CN107029086B - Traditional Chinese medicine composition for treating dandruff - Google Patents

Traditional Chinese medicine composition for treating dandruff Download PDF

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CN107029086B
CN107029086B CN201710386459.3A CN201710386459A CN107029086B CN 107029086 B CN107029086 B CN 107029086B CN 201710386459 A CN201710386459 A CN 201710386459A CN 107029086 B CN107029086 B CN 107029086B
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dandruff
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CN107029086A (en
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韩侠
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HUAIBEI JIULYU ENTERPRISE MANAGEMENT CONSULTATION Co.,Ltd.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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Abstract

The invention discloses a traditional Chinese medicine composition for treating dandruff, which is prepared from the following raw materials in parts by weight: 10-15 parts of mint, 5-8 parts of gentian, 15-20 parts of lotus leaf, 15-20 parts of aloe, 5-8 parts of borneol, 10-15 parts of coptis and 3-5 parts of liquorice; taking out the traditional Chinese medicine raw materials according to the weight part, cleaning the traditional Chinese medicine raw materials except the borneol, and then adding water for soaking; soaking, decocting, boiling, decocting with slow fire, repeating for 3 times, adding water, and filtering; heating the filtrate obtained by the three-time filtration at constant temperature, introducing the generated steam into a cooling tank, and adding Borneolum Syntheticum to obtain the preparation solution. The invention has the advantages of clearing heat, improving eyesight, comfortable use, removing dandruff and relieving itching, can obviously prolong and reduce the frequency of dandruff generation from the beginning of use, can prolong the generated large amount of dandruff from 1-2 days to 3-6 days, does not cause itching of the scalp after use, can basically solve the problems of large amount of dandruff generation and itching after continuous use for 4 weeks, and hardly causes relapse.

