CN107014667A - A kind of lyophilized reaction vessel - Google Patents

A kind of lyophilized reaction vessel Download PDF

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Publication number
CN107014667A
CN107014667A CN201710338292.3A CN201710338292A CN107014667A CN 107014667 A CN107014667 A CN 107014667A CN 201710338292 A CN201710338292 A CN 201710338292A CN 107014667 A CN107014667 A CN 107014667A
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CN
China
Prior art keywords
cup
reaction vessel
interior
reagent
reagent chamber
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Granted
Application number
CN201710338292.3A
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Chinese (zh)
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CN107014667B (en
Inventor
余枝广
印帅
吴林涛
董俊
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Medcaptain Medical Technology Co Ltd
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Medcaptain Medical Technology Co Ltd
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Priority to CN201710338292.3A priority Critical patent/CN107014667B/en
Publication of CN107014667A publication Critical patent/CN107014667A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42Low-temperature sample treatment, e.g. cryofixation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of lyophilized reaction vessel, including outer cup and interior cup;The cup inner bottom part of the outer cup is provided with the reagent chamber for accommodating reagent, and the reagent chamber has an opening upward;The interior glass holder is located in the outer cup, and the cup bottom of the interior cup is resisted against the opening of the reagent chamber, and the reagent chamber is sealed.By setting reagent chamber in the bottom of outer cup, reagent can conveniently be accommodated, the cup bottom of interior cup is resisted against the opening of reagent chamber, and confined space is formed in reagent chamber, so that reagent is sealed between interior cup and outer cup, cup can expose reagent in being taken out when using, adding blood can be tested, convenient use, make full use of the structure setting reagent of outer cup and interior cup, it is simple in construction, reduce cost.

