CN107010586B - Desktop type is liquid moving device in batches - Google Patents
Desktop type is liquid moving device in batches Download PDFInfo
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- CN107010586B CN107010586B CN201710338085.8A CN201710338085A CN107010586B CN 107010586 B CN107010586 B CN 107010586B CN 201710338085 A CN201710338085 A CN 201710338085A CN 107010586 B CN107010586 B CN 107010586B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67D—DISPENSING, DELIVERING OR TRANSFERRING LIQUIDS, NOT OTHERWISE PROVIDED FOR
- B67D7/00—Apparatus or devices for transferring liquids from bulk storage containers or reservoirs into vehicles or into portable containers, e.g. for retail sale purposes
- B67D7/06—Details or accessories
- B67D7/58—Arrangements of pumps
- B67D7/62—Arrangements of pumps power operated
Abstract
The invention provides a desktop type batch liquid transfer device which comprises a frame, wherein the frame comprises a bottom plate, the upper surface of the bottom plate is provided with a first supporting plate and a partition plate, the two sides of the first supporting plate are respectively provided with a support, the upper end of the partition plate is fixed on the first supporting plate, the partition plate is provided with a collecting pipe, the bottom plate is provided with a tray moving module, and a tray frame for bearing a reagent bottle tray is arranged on the tray moving module; the upper end part of the first surface of the first supporting plate is provided with an up-down moving module, the up-down moving module is provided with a needle moving module with a needle group, and the needle group corresponds to the needle guide module arranged on the bottom plate; the upper end of the second surface of the first supporting plate is provided with a circuit board, the partition plate is further provided with a pump set module, the needle set is connected with the pump set module through a plurality of first liquid discharge pipes, the pump set module is connected with the collecting pipe through a plurality of second liquid discharge pipes, and the collecting pipe discharges waste liquid through a third liquid discharge pipe. Above-mentioned desktop type moves liquid device in batches small, can be in batches clear away remaining waste liquid in the reagent bottle, work efficiency is high.
Description
Technical Field
The invention relates to the field of mechanical equipment, in particular to a desktop type batch liquid-transferring device.
Background
In fields such as medical science, often can detect various reagents, detect the back, often can remain some waste liquids in the reagent bottle, do not have the equipment that is used for reagent bottle waste liquid treatment specially at present at home and abroad, all lean on artifical bare-handed waste liquid in the reagent bottle to pour into waste liquid treatment pond and handle basically. For a reagent bottle with a small caliber, the waste liquid in the bottle is difficult to completely pour out, and when some special liquid such as drugs exists in the bottle, a lawless person is likely to be taken a chance. Along with the increasing importance of people to health in recent years, the workload of reagent detection is more and more heavy, the manual treatment mode can bring extra workload to detection personnel, the working efficiency is low, and when the residual waste liquid in the reagent bottle is a harmful chemical reagent, the physical health of the detection personnel can be damaged.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a desktop type batch liquid-transferring device, which is convenient for removing the residual waste liquid in reagent bottles in batches so as to improve the working efficiency.
In order to achieve the purpose, the invention provides a desktop type batch liquid-transfering device, which comprises a frame, wherein the frame comprises a bottom plate, a first supporting plate, two supports and a partition plate are arranged on the upper surface of the bottom plate, the two supports are respectively arranged on two sides of the first supporting plate, the upper end of the partition plate is fixed on the first supporting plate, a collecting pipe is further arranged on the partition plate, a tray moving module is further arranged on the bottom plate, and a tray rack for bearing reagent bottle trays is arranged on the tray moving module; an up-down moving module is arranged at the upper end part of the first surface of the first supporting plate, a needle moving module is arranged on the up-down moving module, a needle group is arranged on the needle moving module, and the needle group corresponds to a needle guide module arranged on the bottom plate; the upper end of the second surface of the first supporting plate is provided with a circuit board, the partition plate is further provided with a pump set module, the needle set is connected with the pump set module through a plurality of first liquid discharge pipes, the pump set module is connected with the collecting pipe through a plurality of second liquid discharge pipes, and the collecting pipe discharges waste liquid through a third liquid discharge pipe.
Preferably, the tray moving module includes a fixing plate, one end of the fixing plate is fixed on the bottom plate through two second supporting plates, the other end of the fixing plate is fixed on the first supporting plate, a first stepping motor is fixed on the lower surface of the fixing plate, a first encoder is arranged at the lower end of the first stepping motor, a driving wheel is fixed on an output shaft of the first stepping motor, the driving wheel is connected with a driven wheel through a belt, the driven wheel is arranged on the fixing plate through a first mandrel, and a tension wheel is further arranged on the fixing plate; the below of fixed plate be equipped with the first slide rail that the fixed plate is connected, be used for fixing the slip table of tray rack through first slider with first slide rail is connected, the slip table is connected with belt splint, belt splint with the belt is connected still be equipped with first zero-bit sensor, first spacing sensor and reagent bottle tray sensor on the fixed plate, wherein first zero-bit sensor is close to the action wheel, and first spacing sensor is close to from the driving wheel still be equipped with first response piece on the belt splint, first response piece is used for triggering first zero-bit sensor and first spacing sensor.
