CN107007250B - A kind of fundus imaging optical system - Google Patents

A kind of fundus imaging optical system Download PDF

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Publication number
CN107007250B
CN107007250B CN201710399042.0A CN201710399042A CN107007250B CN 107007250 B CN107007250 B CN 107007250B CN 201710399042 A CN201710399042 A CN 201710399042A CN 107007250 B CN107007250 B CN 107007250B
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light
array
lens
polarizer
optical system
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CN201710399042.0A
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CN107007250A (en
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邓宇
陈惠雄
郭钟宁
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Guangdong University of Technology
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Guangdong University of Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1025Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for confocal scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

The invention discloses a kind of fundus imaging optical system, the light that polarizer is used to issue in light source portion carries out phase shift conversion;Polarizer, the first array of orifices plate and microlens array are sequentially arranged along optical path, and microlens array includes the multiple lenticules arranged in the same plane, and multiple lenticules are used to focus respectively to by light, form the different multichannel light beam in the direction of propagation;First lens are used to the light being emitted by microlens array converging to eyeground position;First array of orifices plate is used to generate the light that light successively returns after the first lens, microlens array by eyeground position, and is incident on polarizer;Second lens are used to the light that return light is emitted through polarizer converging to second orifice array board;Photoelectronic imaging device is used to receive second orifice array board and passes through light and be imaged.Fundus imaging optical system of the present invention can form the imaging of the same focussing plane in eyeground position, it can be achieved that the high-precision at eyeground position is imaged, and increases scope of sight.

