CN107027801A - A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof - Google Patents
A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof Download PDFInfo
- Publication number
- CN107027801A CN107027801A CN201710492093.8A CN201710492093A CN107027801A CN 107027801 A CN107027801 A CN 107027801A CN 201710492093 A CN201710492093 A CN 201710492093A CN 107027801 A CN107027801 A CN 107027801A
- Authority
- CN
- China
- Prior art keywords
- mti
- parts
- cyanogen insect
- bromine cyanogen
- suspending agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof, are related to rice hoppers Prevention Technique field.At least by 8 parts of bromine cyanogen insect amides, 32 parts of MTI-446s, 6 parts of sodium methylene bis-naphthalene sulfonates, 2 parts of xanthans, 2 parts of ammonium lauryl sulfates, 15 parts of emulsifying agents 602 and complement to 100 parts of methyl oleate and be made.Raw material is pumped into and prepared after kettle is mixed through being ground at the beginning of colloid mill, then through sand mill fine grinding, sampling analysis, it is qualified after filtering, metering, packaging, storage.The present invention is with 1：4 proportionings it is mixed compounded 40% when bromine cyanogen insect amides and MTI-446 compound dispersible oil-suspending agent, can play notable synergistic sphere of action, and the mixed preparation of other proportionings, be unable to reach notable synergistic sphere of action.
Description
Technical field
The present invention relates to rice hoppers Prevention Technique field, a kind of bromine cyanogen insect amide and MTI-446 compounding are specifically related to
Dispersible oil-suspending agent and preparation method thereof.
Background technology
At present, the existing Pesticidal combination prevented and treated for rice hoppers, such as Chinese patent " CN 103583552
A " is disclosed a kind of " being used for the composition for preventing and treating planthopper ", and wherein active ingredient is beta-cypermethrin and pymetrozine,
The weight ratio of wherein beta-cypermethrin and pymetrozine is, beta-cypermethrin：Pymetrozine=5：1-15：1.Separately
Outside, Chinese patent " A of CN 103053568 " discloses a kind of " compounded pesticides for preventing and treating rice hoppers ", wherein effectively into
It is divided into two kinds of components of pyridaben and Bassa, wherein, the mass ratio of pyridaben and Bassa is 4:1~1:128.
Inventor verifies that above-mentioned several Pesticidal combinations are primarily present following defect by long term test：
1), by testing several specific proportionings disclosed in above-mentioned several Pesticidal combinations, find to fly paddy rice rice
Lice can not play good prevention effect.
2), for several formulations disclosed in above-mentioned several Pesticidal combinations, find there is difference by verification experimental verification
The defect of problem.For example, the wettable powder being made easily causes product to bond, it is difficult in water to disperse suspension, or block spray
Head, in sprayer reason precipitation etc. phenomenon, cause sprinkling it is irregular, easily make crop locally produce poisoning, itself main reason is that
There are different defects in the selection of auxiliary agent and filler.
3) problem, is compounded, by carrying out virulence test, heat to several specific proportionings disclosed in above-mentioned several Pesticidal combinations
Store stability test and co-toxicity coefficient is determined and found, be unable to reach obvious addition synergistic effect.
The content of the invention
An object of the present invention is that providing a kind of bromine cyanogen insect amide and MTI-446 compounds dispersible oil-suspending agent, and this can
Scattered oil-suspending agent is reasonable in design, and the prevention effect to rice hoppers is good, and can realize the bright of bromine cyanogen insect amide and MTI-446
Aobvious synergistic effect.
To achieve the above object, present invention employs following technical scheme：
A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, are at least made up of the component of following parts by weight：
Bromine cyanogen insect amide is E.I.Du Pont Company's second generation ryanodine receptor inhibitor class that success is developed after chlorantraniliprole
Insecticide, cyanogen insect amide is formed by the various polar groups changed on phenyl ring, with more efficient, and applicable crops are more extensive,
Lepidoptera, Semiptera and coleopteran pest can effectively be prevented and treated.
MTI-446 is the super nicotinic insecticide of latest generation.The chemical constitution of itself and existing nicotinic insecticide is
Far from each other, its tetrahydrofuran base instead of former chloro-pyridine base, chloro-thiazole base, without halogen.Meanwhile,
Also different with nicotine in aspect of performance, insecticidal spectrum is wider, so, current people are referred to as " furans nicotine ".