Preferably, the tray frame comprises a tray frame bottom plate, the tray frame bottom plate is fixed on the sliding table, and an angle code for fixing the reagent bottle tray is further arranged on the tray frame bottom plate; tray frame bottom plate's upper surface still is equipped with washs the box, it is equipped with the washing lid to wash the box upper end, it is equipped with a plurality of through-holes to wash box lid upper surface, and level sensor sets up via the fixing base wash on the box, the one end setting of first feed liquor pipe is in wash the box, its other end is connected with fourth step motor, fourth step motor sets up the lower tip on the second surface of first backup pad, with second feed liquor pipe that fourth step motor is connected with external washing liquid device.
Preferably, a plurality of grooves for containing reagent bottles are arranged on the reagent bottle tray, and the grooves are arranged in the reagent bottle tray in an array manner.
Preferably, the up-down moving module comprises a second stepping motor fixing plate, a first screw rod seat and a second screw rod seat which are sequentially arranged on the first supporting plate from top to bottom, a second sliding rail is arranged on the first supporting plate between the first screw rod seat and the second screw rod seat, the second stepping motor is fixed on the second stepping motor fixing plate, the first screw rod is positioned through the first screw rod seat and the second screw rod seat, the upper end of the first screw rod is connected with an output shaft of the second stepping motor through a coupler, the lower end of the first screw rod is connected with a second encoder, a first screw rod fixing piece with internal threads is arranged on the first screw rod between the first screw rod seat and the second screw rod seat, the first screw rod fixing piece is fixedly connected with the screw rod connecting seat, and a second sliding block matched with the second sliding rail is arranged on the screw rod connecting seat; second zero-bit sensor and the spacing sensor of second set up from top to bottom via the inductive switch fixed plate respectively on the first backup pad be equipped with the second response piece on the lead screw connecting seat, the second response piece is used for triggering second zero-bit sensor and the spacing sensor of second still be equipped with the ya keli row who is used for guiding the first drainpipe trend and press from both sides in the first backup pad.
Preferably, the needle moving module comprises a first needle group connecting plate fixed on the screw rod connecting seat, a third step motor fixing plate is arranged at the upper end of the first needle group connecting plate, a second needle group connecting plate perpendicular to the first needle group connecting plate is arranged at the lower end of the first needle group connecting plate, a third slide rail is arranged on the first needle group connecting plate between the third step motor fixing plate and the second needle group connecting plate, a third step motor is fixed on the third step motor fixing plate, a second screw rod fixing plate with internal threads is arranged on an output shaft of the third step motor, the second screw rod fixing plate is connected with a screw rod fixing seat, a third slide block matched with the third slide rail is arranged on the screw rod fixing seat, a needle seat is further arranged on the screw rod fixing seat, and a plurality of second through holes are formed in the needle seat; the other end of the output shaft of the third step motor is positioned by a second needle group connecting plate, the second needle group connecting plate is also connected with a needle group transition plate, the needle group transition plate is vertical to the second needle group connecting plate, the needle group transition plate is also connected with a needle group mounting plate, the needle group mounting plate is parallel to the needle head seat, the needle group mounting plate is provided with third through holes with the number equal to that of the second through holes, and the third through holes correspond to the second through holes one to one; third zero-bit sensor and the spacing sensor of third set gradually from top to bottom the both sides of first needle group connecting plate be equipped with third response piece and fourth response piece on the lead screw fixing base respectively, wherein the third response piece is used for triggering third zero-bit sensor, the fourth response piece is used for triggering the spacing sensor of third still be equipped with the ya keli clip that is used for guiding the first drain pipe trend on the lead screw fixing base.
Preferably, the needle group comprises a plurality of needle slide bars, the number of the needle slide bars is equal to that of the second through holes, each needle slide bar is correspondingly arranged in each second through hole on the needle head seat and is fixed by a clamp spring, the upper end of each needle slide bar is connected with the first liquid discharge pipe, the lower end of each needle slide bar is connected with the liquid extracting needle through a luer head, and a spring is sleeved on the needle slide bar above the luer head; the needle group also comprises a plurality of puncture needles, the number of the puncture needles is equal to that of the third through holes, and each puncture needle is correspondingly fixed in each third through hole on the needle group mounting plate; the aperture of the puncture needle is larger than that of the liquid drawing needle.
Preferably, the needle guide module includes that two needles fixed respectively on the bottom plate lead the backup pad fixedly connected with needle baffle in the needle guide backup pad, the needle baffle sets up in the top of tray frame and the below of needle group's mounting panel be equipped with a plurality of first through-holes on the needle baffle, the number of first through-hole is the same with the number of third through-hole, and each first through-hole and each third through-hole one-to-one still are equipped with the needle in every first through-hole and lead, the needle is led and is fixed by the jump ring, the needle is led and is offered hourglass hopper-shaped hollow cylinder for inside.
