CN107041754A - Wireless pulse blood oxygen transducer transceiver chip - Google Patents

Wireless pulse blood oxygen transducer transceiver chip Download PDF

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Publication number
CN107041754A
CN107041754A CN201710411148.8A CN201710411148A CN107041754A CN 107041754 A CN107041754 A CN 107041754A CN 201710411148 A CN201710411148 A CN 201710411148A CN 107041754 A CN107041754 A CN 107041754A
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CN
China
Prior art keywords
module
blood oxygen
output end
input
pulse blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710411148.8A
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Chinese (zh)
Inventor
陈力颖
倪立强
王焱
汤勇
翦彦龙
谭康
张长胜
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Tianjin Polytechnic University
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Tianjin Polytechnic University
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Publication date
Application filed by Tianjin Polytechnic University filed Critical Tianjin Polytechnic University
Priority to CN201710411148.8A priority Critical patent/CN107041754A/en
Publication of CN107041754A publication Critical patent/CN107041754A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface

Abstract

The present invention provides a kind of wireless pulse blood oxygen transducer transceiver chip, belongs to microelectronics, the field such as optics and medical electronics, including power management module, pulse blood oxygen acquisition module, signal processing module and radio receiving transmitting module, are the cores of wireless pulse oximeter system;Wireless pulse oximeter system, which can be used for hindering the medium or short range wireless non-invasive of human body blood oxygen saturation and pulse information, to be gathered, there is Great significance to the development of modern medicine, wireless pulse blood oxygen transducer transceiver chip is intended to simply handle pulse and blood oxygen signal, as amplified, filter and denoising, then signal is sent to host computer port by RFID technique and analyzed and processed;Present invention combination integrated circuit technique, radio-frequency technique and biomedical electronics technology, are conducive to medical device miniaturization, intellectuality, facilitation, mitigate numerous and diverse operation significantly, medical personnel need to only pass through the simple training just light left-hand seat of energy, simple to operate.

