CN107029105A - 治疗破伤风的药物 - Google Patents

治疗破伤风的药物 Download PDF

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CN107029105A
CN107029105A CN201710238692.7A CN201710238692A CN107029105A CN 107029105 A CN107029105 A CN 107029105A CN 201710238692 A CN201710238692 A CN 201710238692A CN 107029105 A CN107029105 A CN 107029105A
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赵婉治
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Abstract

本发明提供一种治疗破伤风的药物，由下述重量份的原料制得：玉竹草10‑30克、五爪风10‑30克、车前草10‑30克、蒲公英10‑30‑克、金银花10‑30克、当归10‑30克、败酱草10‑30克、连翘10‑20克、僵蚕8‑12克、栀子8‑12克、黄芪8‑15克、生地8‑15克、白芍15‑25克、甘草5‑10克、蜈蚣5‑15克、田鸡黄10‑20克。本发明是一种能迅速消灭破伤风杆菌的药物，对于治疗破伤风，具有见效快、效果好的独特优点。

Description

治疗破伤风的药物
技术领域
本发明涉及一种治疗破伤风的药物，属于中药技术领域。
背景技术
破伤风是一种由破伤风杆菌经伤口浸入人机体而引起的急性特异性感染疾病。本病是风毒自创伤口而入，袭于肌腠筋脉，内传脏腑，筋脉拘挛，产生大量外毒素而作用于中枢神经系统。其症发前一般表现为乏力、多汗、头痛、嚼肌酸胀、烦躁、或伤口有紧张牵拉感觉。多是由头面开始，扩展到肌体和四肢。临床表现为牙关紧闭、语言不清、张口困难、颈项强直、面呈苦笑、角弓反张、屈肘、半握拳、屈膝等。如稍有异物刺激，皆能引起全身性、阵发性肌肉痉挛和抽搐，以致营卫失调和肌腠经脉、筋脉肌肉痉挛，有的还会出现发热、头痛、畏寒等症状。严重者可因身体衰竭，窒息或并发肺炎而危及生命。目前治疗破伤风的药物以西药为主，这些药物价格高，副作用大，治疗效果不能令人满意。
发明内容
本发明要解决的技术问题是：提供一种治疗破伤风的药物，具有价格便宜，治疗效果好，毒副作用小的优点。
为解决上述问题，本发明采用以下技术方案：
治疗破伤风的药物，由下述重量份的原料制得：玉竹草10-30克、五爪风10-30克、车前草10-30克、蒲公英10-30-克、金银花10-30克、当归10-30克、败酱草10-30克、连翘10-20克、僵蚕8-12克、栀子8-12克、黄芪8-15克、生地8-15克、白芍15-25克、甘草5-10克、蜈蚣5-15克、田鸡黄10-20克。
作为优选的这里给出第一个具体的配方，所述原料的重量份为：玉竹草30克、五爪风30克、车前草30克、蒲公英10克、金银花10克、当归10克、败酱草10克、连翘15克、僵蚕10克、栀子10克、黄芪10克、生地10克、白芍20克、甘草5克、蜈蚣10克、田鸡黄10-20克。
作为优选的这里给出第二个具体的配方，所述原料的重量份为：玉竹草10克、五爪风10克、车前草10克、蒲公英30克、金银花30克、当归30克、败酱草30克、连翘20克、僵蚕12克、栀子12克、黄芪8克、生地8克、白芍15克、甘草8克、蜈蚣15克、田鸡黄10-20克。
作为优选的这里给出第三个具体的配方，所述原料的重量份为：玉竹草20克、五爪风20克、车前草20克、蒲公英20克、金银花20克、当归20克、败酱草20克、连翘10克、僵蚕8克、栀子8克、黄芪15克、生地15克、白芍25克、甘草10克、蜈蚣5克、田鸡黄10-20克。
本发明还提供上述药物的制备方法，其步骤如下为：(1)将所具备的原料洗净，放进砂锅里，加入5倍的清水浸泡20分钟，然后用文火慢慢煎40-50分钟，滤出药渣即可，(2)再将田鸡黄放入锅中加入加500毫升清水，用猛火煮10分钟后，即可得到该药物。
该药物的使用方法为：将药物(1)一日分早、中、晚三次每次服用200-300毫升，再将温药物(2)给伤口冲洗，每天1剂，使用3-7天，即可痊愈。
本发明的有益效果是：本发明的原料为常用中草药，来源广泛，价格便宜；药物配方科学合理，具有宣通经络，驱风、镇痛、解毒的功效，是治疗破伤风的良药。经30例患者治疗，用药3-7天，其中治愈28例，有效率为93％以上，且无患者出现不良反应，说明本发明的药物见效快、疗效好。
具体实施方式
以下通过实施例进一步说明本发明，但本发明不限于这些实施例。
实施例1
治疗破伤风的药物，由下述重量份的原料制得：玉竹草30克、五爪风30克、车前草30克、蒲公英10克、金银花10克、当归10克、败酱草10克、连翘15克、僵蚕10克、栀子10克、黄芪10克、生地10克、白芍20克、甘草5克、蜈蚣10克、田鸡黄10-20克。
药物的制备方法为：(1)将所具备的原料洗净，放进砂锅里，加入5倍的清水浸泡20分钟，然后用文火慢慢煎40-50分钟，滤出药渣即可，(2)再将田鸡黄放入锅中加入加500毫升清水，用猛火煮10分钟后，即可得到该药物。
实施例2
治疗破伤风的药物，由下述重量份的原料制得：玉竹草10克、五爪风10克、车前草10克、蒲公英30克、金银花30克、当归30克、败酱草30克、连翘20克、僵蚕12克、栀子12克、黄芪8克、生地8克、白芍15克、甘草8克、蜈蚣15克、田鸡黄10-20克。
药物的制备方法为：(1)将所具备的原料洗净，放进砂锅里，加入5倍的清水浸泡20分钟，然后用文火慢慢煎40-50分钟，滤出药渣即可，(2)再将田鸡黄放入锅中加入加500毫升清水，用猛火煮10分钟后，即可得到该药物。
治疗破伤风的药物，由下述重量份的原料制得：玉竹草20克、五爪风20克、车前草20克、蒲公英20克、金银花20克、当归20克、败酱草20克、连翘10克、僵蚕8克、栀子8克、黄芪15克、生地15克、白芍25克、甘草10克、蜈蚣5克、田鸡黄10-20克。
药物的制备方法为：(1)将所具备的原料洗净，放进砂锅里，加入5倍的清水浸泡20分钟，然后用文火慢慢煎40-50分钟，滤出药渣即可，(2)再将田鸡黄放入锅中加入加500毫升清水，用猛火煮10分钟后，即可得到该药物。
毒性试验
试验药品以本发明实施例1中的药物。实验动物TCR种小白鼠，体重20-30克，雌雄各半，共40只。使用方法是，禁食15小时后，按10克/千克，给小白鼠灌胃4个月，长期毒性试验结果显示，小白鼠体重、肝功能、肾功能、血象等与对照组无明显差异，表明该药物的安全性大属于无毒级别。
典型病例
病例1，曾xx，男，21岁，农民，因劈柴时不慎左足髁部被斧子砍伤，流血不止，到村卫生所缝合止血并上药。两天后觉面部不适，恶心，呕吐。第三天上午病情加重，乃四肢抽搐，逐送医院治疗，诊断为破伤风。用实施例1制得的药物治疗，服药三剂后，病情变化明显，患者神志清楚，语言正常，抽搐及项强等症消失，此后再服四剂，患者一切症状消失，
痊愈。病例2，蒋xx，男，42岁，被拖拉机撞伤左手虎口，当时未加处理，三天后，突然感觉面部肌肉酸痛，继而出现苦笑面容，肌肉痉挛抽搐，日十余次。经中西医会诊，诊断为破伤风。用实施例2制得的药物治疗，连服七日痊愈。