Description

A kind of lyophilized reaction vessel
Technical field
The present invention relates to the consumptive material field of thrombelastogram instrument, more particularly to a kind of lyophilized reaction vessel.
Background technology
Need to use a kind of reaction vessel on thrombelastogram instrument to carry reagent and blood.Reaction vessel is common with reagent As the consumptive material of thrombelastogram instrument, reagent is put into reaction vessel when in use, blood is added and is reacted.
For the ease of the transport and storage of reagent, portion of reagent needs to carry out frozen dried, to remove the moisture in reagent, It can be used to test after adding double solvents dissolving in freeze-dried powder when using.
Usual the lyophilized of thrombelastogram reagent has two kinds of processing modes:One kind is that directly reagent is placed in reaction vessel Freezed, because reaction vessel can not be sealed, therefore freeze-dried powder can make moist in storing process, and reagent, which makes moist, can influence reagent Use;Another is to freeze reagent in special lyophilized bottle, adds after double solvents dissolving, makes in lyophilized bottle when using With pipettor by reagent from lyophilized bottle moves into reaction vessel, the method operation is relatively complicated, and each reaction vessel is required for An extra lyophilized bottle is equipped with, increases cost.
The content of the invention
The technical problems to be solved by the invention are there is provided a kind of lyophilized reaction vessel, simple in construction, are easy to accommodating examination Agent, reduces cost.
In order to solve the above-mentioned technical problem, The embodiment provides a kind of lyophilized reaction vessel, including outer cup and Interior cup;The cup inner bottom part of the outer cup is provided with the reagent chamber for accommodating reagent, and the reagent chamber has an opening upward; The interior glass holder is located in the outer cup, and the cup bottom of the interior cup is resisted against the opening of the reagent chamber, and by the reagent chamber Sealing.
Wherein, the lyophilized reaction vessel also includes cup lid, and the cup lid is removably attachable to the rim of a cup of the outer cup, The interior cup is pressed between the bottom of the cup lid and the outer cup.
Wherein, the lyophilized reaction vessel also includes sealing gasket, and the sealing gasket is arranged on the cup lid and the outer cup Between, to form confined space in the outer cup.
Wherein, the periphery of the sealing gasket is resisted against the rim of a cup of the outer cup, and is pressed on the cup lid and the outer cup Rim of a cup between, the inboard portion of the sealing gasket is resisted against above the rim of a cup of the interior cup, and be pressed on the cup lid with it is interior Between cup.
Wherein, the rim of a cup upper surface of the outer cup is concordant with the rim of a cup upper surface of the interior cup.
Wherein, the reagent chamber is recessed by the inner bottom surface of the outer cup and formed;Or,
Circumference on the madial wall of the outer cup around the outer cup is formed with annular and separation piece, positioned at the annular and separation piece Cavity between the inner bottom wall of the outer cup forms the reagent chamber, and the inner side of the annular and separation piece forms the reagent chamber Opening.
Wherein, the reagent chamber is one, at the bottom centre position of the outer cup.
Wherein, it is formed with inclined-plane between the opening and the madial wall of the outer cup of the reagent chamber.
Wherein, the bottom peripheral edge of the interior cup is provided with bevelling.
Wherein, the rim of a cup of the interior cup and the rim of a cup of the outer cup are detachable connection.
The lyophilized reaction vessel that the present invention is provided, by setting reagent chamber in the bottom of outer cup, can conveniently accommodate reagent, The cup bottom of interior cup is resisted against the opening of reagent chamber, and confined space is formed in reagent chamber, so that reagent is sealed in into interior cup and outer Cup can expose reagent in being taken out between cup, when using, and adding blood can be tested, convenient use, make full use of outer The structure setting reagent of cup and interior cup, it is simple in construction, reduce cost.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing There is the accompanying drawing used required in technology description to be briefly described, it should be apparent that, drawings in the following description are only this Some embodiments of invention, for those of ordinary skill in the art, without having to pay creative labor, may be used also To obtain other accompanying drawings according to these accompanying drawings.
Fig. 1 is the axial sectional view for the lyophilized reaction vessel that the preferred embodiment of the present invention is provided.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation is described.
A kind of lyophilized reaction vessel that preferred embodiment is provided in the present invention, for the supporting freeze-dried reagent of thrombelastogram instrument Carrying and storage;Also can be used for other extracorporeal diagnostic instruments it is supporting have lyophilized demand reagent or without it is lyophilized requirement but have close Envelope requires the carrying and storage of reagent.
Fig. 1 is referred to, freezing reaction vessel includes outer cup 1 and interior cup 2, and the cup inner bottom part of outer cup 1 is provided with for accommodating The reagent chamber 10 of reagent, reagent chamber 10 has an opening upward;Interior cup 2 is set in outer cup 1, and the cup bottom of interior cup 2 is resisted against The opening of reagent chamber 10, and reagent chamber 10 is sealed.