Description

Wireless pulse blood oxygen transducer transceiver chip
Technical field
The present invention belongs to microelectronics, and the field such as optics and medical electronics is related to infrared induction detector device And technology, integrated circuit technique, radio-frequency technique and sensor technology, it is especially applicable to wireless pulse blood oxygen transducer transceiver Chip.
Background technology
21 century is the epoch that a scientific and technical innovation is continued to develop, and is also the epoch that an aging population is constantly highlighted. Everyone family has old man, and the health problem of the elderly always affects the heart of our young man, but in order to support the family Eke out a living, the younger generation under having under above having always, which has to hurry back and forth for life, ignores the health of the elderly, and the elderly Be reluctant to bother children for this, or even conceal itself state of an illness, when have to inspection in hospital when just find it is late.To avoid The generation of such accident, regularly physical examination is inevitable, and goes hospital's physical examination of registering to need the time, and the elderly is to ought Preceding medical progress and illegal quick left-hand seat, young man have to the time of taking out to accompany.So for current medical treatment Reform is imperative, and portable medical treatment detection device should be at the prostatitis of reform.
Since in 20th century, with the development of semiconductor technology, each electronic product is arisen at the historic moment:Computer, mobile phone is all kinds of Household electrical appliances, which are constantly continuously created, to be come, and facilitates the life of people.The appearance of all kinds of medical examination apparatus so that the state of an illness of people is obtained Early discovery early treatment, substantially increases the life-span of people.
Pulse signal is a kind of physiological signal for being used to diagnose human body diseases earliest, in China's long history of 5,000 years In, before western medicine and medical practitioners are not also introduced into China, doctor is to feel the pulse to make a definite diagnosis various diseases in other words by diagnosis by feeling the pulse, Here it is the traditional Chinese medicine of one of history culture essence of China.It can be seen that pulse signal is to include abundant Human Physiology and pathology Information, extraction and processing to pulse signal also have important directive significance and reference price to present clinical medicine Value.
Oxygen is the basis of vital movement, and anoxic is to cause the root of many diseases, and more universal illness is for example chronic low Blood oxygen disease, brain and the cardiovascular physiology such as blood supply insufficiency and post exercise fatigue and pathological phenomenon all have directly with human body oxygen content Relation, directly threatens the life of people when serious, blood oxygen saturation is the important physiological parameter for monitoring the ability that human body carries oxygen, is led to Crossing the monitoring to blood oxygen saturation can estimate the ability that human body carries oxygen.
It can be seen that the significance level of pulse and blood oxygen saturation for health, especially 21 century, intelligent electric The appearance of sub- product so that in place of science and technology further innovation, traditional pulse and the unavoidable Shortcomings of the acquisition mode of blood oxygen, no Accurately, the acquisition mode for having wound formula has been not suitable with the development of existing market gradually, especially when biomedical with semiconductor skill The convenient Medical Devices of new generation of a series of new are generated after the combination of art, wireless pulse BOLD contrast is just in this broomrape.
Prior art can't be perfect solution technical problem involved in the present invention, the present invention passes in wireless pulse blood oxygen Sensor transceiver chip can be well adapted for the market demand, and providing acp chip and one for wireless pulse BOLD contrast has practicality The technical scheme of value.
The content of the invention
In order to overcome the above-mentioned deficiencies of the prior art, the purpose of the present invention is sensed by providing a kind of wireless pulse blood oxygen Device transceiver chip, as the core component of wireless pulse BOLD contrast, to improve the technical problem of wireless pulse BOLD contrast, It is allowed to more intelligent, miniaturization and convenient practicality, preferably to meet the market requirement.
Hardware of the present invention is by pulse blood oxygen acquisition chip, power management chip, signal processing chip, RFID wireless transmission marks Label composition.
Technical scheme:Wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including power management Module, pulse blood oxygen acquisition module, signal processing module and radio receiving transmitting module.Power management module is connected with each module, is Each module provides the support of stable power supply;The output end of pulse blood oxygen acquisition module connects the input of signal processing module, The output end of signal processing module connects the input of radio receiving transmitting module, and radio receiving transmitting module utilizes digitized signal RFID technique, reader is sent to by label, and the signal received is passed to host computer by reader, and host computer is by signal solution Analyzed and processed after tune, draw the information of human pulse and blood oxygen saturation and show corresponding numerical value over the display, if Then alarm is sent in the presence of abnormal to user.
The power management module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that use 1.8 volts LVPS improves the endurance of chip to reduce chip power-consumption;Including Voltage stabilizing module, charging module and battery module, Power supply is provided for other modules to support;The output end of charging module connects the input of battery module, the output end of battery module Connect the input of Voltage stabilizing module.
The Voltage stabilizing module of described power management module uses low pressure difference linear voltage regulator LDO structures, including band-gap reference Voltage source, protection circuit, error amplifier, power tube and sampling resistor;The output end connection error of bandgap voltage reference is put The positive pole of big device, the intermediate ends of sampling resistor connect the negative pole of error amplifier, the output end connection power tube of error amplifier Grid, the source electrode connection power supply VCC of power tube, drain electrode connection output end, one end connection power supply VCC of protection circuit is another The grid of end connection power tube, one end connection ground GND of sampling resistor, other end connection output end.
