CN112675442A - Positioning system for boron neutron capture therapy - Google Patents

Positioning system for boron neutron capture therapy Download PDF

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Publication number
CN112675442A
CN112675442A CN202011608140.9A CN202011608140A CN112675442A CN 112675442 A CN112675442 A CN 112675442A CN 202011608140 A CN202011608140 A CN 202011608140A CN 112675442 A CN112675442 A CN 112675442A
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CN
China
Prior art keywords
collimator
calibration device
lasers
neutron capture
capture therapy
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Pending
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CN202011608140.9A
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Chinese (zh)
Inventor
张紫竹
许文泽
刘彤
陈阳
王玲
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Beijing Capture Tech Co ltd
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Beijing Capture Tech Co ltd
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Priority to CN202011608140.9A priority Critical patent/CN112675442A/en
Publication of CN112675442A publication Critical patent/CN112675442A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a positioning system for boron neutron capture therapy, which comprises a positioning part and a positioning part, wherein the positioning part comprises a first group of lasers, a ray source simulator and a first calibration device, and 4 alignment lasers of the first group of lasers are respectively arranged in front of, on the left of, on the right of and vertically above the first calibration device; the swinging part comprises a second group of lasers, a treatment room collimator and a second calibration device, and 4 alignment lasers of the second group of lasers are respectively arranged in front of, on the left of, on the right of and vertically above a calibration block on the second calibration device. According to the invention, the two positioning parts and the positioning part with consistent positioning are arranged, so that a patient can be prepared in advance on the positioning parts before boron neutron capture therapy treatment, the body position adopted during treatment can be accurately determined, the time for preparing and adjusting the posture position of the patient in front of the collimator of the treatment room is shortened, and the utilization efficiency of the treatment room is improved.

Description

Positioning system for boron neutron capture therapy
Technical Field
The invention relates to an auxiliary tool used in boron neutron capture therapy, in particular to a positioning system for boron neutron capture therapy, which is mainly used for assisting medical staff to determine an irradiation part and repeated positioning before irradiation in the process of boron neutron capture therapy.
Background
Boron neutron capture therapy BNCT is a new technology for binary targeted radiotherapy of tumors. It is prepared by intravenous injection according to the specific absorption and concentration of tumor cells to certain boron-containing medicine10B is introduced into the tumor, and then the tumor site is irradiated with thermal neutrons to generate10B(n,α)7The Li nucleus reaction. The reaction product is high-energy alpha particles and7and Li ions. Their range is equal to the size of cells, so that it can kill cancer cells in situ without damaging or hardly damaging normal tissues around the tumor, so that it can attain the goal of curing tumor. BNCT is a local radiotherapy method and requires the location of the site to be irradiated to be determined before treatment to ensure accurate administration of the irradiation dose. A system is therefore needed to assist medical personnel in determining the fraction of irradiation and repositioning for the patient. The present invention has been made in view of the above circumstances.
Disclosure of Invention
The invention aims to provide a boron neutron capture therapy positioning system, which comprises a positioning part and a positioning part, wherein the positioning part comprises a first group of lasers, a ray source simulator and a first calibration device, the first calibration device is movably arranged in front of the ray source simulator, the height of a calibration block on the first calibration device is the same as that of a ray source simulation laser in the ray source simulator, and 4 alignment lasers of the first group of lasers are respectively arranged in front of, on the left, on the right and vertically above the first calibration device; the swinging part comprises a second group of lasers, a treatment room collimator and a second calibration device, the second calibration device is movably arranged in front of the treatment room collimator, the height of a calibration block on the second calibration device is the same as that of a ray outlet of the treatment room collimator, and the 4 alignment lasers of the second group of lasers are respectively arranged in front of, on the left side, on the right side and vertically above the calibration block on the second calibration device.
Furthermore, the first calibration device and the second calibration device have the same structure and both comprise a calibration block and a movable base, and the calibration block is arranged at the top of the upright rod on the movable base.
Furthermore, the ray source simulator comprises a simulator support, a simulation collimator and a ray source simulation laser, wherein the simulator support is a cuboid-shaped frame, the simulation collimator is arranged at the front part of the simulator support, and the ray source simulation laser is arranged at the rear part of the simulator support and at the same horizontal position as a central hole of the simulation collimator.
Furthermore, the simulation collimator is formed by transparent acrylic plastic suction, and the external dimension of the simulation collimator is consistent with that of the treatment room collimator.
Further, the alignment laser is arranged on the laser translation stage and can translate along the axial direction of the treatment room collimator.
Furthermore, the calibration block is a cube, and the other 5 surfaces except the bottom surface are all processed with cross lines.
Further, the calibration block is made of aluminum alloy.
Further, in the setup section, the laser in front of the treatment room collimator is a moving cross-line pointer comprising a cross-line laser pointer and a highly repetitive movable base, the cross-line laser pointer being arranged on top of the highly repetitive movable base.
Further, the positioning part and the positioning part are positioned in a consistent manner.
The invention has the beneficial effects that: by arranging the two positioning parts and the positioning part with consistent positioning, a patient can be prepared in advance on the positioning parts before boron neutron capture therapy treatment, the body position and the irradiation position adopted during treatment can be accurately determined, the time for preparing and adjusting the posture position of the patient in front of a collimator of a treatment room is shortened, and the utilization efficiency of the treatment room is improved.
Drawings
FIG. 1 is a schematic diagram of a positioning part structure of a boron neutron capture therapy positioning system.
FIG. 2 is a schematic structural diagram of a positioning part of the positioning system for boron neutron capture therapy.
FIG. 3 is a schematic structural diagram of a calibration device of the boron neutron capture therapy positioning system of the invention.
FIG. 4 is a schematic structural diagram of a radiation source simulator of the boron neutron capture therapy positioning system of the invention.
Fig. 5 is a schematic structural diagram of a combination of an alignment laser and a laser translation stage of the boron neutron capture therapy positioning system of the invention.
FIG. 6 is a schematic diagram of the mobile cross-hair indicator structure of the boron neutron capture therapy positioning system of the present invention.
Fig. 7 is a schematic structural diagram of an alignment laser of the boron neutron capture therapy positioning system of the invention.
The system comprises a positioning part 100, a positioning part 110, a first group of lasers, a 111-alignment laser, a 120-ray source simulator, a 121-simulator support, a 122-simulation collimator, a 123-ray source simulation laser, a 130-first calibration device, a 131-calibration block, a 132-movable base, a 133-vertical rod, a 140-laser translation table, a 200-positioning part, a 210-second group of lasers, a 211-alignment laser, a 210-treatment room collimator, a 230-second calibration device, a 231-calibration block, a 232-movable base, a 233-vertical rod, a 240-movable cross-line indicator, a 241-cross-line laser indicator, a 242-movable base and a 243-vertical rod.
Detailed Description
In the description of the present invention, it is to be understood that, unless otherwise specified, "a plurality" means two or more; the terms "central," "longitudinal," "lateral," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in an orientation or positional relationship indicated in the drawings for ease of description and simplicity of description, and do not indicate or imply that the referenced device or element must have a particular orientation, be constructed in a particular orientation, and be operated in a particular orientation, and are therefore not to be construed as limiting the scope of the present invention. Furthermore, the terms "first," "second," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood as appropriate to those of ordinary skill in the art.