Claims (5)

1.治疗破伤风的药物，其特征在于，由下述重量份的原料制得：玉竹草10-30克、五爪风10-30克、车前草10-30克、蒲公英10-30-克、金银花10-30克、当归10-30克、败酱草10-30克、连翘10-20克、僵蚕8-12克、栀子8-12黄芪8-15克、生地8-15克、白芍15-25克、甘草5-10克、蜈蚣5-15克、田鸡黄10-20克。
2.根据权利要求1所述的药物，其特征在于，所述原料重量份为：玉竹草30克、五爪风30克、车前草30克、蒲公英10克、金银花10克、当归10克、败酱草10克、连翘15克、僵蚕10克、栀子10克、黄芪10克、生地10克、白芍20克、甘草5克、蜈蚣10克、田鸡黄10-20克。
3.根据权利要求1所述的药物，其特征在于，所述原料重量份为：玉竹草10克、五爪风10克、车前草10克、蒲公英30克、金银花30克、当归30克、败酱草30克、连翘20克、僵蚕12克、栀子12克、黄芪8克、生地8克、白芍15克、甘草8克、蜈蚣15克、田鸡黄10-20克。
4.根据权利要求1所述的药物，其特征在于，所述原料重量份为：玉竹草20克、五爪风20克、车前草20克、蒲公英20克、金银花20克、当归20克、败酱草20克、连翘10克、僵蚕8克、栀子8克、黄芪15克、生地15克、白芍25克、甘草10克、蜈蚣5克、田鸡黄10-20克。
5.根据权利要求1～4中任一项所述的药物，其特征在于，药物的制备方法为：(1)将所具备的原料洗净，放进砂锅里，加入5倍的清水浸泡20分钟，然后用文火慢慢煎40-50分钟，滤出药渣即可，(2)再将田鸡黄放入锅中加入加500毫升清水，用猛火煮10分钟后，即可得到该药物。
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