CN104382601A - Blood oxygen pulse detection system based on RFID (radio frequency identification) - Google Patents
Blood oxygen pulse detection system based on RFID (radio frequency identification) Download PDFInfo
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- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
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Abstract
The invention discloses a blood oxygen pulse detection system based on RFID (radio frequency identification), and relates to the blood oxygen pulse detection system field. The blood oxygen pulse detection system based on the RFID comprises a blood oxygen pulse detection processing module, a radio frequency tag, a reader, a control module and an upper computer, wherein the blood oxygen pulse detection processing module comprises a blood oxygen pulse sensor, a signal processing circuit and a microprocessor, the blood oxygen pulse sensor uses a reflection type detection method, the radio frequency tag receives a control command sent by the reader, and sends digital baseband information processed by the microprocessor to the reader in space electromagnetic wave mode, the reader is communicated with the radio frequency tag through space electromagnetic waves, and the reader sends the control command to the radio frequency tag and receives blood oxygen pulse information sent back by the radio frequency tag. The blood oxygen pulse detection system based on the RFID can send vital sign information obtained by the blood oxygen pulse sensor out through the radio frequency tag, can achieve real time detection of middle and long distances, is good in safety, long in life and strong in interference resisting ability, and can be embedded into other wearable devices.
Description
Technical field
The present invention relates to blood oxygen pulse detection system field, particularly relate to a kind of blood oxygen pulse detection system based on RFID (RF identification).
Background technology
Along with the arrival of large data age, the informationization of medical industry also welcomes oneself " large data age ", i.e. wearable intelligent medical treatment.Intelligent medical treatment utilizes advanced technology of Internet of things, realizes patient and medical personnel, interaction between medical institutions and armarium, and progressively reaches information-based.Intelligent medical treatment is made up of regional health system, wisdom hospital system and family health care system three part.Along with the develop rapidly of information technology especially microelectric technique, interaction technique, the information processing technology and communication technology, wearable intelligent medical treatment has great significance to the aging present situation solving Chinese people mouth structure.
In intelligent medical treatment system, blood oxygen pulse signal is an important parameter characterizing health degree.Blood oxygen saturation characterizes the oxygen content of blood of human body, and effectively can reflect the physiological status of human recycle system and respiratory system, be one of vital sign index of human metabolism, is also the important physiological parameter of human respiratory and blood circulation pathological diagnosis.The clinical manifestation of a lot of disease all can cause the blood oxygen saturation in human body linked groups and organ to change, thus cause anoxia, even threat to life, so detection pulse and blood oxygen saturation play positive effect in condition-inference and health supervision safely and effectively.
Traditional measurement method of blood oxygen saturation needs to carry out blood sampling to patient and detects, and belongs to and has wound detection method, and except bringing the sense of discomfort of pain to patient, operating lack of standardization also may causing infects, and can not obtain testing result continuously, in real time.In addition, traditional method needs medical personnel in person to operate, and excessively takies the time and efforts of medical personnel, thus causes medical resource nervous.
Along with deepening continuously of studying pulse and oxygen saturation measurement, and the various low-power consumption such as bluetooth, ZigBee, WIFI, short-distance wireless communication technology development, utilize body surface sensor acquisition monitored signal, and by the way by data information transfer on terminal unit, thus substitute traditional complicated electrical wiring, offer convenience and better comfort level to patient.
But bluetooth, ZigBee and WiFi technology exist some drawbacks, such as: all need power supply support, size and the motility of instrument and equipment is thus limited; Secondly, the cost of above-mentioned technology is higher, with current technology of Internet of things poor compatibility.
