CN107007944A - The method for putting position is calibrated by human projection in a kind of radiotherapy operation - Google Patents
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Abstract
Description
技术领域technical field
本发明公开一种放疗手术中通过人体投影校准摆位的方法。The invention discloses a method for calibrating and positioning through human body projection in radiotherapy operation.
背景技术Background technique
放疗摆位就是物理师和操作人员通过移动治疗床和人体,将病人的肿瘤中心摆放到加速器等中心的过程。肿瘤中心是医生通过CT等医学影像确定的,治疗计划中的剂量计算、照射野设置都是以这个肿瘤中心为基准。加速器等中心是指加速器治疗中心,一台加速器安装好之后,它的等中心就是空间中确定的、唯一的点。放疗时,肿瘤中心如果与加速器等中心重合,病人就能得到最好的治疗效果。但是如果摆位不精确,肿瘤中心与加速器等中心之间就会存在偏差,放疗的时候正常的组织将会受到额外的照射,病变组织接受不到足够剂量的照射,导致肿瘤复发的概率大大增大。Radiotherapy positioning is the process in which physicists and operators place the patient's tumor center to the center of the accelerator by moving the treatment bed and the human body. The tumor center is determined by doctors through CT and other medical images, and the dose calculation and irradiation field setting in the treatment plan are all based on this tumor center. The accelerator isocenter refers to the accelerator treatment center. After an accelerator is installed, its isocenter is the determined and unique point in space. During radiotherapy, if the center of the tumor coincides with the center of the accelerator, the patient can get the best treatment effect. However, if the positioning is inaccurate, there will be deviations between the tumor center and the center of the accelerator. During radiotherapy, normal tissues will receive additional radiation, and diseased tissues will not receive sufficient doses of radiation, which will greatly increase the probability of tumor recurrence. big.
国内放疗摆位方案仍然以常规的X光和CT模拟定位为主。首先在定位室中,医生使用模拟定位机对病人体内肿瘤进行定位,具体过程如下:让病人躺在加速器床板上,用放疗定位膜将病人固定在床板上,然后扫描确定肿瘤中心,根据加速器机房的激光指示灯在放疗定位膜上做十字线标记。接着病人去治疗室接受放射治疗,定位室模拟机的机械参数、几何参数与治疗室的一样,所以如果病人躺在治疗室床板上的位置与在定位室里躺的位置一致,病人的肿瘤中心就能与加速器等中心重合。为了让病人躺的位置一致,医生会用放疗定位膜上的十字线对准机房的激光指示灯来进行摆位。Domestic radiotherapy positioning schemes are still based on conventional X-ray and CT simulation positioning. First, in the positioning room, the doctor uses a simulation positioning machine to locate the tumor in the patient's body. The specific process is as follows: let the patient lie on the accelerator bed, fix the patient on the bed with a radiotherapy positioning film, and then scan to determine the center of the tumor. The laser indicator light makes a cross-hair mark on the radiotherapy positioning film. Then the patient goes to the treatment room to receive radiation therapy. The mechanical parameters and geometric parameters of the simulator in the positioning room are the same as those in the treatment room. can coincide with the center of the accelerator. In order to make the patient lie in the same position, the doctor will use the crosshairs on the radiotherapy positioning film to align with the laser indicator light in the computer room for positioning.
实际上,在治疗室内病人躺的位置并不会那么准确,总会或多或少有偏差,这时使用放疗定位膜就会让膜变形,从而大大降低治疗效果。但是如果在使用放疗定位膜前先确认病人躺的位置合适,那么膜的变形就会在可以接受的范围内了。In fact, the patient's lying position in the treatment room is not so accurate, and there will always be more or less deviations. At this time, the use of radiotherapy positioning membranes will deform the membranes, thereby greatly reducing the treatment effect. However, if the patient's lying position is confirmed before using the radiotherapy positioning film, the deformation of the film will be within an acceptable range.
鉴于上述问题,有必要找到一种使用放疗定位膜前校准人体在床板上位置方法。In view of the above problems, it is necessary to find a method of calibrating the position of the human body on the bed before using the radiotherapy positioning film.
发明内容Contents of the invention
针对现有技术的不足,本发明解决的技术问题是校准人体在加速器床板上的位置,减小放疗定位膜的变形,提高放疗的质量。采用的方法是在治疗时使用放疗定位膜前,首先校准人体在床板上的位置。Aiming at the deficiencies of the prior art, the technical problem solved by the present invention is to calibrate the position of the human body on the accelerator bed, reduce the deformation of the radiotherapy positioning film, and improve the quality of radiotherapy. The method adopted is to first calibrate the position of the human body on the bed board before using the radiotherapy positioning film during treatment.