The bromine cyanogen insect amide and MTI-446 of the present invention compounds dispersible oil-suspending agent, and its advantage is shown：
1), dispersible oil-suspending agent prepared by the present invention is in terms of suspensibility, wet screening experiment etc. and heat storage stability
It is significantly better than that the prepared product of other proportionings.
2), by experimental verification, bromine cyanogen insect amide and MTI-446 are with 1：4 proportionings use bromine cyanogen worm during compounded 40% with
Acid amides and MTI-446 compound dispersible oil-suspending agent, can play obvious addition synergistic effect scope, and the mixed system of other proportionings
Agent, is unable to reach obvious addition synergistic effect scope.Meanwhile, the actual toxicity of different ratio is not with the increasing of theoretical toxicity
Lifted by force, regular change is had no between actual toxicity and theoretical toxicity.
Another object of the present invention is to provide a kind of bromine cyanogen insect amide and MTI-446 to compound the system of dispersible oil-suspending agent
Preparation Method, raw material is pumped into and prepared after kettle is mixed through being ground at the beginning of colloid mill, then through sand mill fine grinding, sampling analysis is qualified
Filter, measure, pack, be put in storage afterwards.
The bromine cyanogen insect amide and MTI-446 of the present invention compound the preparation method of dispersible oil-suspending agent, and preparation technology is more simple
Just, it is easy to industrialized production.
Embodiment
Below with reference to embodiment, the present invention is described in detail.But, embodiment content is only to this hair
Bright example and explanation, affiliated those skilled in the art do various repair to described specific embodiment
Change or supplement or substituted using similar mode, design without departing from invention or surmount defined in the claims
Scope, all should belong to protection scope of the present invention.
First, bromine cyanogen insect amide and MTI-446 compound the preparation of dispersible oil-suspending agent, and prepared by each embodiment can
Testing result, the heat storage stability result of the test of all technical of scattered oil-suspending agent.
Embodiment 1
40% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
Preparation method：Raw material is pumped into and prepared after kettle is mixed through being ground at the beginning of colloid mill, then through sand mill fine grinding, sampling
Analysis, qualified rear filtering, metering, packaging, storage.
Embodiment 2
39% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
| Composition | Parts by weight |
| Bromine cyanogen insect amide | 8 |
| MTI-446 | 31 |
| Sodium methylene bis-naphthalene sulfonate | 6 |
| Xanthans | 2 |
| Ammonium lauryl sulfate | 2 |
| Emulsifying agent 602 | 15 |
| Methyl oleate | Complement to 100 |
Preparation method be the same as Example 1.
Embodiment 3
38% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
Preparation method be the same as Example 1.
Embodiment 4
41% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
| Composition | Parts by weight |
| Bromine cyanogen insect amide | 9 |
| MTI-446 | 32 |
| Sodium methylene bis-naphthalene sulfonate | 6 |
| Xanthans | 2 |
| Ammonium lauryl sulfate | 2 |
| Emulsifying agent 602 | 15 |
| Methyl oleate | Complement to 100 |
Preparation method be the same as Example 1.
Embodiment 5
42% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
| Composition | Parts by weight |
| Bromine cyanogen insect amide | 9 |
| MTI-446 | 33 |
| Sodium methylene bis-naphthalene sulfonate | 6 |
| Xanthans | 2 |
| Ammonium lauryl sulfate | 2 |
| Emulsifying agent 602 | 15 |
| Methyl oleate | Complement to 100 |
Preparation method be the same as Example 1.
Embodiment 6
40% bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, and each component and its parts by weight are as follows：
Preparation method be the same as Example 1.
Bromine cyanogen insect amide and MTI-446 prepared by embodiment 1~6 compound dispersible oil-suspending agent, and product items technology refers to
As shown in table 1, product heat storage stability result of the test is as shown in table 2 for target testing result.
16 embodiments of table prepare the testing result of product all technical
26 embodiments of table prepare product heat storage stability result of the test
By table 1 and 2 as can be seen that product prepared by embodiment 1 and 6 stores steady in suspensibility, wet screening experiment etc. and heat
The product prepared by other embodiment is significantly better than that in terms of qualitative.
2nd, toxicological information
Bromine cyanogen insect amide：Toxicity LD50(mg/kg)：Rat acute is more than 5500, and acute percutaneous is more than 2500.To rabbit
Eyes and skin minimal irritation.Without teratogenesis, mutagenesis, carcinogenesis.
MTI-446：It is fool proof to mammal, its acute oral LD50For male rat 2450mg/kg, female rats
2275mg/kg；Male mice 2840mg/kg, female mice 2000mg/kg.LD percutaneous to rat acute50>2000mg/kg (female,
It is male).Without teratogenesis, carcinogenic and mutagenicity.It is also fool proof to aquatile.
3rd, bromine cyanogen insect amide and MTI-446 compound indoor biological active (virulence) measure of dispersible oil-suspending agent.
1 introduction
What MTI-446 and bromine cyanogen insect amide were combined into is killed by the systematicness of spinal nerves transmission and stomach poison function of tagging
Worm agent, can quickly be absorbed by plants wide dispersion, there is excitation to nAChR, desinsection knock down speed compared with
It hurry up, the lasting period is longer, prevent and treat rice hoppers effect preferable.Now with regard to after MTI-446 and two kinds of pharmacy mix of bromine cyanogen insect amide to water
The synergy of rice planthopper and optimum proportioning are tested.
2 materials and methods
2.1 reagent agents and mixed formula design：
1. MTI-446, Anhui Meilan Agricultural Development Co., Ltd. provides；
2. bromine cyanogen insect amide, Anhui Meilan Agricultural Development Co., Ltd. provides；
2.2 mixed formula designs
It is designed with the proportioning given by embodiment 1-6 totally 6 embodiments.
2.3 for examination insect
Planthopper random acquisition planthopper nymph from Hefei City Feixi County little Miao towns Guai Gang villages rice terrace, selects growth hair
Educate normal, polypide enlivens that size is relatively uniform, and the strong individual nymph of viability makees toxicity test test worm.
2.4 assay method
Quantitatively weigh after active compound dilution by than row configuration mixture.Mother liquor first is made by solvent of acetone in medicament, is stored in
It is standby in refrigerator.Diluted with mother liquor with acetone, medicament is designed to 5-6 series concentration.By planthopper be put into culture dish (1/
Culture dish) in, with micro intravenous drip instrument by decoction drop in the planthopper chest back side.Before formal determine, metering model is first carried out
Enclose the pilot study of measure.During measure, each concentration handles 20 larvas, and makees blank control with acetone.In 26 DEG C of insulating boxs
It is middle culture 24 hours after inspection result.The death rate is calculated according to the dead borer population of total borer population, is corrected with the control death rate.With dead
Die rate value and dosage logarithm carries out linear regression, calculate LD50Value, calculates co-toxicity coefficient (C.T.C)
3 results
The 3.1 MTI-446s virulence to rice hoppers larva mixed with bromine cyanogen insect amide
MTI-446 and bromine cyanogen insect amide are shown with 6 kinds of not mixed toxicity tests to rice hoppers larva of row on year-on-year basis, data
Show, in each measured different ratio, the virulence highest of embodiment 6, LD50For 3.30565/；The virulence time of embodiment 1
It, LD50For 3.28756/, the not ideal (LD of the proportioning shown in embodiment 2-5 of virulence of other proportionings50It is followed successively by
4.85533/, 5.66481/, 5.36292/, 5.25036/).
The synergy reaction mixed with bromine cyanogen insect amide of 3.2 MTI-446s
The synergy reaction of two or more pharmacy mix represents that synergy is anti-with co-toxicity coefficient (C.T.C)
Three types, i.e. antagonism (C.T.C ＜ 70), summation action (C.T.C70~150) and synergistic effect (C.T.C ＞ should be divided into
150).In 6 measured mixed preparations, embodiment 1 and 6 belongs to synergistic effect scope, and co-toxicity coefficient is respectively reached
178.2nd, 180.5, the mixed preparation of other proportionings, is that (co-toxicity coefficient of the proportioning shown in embodiment 2-5 is successively for summation action
For 78,88,75,70).
In summary, the synergy of the compound proportion of embodiment 1 and 6 belongs to obvious addition synergistic effect, and other realities
The synergy for applying example substantially belongs to addition.Meanwhile, it can be seen that by the experiment of embodiment 6 and compounding dispersible oil
It with the addition of in suspending agent after a small amount of cyclomulberrochromene, the compounding synergy of bromine cyanogen insect amide and MTI-446 can be made further
Lifting.
Claims (2)
1. a kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent, it is characterised in that：At least by following parts by weight
Component is made：
2. a kind of prepare the method that bromine cyanogen insect amide as claimed in claim 1 and MTI-446 compound dispersible oil-suspending agent, it is special
Levy and be：Raw material is pumped into and prepared after kettle is mixed through being ground at the beginning of colloid mill, then through sand mill fine grinding, sampling analysis is qualified
Filter, measure, pack, be put in storage afterwards.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710492093.8A CN107027801A (en) | 2017-06-26 | 2017-06-26 | A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710492093.8A CN107027801A (en) | 2017-06-26 | 2017-06-26 | A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107027801A true CN107027801A (en) | 2017-08-11 |
Family
ID=59541644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710492093.8A Withdrawn CN107027801A (en) | 2017-06-26 | 2017-06-26 | A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107027801A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246186A (en) * | 2021-12-22 | 2022-03-29 | 天津市汉邦植物保护剂有限责任公司 | Dispersible oil suspending agent containing kojic acid and cyantraniliprole as well as preparation method and application thereof |
-
2017
- 2017-06-26 CN CN201710492093.8A patent/CN107027801A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246186A (en) * | 2021-12-22 | 2022-03-29 | 天津市汉邦植物保护剂有限责任公司 | Dispersible oil suspending agent containing kojic acid and cyantraniliprole as well as preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103053609B (en) | Glufosinate-picolinic acid herbicide weeding composition | |
| CN104621140A (en) | Sugarcane field herbicide for low-volume spraying | |
| CN104145975B (en) | A kind of Herbicidal combinations and preparation thereof | |
| CN105519531A (en) | Clodinafop-propargyl and beflubutamid containing weeding composition and application thereof | |
| CN106259368B (en) | A kind of corn field mixed herbicide containing isoxaflutole | |
| CN107027801A (en) | A kind of bromine cyanogen insect amide and MTI-446 compound dispersible oil-suspending agent and preparation method thereof | |
| CN102405916A (en) | Herbicidal composition containing fenoxaprop-P-ethyl and bentazone | |
| CN103371174A (en) | Weeding composition containing glufosinate-ammonium and amides | |
| CN105284856A (en) | Weeding combination containing halauxifen-methyl and thiencarbazone-methyl | |
| CN104604907B (en) | A kind of Herbicidal combinations and application thereof containing Mediben and pyributicarb | |
| CN103598195B (en) | Mixed herbicide containing clodinafop-propargyl and procarbazone sodium | |
| CN103371158B (en) | A kind of Herbicidal combinations containing AC322140 | |
| CN106386813B (en) | Herbicidal combinations and its application | |
| CN104839171A (en) | Weeding composition containing triazole napropamide and oxyfluorfen | |
| CN104839226A (en) | Combined nematicide | |
| CN104604915A (en) | Dicamba and pyrazosulfuron-ethyl herbicidal composition and application thereof | |
| CN103749512B (en) | A kind of containing flucarbazone with the Herbicidal combinations of Sulfonylurea | |
| CN102461506B (en) | Mixed herbicide composition containing bispyribac-sodium and pyriminobac-methyl | |
| CN103688940B (en) | A kind of containing pyraflufen-ethyl with the Herbicidal combinations of fluroxypyr | |
| CN105410006A (en) | Dinotefuran and nitenpyram compound water dispersible granule and preparation method thereof | |
| CN105379742A (en) | Compound weeding composition containing clodinafop-propargyl and methabenzthiazuron and application thereof | |
| CN105340912A (en) | Complex herbicide | |
| CN105360123A (en) | Composite weeding composition containing clodinafop-propargyl and indanofan and application of composite weeding composition | |
| CN103749511B (en) | A kind of containing flucarbazone with the Herbicidal combinations of monosulfmeturon | |
| CN104488917A (en) | Weeding composition containing diflufenican and pyroxsulam |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170811 |