Preferably, the pump unit module comprises a pump unit mounting plate fixed on the partition plate, at least one pump fixing plate is arranged on the pump unit mounting plate, a plurality of peristaltic pumps are arranged on each pump fixing plate, and each peristaltic pump is connected with the collecting pipe through a plurality of second liquid discharge pipes.
Preferably, the circuit board comprises a controller, the controller is respectively connected with a voltage stabilizing module, a signal acquisition module, a driving module and a system state indicating module, the voltage stabilizing module is also connected with a power supply, the signal acquisition module is connected with sensors and encoders, and the sensors comprise a first zero position sensor, a first limit sensor, a reagent bottle tray sensor, a liquid level sensor, a second zero position sensor, a second limit sensor, a third zero position sensor and a third limit sensor; each path of encoder comprises a first encoder and a second encoder; the driving module respectively drives the first stepping motor, the second stepping motor, the third stepping motor, the fourth stepping motor and the peristaltic pump to act, and the system state indicating module is respectively connected with the indicating lamp and the buzzer.
The desktop type batch liquid-transfering device has the advantages that the desktop type batch liquid-transfering device is small in size, can be used for removing residual waste liquid in reagent bottles in batches, is high in working efficiency, separates puncture from a liquid-transfering task through the structural design of the two layers of needles, and can effectively prevent the blocking problem of the liquid-transfering needles.
Drawings
Fig. 1 shows a schematic view of a table-top batch pipetting device according to the invention.
Fig. 2 shows a schematic structural diagram of a framework according to the invention.
Fig. 3 shows a schematic structural view of a tray moving module according to the present invention.
Fig. 4 shows a schematic structural view of a tray rack according to the present invention.
Fig. 5 is a schematic view showing a structure of a reagent bottle tray according to the present invention.
Fig. 6 is a schematic structural view of the up-down moving module according to the present invention.
Fig. 7 shows a schematic structural diagram of a routing module according to the present invention.
Fig. 8 shows a schematic structural view of a needle set according to the present invention.
Figure 9 shows a schematic structural view of a pump group module according to the invention.
Fig. 10 shows a functional block diagram of a circuit board according to the present invention.
Reference numerals: 1-frame, 2-tray moving module, 3-tray rack, 4-cleaning box, 5-reagent bottle tray, 6-needle guide module, 7-up-down moving module, 8-needle moving module, 9-needle group, 10-pump group module, 11-fourth stepping motor, 12-circuit board, 13-acrylic clamp, 101-first bottom plate, 102-second bottom plate, 103-foot pad, 104-first support plate, 105-support, 106-partition plate, 107-manifold, 21-fixing plate, 22-second support plate, 23-first stepping motor, 24-first encoder, 25-driving wheel, 26-belt, 27-driven wheel, 28-tension wheel, 29-first slide rail, 210-first slide block, 211-slide table, 212-belt clamping plate, 213-first induction sheet, 214-first zero position sensor, 215-first limit sensor, 216-reagent bottle tray sensor, 217-lower pipe groove, 31-tray frame bottom plate, 32-corner code, 33-upper pipe groove, 34-clamping pipe, 41-cleaning box cover, 42-fixing seat, 43-liquid level sensor, 51-groove, 61-needle guide supporting plate, 62-needle guide plate, 63-first through hole, 64-needle guide, 71-second step motor fixing plate, 72-first screw rod seat, 73-second screw rod seat, 74-second step motor, 75-first screw rod, 76-coupler, 77-second encoder and 78-first screw rod fixing plate, 79-screw rod connecting seat, 710-second induction sheet, 711-second zero position sensor, 712-second limit sensor, 713-induction switch fixing plate, 714-second sliding block, 715-second sliding rail, 81-third stepping motor fixing plate, 82-third stepping motor, 83-second screw rod fixing plate, 84-screw rod fixing seat, 85-third induction sheet, 86-third zero position sensor, 87-third limit sensor, 88-fourth induction sheet, 89-fourth induction sheet support, 810-first needle group connecting plate, 811-second needle group connecting plate, 813-third sliding rail, 813-needle group transition plate, 814-needle group mounting plate, 815-needle head seat, 816-second through hole, 817-third through hole, 91-needle sliding rod, 92-peristaltic head, 93-liquid pumping needle, 94-spring, 95-puncture needle, pump group mounting plate, 1002-pump fixing plate, 1003-1001-second liquid discharge pipe, 121-power supply, 122-pressure stabilizer module, 123-voltage stabilizer module, 125-light acquisition module, 124-second liquid discharge pipe, 125-buzzer driving module and buzzer driving module.
Detailed Description
The following further describes embodiments of the present invention with reference to the drawings.
As shown in fig. 1, the desktop-type batch liquid-transferring apparatus according to the present invention includes a frame 1, the frame 1 includes a bottom plate, in this embodiment, the bottom plate includes a first bottom plate 101 and a second bottom plate 102, a foot rest 103 is provided on a lower surface of the first bottom plate 101, the second bottom plate 102 and a partition 106 are provided on an upper surface of the first bottom plate 101, a first support plate 104 and two supports 105 are provided on an upper surface of the second bottom plate 102, the two supports 105 are respectively provided on both sides of the first support plate 104, an upper end of the partition 106 is fixed to the first support plate 104, and a manifold 107 is further provided on the partition 106, as shown in fig. 2. Still be equipped with tray moving module 2 on the second bottom plate 102, the tray frame 3 that bears reagent bottle tray 5 sets up on the tray moving module 2, still be equipped with on the tray frame 3 and wash box 4, the one end setting of first feed liquor pipe (not shown in the figure) is in wash the box 4, and its other end is connected with fourth step motor 11, fourth step motor 11 sets up the lower tip on the second surface of first backup pad 104, the second feed liquor pipe (not shown in the figure) that is connected with fourth step motor 11 is connected with external washing liquid device. An up-down moving module 7 is arranged at the upper end of the first surface of the first supporting plate 104, a needle moving module 8 is arranged on the up-down moving module 7, a needle group 9 is arranged on the needle moving module 8, and the needle group 9 corresponds to the needle guide module 6 arranged on the second bottom plate 102. The circuit board 12 is disposed at the upper end of the second surface of the first support plate 104, the pump module 10 is disposed on the partition plate 106, the needle set 9 is connected to the pump module 10 through a plurality of first liquid discharge pipes (not shown), the pump module 10 is connected to the collecting pipe 107 through a plurality of second liquid discharge pipes (not shown), and the collecting pipe 107 discharges waste liquid through a third liquid discharge pipe (not shown).
As shown in fig. 3, the tray moving module 2 includes a fixing plate 21, one end of the fixing plate 21 is fixed to the second base plate 102 through two second supporting plates 22, the other end of the fixing plate 21 is fixed to the first supporting plate 104, a first stepping motor 23 is fixed to a lower surface of the fixing plate 21, a first encoder 24 is disposed at a lower end of the first stepping motor 23, a driving wheel 25 is fixed to an output shaft of the first stepping motor 23, the driving wheel 25 is connected to a driven wheel 27 through a belt 26, the driven wheel 27 is disposed on the fixing plate 21 through a first spindle (not shown), and a tension wheel 28 is further disposed on the fixing plate 21 for adjusting a tension of the belt 26. A first slide rail 29 connected with the fixed plate 21 is arranged below the fixed plate 21, a sliding table 211 is connected with the first slide rail 29 through a first slide block 210, and the sliding table 211 is used for fixing the tray frame 3. Slip table 211 is connected with belt splint 212, belt splint 212 with belt 26 is connected the upper surface of fixed plate 21 still is equipped with down groove pipe 217 to be used for guiding first feed liquor pipe still be equipped with first zero-bit sensor 214, first spacing sensor 215 and reagent bottle tray sensor 216 on the fixed plate 21, wherein first zero-bit sensor 214 is close to action wheel 25, and first spacing sensor 215 is close to from driving wheel 27 still be equipped with first response piece 213 on the belt splint 212, first response piece 213 is used for triggering first zero-bit sensor 214 and first spacing sensor 215.
As shown in fig. 4, the tray frame 3 includes a tray frame bottom plate 31, the tray frame bottom plate 31 is fixed on the sliding table 211, an angle code 32 for fixing the reagent bottle tray 5 is further provided on the tray frame bottom plate 31, and an upper pipe groove 33 and a clamping pipe 34 are further provided on the lower surface of the tray frame bottom plate 31 for guiding the first liquid inlet pipe. Tray frame bottom plate 31's upper surface is equipped with washs box 4, 4 upper ends of washing box are equipped with washs lid 41, it is used for preventing volatilizing of washing liquid to wash lid 41, it is equipped with a plurality of through-holes to wash lid 41 upper surface, and level sensor 43 sets up via fixing base 42 on the washing box 4 for detect the liquid level in the washing box 4.
As shown in fig. 5, a plurality of grooves 51 for accommodating reagent bottles are formed on the reagent bottle tray 5, and the plurality of grooves 51 are arranged in the reagent bottle tray 5 in an array. In order to discharge residual waste liquid in the reagent bottle, the bottom surface of each groove 51 is inclined by 10 to 15 degrees relative to the horizontal plane, so that the reagent bottle is placed in the reagent bottle tray 5 in an inclined manner.