为解决上述技术问题,本发明的技术方案是这样实现的:In order to solve the problems of the technologies described above, the technical solution of the present invention is achieved in the following way:
本发明揭示了一种放疗手术中通过人体投影校准摆位的方法,包括以下步骤:The present invention discloses a method for calibrating positioning through human body projection in radiotherapy surgery, which includes the following steps:
B1:得到医学图像坐标系中人体体侧轮廓投影以及红外监控设备坐标系到医学图像坐标系的转换矩阵的步骤;B1: the step of obtaining the projection of the body profile in the medical image coordinate system and the conversion matrix from the infrared monitoring equipment coordinate system to the medical image coordinate system;
B2:得到红外监控设备坐标系中人体体侧轮廓的步骤;B2: the step of obtaining the body profile of the human body in the coordinate system of the infrared monitoring equipment;
B3:计算两坐标系下人体体侧轮廓投影的偏差以调整病人位置的步骤。B3: A step of calculating the deviation of the projection of the body contour of the human body under the two coordinate systems to adjust the position of the patient.
所述步骤B1包括以下步骤:S1:在定位室加速器床板上贴多个定位装置,对病人进行医学成像;S2:打开自主开发软件,导入病人的医学图像,对图像中的人体沿着垂直冠状面的方向做投影,投影记为A;S3:在软件中的图像中勾勒出定位装置,得到所有定位装置之间的相对位置关系;S4:在治疗室床板的同样位置固定与S1中同样数目的定位装置,打开红外监控设备;S5:红外监控设备追踪固定于床板上的定位装置的坐标并传输给计算机,计算机结合步骤S3中得到的定位装置间的位置关系,配准、计算得到红外监控设备坐标系与医学图像坐标系之间的转换矩阵。The step B1 includes the following steps: S1: paste a plurality of positioning devices on the accelerator bed of the positioning room, and perform medical imaging on the patient; S2: open the self-developed software, import the medical image of the patient, and scan the human body in the image along the vertical coronal The projection is made in the direction of the surface, and the projection is recorded as A; S3: Outline the positioning device in the image in the software to obtain the relative positional relationship between all positioning devices; S4: Fix the same number of positioning devices at the same position on the bed board in the treatment room as in S1 The positioning device, open the infrared monitoring equipment; S5: the infrared monitoring equipment tracks the coordinates of the positioning device fixed on the bed and transmits it to the computer, and the computer combines the positional relationship between the positioning devices obtained in step S3 to register and calculate the infrared monitoring Transformation matrix between device coordinate system and medical image coordinate system.
在本发明的至少一个实施例中,固定在定位室和治疗室床板上的定位装置的数量优选是三个以上,以保证检测到的定位装置的运动能够充分表现出三维空间中六个自由度(三维坐标系中三个方向上的平移和旋转)的变化。如果采用不足三个定位装置,会影响定位精度,甚至定位错误。一般会选择三个以上的定位装置,以免出现因为遮挡导致的定位失误。In at least one embodiment of the present invention, the number of positioning devices fixed on the positioning room and the treatment room bed is preferably more than three, so as to ensure that the detected motion of the positioning device can fully represent six degrees of freedom in three-dimensional space (translation and rotation in three directions in a three-dimensional coordinate system). If less than three positioning devices are used, the positioning accuracy will be affected, and even the positioning will be wrong. Generally, more than three positioning devices are selected to avoid positioning errors caused by occlusion.
在本发明的至少一个实施例中,所述定位装置是可被红外监控设备识别的红外定位小球,但是所述领域的技术人员无需创造性劳动,就应该想到采用其他具有明显红外特征的材质制成的其他形状标记物体代替所述的定位小球。因此类似的技术方案也没有超过本发明所公开并要求保护的范围。In at least one embodiment of the present invention, the positioning device is an infrared positioning ball that can be recognized by infrared monitoring equipment, but those skilled in the art should think of using other materials with obvious infrared characteristics Formed other shape marking objects to replace the positioning bead. Therefore, similar technical solutions do not exceed the scope disclosed and claimed by the present invention.
在本发明的至少一个实施例中,对图像中的人体沿着垂直冠状面的方向做投影是指将病人的体侧轮廓投影到床板上。In at least one embodiment of the present invention, projecting the human body in the image along the direction vertical to the coronal plane refers to projecting the patient's side profile onto the bed board.
在本发明的至少一个实施例中,所述红外监控设备能够识别所述定位装置并返回定位装置的实时坐标。红外监控设备是可以得到定位装置三维坐标的设备,但是所述领域的技术人员无需创造性劳动,就应该想到通过其他原理与途径得到定位装置坐标的设备。因此类似的技术方案也没有超过本发明所公开并要求保护的范围。In at least one embodiment of the present invention, the infrared monitoring device can identify the positioning device and return the real-time coordinates of the positioning device. Infrared monitoring equipment is a device that can obtain the three-dimensional coordinates of the positioning device, but those skilled in the art should think of equipment that obtains the coordinates of the positioning device through other principles and approaches without creative work. Therefore, similar technical solutions do not exceed the scope disclosed and claimed by the present invention.
