to neck tip is fixed value, and the value subtracts above-mentioned minimum value, i.e., For the height of tumour vertical direction maximum transverse diameter (W), that is, tumour.
The program of computing controller presses formula V=LW automatically after the two values are obtained2/ 2 are calculated, and by result Display is on a display screen.Also directly it can be connected with computer, by data inputting Microsoft Excel.
Compared with prior art, the present invention solve conventional method using operated in vernier caliper measurement gross tumor volume not side Just, the problem of data error is big, and whole compact volume and convenience, it is with low cost, the operating efficiency of laboratory technician can be significantly improved.
Brief description of the drawings
Fig. 1 is structural representation of the invention.
Embodiment
Invention is described in detail with reference to the accompanying drawings and examples.
As shown in figure 1, quick mouse subcutaneous tumor volumes survey tool proposed by the present invention, including measurement handle 1, measurement The top of handle 1 is provided with a spacing regulation chute 2, and spacing adjust is provided with measurement sliding block 3 on chute, the front side of measurement sliding block 3 Provided with L-shaped extension support arm 4, the fixed activity measurement folder 5 of front end downside end for the support arm 4 that protracts, activity measurement folder 5 Opposite side be provided with the fixation measuring clamp 6 for being fixed on measurement handle 1, the front of fixation measuring clamp 6 is arranged on measurement provided with a row Longitudinal airborne laser range finder 7 of the downside of handle 1, and the folder inwall of the fixation measuring clamp 6 is provided with and is used to measure 6 Hes of fixed activity folder The horizontal airborne laser range finder 8 of spacing between activity measurement folder 5;It is subcutaneous swollen that activity measurement folder 5 and fixed activity folder 6 clamp mouse While knurl 9, longitudinal airborne laser range finder 7 calculates the vertical direction maximum transverse diameter of tumour 9 with horizontal airborne laser range finder 8 respectively The W and longest diameter L in tumor levels direction.
The inside of measurement handle 1 is additionally provided with the computing controller of the volume for calculating tumour 9, computing controller difference It is connected to longitudinal airborne laser range finder 7 and horizontal airborne laser range finder 8.Measure the side of handle 1 is used to show after calculating provided with one The display screen 10 of the volumetric quantities of tumour 9, display screen 10 is controlled to connect by computing controller.The top of measurement sliding block 3, which is provided with, to be used for Computing controller is controlled to start the start button 11 that longitudinal airborne laser range finder 7 and horizontal airborne laser range finder 8 work.Measure handle 1 Front side be additionally provided with the guide chute 12 of one section of transverse direction, the front end of extension support arm 4 is inserted into guide chute 12 provided with matching leads To block 13.Activity measurement folder 5 and measurement handle 1 between have certain gap, the gap that longitudinal airborne laser range finder 7 is placed in it Between, and the upside outer wall of activity measurement folder 5 has the laser shadow shield 14 laterally set.
When specifically used, tumour is observed, range estimation finds the longest diameter of general tumour to position, then slides measurement and slide Block 3, while measurement sliding block 3 is slided in spacing regulation chute 2, allows fixed activity folder 6 and activity measurement folder 5 vertically to clamp Tumour 9, is clamped in the longest diameter of tumour 9 to position, presses start button, longitudinal airborne laser range finder 7 and horizontal laser ranging Device 8 works and carries out ranging to tumour, and computing controller now calculates the volume of tumour, and shows specific number in display screen Value.
Above-described embodiment only expresses the several embodiments of the present invention, and it describes more specific and detailed, but can not Therefore understands that being the limitation to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, On the premise of not departing from present inventive concept, various modifications and improvements can be made, these belong to protection scope of the present invention. Therefore, patent of the present invention and protection domain should be defined by appended claims.

Claims (6)

