CN107007629B - Pearl powder zinc oxide ointment - Google Patents
Pearl powder zinc oxide ointment Download PDFInfo
- Publication number
- CN107007629B CN107007629B CN201710183718.2A CN201710183718A CN107007629B CN 107007629 B CN107007629 B CN 107007629B CN 201710183718 A CN201710183718 A CN 201710183718A CN 107007629 B CN107007629 B CN 107007629B
- Authority
- CN
- China
- Prior art keywords
- zinc oxide
- pearl powder
- ointment
- powder
- vaseline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a pearl powder zinc oxide ointment. The ointment comprises zinc oxide, Margarita powder and vaseline. Also discloses a preparation method of the pearl powder zinc oxide ointment, which comprises the following steps: 1) grinding zinc oxide and pearl powder into powder respectively, sieving, weighing according to a ratio, and mixing for later use; 2) heating vaseline to melt, adding the above mixed powder, stirring, and making into ointment. Also discloses application of the pearl powder zinc oxide ointment in preparing a medicament for treating skin inflammation. The medicine has the obvious effects of protecting skin and promoting skin healing, has good effects on light, medium and severe incontinent dermatitis, and has short treatment time and high cure rate.
Description
Technical Field
The invention relates to a pearl powder zinc oxide ointment.
Background
Incontinence dermatitis (IAD) is a common complication of incontinence patients, and is clinically manifested as pruritus perianal and perineal, discomfort, even skin ulceration and infection. Incontinence patients are subjected to great physical and mental stress, with increased care effort. Therefore, treatment and care of IAD have become an urgent problem to be solved in medical and care work. Skin protectants are products that are widely used clinically to prevent and treat the development of IAD, to isolate and protect the skin from excessive moisture, urine and feces. The skin protectant can be used to effectively prevent IAD and reduce incidence of IAD. Meanwhile, the clinical skin protective agents are various in types, and an effective tool for evaluating the IAD prevention effect of different products is not available up to now.
Zinc oxide is skin protectant, is prepared from zinc oxide and vaseline, has astringent and antibacterial effects, and can react with free fatty acid in oil to generate zinc oleate and zinc oleate, which can moisten and protect skin, and has sorption and drying functions. In addition, the nucleic acid can be absorbed into cells through hair follicles to promote the synthesis of nucleic acid and nucleoprotein, participate in energy metabolism of cells and play a role in promoting tissue repair. Has effects in removing necrotic tissue, promoting granulation, resisting infection, astringing wound, and promoting wound healing, and can be used for preventing and treating perianal red swelling, skin rash, and erosion.
Pearl is a famous and precious traditional Chinese medicine, has more than two thousand years of medicinal history in China, is sweet, salty and cold in nature, enters heart and liver channels, and has the effects of soothing nerves, arresting convulsion, improving eyesight, eliminating nebula, detoxifying and promoting granulation. Calcium carbonate contained in Margarita has strong inhibiting effect on bacteria, and can be used for external application for increasing cell proliferation and differentiation, improving blood circulation, promoting granulation, and promoting wound healing. The Margarita powder is effective in promoting blood circulation of wound surface, astringing wound surface, promoting granulation of ulcer surface, accelerating subsidence of red swelling, promoting wound surface scabbing and healing, and promoting recovery of perianal damaged skin.
Disclosure of Invention
The invention aims to provide a pearl powder zinc oxide ointment.
The technical scheme adopted by the invention is as follows:
a Margarita powder and zinc oxide ointment comprises zinc oxide, Margarita powder and vaseline.
The mass ratio of the mixed mass of the zinc oxide and the pearl powder to the vaseline is 1: (17-19).
The mass ratio of the zinc oxide to the pearl powder is (0.5-2): (0.1 to 1.5).
The mass ratio of the zinc oxide to the pearl powder is 1: 1.
The zinc oxide is more than or equal to 0.3g, and the pearl powder is more than or equal to 0.3 g.
The preparation method of the pearl powder zinc oxide ointment comprises the following steps:
1) grinding zinc oxide and pearl powder into powder respectively, sieving, weighing according to a ratio, and mixing for later use;
2) heating vaseline to melt, adding the above mixed powder, stirring, and making into ointment.
The zinc oxide and the pearl powder are respectively sieved by a 100-mesh sieve.
The heating temperature of the vaseline is 55-65 ℃.
The pearl powder zinc oxide ointment is applied to the preparation of the medicine for treating the skin inflammation.
The skin inflammation is incontinence dermatitis.
The invention has the beneficial effects that:
the medicine has the obvious effects of protecting skin and promoting skin healing, has good effects on light, medium and severe incontinent dermatitis, and has short treatment time and high cure rate.
Detailed Description
A Margarita powder and zinc oxide ointment comprises zinc oxide, Margarita powder and vaseline.
Preferably, the mass ratio of the mixed mass of the zinc oxide and the pearl powder to the vaseline is 1: (17-19).
Preferably, the mass ratio of the zinc oxide to the pearl powder is (0.5-2): (0.1 to 1.5); further preferably, the mass ratio of the zinc oxide to the pearl powder is 1: 1.