By setting reagent chamber 10 in the bottom of outer cup 1, reagent can be conveniently accommodated, the cup bottom of interior cup 2 is resisted against reagent The opening of chamber 10, confined space is formed in reagent chamber 10, so as to reagent is sealed between interior cup 2 and outer cup 1, to ensure examination Agent dry powder will not make moist, and be flown out while being prevented effectively from the reagent dry powder in transportation outside reagent chamber 10.Cup 2 in being taken out when using Reagent can be exposed, adding blood can be tested, convenient use, make full use of outer cup 1 and the structure setting of interior cup 2 to try Agent, it is simple in construction, reduce cost.
In the present embodiment, lyophilized reaction vessel also includes cup lid 3, and cup lid 3 is removably attachable to the rim of a cup of outer cup 1, interior Cup 2 is pressed between the bottom of cup lid 3 and outer cup 1.Using cup lid 3, inwardly active force can be applied by cup 2, so that interior cup 2 It is effectively that reagent chamber 10 is closed tight against the cup inner bottom part of outer cup 1, it is ensured that reagent will not make moist.Cup lid 3 can be connected with screw thread The rim of a cup of outer cup 1 is connected to, gradually inside cup 2 applies active force during tightening so that interior cup 2 is in close contact with outer cup 1, Easy disassembly simultaneously;Certainly, in other embodiments, cup lid 3 can also removably be connected by other modes such as buckles To outer cup 1.
Lyophilized reaction vessel further comprises sealing gasket 4, and sealing gasket 4 is arranged between cup lid 3 and outer cup 1, with outside Confined space is formed in cup 1, reagent, which is further effectively ensured, to make moist.
The periphery of sealing gasket 4 is resisted against the rim of a cup of outer cup 1, and is pressed between the rim of a cup of cup lid 3 and outer cup 1, realizes cup Sealing between lid 3 and outer cup 1.The inboard portion of sealing gasket 4 is resisted against above the rim of a cup of interior cup 2, and be pressed on cup lid 3 with it is interior Between cup 2, the active force of cup lid 3 can be transferred to interior cup 2 using sealing gasket 4, also sealing gasket 4 has certain elasticity, can Remain that inside cup 2 applies active force in transportation, the sealing property of reagent chamber 10 is effectively ensured.Herein, at other In embodiment or sealing gasket 4 is provided only between cup lid 3 and outer cup 1, and directly inwardly cup 2 applies by cup lid 3 Active force.
The rim of a cup outer peripheral edge of interior cup 2 is provided with annular flange 22, and annular flange 22 is connected to sealing gasket 4, utilizes convex annular Edge 22, can increase the contact area between interior cup 2 and sealing gasket 4, sealing is effectively ensured, while can be using sealing gasket 4 more Equably inside cup 2 applies active force.
The rim of a cup upper surface of outer cup 1 is concordant with the rim of a cup upper surface of interior cup 2, can be same using sealing gasket 4 in uniform thickness When be in close contact with the rim of a cup of the rim of a cup of outer cup 1, interior cup 2, it is prepared by convenient processing.Sealing gasket 4 can be fixedly connected on cup lid 3 Inner surface, so that convenient for assembly and dismounting is used.
Reagent chamber 10 is recessed by the inner bottom surface of outer cup 1 and formed, so that reagent chamber 10 has an opening upward, it is convenient The machine-shaping of reagent chamber 10.Herein, in other embodiments or, it is circumferential around outer cup 1 on the madial wall of outer cup 1 Be formed with annular and separation piece, annular and separation piece will be divided into outer cup 1 above and below two parts, lower cavity is located at annular and separation piece Cavity formation reagent chamber 10 between the inner bottom wall of the outer cup 1, the inner side of annular and separation piece forms the opening of reagent chamber 10, The bottom of interior cup 2 is resisted against the inner side of annular and separation piece, so that by the closure of openings of reagent chamber 10.
In the present embodiment, reagent chamber 10 is one, at the bottom centre position of outer cup 1.Certainly, also may be used as needed To set multiple reagent chambers 10 in bottom, the bottom of interior cup 2 can set multiple projections, bear against in multiple reagent chambers 10 Opening, so that each reagent chamber 10 be sealed.
Inclined-plane 11 is formed between the opening of reagent chamber 10 and the madial wall of outer cup 1.Inclined-plane 11 is around reagent chamber 10 Ring-type, inclined-plane 11 is gradually reduced from the madial wall of outer cup 1 to the height of reagent chamber 10.It can conveniently make to load on call outside using inclined-plane 11 Reagent in cup 1 can be automatically flowed into reagent chamber 10 before freezing, and facilitate reagent filling.
The bottom peripheral edge of interior cup 2 is provided with bevelling 21 so that the bottom of interior cup 2 is in taper type, so that the bottom of cup 2 in convenient Portion and the opening of reagent chamber 10 coordinate, and make it have certralizing ability, convenient interior positioning assembling between cup 2 and outer cup 1.
In the above-described embodiment, using cup lid 3 cause in cup 2 tight against the bottom of outer cup 1, and in completing cup 2 with Fixing assembling between outer cup 1, in other embodiments or, the rim of a cup of interior cup 2 and the rim of a cup of outer cup 1 be screw thread, The detachable connections such as buckle, are directly connected as an entirety, and the interior bottom of cup 2 is sealed in examination all the time by interior cup 2 and outer cup 1 The opening of agent chamber 10, can set sealing ring, to ensure the sealing effectiveness of reagent chamber 10, sealing ring can between interior cup 2 and outer cup 1 To be arranged between the rim of a cup of the two, between the bottom that the two can also be arranged on.
Embodiment above, does not constitute the restriction to the technical scheme protection domain.It is any in above-mentioned embodiment Spirit and principle within the modifications, equivalent substitutions and improvements made etc., should be included in the technical scheme protection domain it It is interior.