1. a kind of quick mouse subcutaneous tumor volumes survey tool, it is characterised in that:Including measurement handle(1), the measurement hand Handle(1)Top provided with spacing regulation chute(2), it is described it is spacing regulation chute on measurement sliding block is installed(3), it is described to survey Measure sliding block(3)Front side is provided with L-shaped extension support arm (4), the fixed work of front end downside end of the extension support arm (4) Dynamic to measure folder (5), the opposite side of the activity measurement folder (5), which is provided with, is fixed on measurement handle(1)Fixation measuring clamp (6), institute The front for stating fixation measuring clamp (6) is arranged on measurement handle provided with a row(1)Longitudinal airborne laser range finder (7) of downside, and this is solid The folder inwall of location survey amount folder (6) is provided with the transverse direction for being used to measure spacing between fixed activity folder (6) and activity measurement folder (5) and swashed Ligh-ranging device (8);While the activity measurement folder (5) and fixed activity folder (6) clamp the subcutaneous tumour of mouse (9), this is indulged The vertical direction maximum transverse diameter (W) of tumour (9) is calculated respectively to airborne laser range finder (7) and horizontal airborne laser range finder (8) and is swollen The longest diameter (L) of knurl horizontal direction.
2. quick mouse subcutaneous tumor volumes survey tool according to claim 1, it is characterised in that:The measurement handle (1)Inside be additionally provided with for calculate tumour (9) volume computing controller, the computing controller is connected to vertical To airborne laser range finder (7) and horizontal airborne laser range finder (8).
3. quick mouse subcutaneous tumor volumes survey tool according to claim 2, it is characterised in that:The measurement hand Handle(1)Side provided with one be used for show calculate after tumour (9) volumetric quantities display screen(10), the display screen(10)By The computing controller control connection.
4. quick mouse subcutaneous tumor volumes survey tool according to claim 3, it is characterised in that:The measurement sliding block (3)Top be provided with and be used to controlling computing controller to start longitudinal airborne laser range finder (7) and horizontal airborne laser range finder (8) works Start button(11).
5. quick mouse subcutaneous tumor volumes survey tool according to claim 1, it is characterised in that:The measurement handle (1)Front side be additionally provided with the guide chute of one section of transverse direction(12), the front end of the extension support arm (4) is inserted into guiding provided with matching Chute(12)Interior guide pad(13).
6. quick mouse subcutaneous tumor volumes survey tool according to claim 1, it is characterised in that:The activity measurement Press from both sides (5) and measurement handle(1)Between there is certain gap, longitudinal airborne laser range finder (7) is placed between described gap, And the upside outer wall of activity measurement folder (5) has the laser shadow shield laterally set(14).
CN201710328597.6A 2017-01-21 2017-05-11 A kind of quick mouse subcutaneous tumor volumes survey tool Pending CN107049323A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2017100432634 2017-01-21
CN201710043263 2017-01-21

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CN107049323A true CN107049323A (en) 2017-08-18

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107741183A (en) * 2017-10-31 2018-02-27 国网河南省电力公司检修公司 A kind of hot line maintenance insulation slide measure
CN110680555A (en) * 2019-11-12 2020-01-14 重庆医药高等专科学校 Nude mouse subcutaneous tumor forming device
CN118161151A (en) * 2024-05-14 2024-06-11 德阳市人民医院 Device for measuring size of subcutaneous malignant tumor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103027686A (en) * 2012-12-11 2013-04-10 谭文勇 Device for detecting shape of head and neck neoplasm and shapes of normal organs around head and neck neoplasm
CN104729586A (en) * 2015-03-23 2015-06-24 中国民航大学 Device for automatically measuring volume and weight of luggage at airport safety detection machine end
CN204881424U (en) * 2015-09-08 2015-12-16 刘云鹤 Tumour size measuring device
CN208435649U (en) * 2017-01-21 2019-01-29 南昌乐悠生物科技有限公司 A kind of quick mouse subcutaneous tumor volumes measuring tool

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103027686A (en) * 2012-12-11 2013-04-10 谭文勇 Device for detecting shape of head and neck neoplasm and shapes of normal organs around head and neck neoplasm
CN104729586A (en) * 2015-03-23 2015-06-24 中国民航大学 Device for automatically measuring volume and weight of luggage at airport safety detection machine end
CN204881424U (en) * 2015-09-08 2015-12-16 刘云鹤 Tumour size measuring device
CN208435649U (en) * 2017-01-21 2019-01-29 南昌乐悠生物科技有限公司 A kind of quick mouse subcutaneous tumor volumes measuring tool

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107741183A (en) * 2017-10-31 2018-02-27 国网河南省电力公司检修公司 A kind of hot line maintenance insulation slide measure
CN110680555A (en) * 2019-11-12 2020-01-14 重庆医药高等专科学校 Nude mouse subcutaneous tumor forming device
CN110680555B (en) * 2019-11-12 2021-06-01 重庆医药高等专科学校 Nude mouse subcutaneous tumor forming device
CN118161151A (en) * 2024-05-14 2024-06-11 德阳市人民医院 Device for measuring size of subcutaneous malignant tumor
CN118161151B (en) * 2024-05-14 2024-07-16 德阳市人民医院 Device for measuring size of subcutaneous malignant tumor

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