As shown in fig. 1 and 2, a boron neutron capture therapy positioning system comprises a positioning part 100 and a positioning part 200, wherein the positioning part 100 comprises a first group of lasers 110, a radiation source simulator 120 and a first calibration device 130, the first calibration device 130 is movably arranged in front of the radiation source simulator 120, the height of a calibration block 131 on the first calibration device 130 is the same as that of a radiation source simulation laser 123 in the radiation source simulator 120, and 4 alignment lasers 111 of the first group of lasers 110 are respectively arranged in front of, to the left of, to the right of and vertically above the first calibration device 130; as shown in fig. 2, the positioning part 200 includes a second set of lasers 210, a treatment room collimator 220 and a second calibration device 230, the second calibration device 230 is movably disposed in front of the treatment room collimator 220, a height of a calibration block 231 on the second calibration device 230 is the same as a height of a ray exit of the treatment room collimator 220, and 4 alignment lasers 211 of the second set of lasers 210 are respectively disposed in front of, to the left of, to the right of, and vertically above the calibration block 231 on the second calibration device 230.
As shown in FIG. 3, the first calibration device 130 and the second calibration device 230 are identical in structure and both comprise a calibration block (131,231) and a movable base (132,232), and the calibration block (131,231) is arranged on the top of an upright (133,233) on the movable base (132, 232). The movable base (132,232) is a highly repeatable base having high repeatability.
The calibration blocks (131,231) are made of aluminum alloy, are in a cube shape as a whole and have six surfaces, and the other 5 surfaces except the bottom surface are all provided with cross lines for focusing and positioning of the alignment laser.
As shown in fig. 4, the radiation source simulator 120 includes a simulator support 121, a simulation collimator 122 and a radiation source simulation laser 123, the simulator support 121 is a rectangular frame, the simulation collimator 122 is disposed at the front of the simulator support 121, and the radiation source simulation laser 123 is disposed at the rear of the simulator support 121 and at the same horizontal position as the central hole of the simulation collimator 122.
The simulated collimator 122 is formed by transparent acrylic plastic, and the external dimension of the simulated collimator is consistent with that of the treatment room collimator 220.
As shown in fig. 5, the alignment laser (111,211) is disposed on the laser translation stage 140 and can be translated along the axial direction of the collimator 122, thereby completing the position adjustment of the alignment laser (111, 211). The laser translation stage 140 is calibrated to record the displacement of the alignment lasers (111,211) thereon.
As shown in fig. 2 and 6, in the positioning portion 200, the alignment laser in front of the treatment room collimator 220 is a moving cross-line pointer 240, which includes a cross-line laser pointer 241 and a highly repetitive movable base 242, the cross-line laser pointer 241 being disposed on top of an upright 243 on the highly repetitive movable base 242.
In one embodiment, as shown in FIG. 7, the alignment lasers (111,121) included in the first group of lasers 110 and the second group of lasers 210 are of the same type and size, and each is a laser having a pair of transverse and longitudinal beams, which has a manual trimming function with a linewidth of 1mm/3 m.
During the use process, the positioning part 100 and the positioning part 200 are positioned in the same way, that is, the mutual positions and parameter settings of the alignment lasers contained in the first group of lasers 110 and the second group of lasers 210 are the same, the position parameters of the radiation source simulator 120 and the treatment room collimator 220 are the same, and the position parameters of the first calibration device 130 and the second calibration device 230 are the same. In this way, the body part and the posture of the patient to be treated, which are adjusted in the simulation chamber, can be accurately reproduced in the treatment chamber.
In the present invention, the positioning system comprises a positioning part 100 located between the simulated positioning and a positioning part 200 located in the treatment room. The positioning part 100 has the main functions of assisting medical staff to help the patient to determine the direction and position of the radiation field before the treatment of the patient, marking, and placing, recording and repeating the position information of the patient for subsequent planning and treatment. In the specific operation, after the irradiation body position of the patient is determined, marking is carried out on the body surface of the patient according to the cross laser line prompt, lead shot marks are used at the cross intersection points, then CT scanning is carried out on the patient, the relative position relation between the beam and the patient is determined according to the lead shot position, and the position information of the patient is provided for dose calculation. The positioning part 200 has the main functions that before the treatment of the patient, medical staff is assisted to repeat the treatment body position determined by the patient during the positioning in the simulation positioning room, and the cross point mark on the front body surface of the patient and the cross laser line in the treatment room are utilized during the operation to ensure that the two are superposed as much as possible, thereby achieving the purpose of accurately reproducing the treatment body position of the patient.
It should be noted that, in the present invention, the alignment laser 111 and the alignment laser 121 are the same type of laser; the calibration block 131 and the calibration block 231 are cubes of the same shape, and the movable base 132, the movable base 232, and the movable base 242 are bases of the same shape; the upright 133, the upright 233 and the upright 243 are upright rods of the same shape and specification.
The above examples are only for illustrating the technical solutions of the present invention, and are not intended to limit the scope of the present invention. But all equivalent changes and modifications within the scope of the present invention should be considered as falling within the scope of the present invention.