Description

A kind of fundus imaging optical system
Technical field
The present invention relates to optical application technical fields, more particularly to a kind of fundus imaging optical system.
Background technique
The health of eyes is particularly important.Funduscopy is that one of eye health and treatment commonly use detection methods, can Observation or imaging form the image of inside of eye and retina, observe eye ground, or tracking diseased region.
In the prior art, the equipment of funduscopy includes Laser Scanning Confocal Microscope, and Laser Scanning Confocal Microscope is that a kind of high-precision is aobvious Micro mirror is the optical profile testing image of sample based on its image-forming principle Confocal Images obtained, is obtained by demixing scan Multilayer cross-sectional image can construct three-dimensional imaging.Laser Scanning Confocal Microscope carries out imaging using pin hole, and imaging precision can be improved, But have the shortcomings that scope of sight is small.
Summary of the invention
The object of the present invention is to provide a kind of fundus imaging optical system, it can be achieved that the high-precision at eyeground position is imaged, and And scope of sight can be increased compared with prior art.
To achieve the above object, the present invention provides the following technical solutions:
A kind of fundus imaging optical system, including light source portion, polarizer, the first array of orifices plate, microlens array, One lens, the second lens, second orifice array board and photoelectronic imaging device;
The light that the polarizer is used to issue in the light source portion carries out phase shift conversion;
The polarizer, the first array of orifices plate and the microlens array are sequentially arranged along optical path, described micro- Lens array includes the multiple lenticules arranged in the same plane, and multiple lenticules are used to focus respectively to by light, Form the different multichannel light beam in the direction of propagation;
First lens are used to the light being emitted by the microlens array converging to eyeground position;
The first array of orifices plate, which is used to generate light by eyeground position, successively passes through first lens, described micro- The light returned after lens array, and it is incident on the polarizer;
Second lens are used to the light that return light is emitted through the polarizer converging to the second orifice array Plate;
The photoelectronic imaging device is used to receive the second orifice array board and passes through light and be imaged.
Optionally, the first array of orifices plate, the microlens array and first lens are located at the polarization member On the direction of part transmitted light outgoing, second lens, the second orifice array board and the photoelectronic imaging device are located at institute On the direction for stating the outgoing of polarizer reflected light.
Optionally, the first array of orifices plate, the microlens array and first lens are located at the polarization member On the direction of part reflected light outgoing, second lens, the second orifice array board and the photoelectronic imaging device are located at institute On the direction for stating the outgoing of polarizer transmitted light.
Optionally, amendment microscope group is provided between the polarizer and the microlens array;
The amendment microscope group is used to the light returned by the microlens array converging to the first array of orifices plate.
Optionally, the amendment microscope group is also used to correct by the aperture of the polarizer emergent light.
Optionally, the light source portion includes:
For issuing the laser of laser;
What the laser for issuing to the laser was expanded and collimated expands microscope group.
Optionally, the lenticule is that deformation occurs and then the lens of change focal length under power-on voltage control.
Optionally, multiple lenticules are uniformly distributed in the same plane.
Optionally, reflecting element, the lenticule battle array are provided between the microlens array and first lens The emergent light of column is incident on the reflecting element, and light is reflexed to first lens by the reflecting element.
As shown from the above technical solution, fundus imaging optical system provided by the present invention, including light source portion, polarization member Part, the first array of orifices plate, microlens array, the first lens, the second lens, second orifice array board and photoelectronic imaging device.
Light source portion issues light, and light carries out phase shift conversion by polarizer, and light passes through microlens array, lenticule after conversion Multiple lenticules of array form the different multichannel light beam in the direction of propagation to being focused respectively by light, and the first lens are by lenticule The light of array outgoing converges to eyeground position, converges to eyeground position different location respectively.Eyeground position each position generate light according to It is secondary to pass through the first lens, microlens array, and polarizer is incident on by the first array of orifices plate light hole;Second lens will The light that return light is emitted through the polarizer converges to second orifice array board, receives second orifice battle array by photoelectronic imaging device Strake passes through light and is imaged.
Fundus imaging optical system of the present invention, the imaging of the same focussing plane in eyeground position or curved surface can be formed, it can be achieved that The high-precision at eyeground position is imaged, and increases scope of sight.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.
Fig. 1 is a kind of schematic diagram of fundus imaging optical system provided in an embodiment of the present invention;
Fig. 2 is a kind of schematic diagram for fundus imaging optical system that further embodiment of this invention provides;
Fig. 3 is the schematic diagram in light source portion in the embodiment of the present invention;
Fig. 4 is a kind of schematic diagram for fundus imaging optical system that further embodiment of this invention provides.
Specific embodiment
Technical solution in order to enable those skilled in the art to better understand the present invention, below in conjunction with of the invention real The attached drawing in example is applied, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common Technical staff's every other embodiment obtained without making creative work, all should belong to protection of the present invention Range.
A kind of fundus imaging optical system provided in an embodiment of the present invention, including light source portion, polarizer, the first aperture battle array Strake, microlens array, the first lens, the second lens, second orifice array board and photoelectronic imaging device;
The light that the polarizer is used to issue in the light source portion carries out phase shift conversion;
The polarizer, the first array of orifices plate and the microlens array are sequentially arranged along optical path, described micro- Lens array includes the multiple lenticules arranged in the same plane, and multiple lenticules are used to focus respectively to by light, Form the different multichannel light beam in the direction of propagation;
First lens are used to the light being emitted by the microlens array converging to eyeground position;
The first array of orifices plate, which is used to generate light by eyeground position, successively passes through first lens, described micro- The light returned after lens array, and it is incident on the polarizer;
Second lens are used to the light that return light is emitted through the polarizer converging to the second orifice array Plate;
The photoelectronic imaging device is used to receive the second orifice array board and passes through light and be imaged.
Wherein, light source portion issues light, preferably sending collimated light, is incident on polarizer.
The polarizer, the first array of orifices plate, the microlens array are sequentially arranged along optical path.Polarizer Phase shift conversion is carried out to by light, makes to project eyeground position by light change polarization direction, avoids the projection light of outgoing and return Light echo generates interference.
First array of orifices plate, microlens array are successively passed through by the light that polarizer is emitted.Wherein, microlens array has There are the multiple lenticules arranged in the same plane, multiple lenticules focus respectively to by light, and it is different to form the direction of propagation Multichannel light beam.The different each road light in the direction of propagation is converged to eyeground position different location by the first lens respectively.
For light projection at the different location of eyeground position, eyeground position, which is excited, generates light or generation reflected light, eyeground portion Position generates light successively after the first lens, microlens array, is passed through by each aperture on the first array of orifices plate, by it is each Road light returns to polarizer.The light that return light is emitted through polarizer is converged to second orifice array board by the second lens, by Photoelectronic imaging device receives second orifice array board and passes through light and be imaged.
The present embodiment fundus imaging optical system can form the imaging of the same focussing plane in eyeground position or curved surface, can It realizes the high-precision imaging at eyeground position, and increases scope of sight.
The present embodiment fundus imaging optical system is described in detail below.
Fig. 1 or Fig. 2 is please referred to, this fundus imaging optical system includes light source portion 10, polarizer 11, the first array of orifices Plate 12, microlens array 13, the first lens 14, the second lens 15, second orifice array board 16 and photoelectronic imaging device 17.
In the specific implementation, referring to FIG. 3, light source portion 10 may include:
For issuing the laser 100 of laser;
What the laser for issuing to the laser 100 was expanded and collimated expands microscope group 101.
The angle of divergence, Energy distribution and the beam diameter that 100 output light of laser is adjusted by expanding microscope group 101, to generation Laser is expanded and is collimated, and collimation light output is formed.
Polarizer 11, which is used to the light source portion 10 issuing light, carries out phase shift conversion.In the specific implementation, polarizer 11 can be used polarization beam splitter.
In a specific embodiment, Fig. 1, the first array of orifices plate 12, the microlens array 13 be can refer to It is located on the direction of 11 transmitted light of polarizer outgoing with first lens 14, second lens 15, described second Array of orifices plate 16 and the photoelectronic imaging device 17 are located on the direction of 11 reflected light of polarizer outgoing.
By the light transmitted after 11 phase shift of polarizer conversion, 90 degree of change of polarized direction, the first aperture battle array is passed sequentially through Strake 12 and microlens array 13.
Microlens array 13 includes the multiple lenticules arranged in the same plane, and multiple lenticules are used for by light point It does not focus, forms the different multichannel light beam in the direction of propagation.Wherein, under an imaging detection state, the focal length phase of multiple lenticules Together, light is focused respectively by multiple lenticules, forms the different multichannel light beam in the direction of propagation, make light projection to eyeground position not At position.
In the specific implementation, the position of multiple lenticules is arranged flexible setting in microlens array 13, a kind of excellent It selects in mode, multiple lenticules are uniformly distributed in the same plane.
First lens 14 are used to the light being emitted by the microlens array 13 converging to eyeground position.By lenticule Each road light for the different directions of propagation that array 13 is emitted converges to eyeground position different location by the first lens 14 respectively.
Light projection is to eyeground position, and eyeground position, which is excited, to be generated light or generate reflected light, and eyeground position each position produces The third contact of a total solar or lunar eclipse successively passes through the first lens, microlens array, and is passed through by each light hole on the first array of orifices plate 12, to return Each road light amendment.
Polarizer is returned to by the light of the first array of orifices plate 12, is reflected to the second lens 15.Second lens 15 The light that return light is emitted through the polarizer 11 is converged into the second orifice array board 16.
Photoelectronic imaging device 17 receives the second orifice array board 16 and passes through light and be imaged.
Preferably, the multiple light holes being distributed on the first array of orifices plate 12, second orifice array board 16 are uniformly distributed.
In the specific implementation, optionally, charge-coupled image sensor, i.e. ccd image can be used in photoelectronic imaging device 17 Sensor.
In another embodiment specific implementation mode, Fig. 2, the first array of orifices plate 12, the microlens array be can refer to 13 and first lens 14 be located on the direction of 11 reflected light of polarizer outgoing, second lens 15, described the Two array of orifices plates 16 are located on the direction of 11 transmitted light of polarizer outgoing.
Wherein, the light gone out by 11 phase shift of polarizer conversion back reflection, 90 degree of change of polarized direction, it is small to pass sequentially through first Hole array plate 12 and microlens array 13.
Microlens array 13 focuses respectively to by light, forms the different multichannel light beam in the direction of propagation.First lens 14 will Eyeground position different location is converged to by each road light that the microlens array 13 is emitted respectively.
Eyeground position each position generates light and successively passes through the first lens 14, microlens array 13, and passes through the first aperture battle array Each light hole passes through on strake 12, returns to polarizer by the light of the first array of orifices plate 12, is transmitted to the second lens 15.The light that return light is emitted through the polarizer 11 is converged to second orifice array board 16 by the second lens 15.Photoelectronic imaging Device 17 receives second orifice array board 16 and passes through light and be imaged.
In present embodiment, the specific set-up mode of each optical element can refer to embodiment description, herein not It repeats again.
Preferably, in the respective embodiments described above, the lenticule of microlens array 13 is to occur under power-on voltage control Deformation and then the lens for changing focal length.In to eyeground image areas observation process, microlens array 13 can be changed by control Power-on voltage, control changes each lenticule focal length, and the imaging of Observable eyeground position difference focussing plane is realized to eyeground portion The imaging observation of each scanning level in position.
Further, in the respective embodiments described above, it is set between the polarizer 11 and the microlens array 13 It is equipped with amendment microscope group 18;The amendment microscope group 18 is used to the light returned by microlens array 13 converging to the first array of orifices plate 12, it can refer to shown in Fig. 4.
The amendment microscope group 18 is also used to correct by the aperture of 11 emergent light of polarizer.
Specifically, the amendment microscope group 18 is made of concave mirror or/and convex mirror, concave mirror or convex mirror can be ball Face lens are non-spherical lens.
Further, reflecting element 20 is provided between the microlens array 13 and first lens 14, it is described The emergent light of microlens array 13 is incident on the reflecting element 20, and light is reflexed to first lens by the reflecting element 20 14.It can change optical path direction by reflecting element 20, be more convenient for optical system structure layout and light path design.
Illustratively, in a specific embodiment, the size of array of orifices plate is 20mmX20mm, the diameter of light hole It is 25 μm, there is 600X600 light hole altogether.
The present embodiment fundus imaging optical system is realized using microlens array and array of orifices plate to eyeground position Big scope of sight imaging, compared with existing Laser Scanning Confocal Microscope, can be improved image taking speed and imaging precision.Also, using to micro- The Zoom control of lens array segments irradiation light, and each road light is focused in different location, it can be achieved that 3-D scanning is imaged.
A kind of fundus imaging optical system provided by the present invention is described in detail above.Tool used herein Principle and implementation of the present invention are described for body example, the above embodiments are only used to help understand this hair Bright method and its core concept.It should be pointed out that for those skilled in the art, not departing from the present invention , can be with several improvements and modifications are made to the present invention under the premise of principle, these improvement and modification also fall into right of the present invention It is required that protection scope in.