Summary of the invention
The invention provides a kind of blood oxygen pulse detection system based on RFID, this system has the advantages such as easily worn, low-power consumption and capacity of resisting disturbance are strong, can realize the noinvasive of blood oxygen pulse information, real-time and medium and long distance monitoring, described below:
A kind of blood oxygen pulse detection system based on RFID, comprise: the detection of blood oxygen pulse processing module, radio-frequency (RF) tag, reader, control module and host computer, described blood oxygen pulse detection processing module comprises: blood oxygen pulse sensor, signal processing circuit and microprocessor, wherein, described blood oxygen pulse sensor adopts reflective detection mode;
Described radio-frequency (RF) tag receives the control command that described reader sends, and the digital baseband information described microprocessor processes crossed sends to described reader by the mode of spatial electromagnetic ripple; Described reader is communicated with described radio-frequency (RF) tag by spatial electromagnetic ripple, and described reader to described radio-frequency (RF) tag transmitting control commands, and receives the blood oxygen pulse information that described radio-frequency (RF) tag sends it back.
Described blood oxygen pulse sensor comprises: double-wavelength light source and photodetector, the light of described double-wavelength light source red-emitting and infrared light two kinds of different wave lengths under described microprocessor-based control, light is by after skin histology, be reflected back the optical signal carrying blood oxygen pulse information, the optical signal received is converted to the signal of telecommunication by described photodetector, and transfers to described signal processing circuit.
Described signal processing circuit comprises: amplifying circuit, demultiplexing circuit, red signal light circuit, infrared signal circuit and analog-digital converter,
The signal of telecommunication be aliasing in together carries out amplifying by described amplifying circuit, filtering, then described demultiplexing circuit is isolated into two path signal, after described red signal light circuit and described infrared signal processing of circuit, described analog-digital converter is transformed to digital signal.
Described radio-frequency (RF) tag comprises: antenna, rf analog front-end and digital baseband three parts; Wherein, described rf analog front-end comprises: for filtering radiofrequency signal noise and signal amplifying signal amplification module; For radiofrequency signal mixing being become the frequency mixing module of fixed intermediate frequency; For to the filtration module of signalling mirror as filtering; For signal receiving being become the demodulation module of order data; For label digital baseband return data being carried out the modulation module of orthogonal modulation; For digital signal being converted to the D/A converter module of analogue signal; For carrying out the rectification module of shaping pulse to signal; For signal in orthogonal mixing being produced the frequency mixing module of radiofrequency signal.
The beneficial effect of technical scheme provided by the invention is:
1, the Real-Time Monitoring achieving vital sign information combines with RFID technique.The vital sign information that blood oxygen pulse sensor obtains is sent by radio-frequency (RF) tag, the real-time detection of medium and long distance can be realized;
2, wearable blood oxygen pulse label integrated level provided by the invention is high, and safety is good, and the life-span is long, and capacity of resisting disturbance is strong, can embed in other wearable devices;
3, adopt reflective detection mode, be easier to tags detected to be affixed on human tissue surface, realize noinvasive, real-time blood oxygen pulse detects, avoid the injury that wound formula detection method is brought to patient, for patient provides better medical treatment to experience;
4, the human life characteristic information of blood oxygen pulse sensor measurement can be presented in PC terminal by host computer display routine in real time.By detecting the analysis of data to entire patient, the assurance of medical personnel to conditions of patients is more deep, directly perceived.Operation system setting numerical value alarm, when pulse and blood oxygen saturation will give the alarm lower than during a certain setting numerical value, thus effectively reduces the working strength of medical personnel.
To sum up, this blood oxygen pulse detection system has the advantages such as easily worn, low-power consumption and capacity of resisting disturbance are strong, can realize the noinvasive of blood oxygen pulse information, real-time and medium and long distance monitoring.The blood oxygen sensor-based system that the present invention proposes can be applicable to postoperative tracing observation in medical monitoring arts, neonatal care, community medicine and family health care.Due to blood oxygen pulse detection system provided by the invention have that cost is low, capacity of resisting disturbance is strong, can noinvasive, Real-Time Monitoring, thus to promotion community medicine, tele-medicine, the present situation solving China's medical resource anxiety is significant.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of the blood oxygen pulse detection system based on RFID;
Fig. 2 is the workflow diagram of reader;
Fig. 3 is the structure chart of radio-frequency (RF) tag;
Fig. 4 is the structural representation of reflective blood oxygen pulse detection processing module.
