CN1070108A - The prescription and the compound method thereof of finger, toenail ringworm paste - Google Patents

Abstract

The present invention relates to that a kind of treatment refers to, the manufacture method of toenail ringworm paste; an amount of by 50% salicylic acid 0.146g, 12% benzoic acid 0.002g, liquefied phenol 0.0032g, paraffin 0.004g, carmine 0.0004g, Diluted Alcohol, vaseline 0.0444g is molten and the corning flake drug; every weight is that 0.2g is placed in the medicine hole with the protective lining of silicone rubber system; stick on the centre position of adhered layer, be provided with protecting film above.This cream is to have to continue to discharge the long-acting tinea unguium bacterium of killing, and make efficacy of a drug height be penetrated into characteristic in the disease deck, make that horny layer is soft to be peeled off, and the adhered layer that can directly be fixed to the tinea unguium affected part makes medicine directly contact the increase curative effect with sick first, no pain, cure rate is more than 98%.

Description

The prescription and the compound method thereof of finger, toenail ringworm paste

The present invention relates to a kind of finger of fingernail, toenail tinea, the prescription and compound method thereof of toenail ringworm paste for the treatment of.

Medical department is to adopting antifungal agent griseofulvin for oral administration usually on finger, the toenail tinea patient treatment at present; Or refer to trouble, be coated with tinea unguium liquid medicine outside the deck of toenail tinea, econazole, the zinci undecylenatis compositum tinea liquid, compounding method (open day 1989126) as a CN1037844A tinea curing medicine water, CN1031798A suppresses the manufacture method (open day 1989322) of fungus tinea liquid, GK85104517 treatment foot, tinea manuum liquid medicine (open day 1987128) or whitfield ointment, compound acidi salicylici unguentum is treated, but it is long the sick course of treatment to adopt antifungal drug for oral administration to treat tinea unguium, can have side effects to health as taking for a long time, curative effect is not remarkable, be coated with tinea liquid or control tinea ointment also remarkable inadequately as employing to the sick curative effect of tinea unguium, also inconvenient in the use, more there be not a kind of can being fixed on to suffer from the sick first of tinea unguium, energy continues to discharge effective efficacy of a drug and long-acting brute force is killed the tinea unguium bacterium, and the porous deck refers to the soft treatment easy to use of stripping off of horny layer, the pharmaceutical formulation of toenail tinea and compound method.

The objective of the invention is to society provide a kind of to refer to, the toenail tinea has and continues to discharge effective efficacy of a drug and long-acting brute force and kill the tinea unguium bacterium, and can high infiltrate through the disease deck and make that the soft treatment of stripping off of horny layer refers to, finger, toenail ringworm paste and the compound method of toenail tinea.This refers to, toenail ringworm paste be provided with can protect refer to, toenail surrounding skin tissue; the centre is provided with the protective lining of putting medicine medicine hole and can be at the fixed adhered layer in the sick first place of tinea unguium; guaranteed that like this medicine closely contacts with trouble tinea first place; make drug effect permeate the disease deck; fully improved curative effect, and brought convenience for the patient in the use.

The present invention is achieved in that and has adopted simple and easy method of manufacturing technology; to have and to continue to discharge and long-acting brute force is killed the tinea unguium fungus; pitting; peel off cuticular medicine salicylic acid; sterilization anti-infectives liquefied phenol; the coloring agent carmine; Diluted Alcohol; substrate excipient paraffin and vaseline measure by a certain percentage successively mix fully grind and or molten and; make the medicine of wanting required for the present invention; be grain slice medicine grain through extrusion molding again; then the grain slice medicine being inserted protection refers to; putting in the medicine hole of the protective lining of toenail surrounding skin tissue, the centre position and the adhered layer formation that stick on adhered layer can be at the fixed fingers in fingernail toenail tinea affected part; toenail ringworm paste.Adhered layer is the non-toxic plastic film of the single face coating viscosity glue agent of the commonly used medical fabricbase rubber blanket of strip or strip, and the situation that they constitute is such; Adhered layer (1) scribbles the carcass of adhesive for strip; place in protective lining (2) medicine hole is being pasted in the centre position of adhered layer (1) length that treatment refers to, the medicine (3) of toenail tinea, at last the adhesive portion of mucilage glue surface two transverse planes of adhered layer (1) cover put two block lengths for this adhered layer (1) 2/3, width and adhered layer (1) put medicine (3) in the medicine hole with wide plastic protective film for plastics (4), (5) with the viscosity of the two ends gluing part of protection adhered layer (1) and protective lining (2) and unlikelyly be subjected to pollution, come off and drug effect is waved diffusing.