As shown in fig. 6, the up-and-down moving module 7 includes a second stepping motor fixing plate 71, a first screw seat 72, and a second screw seat 73, which are sequentially disposed on the first support plate 104 from top to bottom, a second slide rail 715 is disposed on the first support plate 104 between the first screw seat 72 and the second screw seat 73, the second stepping motor 74 is fixed on the second stepping motor fixing plate 71, the first screw 75 is positioned by the first screw seat 72 and the second screw seat 73, the upper end of the first screw 75 is connected to the output shaft of the second stepping motor 74 by a coupling 76, the lower end of the first screw 75 is connected to a second encoder 77, a first screw fixing plate 78 (with an internal thread) is disposed on the first screw 75 between the first screw seat 72 and the second screw seat 73, the first screw fixing plate 78 is fixedly connected to a screw connecting seat 79, and a second slider 714 that is disposed on the screw connecting seat 79 and is used in cooperation with the second slide rail 715 is disposed on the screw connecting seat 79; second zero position sensor 711 and second spacing sensor 712 set up from top to bottom via inductive switch fixed plate 713 respectively on first backup pad 104 be equipped with second response piece 710 on the lead screw connecting seat 79, second response piece 710 is used for triggering second zero position sensor 711 and second spacing sensor 712 still be equipped with the ya keli that is used for guiding the first drain pipe trend on the first backup pad 104 and arrange the clamp 13.
As shown in fig. 7, the needle moving module 8 includes a first needle group connecting plate 810 fixed on the screw rod connecting seat 79, so that the needle moving module 8 can move up and down under the driving of the screw rod connecting seat 79; a third stepping motor fixing plate 81 is arranged at the upper end of the first needle group connecting plate 810, a second needle group connecting plate 811 perpendicular to the first needle group connecting plate 810 is arranged at the lower end of the first needle group connecting plate 810, a third sliding rail 812 is arranged on the first needle group connecting plate 810 between the third stepping motor fixing plate 81 and the second needle group connecting plate 811, the third stepping motor 82 is fixed on the third stepping motor fixing plate 81, a second lead screw fixing plate 83 (with internal threads) is arranged on an output shaft of the third stepping motor 82, the second lead screw fixing plate 83 is connected with a lead screw fixing seat 84, a third sliding block (not shown) matched with the third sliding rail 812 is arranged on the lead screw fixing seat 84, a needle seat 815 is further arranged on the lead screw fixing seat 84, and a plurality of second through holes 816 are arranged on the needle seat 815; the other end of the output shaft of the third step-in motor 82 is positioned by a second needle group connecting plate 811, the second needle group connecting plate 811 is further connected with a needle group transition plate 813, the needle group transition plate 813 is perpendicular to the second needle group connecting plate 811, the needle group transition plate 813 is further connected with a needle group mounting plate 814, the needle group mounting plate 814 is parallel to the needle head base 815, the needle group mounting plate 814 is provided with third through holes 817 the number of which is equal to that of the second through holes 816, and the third through holes 817 correspond to the second through holes 816 one by one; considering structural space's factor, third zero-position sensor 86 and third spacing sensor 87 set gradually from top to bottom the both sides of first needle group connecting plate 810 be equipped with third response piece 85 and fourth response piece 88 on the lead screw fixing base 84 respectively, wherein third response piece 85 is used for triggering third zero-position sensor 86, fourth response piece 88 is used for triggering third spacing sensor 87 can also be equipped with fourth response piece pillar 89 for more firm fixed fourth response piece 88, the one end of fourth response piece pillar 89 is fixed in on first needle group connecting plate 810, its other end with fourth response piece 88 is connected. The lead screw fixing seat 84 is further provided with an acrylic row clamp 13 for guiding the trend of the first drainage pipe.
As shown in fig. 8, the needle set 9 includes a plurality of needle slide bars 91, the number of the needle slide bars 91 is equal to the number of the second through holes 816, each needle slide bar 91 is correspondingly disposed in each second through hole 816 on the needle head base 815 and fixed by a clamp spring (not shown in the figure), the upper end of the needle slide bar 91 is connected with the first drainage tube, the lower end of the needle slide bar 91 is connected with the liquid extraction needle 93 through the luer head 92, and a spring 94 can be sleeved on the needle slide bar 91 above the luer head 92 for buffering effect; the needle set 9 further comprises a plurality of puncture needles 95, the number of the puncture needles 95 is equal to that of the third through holes 817, and each puncture needle 95 is correspondingly fixed in each third through hole 817 of the needle set mounting plate 814 in a threaded connection manner. The aperture of the puncture needle 95 is larger than that of the liquid extraction needle 93.
As shown in fig. 2, the needle guide module 6 includes two needle guide support plates 61 respectively fixed on the second bottom plate 102, a needle guide plate 62 is fixedly connected to the needle guide support plate 61, the needle guide plate 62 is disposed above the tray frame 3 and below the needle group mounting plate 814, a plurality of first through holes 63 are disposed on the needle guide plate 62, the number of the first through holes 63 is the same as that of the third through holes 817, each first through hole 63 corresponds to each third through hole 817 one by one, a needle guide 64 is further disposed in each first through hole 63, the needle guide 64 is fixed by a snap spring (not shown in the figure), and the needle guide 64 is a cylinder having a funnel-shaped hollow inside so as to limit the position where the puncture needle 95 punctures the reagent bottle cap, and to some extent, the deviation of the puncture position caused by the bending deformation of the puncture needle 95 can be corrected.