The pulse blood oxygen acquisition module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including ripple A length of 660nm red light-emitting diode, wavelength is 940nm near infrared light emitting diode, photodetector and LED drivings Module.
The signal processing module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including electric current frequency Rate converter, Current Voltage modular converter, preamplifier, low pass filter, secondary amplification module, counter and analog-to-digital conversion Device;The output end of current frequency converter connects the input of Current Voltage modular converter, the output of Current Voltage modular converter The input of end connection preamplifier, the output end of preamplifier connects the input of low pass filter, low pass filter Output end connecting secondary amplification module input, the output end of secondary amplification module connects the input of analog-digital converter, The input of the output end linkage counter of analog-digital converter, and the input of connection radio receiving transmitting module, the output of counter The input of end connection radio receiving transmitting module.
The preamplifier of described signal processing module, it is characterised in that including three operational amplifiers, six accurate Resistance and a variable resistor, its yield value amplified can be adjusted by changing the resistance of variable resistor.
The radio receiving transmitting module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that use RFID skills Art, it is possible to achieve to the wireless transmission of the data obtained, matching reader can receive gained signal.
The present invention has the advantage that:1. the noninvasive collection of human body vital sign signal;2. chip is more intelligent, miniaturization And facilitation, operate simpler;3. the wireless penetration that information is sent, realizes indoor short-distance radio manipulation.
Brief description of the drawings
Fig. 1 is the composition frame chart of wireless pulse blood oxygen transducer transceiver chip of the present invention;
Fig. 2 is the configuration schematic diagram of wireless pulse blood oxygen transducer transceiver chip of the present invention;
Fig. 3 is that invasion of vessels of the present invention is fought the composition block diagram of blood oxygen acquisition module;
Fig. 4 is the composition block diagram of signal processing module in the present invention;
Fig. 5 is the circuit theory diagrams of the current-to-voltage convertor of signal processing module in the present invention;
Fig. 6 is the circuit theory diagrams of the basic operation amplifier of signal processing module in the present invention;
Fig. 7 is the circuit theory diagrams of the preamplifier of signal processing module in the present invention;
Fig. 8 is the circuit theory diagrams of the low pass filter of signal processing module in the present invention;
Fig. 9 is the circuit theory diagrams of the secondary amplification module of signal processing module in the present invention;
Figure 10 is the composition block diagram of power management module in the present invention;
Figure 11 is the circuit theory diagrams of the Voltage stabilizing module of power management module in the present invention
In figure
1:Pulse blood oxygen acquisition module 2:Signal processing module
3:The radio receiving transmitting module of power management module 4
5:Chip protection shell 6 dermal harvest contact zone
7:Skin and the simple view of internal capillary blood vessel
101:Red-light source 102:Infrared light supply
103:LED drive module 104:Photodetector
201:Current frequency converter 202:Current Voltage converter
203:Variable gain instrument amplifier 204:LFP low pass filters
205:Two-stage amplifier 206:Counter
207:ADC analog-to-digital conversion devices
Embodiment
A kind of wireless pulse blood oxygen transducer transceiver chip of the present invention is made in detail with reference to embodiment and accompanying drawing Describe in detail bright:
As shown in figure 1, wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including power management module, arteries and veins Fight blood oxygen acquisition module, signal processing module and radio receiving transmitting module.Power management module is connected with each module, is that each module is carried For the support of stable power supply;The output end of pulse blood oxygen acquisition module connects the input of signal processing module, signal transacting The output end of module connects the input of radio receiving transmitting module, and digitized signal is utilized RFID technique by radio receiving transmitting module, Reader is sent to by label, the signal received is passed to host computer by reader, and host computer is carried out after modulating signals into Analyzing and processing, draws the information of human pulse and blood oxygen saturation and shows corresponding numerical value over the display, if existing abnormal Then alarm is sent to user.
The power management module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that use 1.8 volts LVPS improves the endurance of chip to reduce chip power-consumption;Including Voltage stabilizing module, charging module and battery module, Power supply is provided for other modules to support;The output end of charging module connects the input of battery module, the output end of battery module Connect the input of Voltage stabilizing module.
The Voltage stabilizing module of described power management module uses low pressure difference linear voltage regulator LDO structures, including band-gap reference Voltage source, protection circuit, error amplifier, power tube and sampling resistor;The output end connection error of bandgap voltage reference is put The positive pole of big device, the intermediate ends of sampling resistor connect the negative pole of error amplifier, the output end connection power tube of error amplifier Grid, the source electrode connection power supply VCC of power tube, drain electrode connection output end, one end connection power supply VCC of protection circuit is another The grid of end connection power tube, one end connection ground GND of sampling resistor, other end connection output end.
The pulse blood oxygen acquisition module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including ripple A length of 660nm red light-emitting diode, wavelength is 940nm near infrared light emitting diode, photodetector and LED drivings Module.
The signal processing module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including electric current frequency Rate converter, Current Voltage modular converter, preamplifier, low pass filter, secondary amplification module, counter and analog-to-digital conversion Device;The output end of current frequency converter connects the input of Current Voltage modular converter, the output of Current Voltage modular converter The input of end connection preamplifier, the output end of preamplifier connects the input of low pass filter, low pass filter Output end connecting secondary amplification module input, the output end of secondary amplification module connects the input of analog-digital converter, The input of the output end linkage counter of analog-digital converter, and the input of connection radio receiving transmitting module, the output of counter The input of end connection radio receiving transmitting module.