Concrete structure of the present invention is provided by following examples and accompanying drawing.

Fig. 1 is the finger that proposes of the present invention, the structural representation of toenail ringworm paste.

Fig. 2 is finger, the toenail ringworm paste structure cutaway view that the present invention proposes.

Finger of the present invention, toenail ringworm paste as shown in Figure 1, adhered layer (1) is general commonly used medical fabricbase adhesive plaster or non-toxic plastic film single spreading, the harmless adhesive of reply health, the adhered layer of strip.Pasting one in the centre position of adhered layer (1) length and be used for that protection refers to, toenail surrounding skin tissue, it is that employing is made health harmless spongy white silicone rubber or spongy white nontoxic rubber that the centre is provided with the protective lining (2) of putting the medicine hole.Be the finger of putting grain slice in the medicine hole of protective lining (2); toenail ringworm paste medicine (3) is preferably 0.146g by 50% salicylic acid 0.144g～0.148g(); 12% benzoic acid 0.001g～0.003g(is preferably 0.002g); liquefied phenol 0.0032g; paraffin 0.004g; carmine 0.0004g; Diluted Alcohol is an amount of; vaseline 0.0444g; employing is ground with method or fusion method and is made medicine; through extrusion molding; weight is the grain slice medicine grain of 0.2 gram; cover in the adhesive portion of stickup face two transverse planes of adhered layer (1) at last that to put two block lengths are 2/3 of these adhered layers (1); the plastic protective film that width is identical with adhered layer (4); (5) put unlikely pollution of medicine (3) in the medicine hole with the viscosity of the stickup plane two end gluings part of protection adhered layer (1) and protective lining (2); come off and drug effect is waved diffusing; only need tear the plastic protective film (4) of two ends during use off; (5) again the grain slice on the adhered layer (1) is referred to; the medicine of toenail ringworm paste (3) is aimed at trouble tinea deck and is located closely to contact to paste to fix; just can make pharmaceutical efficacy be penetrated into the finger of suffering from tinea; kill the tinea unguium fungus in the nail plate; pitting is peeled off horny layer; reach and continue to discharge the long-acting efficacy of a drug and cure and refer to; the effect of toenail tinea; the present invention is that a kind of use is extremely convenient; have no side effect; the treatment of effect instant effect refers to; the specific ointment of toenail tinea; changed dressings once in 24 hours; only need to reach several times to kill the tinea unguium fungus; the disease first is stripped off; painless; ruddy new fingernail is complete with healthy day by day germinating, and cure rate can reach more than 98%.And stopped finger, toenail tinea bacterium alternately infect refer to, the consequence of nail plate, protected the fitness of fingernail.

Claims (1)

1; a kind of manufacturing refers to; the process of toenail ringworm paste; the constituent that it is characterized in that medicament is 50% salicylic acid 0.144g～0.148g (being preferably 0.146g); 12% benzoic acid 0.001g～0.003g (being preferably 0.002g); liquefied phenol 0.0032g; paraffin 0.004g; carmine 0.0004g; Diluted Alcohol is an amount of; vaseline 0.0444g; employing grind with method or fusion method fully mix grind and or molten and form; through extrusion molding is grain slice medicine (3); the centre position of adhered layer (1) length pasting one be used for the protection refer to; toenail surrounding skin tissue; it is to adopt harmless spongy white silicone rubber or nontoxic platinum sponge shape rubber to make that the centre is provided with the protective lining (2) of putting medicine (3) medicine hole, refers to; protective film (4) (5) is arranged on the stickup face of toenail ringworm paste.