CN106999622A - 包含生物玻璃的抗微生物组合物 - Google Patents
包含生物玻璃的抗微生物组合物 Download PDFInfo
- Publication number
- CN106999622A CN106999622A CN201580065698.8A CN201580065698A CN106999622A CN 106999622 A CN106999622 A CN 106999622A CN 201580065698 A CN201580065698 A CN 201580065698A CN 106999622 A CN106999622 A CN 106999622A
- Authority
- CN
- China
- Prior art keywords
- composition
- antimicrobial
- weight
- composition according
- wound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0004—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/206—Biguanides, e.g. chlorohexidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/208—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462087270P | 2014-12-04 | 2014-12-04 | |
| US62/087,270 | 2014-12-04 | ||
| PCT/US2015/062911 WO2016089731A1 (en) | 2014-12-04 | 2015-11-30 | Antimicrobial compositions comprising bioglass |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106999622A true CN106999622A (zh) | 2017-08-01 |
Family
ID=54848907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580065698.8A Pending CN106999622A (zh) | 2014-12-04 | 2015-11-30 | 包含生物玻璃的抗微生物组合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20180303873A1 (enExample) |
| EP (1) | EP3226921B1 (enExample) |
| JP (1) | JP2017536402A (enExample) |
| CN (1) | CN106999622A (enExample) |
| WO (1) | WO2016089731A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| CN103347561B (zh) | 2010-12-08 | 2016-09-07 | 康沃特克科技公司 | 用于评估伤口分泌液的集成系统 |
| EP4162968A1 (en) | 2010-12-08 | 2023-04-12 | ConvaTec Technologies Inc. | System for removing exudates from a wound site |
| JP6151186B2 (ja) | 2010-12-08 | 2017-06-21 | コンバテック・テクノロジーズ・インコーポレイテッドConvatec Technologies Inc | 創傷滲出液システム付属装置 |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| CN105008611A (zh) | 2012-12-20 | 2015-10-28 | 康沃特克科技公司 | 化学改性的纤维素纤维的处理 |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| CA3019436A1 (en) | 2016-03-30 | 2017-10-05 | Qualizyme Diagnostics Gmbh & Co Kg | Detecting microbial infection in wounds |
| CN109310528B (zh) | 2016-03-30 | 2021-07-20 | 康沃特克科技公司 | 检测伤口中的微生物感染 |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| TW201805034A (zh) | 2016-07-08 | 2018-02-16 | 美商康瓦鐵克科技股份有限公司 | 彈性的負壓系統 |
| US11266774B2 (en) | 2016-07-08 | 2022-03-08 | Convatec Technologies Inc. | Fluid collection apparatus |
| PL3481360T3 (pl) | 2016-07-08 | 2022-05-02 | Convatec Technologies Inc. | Wykrywanie przepływu płynu |
| US12161792B2 (en) | 2017-11-16 | 2024-12-10 | Convatec Limited | Fluid collection apparatus |
| DE102018114946B3 (de) | 2018-06-21 | 2019-04-25 | Klinikum Nürnberg Medical School GmbH | Bioaktiver Träger |
| US11896612B2 (en) | 2019-03-29 | 2024-02-13 | Board Of Trustees Of Michigan State University | Resurrection of antibiotics that MRSA resists by silver-doped bioactive glass-ceramic particles |
| JP7511585B2 (ja) | 2019-06-03 | 2024-07-05 | コンバテック リミティド | 病原体を破壊して封じ込めるための方法およびデバイス |
| DE102019124879A1 (de) | 2019-08-03 | 2021-02-04 | Klinikum Nürnberg Medical School GmbH | Bioaktiver Träger |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| DE102024102919A1 (de) | 2024-02-01 | 2025-08-07 | Giesecke+Devrient Currency Technology Gmbh | Antimikrobieller lack durch polymerwirkstoff |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050058673A1 (en) * | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| CN101473058A (zh) * | 2006-06-21 | 2009-07-01 | 旭硝子欧洲平板玻璃股份有限公司 | 具有抗微生物性能的基材 |
| CN101883663A (zh) * | 2007-10-16 | 2010-11-10 | Hkpb科技有限公司 | 表面涂布方法和其用途 |
| CN101884807A (zh) * | 2010-06-24 | 2010-11-17 | 同济大学 | 一种具有生物活性的硼酸盐玻璃抗菌涂层的制备方法及其应用 |
