CN107029122B8 - 一种治疗高血压的药物组合物及其制备方法、制剂与应用 - Google Patents

一种治疗高血压的药物组合物及其制备方法、制剂与应用 Download PDF

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CN107029122B8
CN107029122B8 CN201710156838.3A CN201710156838A CN107029122B8 CN 107029122 B8 CN107029122 B8 CN 107029122B8 CN 201710156838 A CN201710156838 A CN 201710156838A CN 107029122 B8 CN107029122 B8 CN 107029122B8
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treating hypertension
preparation
parts
application
pharmaceutical composition
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CN107029122A (zh
CN107029122B (zh
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杨本雷
杨舒雅
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Chuxiong Yi Autonomous Prefecture Yi Medicine Research Institute
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Chuxiong Yi Autonomous Prefecture Yi Medicine Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

本发明公开了一种治疗高血压的药物组合物及其制备方法、制剂和应用。所述的治疗高血压的药物组合物由原料重量份的天麻100~300份、菊花50~200份、石决明100~200份、罗布麻50~150份、干地黄40~100份组成,经前处理、提取和后处理步骤制备得到。制剂为所述的治疗高血压的药物组合物中加入药学上可接受的辅料制备的片剂、散剂、胶囊剂、颗粒剂和丸剂。应用为所述的治疗高血压的药物组合物在制备治疗高血压药物中的应用。本发明诸药联合,协同作用,共奏滋肾养肝,平肝熄风之功,有显著的降压作用,用于高血压的治疗。
CN201710156838.3A 2017-03-16 2017-03-16 一种治疗高血压的药物组合物及其制备方法、制剂与应用 Active CN107029122B8 (zh)

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CN107029122B CN107029122B (zh) 2018-05-01
CN107029122B8 true CN107029122B8 (zh) 2024-06-11

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111773325A (zh) * 2020-07-31 2020-10-16 王广印 一种治疗高血压的药物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973816A (zh) * 2012-12-06 2013-03-20 常熟富士莱医药化工有限公司 一种治疗高血压的医药制剂
CN103417856A (zh) * 2013-08-28 2013-12-04 张鹏 一种治疗高血压的中药组合物
CN103961566A (zh) * 2014-05-27 2014-08-06 赵红侠 一种治疗高血压的药物及其制备方法
CN105194353A (zh) * 2015-11-10 2015-12-30 叶建斌 一种治疗高血压的中药口服液及制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102973816A (zh) * 2012-12-06 2013-03-20 常熟富士莱医药化工有限公司 一种治疗高血压的医药制剂
CN103417856A (zh) * 2013-08-28 2013-12-04 张鹏 一种治疗高血压的中药组合物
CN103961566A (zh) * 2014-05-27 2014-08-06 赵红侠 一种治疗高血压的药物及其制备方法
CN105194353A (zh) * 2015-11-10 2015-12-30 叶建斌 一种治疗高血压的中药口服液及制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"平肝活血法与平肝法治疗高血压病的疗效观察";付美琴等;《四川中医》;20021015;第20卷(第10期);第33-34页 *
"高血压病的中医药疗法概况";马惠英;《湖南中医杂志》;20060725;第22卷(第4期);第94-96页 *

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Effective date of registration: 20220402

Address after: 675000 No. 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

Patentee after: Chuxiong Yi Autonomous Prefecture Yi medicine Research Institute

Address before: 675000 Room 502, unit 2, building 5, 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

Patentee before: Yang Benlei

TR01 Transfer of patent right
CI03 Correction of invention patent

Correction item: Patentee|Address

Correct: Chuxiong Yi Autonomous Prefecture Yi Ethnic Medicine Research Institute|675000 No. 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

False: Yang Benlei|675000 Room 502, unit 2, building 5, 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

Number: 18-01

Page: The title page

Volume: 34

Correction item: Patentee|Address

Correct: Chuxiong Yi Autonomous Prefecture Yi Ethnic Medicine Research Institute|675000 No. 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

False: Yang Benlei|675000 Room 502, unit 2, building 5, 327 Lucheng West Road, Chuxiong City, Chuxiong Yi Autonomous Prefecture, Yunnan Province

Number: 18-01

Volume: 34

CI03 Correction of invention patent
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