In accompanying drawing, the list of parts representated by each label is as follows:
1: blood oxygen pulse detection processing module; 2: radio-frequency (RF) tag;
3: reader; 4: control module;
5: host computer; 6: skin histology;
7: blood;
11: blood oxygen pulse sensor; 12: signal processing circuit;
13: microprocessor; 111: double-wavelength light source;
112: photodetector; 121: amplifying circuit;
122: demultiplexing circuit; 123: red signal light circuit;
124: infrared signal circuit; 125: analog-digital converter;
21: antenna; 22: rf analog front-end;
23: digital baseband;
221: for filtering radiofrequency signal noise and signal amplifying signal amplification module;
222: for radiofrequency signal mixing being become the frequency mixing module of fixed intermediate frequency;
223: for the filtration module of signalling mirror as filtering;
224: for signal receiving being become the demodulation module of order data;
225: for label digital baseband return data being carried out the modulation module of orthogonal modulation;
226: for digital signal being converted to the D/A converter module of analogue signal;
227: for carrying out the rectification module of shaping pulse to signal;
228: for signal in orthogonal mixing being produced the frequency mixing module of radiofrequency signal.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly, below embodiment of the present invention is described further in detail.
Embodiment 1
See Fig. 1, the blood oxygen pulse detection system based on RFID that the present invention proposes comprises: the detection of blood oxygen pulse processing module 1, radio-frequency (RF) tag 2, reader 3, control module 4 and host computer 5.Wherein, blood oxygen pulse detection processing module 1: comprise blood oxygen pulse sensor 11, signal processing circuit 12 and microprocessor 13.
See Fig. 4, blood oxygen pulse sensor 11 comprises: double-wavelength light source 111 and photodetector 112, and double-wavelength light source 111 and photodetector 112 are in the same side.The light of double-wavelength light source 111 red-emitting and infrared light two kinds of different wave lengths under the control of microprocessor 13, light is by after skin histology 6, the optical signal carrying blood oxygen pulse information is reflected back through blood 7, the optical signal received is converted to the signal of telecommunication by photodetector 112, and sends into signal processing circuit 12 and carry out post processing.
See Fig. 4, signal processing circuit 12 comprises: amplifying circuit 121, demultiplexing circuit 122, red signal light circuit 123, infrared signal circuit 124 and analog-digital converter 125, the signal of telecommunication be aliasing in together carries out amplifying by amplifying circuit 121, filtering, then demultiplexing circuit 122 is isolated into two path signal, after red signal light circuit 123 and infrared signal circuit 124 process, analog-digital converter 125 is transformed to digital signal.
Microprocessor 13 is cores of whole blood oxygen pulse monitoring system, and its Main Function is each electronic circuit controlling blood oxygen pulse detection processing module 1, and the blood oxygen pulse information of processing signals treatment circuit 12 output further.
Radio-frequency (RF) tag 2 receives the control command that reader 3 sends, and the digital baseband information processed through microprocessor 13 is sent to reader 3 by the form of spatial electromagnetic ripple.
Reader 3 is communicated with radio-frequency (RF) tag 2 by spatial electromagnetic ripple, and it is to radio-frequency (RF) tag 2 transmitting control commands, and the blood oxygen pulse information that received RF label 2 sends it back.
Host computer 5 for showing and analyze the testing result of blood oxygen pulse monitoring system, and carries out alarm according to testing result.
Wherein, blood oxygen pulse sensor 11 provided by the invention adopts reflective detection mode, thus avoids the limitation of transmission-type structure, is convenient to the realization of wearable device.Therefore, any position of human body surface can be placed on, such as: embed the article next to the skin such as wrist-watch, ring and carry out the measurement of blood oxygen pulse.