所述步骤B2包括以下步骤:S6:让病人躺在治疗室床板上并根据体表十字线标记摆位;S7:用轮廓刷沿着人体的侧面竖直刷过,红外监控设备实时传送轮廓刷上定位装置的坐标给软件;S8:软件沿着垂直床板的方向对轮廓刷上定位装置的运动轨迹做投影,投影记为B;The step B2 includes the following steps: S6: Let the patient lie on the bed in the treatment room and position it according to the cross marks on the body surface; S7: Use the contour brush to brush vertically along the side of the human body, and the infrared monitoring device transmits the contour brush in real time The coordinates of the upper positioning device are given to the software; S8: The software projects the trajectory of the upper positioning device on the contour brush along the direction perpendicular to the bed board, and the projection is recorded as B;
在本发明的至少一个实施例中,所述轮廓刷是自主发明的,所述定位装置固定于轮廓刷的顶部,轮廓刷的中间是一条直杆,底部固定一个角度仪,角度仪显示的是直杆与水平方向所成的角度。所述定位装置是可被所述红外监控设备识别的红外定位小球,但是所述领域的技术人员无需创造性劳动,就应该想到采用其他具有明显红外特征的材质制成的其他形状标记物体代替所述的定位小球。因此类似的技术方案也没有超过本发明所公开并要求保护的范围。In at least one embodiment of the present invention, the contour brush is independently invented, the positioning device is fixed on the top of the contour brush, the middle of the contour brush is a straight rod, and an angle meter is fixed at the bottom, and the angle meter shows The angle formed by the straight bar with the horizontal. The positioning device is an infrared positioning ball that can be identified by the infrared monitoring equipment, but those skilled in the art should think of using other shaped marking objects made of other materials with obvious infrared characteristics to replace the The positioning ball described above. Therefore, similar technical solutions do not exceed the scope disclosed and claimed by the present invention.
所述步骤B3包括以下步骤:S9:计算机将S5计算得到的转换矩阵作用于投影B,使其转移到投影A的坐标系下,计算两个投影间的偏差并相应地调整病人的位置。S10:重复重复所述步骤S6~S9直至偏差处于一定的阈值内。The step B3 includes the following steps: S9: The computer applies the transformation matrix calculated in S5 to the projection B to transfer it to the coordinate system of the projection A, calculates the deviation between the two projections and adjusts the position of the patient accordingly. S10: Repeat steps S6-S9 until the deviation is within a certain threshold.
本发明的有益效果在于:可以校准人体在床板上的位置,减小放疗定位膜变形,从而提高放射治疗的质量。The beneficial effect of the invention is that the position of the human body on the bed can be calibrated, the deformation of the radiotherapy positioning film can be reduced, and the quality of radiotherapy can be improved.
附图说明Description of drawings
图1是本发明的流程示意图。Fig. 1 is a schematic flow chart of the present invention.
图2是本发明中使用的工具轮廓刷的示意图。Figure 2 is a schematic illustration of a tool contour brush used in the present invention.
图3是软件得到的结果示意图。Figure 3 is a schematic diagram of the results obtained by the software.
图4是应用场景示意图。Fig. 4 is a schematic diagram of an application scenario.
具体实施方式detailed description
为了使本发明的目的、技术方案和优点更加清楚,下面结合附图和具体实施例对本发明进行详细描述。In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.
参考图2,轮廓刷上的定位装置是可被红外监控设备识别的红外定位小球。红外定位小球表面覆盖一层能够反射绝大部分入射红外光线的材料。红外监控设备发射红外光被小球反射回来,红外监控设备接收反射回来的红外光线,分析数据计算得到小球的三维位置坐标,实现了监控定位装置的目的。Referring to Fig. 2, the positioning device on the contour brush is an infrared positioning ball that can be identified by an infrared monitoring device. The surface of the infrared positioning ball is covered with a layer of material that can reflect most of the incident infrared light. The infrared light emitted by the infrared monitoring equipment is reflected back by the small ball, and the infrared monitoring equipment receives the reflected infrared light, analyzes the data and calculates the three-dimensional position coordinates of the small ball, and realizes the purpose of monitoring and positioning the device.