Description

Traditional Chinese medicine composition for treating dandruff
Technical Field
The invention relates to a traditional Chinese medicine composition for treating dandruff, and belongs to the technical field of traditional Chinese medicines.
Background
Dandruff is produced by a number of causes, and general skin dirt, i.e. the continually exfoliative surface of the stratum corneum of the epidermis, is also a result of metabolism. The problems that excessive dandruff causes hair weakness, bacteria easily proliferate and skin is stimulated to generate itching are caused by blocking pores, and the problems of dandruff and itching caused by fungi cannot be solved by simply relying on shampoo.
Ketoconazole is an imidazole antifungal drug, is widely applied to external washing of 2% ketoconazole lotion in clinical treatment to treat scalp seborrheic dermatitis, has good effects on scaly scalp and pruritus, and is found to have high recurrence rate in use. According to the traditional Chinese medicine, the seborrheic dermatitis of the scalp belongs to the category of seborrheic dermatitis, and the cause of seborrheic dermatitis is related to the affection of exogenous pathogenic factors such as wind, dampness, heat, insects and the like. Heat exists in the body, and the disease can be caused by external attack of wind-heat evil, long-term invasion of blood by evil depression, blood heat transforming into dryness to generate wind, or internal wind due to yin-blood deficiency to cause wind-heat dryness evil to block the skin, or by eating thick paste, spicy wine and the like to cause dysfunction of spleen and stomach transportation and transformation, dampness transforming into heat, dampness-heat accumulating in the skin, or external attack of evil factors such as insect pathogen with wind, dampness and the like to transform into heat and generate wind. Therefore, the application of the traditional Chinese medicine composition for treating dandruff aims at the traditional Chinese medicine pathology, and is an exploring method.
Disclosure of Invention
The invention aims to solve the problems and provides the traditional Chinese medicine composition for treating dandruff, which has a remarkable using effect, obviously reduces the frequency of dandruff generation, and has itching relieving and sterilizing effects.
In order to achieve the purpose, the invention adopts the technical scheme that: a traditional Chinese medicine composition for treating dandruff comprises the following raw materials in parts by weight: 10-15 parts of mint, 5-8 parts of gentian, 15-20 parts of lotus leaf, 15-20 parts of aloe, 5-8 parts of borneol, 10-15 parts of coptis and 3-5 parts of liquorice.
Further, the preparation method of the traditional Chinese medicine composition for treating dandruff comprises the following steps:
firstly, preparing materials: taking out the traditional Chinese medicine raw materials according to the weight part, cleaning the traditional Chinese medicine raw materials except the borneol, and then adding water to soak for 1-4 hours;
secondly, decocting: decocting the traditional Chinese medicine raw materials soaked in the step one, boiling the raw materials for 2-4 hours by slow fire after heating, filtering, adding water for the second time, boiling the raw materials by the slow fire for 1-2 hours after heating, adding water for the third time after filtering, boiling the raw materials by the slow fire for 1-2 hours after heating, and filtering again;
thirdly, preparation: and (4) superposing the filtrates filtered in the second and third steps, heating with slow fire at constant temperature, introducing the generated steam into a cooling tank for natural cooling, and simultaneously adding borneol into the cooling tank to obtain the preparation liquid.
Furthermore, the cooled preparation liquid is used for cleaning the head, and the dirt is cleaned by shampoo before cleaning.
Furthermore, the water adding amount in the first step is 3-4 times of that of the traditional Chinese medicine raw materials, and the water adding amount in the second step and the water adding amount in the third step are 2 times of that of the traditional Chinese medicine raw materials.
The invention has the beneficial effects that: the anti-dandruff shampoo has a reasonable formula, is capable of clearing heat and improving eyesight, is comfortable to use, can remove dandruff and relieve itching, can obviously prolong and reduce the frequency of dandruff generation from 1-2 days to 3-6 days, can not generate a large amount of dandruff, and can basically solve the problems of dandruff generation and itching after being continuously used for 4 weeks, and hardly returns.
Detailed Description
Example 1
A traditional Chinese medicine composition for treating dandruff comprises the following raw materials in parts by weight: 10-15 parts of mint, 5-8 parts of gentian, 15-20 parts of lotus leaf, 15-20 parts of aloe, 5-8 parts of borneol, 10-15 parts of coptis and 3-5 parts of liquorice.
The preparation method of the traditional Chinese medicine composition for treating dandruff comprises the following steps:
firstly, preparing materials: taking out the traditional Chinese medicine raw materials according to the weight part, cleaning the traditional Chinese medicine raw materials except the borneol, and then adding water to soak for 1-4 hours;
secondly, decocting: decocting the traditional Chinese medicine raw materials soaked in the step one, boiling the raw materials for 2-4 hours by slow fire after heating, filtering, adding water for the second time, boiling the raw materials by the slow fire for 1-2 hours after heating, adding water for the third time after filtering, boiling the raw materials by the slow fire for 1-2 hours after heating, and filtering again;
thirdly, preparation: and (4) superposing the filtrates filtered in the second and third steps, heating with slow fire at constant temperature, introducing the generated steam into a cooling tank for natural cooling, and simultaneously adding borneol into the cooling tank to obtain the preparation liquid.
The water adding amount in the first step is 3-4 times of that of the traditional Chinese medicine raw materials, and the water adding amount in the second step and the water adding amount in the third step are 2 times of that of the traditional Chinese medicine raw materials.
The cooled preparation liquid is used for cleaning head, and shampoo is used for cleaning dirt before cleaning.