Claims (9)

1. a kind of fundus imaging optical system, including photoelectronic imaging device, which is characterized in that further include light source portion, polarizer, First array of orifices plate, microlens array, the first lens, the second lens, second orifice array board;
The light that the polarizer is used to issue in the light source portion carries out phase shift conversion;
The polarizer, the first array of orifices plate and the microlens array are sequentially arranged along optical path, the lenticule Array includes the multiple lenticules arranged in the same plane, and multiple lenticules are used to focus respectively to by light, be formed The different multichannel light beam in the direction of propagation;
First lens are used to the light being emitted by the microlens array converging to eyeground position;
The first array of orifices plate, which is used to generate light by eyeground position, successively passes through first lens, the lenticule battle array The light returned after column, and it is incident on the polarizer;
Second lens are used to the light that return light is emitted through the polarizer converging to the second orifice array board;
The photoelectronic imaging device is used to receive the second orifice array board and passes through light and be imaged.
2. fundus imaging optical system according to claim 1, which is characterized in that the first array of orifices plate, described Microlens array and first lens are located on the direction of polarizer transmitted light outgoing, second lens, described Second orifice array board and the photoelectronic imaging device are located on the direction of polarizer reflected light outgoing.
3. fundus imaging optical system according to claim 1, which is characterized in that the first array of orifices plate, described Microlens array and first lens are located on the direction of polarizer reflected light outgoing, second lens, described Second orifice array board and the photoelectronic imaging device are located on the direction of polarizer transmitted light outgoing.
4. fundus imaging optical system according to claim 1-3, which is characterized in that in the polarizer and Amendment microscope group is provided between the microlens array;
The amendment microscope group is used to the light returned by the microlens array converging to the first array of orifices plate.
5. fundus imaging optical system according to claim 4, which is characterized in that the amendment microscope group be also used to correct by The aperture of the polarizer emergent light.
6. fundus imaging optical system according to claim 1-3, which is characterized in that the light source portion includes:
For issuing the laser of laser;
What the laser for issuing to the laser was expanded and collimated expands microscope group.
7. fundus imaging optical system according to claim 1-3, which is characterized in that the lenticule is logical The lower lens that deformation occurs and then changes focal length of piezoelectric voltage control.
8. fundus imaging optical system according to claim 7, which is characterized in that multiple lenticules are in same plane Inside it is uniformly distributed.
9. fundus imaging optical system according to claim 1, which is characterized in that in the microlens array and described the Reflecting element is provided between one lens, the emergent light of the microlens array is incident on the reflecting element, the reflective member Light is reflexed to first lens by part.
CN201710399042.0A 2017-05-31 2017-05-31 A kind of fundus imaging optical system Expired - Fee Related CN107007250B (en)

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CN112714636B (en) * 2018-09-18 2022-12-13 国神光电科技(上海)有限公司 Medical treatment system and method using a series of pulsed lasers
CN110448266B (en) * 2018-12-29 2022-03-04 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 Random laser confocal line scanning three-dimensional ophthalmoscope and imaging method
US11543640B2 (en) * 2020-04-21 2023-01-03 Laxco Incorporated Confocal optical system and components thereof
CN115153422A (en) * 2022-05-30 2022-10-11 清华大学 Fundus imaging method and system based on element imaging
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