As shown in fig. 9, the pump unit module 10 includes a pump unit mounting plate 1001 fixed on the partition plate 106, a pump fixing plate 1002 is disposed on the pump unit mounting plate 1001, in order to save space, in this embodiment, an upper pump fixing plate 1002 and a lower pump fixing plate 1002 are disposed on the pump unit mounting plate 1001, a plurality of peristaltic pumps 1003 are disposed on each pump fixing plate 1002, and each peristaltic pump 1003 is connected to the collecting pipe 107 through a plurality of second liquid discharge pipes 1004.
As shown in fig. 10, the circuit board 12 includes a controller 123, in this embodiment, the controller 123 may adopt an ARM of STM32 series, the controller 123 is respectively connected to a voltage stabilizing module 122, a signal collecting module 124, a driving module 125 and a system status indicating module 126, the voltage stabilizing module 122 is further connected to a power supply 121, the signal collecting module 124 is connected to each sensor and each encoder, where each sensor includes a first zero sensor 214, a first limit sensor 215, a reagent bottle tray sensor 216, a liquid level sensor 43, a second zero sensor 711, a second limit sensor 712, a third zero sensor 86 and a third limit sensor 87; each path of encoder includes a first encoder 24 and a second encoder 77; the driving module 125 drives the first stepping motor 23, the second stepping motor 74, the third stepping motor 82, the fourth stepping motor 11 and the peristaltic pump 1003 to operate, and the system status indicating module 126 is connected to the indicator light 127 and the buzzer 128. The voltage regulator module 122, the signal acquisition module 124, the driver module 125 and the system status indicator module 126 are all functional modules commonly used in the prior art, and will not be described in detail herein.
In a specific using process, an initialization operation is first performed to drive the third stepping motor 82 to operate, so that the second lead screw fixing plate 83 drives the lead screw fixing seat 84 to move upward, and when the third sensing plate 85 triggers the third zero position sensor 86, the controller 123 stops the operation of the third stepping motor 82. Then, the second stepping motor 74 is driven to operate, so that the first lead screw fixing plate 78 drives the lead screw connecting seat 79 to move upward, and when the second sensing plate 710 triggers the second zero position sensor 711, the controller 123 stops the second stepping motor 74. Then, the first stepping motor 23 is driven to operate, so that the belt 26 drives the sliding table 211 to move, and when the first sensing piece 213 triggers the first zero sensor 214, the controller 123 stops the operation of the first stepping motor 23. Then, the first stepping motor 23 is driven to operate, the cleaning cartridge 4 is moved to a position below the needle guide 62, whether or not the cleaning liquid is present in the cleaning cartridge 4 is detected by the liquid level sensor 43, and if so, the initialization is completed. If not, cleaning liquid needs to be injected into the cleaning box 4, and in order to prevent false detection caused by failure of the liquid level sensor 43, the cleaning liquid possibly existing in the cleaning box 4 needs to be extracted, and the specific process is as follows: the second stepping motor 74 is driven to act, so that the first lead screw fixing piece 78 drives the lead screw connecting seat 79 to move downwards, and the puncture needle 95 is inserted into the cleaning box 4; the third stepping motor 82 is driven to act, so that the second lead screw fixing piece 83 drives the lead screw fixing seat 84 to move downwards, and the liquid extracting needle 93 is inserted into the bottom of the cleaning box 4; the peristaltic pump 1003 is driven to operate, and the liquid is drawn from the cleaning cartridge 4. Then, the third stepping motor 82 is driven to operate, the liquid drawing needle 93 is lifted, the second stepping motor 74 is driven to operate, and the puncture needle 95 is drawn out of the cleaning cartridge 4. And then, injecting a cleaning solution into the cleaning box 4 through the fourth stepping motor 11, detecting the liquid level height in the cleaning box 4 through the liquid level sensor 43, and when the preset liquid level height is reached, stopping the fourth stepping motor 11 by the controller 123, so that the initialization is finished.
The specific liquid extraction process is as follows: driving the first stepping motor 23 to move, so that the first row of grooves 51 of the reagent bottle tray 5 moves below the needle guide plate 62, and driving the second stepping motor 74 to move, so as to insert the puncture needle 95 into the reagent bottle; driving the third stepping motor 82 to act so as to insert the liquid extraction needle 93 into the bottom of the reagent bottle; the peristaltic pump 1003 is driven to operate, and the liquid is drawn from the reagent bottle. When the waste liquid is completely pumped out, the controller 123 stops the operation of the peristaltic pump 1003, drives the third stepping motor 82 to operate, lifts the liquid pumping needle 93, drives the second stepping motor 74 to operate, and pumps out the puncture needle 95. And then repeating the above actions to sequentially extract the waste liquid in the remaining rows of reagent bottles on the reagent bottle tray 5. Then, the first stepping motor 23 is driven to act, so that the cleaning box 4 moves to the lower part of the needle guide plate 62, and the second stepping motor 74 is driven to act, so that the puncture needle 95 is inserted into the cleaning box 4; driving the third stepping motor 82 to act so as to insert the liquid extraction needle 93 into the bottom of the cleaning box 4; the peristaltic pump 1003 is driven to operate, and the liquid suction needle 93 is cleaned. After the washing is completed, the controller 123 stops the operation of the peristaltic pump 1003, drives the third stepping motor 82 to operate, lifts the liquid extraction needle 93, drives the second stepping motor 74 to operate, and extracts the puncture needle 95. Then, the first stepping motor 23 is driven to operate, so that the first row of grooves 51 of the reagent bottle tray 5 moves to the lower side of the needle guide plate 62 to wait for the next round of drawing operation.