The medicine properties of the traditional Chinese medicine raw materials are as follows:
mint: pungent taste and cool nature. The traditional Chinese medicine composition enters lung and liver channels, has the effects of dispelling wind heat, clearing and removing heat from throat, promoting eruption and detoxifying, soothing liver and relieving depression, relieving itching and the like, has the effect of stimulating central nerve, has burning and cold feeling when being acted on skin, and has the effects of inhibiting and paralyzing sensory nerve endings; has antiallergic and antipruritic effects on skin pruritus, and has obvious relieving and analgesic effects on neuralgia and rheumatic arthralgia.
Gentian: the traditional Chinese medicine composition is bitter in taste and cold in nature, enters lung and liver channels, clears heat and dries dampness, purges liver and relieves convulsion, and is a substance with big cold in head fullness and headache and conjunctival congestion and swelling and pain caused by excessive fire of liver and gallbladder, and the dosage is also considered for external use, so the weight parts given by the application after research cannot be adjusted freely.
Lotus leaf: bitter and astringent taste, neutral in nature, entering liver, spleen, stomach and heart meridians. Has effects of clearing summer-heat, promoting diuresis, raising hair, clearing yang, cooling blood, and stopping bleeding.
Aloe vera: the aloe tincture can kill various fungi, mould, bacteria, viruses and other germs, and inhibit and eliminate the development and reproduction of pathogens; aloe bradykinin peptidase in combination with vascular tone can counteract inflammation. Aloe polysaccharide and vitamins have nourishing, moistening and whitening effects on human skin. The aloe calcium isocitrate has effects of tonifying heart, promoting blood circulation, softening and hardening artery, reducing cholesterol content, dilating capillary vessel, promoting blood circulation, and removing "toxin" in blood. Aloin A, wound hormone and glycan peptide manna (Ke-2) have effects of resisting virus infection, promoting wound healing and recovering, and have effects of diminishing inflammation, sterilizing, absorbing heat, relieving swelling, softening skin, and maintaining cell activity, and curdlan and callus acid have wound healing activity. Through aloe, blood vessels are repaired, sterilization, inflammation diminishing and wound healing are achieved, scalp damage is reduced, and scalp environment is repaired.
Borneol: unblocking orifices, dispelling stagnated fire, removing nebula, improving eyesight, relieving swelling and alleviating pain. Has analgesic and antiseptic effects, has antibacterial effects in vitro, can be used for treating neuralgia and inflammation, is easily absorbed by mucosa and subcutaneous tissue, and can be combined with glucuronic acid in vivo and then discharged out of body.
Coptis chinensis: bitter, cold and non-toxic. It enters heart, spleen, stomach, liver, gallbladder and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity.
Licorice root: neutral in nature and sweet in flavor, it enters twelve meridians. Has the pharmacological actions of detoxification, phlegm elimination, pain relief, spasmolysis and cancer resistance. The traditional Chinese medicine has the effects of tonifying spleen and qi, relieving urgency and detoxifying, harmonizing various medicines, resisting bacteria and diminishing inflammation.
Example 2
As a best embodiment, the traditional Chinese medicine composition for treating dandruff comprises the following raw materials in parts by weight: 13 parts of mint, 6 parts of gentian, 18 parts of lotus leaf, 18 parts of aloe, 6 parts of borneol, 12 parts of coptis root and 4 parts of liquorice.
Example 3
In this example, 50 persons with excessive dandruff and itching were sampled, and the age groups included 12 to 60 years (the occurrence of such problems after 60 years of age was low), and were randomly divided into 5 groups. The comparison difference of five groups of data has no statistical significance and is comparable.
The best example given in example 2 was used as 1 group, the random combination of the raw materials in example 1 was used as 2 groups, and the maximum and minimum values of the boundary values in example 1 were used as 1 group.
Soaking and massaging scalp, washing the scalp after the medicinal liquid is retained for not less than 10min, and recording the feeling of each group after the second washing time is 3 days.
The test is limited to 4 weeks, and the curative effect statistics are carried out.
The criteria for efficacy are as follows,
and (3) healing: dandruff returns to normal level, and scalp damage returns to normal;
the effect is shown: the pruritus is obviously relieved, and the generation time of a large amount of dandruff is 3 days or more;
the method has the following advantages: the pruritus is reduced, and the dandruff generation amount is reduced compared with the initial stage;
and (4) invalidation: the improvement was not significant or exacerbated.
The five groups of the comparison table are as follows:
group of Recovery method Show effect Is effective Invalidation
1 (adopted example 2) 10 0 0 0
2 (random example 1) 6 3 1 0
3 (random example 1) 5 2 3 0
4 (minimum of example 1) 5 3 2 0
5 (maximum in example 1) 8 2 0 0
As can be seen from the comparison table, 1, no ineffectiveness exists, the total effective rate is 100 percent, and the effect of the formula has universal curative effect. 2. The effective rate is 12%, the obvious effect rate is 20%, the recovery rate is 68%, the medicine is not used after recovery, and no repetition is found in the test period.
The invention has reasonable formula, clears heat and improves eyesight, is comfortable to use, removes dandruff and relieves itching, can obviously prolong and reduce the frequency of dandruff generation from the beginning of use, prolongs a large amount of dandruff from 1-2 days to 3-6 days, does not cause itching of scalp after use, can basically solve the problems of a large amount of dandruff generation and itching after continuous use for 4 weeks, and hardly causes relapse.
The embodiments of the present application are only used for illustrating the technical features disclosed in the present application, and the changes made by the simple substitution by those skilled in the art still belong to the protection scope of the present application.