Because the integrated level of microprocessor 13 is very high, can be the resource that user provides a large amount of.Therefore, effectively can reduce design difficulty and the system bulk of peripheral circuit, be conducive to the realization of Wearable device.
Embodiment 2
Containing HbO2 Oxyhemoglobin (HbO in blood
2) and reduced hemoglobin (Hb).Oxygen molecule combines with the reduced hemoglobin (Hb) in blood, just defines HbO2 Oxyhemoglobin (HbO
2).After HbO2 Oxyhemoglobin arrives blood capillary by arterial blood, release oxygen molecule, for organizing metabolism to provide nutrient, reverts to reduced hemoglobin simultaneously.Blood oxygen saturation is the important parameter of oxygen content in reflection blood, is whether extremely to weigh body metabolism, the important vital sign index whether hemodynamics is disorderly.Blood oxygen saturation is defined as the percentage ratio that HbO2 Oxyhemoglobin concentration accounts for total hemoglobin concentration, that is:
In formula, C
hbO2represent the concentration of HbO2 Oxyhemoglobin, C
hbrepresent the concentration of reduced hemoglobin, both sums are total hemoglobin concentration.
According to Lambert-beer's law (Lamber-Beer), non-pulsating composition (as skin, muscle, skeleton, venous blood etc.) and ripple component (as arterial blood) can be divided into, also referred to as DC component and AC compounent by the light of tissue and blood vessel.Therefore, the rate of change of light intensity in tissue can be expressed as:
W＝I
AC/I
DC(2)
In formula, I
aCand I
dCrepresent the AC compounent that blood reflected light is strong and DC component respectively.According to reference beam method, the light that HONGGUANG and infrared light supply send has different reflective light intensities, and the ratio of both rates of change is
Wherein, W
rrepresent HONGGUANG light intensity rate of change in blood, W
iRrepresent infrared light light intensity rate of change in blood,
represent the AC compounent of reflection to red light light intensity,
represent the DC component of reflection to red light light intensity,
represent the AC compounent of infrared light reflection light intensity,
represent the DC component of infrared light reflection light intensity.
Through theoretical derivation, the relation of blood oxygen saturation and light intensity rate of change can be obtained
Wherein,
with
be constant.These constants obtain by time domain or frequency domain spectra analytic process.After (3) formula is substituted into (4) formula, blood oxygen saturation SpO
2can abbreviation be
SpO
2＝k
1-k
2*A (5)
Wherein, k
1, k
2for constant, acquisition can be measured by experiment.A is the ratio of HONGGUANG light intensity and infrared light light intensity rate of change in blood.
As shown in Figure 1, the blood oxygen pulse detection system based on RFID provided by the invention mainly comprises: blood oxygen pulse detection processing module 1, radio-frequency (RF) tag 2, reader 3, control module 4 and host computer 5 (PC) five parts.During the work of blood oxygen pulse detection system, first host computer 5 sends the instruction of measuring blood oxygen pulse to reader 3 by control module 4, reader 3 selects the radio-frequency (RF) tag 2 of pretest, and the faradic current that selected radio-frequency (RF) tag 2 is produced by external electromagnetic field obtains energy, thus is activated.Then reader 3 sends the instruction of reading blood oxygen pulse information to radio-frequency (RF) tag 2, and the data message that blood oxygen pulse detection processing module 1 detects is passed to reader 3 by RF-wise by radio-frequency (RF) tag 2.Reader 3 sends data message to host computer 5 by control module 4, and shows in its terminal, thus completes the collection of blood oxygen pulse information, transmission and display.