The desktop type batch liquid-transfering device is small in size, can remove residual waste liquid in reagent bottles in batches, is high in working efficiency, separates puncture from liquid-transfering task through the structural design of the two layers of needles, and can effectively prevent the blocking problem of the liquid-transfering needles.
Claims (6)
1. The utility model provides a desktop type is liquid-transfering device in batches which characterized in that: the reagent bottle tray rack comprises a frame, wherein the frame comprises a bottom plate, a first supporting plate, two supports and a partition plate are arranged on the upper surface of the bottom plate, the two supports are respectively arranged on two sides of the first supporting plate, the upper end of the partition plate is fixed on the first supporting plate, a collecting pipe is further arranged on the partition plate, a tray moving module is further arranged on the bottom plate, and a tray rack for bearing a reagent bottle tray is arranged on the tray moving module; an up-down moving module is arranged at the upper end part of the first surface of the first supporting plate, a needle moving module is arranged on the up-down moving module, a needle group is arranged on the needle moving module, and the needle group corresponds to a needle guide module arranged on the bottom plate; the upper end part of the second surface of the first supporting plate is provided with a circuit board, the partition plate is also provided with a pump set module, the needle set is connected with the pump set module through a plurality of first liquid discharge pipes, the pump set module is connected with the collecting pipe through a plurality of second liquid discharge pipes, and the collecting pipe discharges waste liquid through a third liquid discharge pipe;
the reagent bottle tray is provided with a plurality of grooves for containing reagent bottles, and the grooves are arranged in the reagent bottle tray in an array manner;
the up-down moving module comprises a second stepping motor fixing plate, a first lead screw seat and a second lead screw seat which are sequentially arranged on the first supporting plate from top to bottom, a second sliding rail is arranged on the first supporting plate between the first lead screw seat and the second lead screw seat, the second stepping motor is fixed on the second stepping motor fixing plate, a first lead screw is positioned through the first lead screw seat and the second lead screw seat, the upper end of the first lead screw is connected with an output shaft of the second stepping motor through a coupler, the lower end of the first lead screw is connected with a second encoder, a first lead screw fixing piece with internal threads is arranged on the first lead screw between the first lead screw seat and the second lead screw seat, the first lead screw fixing piece is fixedly connected with the lead screw connecting seat, and a second sliding block matched with the second sliding rail is arranged on the lead screw connecting seat; the second zero-position sensor and the second limit sensor are respectively arranged on the first supporting plate from top to bottom through the inductive switch fixing plate, a second induction sheet is arranged on the lead screw connecting seat and used for triggering the second zero-position sensor and the second limit sensor, and an acrylic clamp for guiding the direction of the first drainage pipe is further arranged on the first supporting plate;
the needle moving module comprises a first needle group connecting plate fixed on the screw rod connecting seat, a third stepping motor fixing plate is arranged at the upper end part of the first needle group connecting plate, a second needle group connecting plate vertical to the first needle group connecting plate is arranged at the lower end part of the first needle group connecting plate, a third sliding rail is arranged on the first needle group connecting plate between the third stepping motor fixing plate and the second needle group connecting plate, a third stepping motor is fixed on the third stepping motor fixing plate, a second screw rod fixing plate with internal threads is arranged on an output shaft of the third stepping motor, the second screw rod fixing plate is connected with a screw rod fixing seat, a third sliding block matched with the third sliding rail is arranged on the screw rod fixing seat, a needle seat is also arranged on the screw rod fixing seat, and a plurality of second through holes are formed in the needle seat; the other end of the output shaft of the third step motor is positioned by a second needle group connecting plate, the second needle group connecting plate is also connected with a needle group transition plate, the needle group transition plate is vertical to the second needle group connecting plate, the needle group transition plate is also connected with a needle group mounting plate, the needle group mounting plate is parallel to the needle head seat, the needle group mounting plate is provided with third through holes with the number equal to that of the second through holes, and the third through holes correspond to the second through holes one to one; a third zero-position sensor and a third limit sensor are sequentially arranged on two sides of the first needle group connecting plate from top to bottom, a third induction sheet and a fourth induction sheet are respectively arranged on the lead screw fixing seat, wherein the third induction sheet is used for triggering the third zero-position sensor, the fourth induction sheet is used for triggering the third limit sensor, and an acrylic clip row for guiding the trend of the first drainage pipe is also arranged on the lead screw fixing seat;
the needle group comprises a plurality of needle slide bars, the number of the needle slide bars is equal to that of the second through holes, each needle slide bar is correspondingly arranged in each second through hole on the needle head seat and is fixed by a clamp spring, the upper end of each needle slide bar is connected with the first liquid discharge pipe, the lower end of each needle slide bar is connected with the liquid extracting needle through the luer head, and the needle slide bar above the luer head is sleeved with a spring; the needle group also comprises a plurality of puncture needles, the number of the puncture needles is equal to that of the third through holes, and each puncture needle is correspondingly fixed in each third through hole on the needle group mounting plate; the aperture of the puncture needle is larger than that of the liquid drawing needle.