| CN102170779A (zh) * | 2008-08-28 | 2011-08-31 | 泰科保健集团有限合伙公司 | 抗微生物泡沫组合物,制品和方法 |
| CN103705968A (zh) * | 2013-12-30 | 2014-04-09 | 深圳先进技术研究院 | 一种医用壳聚糖复合保湿敷料及其制备方法 |
| CN103736135A (zh) * | 2013-12-12 | 2014-04-23 | 深圳先进技术研究院 | 一种医用复合敷料及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6756060B1 (en) | 1996-09-19 | 2004-06-29 | Usbiomaterials Corp. | Anti-inflammatory and antimicrobial uses for bioactive glass compositions |
| JP4359943B2 (ja) * | 1997-10-31 | 2009-11-11 | 東亞合成株式会社 | 抗菌剤、抗菌剤組成物及び抗菌性を有する透明性樹脂組成物 |
| PL363113A1 (en) * | 2000-03-27 | 2004-11-15 | Schott Glas | New cosmetic, personal care, cleaning agent, and nutritional supplement compositions comprising bioactive glass and methods of making and using the same |
| JP2005501113A (ja) * | 2001-08-22 | 2005-01-13 | カール−ツァイス−スティフツング | 炎症を抑えて傷を癒す抗菌性のガラス粉末ならびにその使用方法 |
| PL2316567T3 (pl) | 2003-09-26 | 2018-07-31 | 3M Innovative Properties Co. | Katalizatory, środki aktywujące, nośniki i metodologie użyteczne do wytwarzania układów katalizatora, w szczególności gdy katalizator jest osadzany na nośnikach z wykorzystaniem fizycznego osadzania z fazy gazowej |
| US20050249791A1 (en) * | 2004-05-07 | 2005-11-10 | 3M Innovative Properties Company | Antimicrobial articles |
| ITTO20040854A1 (it) * | 2004-12-02 | 2005-03-02 | Torino Politecnico | Procedimento di funzionamento di superfici vetrose, vetroceramiche e ceramiche per la realizzazione di dispositivi impiantabili ad azione antibatterica |
| DE102006009793A1 (de) * | 2005-10-31 | 2007-09-06 | Sus Tech Gmbh & Co. Kg | Verwendung von schwer wasserlöslichen Calciumsalzen und/oder deren Kompositen |
| GB0612028D0 (en) * | 2006-06-16 | 2006-07-26 | Imp Innovations Ltd | Bioactive glass |
| FR2918269B1 (fr) * | 2007-07-06 | 2016-11-25 | Oreal | Composition de protection solaire contenant l'association d'un polymere semi-cristallin et de particules de latex creuses. |
| US9655840B2 (en) * | 2009-12-22 | 2017-05-23 | Rigshospitalet, Copenhagen University Hospital | Wound care products |
| JP2014512324A (ja) * | 2011-03-28 | 2014-05-22 | コーニング インコーポレイテッド | ガラス中の銅の抗微生物作用 |
| EP2736486B1 (en) * | 2011-07-28 | 2019-03-06 | 3M Innovative Properties Company | Wound-healing compositions and method of use |
-
2015
- 2015-11-30 US US15/531,046 patent/US20180303873A1/en not_active Abandoned
- 2015-11-30 CN CN201580065698.8A patent/CN106999622A/zh active Pending
- 2015-11-30 EP EP15808312.1A patent/EP3226921B1/en active Active
- 2015-11-30 JP JP2017529642A patent/JP2017536402A/ja not_active Withdrawn
- 2015-11-30 WO PCT/US2015/062911 patent/WO2016089731A1/en not_active Ceased
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050058673A1 (en) * | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| CN101473058A (zh) * | 2006-06-21 | 2009-07-01 | 旭硝子欧洲平板玻璃股份有限公司 | 具有抗微生物性能的基材 |
| CN101883663A (zh) * | 2007-10-16 | 2010-11-10 | Hkpb科技有限公司 | 表面涂布方法和其用途 |
| CN102170779A (zh) * | 2008-08-28 | 2011-08-31 | 泰科保健集团有限合伙公司 | 抗微生物泡沫组合物,制品和方法 |
| CN101884807A (zh) * | 2010-06-24 | 2010-11-17 | 同济大学 | 一种具有生物活性的硼酸盐玻璃抗菌涂层的制备方法及其应用 |
| CN103736135A (zh) * | 2013-12-12 | 2014-04-23 | 深圳先进技术研究院 | 一种医用复合敷料及其制备方法 |
| CN103705968A (zh) * | 2013-12-30 | 2014-04-09 | 深圳先进技术研究院 | 一种医用壳聚糖复合保湿敷料及其制备方法 |
Non-Patent Citations (1)
| Title |
|---|
| 成昊等: "生物活性玻璃/壳聚糖/羟基磷灰石复合骨修复材料制备及细胞相容性研究", 《生物骨科材料与临床研究》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016089731A1 (en) | 2016-06-09 |
| EP3226921B1 (en) | 2020-08-19 |
| US20180303873A1 (en) | 2018-10-25 |
| EP3226921A1 (en) | 2017-10-11 |
| JP2017536402A (ja) | 2017-12-07 |
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