Claims (3)

1. A traditional Chinese medicine composition for treating dandruff comprises the following raw materials in parts by weight: 10-15 parts of mint, 5-8 parts of gentian, 15-20 parts of lotus leaf, 15-20 parts of aloe, 5-8 parts of borneol, 10-15 parts of coptis and 3-5 parts of liquorice;
the preparation method comprises the following steps:
firstly, preparing materials: taking out the traditional Chinese medicine raw materials according to the weight part, cleaning the traditional Chinese medicine raw materials except the borneol, and then adding water to soak for 1-4 hours;
secondly, decocting: decocting the traditional Chinese medicine raw materials soaked in the step one, boiling the raw materials for 2-4 hours by slow fire after heating, filtering, adding water for the second time, boiling the raw materials by the slow fire for 1-2 hours after heating, adding water for the third time after filtering, boiling the raw materials by the slow fire for 1-2 hours after heating, and filtering again;
thirdly, preparation: superposing the filtrates filtered in the second and third steps, heating with slow fire at constant temperature, introducing the generated steam into a cooling tank for natural cooling, and simultaneously adding borneol into the cooling tank to obtain a preparation solution; when in use, the cooled preparation liquid is used for cleaning the head, and the shampoo is used for cleaning dirt before cleaning.
2. The traditional Chinese medicine composition for treating dandruff according to claim 1, characterized in that: the water adding amount in the first step is 3-4 times of that of the traditional Chinese medicine raw materials, and the water adding amount in the second step and the water adding amount in the third step are 2 times of that of the traditional Chinese medicine raw materials.
3. The traditional Chinese medicine composition for treating dandruff according to claim 1, characterized in that: the composition is characterized by comprising the following raw materials in parts by weight: 13 parts of mint, 6 parts of gentian, 18 parts of lotus leaf, 18 parts of aloe, 6 parts of borneol, 12 parts of coptis root and 4 parts of liquorice.
CN201710386459.3A 2017-05-26 2017-05-26 Traditional Chinese medicine composition for treating dandruff Active CN107029086B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101327286A (en) * 2008-07-23 2008-12-24 中山大学 Pain-relieving anti-inflammation medicament and preparation method thereof and use
CN102008417A (en) * 2010-12-10 2011-04-13 韩萍萍 Shampoo formula for the treatment of scalp itching

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101327286A (en) * 2008-07-23 2008-12-24 中山大学 Pain-relieving anti-inflammation medicament and preparation method thereof and use
CN102008417A (en) * 2010-12-10 2011-04-13 韩萍萍 Shampoo formula for the treatment of scalp itching

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