2. The desktop batch pipetting device of claim 1, wherein: the tray moving module comprises a fixed plate, one end of the fixed plate is fixed on the bottom plate through two second supporting plates, the other end of the fixed plate is fixed on the first supporting plate, a first stepping motor is fixed on the lower surface of the fixed plate, a first encoder is arranged at the lower end of the first stepping motor, a driving wheel is fixed on an output shaft of the first stepping motor, the driving wheel is connected with a driven wheel through a belt, the driven wheel is arranged on the fixed plate through a first mandrel, and a tensioning wheel is further arranged on the fixed plate; the below of fixed plate be equipped with the first slide rail that the fixed plate is connected, be used for fixing the slip table of tray rack through first slider with first slide rail is connected, the slip table is connected with belt splint, belt splint with the belt is connected still be equipped with first zero-bit sensor, first spacing sensor and reagent bottle tray sensor on the fixed plate, wherein first zero-bit sensor is close to the action wheel, and first spacing sensor is close to from the driving wheel still be equipped with first response piece on the belt splint, first response piece is used for triggering first zero-bit sensor and first spacing sensor.
3. The desktop batch pipetting device of claim 2, wherein: the tray frame comprises a tray frame bottom plate, the tray frame bottom plate is fixed on the sliding table, and an angle code for fixing the reagent bottle tray is further arranged on the tray frame bottom plate; tray frame bottom plate's upper surface still is equipped with washs the box, it is equipped with the washing lid to wash the box upper end, it is equipped with a plurality of through-holes to wash box lid upper surface, and level sensor sets up via the fixing base wash on the box, the one end setting of first feed liquor pipe is in wash the box, its other end is connected with fourth step motor, fourth step motor sets up the lower tip on the second surface of first backup pad, with second feed liquor pipe that fourth step motor is connected with external washing liquid device.
4. The desktop batch pipetting device of claim 2 or 3, wherein: the needle guide module comprises two needle guide supporting plates which are respectively fixed on the bottom plate, wherein a needle guide plate is fixedly connected to the needle guide supporting plates, the needle guide plate is arranged above the tray frame and below the needle group mounting plate, a plurality of first through holes are formed in the needle guide plate, the number of the first through holes is the same as that of the third through holes, the first through holes correspond to the third through holes one to one, a needle guide is further arranged in each first through hole, the needle guide is fixed by a clamp spring, and a funnel-shaped hollow cylinder is formed inside the needle guide.
5. The desktop batch pipetting device of claim 4, wherein: the pump unit module comprises a pump unit mounting plate fixed on the partition plate, at least one pump fixing plate is arranged on the pump unit mounting plate, a plurality of peristaltic pumps are arranged on each pump fixing plate, and each peristaltic pump is connected with the collecting pipe through a plurality of second liquid discharge pipes.
6. The desktop batch pipetting device of claim 5, wherein: the circuit board comprises a controller, the controller is respectively connected with a voltage stabilizing module, a signal acquisition module, a driving module and a system state indicating module, the voltage stabilizing module is also connected with a power supply, the signal acquisition module is connected with various sensors and various encoders, and each sensor comprises a first zero position sensor, a first limit sensor, a reagent bottle tray sensor, a liquid level sensor, a second zero position sensor, a second limit sensor, a third zero position sensor and a third limit sensor; each path of coder comprises a first coder and a second coder; the driving module respectively drives the first stepping motor, the second stepping motor, the third stepping motor, the fourth stepping motor and the peristaltic pump to act, and the system state indicating module is respectively connected with the indicating lamp and the buzzer.
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| CN115505486A (en) * | 2022-09-23 | 2022-12-23 | 广州湾区生物科技有限公司 | Move liquid module and nucleic acid extraction appearance |
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Denomination of invention: Desktop batch pipetting device Effective date of registration: 20230605 Granted publication date: 20221101 Pledgee: Industrial and Commercial Bank of China Limited Weihai Branch Pledgor: WEIHAI FURUI ROBOTICS CO.,LTD. Registration number: Y2023980042785 |
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