The preamplifier of described signal processing module, it is characterised in that including three operational amplifiers, six accurate Resistance and a variable resistor, its yield value amplified can be adjusted by changing the resistance of variable resistor.
The radio receiving transmitting module of described wireless pulse blood oxygen transducer transceiver chip, it is characterised in that use RFID skills Art, it is possible to achieve to the wireless transmission of the data obtained, matching reader can receive gained signal, and by the letter received Number host computer is sent to, host computer can be analyzed signal, draw the vital sign informations such as the pulse and blood oxygen of human body.
As shown in Fig. 2 being the configuration schematic diagram of wireless pulse blood oxygen transducer transceiver chip of the present invention, its core is bag It is rolled in the chip of inside, including pulse blood oxygen acquisition module 1, signal processing module 2, power management module 3 and wireless receiving and dispatching mould Block 4, the acquisition zone 6 and shell 7 that whole device is contacted by skin is wrapped up, and the information collected is wirelessly issued into host computer, is carried out Next step processing, finally on machine display pulse and blood oxygen information.
Whole device is contacted by skin contact zone 6 with human body skin 7, and pulse is obtained using pulse blood oxygen acquisition module 1 With the information of blood oxygen, then by signal processing module 2, faint physiological signal is subjected to frequency conversion, preliminary amplification is filtered out and made an uproar Sound and interference information, secondary amplification count and digitized, host computer is sent by RFID.
As shown in figure 3, pulse blood oxygen acquisition module 1 includes red-light source 101, infrared light light source 102, LED drive module 103, and photodetector 104, detected using reflection pulse blood oxygen, i.e., light source and photodetector are located at the same of tissue Side, the light part that light source is sent is absorbed after tissue, and another part reflected light is received by a photoelectric detector; Two kinds of hemoglobins present in human body are very big in red spectral regions absorption difference, and absorb difference very near infrared spectrum It is small, so the blood of different blood oxygen saturations is relevant with two kinds of content of hemoglobin ratios to the degree of absorption of light.According to lambert Feux rouges and the volume pulsation wave (PPG) of infrared light that one Beer law analysis photo-detector is detected, you can calculate hemoglobin Concentration and blood oxygen saturation.
As shown in figure 4, signal processing module 2 includes current frequency converter, current-to-voltage convertor, variable gain instrument Amplifier, low pass filter and secondary amplification module, power management module 3 provide power supply for its modules and supported, by pulse The information that blood oxygen acquisition module 1 is collected, carries out frequency conversion, and photovoltaic conversion, one-level amplification filters out high-frequency signal and secondary put Greatly, to ensure that signal can be analyzed preferably, modulation /demodulation.
Wherein the basic structure of Current Voltage converter is as shown in figure 5, input current is by a resistance (high accuracy, warm Stability is good) its is produced a voltage, then by voltage by voltage follower (or amplifier), will input and export every Leave and, the voltage for making its load that electric current can not be influenceed to be produced on resistance.Then through a voltage follower (or amplifier) Output, and C1 filters out the interference of high-frequency signal;Its advantage is:Load does not influence transformational relation.
One of them basic operational amplifier is as shown in fig. 6, M1-M5 constitutes the first order of amplifier, and M6 and M7 constitute the The amplification of two grades of common sources, to obtain bigger gain, Rz and Cc as frequency compensation, compensation limit so that system is more stablized, M8- M11 and R1 is the temperature independent bias voltage of circuit with stable.
The instrument amplifier of one variable gain is as shown in fig. 7, comprises three amplifiers A1, A2 and A3 and 6 resistance R1- R6 and variable resistor Rw, circuit gain can change Rw resistance and change, to adapt to different amplification requirements.When pulse blood When the pulse wave signal collected is transmitted next by oxygen acquisition module 1, through overfrequency and voltage conversion, instrument amplifier is connected into Input, addition bias voltage once amplifies small-signal 20~30 times, in order to reach the operating point of subsequent treatment link.
One low-pass first order filter as shown in figure 8, can filter out by high-frequency signal, reduce noise and unnecessary The interference of signal.Instrument amplifier output connection low pass filter input, signal after filtering device by frequency higher than cut Only the signal of frequency is filtered out, and obtains low frequency signal.
Secondary amplification uses an in-phase amplifier with amplified signal, as shown in Figure 9;Including two sampling resistors and computing Amplifier;The output end of low pass filter connects the input of in-phase amplifier, because using the low power supplys of 1.8v, therefore in-phase amplifier Multiplication factor be set to twice, with pre- anti-distortion, you can with by the signal of input it is undistorted amplification twice.
It is as shown in Figure 10 the fundamental block diagram of power management module 3, including charging module, battery and Voltage stabilizing module.Wherein Voltage stabilizing module uses LDO linear voltage regulators, and its structure is as shown in figure 11.Voltage-stablizer can be with stabilized supply voltage, and can also produce needs The stable bias voltage wanted;Its structure includes bandgap voltage reference, error amplifier, protection circuit and feedback control loop;Wherein Protection circuit includes current foldback circuit and thermal-shutdown circuit, can be effectively protected power supply, prevent electric current excessive or temperature The too high damage caused to system.
One embodiment of the present of invention is described in detail above, but the content is only the preferable implementation of the present invention Example, it is impossible to be considered as the practical range for limiting the present invention;All equivalent changes made according to the present patent application scope and improvement Deng within the patent covering scope that all should still belong to the present invention.

Claims (7)

1. wireless pulse blood oxygen transducer transceiver chip, it is characterised in that including power management module, pulse blood oxygen collection mould Block, signal processing module and radio receiving transmitting module.Power management module is connected with each module, and stable power supply is provided for each module Support;The output end of pulse blood oxygen acquisition module connects the input of signal processing module, the output end of signal processing module The input of radio receiving transmitting module is connected, digitized signal is utilized RFID technique, sent by label by radio receiving transmitting module To reader, the signal received is passed to host computer by reader, and host computer is analyzed and processed after modulating signals into, drawn The information of human pulse and blood oxygen saturation simultaneously shows corresponding numerical value over the display, is sent if it there is exception to user Alarm.
2. the power management module of wireless pulse blood oxygen transducer transceiver chip as claimed in claim 1, it is characterised in that Use 1.8 volts of LVPSs to reduce chip power-consumption, improve the endurance of chip;Including Voltage stabilizing module, charging module and Battery module, provides power supply for other modules and supports;The output end of charging module connects the input of battery module, battery module Output end connect Voltage stabilizing module input.
3. the Voltage stabilizing module of power management module as claimed in claim 2 uses low pressure difference linear voltage regulator LDO structures, including Bandgap voltage reference, protection circuit, error amplifier, power tube and sampling resistor;The output end of bandgap voltage reference connects The positive pole of error amplifier is connect, the intermediate ends of sampling resistor connect the negative pole of error amplifier, and the output end of error amplifier connects Connect the grid of power tube, the source electrode connection power supply VCC of power tube, drain electrode connection output end, one end connection power supply of protection circuit VCC, the other end connects the grid of power tube, one end connection ground GND of sampling resistor, other end connection output end.
4. the pulse blood oxygen acquisition module of wireless pulse blood oxygen transducer transceiver chip as claimed in claim 1, its feature It is to include the red light-emitting diode that wavelength is 660nm, wavelength is 940nm near infrared light emitting diode, photodetection Device and LED drive module.
5. the signal processing module of wireless pulse blood oxygen transducer transceiver chip as claimed in claim 1, it is characterised in that Including current frequency converter, Current Voltage modular converter, preamplifier, low pass filter, secondary amplification module, counter And analog-digital converter;The output end of current frequency converter connects the input of Current Voltage modular converter, Current Voltage conversion The output end of module connects the input of preamplifier, and the output end of preamplifier connects the input of low pass filter, The input of the output end connecting secondary amplification module of low pass filter, the output end connection analog-digital converter of secondary amplification module Input, the input of the output end linkage counter of analog-digital converter, and connection radio receiving transmitting module input, count The output end of device connects the input of radio receiving transmitting module.
6. the preamplifier of signal processing module as claimed in claim 5, it is characterised in that including three operational amplifiers, Six precise resistances and a variable resistor, its yield value amplified can be adjusted by changing the resistance of variable resistor.
7. the radio receiving transmitting module of wireless pulse blood oxygen transducer transceiver chip as claimed in claim 1, it is characterised in that Using RFID technique, it is possible to achieve to the wireless transmission of the data obtained, matching reader can receive gained signal.
CN201710411148.8A 2017-05-31 2017-05-31 Wireless pulse blood oxygen transducer transceiver chip Pending CN107041754A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019157090A3 (en) * 2018-02-06 2020-04-16 Mckirdy, Sean System and method for providing fluidic performance characteristics to a diagnostic platform

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103750827A (en) * 2014-01-22 2014-04-30 杭州电子科技大学 Wearable physiological parameter collecting device based on WIFI communication
CN104382601A (en) * 2014-11-21 2015-03-04 天津大学 Blood oxygen pulse detection system based on RFID (radio frequency identification)
CN104490404A (en) * 2014-12-12 2015-04-08 天津大学 Cordless pulse oximeter

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103750827A (en) * 2014-01-22 2014-04-30 杭州电子科技大学 Wearable physiological parameter collecting device based on WIFI communication
CN104382601A (en) * 2014-11-21 2015-03-04 天津大学 Blood oxygen pulse detection system based on RFID (radio frequency identification)
CN104490404A (en) * 2014-12-12 2015-04-08 天津大学 Cordless pulse oximeter

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019157090A3 (en) * 2018-02-06 2020-04-16 Mckirdy, Sean System and method for providing fluidic performance characteristics to a diagnostic platform

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