Claims (10)

1. a kind of lyophilized reaction vessel, it is characterised in that including outer cup and interior cup;The cup inner bottom part of the outer cup, which is provided with, to be used for The reagent chamber of reagent is accommodated, the reagent chamber has an opening upward;The interior glass holder is located in the outer cup, the interior cup Cup bottom be resisted against the opening of the reagent chamber, and the reagent chamber is sealed.
2. lyophilized reaction vessel according to claim 1, it is characterised in that the lyophilized reaction vessel also includes cup lid, The cup lid is removably attachable to the rim of a cup of the outer cup, the interior cup be pressed on the cup lid and the outer cup bottom it Between.
3. lyophilized reaction vessel according to claim 2, it is characterised in that the lyophilized reaction vessel also includes sealing Pad, the sealing gasket is arranged between the cup lid and the outer cup, to form confined space in the outer cup.
4. lyophilized reaction vessel according to claim 3, it is characterised in that the periphery of the sealing gasket is resisted against described outer The rim of a cup of cup, and is pressed between the rim of a cup of the cup lid and the outer cup, and the inboard portion of the sealing gasket is resisted against described Above the rim of a cup of interior cup, and it is pressed between the cup lid and interior cup.
5. lyophilized reaction vessel according to claim 4, it is characterised in that the rim of a cup upper surface of the outer cup with it is described interior The rim of a cup upper surface of cup is concordant.
6. lyophilized reaction vessel according to claim 1, it is characterised in that the reagent chamber by the outer cup inner bottom surface Depression is formed;Or,
Circumference on the madial wall of the outer cup around the outer cup is formed with annular and separation piece, positioned at the annular and separation piece and institute State the cavity between the inner bottom wall of outer cup and form the reagent chamber, the inner side of the annular and separation piece forms opening for the reagent chamber Mouthful.
7. lyophilized reaction vessel according to claim 1, it is characterised in that the reagent chamber is one, positioned at described outer At the bottom centre position of cup.
8. lyophilized reaction vessel according to claim 1, it is characterised in that the opening of the reagent chamber and the outer cup Inclined-plane is formed between madial wall.
9. lyophilized reaction vessel according to claim 1, it is characterised in that the bottom peripheral edge of the interior cup is provided with oblique Angle.
10. lyophilized reaction vessel according to claim 1, it is characterised in that the rim of a cup of the interior cup and the outer cup Rim of a cup is detachable connection.
CN201710338292.3A 2017-05-15 2017-05-15 A kind of freeze-drying reaction vessel Active CN107014667B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710338292.3A CN107014667B (en) 2017-05-15 2017-05-15 A kind of freeze-drying reaction vessel

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Application Number Priority Date Filing Date Title
CN201710338292.3A CN107014667B (en) 2017-05-15 2017-05-15 A kind of freeze-drying reaction vessel

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CN107014667A true CN107014667A (en) 2017-08-04
CN107014667B CN107014667B (en) 2018-08-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110068673A (en) * 2019-06-04 2019-07-30 深圳麦科田生物医疗技术有限公司 Reaction vessel

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458941A (en) * 1968-03-13 1969-08-05 Pillsbury Co Freeze drying apparatus and process
US4561191A (en) * 1985-05-28 1985-12-31 Parkinson Martin C Method and apparatus for continuous freeze drying
CN2206262Y (en) * 1994-10-06 1995-08-30 桂林市医疗电子仪器厂 Reagent packaging container
CN2875227Y (en) * 2006-03-17 2007-03-07 张永东 Double mouth type core-warm cup
CN200942340Y (en) * 2006-08-03 2007-09-05 赵瑾明 Bushing type closed tube
CN204862377U (en) * 2015-04-13 2015-12-16 宁波宝斯迈婴童用品有限公司 Multi -functional alternating temperature cup

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458941A (en) * 1968-03-13 1969-08-05 Pillsbury Co Freeze drying apparatus and process
US4561191A (en) * 1985-05-28 1985-12-31 Parkinson Martin C Method and apparatus for continuous freeze drying
CN2206262Y (en) * 1994-10-06 1995-08-30 桂林市医疗电子仪器厂 Reagent packaging container
CN2875227Y (en) * 2006-03-17 2007-03-07 张永东 Double mouth type core-warm cup
CN200942340Y (en) * 2006-08-03 2007-09-05 赵瑾明 Bushing type closed tube
CN204862377U (en) * 2015-04-13 2015-12-16 宁波宝斯迈婴童用品有限公司 Multi -functional alternating temperature cup

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110068673A (en) * 2019-06-04 2019-07-30 深圳麦科田生物医疗技术有限公司 Reaction vessel

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Address after: 518000 12th floor, building 1, Baiwang R & D building, 5158 xilishahe West Road, Nanshan District, Shenzhen City, Guangdong Province

Patentee after: Shenzhen maiketian Biomedical Technology Co.,Ltd.

Address before: 518000 12th floor, building 1, Baiwang R & D building, 5158 xilishahe West Road, Nanshan District, Shenzhen City, Guangdong Province

Patentee before: Medcaptain Medical Technology Co.,Ltd.

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