Claims (9)

1. A boron neutron capture therapy positioning and positioning system comprises a positioning part (100) and a positioning part (200), and is characterized in that the positioning part (100) comprises a first group of lasers (110), a ray source simulator (120) and a first calibration device (130), the first calibration device (130) is movably arranged in front of the ray source simulator (120), the height of a calibration block (131) on the first calibration device (130) is the same as that of a ray source simulation laser (123) in the ray source simulator (120), and 4 alignment lasers (111) of the first group of lasers (110) are respectively arranged in front of, on the left side, on the right side and vertically above the first calibration device (130); the positioning part (200) comprises a second group of lasers (210), a treatment room collimator (220) and a second calibration device (230), the second calibration device (230) is movably arranged in front of the treatment room collimator (220), the height of a calibration block (231) on the second calibration device (230) is the same as that of a ray outlet of the treatment room collimator (220), and 4 alignment lasers (211) of the second group of lasers (210) are respectively arranged in front of, on the left side, on the right side and vertically above the calibration block (231) on the second calibration device (230).
2. The boron neutron capture therapy positioning system of claim 1, wherein the first calibration device (130) and the second calibration device (230) are identical in structure and each comprise a calibration block (131,231) and a movable base (132,232), and the calibration block (131,231) is arranged on the top of an upright (133,233) on the movable base (132, 232).
3. The boron neutron capture therapy positioning system according to claim 1, wherein the radiation source simulator (120) comprises a simulator support (121), a simulation collimator (122) and a radiation source simulation laser (123), the simulator support (121) is a rectangular frame, the simulation collimator (122) is arranged at the front part of the simulator support (121), and the radiation source simulation laser (123) is arranged at the rear part of the simulator support (121) and at the same horizontal position as the central hole of the simulation collimator (122).
4. The boron neutron capture therapy positioning system of claim 3, wherein the simulated collimator (122) is formed by transparent acrylic plastic molding and has an outer shape dimension consistent with that of the treatment room collimator (220).
5. The boron neutron capture therapy positioning system of claim 1, wherein the alignment laser (111,211) is disposed on a laser translation stage (140) capable of translating along an axial direction of a radiation source simulator (120) or a treatment room collimator (220).
6. The boron neutron capture therapy positioning system of claim 1, wherein the calibration block (131,231) is a cube, and 5 other faces except the bottom face are all cross-hatched.
7. The boron neutron capture therapy positioning system of claim 6, wherein the calibration block (131,231) is fabricated from an aluminum alloy.
8. The boron neutron capture therapy positioning system of any of claims 1 to 7, wherein the alignment laser in front of the treatment room collimator (220) in the positioning section (200) is a moving cross-line pointer (240) comprising a cross-line laser pointer (241) and a movable base (242), the cross-line laser pointer (241) being disposed on top of a vertical rod (243) of the movable base (242).
9. The boron neutron capture therapy positioning system of any of claims 1 to 7, wherein the positioning portion (100) and the positioning portion (200) are positioned in unison.
CN202011608140.9A 2020-12-30 2020-12-30 Positioning system for boron neutron capture therapy Pending CN112675442A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011608140.9A CN112675442A (en) 2020-12-30 2020-12-30 Positioning system for boron neutron capture therapy

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Application Number Priority Date Filing Date Title
CN202011608140.9A CN112675442A (en) 2020-12-30 2020-12-30 Positioning system for boron neutron capture therapy

Publications (1)

Publication Number Publication Date
CN112675442A true CN112675442A (en) 2021-04-20

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113181567A (en) * 2021-06-04 2021-07-30 上海市肺科医院 Radiotherapy positioning device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113181567A (en) * 2021-06-04 2021-07-30 上海市肺科医院 Radiotherapy positioning device
CN113181567B (en) * 2021-06-04 2023-03-07 上海市肺科医院 Radiotherapy positioning device

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