Furthermore, the zinc oxide is more than or equal to 0.3g, and the pearl powder is more than or equal to 0.3 g.
The preparation method of the pearl powder zinc oxide ointment comprises the following steps:
1) grinding zinc oxide and pearl powder into powder respectively, sieving, weighing according to a ratio, and mixing for later use;
2) heating vaseline to melt, adding the above mixed powder, stirring, and making into ointment.
Preferably, the zinc oxide and the pearl powder are respectively sieved by a 100-mesh sieve.
Preferably, the heating temperature of the vaseline is 55-65 ℃; further preferably, the heating temperature of the vaseline is 58-62 ℃.
The pearl powder zinc oxide ointment is applied to the preparation of the medicine for treating the skin inflammation.
Preferably, the skin inflammation is incontinence dermatitis.
The present invention will be described in further detail with reference to specific examples.
Example 1:
a pearl powder-zinc oxide ointment comprises zinc oxide 1g, pearl powder 1g, and vaseline 34 g. The preparation method of the ointment comprises the following steps: 1) respectively grinding zinc oxide and pearl powder into powder, sieving with a 100-mesh sieve, weighing according to a ratio, and mixing for later use; 2) heating vaseline to 60 deg.C for melting, adding the above mixed powder, stirring, and making into ointment.
Example 2:
a pearl powder-zinc oxide ointment comprises zinc oxide 2.5g, pearl powder 2.5g, and vaseline 90 g. The preparation method of the ointment comprises the following steps: 1) respectively grinding zinc oxide and pearl powder into powder, sieving with a 100-mesh sieve, weighing according to a ratio, and mixing for later use; 2) heating vaseline to 62 deg.C to melt, adding the above mixed powder, stirring, and making into ointment.
The medicine is a fine and soft milky ointment, has proper viscosity, is easy to be coated on skin or mucous membrane, does not melt, and has small viscosity which changes along with seasons; deterioration phenomena such as rancidity, foreign odor, discoloration and hardening should be avoided; the mixed powder of zinc oxide and pearl powder should be uniformly dispersed in vaseline to form a fine ointment.
The quality inspection of the invention shall conform to the regulations of 0109 ointment under the four-part general regulation of 'Chinese pharmacopoeia' 2015 edition:
granularity: a proper amount of a test sample is taken and placed on a glass slide to be coated into a thin layer, the area of the thin layer is equivalent to that of a cover glass, 3 pieces of the test sample are coated in total, and particles with the particle size of more than 180 mu m cannot be detected according to a particle size and particle size distribution determination method (a first method of 0982).
Loading: the contents should be checked in accordance with the minimum load check method (standard 0942).
The microbial limit: the test should be performed according to the microorganism counting method (rule 1105), the controlled bacteria test method (rule 1106) and the non-sterile medicine microorganism limit standard (rule 1107) and should be in accordance with the regulations.
The effect is as follows:
the medicine has good treatment effect and has good effect on light, medium and severe incontinent dermatitis.
Mild: the skin was intact with mild redness and discomfort. The traditional Chinese medicine is directly applied after cleaning the skin, and the skin is generally healed within 2 to 3 days.
Medium: moderate redness, skin exfoliation, small blisters or a small area of damaged cortex with pain or discomfort.
Cleaning with normal saline, and directly applying the medicine, wherein the medicine is generally cured within 3-5 days.
And (3) severe degree: darkening or deep redness of the skin, extensive skin exfoliation damage, blisters and exudation. Cleaning with normal saline, and directly applying the medicine, wherein the medicine is generally cured within 7-10 days.
The medicine has obvious effects of protecting skin and promoting skin healing. Short treatment time and high cure rate. The application method comprises applying the composition to affected part of incontinence dermatitis with a thickness of 0.5mm and a thickness of 2cm larger than that of erythema, erythema or injury, 3-4 times per day.
The following cases are exemplified.
(1) Diagnosis of A patient in encephalopathy: acute cerebral infarction. The patient is kept with a tracheotomy indwelling tube, a stomach tube and a urinary catheter. The patient has the symptoms of multiple times of defecating, dark red perianal skin, large-area skin peeling and damage, exudation and blood seepage, and white or yellow blister and exudation on part of the skin. Is severe incontinence dermatitis. The medicine is used, combined with antidiarrheal medicines and nasal feeding, and the patient can be cured in 8 days.
(2) Diagnosis of cardiovascular disease patient B: coronary atherosclerotic heart disease. Cough, expectoration, abdominal distention, abdominal pain, urinary incontinence, intact skin, and slight redness of skin around perineum. The medicine is used for treating mild incontinence dermatitis, and is combined with an indwelling catheter, so that the mild incontinence dermatitis can be cured within 2 days.
(3) Diagnosis of patient of encephalopathy: hypertensive cerebral hemorrhage. The patient keeps somewhere intestines and nasal tube, stomach tube, tracheotomy sleeve pipe, PICC pipe and ureter. At present, the anus is continuously moist, yellow brown color is overflowed and rotten, the anus is eroded and flushed, and a little blood seeps. Is severe incontinence dermatitis. The medicine is used, combined with antidiarrheal medicines and nasal feeding, and the patient can be cured in 8 days.