Be illustrated in figure 2 the workflow of reader 3.Host computer 5 (PC) is first driven by hardware bottom layer and the microcontroller of interface layer function to control module 4 initializes, and comprising: pin configuration, clock configuration, UART (UART Universal Asynchronous Receiver Transmitter) setting, SPI (Serial Peripheral Interface (SPI)) setting, external interrupt setting, intervalometer and enumerator are arranged.Then by protocol layer function, Initialize installation is carried out to reader 3, comprise the code modulation mode of reader 3, operating frequency, transmitting power, the transfer rate of receptor gain and label, code modulation mode and preamble format etc.Initialize successfully in control module 4 and reader 3, system application layer is tested oneself, and judges whether host computer 5 sends order.If not, then continue to test oneself; If it is the corresponding command is performed.When reader 3 receives the Call Select Tag order of control module 4 transmission, reader 3 sends Select order to radio-frequency (RF) tag 2, selects and activates label.When reader 3 receives the Call Read From Tag order of control module 4 transmission, reader 3 sends Read order to radio-frequency (RF) tag 2, and reads the blood oxygen pulse information in radio-frequency (RF) tag 2 digital baseband.
Figure 3 shows that the structure chart of radio-frequency (RF) tag 2.This radio-frequency (RF) tag 2 comprises: antenna 21, rf analog front-end 22 and digital baseband 23 3 parts.Rf analog front-end 22 comprises with lower module: for filtering radiofrequency signal noise and signal amplifying signal amplification module 221; For radiofrequency signal mixing being become the frequency mixing module 222 of fixed intermediate frequency; For to the filtration module 223 of signalling mirror as filtering; For signal receiving being become the demodulation module 224 of order data; For label digital baseband return data being carried out the modulation module 225 of orthogonal modulation; For digital signal being converted to the D/A converter module 226 of analogue signal; For carrying out the rectification module 227 of shaping pulse to signal; For signal in orthogonal mixing being produced the frequency mixing module 228 of radiofrequency signal.
The communication process of radio-frequency (RF) tag 2 Received signal strength is as follows: rf analog front-end 22 receives the radio frequency reading order that reader 3 sends, amplify through noise filtering and signal, this radiofrequency signal mixing is become fixed intermediate frequency, again through process such as mirror image filtering and signal amplifications, finally be demodulated to order data, send into digital baseband and carry out reading process, and control the digital baseband that blood oxygen pulse information is imported into radio-frequency (RF) tag 2 by blood oxygen pulse detection processing module 1.
Be illustrated in figure 4 the schematic diagram of blood oxygen pulse detection processing module 1.This blood oxygen pulse detection processing module 1 comprises: blood oxygen pulse detector 11, signal processing circuit 12 and microprocessor 13.Blood oxygen pulse detector 11 is made up of double-wavelength light source 111 (red-light LED, infrared light LED) and photodetector 112, the skin surface of detected patient is placed or be fitted in this blood oxygen pulse detector 11, and photodetector 112 and double-wavelength light source 111 are all placed in the same side of detection site.During the work of blood oxygen pulse detection system, radio-frequency (RF) tag 2 activates, and the square-wave signal of certain frequency is exported by controlling microprocessor 13, this signal drives HONGGUANG and infrared light LED luminescence, HONGGUANG and infrared light skin histology 6, the optical signal be reflected back toward through blood 7 is received by photodetector 112, and converts it into current signal and input follow-up signal processing circuit 12.Signal processing circuit 12 comprises: amplifying circuit 121, demultiplexing circuit 122, red signal light circuit 123, infrared signal circuit 124 and analog-digital converter 125.Be input to the signal of the current signal aliasing of signal processing circuit 12 HONGGUANG and infrared light two kinds of wavelength, this signal improves signal to noise ratio by amplification, filtering with being separated, finally by analog-digital converter 125, the analogue signal of two kinds of different voltages is converted to digital signal, then stored in the memorizer of microprocessor 13.After radio-frequency (RF) tag 2 is activated, the blood oxygen pulse information in the memorizer of microprocessor 13 is sent to the digital baseband part of radio-frequency (RF) tag 2.As shown in Figure 3, this data message finally produces radiofrequency signal, sends it back reader 3 by antenna 21 after carrying out the process such as orthogonal modulation, digital-to-analogue conversion, shaping pulse, quadrature downconvert and amplification through rf analog front-end 22.After DTD, radio-frequency (RF) tag 2 enters resting state, waits for selected activation again.After reader 3 receives the blood oxygen pulse information of sending from radio-frequency (RF) tag 2, effective information is delivered to host computer 5 after demodulation code and carry out respective handling.Host computer 5 applies VC++ programming software exploitation detection system DP display processor, and digital signal calculates through respective algorithms, obtains HONGGUANG and infrared light rate of change in blood, i.e. W
rand W
iR, get A=W
r/ W
iR(5) formula of substitution, can obtain blood oxygen saturation SpO
2.
Display interface is by SpO
2detect numerical value and present to medical personnel intuitively, and give the alarm lower than during a certain appointment numerical value in blood oxygen saturation.Meanwhile, host computer 5 can store the blood oxygen pulse information of whole detection period and analyze, medical personnel analyse in depth by selecting the blood oxygen pulse data message of patient in a certain period, provide reference for understanding conditions of patients development and formulating rational therapeutic scheme.
The embodiment of the present invention is to the model of each device except doing specified otherwise, and the model of other devices does not limit, as long as can complete the device of above-mentioned functions.
It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the invention described above embodiment sequence number, just to describing, does not represent the quality of embodiment.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. the blood oxygen pulse detection system based on RFID, comprise: the detection of blood oxygen pulse processing module, radio-frequency (RF) tag, reader, control module and host computer, it is characterized in that, described blood oxygen pulse detection processing module comprises: blood oxygen pulse sensor, signal processing circuit and microprocessor, wherein, described blood oxygen pulse sensor adopts reflective detection mode
Described radio-frequency (RF) tag receives the control command that described reader sends, and the digital baseband information described microprocessor processes crossed sends to described reader by the form of spatial electromagnetic ripple; Described reader is communicated with described radio-frequency (RF) tag by spatial electromagnetic ripple, and described reader to described radio-frequency (RF) tag transmitting control commands, and receives the blood oxygen pulse information that described radio-frequency (RF) tag sends it back.
2. a kind of blood oxygen pulse detection system based on RFID according to claim 1, it is characterized in that, described blood oxygen pulse sensor comprises: double-wavelength light source and photodetector,
The light of described double-wavelength light source red-emitting and infrared light two kinds of different wave lengths under described microprocessor-based control, light is by after skin histology, be reflected back the optical signal carrying blood oxygen pulse information, the optical signal received is converted to the signal of telecommunication by described photodetector, and transfers to described signal processing circuit.
3. a kind of blood oxygen pulse detection system based on RFID according to claim 1 and 2, it is characterized in that, described signal processing circuit comprises: amplifying circuit, demultiplexing circuit, red signal light circuit, infrared signal circuit and analog-digital converter,
The signal of telecommunication be aliasing in together carries out amplifying by described amplifying circuit, filtering, then described demultiplexing circuit is isolated into two path signal, after described red signal light circuit and described infrared signal processing of circuit, described analog-digital converter is transformed to digital signal.
4. a kind of blood oxygen pulse detection system based on RFID according to claim 1, it is characterized in that, described radio-frequency (RF) tag comprises: antenna, rf analog front-end and digital baseband three parts,
Wherein, described rf analog front-end comprises: for filtering radiofrequency signal noise and signal amplifying signal amplification module; For radiofrequency signal mixing being become the frequency mixing module of fixed intermediate frequency; For to the filtration module of signalling mirror as filtering; For signal receiving being become the demodulation module of order data; For label digital baseband return data being carried out the modulation module of orthogonal modulation; For digital signal being converted to the D/A converter module of analogue signal; For carrying out the rectification module of shaping pulse to signal; For signal in orthogonal mixing being produced the frequency mixing module of radiofrequency signal.
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Application publication date: 20150304 |