参考图2,角度仪固定在直杆上,能够测试直杆与水平方向成的角度。在用轮廓刷测得人体侧轮廓时,保证角度仪的示数在90度。确保定位装置坐标在床板上的投影就是直杆与人体接触点坐标在床板上的投影。直杆底部是一块水平的底板,底板与直杆是垂直的,用于辅助直杆保持竖直状态。Referring to Figure 2, the goniometer is fixed on the straight rod, and can test the angle formed by the straight rod and the horizontal direction. When measuring the side profile of the human body with the profile brush, ensure that the reading of the goniometer is at 90 degrees. Ensure that the projection of the coordinates of the positioning device on the bed is exactly the projection of the coordinates of the contact point between the straight rod and the human body on the bed. The bottom of the straight rod is a horizontal base plate, and the base plate is vertical to the straight rod, which is used to assist the straight rod to maintain a vertical state.
参考图3,软件得到定位装置的轨迹坐标,对其做垂直床板方向的投影。与病人的医学解剖结构图像在垂直人体冠状面方向上的投影作比较,软件给出病人位置的调整方向与距离。Referring to Fig. 3, the software obtains the trajectory coordinates of the positioning device, and makes a projection in the direction perpendicular to the bed board. Compared with the projection of the patient's medical anatomical structure image in the direction perpendicular to the coronal plane of the human body, the software gives the adjustment direction and distance of the patient's position.
参考图4,本发明的具体过程如下:With reference to Fig. 4, concrete process of the present invention is as follows:
S1:在定位室加速器床板上固定多个定位装置,对病人进行医学成像;S1: Fix multiple positioning devices on the accelerator bed of the positioning room to perform medical imaging on the patient;
S2:打开自主开发软件,导入病人的医学图像,对图像中的人体沿着垂直冠状面的方向做投影,投影记为A;S2: Open the self-developed software, import the patient's medical image, and project the human body in the image along the direction of the vertical coronal plane, and record the projection as A;
S3:在软件中的图像中勾勒出定位装置,得到所有定位装置之间的相对位置关系;S3: Outline the positioning device in the image in the software to obtain the relative positional relationship between all positioning devices;
S4:在治疗室床板的同样位置固定与S1中同样数目的定位装置,打开红外监控设备;S4: Fix the same number of positioning devices as in S1 on the same position of the bed board in the treatment room, and turn on the infrared monitoring equipment;
S5:红外监控设备追踪固定于床板上的定位装置的坐标并传输给计算机,计算机结合步骤S3中得到的定位装置间的位置关系,配准、计算得到红外监控设备坐标系与医学图像坐标系之间的转换矩阵。S5: The infrared monitoring equipment tracks the coordinates of the positioning device fixed on the bed and transmits them to the computer. The computer combines the positional relationship between the positioning devices obtained in step S3 to register and calculate the coordinate system of the infrared monitoring equipment and the medical image coordinate system. transformation matrix between them.
S6:让病人躺在治疗室床板上并根据体表十字线标记摆位;S6: Let the patient lie on the bed in the treatment room and position it according to the cross marks on the body surface;
S7:用轮廓刷沿着人体的侧面竖直刷过,红外监控设备实时传送轮廓刷上定位装置的坐标给软件;S7: Use the contour brush to brush vertically along the side of the human body, and the infrared monitoring equipment transmits the coordinates of the positioning device on the contour brush to the software in real time;
S8:软件沿着垂直床板的方向对轮廓刷上定位装置的运动轨迹做投影,投影记为B;S8: The software projects the trajectory of the positioning device on the contour brush along the direction perpendicular to the bed board, and the projection is marked as B;
S9:计算机将S5计算得到的转换矩阵作用于投影B,使其转移到投影A的坐标系下,计算两个投影间的偏差并相应地调整病人的位置。S9: The computer applies the transformation matrix calculated in S5 to the projection B to transfer it to the coordinate system of the projection A, calculates the deviation between the two projections and adjusts the position of the patient accordingly.
S10:重复重复所述步骤S6~S9直至偏差处于一定的阈值内。S10: Repeat steps S6-S9 until the deviation is within a certain threshold.
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CN107510470A (en) * | 2017-09-30 | 2017-12-26 | 苏州众志医疗科技有限公司 | Positioner and localization method for medical imaging device |
CN108434612A (en) * | 2018-01-05 | 2018-08-24 | 沈阳东软医疗系统有限公司 | A kind of QAT quality assurance test method and device |
CN112675442A (en) * | 2020-12-30 | 2021-04-20 | 北京凯佰特科技股份有限公司 | Positioning system for boron neutron capture therapy |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN107510470A (en) * | 2017-09-30 | 2017-12-26 | 苏州众志医疗科技有限公司 | Positioner and localization method for medical imaging device |
CN108434612A (en) * | 2018-01-05 | 2018-08-24 | 沈阳东软医疗系统有限公司 | A kind of QAT quality assurance test method and device |
CN108434612B (en) * | 2018-01-05 | 2020-07-10 | 东软医疗系统股份有限公司 | Quality assurance testing method and device |
CN112675442A (en) * | 2020-12-30 | 2021-04-20 | 北京凯佰特科技股份有限公司 | Positioning system for boron neutron capture therapy |
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