(4) Diagnosis of craniocerebral patients D: hypertensive cerebral hemorrhage. The patient has weakness in the left limb and is placed in the lumbar cisterna to drain. After patients had defecated 4 times daily, perianal flushing appeared, with partial skin damage. Moderate incontinent dermatitis. The medicine is combined with antidiarrheal medicines for diet therapy, and the disease can be cured in 5 days.
Claims (1)
1. Application of Margarita powder and zinc oxide ointment in preparing medicine for treating incontinence dermatitis;
the pearl powder and zinc oxide ointment consists of zinc oxide, pearl powder and vaseline; the mass ratio of the mixed mass of the zinc oxide and the pearl powder to the vaseline is 1: (17-19); the mass ratio of the zinc oxide to the pearl powder is 1: 1; the zinc oxide is more than or equal to 0.3g, and the pearl powder is more than or equal to 0.3 g;
the pearl powder zinc oxide ointment is prepared by the following preparation method, and comprises the following steps: 1) grinding zinc oxide and pearl powder into powder respectively, sieving, weighing according to a ratio, and mixing for later use; the zinc oxide and the pearl powder are respectively sieved by a 100-mesh sieve; 2) heating and melting vaseline, adding the above mixed powder, stirring, and making into ointment; the heating temperature of the vaseline is 55-65 ℃;
the pearl powder zinc oxide ointment is used by the following steps: applying Margarita powder zinc oxide ointment to affected part of incontinence dermatitis with a thickness of 0.5mm and a range of 2cm greater than that of erythema, erythema or injury, 3-4 times per day.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710183718.2A CN107007629B (en) | 2017-03-24 | 2017-03-24 | Pearl powder zinc oxide ointment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710183718.2A CN107007629B (en) | 2017-03-24 | 2017-03-24 | Pearl powder zinc oxide ointment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107007629A CN107007629A (en) | 2017-08-04 |
| CN107007629B true CN107007629B (en) | 2020-04-28 |
Family
ID=59445376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710183718.2A Active CN107007629B (en) | 2017-03-24 | 2017-03-24 | Pearl powder zinc oxide ointment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107007629B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8980344B2 (en) * | 2007-10-01 | 2015-03-17 | Dennis F. Gross | Skin care products containing multiple enhancers |
-
2017
- 2017-03-24 CN CN201710183718.2A patent/CN107007629B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107007629A (en) | 2017-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Vogler et al. | Aloe vera: a systematic review of its clinical effectiveness. | |
| CN105395467B (en) | A kind of Chinese medicine composition, skin beautifying cosmetic and its application | |
| CN114159511B (en) | Traditional Chinese medicine preparation for preventing and treating radioactive skin injury and preparation method thereof | |
| CN107007629B (en) | Pearl powder zinc oxide ointment | |
| CN105616648A (en) | Chinese and western integrated medicine composition treating diaper dermatitis of new born children, and preparation method of Chinese and western integrated medicine composition | |
| CN102552695B (en) | Medicine for treating burn and preparation method thereof | |
| WO2016115768A1 (en) | Burn ointment for promoting tissue regeneration and skin growth, and preparation method therefor | |
| CN101904932B (en) | External application Chinese ointment for preventing and curing skin injury caused by ionizing radiation | |
| CN105031254B (en) | A kind of paste and preparation method thereof for treating dermatitis | |
| CN110559378B (en) | Compound sugar foot pulse-activating ointment and preparation method thereof | |
| CN107050060A (en) | Treat psoriasic externally applied drug and pharmaceutical composition | |
| CN1057467C (en) | Medicine for treating impetigo | |
| CN101732567B (en) | Medicament for treating burns and preparation method thereof | |
| CN105168629A (en) | Traditional Chinese medicine gel for treating qi-stagnation and blood stasis type decubitus | |
| CN1062128C (en) | Ointment for eliminating tinea | |
| CN104606340A (en) | Purely natural traditional Chinese medicine repair skin and tissue cream | |
| CN112057576B (en) | Kidney-reinforcing and urination-reducing nocturia acupoint patch and preparation method thereof | |
| CN113332365B (en) | Compound lithospermum ointment and preparation method thereof | |
| CN1141774A (en) | Formular of medicine for preventing and curing eczema resulted from baby's napkin | |
| CN109364205B (en) | Traditional Chinese medicine composition with skin freckle removing effect, aqueous extract and fermentation product of traditional Chinese medicine composition and application of traditional Chinese medicine composition | |
| CN105902722B (en) | Traditional Chinese medicine composition for treating leucoderma as well as preparation method and application thereof | |
| CN100387289C (en) | Canine oil ointment for curing burn and stopping pain | |
| CN101869578B (en) | External liniment for drawing pus out and diminishing inflammation | |
| Song et al. | Evaluation of the Therapeutic Effect of Preventive External Application of Traditional Chinese Medicine Gel Combined with Psychological Care in Tumor Patients with Radiation Dermatitis | |
| CN105267386A (en) | Fever cooling patch |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |